| Year |
Citation |
Score |
| 2024 |
Foote JB, Mattox TE, Keeton AB, Chen X, Smith FT, Berry KL, Holmes T, Wang J, Huang CH, Ward AB, Hardy C, Fleten KG, Flatmark K, Yoon KJ, Sarvesh S, ... ... Piazza GA, et al. A Novel Pan-RAS Inhibitor with a Unique Mechanism of Action Blocks Tumor Growth in Mouse Models of GI Cancer. Biorxiv : the Preprint Server For Biology. PMID 38328254 DOI: 10.1101/2023.05.17.541233 |
0.301 |
|
| 2023 |
Tinsley HN, Mathew B, Chen X, Maxuitenko YY, Li N, Lowe WM, Whitt JD, Zhang W, Gary BD, Keeton AB, Grizzle WE, Grubbs CJ, Reynolds RC, Piazza GA. Novel Non-Cyclooxygenase Inhibitory Derivative of Sulindac Inhibits Breast Cancer Cell Growth In Vitro and Reduces Mammary Tumorigenesis in Rats. Cancers. 15. PMID 36765604 DOI: 10.3390/cancers15030646 |
0.795 |
|
| 2022 |
Borneman RM, Gavin E, Musiyenko A, Richter W, Lee KJ, Crossman DK, Andrews JF, Wilhite AM, McClellan S, Aragon I, Ward AB, Chen X, Keeton AB, Berry K, Piazza GA, et al. Phosphodiesterase 10A (PDE10A) as a novel target to suppress β-catenin and RAS signaling in epithelial ovarian cancer. Journal of Ovarian Research. 15: 120. PMID 36324187 DOI: 10.1186/s13048-022-01050-9 |
0.476 |
|
| 2021 |
Mitra Ghosh T, White J, Davis J, Mazumder S, Kansom T, Skarupa E, Barnett GS, Piazza GA, Bird RC, Mitra AK, Yates C, Cummings BS, Arnold RD. Identification and Characterization of Key Differentially Expressed Genes Associated With Metronomic Dosing of Topotecan in Human Prostate Cancer. Frontiers in Pharmacology. 12: 736951. PMID 34938177 DOI: 10.3389/fphar.2021.736951 |
0.303 |
|
| 2021 |
Lee KJ, Chang WL, Chen X, Valiyaveettil J, Ramirez-Alcantara V, Gavin E, Musiyenko A, Madeira da Silva L, Annamdevula NS, Leavesley SJ, Ward A, Mattox TE, Lindsey AS, Andrews J, Zhu B, ... ... Piazza GA, et al. Suppression of colon tumorigenesis in mutant Apc mice by a novel PDE10 inhibitor that reduces oncogenic β-catenin. Cancer Prevention Research (Philadelphia, Pa.). PMID 34584001 DOI: 10.1158/1940-6207.CAPR-21-0208 |
0.474 |
|
| 2021 |
Hafez DE, Hafez E, Eddiasty I, Shih SP, Chien LC, Hong YJ, Lin HY, Keeton AB, Piazza GA, Abdel-Halim M, Abadi AH. Novel thiazolidine derivatives as potent selective pro-apoptotic agents. Bioorganic Chemistry. 114: 105143. PMID 34328854 DOI: 10.1016/j.bioorg.2021.105143 |
0.405 |
|
| 2021 |
Abdel-Halim M, Sigler S, Racheed NAS, Hefnawy A, Fathalla RK, Hammam MA, Maher A, Maxuitenko Y, Keeton AB, Hartmann RW, Engel M, Piazza GA, Abadi AH. From Celecoxib to a Novel Class of Phosphodiesterase 5 Inhibitors: Trisubstituted Pyrazolines as Novel Phosphodiesterase 5 Inhibitors with Extremely High Potency and Phosphodiesterase Isozyme Selectivity. Journal of Medicinal Chemistry. 64: 4462-4477. PMID 33793216 DOI: 10.1021/acs.jmedchem.0c01120 |
0.396 |
|
| 2020 |
Abdel-Halim M, Tinsley H, Keeton AB, Weam M, Atta NH, Hammam MA, Hefnawy A, Hartmann RW, Engel M, Piazza GA, Abadi AH. Discovery of trisubstituted pyrazolines as a novel scaffold for the development of selective phosphodiesterase 5 inhibitors. Bioorganic Chemistry. 104: 104322. PMID 33142429 DOI: 10.1016/j.bioorg.2020.104322 |
0.74 |
|
| 2020 |
Ward AB, Keeton AB, Chen X, Mattox TE, Coley AB, Maxuitenko YY, Buchsbaum DJ, Randall TD, Zhou G, Piazza GA. Enhancing anticancer activity of checkpoint immunotherapy by targeting RAS. Medcomm. 1: 121-128. PMID 33073260 DOI: 10.1002/Mco2.10 |
0.426 |
|
| 2020 |
Emmanouilidi A, Casari I, Gokcen Akkaya B, Maffucci T, Furic L, Guffanti F, Broggini M, Chen X, Maxuitenko YY, Keeton AB, Piazza GA, Linton KJ, Falasca M. Inhibition of the Lysophosphatidylinositol Transporter ABCC1 Reduces Prostate Cancer Cell Growth and Sensitizes to Chemotherapy. Cancers. 12. PMID 32718079 DOI: 10.3390/Cancers12082022 |
0.385 |
|
| 2020 |
Piazza GA, Ward A, Chen X, Maxuitenko Y, Coley A, Aboelella NS, Buchsbaum DJ, Boyd MR, Keeton AB, Zhou G. PDE5 and PDE10 inhibition activates cGMP/PKG signaling to block Wnt/β-catenin transcription, cancer cell growth, and tumor immunity. Drug Discovery Today. PMID 32562844 DOI: 10.1016/J.Drudis.2020.06.008 |
0.605 |
|
| 2020 |
ElHady AK, Shih SP, Chen YC, Liu YC, Ahmed NS, Keeton AB, Piazza GA, Engel M, Abadi AH, Abdel-Halim M. Extending the use of tadalafil scaffold: Development of novel selective phosphodiesterase 5 inhibitors and histone deacetylase inhibitors. Bioorganic Chemistry. 98: 103742. PMID 32199305 DOI: 10.1016/J.Bioorg.2020.103742 |
0.51 |
|
| 2020 |
Al-Wabli RI, Almomen AA, Almutairi MS, Keeton AB, Piazza GA, Attia MI. New Isatin-Indole Conjugates: Synthesis, Characterization, and a Plausible Mechanism of Their in vitro Antiproliferative Activity. Drug Design, Development and Therapy. 14: 483-495. PMID 32099332 DOI: 10.2147/Dddt.S227862 |
0.437 |
|
| 2020 |
Mansour M, El-Saadi MT, Amin NH, Canzoneri J, Keeton A, Piazza G, Abdelrahman H. Quinazolinone-Schiff's Base hybrids as Phosphodiesterase 4B inhibitors with dual activity against COPD and Lung Cancer The Egyptian Journal of Chemistry. 0-0. DOI: 10.21608/Ejchem.2020.28992.2624 |
0.47 |
|
| 2020 |
Piazza GA, Chen X, Ward A, Coley A, Zhou G, Buchsbaum DJ, Maxuitenko Y, Keeton AB. Targeting cGMP/PKG signaling for the treatment or prevention of colorectal cancer with novel sulindac derivatives lacking cyclooxygenase inhibitory activity Oncology Signaling. 3: 1-6. DOI: 10.1016/J.Onsig.2020.04.001 |
0.569 |
|
| 2019 |
Mattox TE, Chen X, Maxuitenko YY, Keeton AB, Piazza GA. Exploiting RAS Nucleotide Cycling as a Strategy for Drugging RAS-Driven Cancers. International Journal of Molecular Sciences. 21. PMID 31878223 DOI: 10.3390/Ijms21010141 |
0.341 |
|
| 2019 |
Almutairi MS, Hassan ES, Keeton AB, Piazza GA, Abdelhameed AS, Attia MI. Antiproliferative activity and possible mechanism of action of certain 5-methoxyindole tethered C-5 functionalized isatins. Drug Design, Development and Therapy. 13: 3069-3078. PMID 31695325 DOI: 10.2147/Dddt.S208241 |
0.397 |
|
| 2019 |
Adamska A, Domenichini A, Capone E, Damiani V, Akkaya BG, Linton KJ, Di Sebastiano P, Chen X, Keeton AB, Ramirez-Alcantara V, Maxuitenko Y, Piazza GA, De Laurenzi V, Sala G, Falasca M. Pharmacological inhibition of ABCC3 slows tumour progression in animal models of pancreatic cancer. Journal of Experimental & Clinical Cancer Research : Cr. 38: 312. PMID 31378204 DOI: 10.1186/S13046-019-1308-7 |
0.404 |
|
| 2019 |
Abd El-Aleam RH, George RF, Lee KJ, Keeton AB, Piazza GA, Kamel AA, El-Daly ME, Hassan GS, Abdel-Rahman HM. Design and synthesis of 1,2,4-triazolo[1,5-a]pyrimidine derivatives as PDE 4B inhibitors endowed with bronchodilator activity. Archiv Der Pharmazie. e1900002. PMID 31353608 DOI: 10.1002/Ardp.201900002 |
0.403 |
|
| 2019 |
Keeton AB, Ward A, Chen X, Valiyaveettil J, Zhu B, Ramirez-Alcantara V, Maxuitenko Y, Berry K, Mattox TE, Boyd MR, Piazza GA. Abstract 2707: A novel RAS inhibitor, MCI-062, inhibits colon tumor growth in vivo and activates antitumor immunity Cancer Research. 79: 2707-2707. DOI: 10.1158/1538-7445.Sabcs18-2707 |
0.524 |
|
| 2019 |
Mattox TE, Norton TS, Keeton AB, Ward AB, Maxuitenko YY, Berry KL, Zhu B, Musiyenko A, Gavin E, Ramirez-Alcantara V, Chen X, Valiyaveettil J, Scalici J, Rocconi RP, Piazza GA, et al. Abstract 4822: Targeting RAS and downstream signaling in high-grade serous ovarian carcinoma with novel RAS inhibitors Cancer Research. 79: 4822-4822. DOI: 10.1158/1538-7445.Am2019-4822 |
0.459 |
|
| 2019 |
Ward AB, Chen X, Valiyaveettil J, Lee K, Chang WL, Maxuitenko Y, Ramirez-Alcantara V, Berry K, Silva LMd, Zhu B, Mattox T, Boyd MR, Keeton AB, Clapper ML, Cooper HS, ... Piazza GA, et al. Abstract 3864: A novel PDE10/β-catenin pathway inhibitor, MCI-030, for the treatment of colorectal cancer Cancer Research. 79: 3864-3864. DOI: 10.1158/1538-7445.Am2019-3864 |
0.596 |
|
| 2019 |
Mattox TE, Chen X, Valiyaveettil J, Maxuitenko Y, Zhu B, Ward A, Ramirez-Alcantara V, Berry K, Boyd M, Keeton A, Piazza GA. Abstract 345: Novel RAS inhibitor, MCI-062, potently and selectively inhibits the growth ofKRASmutant pancreatic tumor cells by blocking GTP loading of RAS Cancer Research. 79: 345-345. DOI: 10.1158/1538-7445.Am2019-345 |
0.471 |
|
| 2019 |
Zhu B, Ramirez-Alcantara V, Ward A, Berry K, Keeton AB, Boyd MR, Maxuitenko Y, Chen X, Piazza GA. Abstract 2731: A novel PDE10/beta-catenin inhibitor, MCI-048, suppresses lung tumorigenesis to block metastasis Cancer Research. 79: 2731-2731. DOI: 10.1158/1538-7445.Am2019-2731 |
0.507 |
|
| 2019 |
da Silva LM, Berry W, Chen X, Maxuitenko Y, Piazza G, Scalici J. A novel NSAID derivative for ovarian cancer chemoprevention in the hen model Gynecologic Oncology. 154: 91. DOI: 10.1016/J.Ygyno.2019.04.215 |
0.368 |
|
| 2018 |
Eldehna WM, Al-Wabli RI, Almutairi MS, Keeton AB, Piazza GA, Abdel-Aziz HA, Attia MI. Synthesis and biological evaluation of certain hydrazonoindolin-2-one derivatives as new potent anti-proliferative agents. Journal of Enzyme Inhibition and Medicinal Chemistry. 33: 867-878. PMID 29707975 DOI: 10.1080/14756366.2018.1462802 |
0.455 |
|
| 2018 |
El-Sharkawy LY, El-Sakhawy RA, Abdel-Halim M, Lee K, Piazza GA, Ducho C, Hartmann RW, Abadi AH. Design and synthesis of novel annulated thienopyrimidines as phosphodiesterase 5 (PDE5) inhibitors. Archiv Der Pharmazie. PMID 29656464 DOI: 10.1002/Ardp.201800018 |
0.397 |
|
| 2018 |
Silva LMd, Mattox TE, Keeton AB, Zhu B, Berry KL, Musiyenko A, Gavin E, Lee K, Ramirez-Alcantara V, Maxuitenko YY, Chen X, Valiyaveettil J, Boyd MR, Scalici J, Rocconi R, ... Piazza GA, et al. Abstract B54: Targeting constitutively active RAS signaling in high-grade serous ovarian carcinoma (HGSOC) with ADT-006, a novel small molecule that blocks RAS-effector interactions Clinical Cancer Research. 24. DOI: 10.1158/1557-3265.Tcm17-B54 |
0.453 |
|
| 2018 |
Piazza GA, Neese A, Lee K, Keeton A, Maxuitenko Y, Alcantara VR, Berry K, Valiyaveettil J, Ward A, Silva LMd, Scalici J, Zhu B, Mattox T, Chen X, Clapper M, et al. Abstract 1937: Inhibition of a novel cancer target, PDE10, suppresses Wnt/β-catenin signaling and colon tumorigenesis: Benefits from combining with ornithine decarboxylase inhibitors Cancer Research. 78: 1937-1937. DOI: 10.1158/1538-7445.Am2018-1937 |
0.62 |
|
| 2018 |
Madeira da Silva L, Gavin E, Kiszla B, Rocconi R, Piazza G, Scalici J. Targeting inflammation and polyamine synthesis in epithelial ovarian cancer: PDE10 and ODC1 inhibition in c-Myc amplified disease Gynecologic Oncology. 149: 181-182. DOI: 10.1016/J.Ygyno.2018.04.413 |
0.412 |
|
| 2017 |
Zhu B, Lindsey A, Li N, Lee K, Ramirez-Alcantara V, Canzoneri JC, Fajardo A, Madeira da Silva L, Thomas M, Piazza JT, Yet L, Eberhardt BT, Gurpinar E, Otali D, Grizzle W, ... ... Piazza GA, et al. Phosphodiesterase 10A is overexpressed in lung tumor cells and inhibitors selectively suppress growth by blocking β-catenin and MAPK signaling. Oncotarget. 8: 69264-69280. PMID 29050202 DOI: 10.18632/Oncotarget.20566 |
0.504 |
|
| 2017 |
Abdel-Aziz HA, Eldehna WM, Keeton AB, Piazza GA, Kadi AA, Attwa MW, Abdelhameed AS, Attia MI. Isatin-benzoazine molecular hybrids as potential antiproliferative agents: synthesis and in vitro pharmacological profiling. Drug Design, Development and Therapy. 11: 2333-2346. PMID 28848327 DOI: 10.2147/Dddt.S140164 |
0.421 |
|
| 2017 |
Attia MI, Eldehna WM, Afifi SA, Keeton AB, Piazza GA, Abdel-Aziz HA. New hydrazonoindolin-2-ones: Synthesis, exploration of the possible anti-proliferative mechanism of action and encapsulation into PLGA microspheres. Plos One. 12: e0181241. PMID 28742842 DOI: 10.1371/Journal.Pone.0181241 |
0.396 |
|
| 2017 |
Lee K, Piazza GA. The interaction between the Wnt/β-catenin signaling cascade and PKG activation in cancer. Journal of Biomedical Research. PMID 28546515 DOI: 10.7555/JBR.31.20160133 |
0.379 |
|
| 2017 |
Keeton AB, Salter EA, Piazza GA. The RAS-Effector Interaction as a Drug Target. Cancer Research. PMID 28062402 DOI: 10.1158/0008-5472.Can-16-0938 |
0.353 |
|
| 2017 |
Ramirez-Alcantara V, Keeton AB, Zhu B, Lee KJ, Canzoneri J, Lindsey AS, Barnes LMdS, Berry K, Valiyaveettil J, Chen X, Boyd MR, Piazza G. Abstract B23: DC070-547, a novel Ras inhibitor potently and selectivity inhibits colon tumor growthin vitroandin vivo Cancer Research. 77. DOI: 10.1158/1538-7445.Crc16-B23 |
0.454 |
|
| 2017 |
Lindsey AS, Lee K, Andrews J, Chang WL, Ramirez-Alcantara V, Tan M, Grizzle W, Clapper ML, Piazza G. Abstract B21: PDE10A overexpression in colon cancer cells and tumors relative to normal colonocytes and colon mucosa Cancer Research. 77. DOI: 10.1158/1538-7445.Crc16-B21 |
0.529 |
|
| 2017 |
Lee KJ, Chen X, Valiyaveettil J, Lindsey AS, Andrews J, Ramirez-Alcantara V, Keeton AB, Piazza GA, Clapper ML, Chang WL. Abstract A30: Novel non-COX inhibitory sulindac derivative with PDE10 inhibitory activity reduces incidence and multiplicity of colorectal adenomas in the APC+/min-FCCC mouse model Cancer Research. 77. DOI: 10.1158/1538-7445.Crc16-A30 |
0.547 |
|
| 2017 |
Lee KJ, Chen X, Valiyaveettil J, Lindsey AS, Andrews J, Ramirez-Alcantara V, Keeton AB, Piazza GA, Cooper H, Clapper M, Chang WL. Abstract 5243: Novel non-COX inhibitory sulindac derivative with β-catenin suppressing activity reduces the formation of colorectal adenomas and adenocarcinomas in theAPC+/min-FCCCmouse model Cancer Research. 77: 5243-5243. DOI: 10.1158/1538-7445.Am2017-5243 |
0.408 |
|
| 2017 |
Silva LMD, Gavin E, Lee KJ, Ramírez-Alcántara V, Berry KL, Taylor HT, Musiyenko A, Aragon IV, Keeton AB, Scalici J, Rocconi RP, Piazza GA. Abstract 5174: Phosphodiesterase 10A inhibition as a novel approach to suppress β-catenin signaling in ovarian cancer cells Cancer Research. 77: 5174-5174. DOI: 10.1158/1538-7445.Am2017-5174 |
0.533 |
|
| 2017 |
Saville KM, Lee K, Mattox TE, Chen X, Valiyaveettil J, Berry K, Ramírez-Alcántara V, Zhu B, Keeton A, Boyd M, Piazza G, Lindsey AS. Abstract 5166: Sensitivity of melanoma cells to a novel class of Ras inhibitors Cancer Research. 77: 5166-5166. DOI: 10.1158/1538-7445.Am2017-5166 |
0.43 |
|
| 2017 |
Mattox TE, Lee KJ, Chen X, Valiyaveettil J, Silva LMd, Lindsey AS, Keeton AB, Zhu B, Boyd M, Piazza GA. Abstract 5165: Novel RAS inhibitors DC070-547 and ADT-006 potently and selectively inhibit the growth of pancreatic tumor cells harboring constitutively activated RAS by blocking RAS-effector binding and signaling Cancer Research. 77: 5165-5165. DOI: 10.1158/1538-7445.Am2017-5165 |
0.463 |
|
| 2017 |
Ward A, Chen X, Valiyaveettil J, Zhu B, Ramirez-Alcantara V, Lee KJ, Lindsey A, Berry K, Mattox TE, McConnell K, Boyd MR, Piazza GA, Keeton AB. Abstract 5159: Characterization of a novel class of RAS inhibitory compounds with potent anti-tumor activity Cancer Research. 77: 5159-5159. DOI: 10.1158/1538-7445.Am2017-5159 |
0.481 |
|
| 2017 |
Zhu B, Chen X, Valiyaveettil J, Canzoneri J, Lee K, Saville K, Berry K, Barnes L, Maddox T, Lindsey A, Ward A, Ramirez-Alcantara V, Keeton A, Boyd M, Piazza G. Abstract 4972: Novel Ras inhibitor DC070-547 potently and selectively blocks Ras-RBD binding, EGFR binding to Ras signaling complex, EGFR activation of Ras signaling, and growth of Ras-driven lung tumor cells Cancer Research. 77: 4972-4972. DOI: 10.1158/1538-7445.Am2017-4972 |
0.409 |
|
| 2017 |
Ramirez-Alcantara V, Zhu B, Chen X, Savai R, Subbarayal P, Schuler MA, Lee KJ, Lindsey AS, Berry KL, Otali D, Canzoneri J, Valiyaveettil J, Keeton A, Coward L, Gorman G, ... ... Piazza GA, et al. Abstract 1140: Characterization of a novel PDE10 inhibitor in lung tumor cells and an orthotopic mouse model of lung cancer Cancer Research. 77: 1140-1140. DOI: 10.1158/1538-7445.Am2017-1140 |
0.512 |
|
| 2016 |
Whitt JD, Keeton AB, Gary BD, Sklar LA, Sodani K, Chen ZS, Piazza GA. Sulindac sulfide selectively increases sensitivity of ABCC1 expressing tumor cells to doxorubicin and glutathione depletion. Journal of Biomedical Research. 30: 120-133. PMID 28276667 DOI: 10.7555/Jbr.30.20150108 |
0.429 |
|
| 2016 |
Chung WJ, Goeckeler-Fried JL, Havasi V, Chiang A, Rowe SM, Plyler ZE, Hong JS, Mazur M, Piazza GA, Keeton AB, White EL, Rasmussen L, Weissman AM, Denny RA, Brodsky JL, et al. Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics. Plos One. 11: e0163615. PMID 27732613 DOI: 10.1371/Journal.Pone.0163615 |
0.35 |
|
| 2016 |
Prasain JK, Rajbhandari R, Keeton AB, Piazza GA, Barnes S. Metabolism and growth inhibitory activity of cranberry derived flavonoids in bladder cancer cells. Food & Function. 7: 4012-4019. PMID 27711848 DOI: 10.1039/C6Fo00499G |
0.454 |
|
| 2016 |
Lim S, Liu H, da Silva LM, Arora R, Liu Z, Phillips JB, Schmitt DC, Vu T, McClellan S, Lin Y, Lin W, Piazza GA, Fodstad O, Tan M. Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1α. Cancer Research. 76: 2231-2242. PMID 27197253 DOI: 10.1158/0008-5472.Can-15-1538 |
0.362 |
|
| 2016 |
Yi B, Chang H, Ma R, Feng X, Li W, Piazza GA, Xi Y. Inhibition of breast cancer cell motility with a non-cyclooxygenase inhibitory derivative of sulindac by suppressing TGFβ/miR-21 signaling. Oncotarget. PMID 26769851 DOI: 10.18632/Oncotarget.6888 |
0.531 |
|
| 2016 |
Rezk MS, Abdel-Halim M, Keeton A, Franklin D, Bauer M, Boeckler FM, Engel M, Hartmann RW, Zhang Y, Piazza GA, Abadi AH. Synthesis and Optimization of New 3,6-Disubstitutedindole Derivatives and Their Evaluation as Anticancer Agents Targeting the MDM2/MDMx Complex. Chemical & Pharmaceutical Bulletin. 64: 34-41. PMID 26726742 DOI: 10.1248/Cpb.C15-00608 |
0.446 |
|
| 2016 |
Abdel-Rahman HM, Abdel-Aziz M, Tinsley HN, Gary BD, Canzoneri JC, Piazza GA. Design and Synthesis of Substituted Pyridazinone-1-Acetylhydrazones as Novel Phosphodiesterase 4 Inhibitors. Archiv Der Pharmazie. 349: 104-11. PMID 26686665 DOI: 10.1002/Ardp.201500363 |
0.744 |
|
| 2016 |
Whitt JD, Keeton AB, Gary BD, Sklar LA, Sodani K, Chen ZS, Piazza GA. Sulindac sulfide selectively increases sensitivity of ABCC1 expressing tumor cells to doxorubicin and glutathione depletion Journal of Biomedical Research. 30: 120-133. DOI: 10.7555/JBR.30.20150108 |
0.317 |
|
| 2016 |
Silva LMd, Gavin E, Lee K, Aragon I, Ramírez-Alcántara V, Scalici J, Rocconi RP, Piazza GA. Abstract A76: Targeting phosphodiesterase 10A for chemoprevention and treatment of ovarian cancer. Clinical Cancer Research. 22. DOI: 10.1158/1557-3265.Ovca15-A76 |
0.53 |
|
| 2016 |
Yi B, Chang H, Feng X, Ma R, Piazza GA, Xi Y. Abstract B34: Inhibition of breast cancer cell metastasis with a non-cyclooxygenase inhibitory derivative of sulindac by suppressing TGFbeta/miR-21 signaling Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Cellcycle16-B34 |
0.496 |
|
| 2016 |
Lindsey AS, Lee K, Zhu B, Arora R, Otali D, Ramirez-Alacantara V, Grizzle W, Piazza G. Abstract 4736: PDE10A overexpression in cancer cells and tumors as compared to normal cells and tissues Cancer Research. 76: 4736-4736. DOI: 10.1158/1538-7445.Am2016-4736 |
0.436 |
|
| 2016 |
Lee KJ, Lindsey AS, Silva LMd, Trinh A, Gary B, Andrews J, Ramirez-Alcantara V, Keeton AB, Chang W, Clapper M, Piazza GA. Abstract 331: Beta-catenin nuclear translocation in colorectal cancer cells is suppressed by PDE10A inhibition, cGMP elevation, and activation of PKG Cancer Research. 76: 331-331. DOI: 10.1158/1538-7445.Am2016-331 |
0.61 |
|
| 2016 |
Keeton AB, Zhu B, Lee KJ, Canzoneri JC, Sigler SC, Lindsey AS, Ramirez-Alcantara V, Barnes L, Mattox TE, McConnell K, Berry KL, Valiyaveettil J, Chen X, Boyd MR, Piazza GA. Abstract 326: Discovery and in vitro and in vivo characterization of a novel, small-molecule Ras inhibitor class Cancer Research. 76: 326-326. DOI: 10.1158/1538-7445.Am2016-326 |
0.443 |
|
| 2016 |
Zhu B, Chen X, Ramirez-Alcantara V, Lee K, Valiyaveettil J, Canzoneri J, Sigler S, Berry K, Lindsey A, Keeton A, Boyd MR, Piazza GA. Abstract 1238: A novel Ras inhibitor potently and selectively suppresses lung tumor cell growth by blocking Ras-Raf binding Cancer Research. 76: 1238-1238. DOI: 10.1158/1538-7445.Am2016-1238 |
0.424 |
|
| 2016 |
Prasain JK, Rajbhandari R, Keeton AB, Piazza GA, Barnes S. Metabolism and growth inhibitory activity of cranberry derived flavonoids in bladder cancer cells Food and Function. 7: 4012-4019. DOI: 10.1039/c6fo00499g |
0.35 |
|
| 2015 |
Elhady AK, Sigler SC, Noureldin N, Canzoneri JC, Ahmed NS, Piazza GA, Abadi AH. Structure-Based Design of Novel Tetrahydro-Beta-Carboline Derivatives with a Hydrophilic Side Chain as Potential Phosphodiesterase Inhibitors. Scientia Pharmaceutica. 84: 428-446. PMID 28117310 DOI: 10.3390/Scipharm84030428 |
0.331 |
|
| 2015 |
Lee K, Lindsey AS, Li N, Gary B, Andrews J, Keeton AB, Piazza GA. β-catenin nuclear translocation in colorectal cancer cells is suppressed by PDE10A inhibition, cGMP elevation, and activation of PKG. Oncotarget. PMID 26713600 DOI: 10.18632/Oncotarget.6705 |
0.597 |
|
| 2015 |
Somasagara RR, Tripathi K, Spencer SM, Clark DW, Barnett R, Bachaboina L, Scalici J, Rocconi RP, Piazza GA, Palle K. Rad6 upregulation promotes stem cell-like characteristics and platinum resistance in ovarian cancer. Biochemical and Biophysical Research Communications. PMID 26679603 DOI: 10.1016/J.Bbrc.2015.11.134 |
0.433 |
|
| 2015 |
Hassaan EA, Sigler SC, Ibrahim TM, Lee KJ, Cichon LK, Gary BD, Canzoneri JC, Piazza GA, Abadi AH. Mining ZINC Database to Discover Potential Phosphodiesterase 9 Inhibitors Using Structure-Based Drug Design Approach. Medicinal Chemistry (Shariqah (United Arab Emirates)). PMID 26648332 DOI: 10.2174/1573406412666151204002836 |
0.529 |
|
| 2015 |
Li N, Chen X, Zhu B, Ramírez-Alcántara V, Canzoneri JC, Lee K, Sigler S, Gary B, Li Y, Zhang W, Moyer MP, Salter EA, Wierzbicki A, Keeton AB, Piazza GA. Suppression of β-catenin/TCF transcriptional activity and colon tumor cell growth by dual inhibition of PDE5 and 10. Oncotarget. PMID 26299804 DOI: 10.18632/Oncotarget.4741 |
0.626 |
|
| 2015 |
Ma R, Yi B, Piazza GA, Xi Y. Mechanistic Role of MicroRNA in Cancer Chemoprevention by Nonsteroidal Anti-inflammatory Drugs. Current Pharmacology Reports. 1: 154-160. PMID 26213681 DOI: 10.1007/S40495-014-0011-9 |
0.421 |
|
| 2015 |
Fajardo AM, Piazza GA. Chemoprevention in gastrointestinal physiology and disease. Anti-inflammatory approaches for colorectal cancer chemoprevention. American Journal of Physiology. Gastrointestinal and Liver Physiology. 309: G59-70. PMID 26021807 DOI: 10.1152/Ajpgi.00101.2014 |
0.418 |
|
| 2015 |
Tripathi K, Hussein UK, Anupalli R, Barnett R, Bachaboina L, Scalici J, Rocconi RP, Owen LB, Piazza GA, Palle K. Allyl isothiocyanate induces replication-associated DNA damage response in NSCLC cells and sensitizes to ionizing radiation. Oncotarget. 6: 5237-52. PMID 25742788 DOI: 10.18632/Oncotarget.3026 |
0.396 |
|
| 2015 |
Li N, Lee K, Xi Y, Zhu B, Gary BD, Ramírez-Alcántara V, Gurpinar E, Canzoneri JC, Fajardo A, Sigler S, Piazza JT, Chen X, Andrews J, Thomas M, Lu W, ... ... Piazza GA, et al. Phosphodiesterase 10A: a novel target for selective inhibition of colon tumor cell growth and β-catenin-dependent TCF transcriptional activity. Oncogene. 34: 1499-509. PMID 24704829 DOI: 10.1038/Onc.2014.94 |
0.562 |
|
| 2015 |
Li N, Chen X, Zhu B, Ramírez-Alcántara V, Canzoneri JC, Lee K, Sigler S, Gary B, Li Y, Zhang W, Moyer MP, Salter EA, Wierzbicki A, Keeton AB, Piazza GA. Suppression of ß-catenin/TCF transcriptional activity and colon tumor cell growth by dual inhibition of PDE5 and 10 Oncotarget. 6: 27403-27415. DOI: 10.18632/oncotarget.4741 |
0.546 |
|
| 2015 |
Silva LMd, Lee K, Piazza GA, Bachaboina L, Rocconi RP, Scalici J. Abstract POSTER-BIOL-1336: Investigating the role of phosphodiesterase 10A as a novel target in ovarian cancer Clinical Cancer Research. 21. DOI: 10.1158/1557-3265.Ovcasymp14-Poster-Biol-1336 |
0.488 |
|
| 2015 |
Yi B, Feng X, Chang H, Ma R, Zhang X, Piazza GA, Xi Y. Abstract P1-07-25: SSA, a novel sulindac sulfide derivative, inhibits tumor cell growth and invasion in breast cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P1-07-25 |
0.491 |
|
| 2015 |
Ramirez-Alcantara V, Schuler M, Zhu B, Li N, Gurpinar E, Otali D, Canzoneri J, Keeton A, Gary B, Russo S, Coward L, Gorman G, Grizzle W, Chen X, Boyd M, ... Piazza G, et al. Abstract 950: Antitumor activity of a novel phosphodiesterase 10 inhibitor in an orthotopic mouse model of lung cancer Cancer Research. 75: 950-950. DOI: 10.1158/1538-7445.Am2015-950 |
0.507 |
|
| 2015 |
Canzoneri JC, Chen X, Keeton AB, Lee K, Gary B, Butler EB, Grizzle WE, Wilson L, Barnes S, Boyd MR, Piazza GA. Abstract 701: A novel class of Ras selective inhibitors Cancer Research. 75: 701-701. DOI: 10.1158/1538-7445.Am2015-701 |
0.469 |
|
| 2015 |
Zhu B, Lee K, Canzoneri J, Ramirez-Alcantara V, Sigler S, Gary B, Butler E, Keeton A, Chen X, Boyd M, Piazza G. Abstract 4372: Phosphodiesterase 10A inhibition suppresses lung tumor cell growth by activating PKG to inhibit ras and Wnt signaling Cancer Research. 75: 4372-4372. DOI: 10.1158/1538-7445.Am2015-4372 |
0.571 |
|
| 2015 |
Lee K, Li N, Chen X, Zhu B, Yet L, Silva LMd, Russo S, Keeton AB, Boyd MR, Piazza GA. Abstract 4360: Validation of phosphodiesterase 10A as a cancer target Cancer Research. 75: 4360-4360. DOI: 10.1158/1538-7445.Am2015-4360 |
0.618 |
|
| 2015 |
Yi B, Feng X, Ma R, Zhang X, Chang H, Zhao H, Liang Z, Chen X, Hu X, Piazza G, Xi Y. Abstract 4125: SSA, a novel sulindac derivative, inhibits breast cancer cell invasion and migration Cancer Research. 75: 4125-4125. DOI: 10.1158/1538-7445.Am2015-4125 |
0.433 |
|
| 2015 |
Sigler SC, Ramirez-Alcantara V, Keeton AB, Abdel-Halim M, Abadi AH, Piazza GA. Abstract 1914: A novel celecoxib derivative that lacks COX-2 inhibition but displays potent colon tumor cell growth and PDE5 inhibitory activity Cancer Research. 75: 1914-1914. DOI: 10.1158/1538-7445.Am2015-1914 |
0.587 |
|
| 2015 |
Piazza GA, Zhu B, Lee K, Canzoneri J, Sigler S, Lindsey A, Ramirez-Alcantara V, Silva LMd, Mullins H, Trinh A, Berry K, Valiyaveettil J, Keeton AB, Chen X, Boyd MR. Abstract A140: Novel drug development candidate potently and selectively inhibits growth of tumor cells harboring activated Ras Molecular Cancer Therapeutics. 14. DOI: 10.1158/1535-7163.Targ-15-A140 |
0.465 |
|
| 2015 |
da Silva L, Lee K, Piazza G, Bachaboina L, Rocconi R, Scalici J. Investigating the role of phosphodiesterase 10A as a novel target in ovarian cancer Gynecologic Oncology. 137: 208-209. DOI: 10.1016/J.Ygyno.2015.01.553 |
0.339 |
|
| 2014 |
Aboul-Fadl T, Al-Hamad SS, Lee K, Li N, Gary BD, Keeton AB, Piazza GA, Abdel-Hamid MK. Novel non-cyclooxygenase inhibitory derivatives of naproxen for colorectal cancer chemoprevention. Medicinal Chemistry Research : An International Journal For Rapid Communications On Design and Mechanisms of Action of Biologically Active Agents. 23: 4177-4188. PMID 27559271 DOI: 10.1007/S00044-014-0979-Z |
0.549 |
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| 2014 |
Abdel-Rahman HM, Abdel-Aziz M, Canzoneri JC, Gary BD, Piazza GA. Novel quinazolin-4(3H)-one/Schiff base hybrids as antiproliferative and phosphodiesterase 4 inhibitors: design, synthesis, and docking studies. Archiv Der Pharmazie. 347: 650-7. PMID 24985336 DOI: 10.1002/Ardp.201400083 |
0.514 |
|
| 2014 |
Arora R, Yates C, Gary BD, McClellan S, Tan M, Xi Y, Reed E, Piazza GA, Owen LB, Dean-Colomb W. Panepoxydone targets NF-kB and FOXM1 to inhibit proliferation, induce apoptosis and reverse epithelial to mesenchymal transition in breast cancer. Plos One. 9: e98370. PMID 24896091 DOI: 10.1371/Journal.Pone.0098370 |
0.443 |
|
| 2014 |
Koneczny I, Schulenburg A, Hudec X, Knöfler M, Holzmann K, Piazza G, Reynolds R, Valent P, Marian B. Autocrine fibroblast growth factor 18 signaling mediates Wnt-dependent stimulation of CD44-positive human colorectal adenoma cells. Molecular Carcinogenesis. PMID 24619956 DOI: 10.1002/Mc.22146 |
0.418 |
|
| 2014 |
Fajardo AM, Piazza GA, Tinsley HN. The role of cyclic nucleotide signaling pathways in cancer: targets for prevention and treatment. Cancers. 6: 436-58. PMID 24577242 DOI: 10.3390/Cancers6010436 |
0.742 |
|
| 2014 |
Gurpinar E, Grizzle WE, Piazza GA. NSAIDs inhibit tumorigenesis, but how? Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 1104-13. PMID 24311630 DOI: 10.1158/1078-0432.Ccr-13-1573 |
0.57 |
|
| 2014 |
Russo S, Li N, Lee K, Xi Y, Zhu B, Gary B, Ramirez V, Gurpinar E, Canzeroni J, Fajardo A, Sigler S, Piazza JT, Chen X, Andrews J, Li Y, ... ... Piazza G, et al. Phosphodiesterase 10, a novel target in colon cancer. Journal of Clinical Oncology. 32: 503-503. DOI: 10.1200/Jco.2014.32.3_Suppl.503 |
0.569 |
|
| 2014 |
Russo SM, Ramirez-Alcantara V, Schuler M, Zhu B, Li N, Canzoneri J, Keeton A, Grizzle WE, Chen X, Piazza G. PDE10 inhibitors suppress lung tumor growth in mice. Journal of Clinical Oncology. 32: e22187-e22187. DOI: 10.1200/Jco.2014.32.15_Suppl.E22187 |
0.454 |
|
| 2014 |
Chen X, Lee KJ, Gary BD, Canzoneri JC, Fajardo AM, Sigler SC, Ramirez-Alcantara V, Zhu B, Piazza GA, Keeton AB. Abstract B39: A novel series of substituted indene derivatives that potently and selectively inhibit growth of tumor cells harboring mutant Ras Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Rasonc14-B39 |
0.477 |
|
| 2014 |
Fajardo AM, Gary BD, Lee KJ, Keeton AB, Zhu B, Chen X, Abadi AH, Piazza GA. Abstract 2322: β-catenin-dependent TCF/LEF transcriptional regulation of phosphodiesterase expression in colon cancer cells Cancer Research. 74: 2322-2322. DOI: 10.1158/1538-7445.Am2014-2322 |
0.5 |
|
| 2014 |
Li N, Lee K, Xi Y, Zhu B, Gary BD, Ramírez-Alcántara V, Gurpinar E, Canzoneri JC, Fajardo A, Sigler S, Piazza JT, Chen X, Andrews J, Lu W, Li Y, ... ... Piazza GA, et al. Abstract 1773: Phosphodiesterase 10A: A novel target for selective inhibition of colon tumor cell growth and Wnt/β-catenin signaling Cancer Research. 74: 1773-1773. DOI: 10.1158/1538-7445.Am2014-1773 |
0.582 |
|
| 2014 |
Ramirez-Alcantara V, Schuler MA, Zhu B, Li N, Gurpinar E, Canzoneri J, Keeton A, Gary B, Russo S, Coward L, Gorman GS, Grizzle W, Chen X, Piazza GA. Abstract 1768: A novel PDE10 inhibitor suppresses tumor growth in an orthotopic mouse model of lung cancer Cancer Research. 74: 1768-1768. DOI: 10.1158/1538-7445.Am2014-1768 |
0.448 |
|
| 2014 |
Lee KJ, Li N, Chen X, Zhu B, Yet L, Piazza G. Abstract 1762: Phosphodiesterase 10, a novel target for colorectal cancer therapeutics Cancer Research. 74: 1762-1762. DOI: 10.1158/1538-7445.Am2014-1762 |
0.592 |
|
| 2014 |
Zhu B, Li N, Ramirez-Alcantara V, Canzoneri J, Gurpinar E, Fajardo A, Lee K, Sigler S, Gary B, Thomas M, Keeton A, Chen X, Grizzle W, Piazza G. Abstract 1761: PDE10, a novel therapeutic target for lung cancer Cancer Research. 74: 1761-1761. DOI: 10.1158/1538-7445.Am2014-1761 |
0.445 |
|
| 2014 |
Yi B, Ma R, Feng X, Xing Z, Zhang X, Piazza G, Xi Y. Abstract 1456: MicroRNA improves the efficacy of imatinib on the treatment of chronic myeloid leukemia Cancer Research. 74: 1456-1456. DOI: 10.1158/1538-7445.Am2014-1456 |
0.426 |
|
| 2014 |
Sigler SC, Ramirez V, Abadi A, Piazza G. Abstract 1243: A novel series of celecoxib derivatives lacking COX-2 inhibitory activity more potently inhibits cancer cell growth by inhibiting PDE5 Cancer Research. 74: 1243-1243. DOI: 10.1158/1538-7445.Am2014-1243 |
0.628 |
|
| 2014 |
Aboul-Fadl T, Al-Hamad SS, Lee K, Li N, Gary BD, Keeton AB, Piazza GA, Abdel-Hamid MK. Novel non-cyclooxygenase inhibitory derivatives of naproxen for colorectal cancer chemoprevention Medicinal Chemistry Research. DOI: 10.1007/s00044-014-0979-z |
0.455 |
|
| 2013 |
Awadallah FM, Piazza GA, Gary BD, Keeton AB, Canzoneri JC. Synthesis of some dihydropyrimidine-based compounds bearing pyrazoline moiety and evaluation of their antiproliferative activity. European Journal of Medicinal Chemistry. 70: 273-9. PMID 24161704 DOI: 10.1016/J.Ejmech.2013.10.003 |
0.378 |
|
| 2013 |
Abdel-Halim M, Keeton AB, Gurpinar E, Gary BD, Vogel SM, Engel M, Piazza GA, Boeckler FM, Hartmann RW, Abadi AH. Trisubstituted and tetrasubstituted pyrazolines as a novel class of cell-growth inhibitors in tumor cells with wild type p53. Bioorganic & Medicinal Chemistry. 21: 7343-56. PMID 24139845 DOI: 10.1016/J.Bmc.2013.09.055 |
0.466 |
|
| 2013 |
Wang ZM, Du WJ, Piazza GA, Xi Y. MicroRNAs are involved in the self-renewal and differentiation of cancer stem cells. Acta Pharmacologica Sinica. 34: 1374-80. PMID 24122008 DOI: 10.1038/Aps.2013.134 |
0.338 |
|
| 2013 |
Gurpinar E, Grizzle WE, Piazza GA. COX-Independent Mechanisms of Cancer Chemoprevention by Anti-Inflammatory Drugs. Frontiers in Oncology. 3: 181. PMID 23875171 DOI: 10.3389/Fonc.2013.00181 |
0.517 |
|
| 2013 |
Hamed MM, Abou El Ella DA, Keeton AB, Piazza GA, Abadi AH, Hartmann RW, Engel M. 6-Aryl and heterocycle quinazoline derivatives as potent EGFR inhibitors with improved activity toward gefitinib-sensitive and -resistant tumor cell lines. Chemmedchem. 8: 1495-504. PMID 23847159 DOI: 10.1002/Cmdc.201300147 |
0.456 |
|
| 2013 |
Li N, Xi Y, Tinsley HN, Gurpinar E, Gary BD, Zhu B, Li Y, Chen X, Keeton AB, Abadi AH, Moyer MP, Grizzle WE, Chang WC, Clapper ML, Piazza GA. Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/β-catenin signaling. Molecular Cancer Therapeutics. 12: 1848-59. PMID 23804703 DOI: 10.1158/1535-7163.Mct-13-0048 |
0.821 |
|
| 2013 |
Arora S, Bhardwaj A, Singh S, Srivastava SK, McClellan S, Nirodi CS, Piazza GA, Grizzle WE, Owen LB, Singh AP. An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor κB- and hypoxia-inducible factor 1α-mediated up-regulation of CXCR4. The Journal of Biological Chemistry. 288: 21197-207. PMID 23740244 DOI: 10.1074/Jbc.M113.484576 |
0.375 |
|
| 2013 |
Arafa RK, Hegazy GH, Piazza GA, Abadi AH. Synthesis and in vitro antiproliferative effect of novel quinoline-based potential anticancer agents. European Journal of Medicinal Chemistry. 63: 826-32. PMID 23584545 DOI: 10.1016/J.Ejmech.2013.03.008 |
0.431 |
|
| 2013 |
Abadi AH, Hany MS, Elsharif SA, Eissa AA, Gary BD, Tinsley HN, Piazza GA. Modulating the cyclic guanosine monophosphate substrate selectivity of the phosphodiesterase 3 inhibitors by pyridine, pyrido[2,3-d]pyrimidine derivatives and their effects upon the growth of HT-29 cancer cell line. Chemical & Pharmaceutical Bulletin. 61: 405-10. PMID 23546000 DOI: 10.1248/Cpb.C12-00993 |
0.742 |
|
| 2013 |
Yi B, Piazza GA, Su X, Xi Y. MicroRNA and cancer chemoprevention. Cancer Prevention Research (Philadelphia, Pa.). 6: 401-9. PMID 23531448 DOI: 10.1158/1940-6207.Capr-13-0032 |
0.318 |
|
| 2013 |
Gurpinar E, Grizzle WE, Shacka JJ, Mader BJ, Li N, Piazza NA, Russo S, Keeton AB, Piazza GA. A novel sulindac derivative inhibits lung adenocarcinoma cell growth through suppression of Akt/mTOR signaling and induction of autophagy. Molecular Cancer Therapeutics. 12: 663-74. PMID 23443799 DOI: 10.1158/1535-7163.Mct-12-0785 |
0.566 |
|
| 2013 |
Shen G, Li X, Jia YF, Piazza GA, Xi Y. Hypoxia-regulated microRNAs in human cancer. Acta Pharmacologica Sinica. 34: 336-41. PMID 23377548 DOI: 10.1038/Aps.2012.195 |
0.438 |
|
| 2013 |
El-Gamil DS, Ahmed NS, Gary BD, Piazza GA, Engel M, Hartmann RW, Abadi AH. Design of novel β-carboline derivatives with pendant 5-bromothienyl and their evaluation as phosphodiesterase-5 inhibitors. Archiv Der Pharmazie. 346: 23-33. PMID 23307609 DOI: 10.1002/Ardp.201200334 |
0.431 |
|
| 2013 |
White MC, Johnson GG, Zhang W, Hobrath JV, Piazza GA, Grimaldi M. Sulindac sulfide inhibits sarcoendoplasmic reticulum Ca2+ ATPase, induces endoplasmic reticulum stress response, and exerts toxicity in glioma cells: relevant similarities to and important differences from celecoxib. Journal of Neuroscience Research. 91: 393-406. PMID 23280445 DOI: 10.1002/Jnr.23169 |
0.325 |
|
| 2013 |
Tinsley HN, Grizzle WE, Abadi A, Keeton A, Zhu B, Xi Y, Piazza GA. New NSAID targets and derivatives for colorectal cancer chemoprevention. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. ProgrèS Dans Les Recherches Sur Le Cancer. 191: 105-20. PMID 22893202 DOI: 10.1007/978-3-642-30331-9_6 |
0.782 |
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| 2013 |
Gurpinar E, Grizzle WE, Shacka JJ, Li N, Keeton AB, Piazza GA. Abstract 587: A novel non-COX-inhibitory sulindac derivative induces autophagic cell death by inhibiting Akt signaling in lung cancer cells. Cancer Research. 73: 587-587. DOI: 10.1158/1538-7445.Am2013-587 |
0.556 |
|
| 2013 |
Arora R, Gary BD, McClellan S, Xi Y, Piazza G, Reed E, Owen L, Dean-Colomb W. Abstract 5571: Antitumor activity of a novel natural therapeutic agent against triple negative breast cancer. Cancer Research. 73: 5571-5571. DOI: 10.1158/1538-7445.Am2013-5571 |
0.484 |
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| 2013 |
Li N, Xi Y, Tinsley HN, Gurpinar E, Gary BD, Zhu B, Li Y, Keeton AB, Grizzle WE, Piazza GA. Abstract 3659: Next generation sulindac. Cancer Research. 73: 3659-3659. DOI: 10.1158/1538-7445.Am2013-3659 |
0.818 |
|
| 2013 |
Yi B, Li X, Du W, Piazza GA, Xi Y. Abstract 1848: Let-7 brings new insights into chronic myeloid leukemia therapy. Cancer Research. 73: 1848-1848. DOI: 10.1158/1538-7445.Am2013-1848 |
0.446 |
|
| 2013 |
Li N, Lee K, Xi Y, Zhu B, Gary BD, Ramirez-Alcantara V, Gurpinar E, Canzoneri J, Fajardo A, Sigler S, Piazza JT, Chen X, Andrews J, Thomas M, Lu W, ... ... Piazza GA, et al. Abstract C182: Phosphodiesterase 10: A novel cancer target. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-C182 |
0.572 |
|
| 2013 |
Hamed MM, Abou El Ella DA, Keeton AB, Piazza GA, Engel M, Hartmann RW, Abadi AH. Quinazoline and tetrahydropyridothieno[2,3-d]pyrimidine derivatives as irreversible EGFR tyrosine kinase inhibitors: Influence of the position 4 substituent Medchemcomm. 4: 1202-1207. DOI: 10.1039/C3Md00118K |
0.383 |
|
| 2012 |
Tinsley HN, Piazza GA. Novel Therapeutics: NSAIDs, Derivatives, and Phosphodiesterases. Current Colorectal Cancer Reports. 8: 325-330. PMID 23459242 DOI: 10.1007/S11888-012-0142-5 |
0.793 |
|
| 2012 |
Ahmed NS, Ali AH, El-Nashar SM, Gary BD, Fajardo AM, Tinsley HN, Piazza GA, Negri M, Abadi AH. Exploring the PDE5 H-pocket by ensemble docking and structure-based design and synthesis of novel β-carboline derivatives. European Journal of Medicinal Chemistry. 57: 329-43. PMID 23117589 DOI: 10.1016/J.Ejmech.2012.09.029 |
0.73 |
|
| 2012 |
Arora S, Singh S, Piazza GA, Contreras CM, Panyam J, Singh AP. Honokiol: A novel natural agent for cancer prevention and therapy Current Molecular Medicine. 12: 1244-1252. PMID 22834827 DOI: 10.2174/156652412803833508 |
0.415 |
|
| 2012 |
Whitt JD, Li N, Tinsley HN, Chen X, Zhang W, Li Y, Gary BD, Keeton AB, Xi Y, Abadi AH, Grizzle WE, Piazza GA. A novel sulindac derivative that potently suppresses colon tumor cell growth by inhibiting cGMP phosphodiesterase and β-catenin transcriptional activity. Cancer Prevention Research (Philadelphia, Pa.). 5: 822-33. PMID 22556201 DOI: 10.1158/1940-6207.Capr-11-0559 |
0.817 |
|
| 2012 |
Salama I, Abdel-Fattah MA, Hany MS, El-Sharif SA, El-Naggar MA, Rashied RM, Piazza GA, Abadi AH. CoMFA and CoMSIA studies of 1,2-dihydropyridine derivatives as anticancer agents. Medicinal Chemistry (ShäRiqah (United Arab Emirates)). 8: 372-83. PMID 22530888 DOI: 10.2174/157340612800786598 |
0.459 |
|
| 2012 |
Abdel-Fattah MA, El-Naggar MA, Rashied RM, Gary BD, Piazza GA, Abadi AH. Four-component synthesis of 1,2-dihydropyridine derivatives and their evaluation as anticancer agents. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 8: 392-400. PMID 22530887 DOI: 10.2174/1573406411208030392 |
0.457 |
|
| 2012 |
Li X, Gao L, Cui Q, Gary BD, Dyess DL, Taylor W, Shevde LA, Samant RS, Dean-Colomb W, Piazza GA, Xi Y. Sulindac inhibits tumor cell invasion by suppressing NF-κB-mediated transcription of microRNAs. Oncogene. 31: 4979-86. PMID 22286762 DOI: 10.1038/Onc.2011.655 |
0.423 |
|
| 2012 |
Gao L, Gao Y, Li X, Howell P, Kumar R, Su X, Vlassov AV, Piazza GA, Riker AI, Sun D, Xi Y. Aquaporins mediate the chemoresistance of human melanoma cells to arsenite. Molecular Oncology. 6: 81-7. PMID 22130551 DOI: 10.1016/J.Molonc.2011.11.001 |
0.348 |
|
| 2012 |
Piazza GA, Li N, Bernard GD, Chen X, Keeton AB, Xi Y, Zhu B, Zhang W, Fajardo A, Ramirez V, Sigler S, Lee K, Cawthon C, Gurpinar E, Brownby MA, et al. Abstract B59: Cyclic GMP phosphodiesterase: A molecular target for cancer chemoprevention Cancer Prevention Research. 5: B59-B59. DOI: 10.1158/1940-6207.Prev-12-B59 |
0.64 |
|
| 2012 |
Gurpinar E, Grizzle WE, Liu Y, Shacka JJ, Keeton AB, Piazza GA. Abstract LB-355: A novel non-COX-inhibitory sulindac derivative induces autophagic cell death in lung adenocarcinoma cells Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-355 |
0.502 |
|
| 2012 |
Li X, Gao L, Taylor W, Shevde L, Samant R, Dean-Colomb W, Piazza GA, Xi Y. Abstract LB-172: MicroRNAs mediate the inhibition of tumor cell invasion by sulindac Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Lb-172 |
0.481 |
|
| 2012 |
Tinsley HN, Gary BD, Whitt J, Zhang W, Chen X, Keeton AB, Grubbs CJ, Grizzle WE, Piazza GA. Abstract 570: Breast cancer chemopreventive activity of a novel amide derivative of sulindac involves inhibition of PDE5, activation of PKG, and attenuation of Wnt/β-catenin signaling Cancer Research. 72: 570-570. DOI: 10.1158/1538-7445.Am2012-570 |
0.809 |
|
| 2012 |
Arora S, Srivastava SK, Bhardwaj A, Singh AP, Piazza GA, Owen LB, Singh S. Abstract 1626: Honokiol inhibits IL-8 production and exerts anti-tumor effects in colon cancer cells: therapeutic and preventive implications Cancer Research. 72: 1626-1626. DOI: 10.1158/1538-7445.Am2012-1626 |
0.427 |
|
| 2011 |
Piazza GA, Tinsley HN, Gary BD, Knight MR, Li N, Tiwari KN, Zhang W, Waud WR, Coward LU, Gorman G, Keeton AB, Struck RF, Abadi AH. A novel class of mono-alkylating agents with highly potent and selective tumor cell growth inhibitory activity. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: e13523. PMID 28022698 DOI: 10.1200/Jco.2011.29.15_Suppl.E13523 |
0.779 |
|
| 2011 |
Lu W, Lin C, Roberts MJ, Waud WR, Piazza GA, Li Y. Niclosamide suppresses cancer cell growth by inducing Wnt co-receptor LRP6 degradation and inhibiting the Wnt/β-catenin pathway. Plos One. 6: e29290. PMID 22195040 DOI: 10.1371/Journal.Pone.0029290 |
0.464 |
|
| 2011 |
Tinsley HN, Gary BD, Keeton AB, Lu W, Li Y, Piazza GA. Inhibition of PDE5 by sulindac sulfide selectively induces apoptosis and attenuates oncogenic Wnt/β-catenin-mediated transcription in human breast tumor cells. Cancer Prevention Research (Philadelphia, Pa.). 4: 1275-84. PMID 21505183 DOI: 10.1158/1940-6207.Capr-11-0095 |
0.787 |
|
| 2011 |
Ahmed NS, Gary BD, Tinsley HN, Piazza GA, Laufer S, Abadi AH. Design, synthesis and structure-activity relationship of functionalized tetrahydro-β-carboline derivatives as novel PDE5 inhibitors. Archiv Der Pharmazie. 344: 149-57. PMID 21384413 DOI: 10.1002/Ardp.201000236 |
0.738 |
|
| 2011 |
Li HF, Keeton A, Vitolo M, Maddox C, Rasmussen L, Hobrath J, White EL, Park BH, Piazza GA, Kim JS, Waldman T. A high-throughput screen with isogenic PTEN+/+ and PTEN-/- cells identifies CID1340132 as a novel compound that induces apoptosis in PTEN and PIK3CA mutant human cancer cells. Journal of Biomolecular Screening. 16: 383-93. PMID 21335596 DOI: 10.1177/1087057110397357 |
0.347 |
|
| 2011 |
Mohamed HA, Girgis NM, Wilcken R, Bauer MR, Tinsley HN, Gary BD, Piazza GA, Boeckler FM, Abadi AH. Synthesis and molecular modeling of novel tetrahydro-β-carboline derivatives with phosphodiesterase 5 inhibitory and anticancer properties. Journal of Medicinal Chemistry. 54: 495-509. PMID 21189023 DOI: 10.1021/Jm100842V |
0.765 |
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| 2011 |
Whitt JD, Keeton AB, Tinsley HN, Gary BD, Li N, Mathew B, Reynolds RC, Piazza GA. Abstract 837: Novel sulindac derivatives that inhibit colon cancer growth by a COX independent mechanism involving PDE5 inhibition and the suppression of nuclear β-catenin levels Cancer Research. 71: 837-837. DOI: 10.1158/1538-7445.Am2011-837 |
0.771 |
|
| 2011 |
Gurpinar E, Sun Y, Keeton A, Tinsley H, Gary B, Butler BL, Binkowski BF, Kopelovich L, Athar M, Piazza GA. Abstract 4610: NO-NSAIDs inhibit colon tumor cell growth by a cGMP-independent mechanism Cancer Research. 71: 4610-4610. DOI: 10.1158/1538-7445.Am2011-4610 |
0.568 |
|
| 2011 |
Tinsley HN, Keeton AB, Lu W, Li Y, Piazza GA. Abstract 1853: PDE5 suppression selectively induces apoptosis of human breast tumor cells and attenuates Wnt/β-catenin mediated transcription Cancer Research. 71: 1853-1853. DOI: 10.1158/1538-7445.Am2011-1853 |
0.787 |
|
| 2010 |
Piazza GA, Keeton AB, Tinsley HN, Whitt JD, Gary BD, Mathew B, Singh R, Grizzle WE, Reynolds RC. NSAIDs: Old Drugs Reveal New Anticancer Targets. Pharmaceuticals (Basel, Switzerland). 3: 1652-1667. PMID 27713322 DOI: 10.3390/Ph3051652 |
0.793 |
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| 2010 |
Ahmed NS, Gary BD, Piazza GA, Tinsley HN, Laufer S, Abadi AH. A novel access to arylated and heteroarylated beta-carboline based PDE5 inhibitors. Medicinal Chemistry (ShāRiqah (United Arab Emirates)). 6: 374-87. PMID 21054274 DOI: 10.2174/157340610793563992 |
0.709 |
|
| 2010 |
Tinsley HN, Gary BD, Thaiparambil J, Li N, Lu W, Li Y, Maxuitenko YY, Keeton AB, Piazza GA. Colon tumor cell growth-inhibitory activity of sulindac sulfide and other nonsteroidal anti-inflammatory drugs is associated with phosphodiesterase 5 inhibition. Cancer Prevention Research (Philadelphia, Pa.). 3: 1303-13. PMID 20876730 DOI: 10.1158/1940-6207.Capr-10-0030 |
0.813 |
|
| 2010 |
Zhang Y, Zhang J, Wang L, Quealy E, Gary BD, Reynolds RC, Piazza GA, Lü J. A novel sulindac derivative lacking cyclooxygenase-inhibitory activities suppresses carcinogenesis in the transgenic adenocarcinoma of mouse prostate model. Cancer Prevention Research (Philadelphia, Pa.). 3: 885-95. PMID 20587701 DOI: 10.1158/1940-6207.CAPR-09-0273 |
0.333 |
|
| 2010 |
Abadi AH, Gary BD, Tinsley HN, Piazza GA, Abdel-Halim M. Synthesis, molecular modeling and biological evaluation of novel tadalafil analogues as phosphodiesterase 5 and colon tumor cell growth inhibitors, new stereochemical perspective. European Journal of Medicinal Chemistry. 45: 1278-86. PMID 20206015 DOI: 10.1016/J.Ejmech.2009.10.046 |
0.753 |
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| 2010 |
Abadi AH, Abouel-Ella DA, Lehmann J, Tinsley HN, Gary BD, Piazza GA, Abdel-Fattah MA. Discovery of colon tumor cell growth inhibitory agents through a combinatorial approach. European Journal of Medicinal Chemistry. 45: 90-7. PMID 19836860 DOI: 10.1016/J.Ejmech.2009.09.029 |
0.79 |
|
| 2010 |
Piazza GA, Keeton AB, Tinsley HN, Whitt JD, Gary B, Mathew B, Singh R, Grizzle WE, Reynolds RC. NSAIDs: Old drugs reveal new anticancer targets Pharmaceuticals. 3: 1652-1667. DOI: 10.3390/ph3051652 |
0.793 |
|
| 2009 |
Tinsley HN, Gary BD, Keeton AB, Zhang W, Abadi AH, Reynolds RC, Piazza GA. Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G. Molecular Cancer Therapeutics. 8: 3331-40. PMID 19996273 DOI: 10.1158/1535-7163.Mct-09-0758 |
0.793 |
|
| 2009 |
Abadi AH, Abouel-Ella DA, Ahmed NS, Gary BD, Thaiparambil JT, Tinsley HN, Keeton AB, Piazza GA. Synthesis of novel tadalafil analogues and their evaluation as phosphodiesterase inhibitors and anticancer agents. Arzneimittel-Forschung. 59: 415-21. PMID 19813465 DOI: 10.1055/S-0031-1296417 |
0.78 |
|
| 2009 |
Abadi AH, Ibrahim TM, Abouzid KM, Lehmann J, Tinsley HN, Gary BD, Piazza GA. Design, synthesis and biological evaluation of novel pyridine derivatives as anticancer agents and phosphodiesterase 3 inhibitors. Bioorganic & Medicinal Chemistry. 17: 5974-82. PMID 19628397 DOI: 10.1016/J.Bmc.2009.06.063 |
0.793 |
|
| 2009 |
Piazza GA, Keeton AB, Tinsley HN, Gary BD, Whitt JD, Mathew B, Thaiparambil J, Coward L, Gorman G, Li Y, Sani B, Hobrath JV, Maxuitenko YY, Reynolds RC. A novel sulindac derivative that does not inhibit cyclooxygenases but potently inhibits colon tumor cell growth and induces apoptosis with antitumor activity. Cancer Prevention Research (Philadelphia, Pa.). 2: 572-80. PMID 19470791 DOI: 10.1158/1940-6207.Capr-09-0001 |
0.792 |
|
| 2009 |
Lu W, Tinsley HN, Keeton A, Qu Z, Piazza GA, Li Y. Suppression of Wnt/beta-catenin signaling inhibits prostate cancer cell proliferation. European Journal of Pharmacology. 602: 8-14. PMID 19026633 DOI: 10.1016/J.Ejphar.2008.10.053 |
0.72 |
|
| 2009 |
Tinsley H, Gary B, Keeton A, Reynolds R, Piazza G. Sulindac Sulfide Selectively Induces Apoptosis of Human Breast Tumor Cells by Inhibiting PDE5A, Elevating cGMP, and Activating PKG. Cancer Research. 69: 1041-1041. DOI: 10.1158/0008-5472.Sabcs-09-1041 |
0.492 |
|
| 2008 |
Jia L, Noker PE, Piazza GA, Leuschner C, Hansel W, Gorman GS, Coward LU, Tomaszewski J. Pharmacokinetics and pharmacodynamics of Phor21-betaCG(ala), a lytic peptide conjugate. The Journal of Pharmacy and Pharmacology. 60: 1441-8. PMID 18957164 DOI: 10.1211/jpp.60.11.0004 |
0.302 |
|
| 2004 |
Kim KP, Whitehead C, Piazza G, Wargovich MJ. Combinatorial chemoprevention: efficacy of lovostatin and exisulind on the formation and progression of aberrant crypt foci. Anticancer Research. 24: 1805-11. PMID 15274359 |
0.346 |
|
| 2004 |
Basler JW, Piazza GA. Nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 selective inhibitors for prostate cancer chemoprevention. The Journal of Urology. 171: S59-62; discussion S. PMID 14713756 DOI: 10.1097/01.Ju.0000107839.06670.27 |
0.392 |
|
| 2003 |
Lim JT, Piazza GA, Pamukcu R, Thompson WJ, Weinstein IB. Exisulind and related compounds inhibit expression and function of the androgen receptor in human prostate cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 4972-82. PMID 14581372 |
0.363 |
|
| 2003 |
Joe AK, Liu H, Xiao D, Soh JW, Pinto JT, Beer DG, Piazza GA, Thompson WJ, Weinstein IB. Exisulind and CP248 induce growth inhibition and apoptosis in human esophageal adenocarcinoma and squamous carcinoma cells. Journal of Experimental Therapeutics & Oncology. 3: 83-94. PMID 12822514 DOI: 10.1046/J.1359-4117.2003.01076.X |
0.484 |
|
| 2002 |
Chan DC, Earle KA, Zhao TL, Helfrich B, Zeng C, Baron A, Whitehead CM, Piazza G, Pamukcu R, Thompson WJ, Alila H, Nelson P, Bunn PA. Exisulind in combination with docetaxel inhibits growth and metastasis of human lung cancer and prolongs survival in athymic nude rats with orthotopic lung tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 8: 904-12. PMID 11895925 |
0.383 |
|
| 2001 |
Piazza GA, Thompson WJ, Pamukcu R, Alila HW, Whitehead CM, Liu L, Fetter JR, Gresh WE, Klein-Szanto AJ, Farnell DR, Eto I, Grubbs CJ. Exisulind, a novel proapoptotic drug, inhibits rat urinary bladder tumorigenesis. Cancer Research. 61: 3961-8. PMID 11358813 |
0.429 |
|
| 2001 |
Piazza GA, Speri G, Whitehead CM, Xu S, Klein-Szanto AJ, Yip-Sneider MT, Sweeney CJ, Lloyd M, Liu L, Fetter J, Pamukcu R, Thompson WJ. Cyclic GMP phosphodiesterase (cG PDE): Overexpression in human pancreatic carcinomas and a target for selective apoptotic antineoplastic drugs Gastroenterology. 120: A140. DOI: 10.1016/S0016-5085(08)80690-7 |
0.329 |
|
| 2000 |
Lawson KR, Ignatenko NA, Piazza GA, Cui H, Gerner EW. Influence of K-ras activation on the survival responses of Caco-2 cells to the chemopreventive agents sulindac and difluoromethylornithine Cancer Epidemiology Biomarkers and Prevention. 9: 1155-1162. PMID 11097222 |
0.323 |
|
| 2000 |
Soh JW, Mao Y, Kim MG, Pamukcu R, Li H, Piazza GA, Thompson WJ, Weinstein IB. Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of c-Jun NH2-terminal kinase 1. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 6: 4136-41. PMID 11051267 |
0.343 |
|
| 2000 |
Thompson WJ, Piazza GA, Li H, Liu L, Fetter J, Zhu B, Sperl G, Ahnen D, Pamukcu R. Exisulind induction of apoptosis involves guanosine 3',5'-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin. Cancer Research. 60: 3338-42. PMID 10910034 |
0.437 |
|
| 2000 |
Thompson WJ, Liu L, Li H, Fetter J, Sperl G, Piazza GA, Pamukcu R. Exisulind induces apoptosis in colonic tumor cells lacking APC mutations by cyclic GMP mediated B-catenin reduction Gastroenterology. 118: A670. DOI: 10.1016/S0016-5085(00)84817-9 |
0.414 |
|
| 2000 |
Piazza GA, Xu S, Klein-Szanto A, Ahnen DJ, Li H, Liu L, David M, Pamukcu R, Thompson WJ. Overexpression of CGMP phosphodiesterase (cG PDE) in colonic neoplasias compared to normal mucosa Gastroenterology. 118: A282. DOI: 10.1016/S0016-5085(00)83210-2 |
0.309 |
|
| 1999 |
Lim JT, Piazza GA, Han EK, Delohery TM, Li H, Finn TS, Buttyan R, Yamamoto H, Sperl GJ, Brendel K, Gross PH, Pamukcu R, Weinstein IB. Sulindac derivatives inhibit growth and induce apoptosis in human prostate cancer cell lines. Biochemical Pharmacology. 58: 1097-107. PMID 10484067 DOI: 10.1016/S0006-2952(99)00200-2 |
0.494 |
|
| 1999 |
Goluboff ET, Shabsigh A, Saidi JA, Weinstein IB, Mitra N, Heitjan D, Piazza GA, Pamukcu R, Buttyan R, Olsson CA. Exisulind (sulindac sulfone) suppresses growth of human prostate cancer in a nude mouse xenograft model by increasing apoptosis. Urology. 53: 440-5. PMID 9933075 DOI: 10.1016/S0090-4295(98)00513-5 |
0.416 |
|
| 1998 |
Skopińska-Rózewska E, Piazza GA, Sommer E, Pamukcu R, Barcz E, Filewska M, Kupis W, Caban R, Rudziński P, Bogdan J, Mlekodaj S, Sikorska E. Inhibition of angiogenesis by sulindac and its sulfone metabolite (FGN- 1): A potential mechanism for their antineoplastic properties International Journal of Tissue Reactions. 20: 85-89. PMID 9894180 |
0.41 |
|
| 1998 |
Han EK, Arber N, Yamamoto H, Lim JT, Delohery T, Pamukcu R, Piazza GA, Xing WQ, Weinstein IB. Effects of sulindac and its metabolites on growth and apoptosis in human mammary epithelial and breast carcinoma cell lines. Breast Cancer Research and Treatment. 48: 195-203. PMID 9598866 DOI: 10.1023/A:1005924730450 |
0.496 |
|
| 1998 |
Kelloff J, Maltzman T, Piazza G, Ahnen D. NSAIDs may reactivate the adenomatous polyposis coli (APC) pathway to apoptosis Gastroenterology. 114: A620. DOI: 10.1016/S0016-5085(98)82534-1 |
0.31 |
|
| 1998 |
Harris N, Kaznov D, Pick M, Deutsch V, Paweletz N, Schroeter D, Piazza G, Ahnen D, Pamukcu R, Holt P, Weinstein I, Arber N. c-K-ras transformed rat enterocytes (R1) are more sensitive than normal enterocytes (IEC18) to growth inhibition and appptosis-induced by sulindac sulfone and nimesulid Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)82478-5 |
0.313 |
|
| 1997 |
Piazza GA, Rahm AK, Finn TS, Fryer BH, Li H, Stoumen AL, Pamukcu R, Ahnen DJ. Apoptosis primarily accounts for the growth-inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest, and p53 induction Cancer Research. 57: 2452-2459. PMID 9192825 |
0.388 |
|
| 1997 |
Thompson HJ, Jiang C, Lu J, Mehta RG, Piazza GA, Paranka NS, Pamukcu R, Ahnen DJ. Sulfone metabolite of sulindac inhibits mammary carcinogenesis. Cancer Research. 57: 267-71. PMID 9000566 |
0.398 |
|
| 1995 |
Piazza GA, Rahm AL, Krutzsch M, Sperl G, Paranka NS, Gross PH, Brendel K, Burt RW, Alberts DS, Pamukcu R. Antineoplastic drugs sulindac sulfide and sulfone inhibit cell growth by inducing apoptosis. Cancer Research. 55: 3110-6. PMID 7606732 |
0.436 |
|
| 1995 |
Ahnen D, Piazza G, Alberts D, Paranka N, Burt R, Pamukcu R. Sulindac sulfide (SS) and sulfone (FGN-1) both inhibit the growth of colon cancer cell lines by inducing apoptosis Gastroenterology. 108: A443. DOI: 10.1016/0016-5085(95)26088-9 |
0.482 |
|
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