Celia W. Goulding - Publications

Biological Sciences - Ph.D. University of California, Irvine, Irvine, CA 

67 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Burley KH, Cuthbert BJ, Basu P, Newcombe J, Irimpan EM, Quechol R, Foik IP, Mobley DL, Beste DJV, Goulding CW. Structural and Molecular Dynamics of Malic Enzyme, a Potential Anti-TB Drug Target. Acs Infectious Diseases. PMID 33356117 DOI: 10.1021/acsinfecdis.0c00735  1
2020 Nainar S, Cuthbert BJ, Lim NM, England WE, Ke K, Sophal K, Quechol R, Mobley DL, Goulding CW, Spitale RC. An optimized chemical-genetic method for cell-specific metabolic labeling of RNA. Nature Methods. PMID 32015544 DOI: 10.1038/S41592-019-0726-Y  1
2020 Chao A, Goulding CW. Correction to "A Single Mutation in the Heme-Degrading Protein, MhuD, Results in Different Products". Biochemistry. PMID 31999434 DOI: 10.1021/Acs.Biochem.0C00037  1
2019 Chao A, Burley K, Sieminski PJ, de Miranda R, Chen X, Mobley DL, Goulding C. The structure of a Mycobacterium tuberculosis heme-degrading protein, MhuD, variant in complex with its product. Biochemistry. PMID 31638374 DOI: 10.1021/Acs.Biochem.9B00726  1
2019 Chao A, Goulding C. A single mutation in the Mycobacterium tuberculosis heme-degrading protein, MhuD, results in different products. Biochemistry. PMID 30605595 DOI: 10.1021/Acs.Biochem.8B01198  1
2018 Chao A, Sieminski PJ, Owens CP, Goulding CW. Iron Acquisition in Mycobacterium tuberculosis. Chemical Reviews. PMID 30474981 DOI: 10.1021/Acs.Chemrev.8B00285  1
2018 Thakuri B, Graves AB, Chao A, Johansen SL, Goulding CW, Liptak MD. The affinity of MhuD for heme is consistent with a heme degrading function in vivo. Metallomics : Integrated Biometal Science. PMID 30239544 DOI: 10.1039/C8Mt00238J  1
2017 Burley K, Goulding CW. Protein engineering: Redirecting membrane machinery. Nature Chemical Biology. 13: 927-928. PMID 28820876 DOI: 10.1038/Nchembio.2451  1
2016 Costa DL, Namasivayam S, Amaral EP, Arora K, Chao A, Mittereder LR, Maiga M, Boshoff HI, Barry CE, Goulding CW, Andrade BB, Sher A. Pharmacological Inhibition of Host Heme Oxygenase-1 Suppresses Mycobacterium tuberculosis Infection In Vivo by a Mechanism Dependent on T Lymphocytes. Mbio. 7. PMID 27795400 DOI: 10.1128/Mbio.01675-16  1
2016 Johnson PM, Beck CM, Morse RP, Garza-Sánchez F, Low DA, Hayes CS, Goulding CW. Unraveling the essential role of CysK in CDI toxin activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27531961 DOI: 10.1073/Pnas.1607112113  0.92
2016 Johnson PM, Gucinski GC, Garza-Sánchez F, Wong T, Hung LW, Hayes CS, Goulding CW. Functional Diversity of Cytotoxic tRNase/immunity Protein Complexes from Burkholderia pseudomallei. The Journal of Biological Chemistry. PMID 27445337 DOI: 10.1074/Jbc.M116.736074  0.92
2016 Diaz-Ochoa VE, Lam D, Lee CS, Klaus S, Behnsen J, Liu JZ, Chim N, Nuccio SP, Rathi SG, Mastroianni JR, Edwards RA, Jacobo CM, Cerasi M, Battistoni A, Ouellette AJ, ... Goulding CW, et al. Salmonella Mitigates Oxidative Stress and Thrives in the Inflamed Gut by Evading Calprotectin-Mediated Manganese Sequestration. Cell Host & Microbe. 19: 814-825. PMID 27281571 DOI: 10.1016/J.Chom.2016.05.005  0.92
2016 Matsui T, Nambu S, Goulding CW, Takahashi S, Fujii H, Ikeda-Saito M. Unique coupling of mono- and dioxygenase chemistries in a single active site promotes heme degradation. Proceedings of the National Academy of Sciences of the United States of America. PMID 27006503 DOI: 10.1073/Pnas.1523333113  0.92
2015 Morse RP, Willett JL, Johnson PM, Zheng M, Credali A, Iniguez A, Nowick JS, Hayes CS, Goulding CW. Diversification of β-augmentation interactions between CDI toxin/immunity proteins. Journal of Molecular Biology. PMID 26449640 DOI: 10.1016/J.Jmb.2015.09.020  0.92
2015 Willett JL, Ruhe ZC, Goulding CW, Low DA, Hayes CS. Contact-dependent growth inhibition (CDI) and CdiB/CdiA two-partner secretion proteins. Journal of Molecular Biology. PMID 26388411 DOI: 10.1016/J.Jmb.2015.09.010  0.92
2015 Chim N, Torres R, Liu Y, Capri J, Batot G, Whitelegge JP, Goulding CW. The Structure and Interactions of Periplasmic Domains of Crucial MmpL Membrane Proteins from Mycobacterium tuberculosis. Chemistry & Biology. 22: 1098-107. PMID 26278184 DOI: 10.1016/J.Chembiol.2015.07.013  0.92
2015 Behera RK, Torres R, Tosha T, Bradley JM, Goulding CW, Theil EC. Fe(2+) substrate transport through ferritin protein cage ion channels influences enzyme activity and biomineralization. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. PMID 26202907 DOI: 10.1007/S00775-015-1279-X  0.92
2015 Tan K, Johnson PM, Stols L, Boubion B, Eschenfeldt W, Babnigg G, Hayes CS, Joachimiak A, Goulding CW. The structure of a contact-dependent growth-inhibition (CDI) immunity protein from Neisseria meningitidis MC58. Acta Crystallographica. Section F, Structural Biology Communications. 71: 702-9. PMID 26057799 DOI: 10.1107/S2053230X15006585  0.92
2014 Graves AB, Morse RP, Chao A, Iniguez A, Goulding CW, Liptak MD. Crystallographic and spectroscopic insights into heme degradation by Mycobacterium tuberculosis MhuD. Inorganic Chemistry. 53: 5931-40. PMID 24901029 DOI: 10.1021/Ic500033B  0.92
2014 Contreras H, Joens MS, McMath LM, Le VP, Tullius MV, Kimmey JM, Bionghi N, Horwitz MA, Fitzpatrick JA, Goulding CW. Characterization of a Mycobacterium tuberculosis nanocompartment and its potential cargo proteins. The Journal of Biological Chemistry. 289: 18279-89. PMID 24855650 DOI: 10.1074/Jbc.M114.570119  0.92
2014 Contreras H, Chim N, Credali A, Goulding CW. Heme uptake in bacterial pathogens. Current Opinion in Chemical Biology. 19: 34-41. PMID 24780277 DOI: 10.1016/J.Cbpa.2013.12.014  0.92
2014 Torres R, Lan B, Latif Y, Chim N, Goulding CW. Structural snapshots along the reaction pathway of Yersinia pestis RipA, a putative butyryl-CoA transferase. Acta Crystallographica. Section D, Biological Crystallography. 70: 1074-85. PMID 24699651 DOI: 10.1107/S1399004714000911  0.92
2014 Beck CM, Morse RP, Cunningham DA, Iniguez A, Low DA, Goulding CW, Hayes CS. CdiA from Enterobacter cloacae delivers a toxic ribosomal RNase into target bacteria. Structure (London, England : 1993). 22: 707-18. PMID 24657090 DOI: 10.1016/J.Str.2014.02.012  0.92
2014 Chim N, Johnson PM, Goulding CW. Insights into redox sensing metalloproteins in Mycobacterium tuberculosis. Journal of Inorganic Biochemistry. 133: 118-26. PMID 24314844 DOI: 10.1016/J.Jinorgbio.2013.11.003  0.92
2013 Chim N, Harmston CA, Guzman DJ, Goulding CW. Structural and biochemical characterization of the essential DsbA-like disulfide bond forming protein from Mycobacterium tuberculosis. Bmc Structural Biology. 13: 23. PMID 24134223 DOI: 10.1186/1472-6807-13-23  0.92
2013 Pham JD, Chim N, Goulding CW, Nowick JS. Structures of oligomers of a peptide from β-amyloid. Journal of the American Chemical Society. 135: 12460-7. PMID 23927812 DOI: 10.1021/Ja4068854  0.92
2013 Owens CP, Chim N, Goulding CW. Insights on how the Mycobacterium tuberculosis heme uptake pathway can be used as a drug target. Future Medicinal Chemistry. 5: 1391-403. PMID 23919550 DOI: 10.4155/Fmc.13.109  0.92
2013 Owens CP, Chim N, Graves AB, Harmston CA, Iniguez A, Contreras H, Liptak MD, Goulding CW. The Mycobacterium tuberculosis secreted protein Rv0203 transfers heme to membrane proteins MmpL3 and MmpL11. The Journal of Biological Chemistry. 288: 21714-28. PMID 23760277 DOI: 10.1074/Jbc.M113.453076  0.92
2013 Matsui T, Nambu S, Ono Y, Goulding CW, Tsumoto K, Ikeda-Saito M. Heme degradation by Staphylococcus aureus IsdG and IsdI liberates formaldehyde rather than carbon monoxide. Biochemistry. 52: 3025-7. PMID 23600533 DOI: 10.1021/Bi400382P  0.92
2013 Nambu S, Matsui T, Goulding CW, Takahashi S, Ikeda-Saito M. A new way to degrade heme: the Mycobacterium tuberculosis enzyme MhuD catalyzes heme degradation without generating CO. The Journal of Biological Chemistry. 288: 10101-9. PMID 23420845 DOI: 10.1074/Jbc.M112.448399  0.92
2013 Honsa ES, Owens CP, Goulding CW, Maresso AW. The near-iron transporter (NEAT) domains of the anthrax hemophore IsdX2 require a critical glutamine to extract heme from methemoglobin. The Journal of Biological Chemistry. 288: 8479-90. PMID 23364793 DOI: 10.1074/Jbc.M112.430009  0.92
2013 McMath LM, Contreras H, Owens CP, Goulding CW. The structural characterization of bacterioferritin, BfrA, from Mycobacterium tuberculosis Journal of Porphyrins and Phthalocyanines. 17: 229-239. DOI: 10.1142/S1088424613500211  0.92
2012 Morse RP, Nikolakakis KC, Willett JL, Gerrick E, Low DA, Hayes CS, Goulding CW. Structural basis of toxicity and immunity in contact-dependent growth inhibition (CDI) systems. Proceedings of the National Academy of Sciences of the United States of America. 109: 21480-5. PMID 23236156 DOI: 10.1073/Pnas.1216238110  0.92
2012 Chim N, Owens CP, Contreras H, Goulding CW. Advances In Mycobacterium Tuberculosis Therapeutics Discovery Utlizing Structural Biology. Infectious Disorders Drug Targets. PMID 23167715  0.8
2012 Ekworomadu MT, Poor CB, Owens CP, Balderas MA, Fabian M, Olson JS, Murphy F, Bakkalbasi E, Balkabasi E, Honsa ES, He C, Goulding CW, Maresso AW. Differential function of lip residues in the mechanism and biology of an anthrax hemophore. Plos Pathogens. 8: e1002559. PMID 22412371 DOI: 10.1371/Journal.Ppat.1002559  0.92
2012 Owens CP, Du J, Dawson JH, Goulding CW. Characterization of heme ligation properties of Rv0203, a secreted heme binding protein involved in Mycobacterium tuberculosis heme uptake. Biochemistry. 51: 1518-31. PMID 22283334 DOI: 10.1021/Bi2018305  0.92
2012 Torres R, Chim N, Sankaran B, Pujol C, Bliska JB, Goulding CW. Structural insights into RipC, a putative citrate lyase β subunit from a Yersinia pestis virulence operon. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 68: 2-7. PMID 22232161 DOI: 10.1107/S1744309111048056  0.92
2011 Khan IH, Ravindran R, Krishnan VV, Awan IN, Rizvi SK, Saqib MA, Shahzad MI, Tahseen S, Ireton G, Goulding CW, Felgner P, DeRiemer K, Khanum A, Luciw PA. Plasma antibody profiles as diagnostic biomarkers for tuberculosis. Clinical and Vaccine Immunology : Cvi. 18: 2148-53. PMID 21976221 DOI: 10.1128/Cvi.05304-11  0.92
2011 Torres R, Swift RV, Chim N, Wheatley N, Lan B, Atwood BR, Pujol C, Sankaran B, Bliska JB, Amaro RE, Goulding CW. Biochemical, structural and molecular dynamics analyses of the potential virulence factor RipA from Yersinia pestis. Plos One. 6: e25084. PMID 21966419 DOI: 10.1371/Journal.Pone.0025084  0.92
2011 Tullius MV, Harmston CA, Owens CP, Chim N, Morse RP, McMath LM, Iniguez A, Kimmey JM, Sawaya MR, Whitelegge JP, Horwitz MA, Goulding CW. Discovery and characterization of a unique mycobacterial heme acquisition system. Proceedings of the National Academy of Sciences of the United States of America. 108: 5051-6. PMID 21383189 DOI: 10.1073/Pnas.1009516108  0.92
2011 Chim N, Habel JE, Johnston JM, Krieger I, Miallau L, Sankaranarayanan R, Morse RP, Bruning J, Swanson S, Kim H, Kim CY, Li H, Bulloch EM, Payne RJ, Manos-Turvey A, ... ... Goulding CW, et al. The TB Structural Genomics Consortium: a decade of progress. Tuberculosis (Edinburgh, Scotland). 91: 155-72. PMID 21247804 DOI: 10.1016/J.Tube.2010.11.009  0.92
2010 McMath LM, Habel JE, Sankaran B, Yu M, Hung LW, Goulding CW. Crystallization and preliminary X-ray crystallographic analysis of a Mycobacterium tuberculosis ferritin homolog, BfrB. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1657-61. PMID 21139218 DOI: 10.1107/S1744309110042958  0.92
2010 Chim N, Riley R, The J, Im S, Segelke B, Lekin T, Yu M, Hung LW, Terwilliger T, Whitelegge JP, Goulding CW. An extracellular disulfide bond forming protein (DsbF) from Mycobacterium tuberculosis: structural, biochemical, and gene expression analysis. Journal of Molecular Biology. 396: 1211-26. PMID 20060836 DOI: 10.1016/J.Jmb.2009.12.060  0.92
2010 Chim N, Iniguez A, Nguyen TQ, Goulding CW. Unusual diheme conformation of the heme-degrading protein from Mycobacterium tuberculosis. Journal of Molecular Biology. 395: 595-608. PMID 19917297 DOI: 10.1016/J.Jmb.2009.11.025  0.92
2009 Chim N, McMath LM, Beeby M, Goulding CW. Advances in Mycobacterium tuberculosis structural genomics: investigating potential chinks in the armor of a deadly pathogen. Infectious Disorders Drug Targets. 9: 475-92. PMID 19594421 DOI: 10.2174/187152609789105731  0.92
2008 Fox BG, Goulding C, Malkowski MG, Stewart L, Deacon A. Structural genomics: from genes to structures with valuable materials and many questions in between. Nature Methods. 5: 129-32. PMID 18235432 DOI: 10.1038/Nmeth0208-129  0.92
2008 Khan IH, Ravindran R, Yee J, Ziman M, Lewinsohn DM, Gennaro ML, Flynn JL, Goulding CW, DeRiemer K, Lerche NW, Luciw PA. Profiling antibodies to Mycobacterium tuberculosis by multiplex microbead suspension arrays for serodiagnosis of tuberculosis. Clinical and Vaccine Immunology : Cvi. 15: 433-8. PMID 18077619 DOI: 10.1128/Cvi.00354-07  0.92
2007 Murillo AC, Li HY, Alber T, Baker EN, Berger JM, Cherney LT, Cherney MM, Cho YS, Eisenberg D, Garen CR, Goulding CW, Hung LW, Ioerger TR, Jacobs WR, James MN, et al. High throughput crystallography of TB drug targets. Infectious Disorders Drug Targets. 7: 127-39. PMID 17970224 DOI: 10.2174/187152607781001853  0.72
2007 White EL, Southworth K, Ross L, Cooley S, Gill RB, Sosa MI, Manouvakhova A, Rasmussen L, Goulding C, Eisenberg D, Fletcher TM. A novel inhibitor of Mycobacterium tuberculosis pantothenate synthetase. Journal of Biomolecular Screening. 12: 100-5. PMID 17175524 DOI: 10.1177/1087057106296484  0.92
2007 Goulding CW, Bowers PM, Segelke B, Lekin T, Kim CY, Terwilliger TC, Eisenberg D. The structure and computational analysis of Mycobacterium tuberculosis protein CitE suggest a novel enzymatic function. Journal of Molecular Biology. 365: 275-83. PMID 17064730 DOI: 10.1016/J.Jmb.2006.09.086  0.92
2006 Strong M, Goulding CW. Structural proteomics and computational analysis of a deadly pathogen: combating Mycobacterium tuberculosis from multiple fronts. Methods of Biochemical Analysis. 49: 245-69. PMID 16929683 DOI: 10.1002/0471973165.Ch15  0.92
2005 Goulding CW, Apostol MI, Sawaya MR, Phillips M, Parseghian A, Eisenberg D. Regulation by oligomerization in a mycobacterial folate biosynthetic enzyme. Journal of Molecular Biology. 349: 61-72. PMID 15876368 DOI: 10.1016/J.Jmb.2005.03.023  0.92
2004 Goulding CW, Apostol MI, Gleiter S, Parseghian A, Bardwell J, Gennaro M, Eisenberg D. Gram-positive DsbE proteins function differently from Gram-negative DsbE homologs. A structure to function analysis of DsbE from Mycobacterium tuberculosis. The Journal of Biological Chemistry. 279: 3516-24. PMID 14597624 DOI: 10.1074/Jbc.M311833200  0.92
2003 Hsu T, Hingley-Wilson SM, Chen B, Chen M, Dai AZ, Morin PM, Marks CB, Padiyar J, Goulding C, Gingery M, Eisenberg D, Russell RG, Derrick SC, Collins FM, Morris SL, et al. The primary mechanism of attenuation of bacillus Calmette-Guerin is a loss of secreted lytic function required for invasion of lung interstitial tissue. Proceedings of the National Academy of Sciences of the United States of America. 100: 12420-5. PMID 14557547 DOI: 10.1073/Pnas.1635213100  0.92
2003 Goulding CW, Perry LJ, Anderson D, Sawaya MR, Cascio D, Apostol MI, Chan S, Parseghian A, Wang SS, Wu Y, Cassano V, Gill HS, Eisenberg D. Structural genomics of Mycobacterium tuberculosis: a preliminary report of progress at UCLA. Biophysical Chemistry. 105: 361-70. PMID 14499904 DOI: 10.1016/S0301-4622(03)00101-7  0.92
2003 Terwilliger TC, Park MS, Waldo GS, Berendzen J, Hung LW, Kim CY, Smith CV, Sacchettini JC, Bellinzoni M, Bossi R, De Rossi E, Mattevi A, Milano A, Riccardi G, Rizzi M, ... ... Goulding CW, et al. The TB structural genomics consortium: a resource for Mycobacterium tuberculosis biology. Tuberculosis (Edinburgh, Scotland). 83: 223-49. PMID 12906835 DOI: 10.1016/S1472-9792(03)00051-9  0.92
2003 Goulding CW, Perry LJ. Protein production in Escherichia coli for structural studies by X-ray crystallography. Journal of Structural Biology. 142: 133-43. PMID 12718925 DOI: 10.1016/S1047-8477(03)00044-3  0.92
2002 Goulding CW, Apostol M, Anderson DH, Gill HS, Smith CV, Kuo MR, Yang JK, Waldo GS, Suh SW, Chauhan R, Kale A, Bachhawat N, Mande SC, Johnston JM, Lott JS, et al. The TB structural genomics consortium: providing a structural foundation for drug discovery. Current Drug Targets. Infectious Disorders. 2: 121-41. PMID 12462144 DOI: 10.2174/1568005023342551  0.92
2002 Goulding CW, Parseghian A, Sawaya MR, Cascio D, Apostol MI, Gennaro ML, Eisenberg D. Crystal structure of a major secreted protein of Mycobacterium tuberculosis-MPT63 at 1.5-A resolution. Protein Science : a Publication of the Protein Society. 11: 2887-93. PMID 12441386 DOI: 10.1110/Ps.0219002  0.92
2002 Goulding CW, Sawaya MR, Parseghian A, Lim V, Eisenberg D, Missiakas D. Thiol-disulfide exchange in an immunoglobulin-like fold: Structure of the N-terminal domain of DsbD Biochemistry. 41: 6920-6927. PMID 12033924 DOI: 10.1021/Bi016038L  0.92
1998 Matthews RG, Sheppard C, Goulding C. Methylenetetrahydrofolate reductase and methionine synthase: biochemistry and molecular biology. European Journal of Pediatrics. 157: S54-9. PMID 9587027 DOI: 10.1007/Pl00014305  1
1998 Peariso K, Goulding CW, Huang S, Matthews RG, Penner-Hahn JE. Characterization of the zinc binding site in methionine synthase enzymes of Escherichia coli: The role of zinc in the methylation of homocysteine Journal of the American Chemical Society. 120: 8410-8416. DOI: 10.1021/Ja980581G  0.92
1997 Matthews RG, Goulding CW. Enzyme-catalyzed methyl transfers to thiols: the role of zinc. Current Opinion in Chemical Biology. 1: 332-9. PMID 9667865 DOI: 10.1016/S1367-5931(97)80070-1  0.92
1997 Goulding CW, Matthews RG. Cobalamin-dependent methionine synthase from Escherichia coli: involvement of zinc in homocysteine activation. Biochemistry. 36: 15749-57. PMID 9398304 DOI: 10.1021/Bi971988L  0.92
1997 Jarrett JT, Goulding CW, Fluhr K, Huang S, Matthews RG. Purification and assay of cobalamin-dependent methionine synthase from Escherichia coli. Methods in Enzymology. 281: 196-213. PMID 9250984 DOI: 10.1016/S0076-6879(97)81026-9  0.92
1997 Goulding CW, Postigo D, Matthews RG. Cobalamin-dependent methionine synthase is a modular protein with distinct regions for binding homocysteine, methyltetrahydrofolate, cobalamin, and adenosylmethionine. Biochemistry. 36: 8082-91. PMID 9201956 DOI: 10.1021/Bi9705164  0.92
1997 González JC, Goulding CW, Jarrett JT, Peariso K, Penner-Hahn JE, Matthews RG. Methionine synthase: Two unrelated enzymes with the same function Protein Engineering. 10: 57.  0.92
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