Tomas Ganz - Publications

Cellular & Molecular Pathology 049D University of California, Los Angeles, Los Angeles, CA 
General Biology, Pathology, Molecular Biology, Biochemistry

335 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Delaney KM, Guillet R, Pressman EK, Ganz T, Nemeth E, O'Brien KO. Serum Erythroferrone During Pregnancy Is Related to Erythropoietin but Does Not Predict the Risk of Anemia. The Journal of Nutrition. PMID 33982118 DOI: 10.1093/jn/nxab093  0.64
2021 Hanudel MR, Wong S, Jung G, Qiao B, Gabayan V, Zuk A, Ganz T. Amelioration of chronic kidney disease-associated anemia by vadadustat in mice is not dependent on erythroferrone. Kidney International. PMID 33811979 DOI: 10.1016/j.kint.2021.03.019  0.64
2021 Goncalves Monteiro D, van Dijk JWA, Aliyanto R, Fung E, Nemeth E, Ganz T, Rosengren J, Clark RJ. Pursuing Orally Bioavailable Hepcidin Analogues via Cyclic -Methylated Mini-Hepcidins. Biomedicines. 9. PMID 33567510 DOI: 10.3390/biomedicines9020164  0.64
2020 Deshpande CN, Azucenas CR, Qiao B, Nomura N, Xin V, Font J, Iwata S, Ganz T, Nemeth E, Mackenzie B, Jormakka M. Isolation and thermal stabilization of mouse ferroportin. Febs Open Bio. PMID 33190422 DOI: 10.1002/2211-5463.13039  0.64
2020 Jerzak KJ, Lohmann AE, Ennis M, Nemeth E, Ganz T, Goodwin PJ. Prognostic associations of plasma hepcidin in women with early breast cancer. Breast Cancer Research and Treatment. PMID 32960376 DOI: 10.1007/S10549-020-05903-Z  0.64
2020 Hsu D, Kim A, Ganz T, Suh JD, Wang M, Wu TJ, Lee JT. Expression of Iron-Regulatory Hormone Hepcidin and Iron Transporters Ferroportin and ZIP8 in Patients With and Without Chronic Rhinosinusitis. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 194599820939910. PMID 32746765 DOI: 10.1177/0194599820939910  0.64
2020 Gutschow P, Han H, Olbina G, Westerman K, Nemeth E, Ganz T, Copeland K, Westerman M, Ostland V. Clinical Immunoassay for Human Hepcidin Predicts Iron Deficiency in First-Time Blood Donors. The Journal of Applied Laboratory Medicine. PMID 32674118 DOI: 10.1093/jalm/jfaa038  0.64
2020 Zhang V, Ganz T, Nemeth E, Kim A. Iron overload causes a mild and transient increase in acute lung injury. Physiological Reports. 8: e14470. PMID 32596989 DOI: 10.14814/Phy2.14470  0.64
2020 Sangkhae V, Fisher AL, Chua KJ, Ruchala P, Ganz T, Nemeth E. Maternal Hepcidin Determines Embryo Iron Homeostasis. Blood. PMID 32584957 DOI: 10.1182/Blood.2020005745  0.64
2020 Kautz L, Jung G, Valore EV, Rivella S, Nemeth E, Ganz T. Author Correction: Identification of erythroferrone as an erythroid regulator of iron metabolism. Nature Genetics. PMID 32107478 DOI: 10.1038/S41588-019-0548-Y  0.64
2020 Fisher AL, Sangkhae V, Presicce P, Chougnet CA, Jobe AH, Kallapur SG, Tabbah SM, Buhimschi CS, Buhimschi IA, Ganz T, Nemeth E. Fetal and amniotic fluid iron homeostasis in healthy and complicated murine, macaque, and human pregnancy. Jci Insight. PMID 31990688 DOI: 10.1172/Jci.Insight.135321  0.64
2019 Sangkhae V, Fisher AL, Wong S, Koenig MD, Tussing-Humphreys L, Chu A, Lelić M, Ganz T, Nemeth E. Effects of maternal iron status on placental and fetal iron homeostasis. The Journal of Clinical Investigation. PMID 31661462 DOI: 10.1172/Jci127341  0.64
2019 Bondu S, Alary AS, Lefèvre C, Houy A, Jung G, Lefebvre T, Rombaut D, Boussaid I, Bousta A, Guillonneau F, Perrier P, Alsafadi S, Wassef M, Margueron R, Rousseau A, ... ... Ganz T, et al. A variant erythroferrone disrupts iron homeostasis in -mutated myelodysplastic syndrome. Science Translational Medicine. 11. PMID 31292266 DOI: 10.1126/Scitranslmed.Aav5467  0.64
2019 Micewicz ED, Iwamoto KS, Ratikan JA, Nguyen C, Xie MW, Cheng G, Boxx GM, Deriu E, Damoiseaux RD, Whitelegge JP, Ruchala PP, Avetisyan R, Jung ME, Lawson G, Nemeth E, ... Ganz T, et al. The Aftermath of Surviving Acute Radiation Hematopoietic Syndrome and its Mitigation. Radiation Research. PMID 30730284 DOI: 10.1667/Rr15231.1  0.64
2019 Chen Q, Yang Y, Hou J, Shu Q, Yin Y, Fu W, Han F, Hou T, Zeng C, Nemeth E, Linzmeier R, Ganz T, Fang X. Increased gene copy number of worsens sepsis by inducing endothelial pyroptosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 30718392 DOI: 10.1073/Pnas.1812947116  0.64
2018 Guo Y, Zhang N, Zhang D, Ren Q, Ganz T, Liu S, Nemeth E. Iron homeostasis in pregnancy and spontaneous abortion. American Journal of Hematology. PMID 30394565 DOI: 10.1002/Ajh.25341  0.64
2018 Gagliano-Jucá T, Pencina KM, Ganz T, Travison TG, Kantoff PW, Nguyen PL, Taplin ME, Kibel AS, Li Z, Huang G, Edwards RR, Nemeth E, Basaria S. Mechanisms Responsible for Reduced Erythropoiesis during Androgen Deprivation Therapy in Men with Prostate Cancer. American Journal of Physiology. Endocrinology and Metabolism. PMID 30325657 DOI: 10.1152/Ajpendo.00272.2018  0.64
2018 Coffey R, Sardo U, Kautz L, Gabayan V, Nemeth E, Ganz T. Erythroferrone is not required for the glucoregulatory and hematologic effects of chronic erythropoietin treatment in mice. Physiological Reports. 6: e13890. PMID 30315639 DOI: 10.14814/Phy2.13890  0.64
2018 Deshpande CN, Ruwe TA, Shawki A, Xin V, Vieth KR, Valore EV, Qiao B, Ganz T, Nemeth E, Mackenzie B, Jormakka M. Calcium is an essential cofactor for metal efflux by the ferroportin transporter family. Nature Communications. 9: 3075. PMID 30082682 DOI: 10.1038/S41467-018-05446-4  0.64
2018 Hanudel MR, Eisenga MF, Rappaport M, Chua K, Qiao B, Jung G, Gabayan V, Gales B, Ramos G, de Jong MA, van Zanden JJ, de Borst MH, Bakker SJL, Nemeth E, Salusky IB, ... ... Ganz T, et al. Effects of erythropoietin on fibroblast growth factor 23 in mice and humans. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. PMID 30007314 DOI: 10.1093/Ndt/Gfy189  0.64
2018 Stefanova D, Raychev A, Deville J, Humphries R, Campeau S, Ruchala P, Nemeth E, Ganz T, Bulut Y. Hepcidin protects against lethal sepsis in mice inoculated with isolates from septic patients. Infection and Immunity. PMID 29735522 DOI: 10.1128/Iai.00253-18  0.64
2018 Meznarich JA, Draper L, Christensen RD, Yaish HM, Luem ND, Pysher TJ, Jung G, Nemeth E, Ganz T, Ward DM. Fetal presentation of congenital dyserythropoietic anemia type 1 with novel compound heterozygous CDAN1 mutations. Blood Cells, Molecules & Diseases. PMID 29599085 DOI: 10.1016/J.Bcmd.2018.03.002  0.64
2018 Adams P, Altes A, Brissot P, Butzeck B, Cabantchik I, Cançado R, Distante S, Evans P, Evans R, Ganz T, Girelli D, Hultcrantz R, McLaren G, Marris B, Milman N, et al. Therapeutic recommendations in HFE hemochromatosis for p.Cys282Tyr (C282Y/C282Y) homozygous genotype. Hepatology International. PMID 29589198 DOI: 10.1007/S12072-018-9855-0  0.64
2018 Hanudel MR, Rappaport M, Chua K, Gabayan V, Qiao B, Jung G, Salusky IB, Ganz T, Nemeth E. Levels of the erythropoietin-responsive hormone erythroferrone in mice and humans with chronic kidney disease. Haematologica. PMID 29419424 DOI: 10.3324/Haematol.2017.181743  0.64
2017 Aschemeyer S, Qiao B, Stefanova D, Valore EV, Sek AC, Ruwe TA, Vieth KR, Jung G, Casu C, Rivella S, Jormakka M, Mackenzie B, Ganz T, Nemeth E. Structure-function analysis of ferroportin defines the binding site and an alternative mechanism of action of hepcidin. Blood. PMID 29237594 DOI: 10.1182/Blood-2017-05-786590  0.64
2017 Clinkenbeard EL, Hanudel MR, Stayrook KR, Appaiah HN, Farrow EG, Cass TA, Summers LJ, Ip CS, Hum JM, Thomas JC, Ivan M, Richine BM, Chan RJ, Clemens TL, Schipani E, ... ... Ganz T, et al. Erythropoietin stimulates murine and human Fibroblast growth factor-23, revealing novel roles for bone and bone marrow. Haematologica. PMID 28818868 DOI: 10.3324/Haematol.2017.167882  0.64
2017 McLachlan S, Page KE, Lee SM, Loguinov A, Valore E, Hui ST, Jung G, Zhou J, Lusis AJ, Fuqua B, Ganz T, Nemeth E, Vulpe CD. Hamp1 mRNA and plasma hepcidin levels are influenced by sex and strain but don't predict tissue iron levels in inbred mice. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00307.2016. PMID 28798083 DOI: 10.1152/Ajpgi.00307.2016  0.64
2017 Ganz T, Jung G, Naeim A, Ginzburg Y, Pakbaz Z, Walter PB, Kautz L, Nemeth E. Immunoassay for human serum erythroferrone. Blood. PMID 28739636 DOI: 10.1182/Blood-2017-04-777987  0.64
2017 Stefanova D, Raychev A, Arezes J, Ruchala P, Gabayan V, Skurnik M, Dillon BJ, Horwitz MA, Ganz T, Bulut Y, Nemeth E. Endogenous hepcidin and its agonist mediate resistance to selected infections by clearing non-transferrin-bound iron. Blood. PMID 28465342 DOI: 10.1182/Blood-2017-03-772715  0.64
2017 Khorramian E, Fung E, Chua K, Gabayan V, Ganz T, Nemeth E, Kim A. In a Mouse Model of Sepsis, Hepcidin Ablation Ameliorates Anemia More Effectively Than Iron and Erythropoietin Treatment. Shock (Augusta, Ga.). PMID 28452907 DOI: 10.1097/Shk.0000000000000886  0.64
2017 Michels KR, Zhang Z, Bettina AM, Cagnina RE, Stefanova D, Burdick MD, Vaulont S, Nemeth E, Ganz T, Mehrad B. Hepcidin-mediated iron sequestration protects against bacterial dissemination during pneumonia. Jci Insight. 2: e92002. PMID 28352667 DOI: 10.1172/Jci.Insight.92002  0.64
2017 Preziosi ME, Singh S, Valore EV, Jung CL, Popovic B, Poddar M, Nagarajan S, Ganz T, Monga SP. Mice lacking liver-specific β-catenin develop steatohepatitis and fibrosis after iron overload. Journal of Hepatology. PMID 28341391 DOI: 10.1016/J.Jhep.2017.03.012  0.64
2017 Aschemeyer S, Gabayan V, Ganz T, Nemeth E, Kautz L. Erythroferrone and matriptase-2 independently regulate hepcidin expression. American Journal of Hematology. PMID 28187515 DOI: 10.1002/Ajh.24672  0.64
2016 Hanudel MR, Rappaport M, Gabayan V, Jung G, Salusky IB, Nemeth E, Ganz T, Zaritsky J. Increased serum hepcidin contributes to the anemia of chronic kidney disease in a murine model. Haematologica. PMID 27884972 DOI: 10.3324/Haematol.2016.150433  0.64
2016 Hanudel MR, Chua K, Rappaport M, Gabayan V, Valore E, Goltzman D, Ganz T, Nemeth E, Salusky IB. Effects of Dietary Iron Intake and Chronic Kidney Disease on Fibroblast Growth Factor 23 Metabolism in Wild Type and Hepcidin Knockout Mice. American Journal of Physiology. Renal Physiology. ajprenal.00281.2016. PMID 27733366 DOI: 10.1152/Ajprenal.00281.2016  0.64
2016 Latour C, Wlodarczyk MF, Jung G, Gineste A, Blanchard N, Ganz T, Roth MP, Coppin H, Kautz L. Erythroferrone contributes to hepcidin repression in a mouse model of malarial anemia. Haematologica. PMID 27658439 DOI: 10.3324/Haematol.2016.150227  0.4
2016 Ganz T, Nemeth E. Iron Balance and the Role of Hepcidin in Chronic Kidney Disease. Seminars in Nephrology. 36: 87-93. PMID 27236128 DOI: 10.1016/J.Semnephrol.2016.02.001  0.96
2016 Casu C, Oikonomidou PR, Chen H, Nandi V, Ginzburg Y, Prasad P, Fleming RE, Shah YM, Valore EV, Nemeth E, Ganz T, MacDonald B, Rivella S. Minihepcidin peptides as disease modifiers in mice affected by β-thalassemia and polycythemia vera. Blood. PMID 27154187 DOI: 10.1182/Blood-2015-10-676742  0.64
2016 Macdougall IC, Bircher AJ, Eckardt KU, Obrador GT, Pollock CA, Stenvinkel P, Swinkels DW, Wanner C, Weiss G, Chertow GM. Iron management in chronic kidney disease: conclusions from a "Kidney Disease: Improving Global Outcomes" (KDIGO) Controversies Conference. Kidney International. 89: 28-39. PMID 26759045 DOI: 10.1016/J.Kint.2015.10.002  0.64
2016 Kim A, Fung E, Parikh SG, Gabayan V, Nemeth E, Ganz T. Isocitrate treatment of acute anemia of inflammation in a mouse model. Blood Cells, Molecules & Diseases. 56: 31-6. PMID 26603720 DOI: 10.1016/J.Bcmd.2015.09.007  0.96
2015 Drakesmith H, Nemeth E, Ganz T. Ironing out Ferroportin. Cell Metabolism. 22: 777-87. PMID 26437604 DOI: 10.1016/J.Cmet.2015.09.006  0.96
2015 Michels K, Nemeth E, Ganz T, Mehrad B. Hepcidin and Host Defense against Infectious Diseases. Plos Pathogens. 11: e1004998. PMID 26291319 DOI: 10.1371/Journal.Ppat.1004998  0.64
2015 Kautz L, Jung G, Du X, Gabayan V, Chapman J, Nasoff M, Nemeth E, Ganz T. Erythroferrone contributes to hepcidin suppression and iron overload in a mouse model of β-thalassemia. Blood. PMID 26276665 DOI: 10.1182/Blood-2015-07-658419  0.96
2015 Ganz T, Nemeth E. Iron homeostasis in host defence and inflammation. Nature Reviews. Immunology. 15: 500-10. PMID 26160612 DOI: 10.1038/Nri3863  0.96
2015 Chua K, Fung E, Micewicz ED, Ganz T, Nemeth E, Ruchala P. Small cyclic agonists of iron regulatory hormone hepcidin. Bioorganic & Medicinal Chemistry Letters. PMID 25813158 DOI: 10.1016/J.Bmcl.2015.03.012  0.96
2015 Keel SB, Doty R, Liu L, Nemeth E, Cherian S, Ganz T, Abkowitz JL. Evidence that the expression of transferrin receptor 1 on erythroid marrow cells mediates hepcidin suppression in the liver. Experimental Hematology. 43: 469-478.e6. PMID 25782630 DOI: 10.1016/J.Exphem.2015.03.001  0.96
2015 Fung E, Chua K, Ganz T, Nemeth E, Ruchala P. Thiol-derivatized minihepcidins retain biological activity. Bioorganic & Medicinal Chemistry Letters. 25: 763-6. PMID 25599838 DOI: 10.1016/J.Bmcl.2014.12.094  0.96
2015 Arezes J, Jung G, Gabayan V, Valore E, Ruchala P, Gulig PA, Ganz T, Nemeth E, Bulut Y. Hepcidin-induced hypoferremia is a critical host defense mechanism against the siderophilic bacterium Vibrio vulnificus. Cell Host & Microbe. 17: 47-57. PMID 25590758 DOI: 10.1016/J.Chom.2014.12.001  0.96
2015 Ganz T. Hepcidin and the global burden of iron deficiency. Clinical Chemistry. 61: 577-8. PMID 25492087 DOI: 10.1373/Clinchem.2014.229179  0.96
2015 Gutschow P, Schmidt PJ, Han H, Ostland V, Bartnikas TB, Pettiglio MA, Herrera C, Butler JS, Nemeth E, Ganz T, Fleming MD, Westerman M. A competitive enzyme-linked immunosorbent assay specific for murine hepcidin-1: correlation with hepatic mRNA expression in established and novel models of dysregulated iron homeostasis. Haematologica. 100: 167-77. PMID 25425686 DOI: 10.3324/Haematol.2014.116723  0.64
2015 Shawki A, Ruwe TA, Mitchell C, Prakash S, Nemeth E, Ganz T, Mackenzie B. Ferroportin-mediated cellular iron efflux requires extracellular calcium The Faseb Journal. 29. DOI: 10.1096/Fasebj.29.1_Supplement.566.15  0.64
2014 Kautz L, Jung G, Nemeth E, Ganz T. Erythroferrone contributes to recovery from anemia of inflammation. Blood. 124: 2569-74. PMID 25193872 DOI: 10.1182/Blood-2014-06-584607  0.96
2014 Zhang S, Chen Y, Guo W, Yuan L, Zhang D, Xu Y, Nemeth E, Ganz T, Liu S. Disordered hepcidin-ferroportin signaling promotes breast cancer growth. Cellular Signalling. 26: 2539-50. PMID 25093806 DOI: 10.1016/J.Cellsig.2014.07.029  0.96
2014 Nemeth E, Ganz T. Anemia of inflammation. Hematology/Oncology Clinics of North America. 28: 671-81, vi. PMID 25064707 DOI: 10.1016/J.Hoc.2014.04.005  0.96
2014 Domenico ID, Nemeth E, Nelson JM, Phillips JD, Ajioka RS, Kay MS, Kushner JP, Ganz T, Ward DM, Kaplan J. Retraction notice to: The hepcidin-binding site on ferroportin is evolutionarily conserved. Cell Metabolism. 19: 1067-1067. PMID 25025111 DOI: 10.1016/J.Cmet.2014.05.010  0.64
2014 Kautz L, Jung G, Valore EV, Rivella S, Nemeth E, Ganz T. Identification of erythroferrone as an erythroid regulator of iron metabolism. Nature Genetics. 46: 678-84. PMID 24880340 DOI: 10.1038/Ng.2996  0.96
2014 Kim A, Rivera S, Shprung D, Limbrick D, Gabayan V, Nemeth E, Ganz T. Mouse models of anemia of cancer. Plos One. 9: e93283. PMID 24681760 DOI: 10.1371/Journal.Pone.0093283  0.96
2014 Rodriguez R, Jung CL, Gabayan V, Deng JC, Ganz T, Nemeth E, Bulut Y. Hepcidin induction by pathogens and pathogen-derived molecules is strongly dependent on interleukin-6. Infection and Immunity. 82: 745-52. PMID 24478088 DOI: 10.1128/Iai.00983-13  0.96
2014 Kim A, Fung E, Parikh SG, Valore EV, Gabayan V, Nemeth E, Ganz T. A mouse model of anemia of inflammation: complex pathogenesis with partial dependence on hepcidin. Blood. 123: 1129-36. PMID 24357728 DOI: 10.1182/Blood-2013-08-521419  0.96
2014 Mitchell CJ, Shawki A, Ganz T, Nemeth E, Mackenzie B. Functional properties of human ferroportin, a cellular iron exporter reactive also with cobalt and zinc. American Journal of Physiology. Cell Physiology. 306: C450-9. PMID 24304836 DOI: 10.1152/Ajpcell.00348.2013  0.96
2014 Latour C, Kautz L, Besson-Fournier C, Island ML, Canonne-Hergaux F, Loréal O, Ganz T, Coppin H, Roth MP. Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin. Hepatology (Baltimore, Md.). 59: 683-94. PMID 23907767 DOI: 10.1002/Hep.26648  0.4
2013 Kautz L, Gabayan V, Wang X, Wu J, Onwuzurike J, Jung G, Qiao B, Lusis AJ, Ganz T, Nemeth E. Testing the iron hypothesis in a mouse model of atherosclerosis. Cell Reports. 5: 1436-42. PMID 24316081 DOI: 10.1016/J.Celrep.2013.11.009  0.96
2013 Ganz T. Systemic iron homeostasis. Physiological Reviews. 93: 1721-41. PMID 24137020 DOI: 10.1152/Physrev.00008.2013  0.96
2013 McCranor BJ, Langdon JM, Prince OD, Femnou LK, Berger AE, Cheadle C, Civin CI, Kim A, Rivera S, Ganz T, Vaulont S, Xue QL, Walston JD, Roy CN. Investigation of the role of interleukin-6 and hepcidin antimicrobial peptide in the development of anemia with age. Haematologica. 98: 1633-40. PMID 23996485 DOI: 10.3324/Haematol.2013.087114  0.96
2013 Clark RJ, Preza GC, Tan CC, van Dijk JW, Fung E, Nemeth E, Ganz T, Craik DJ. Design, synthesis, and characterization of cyclic analogues of the iron regulatory peptide hormone hepcidin. Biopolymers. 100: 519-26. PMID 23897622 DOI: 10.1002/Bip.22350  0.64
2013 Ganz T. Preface: iron and cancer. Critical Reviews in Oncogenesis. 18: preceding 391. PMID 23879592 DOI: 10.1615/Critrevoncog.2013007770  0.96
2013 Preza GC, Pinon R, Ganz T, Nemeth E. Cellular catabolism of the iron-regulatory peptide hormone hepcidin. Plos One. 8: e58934. PMID 23536837 DOI: 10.1371/Journal.Pone.0058934  0.96
2013 Mast AE, Schlumpf KS, Wright DJ, Johnson B, Glynn SA, Busch MP, Olbina G, Westerman M, Nemeth E, Ganz T. Hepcidin level predicts hemoglobin concentration in individuals undergoing repeated phlebotomy. Haematologica. 98: 1324-30. PMID 23445875 DOI: 10.3324/Haematol.2012.070979  0.96
2013 Fung E, Sugianto P, Hsu J, Damoiseaux R, Ganz T, Nemeth E. High-throughput screening of small molecules identifies hepcidin antagonists. Molecular Pharmacology. 83: 681-90. PMID 23292796 DOI: 10.1124/Mol.112.083428  0.96
2012 Ganz T, Goff J, Klasing K, Nemeth E, Roth T. IOD in rhinos--immunity group report: report from the Immunity, Genetics and Toxicology Working Group of the International Workshop on Iron Overload Disorder in Browsing Rhinoceros (February 2011). Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians. 43: S117-9. PMID 23156715 DOI: 10.1638/1042-7260-43.3S.S117  0.96
2012 Ganz T, Nemeth E. Iron homeostasis and its disorders in mice and men: potential lessons for rhinos. Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians. 43: S19-26. PMID 23156702 DOI: 10.1638/2011-0158.1  0.96
2012 Ramos E, Ruchala P, Goodnough JB, Kautz L, Preza GC, Nemeth E, Ganz T. Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis. Blood. 120: 3829-36. PMID 22990014 DOI: 10.1182/Blood-2012-07-440743  0.96
2012 Qiao B, Sugianto P, Fung E, Del-Castillo-Rueda A, Moran-Jimenez MJ, Ganz T, Nemeth E. Hepcidin-induced endocytosis of ferroportin is dependent on ferroportin ubiquitination. Cell Metabolism. 15: 918-24. PMID 22682227 DOI: 10.1016/J.Cmet.2012.03.018  0.96
2012 Ross SL, Tran L, Winters A, Lee KJ, Plewa C, Foltz I, King C, Miranda LP, Allen J, Beckman H, Cooke KS, Moody G, Sasu BJ, Nemeth E, Ganz T, et al. Molecular mechanism of hepcidin-mediated ferroportin internalization requires ferroportin lysines, not tyrosines or JAK-STAT. Cell Metabolism. 15: 905-17. PMID 22682226 DOI: 10.1016/J.Cmet.2012.03.017  0.96
2012 Besson-Fournier C, Latour C, Kautz L, Bertrand J, Ganz T, Roth MP, Coppin H. Induction of activin B by inflammatory stimuli up-regulates expression of the iron-regulatory peptide hepcidin through Smad1/5/8 signaling. Blood. 120: 431-9. PMID 22611157 DOI: 10.1182/Blood-2012-02-411470  0.4
2012 Ravasi G, Pelucchi S, Trombini P, Mariani R, Tomosugi N, Modignani GL, Pozzi M, Nemeth E, Ganz T, Hayashi H, Barisani D, Piperno A. Hepcidin expression in iron overload diseases is variably modulated by circulating factors. Plos One. 7: e36425. PMID 22586470 DOI: 10.1371/Journal.Pone.0036425  0.96
2012 Ganz T, Nemeth E. Iron metabolism: interactions with normal and disordered erythropoiesis. Cold Spring Harbor Perspectives in Medicine. 2: a011668. PMID 22553501 DOI: 10.1101/Cshperspect.A011668  0.96
2012 Ganz T. Macrophages and systemic iron homeostasis. Journal of Innate Immunity. 4: 446-53. PMID 22441209 DOI: 10.1159/000336423  0.96
2012 Ganz T, Nemeth E. Hepcidin and iron homeostasis. Biochimica Et Biophysica Acta. 1823: 1434-43. PMID 22306005 DOI: 10.1016/J.Bbamcr.2012.01.014  0.96
2012 Goodnough JB, Ramos E, Nemeth E, Ganz T. Inhibition of hepcidin transcription by growth factors. Hepatology (Baltimore, Md.). 56: 291-9. PMID 22278715 DOI: 10.1002/Hep.25615  0.96
2012 McMurray JJV, Parfrey PS, Adamson JW, Aljama P, Berns JS, Bohlius J, Drüeke TB, Finkelstein FO, Fishbane S, Ganz T, MacDougall IC, McDonald RA, McMahon LP, Obrador GT, Strippoli GFM, et al. Kidney disease: Improving global outcomes (KDIGO) anemia work group. KDIGO clinical practice guideline for anemia in chronic kidney disease Kidney International Supplements. 2: 279-335. DOI: 10.1038/Kisup.2012.37  0.96
2011 Ganz T, Nemeth E. The hepcidin-ferroportin system as a therapeutic target in anemias and iron overload disorders. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 2011: 538-42. PMID 22160086 DOI: 10.1182/Asheducation-2011.1.538  0.96
2011 Preza GC, Ruchala P, Pinon R, Ramos E, Qiao B, Peralta MA, Sharma S, Waring A, Ganz T, Nemeth E. Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload. The Journal of Clinical Investigation. 121: 4880-8. PMID 22045566 DOI: 10.1172/Jci57693  0.96
2011 Gordeuk VR, Miasnikova GY, Sergueeva AI, Niu X, Nouraie M, Okhotin DJ, Polyakova LA, Ammosova T, Nekhai S, Ganz T, Prchal JT. Chuvash polycythemia VHLR200W mutation is associated with down-regulation of hepcidin expression. Blood. 118: 5278-82. PMID 21876117 DOI: 10.1182/Blood-2011-03-345512  0.96
2011 Trombini P, Paolini V, Pelucchi S, Mariani R, Nemeth E, Ganz T, Piperno A. Hepcidin response to acute iron intake and chronic iron loading in dysmetabolic iron overload syndrome. Liver International : Official Journal of the International Association For the Study of the Liver. 31: 994-1000. PMID 21733088 DOI: 10.1111/J.1478-3231.2011.02520.X  0.96
2011 Miasnikova GY, Sergueeva AI, Nouraie M, Niu X, Okhotin DJ, Polyakova LA, Ganz T, Prchal JT, Gordeuk VR. The heterozygote advantage of the Chuvash polycythemia VHLR200W mutation may be protection against anemia. Haematologica. 96: 1371-4. PMID 21606165 DOI: 10.3324/Haematol.2011.045609  0.96
2011 Pasricha SR, McQuilten Z, Westerman M, Keller A, Nemeth E, Ganz T, Wood E. Serum hepcidin as a diagnostic test of iron deficiency in premenopausal female blood donors. Haematologica. 96: 1099-105. PMID 21508121 DOI: 10.3324/Haematol.2010.037960  0.96
2011 Ramos E, Kautz L, Rodriguez R, Hansen M, Gabayan V, Ginzburg Y, Roth MP, Nemeth E, Ganz T. Evidence for distinct pathways of hepcidin regulation by acute and chronic iron loading in mice. Hepatology (Baltimore, Md.). 53: 1333-41. PMID 21480335 DOI: 10.1002/Hep.24178  0.96
2011 Clark RJ, Tan CC, Preza GC, Nemeth E, Ganz T, Craik DJ. Understanding the structure/activity relationships of the iron regulatory peptide hepcidin. Chemistry & Biology. 18: 336-43. PMID 21439478 DOI: 10.1002/Psc.2448  0.96
2011 Ganz T. Hepcidin and iron regulation, 10 years later. Blood. 117: 4425-33. PMID 21346250 DOI: 10.1182/Blood-2011-01-258467  0.96
2011 Girelli D, Trombini P, Busti F, Campostrini N, Sandri M, Pelucchi S, Westerman M, Ganz T, Nemeth E, Piperno A, Camaschella C. A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis. Haematologica. 96: 500-6. PMID 21173098 DOI: 10.3324/Haematol.2010.033449  0.96
2011 Piperno A, Galimberti S, Mariani R, Pelucchi S, Ravasi G, Lombardi C, Bilo G, Revera M, Giuliano A, Faini A, Mainini V, Westerman M, Ganz T, Valsecchi MG, Mancia G, et al. Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: data from the HIGHCARE project. Blood. 117: 2953-9. PMID 21149632 DOI: 10.1182/Blood-2010-08-299859  0.96
2011 Ganz T, Nemeth E. Hepcidin and disorders of iron metabolism. Annual Review of Medicine. 62: 347-60. PMID 20887198 DOI: 10.1146/Annurev-Med-050109-142444  0.96
2010 Goodnough LT, Nemeth E, Ganz T. Detection, evaluation, and management of iron-restricted erythropoiesis. Blood. 116: 4754-61. PMID 20826717 DOI: 10.1182/Blood-2010-05-286260  0.96
2010 Maes K, Nemeth E, Roodman GD, Huston A, Esteve F, Freytes C, Callander N, Katodritou E, Tussing-Humphreys L, Rivera S, Vanderkerken K, Lichtenstein A, Ganz T. In anemia of multiple myeloma, hepcidin is induced by increased bone morphogenetic protein 2. Blood. 116: 3635-44. PMID 20679527 DOI: 10.1182/Blood-2010-03-274571  0.96
2010 Ayoya MA, Spiekermann-Brouwer GM, Stoltzfus RJ, Nemeth E, Habicht JP, Ganz T, Rawat R, Traoré AK, Garza C. Alpha 1-acid glycoprotein, hepcidin, C-reactive protein, and serum ferritin are correlated in anemic schoolchildren with Schistosoma haematobium. The American Journal of Clinical Nutrition. 91: 1784-90. PMID 20410090 DOI: 10.3945/Ajcn.2010.29353  0.96
2010 Zaritsky J, Young B, Gales B, Wang HJ, Rastogi A, Westerman M, Nemeth E, Ganz T, Salusky IB. Reduction of serum hepcidin by hemodialysis in pediatric and adult patients. Clinical Journal of the American Society of Nephrology : Cjasn. 5: 1010-4. PMID 20299375 DOI: 10.2215/Cjn.08161109  0.96
2010 Bdeir K, Higazi AA, Kulikovskaya I, Christofidou-Solomidou M, Vinogradov SA, Allen TC, Idell S, Linzmeier R, Ganz T, Cines DB. Neutrophil alpha-defensins cause lung injury by disrupting the capillary-epithelial barrier. American Journal of Respiratory and Critical Care Medicine. 181: 935-46. PMID 20093642 DOI: 10.1164/Rccm.200907-1128Oc  0.96
2010 Ferrucci L, Semba RD, Guralnik JM, Ershler WB, Bandinelli S, Patel KV, Sun K, Woodman RC, Andrews NC, Cotter RJ, Ganz T, Nemeth E, Longo DL. Proinflammatory state, hepcidin, and anemia in older persons. Blood. 115: 3810-6. PMID 20081092 DOI: 10.1182/Blood-2009-02-201087  0.96
2010 Westerman ME, Olbina G, Ostland VE, Nemeth E, Ganz T. Hepcidin: An emerging biomarker for iron disorders, inflammatory diseases, and infections Proceedings of Spie - the International Society For Optical Engineering. 7666. DOI: 10.1117/12.854910  0.96
2010 Piperno A, Pelucchi S, Mariani R, Nemeth E, Ganz T, Mainini V, Bilo G, Revera M, Savia G, Giuliano A, Faini A, Agostoni P, Mancia G, Parati G. The Iron-Hypoxia Link: Hepcidin Has A Central Role In The Response To Acute And Chronic Exposure To Hypobaric Hypoxia. Data From The Highcare Project: Pp.12.453 Journal of Hypertension. 28. DOI: 10.1097/01.Hjh.0000378778.87121.6B  0.64
2010 Andrews NC, Ganz T. The Molecular Basis of Iron Metabolism Molecular Hematology: Third Edition. 169-178. DOI: 10.1002/9781444318531.ch14  0.96
2010 Ganz T. Anemia of Chronic Disease Molecular Hematology: Third Edition. 165-168. DOI: 10.1002/9781444318531.ch13  0.96
2009 Kroot JJ, Kemna EH, Bansal SS, Busbridge M, Campostrini N, Girelli D, Hider RC, Koliaraki V, Mamalaki A, Olbina G, Tomosugi N, Tselepis C, Ward DG, Ganz T, Hendriks JC, et al. Results of the first international round robin for the quantification of urinary and plasma hepcidin assays: need for standardization. Haematologica. 94: 1748-52. PMID 19996119 DOI: 10.3324/Haematol.2009.010322  0.96
2009 Nemeth E, Ganz T. The role of hepcidin in iron metabolism. Acta Haematologica. 122: 78-86. PMID 19907144 DOI: 10.1159/000243791  0.96
2009 Ganz T, Nemeth E. Iron sequestration and anemia of inflammation. Seminars in Hematology. 46: 387-93. PMID 19786207 DOI: 10.1053/J.Seminhematol.2009.06.001  0.96
2009 Rivera S, Ganz T. Animal models of anemia of inflammation. Seminars in Hematology. 46: 351-7. PMID 19786203 DOI: 10.1053/J.Seminhematol.2009.06.003  0.96
2009 Girelli D, Pasino M, Goodnough JB, Nemeth E, Guido M, Castagna A, Busti F, Campostrini N, Martinelli N, Vantini I, Corrocher R, Ganz T, Fattovich G. Reduced serum hepcidin levels in patients with chronic hepatitis C. Journal of Hepatology. 51: 845-52. PMID 19729219 DOI: 10.1016/J.Jhep.2009.06.027  0.96
2009 Sham RL, Phatak PD, Nemeth E, Ganz T. Hereditary hemochromatosis due to resistance to hepcidin: high hepcidin concentrations in a family with C326S ferroportin mutation. Blood. 114: 493-4. PMID 19589941 DOI: 10.1182/Blood-2009-04-216226  0.96
2009 Tanno T, Porayette P, Sripichai O, Noh SJ, Byrnes C, Bhupatiraju A, Lee YT, Goodnough JB, Harandi O, Ganz T, Paulson RF, Miller JL. Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells. Blood. 114: 181-6. PMID 19414861 DOI: 10.1182/Blood-2008-12-195503  0.96
2009 Zaritsky J, Young B, Wang HJ, Westerman M, Olbina G, Nemeth E, Ganz T, Rivera S, Nissenson AR, Salusky IB. Hepcidin--a potential novel biomarker for iron status in chronic kidney disease. Clinical Journal of the American Society of Nephrology : Cjasn. 4: 1051-6. PMID 19406957 DOI: 10.2215/Cjn.05931108  0.96
2009 Ruivard M, Lainé F, Ganz T, Olbina G, Westerman M, Nemeth E, Rambeau M, Mazur A, Gerbaud L, Tournilhac V, Abergel A, Philippe P, Deugnier Y, Coudray C. Iron absorption in dysmetabolic iron overload syndrome is decreased and correlates with increased plasma hepcidin. Journal of Hepatology. 50: 1219-25. PMID 19398238 DOI: 10.1016/J.Jhep.2009.01.029  0.96
2009 Fernandes A, Preza GC, Phung Y, De Domenico I, Kaplan J, Ganz T, Nemeth E. The molecular basis of hepcidin-resistant hereditary hemochromatosis. Blood. 114: 437-43. PMID 19383972 DOI: 10.1182/Blood-2008-03-146134  0.96
2009 Troadec MB, Lainé F, Daniel V, Rochcongar P, Ropert M, Cabillic F, Perrin M, Morcet J, Loréal O, Olbina G, Westerman M, Nemeth E, Ganz T, Brissot P. Daily regulation of serum and urinary hepcidin is not influenced by submaximal cycling exercise in humans with normal iron metabolism. European Journal of Applied Physiology. 106: 435-43. PMID 19306018 DOI: 10.1007/S00421-009-1031-8  0.96
2009 Ganz T. Iron in innate immunity: starve the invaders. Current Opinion in Immunology. 21: 63-7. PMID 19231148 DOI: 10.1016/J.Coi.2009.01.011  0.96
2009 Wilson CL, Schmidt AP, Pirilä E, Valore EV, Ferri N, Sorsa T, Ganz T, Parks WC. Differential Processing of {alpha}- and {beta}-Defensin Precursors by Matrix Metalloproteinase-7 (MMP-7). The Journal of Biological Chemistry. 284: 8301-11. PMID 19181662 DOI: 10.1074/Jbc.M809744200  0.96
2008 Ganz T, Olbina G, Girelli D, Nemeth E, Westerman M. Immunoassay for human serum hepcidin. Blood. 112: 4292-7. PMID 18689548 DOI: 10.1182/Blood-2008-02-139915  0.96
2008 De Domenico I, Nemeth E, Nelson JM, Phillips JD, Ajioka RS, Kay MS, Kushner JP, Ganz T, Ward DM, Kaplan J. The hepcidin-binding site on ferroportin is evolutionarily conserved. Cell Metabolism. 8: 146-56. PMID 18680715 DOI: 10.1016/J.Cmet.2008.07.002  0.96
2008 Sharma S, Nemeth E, Chen YH, Goodnough J, Huston A, Roodman GD, Ganz T, Lichtenstein A. Involvement of hepcidin in the anemia of multiple myeloma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3262-7. PMID 18519751 DOI: 10.1158/1078-0432.Ccr-07-4153  0.96
2008 Winder A, Lefkowitz R, Ghoti H, Leiba M, Ganz T, Nemeth E, Rachmilewitz EA. Urinary hepcidin excretion in patients with myelodysplastic syndrome and myelofibrosis. British Journal of Haematology. 142: 669-71. PMID 18498424 DOI: 10.1111/J.1365-2141.2008.07225.X  0.96
2008 Barisani D, Pelucchi S, Mariani R, Galimberti S, Trombini P, Fumagalli D, Meneveri R, Nemeth E, Ganz T, Piperno A. Hepcidin and iron-related gene expression in subjects with Dysmetabolic Hepatic Iron Overload. Journal of Hepatology. 49: 123-33. PMID 18462824 DOI: 10.1016/J.Jhep.2008.03.011  0.96
2008 Ganz T. Iron homeostasis: fitting the puzzle pieces together. Cell Metabolism. 7: 288-90. PMID 18396134 DOI: 10.1016/J.Cmet.2008.03.008  0.96
2008 Bozzini C, Campostrini N, Trombini P, Nemeth E, Castagna A, Tenuti I, Corrocher R, Camaschella C, Ganz T, Olivieri O, Piperno A, Girelli D. Measurement of urinary hepcidin levels by SELDI-TOF-MS in HFE-hemochromatosis. Blood Cells, Molecules & Diseases. 40: 347-52. PMID 18164223 DOI: 10.1182/Blood.V110.11.2668.2668  0.96
2008 Aberg KM, Man MQ, Gallo RL, Ganz T, Crumrine D, Brown BE, Choi EH, Kim DK, Schröder JM, Feingold KR, Elias PM. Co-regulation and interdependence of the mammalian epidermal permeability and antimicrobial barriers. The Journal of Investigative Dermatology. 128: 917-25. PMID 17943185 DOI: 10.1038/Sj.Jid.5701099  0.96
2008 Valore EV, Ganz T. Posttranslational processing of hepcidin in human hepatocytes is mediated by the prohormone convertase furin. Blood Cells, Molecules & Diseases. 40: 132-8. PMID 17905609 DOI: 10.1016/J.Bcmd.2007.07.009  0.96
2008 Lin L, Nemeth E, Goodnough JB, Thapa DR, Gabayan V, Ganz T. Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site. Blood Cells, Molecules & Diseases. 40: 122-31. PMID 17869549 DOI: 10.1016/J.Bcmd.2007.06.023  0.96
2007 Aberg KM, Radek KA, Choi EH, Kim DK, Demerjian M, Hupe M, Kerbleski J, Gallo RL, Ganz T, Mauro T, Feingold KR, Elias PM. Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice. The Journal of Clinical Investigation. 117: 3339-49. PMID 17975669 DOI: 10.1172/Jci31726  0.96
2007 Trombini P, Coliva T, Nemeth E, Mariani R, Ganz T, Biondi A, Piperno A. Effects of plasma transfusion on hepcidin production in human congenital hypotransferrinemia. Haematologica. 92: 1407-10. PMID 17768112 DOI: 10.3324/Haematol.11377  0.96
2007 Piperno A, Girelli D, Nemeth E, Trombini P, Bozzini C, Poggiali E, Phung Y, Ganz T, Camaschella C. Blunted hepcidin response to oral iron challenge in HFE-related hemochromatosis. Blood. 110: 4096-100. PMID 17724144 DOI: 10.1182/Blood-2007-06-096503  0.96
2007 Lin L, Valore EV, Nemeth E, Goodnough JB, Gabayan V, Ganz T. Iron transferrin regulates hepcidin synthesis in primary hepatocyte culture through hemojuvelin and BMP2/4. Blood. 110: 2182-9. PMID 17540841 DOI: 10.1182/Blood-2007-04-087593  0.96
2007 Origa R, Galanello R, Ganz T, Giagu N, Maccioni L, Faa G, Nemeth E. Liver iron concentrations and urinary hepcidin in beta-thalassemia. Haematologica. 92: 583-8. PMID 17488680 DOI: 10.3324/Haematol.10842  0.96
2007 De Domenico I, Ward DM, Langelier C, Vaughn MB, Nemeth E, Sundquist WI, Ganz T, Musci G, Kaplan J. The molecular mechanism of hepcidin-mediated ferroportin down-regulation. Molecular Biology of the Cell. 18: 2569-78. PMID 17475779 DOI: 10.1091/Mbc.E07-01-0060  0.96
2007 Ganz T. Molecular control of iron transport. Journal of the American Society of Nephrology : Jasn. 18: 394-400. PMID 17229910 DOI: 10.1681/Asn.2006070802  0.96
2007 Kearney SL, Nemeth E, Neufeld EJ, Thapa D, Ganz T, Weinstein DA, Cunningham MJ. Urinary hepcidin in congenital chronic anemias. Pediatric Blood & Cancer. 48: 57-63. PMID 16220548 DOI: 10.1002/Pbc.20616  0.96
2007 Nemeth E, Ganz T. Iron and aging Blood Disorders in the Elderly. 171-180. DOI: 10.1017/CBO9780511545238.014  0.96
2006 Ganz T. Hepcidin and its role in regulating systemic iron metabolism. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 29-35, 507. PMID 17124036 DOI: 10.1182/Asheducation-2006.1.29  0.96
2006 Valore EV, Wiley DJ, Ganz T. Reversible deficiency of antimicrobial polypeptides in bacterial vaginosis. Infection and Immunity. 74: 5693-702. PMID 16988245 DOI: 10.1128/Iai.00524-06  0.96
2006 Ganz T. Hepcidin - A peptide hormone at the interface of innate immunity and iron metabolism Current Topics in Microbiology and Immunology. 306: 183-198. PMID 16909922 DOI: 10.1007/3-540-29916-5_7  0.96
2006 De Domenico I, McVey Ward D, Nemeth E, Ganz T, Corradini E, Ferrara F, Musci G, Pietrangelo A, Kaplan J. Molecular and clinical correlates in iron overload associated with mutations in ferroportin. Haematologica. 91: 1092-5. PMID 16885049  0.96
2006 Pak M, Lopez MA, Gabayan V, Ganz T, Rivera S. Suppression of hepcidin during anemia requires erythropoietic activity. Blood. 108: 3730-5. PMID 16882706 DOI: 10.1182/Blood-2006-06-028787  0.96
2006 Tan BH, Meinken C, Bastian M, Bruns H, Legaspi A, Ochoa MT, Krutzik SR, Bloom BR, Ganz T, Modlin RL, Stenger S. Macrophages acquire neutrophil granules for antimicrobial activity against intracellular pathogens. Journal of Immunology (Baltimore, Md. : 1950). 177: 1864-71. PMID 16849498 DOI: 10.4049/Jimmunol.177.3.1864  0.96
2006 Nemeth E, Ganz T. Regulation of iron metabolism by hepcidin. Annual Review of Nutrition. 26: 323-42. PMID 16848710 DOI: 10.1146/Annurev.Nutr.26.061505.111303  0.96
2006 Pospisilova D, Mims MP, Nemeth E, Ganz T, Prchal JT. DMT1 mutation: response of anemia to darbepoetin administration and implications for iron homeostasis. Blood. 108: 404-5. PMID 16790587 DOI: 10.1182/Blood-2006-02-003962  0.96
2006 Ganz T, Nemeth E. Regulation of iron acquisition and iron distribution in mammals. Biochimica Et Biophysica Acta. 1763: 690-9. PMID 16790283 DOI: 10.1016/J.Bbamcr.2006.03.014  0.96
2006 Sørensen OE, Thapa DR, Roupé KM, Valore EV, Sjöbring U, Roberts AA, Schmidtchen A, Ganz T. Injury-induced innate immune response in human skin mediated by transactivation of the epidermal growth factor receptor. The Journal of Clinical Investigation. 116: 1878-85. PMID 16778986 DOI: 10.1172/Jci28422  0.96
2006 Nemeth E, Ganz T. Hepcidin and iron-loading anemias. Haematologica. 91: 727-32. PMID 16769573  0.96
2006 Linzmeier RM, Ganz T. Copy number polymorphisms are not a common feature of innate immune genes. Genomics. 88: 122-6. PMID 16617005 DOI: 10.1016/J.Ygeno.2006.03.005  0.96
2006 Ganz T, Nemeth E. Iron imports. IV. Hepcidin and regulation of body iron metabolism. American Journal of Physiology. Gastrointestinal and Liver Physiology. 290: G199-203. PMID 16407589 DOI: 10.1152/Ajpgi.00412.2005  0.96
2006 Ganz T. Molecular pathogenesis of anemia of chronic disease. Pediatric Blood & Cancer. 46: 554-7. PMID 16261603 DOI: 10.1002/Pbc.20656  0.96
2006 Nemeth E, Preza GC, Jung CL, Kaplan J, Waring AJ, Ganz T. The N-terminus of hepcidin is essential for its interaction with ferroportin: structure-function study. Blood. 107: 328-33. PMID 16141345 DOI: 10.1182/Blood-2005-05-2049  0.96
2005 Wehkamp J, Salzman NH, Porter E, Nuding S, Weichenthal M, Petras RE, Shen B, Schaeffeler E, Schwab M, Linzmeier R, Feathers RW, Chu H, Lima H, Fellermann K, Ganz T, et al. Reduced Paneth cell alpha-defensins in ileal Crohn's disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 18129-34. PMID 16330776 DOI: 10.1073/Pnas.0505256102  0.96
2005 Roecker L, Meier-Buttermilch R, Brechtel L, Nemeth E, Ganz T. Iron-regulatory protein hepcidin is increased in female athletes after a marathon. European Journal of Applied Physiology. 95: 569-71. PMID 16249921 DOI: 10.1007/S00421-005-0055-Y  0.96
2005 Cole AM, Thapa DR, Gabayan V, Liao HI, Liu L, Ganz T. Decreased clearance of Pseudomonas aeruginosa from airways of mice deficient in lysozyme M. Journal of Leukocyte Biology. 78: 1081-5. PMID 16204648 DOI: 10.1189/Jlb.0205073  0.96
2005 Porto G, Roetto A, Daraio F, Pinto JP, Almeida S, Bacelar C, Nemeth E, Ganz T, Camaschella C. A Portuguese patient homozygous for the -25G>A mutation of the HAMP promoter shows evidence of steady-state transcription but fails to up-regulate hepcidin levels by iron. Blood. 106: 2922-3. PMID 16204153 DOI: 10.1182/Blood-2005-04-1630  0.64
2005 Ganz T. Cellular iron: ferroportin is the only way out. Cell Metabolism. 1: 155-7. PMID 16054057 DOI: 10.1016/J.Cmet.2005.02.005  0.96
2005 Porter E, Yang H, Yavagal S, Preza GC, Murillo O, Lima H, Greene S, Mahoozi L, Klein-Patel M, Diamond G, Gulati S, Ganz T, Rice PA, Quayle AJ. Distinct defensin profiles in Neisseria gonorrhoeae and Chlamydia trachomatis urethritis reveal novel epithelial cell-neutrophil interactions. Infection and Immunity. 73: 4823-33. PMID 16040996 DOI: 10.1128/Iai.73.8.4823-4833.2005  0.96
2005 Linzmeier RM, Ganz T. Human defensin gene copy number polymorphisms: comprehensive analysis of independent variation in alpha- and beta-defensin regions at 8p22-p23. Genomics. 86: 423-30. PMID 16039093 DOI: 10.1016/J.Ygeno.2005.06.003  0.96
2005 Lin L, Goldberg YP, Ganz T. Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin. Blood. 106: 2884-9. PMID 15998830 DOI: 10.1182/blood-2005-05-1845  0.96
2005 Zoller H, McFarlane I, Theurl I, Stadlmann S, Nemeth E, Oxley D, Ganz T, Halsall DJ, Cox TM, Vogel W. Primary iron overload with inappropriate hepcidin expression in V162del ferroportin disease. Hepatology (Baltimore, Md.). 42: 466-72. PMID 15986403 DOI: 10.1002/Hep.20775  0.96
2005 Shen B, Porter EM, Reynoso E, Shen C, Ghosh D, Connor JT, Drazba J, Rho HK, Gramlich TL, Li R, Ormsby AH, Sy MS, Ganz T, Bevins CL. Human defensin 5 expression in intestinal metaplasia of the upper gastrointestinal tract. Journal of Clinical Pathology. 58: 687-94. PMID 15976333 DOI: 10.1136/Jcp.2004.022426  0.96
2005 De Domenico I, Ward DM, Nemeth E, Vaughn MB, Musci G, Ganz T, Kaplan J. The molecular basis of ferroportin-linked hemochromatosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 8955-60. PMID 15956209 DOI: 10.1073/Pnas.0503804102  0.96
2005 Rivera S, Nemeth E, Gabayan V, Lopez MA, Farshidi D, Ganz T. Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs. Blood. 106: 2196-9. PMID 15933050 DOI: 10.1182/Blood-2005-04-1766  0.96
2005 Ganz T. Defensins and other antimicrobial peptides: a historical perspective and an update. Combinatorial Chemistry & High Throughput Screening. 8: 209-17. PMID 15892623 DOI: 10.2174/1386207053764594  0.96
2005 Miller LS, Sørensen OE, Liu PT, Jalian HR, Eshtiaghpour D, Behmanesh BE, Chung W, Starner TD, Kim J, Sieling PA, Ganz T, Modlin RL. TGF-alpha regulates TLR expression and function on epidermal keratinocytes. Journal of Immunology (Baltimore, Md. : 1950). 174: 6137-43. PMID 15879109 DOI: 10.4049/Jimmunol.174.10.6137  0.96
2005 Liuzzi JP, Lichten LA, Rivera S, Blanchard RK, Aydemir TB, Knutson MD, Ganz T, Cousins RJ. Interleukin-6 regulates the zinc transporter Zip14 in liver and contributes to the hypozincemia of the acute-phase response. Proceedings of the National Academy of Sciences of the United States of America. 102: 6843-8. PMID 15863613 DOI: 10.1073/Pnas.0502257102  0.96
2005 Sørensen OE, Thapa DR, Rosenthal A, Liu L, Roberts AA, Ganz T. Differential regulation of beta-defensin expression in human skin by microbial stimuli. Journal of Immunology (Baltimore, Md. : 1950). 174: 4870-9. PMID 15814714 DOI: 10.4049/Jimmunol.174.8.4870  0.96
2005 Détivaud L, Nemeth E, Boudjema K, Turlin B, Troadec MB, Leroyer P, Ropert M, Jacquelinet S, Courselaud B, Ganz T, Brissot P, Loréal O. Hepcidin levels in humans are correlated with hepatic iron stores, hemoglobin levels, and hepatic function. Blood. 106: 746-8. PMID 15797999 DOI: 10.1182/Blood-2004-12-4855  0.64
2005 Ganz T. Hepcidin - A regular of intestinal iron absorption and iron recycling by macrophages Best Practice and Research: Clinical Haematology. 18: 171-182. PMID 15737883 DOI: 10.1016/J.Beha.2004.08.020  0.96
2005 Papanikolaou G, Tzilianos M, Christakis JI, Bogdanos D, Tsimirika K, MacFarlane J, Goldberg YP, Sakellaropoulos N, Ganz T, Nemeth E. Hepcidin in iron overload disorders. Blood. 105: 4103-5. PMID 15671438 DOI: 10.1182/Blood-2004-12-4844  0.64
2005 Nemeth E, Roetto A, Garozzo G, Ganz T, Camaschella C. Hepcidin is decreased in TFR2 hemochromatosis. Blood. 105: 1803-6. PMID 15486069 DOI: 10.1182/Blood-2004-08-3042  0.96
2005 Rivera S, Liu L, Nemeth E, Gabayan V, Sorensen OE, Ganz T. Hepcidin excess induces the sequestration of iron and exacerbates tumor-associated anemia. Blood. 105: 1797-802. PMID 15479721 DOI: 10.1182/Blood-2004-08-3375  0.96
2005 Lehrer RI, Bevins CL, Ganz T. Defensins and other antimicrobial peptides and proteins Mucosal Immunology, Two-Volume Set. 95-110. DOI: 10.1016/B978-012491543-5/50010-3  0.96
2004 Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, Kaplan J. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science (New York, N.Y.). 306: 2090-3. PMID 15514116 DOI: 10.1126/Science.1104742  0.96
2004 Ross DJ, Cole AM, Yoshioka D, Park AK, Belperio JA, Laks H, Strieter RM, Lynch JP, Kubak B, Ardehali A, Ganz T. Increased bronchoalveolar lavage human beta-defensin type 2 in bronchiolitis obliterans syndrome after lung transplantation. Transplantation. 78: 1222-4. PMID 15502724 DOI: 10.1097/01.Tp.0000137265.18491.75  0.96
2004 Kalfa VC, Spector SL, Ganz T, Cole AM. Lysozyme levels in the nasal secretions of patients with perennial allergic rhinitis and recurrent sinusitis Annals of Allergy, Asthma and Immunology. 93: 288-292. PMID 15478391 DOI: 10.1016/S1081-1206(10)61503-7  0.96
2004 Ganz T. Defensins: Antimicrobial peptides of vertebrates Comptes Rendus - Biologies. 327: 539-549. PMID 15330253 DOI: 10.1016/J.Crvi.2003.12.007  0.96
2004 Ganz T. Hepcidin in iron metabolism Current Opinion in Hematology. 11: 251-254. PMID 15314524 DOI: 10.1097/00062752-200407000-00004  0.96
2004 Nemeth E, Rivera S, Gabayan V, Keller C, Taudorf S, Pedersen BK, Ganz T. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. The Journal of Clinical Investigation. 113: 1271-6. PMID 15124018 DOI: 10.1172/Jci20945  0.96
2004 Papanikolaou G, Samuels ME, Ludwig EH, MacDonald ML, Franchini PL, Dubé MP, Andres L, MacFarlane J, Sakellaropoulos N, Politou M, Nemeth E, Thompson J, Risler JK, Zaborowska C, Babakaiff R, ... ... Ganz T, et al. Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. Nature Genetics. 36: 77-82. PMID 14647275 DOI: 10.1038/Ng1274  0.96
2004 Ganz T. Is TfR2 the iron sensor? Blood. 104: 3839-3840. DOI: 10.1182/Blood-2004-09-3664  0.96
2003 Hertz CJ, Wu Q, Porter EM, Zhang YJ, Weismüller KH, Godowski PJ, Ganz T, Randell SH, Modlin RL. Activation of Toll-like receptor 2 on human tracheobronchial epithelial cells induces the antimicrobial peptide human beta defensin-2. Journal of Immunology (Baltimore, Md. : 1950). 171: 6820-6. PMID 14662888 DOI: 10.4049/Jimmunol.171.12.6820  0.96
2003 Ganz T. Defensins: Antimicrobial peptides of innate immunity Nature Reviews Immunology. 3: 710-720. PMID 12949495 DOI: 10.1038/Nri1180  0.96
2003 Milner SM, Cole A, Ortega MR, Bakir MH, Gulati S, Bhat S, Ganz T. Inducibility of HBD-2 in acute burns and chronic conditions of the lung. Burns : Journal of the International Society For Burn Injuries. 29: 553-5. PMID 12927979 DOI: 10.1016/S0305-4179(03)00145-1  0.96
2003 Oren A, Ganz T, Liu L, Meerloo T. In human epidermis, β-defensin 2 is packaged in lamellar bodies Experimental and Molecular Pathology. 74: 180-182. PMID 12710950 DOI: 10.1016/S0014-4800(02)00023-0  0.96
2003 Ganz T. Gut defence Nature. 422: 478-479. PMID 12673233 DOI: 10.1038/422478A  0.96
2003 Ganz T. Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation Blood. 102: 783-788. PMID 12663437 DOI: 10.1182/Blood-2003-03-0672  0.96
2003 Ganz T. Angiogenin: An antimicrobial ribonuclease Nature Immunology. 4: 213-214. PMID 12605229 DOI: 10.1038/Ni0303-213  0.96
2003 Cole AM, Liao HI, Ganz T, Yang OO, Klenk HD. Antibacterial activity of peptides derived from envelope glycoproteins of HIV-1 Febs Letters. 535: 195-199. PMID 12560103 DOI: 10.1016/S0014-5793(02)03860-7  0.96
2003 Liu L, Roberts AA, Ganz T. By IL-1 signaling, monocyte-derived cells dramatically enhance the epidermal antimicrobial response to lipopolysaccharide. Journal of Immunology (Baltimore, Md. : 1950). 170: 575-80. PMID 12496445 DOI: 10.4049/Jimmunol.170.1.575  0.96
2003 Nemeth E, Valore EV, Territo M, Schiller G, Lichtenstein A, Ganz T. Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood. 101: 2461-3. PMID 12433676 DOI: 10.1182/Blood-2002-10-3235  0.64
2003 Ganz T, Gabayan V, Liao HI, Liu L, Oren A, Graf T, Cole AM. Increased inflammation in lysozyme M-deficient mice in response to Micrococcus luteus and its peptidoglycan Blood. 101: 2388-2392. PMID 12411294 DOI: 10.1182/Blood-2002-07-2319  0.96
2003 Ganz T. The role of antimicrobial peptides in innate immunity Integrative and Comparative Biology. 43: 300-304. DOI: 10.1093/Icb/43.2.300  0.96
2002 Huang GT, Zhang HB, Kim D, Liu L, Ganz T. A model for antimicrobial gene therapy: demonstration of human beta-defensin 2 antimicrobial activities in vivo. Human Gene Therapy. 13: 2017-25. PMID 12489997 DOI: 10.1089/10430340260395875  0.96
2002 Ganz T. The role of hepcidin in iron sequestration during infections and in the pathogenesis of anemia of chronic disease The Israel Medical Association Journal : Imaj. 4: 1043-1045. PMID 12489503  0.96
2002 Cole AM, Liao HI, Stuchlik O, Tilan J, Pohl J, Ganz T. Cationic polypeptides are required for antibacterial activity of human airway fluid Journal of Immunology. 169: 6985-6991. PMID 12471133 DOI: 10.4049/Jimmunol.169.12.6985  0.96
2002 Ganz T. Immunology: Versatile defensins Science. 298: 977-979. PMID 12411693 DOI: 10.1126/Science.1078708  0.96
2002 Valore EV, Park CH, Igreti SL, Ganz T. Antimicrobial components of vaginal fluid American Journal of Obstetrics and Gynecology. 187: 561-568. PMID 12237628 DOI: 10.1067/Mob.2002.125280  0.96
2002 Hunter HN, Fulton DB, Ganz T, Vogel HJ. The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis. The Journal of Biological Chemistry. 277: 37597-603. PMID 12138110 DOI: 10.1074/Jbc.M205305200  0.96
2002 Hein M, Valore EV, Helmig RB, Uldbjerg N, Ganz T. Antimicrobial factors in the cervical mucus plug American Journal of Obstetrics and Gynecology. 187: 137-144. PMID 12114901 DOI: 10.1067/Mob.2002.123034  0.96
2002 Levy O, Sisson RB, Fryer HE, Goldmann D, Valore E, Ganz T, White ML, Carroll SF, Lehmann L, Guinan EC. Neutrophil defense in patients undergoing bone marrow transplantation: bactericidal/permeability-increasing protein (BPI) and defensins in graft-derived neutrophils. Transplantation. 73: 1522-6. PMID 12023636 DOI: 10.1097/00007890-200205150-00027  0.96
2002 Ghosh D, Porter E, Shen B, Lee SK, Wilk D, Drazba J, Yadav SP, Crabb JW, Ganz T, Bevins CL. Paneth cell trypsin is the processing enzyme for human defensin-5. Nature Immunology. 3: 583-90. PMID 12021776 DOI: 10.1038/Ni797  0.96
2002 Cole AM, Ganz T. Antimicrobial peptides and proteins in the CF airway Methods in Molecular Medicine. 70: 447-464. PMID 11917542 DOI: 10.1385/1-59259-187-6:447  0.96
2002 Ganz T. Epithelia: Not just physical barriers Proceedings of the National Academy of Sciences of the United States of America. 99: 3357-3358. PMID 11904396 DOI: 10.1073/Pnas.072073199  0.96
2002 Ganz T. Antimicrobial polypeptides in host defense of the respiratory tract Journal of Clinical Investigation. 109: 693-697. PMID 11901174 DOI: 10.1172/Jci15218  0.96
2002 Henneman E, Dracup K, Ganz T, Molayeme O, Cooper CB. Using a collaborative weaning plan to decrease duration of mechanical ventilation and length of stay in the intensive care unit for patients receiving long-term ventilation. American Journal of Critical Care : An Official Publication, American Association of Critical-Care Nurses. 11: 132-40. PMID 11888125  0.96
2002 Porter EM, Bevins CL, Ghosh D, Ganz T. The multifaceted Paneth cell Cellular and Molecular Life Sciences. 59: 156-170. PMID 11846026 DOI: 10.1007/S00018-002-8412-Z  0.96
2002 Liu AY, Destoumieux D, Wong AV, Park CH, Valore EV, Liu L, Ganz T. Human beta-defensin-2 production in keratinocytes is regulated by interleukin-1, bacteria, and the state of differentiation. The Journal of Investigative Dermatology. 118: 275-81. PMID 11841544 DOI: 10.1046/J.0022-202X.2001.01651.X  0.64
2002 Lehrer RI, Ganz T. Defensins of vertebrate animals Current Opinion in Immunology. 14: 96-102. PMID 11790538 DOI: 10.1016/S0952-7915(01)00303-X  0.96
2002 Lehrer RI, Ganz T. Cathelicidins: A family of endogenous antimicrobial peptides Current Opinion in Hematology. 9: 18-22. PMID 11753073 DOI: 10.1097/00062752-200201000-00004  0.96
2001 Cole AM, Tahk S, Oren A, Yoshioka D, Kim YH, Park A, Ganz T. Determinants of Staphylococcus aureus nasal carriage Clinical and Diagnostic Laboratory Immunology. 8: 1064-1069. PMID 11687441 DOI: 10.1128/Cdli.8.6.1064-1069.2001  0.96
2001 Dale BA, Kimball JR, Krisanaprakornkit S, Roberts F, Robinovitch M, O'Neal R, Valore EV, Ganz T, Anderson GM, Weinberg A. Localized antimicrobial peptide expression in human gingiva. Journal of Periodontal Research. 36: 285-94. PMID 11585115 DOI: 10.1034/J.1600-0765.2001.360503.X  0.96
2001 Hein M, Helmig RB, Schønheyder HC, Ganz T, Uldbjerg N. An in vitro study of antibacterial properties of the cervical mucus plug in pregnancy American Journal of Obstetrics and Gynecology. 185: 586-592. PMID 11568782 DOI: 10.1067/Mob.2001.116685  0.96
2001 Cole AM, Kim YH, Tahk S, Hong T, Weis P, Waring AJ, Ganz T. Calcitermin, a novel antimicrobial peptide isolated from human airway secretions Febs Letters. 504: 5-10. PMID 11522286 DOI: 10.1016/S0014-5793(01)02731-4  0.96
2001 Diamond DL, Kimball JR, Krisanaprakornkit S, Ganz T, Dale BA. Detection of β-defensins secreted by human oral epithelial cells Journal of Immunological Methods. 256: 65-76. PMID 11516756 DOI: 10.1016/S0022-1759(01)00442-2  0.96
2001 Ganz T. Chemistry: Rings of destruction Nature. 412: 392-393. PMID 11473296 DOI: 10.1038/35086680  0.96
2001 Cole AM, Ganz T, Liese AM, Burdick MD, Liu L, Strieter RM. Cutting edge: IFN-inducible ELR- CXC chemokines display defensin-like antimicrobial activity Journal of Immunology. 167: 623-627. PMID 11441062 DOI: 10.4049/Jimmunol.167.2.623  0.96
2001 Ganz T. Fatal attraction evaded: How pathogenic bacteria resist cationic polypeptides Journal of Experimental Medicine. 193. PMID 11342596 DOI: 10.1084/Jem.193.9.F31  0.96
2001 Ganz T. Antimicrobial proteins and peptides in host defense Seminars in Respiratory Infections. 16: 4-10. PMID 11309707 DOI: 10.1053/Srin.2001.22723  0.96
2001 Sawai MV, Jia HP, Liu L, Aseyev V, Wiencek JM, McCray PB, Ganz T, Kearney WR, Tack BF. The NMR structure of human β-defensin-2 reveals a novel α-helical segment Biochemistry. 40: 3810-3816. PMID 11300761 DOI: 10.1021/Bi002519D  0.96
2001 Henneman E, Dracup K, Ganz T, Molayeme O, Cooper C. Effect of a collaborative weaning plan on patient outcome in the critical care setting. Critical Care Medicine. 29: 297-303. PMID 11246309 DOI: 10.1097/00003246-200102000-00013  0.96
2001 Peng Jia H, Schutte BC, Schudy A, Linzmeier R, Guthmiller JM, Johnson GK, Tack BF, Mitros JP, Rosenthal A, Ganz T, McCray PB. Discovery of new human β-defensins using a genomics-based approach Gene. 263: 211-218. PMID 11223260 DOI: 10.1016/S0378-1119(00)00569-2  0.96
2001 Ganz T. Defensins in the urinary tract and other tissues Journal of Infectious Diseases. 183. PMID 11171012 DOI: 10.1086/318838  0.96
2001 Cole AM, Shi J, Ceccarelli A, Kim YH, Park A, Ganz T. Inhibition of neutrophil elastase prevents cathelicidin activation and impairs clearance of bacteria from wounds Blood. 97: 297-304. PMID 11133774 DOI: 10.1182/Blood.V97.1.297  0.96
2001 Park CH, Valore EV, Waring AJ, Ganz T. Hepcidin, a Urinary Antimicrobial Peptide Synthesized in the Liver Journal of Biological Chemistry. 276: 7806-7810. PMID 11113131 DOI: 10.1074/Jbc.M008922200  0.96
2001 Sawai MV, Jia HP, Liu L, Aseyev V, Wiencek JM, PBMJ, Ganz T, Kearney WR, Tack BF. The NMR structure of human beta-defensin-2 reveals a novel alpha-helical segment. Biochemistry. 40: 3810-3816. DOI: 10.2210/Pdb1Fqq/Pdb  0.52
2000 Ganz T. Paneth cells - Guardians of the gut cell hatchery Nature Immunology. 1: 99-100. PMID 11248797 DOI: 10.1038/77884  0.96
2000 Ernst WA, Thoma-Uszynski S, Teitelbaum R, Ko C, Hanson DA, Clayberger C, Krensky AM, Leippe M, Bloom BR, Ganz T, Modlin RL. Granulysin, a T cell product, kills bacteria by altering membrane permeability. Journal of Immunology (Baltimore, Md. : 1950). 165: 7102-8. PMID 11120840 DOI: 10.4049/Jimmunol.165.12.7102  0.96
2000 Bellm L, Lehrer RI, Ganz T. Protegrins: New antibiotics of mammalian origin Expert Opinion On Investigational Drugs. 9: 1731-1742. PMID 11060772 DOI: 10.1517/13543784.9.8.1731  0.96
2000 Cole AM, Ganz T. Human antimicrobial peptides: Analysis and application Biotechniques. 29: 822-831. PMID 11056814 DOI: 10.2144/00294Rv01  0.96
2000 Ortega MR, Ganz T, Milner SM. Human beta defensin is absent in burn blister fluid. Burns : Journal of the International Society For Burn Injuries. 26: 724-6. PMID 11024605 DOI: 10.1016/S0305-4179(00)00052-8  0.96
2000 O'Neil DA, Cole SP, Martin-Porter E, Housley MP, Liu L, Ganz T, Kagnoff MF. Regulation of human beta-defensins by gastric epithelial cells in response to infection with Helicobacter pylori or stimulation with interleukin-1. Infection and Immunity. 68: 5412-5. PMID 10948173 DOI: 10.1128/Iai.68.9.5412-5415.2000  0.96
2000 Cole AM, Wu M, Kim YH, Ganz T. Microanalysis of antimicrobial properties of human fluids Journal of Microbiological Methods. 41: 135-143. PMID 10889310 DOI: 10.1016/S0167-7012(00)00140-8  0.96
2000 Borregaard N, Garred P, Svejgaard A, Elsbach P, Ganz T. Innate immunity: From plants to humans Immunology Today. 21: 68-70. PMID 10652463 DOI: 10.1016/S0167-5699(99)01570-4  0.96
1999 Ganz T. Defensins and host defense Science. 286: 420-421. PMID 10577203 DOI: 10.1126/Science.286.5439.420  0.96
1999 Bevins CI, Martin-Porter E, Ganz T. Defensins and innate host defence of the gastrointestinal tract Gut. 45: 911-915. PMID 10562592 DOI: 10.1136/Gut.45.6.911  0.96
1999 Ganz T. Oxygen-independent microbicidal mechanisms of phagocytes Proceedings of the Association of American Physicians. 111: 390-395. PMID 10519158  0.96
1999 McKay MS, Olson E, Hesla MA, Panyutich A, Ganz T, Perkins S, Rossomando EF. Immunomagnetic recovery of human neutrophil defensins from the human gingival crevice. Oral Microbiology and Immunology. 14: 190-3. PMID 10495714 DOI: 10.1034/J.1399-302X.1999.140308.X  0.96
1999 Bdeir K, Cane W, Canziani G, Chaiken I, Weisel J, Koschinsky ML, Lawn RM, Bannerman PG, Sachais BS, Kuo A, Hancock MA, Tomaszewski J, Raghunath PN, Ganz T, Higazi AAR, et al. Defensin promotes the binding of lipoprotein(a) to vascular matrix Blood. 94: 2007-2019. PMID 10477730  0.96
1999 Ganz T, Lehrer RI. Antibiotic peptides from higher eukaryotes: Biology and applications Molecular Medicine Today. 5: 292-297. PMID 10377520 DOI: 10.1016/S1357-4310(99)01490-2  0.96
1999 Cole AM, Dewan P, Ganz T. Innate antimicrobial activity of nasal secretions Infection and Immunity. 67: 3267-3275. PMID 10377100 DOI: 10.1128/Iai.67.7.3267-3275.1999  0.96
1999 Linzmeier R, Ho CH, Hoang BV, Ganz T. A 450-kb contig of defensin genes on human chromosome 8p23 Gene. 233: 205-211. PMID 10375637 DOI: 10.1016/S0378-1119(99)00136-5  0.96
1999 Shi J, Zhang G, Wu H, Ross C, Blecha F, Ganz T. Porcine epithelial β-defensin 1 is expressed in the dorsal tongue at antimicrobial concentrations Infection and Immunity. 67: 3121-3127. PMID 10338529 DOI: 10.1128/Iai.67.6.3121-3127.1999  0.96
1999 Lehrer RI, Ganz T. Antimicrobial peptides in mammalian and insect host defence Current Opinion in Immunology. 11: 23-27. PMID 10047545 DOI: 10.1016/S0952-7915(99)80005-3  0.96
1999 Rivas L, Ganz T. Eukaryotic antibiotic peptides: Not only a membrane business Drug Discovery Today. 4: 254-256. DOI: 10.1016/S1359-6446(99)01358-6  0.96
1999 Henneman E, Dracup K, Ganz T, Cooper C, Molayeme O. Effect of a collaborative weaning plan on long term ventilator patients in the critical care setting Critical Care Medicine. 27: A95.  0.96
1998 Singh PK, Jia HP, Wiles K, Hesselberth J, Liu L, Conway BA, Greenberg EP, Valore EV, Welsh MJ, Ganz T, Tack BF, McCray PB. Production of beta-defensins by human airway epithelia. Proceedings of the National Academy of Sciences of the United States of America. 95: 14961-6. PMID 9843998 DOI: 10.1073/Pnas.95.25.14961  0.96
1998 Liu L, Wang L, Jia HP, Zhao C, Heng HHQ, Schutte BC, McCray PB, Ganz T. Structure and mapping of the human β-defensin HBD-2 gene and its expression at sites of inflammation Gene. 222: 237-244. PMID 9831658 DOI: 10.1016/S0378-1119(98)00480-6  0.96
1998 Stenger S, Hanson DA, Teitelbaum R, Dewan P, Niazi KR, Froelich CJ, Ganz T, Thoma-Uszynski S, Melián A, Bogdan C, Porcelli SA, Bloom BR, Krensky AM, Modlin RL. An antimicrobial activity of cytolytic T cells mediated by granulysin. Science (New York, N.Y.). 282: 121-5. PMID 9756476 DOI: 10.1126/Science.282.5386.121  0.96
1998 Porter EM, Poles MA, Lee JS, Naitoh J, Bevins CL, Ganz T. Isolation of human intestinal defensins from ileal neobladder urine Febs Letters. 434: 272-276. PMID 9742937 DOI: 10.1016/S0014-5793(98)00994-6  0.96
1998 Shi J, Ganz T. The role of protegrins and other elastase-activated polypeptides in the bactericidal properties of porcine inflammatory fluids Infection and Immunity. 66: 3611-3617. PMID 9673240 DOI: 10.1128/Iai.66.8.3611-3617.1998  0.96
1998 Valore EV, Park CH, Quayle AJ, Wiles KR, McCray PB, Ganz T. Human β-defensin-1: An antimicrobial peptide of urogenital tissues Journal of Clinical Investigation. 101: 1633-1642. PMID 9541493 DOI: 10.1172/Jci1861  0.96
1998 Zhang G, Wu H, Shi J, Ganz T, Ross CR, Blecha F. Molecular cloning and tissue expression of porcine β-defensin-1 Febs Letters. 424: 37-40. PMID 9537511 DOI: 10.1016/S0014-5793(98)00134-3  0.96
1998 Ganz T, Lehrer RI. Antimicrobial peptides of vertebrates Current Opinion in Immunology. 10: 41-44. PMID 9523109 DOI: 10.1016/S0952-7915(98)80029-0  0.96
1998 Ganz T. Defensins are not the principal antimicrobial substances in ASL Pediatric Pulmonology. 26: 130-131.  0.96
1997 Ganz T, Weiss J. Antimicrobial peptides of phagocytes and epithelia Seminars in Hematology. 34: 343-354. PMID 9347585  0.96
1997 Valore EV, Ganz T. Laboratory production of antimicrobial peptides in native conformation Methods in Molecular Biology (Clifton, N.J.). 78: 115-131. PMID 9276301 DOI: 10.1385/0-89603-408-9:115  0.96
1997 Liu L, Zhao C, Heng HHQ, Ganz T. The human β-defensin-1 and α-defensins are encoded by adjacent genes: Two peptide families with differing disulfide topology share a common ancestry Genomics. 43: 316-320. PMID 9268634 DOI: 10.1006/Geno.1997.4801  0.96
1997 Higazi AA, Lavi E, Bdeir K, Ulrich AM, Jamieson DG, Rader DJ, Usher DC, Kane W, Ganz T, Cines DB. Defensin stimulates the binding of lipoprotein (a) to human vascular endothelial and smooth muscle cells. Blood. 89: 4290-8. PMID 9192751 DOI: 10.1182/Blood.V89.12.4290  0.96
1997 Porter EM, Van Dam E, Valore EV, Ganz T. Broad-spectrum antimicrobial activity of human intestinal defensin 5 Infection and Immunity. 65: 2396-2401. PMID 9169780 DOI: 10.1128/Iai.65.6.2396-2401.1997  0.96
1997 Porter EM, Liu L, Oren A, Anton PA, Ganz T. Localization of human intestinal defensin 5 in paneth cell granules Infection and Immunity. 65: 2389-2395. PMID 9169779 DOI: 10.1128/Iai.65.6.2389-2395.1997  0.96
1997 Soong LB, Ganz T, Ellison A, Caughey GH. Purification and characterization of defensins from cystic fibrosis sputum Inflammation Research. 46: 98-102. PMID 9098722 DOI: 10.1007/S000110050114  0.96
1997 Lohner K, Latal A, Lehrer RI, Ganz T. Differential scanning microcalorimetry indicates that human defensin, HNP-2, interacts specifically with biomembrane mimetic systems Biochemistry. 36: 1525-1531. PMID 9063901 DOI: 10.1021/Bi961300P  0.96
1997 Ganz T, Lehrer RI. Antimicrobial peptides of leukocytes Current Opinion in Hematology. 4: 53-58. PMID 9050380 DOI: 10.1097/00062752-199704010-00009  0.96
1997 Panyutich A, Shi J, Boutz PL, Zhao C, Ganz T. Porcine polymorphonuclear leukocytes generate extracellular microbicidal activity by elastase-mediated activation of secreted proprotegrins Infection and Immunity. 65: 978-985. PMID 9038306 DOI: 10.1128/Iai.65.3.978-985.1997  0.96
1996 Lehrer RI, Ganz T. Endogenous vertebrate antibiotics. Defensins, protegrins, and other cysteine-rich antimicrobial peptides Annals of the New York Academy of Sciences. 797: 228-239. PMID 8993365 DOI: 10.1111/J.1749-6632.1996.Tb52963.X  0.96
1996 Higazi AAR, Ganz T, Kariko K, Cines DB. Defensin modulates tissue-type plasminogen activator and plasminogen binding to fibrin and endothelial cells Journal of Biological Chemistry. 271: 17650-17655. PMID 8663495 DOI: 10.1074/Jbc.271.30.17650  0.96
1996 Valore EV, Martin E, Harwig SSL, Ganz T. Intramolecular inhibition of human defensin HNP-1 by its propiece Journal of Clinical Investigation. 97: 1624-1629. PMID 8601627 DOI: 10.1172/Jci118588  0.96
1996 Heng LH, Zhao C, Ganz T. Human alpha- and beta-defensins evolved from a common premammalian ancestor peptide Journal of Investigative Medicine. 44.  0.96
1996 Valoce E, Quayie A, Robbins C, Ganz T. A human beta-defensin is produced by urogenital epithelia Journal of Investigative Medicine. 44.  0.96
1996 Higazi AAIR, Ganz T, Kariko K, Cines D. Defensin modulates IPA and plasminogen binding to fibrin and endothelial cells Fibrinolysis. 10: 33.  0.96
1995 Panyutich AV, Hiemstra PS, van Wetering S, Ganz T. Human neutrophil defensin and serpins form complexes and inactivate each other American Journal of Respiratory Cell and Molecular Biology. 12: 351-357. PMID 7873202 DOI: 10.1165/Ajrcmb.12.3.7873202  0.96
1995 Liu L, Ganz T. The pro region of human neutrophil defensin contains a motif that is essential for normal subcellular sorting Blood. 85: 1095-1103. PMID 7849297 DOI: 10.1182/Blood.V85.4.1095.Bloodjournal8541095  0.96
1995 Liu L, Oren A, Ganz T. Murine 32D cl3 cells - A transfectable model of phagocyte granule formation Journal of Immunological Methods. 181: 253-258. PMID 7745254 DOI: 10.1016/0022-1759(95)00009-Y  0.96
1995 Martin E, Ganz T, Lehrer RI. Defensins and other endogenous peptide antibiotics of vertebrates Journal of Leukocyte Biology. 58: 128-136. PMID 7643008 DOI: 10.1002/Jlb.58.2.128  0.96
1995 Zhao C, Ganz T, Lehrer RI. The structure of porcine protegrin genes Febs Letters. 368: 197-202. PMID 7628604 DOI: 10.1016/0014-5793(95)00633-K  0.96
1995 Zhao C, Ganz T, Lehrer RI. Structures of genes for two cathelin-associated antimicrobial peptides: prophenin-2 and PR-39 Febs Letters. 376: 130-134. PMID 7498526 DOI: 10.1016/0014-5793(95)01237-3  0.96
1994 Couto MA, Liu L, Lehrer RI, Ganz T. Inhibition of intracellular Histoplasma capsulatum replication by murine macrophages that produce human defensin Infection and Immunity. 62: 2375-2378. PMID 8188361 DOI: 10.1128/Iai.62.6.2375-2378.1994  0.96
1994 Harwig SSL, Ganz T, Lehrer RI. Neutrophil defensins: Purification, characterization, and antimicrobial testing Methods in Enzymology. 236: 160-172. PMID 7968608 DOI: 10.1016/0076-6879(94)36015-4  0.96
1994 Ganz T, Lehrer RI. Defensins Current Opinion in Immunology. 6: 584-589. PMID 7946046 DOI: 10.1097/00006454-198605000-00047  0.96
1994 Panyutich AV, Szold O, Poon PH, Tseng Y, Ganz T. Identification of defensin binding to C1 complement Febs Letters. 356: 169-173. PMID 7805831 DOI: 10.1016/0014-5793(94)01261-X  0.96
1994 Ganz T. Biosynthesis of defensins and other antimicrobial peptides Ciba Foundation Symposium. 186: 62-71; discussion 71. PMID 7768158  0.96
1994 Kagan BL, Ganz T, Lehrer RI. Defensins: a family of antimicrobial and cytotoxic peptides. Toxicology. 87: 131-49. PMID 7512758 DOI: 10.1016/0300-483X(94)90158-9  0.96
1993 Linzmeier R, Michaelson D, Liu L, Ganz T. The structure of neutrophil defensin genes Febs Letters. 321: 267-273. PMID 8477861 DOI: 10.1016/0014-5793(93)80122-B  0.96
1993 Lehrer RI, Lichtenstein AK, Ganz T. Defensins: Antimicrobial and cytotoxic peptides of mammalian cells Annual Review of Immunology. 11: 105-128. PMID 8476558 DOI: 10.1146/Annurev.Iy.11.040193.000541  0.96
1993 Nygaard SD, Ganz T, Peterson MW. Defensins reduce the barrier integrity of a cultured epithelial monolayer without cytotoxicity American Journal of Respiratory Cell and Molecular Biology. 8: 193-200. PMID 8427710 DOI: 10.1165/Ajrcmb/8.2.193  0.96
1993 Panyutich AV, Panyutich EA, Krapivin VA, Baturevich EA, Ganz T. Plasma defensin concentrations are elevated in patients with septicemia or bacterial meningitis The Journal of Laboratory and Clinical Medicine. 122: 202-207. PMID 8340706 DOI: 10.5555/Uri:Pii:0022214393900587  0.96
1993 Ganz T, Liu L, Valore EV, Oren A. Posttranslational processing and targeting of transgenic human defensin in murine granulocyte, macrophage, fibroblast, and pituitary adenoma cell lines Blood. 82: 641-650. PMID 8329717 DOI: 10.1182/Blood.V82.2.641.Bloodjournal822641  0.96
1993 Linzmeier R, Michaelson D, Liu L, Ganz T. Errata and corrigendaThe structure of neutrophil defensin genes Febs Letters. 326. PMID 8325384 DOI: 10.1016/0014-5793(93)81813-F  0.52
1993 Ganz T. Macrophage function New Horizons (Baltimore, Md.). 1: 23-27. PMID 7922389  0.96
1993 Panyutich AV, Baturevich EA, Kolesnikova TS, Ganz T. The effect of biotinylation on the antigenic specificity of anti-defensin monoclonal antibodies Journal of Immunological Methods. 158: 237-242. PMID 7679133 DOI: 10.1016/0022-1759(93)90219-W  0.96
1992 Michaelson D, Rayner J, Couto M, Ganz T. Cationic defensins arise from charge-neutralized propeptides: A mechanism for avoiding leukocyte autocytotoxicity? Journal of Leukocyte Biology. 51: 634-639. PMID 1613398 DOI: 10.1002/Jlb.51.6.634  0.96
1992 Sherman MP, Ganz T. Host defense in pulmonary alveoli Annual Review of Physiology. 54: 331-350. PMID 1562178 DOI: 10.1146/Annurev.Ph.54.030192.001555  0.96
1992 Ganz T, Oren A, Lehrer RI. Defensins: microbicidal and cytotoxic peptides of mammalian host defense cells Medical Microbiology and Immunology. 181: 99-105. PMID 1406461 DOI: 10.1007/Bf00189428  0.96
1992 Valore EV, Ganz T. Posttranslational processing of defensins in immature human myeloid cells Blood. 79: 1538-1544. PMID 1339298 DOI: 10.1182/Blood.V79.6.1538.Bloodjournal7961538  0.96
1992 Lehrer RI, Ganz T. Defensins: endogenous antibiotic peptides from human leukocytes Ciba Foundation Symposium. 171: 276-290; discussion . PMID 1302183  0.96
1992 Misuno NI, Kolesnikova TS, Lehrer RI, Ganz T, Voitenok NN. Effect of defensin HNP-1 of human neutrophils on production of tumor necrosis factor α by human blood monocytes in vitro Bulletin of Experimental Biology and Medicine. 113: 709-712. DOI: 10.1007/BF00783767  0.96
1991 Borenstein LA, Ganz T, Sell S, Lehrer RI, Miller JN. Contribution of rabbit leukocyte defensins to the host response in experimental syphilis Infection and Immunity. 59: 1368-1377. PMID 2004817 DOI: 10.1128/Iai.59.4.1368-1377.1991  0.96
1991 Lehrer RI, Ganz T, Selsted ME. Defensins: Endogenous antibiotic peptides of animal cells Cell. 64: 229-230. PMID 1988144 DOI: 10.1016/0092-8674(91)90632-9  0.96
1991 Panyutich AV, Voitenok NN, Lehrer RI, Ganz T. An enzyme immunoassay for human defensins Journal of Immunological Methods. 141: 149-155. PMID 1880422 DOI: 10.1016/0022-1759(91)90141-2  0.96
1991 Panyutich A, Ganz T. Activated alpha 2-macroglobulin is a principal defensin-binding protein American Journal of Respiratory Cell and Molecular Biology. 5: 101-106. PMID 1716445 DOI: 10.1165/Ajrcmb/5.2.101  0.96
1990 Okrent DG, Lichtenstein AK, Ganz T. Direct cytotoxicity of polymorphonuclear leukocyte granule proteins to human lung-derived cells and endothelial cells. The American Review of Respiratory Disease. 141: 179-85. PMID 2297176 DOI: 10.1164/Ajrccm/141.1.179  0.96
1990 Lehrer RI, Ganz T. Antimicrobial polypeptides of human neutrophils Blood. 76: 2169-2181. PMID 2257291 DOI: 10.1182/Blood.V76.11.2169.Bloodjournal76112169  0.96
1990 Miyasaki KT, Bodeau AL, Ganz T, Selsted ME, Lehrer RI. In vitro sensitivity of oral, gram-negative, facultative bacteria to the bactericidal activity of human neutrophil defensins. Infection and Immunity. 58: 3934-40. PMID 2254020 DOI: 10.1128/Iai.58.12.3934-3940.1990  0.96
1990 Eisenhauer P, Harwig SSSL, Szklarek D, Ganz T, Lehrer RI. Polymorphic expression of defensins in neutrophils from outbred rats Infection and Immunity. 58: 3899-3902. PMID 2254017 DOI: 10.1128/Iai.58.12.3899-3902.1990  0.96
1990 Saxon A, Shanahan F, Landers C, Ganz T, Targan S. A distinct subset of antineutrophil cytoplasmic antibodies is associated with inflammatory bowel disease The Journal of Allergy and Clinical Immunology. 86: 202-210. PMID 2200820 DOI: 10.1016/S0091-6749(05)80067-3  0.96
1990 Miyasaki KT, Bodeau AL, Selsted ME, Ganz T, Lehrer RI. Killing of oral, gram-negative, facultative bacteria by the rabbit defensin, NP-1. Oral Microbiology and Immunology. 5: 315-9. PMID 2098709 DOI: 10.1111/J.1399-302X.1990.Tb00432.X  0.96
1990 Kagan BL, Selsted ME, Ganz T, Lehrer RI. Antimicrobial defensin peptides form voltage-dependent ion-permeable channels in planar lipid bilayer membranes. Proceedings of the National Academy of Sciences of the United States of America. 87: 210-4. PMID 1688654 DOI: 10.1073/Pnas.87.1.210  0.96
1989 Chng HH, Ganz T, Saxon A. The utility of detecting of autoantibodies against neutrophil cytoplasmic components in Wegener's granulomatosis Annals of Allergy. 63: 411-416. PMID 2817531  0.96
1989 Lehrer RI, Barton A, Daher KA, Harwig SSL, Ganz T, Selsted ME. Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity Journal of Clinical Investigation. 84: 553-561. PMID 2668334 DOI: 10.1172/Jci114198  0.96
1989 Territo MC, Ganz T, Selsted ME, Lehrer R. Monocyte-chemotactic activity of defensins from human neutrophils Journal of Clinical Investigation. 84: 2017-2020. PMID 2592571 DOI: 10.1172/Jci114394  0.96
1989 Eisenhauer PB, Harwig SSL, Szklarek D, Ganz T, Selsted ME, Lehrer RI. Purification and antimicrobial properties of three defensins from rat neutrophils Infection and Immunity. 57: 2021-2027. PMID 2543629 DOI: 10.1128/Iai.57.7.2021-2027.1989  0.96
1989 Joiner KA, Ganz T, Albert J, Rotrosen D. The opsonizing ligand on Salmonella typhimurium influences incorporation of specific, but not azurophil, granule constituents into neutrophil phagosomes Journal of Cell Biology. 109: 2771-2782. PMID 2480351 DOI: 10.1083/Jcb.109.6.2771  0.96
1988 Lehrer RI, Ganz T, Szklarek D, Selsted ME. Modulation of the in vitro candidacidal activity of human neutrophil defensins by target cell metabolism and divalent cations Journal of Clinical Investigation. 81: 1829-1835. PMID 3290255 DOI: 10.1172/Jci113527  0.96
1988 Lehrer RI, Ganz T, Selsted ME, Babior BM, Curnutte JT. Neutrophils and host defense Annals of Internal Medicine. 109: 127-142. PMID 3289431 DOI: 10.7326/0003-4819-109-2-127  0.96
1988 Lehrer RI, Ganz T, Selsted ME. Oxygen-independent bactericidal systems. Mechanisms and disorders Hematology/Oncology Clinics of North America. 2: 159-169. PMID 3279018 DOI: 10.1016/S0889-8588(18)30635-X  0.96
1988 Daher KA, Lehrer RI, Ganz T, Kronenberg M. Isolation and characterization of human defensin cDNA clones Proceedings of the National Academy of Sciences of the United States of America. 85: 7327-7331. PMID 3174637 DOI: 10.1073/Pnas.85.19.7327  0.96
1988 Lichtenstein AK, Ganz T, Nguyen TM, Selsted ME, Lehrer RI. Mechanism of target cytolysis by peptide defensins. Target cell metabolic activities, possibly involving endocytosis, are crucial for expression of cytotoxicity Journal of Immunology. 140: 2686-2694. PMID 3162745  0.96
1988 Lehrer RI, Barton A, Ganz T. Concurrent assessment of inner and outer membrane permeabilization and bacteriolysis in E. coli by multiple-wavelength spectrophotometry Journal of Immunological Methods. 108: 153-158. PMID 3127470 DOI: 10.1016/0022-1759(88)90414-0  0.96
1988 Ganz T, Metcalf JA, Gallin JI, Boxer LA, Lehrer RI. Microbicidal/cytotoxic proteins of neutrophils are deficient in two disorders: Chediak-Higashi syndrome and 'specific' granule deficiency Journal of Clinical Investigation. 82: 552-556. PMID 2841356 DOI: 10.1172/Jci113631  0.96
1988 Lichtenstein AK, Ganz T, Selsted ME, Lehrer RI. Synergistic cytolysis mediated by hydrogen peroxide combined with peptide defensins Cellular Immunology. 114: 104-116. PMID 2836069 DOI: 10.1016/0008-8749(88)90258-4  0.96
1987 Ganz T. Extracellular release of antimicrobial defensins by human polymorphonuclear leukocytes Infection and Immunity. 55: 568-571. PMID 3643886 DOI: 10.1128/Iai.55.3.568-571.1987  0.96
1987 Greenwald GI, Ganz T. Defensins mediate the microbial activity of human neutrophil granule extract against Acinetobacter calcoaceticus Infection and Immunity. 55: 1365-1368. PMID 3570467 DOI: 10.1128/Iai.55.6.1365-1368.1987  0.96
1987 Ganz T. Preventive therapy of emphysema: lessons from the elastase model American Review of Respiratory Disease. 135: 984. PMID 3565949 DOI: 10.1164/Arrd.1987.135.4.984A  0.96
1986 Lichtenstein A, Ganz T, Selsted ME, Lehrer RI. In vitro tumor cell cytolysis mediated by peptide defensins of human and rabbit granulocytes Blood. 68: 1407-1410. PMID 3779104 DOI: 10.1182/Blood.V68.6.1407.Bloodjournal6861407  0.96
1986 Lehrer RI, Szklarek D, Ganz T, Selsted ME. Synergistic activity of rabbit granulocyte peptides against Candida albicans Infection and Immunity. 52: 902-904. PMID 3519465 DOI: 10.1128/Iai.52.3.902-904.1986  0.96
1986 Ganz T, Selsted ME, Lehrer RI. Antimicrobial activity of phagocyte granule proteins Seminars in Respiratory Infections. 1: 107-117. PMID 3317602  0.96
1985 Selsted ME, Harwig SSL, Ganz T, Schilling JW, Lehrer RI. Primary structures of three human neutrophil defensins Journal of Clinical Investigation. 76: 1436-1439. PMID 4056036 DOI: 10.1172/Jci112121  0.96
1985 Ganz T, Sherman MP, Selsted ME, Lehrer RI. Newborn rabbit alveolar macrophages are deficient in two microbicidal cationic peptides, MCP-1 and MCP-2 American Review of Respiratory Disease. 132: 901-904. PMID 4051325 DOI: 10.1164/Arrd.1985.132.4.901  0.96
1985 Lehrer RI, Szklarek D, Ganz T, Selsted ME. Correlation of binding of rabbit granulocyte peptides to Candida albicans with candidacidal activity Infection and Immunity. 49: 207-211. PMID 3891625 DOI: 10.1128/Iai.49.1.207-211.1985  0.96
1985 Selsted ME, Szklarek D, Ganz T, Lehrer RI. Activity of rabbit leukocyte peptides against Candida albicans Infection and Immunity. 49: 202-206. PMID 3891624 DOI: 10.1128/Iai.49.1.202-206.1985  0.96
1985 Ganz T, Selsted ME, Szklarek D, Harwig SS, Daher K, Bainton DF, Lehrer RI. Defensins. Natural peptide antibiotics of human neutrophils Journal of Clinical Investigation. 76: 1427-1435. PMID 2997278 DOI: 10.1172/Jci112120  0.96
1985 Lehrer RI, Daher K, Ganz T, Selsted ME. Direct inactivation of viruses by MCP-1 and MCP-2, natural peptide antibiotics from rabbit leukocytes Journal of Virology. 54: 467-472. PMID 2985808 DOI: 10.1128/Jvi.54.2.467-472.1985  0.96
1985 Selsted ME, Ganz T, Schilling JW, Lehrer RI. Biochemical characterization of 'defensins': Novel antibiotic peptides from human leukocytes Federation Proceedings. 44.  0.96
1985 Ganz T, Selsted ME, Szklarek D, Lehrer RI. Antimicrobial properties of human defensins: Major peptides of human neutrophils Federation Proceedings. 44.  0.96
1983 Andersen RD, Birren BW, Ganz T, Piletz JE, Herschman HR. Molecular cloning of the rat metallothionein 1 (MT-1) mRNA sequence. Dna (Mary Ann Liebert, Inc.). 2: 15-22. PMID 6687866  0.96
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