Year |
Citation |
Score |
2023 |
Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, Andrews DW, Aqeilan RI, Arama E, Baehrecke EH, ... ... Degterev A, et al. Apoptotic cell death in disease-Current understanding of the NCCD 2023. Cell Death and Differentiation. PMID 37100955 DOI: 10.1038/s41418-023-01153-w |
0.34 |
|
2023 |
Johnson JL, Yaron TM, Huntsman EM, Kerelsky A, Song J, Regev A, Lin TY, Liberatore K, Cizin DM, Cohen BM, Vasan N, Ma Y, Krismer K, Robles JT, van de Kooij B, ... ... Degterev A, et al. An atlas of substrate specificities for the human serine/threonine kinome. Nature. PMID 36631611 DOI: 10.1038/s41586-022-05575-3 |
0.321 |
|
2021 |
Delanghe T, Huyghe J, Lee S, Priem D, Van Coillie S, Gilbert B, Choi SM, Vandenabeele P, Degterev A, Cuny GD, Dondelinger Y, Bertrand MJM. Antioxidant and food additive BHA prevents TNF cytotoxicity by acting as a direct RIPK1 inhibitor. Cell Death & Disease. 12: 699. PMID 34262020 DOI: 10.1038/s41419-021-03994-0 |
0.415 |
|
2021 |
Zelic M, Pontarelli F, Woodworth L, Zhu C, Mahan A, Ren Y, LaMorte M, Gruber R, Keane A, Loring P, Guo L, Xia TH, Zhang B, Orning P, Lien E, ... Degterev A, et al. RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis. Cell Reports. 35: 109112. PMID 33979622 DOI: 10.1016/j.celrep.2021.109112 |
0.334 |
|
2021 |
Nikhar S, Siokas I, Schlicher L, Lee S, Gyrd-Hansen M, Degterev A, Cuny GD. Design of pyrido[2,3-d]pyrimidin-7-one inhibitors of receptor interacting protein kinase-2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling. European Journal of Medicinal Chemistry. 215: 113252. PMID 33601309 DOI: 10.1016/j.ejmech.2021.113252 |
0.394 |
|
2021 |
Muendlein HI, Connolly WM, Magri Z, Smirnova I, Ilyukha V, Gautam A, Degterev A, Poltorak A. ZBP1 promotes LPS-induced cell death and IL-1β release via RHIM-mediated interactions with RIPK1. Nature Communications. 12: 86. PMID 33397971 DOI: 10.1038/s41467-020-20357-z |
0.326 |
|
2020 |
Lule S, Wu L, Sarro-Schwartz A, Edmiston Iii WJ, Izzy S, Songtachalert T, Ahn SH, Fernandes ND, Jin G, Chung JY, Balachandran S, Lo EH, Kaplan D, Degterev A, Whalen MJ. Cell-specific activation of RIPK1 and MLKL after intracerebral hemorrhage in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20973609. PMID 33210566 DOI: 10.1177/0271678X20973609 |
0.318 |
|
2020 |
Cuny GD, Degterev A. RIPK protein kinase family: Atypical lives of typical kinases. Seminars in Cell & Developmental Biology. PMID 32732131 DOI: 10.1016/J.Semcdb.2020.06.014 |
0.453 |
|
2020 |
Suebsuwong C, Dai B, Pinkas DM, Duddupudi AL, Li L, Bufton JC, Schlicher L, Gyrd-Hansen M, Hu M, Bullock AN, Degterev A, Cuny GD. Receptor-interacting protein kinase 2 (RIPK2) and nucleotide-binding oligomerization domain (NOD) cell signaling inhibitors based on a 3,5-diphenyl-2-aminopyridine scaffold. European Journal of Medicinal Chemistry. 200: 112417. PMID 32505849 DOI: 10.1016/J.Ejmech.2020.112417 |
0.494 |
|
2020 |
Muendlein HI, Sarhan J, Liu BC, Connolly WM, Schworer SA, Smirnova I, Tang AY, Ilyukha V, Pietruska J, Tahmasebi S, Sonenberg N, Degterev A, Poltorak A. Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation. Cell Reports. 30: 699-713.e4. PMID 31968247 DOI: 10.1016/J.Celrep.2019.12.073 |
0.541 |
|
2019 |
Degterev A, Ofengeim D, Yuan J. Targeting RIPK1 for the treatment of human diseases. Proceedings of the National Academy of Sciences of the United States of America. PMID 31048504 DOI: 10.1073/Pnas.1901179116 |
0.408 |
|
2018 |
Saleh D, Degterev A. Chemical Library Screens to Identify Pharmacological Modulators of Necroptosis. Methods in Molecular Biology (Clifton, N.J.). 1857: 19-33. PMID 30136227 DOI: 10.1007/978-1-4939-8754-2_3 |
0.413 |
|
2018 |
Hrdinka M, Schlicher L, Dai B, Pinkas DM, Bufton JC, Picaud S, Ward JA, Rogers C, Suebsuwong C, Nikhar S, Cuny GD, Huber KV, Filippakopoulos P, Bullock AN, Degterev A, et al. Small molecule inhibitors reveal an indispensable scaffolding role of RIPK2 in NOD2 signaling. The Embo Journal. PMID 30026309 DOI: 10.15252/Embj.201899372 |
0.463 |
|
2018 |
Tabtieng T, Degterev A, Gaglia MM. Caspase-dependent suppression of type I interferon signaling promotes KSHV lytic replication. Journal of Virology. PMID 29514903 DOI: 10.1128/Jvi.00078-18 |
0.352 |
|
2018 |
von Mässenhausen A, Tonnus W, Himmerkus N, Parmentier S, Saleh D, Rodriquez D, Ousingsawat J, Ang RL, Weinberg JM, Sanz AB, Ortiz A, Zierleyn A, Becker JU, Baratte B, Desban N, ... ... Degterev A, et al. Phenytoin inhibits necroptosis. Cell Death & Disease. 9: 359. PMID 29500402 DOI: 10.1038/S41419-018-0394-3 |
0.434 |
|
2018 |
Suebsuwong C, Pinkas DM, Ray SS, Bufton JC, Dai B, Bullock AN, Degterev A, Cuny GD. Activation loop targeting strategy for design of receptor-interacting protein kinase 2 (RIPK2) inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 29409752 DOI: 10.1016/J.Bmcl.2018.01.044 |
0.443 |
|
2018 |
Gurol K, Shah S, Degterev A. RIPK1 and RIPK3 - emerging targets in cancer? Molecular and Cellular Therapies. 6. DOI: 10.26781/2052-8426-2018-03 |
0.355 |
|
2017 |
Pattni BS, Jhaveri A, Dutta I, Baleja JD, Degterev A, Torchilin V. Targeting energy metabolism of cancer cells: Combined administration of NCL-240 and 2-DG. International Journal of Pharmaceutics. PMID 28844900 DOI: 10.1016/J.Ijpharm.2017.08.095 |
0.382 |
|
2017 |
Lule S, Wu L, McAllister LM, Edmiston WJ, Chung JY, Levy E, Zheng Y, Gough PJ, Bertin J, Degterev A, Lo EH, Whalen MJ. Genetic Inhibition of Receptor Interacting Protein Kinase-1 Reduces Cell Death and Improves Functional Outcome After Intracerebral Hemorrhage in Mice. Stroke. PMID 28765287 DOI: 10.1161/Strokeaha.117.017702 |
0.456 |
|
2017 |
Quinti L, Dayalan Naidu S, Träger U, Chen X, Kegel-Gleason K, Llères D, Connolly C, Chopra V, Low C, Moniot S, Sapp E, Tousley AR, Vodicka P, Van Kanegan MJ, Kaltenbach LS, ... ... Degterev A, et al. KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington's disease patients. Proceedings of the National Academy of Sciences of the United States of America. PMID 28533375 DOI: 10.1073/Pnas.1614943114 |
0.385 |
|
2017 |
Saleh D, Najjar M, Zelic M, Shah S, Nogusa S, Polykratis A, Paczosa MK, Gough PJ, Bertin J, Whalen M, Fitzgerald KA, Slavov N, Pasparakis M, Balachandran S, Kelliher M, ... ... Degterev A, et al. Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-β Synthesis Induced by Lipopolysaccharide. Journal of Immunology (Baltimore, Md. : 1950). PMID 28461567 DOI: 10.4049/Jimmunol.1601717 |
0.399 |
|
2017 |
Wegner KW, Saleh D, Degterev A. Complex Pathologic Roles of RIPK1 and RIPK3: Moving Beyond Necroptosis. Trends in Pharmacological Sciences. PMID 28126382 DOI: 10.1016/J.Tips.2016.12.005 |
0.511 |
|
2016 |
Najjar M, Saleh D, Zelic M, Nogusa S, Shah S, Tai A, Finger JN, Polykratis A, Gough PJ, Bertin J, Whalen MJ, Pasparakis M, Balachandran S, Kelliher M, Poltorak A, ... Degterev A, et al. RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4. Immunity. PMID 27396959 DOI: 10.1016/J.Immuni.2016.06.007 |
0.523 |
|
2016 |
Degterev A, Linkermann A. Generation of small molecules to interfere with regulated necrosis. Cellular and Molecular Life Sciences : Cmls. PMID 27048812 DOI: 10.1007/S00018-016-2198-X |
0.432 |
|
2016 |
Riehle R, Pattni B, Jhaveri A, Kulkarni A, Thakur G, Degterev A, Torchilin V. Combination Nanopreparations of a Novel Proapoptotic Drug - NCL-240, TRAIL and siRNA. Pharmaceutical Research. PMID 26951567 DOI: 10.1007/S11095-016-1899-Z |
0.327 |
|
2015 |
Sriraman SK, Geraldo V, Luther E, Degterev A, Torchilin V. Cytotoxicity of PEGylated liposomes co-loaded with novel pro-apoptotic drug NCL-240 and the MEK inhibitor cobimetinib against colon carcinoma in vitro. Journal of Controlled Release : Official Journal of the Controlled Release Society. 220: 160-8. PMID 26497930 DOI: 10.1016/J.Jconrel.2015.10.037 |
0.482 |
|
2015 |
Bullock AN, Degterev A. Targeting RIPK1,2,3 to combat inflammation. Oncotarget. 6: 34057-8. PMID 26472031 DOI: 10.18632/Oncotarget.6106 |
0.555 |
|
2015 |
Saleh D, Degterev A. Emerging Roles for RIPK1 and RIPK3 in Pathogen-Induced Cell Death and Host Immunity. Current Topics in Microbiology and Immunology. PMID 26385769 DOI: 10.1007/82_2015_449 |
0.442 |
|
2015 |
Canning P, Ruan Q, Schwerd T, Hrdinka M, Maki JL, Saleh D, Suebsuwong C, Ray S, Brennan PE, Cuny GD, Uhlig HH, Gyrd-Hansen M, Degterev A, Bullock AN. Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors. Chemistry & Biology. 22: 1174-84. PMID 26320862 DOI: 10.1016/J.Chembiol.2015.07.017 |
0.485 |
|
2015 |
Najjar M, Suebsuwong C, Ray SS, Thapa RJ, Maki JL, Nogusa S, Shah S, Saleh D, Gough PJ, Bertin J, Yuan J, Balachandran S, Cuny GD, Degterev A. Structure guided design of potent and selective ponatinib-based hybrid inhibitors for RIPK1. Cell Reports. 10: 1850-60. PMID 25801024 DOI: 10.1016/J.Celrep.2015.02.052 |
0.431 |
|
2015 |
Canning P, Ruan Q, Schwerd T, Hrdinka M, Maki JL, Saleh D, Suebsuwong C, Ray S, Brennan PE, Cuny GD, Uhlig HH, Gyrd-Hansen M, Degterev A, Bullock AN. Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors Chemistry and Biology. DOI: 10.1016/j.chembiol.2015.07.017 |
0.315 |
|
2014 |
Kommagalla Y, Cornea S, Riehle R, Torchilin V, Degterev A, Ramana CV. Optimization of the anti-cancer activity of phosphatidylinositol-3 kinase pathway inhibitor PITENIN-1: switching a thiourea with 1,2,3-triazole. Medchemcomm. 5: 1359-1363. PMID 25505943 DOI: 10.1039/C4Md00109E |
0.392 |
|
2014 |
Degterev A, Zhou W, Maki JL, Yuan J. Assays for necroptosis and activity of RIP kinases. Methods in Enzymology. 545: 1-33. PMID 25065884 DOI: 10.1016/B978-0-12-801430-1.00001-9 |
0.46 |
|
2014 |
Zhu X, Park J, Golinski J, Qiu J, Khuman J, Lee CC, Lo EH, Degterev A, Whalen MJ. Role of Akt and mammalian target of rapamycin in functional outcome after concussive brain injury in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 34: 1531-9. PMID 24938400 DOI: 10.1038/Jcbfm.2014.113 |
0.396 |
|
2014 |
Dvoriantchikova G, Degterev A, Ivanov D. Retinal ganglion cell (RGC) programmed necrosis contributes to ischemia-reperfusion-induced retinal damage. Experimental Eye Research. 123: 1-7. PMID 24751757 DOI: 10.1016/J.Exer.2014.04.009 |
0.326 |
|
2014 |
Schworer SA, Smirnova II, Kurbatova I, Bagina U, Churova M, Fowler T, Roy AL, Degterev A, Poltorak A. Toll-like receptor-mediated down-regulation of the deubiquitinase cylindromatosis (CYLD) protects macrophages from necroptosis in wild-derived mice. The Journal of Biological Chemistry. 289: 14422-33. PMID 24706750 DOI: 10.1074/Jbc.M114.547547 |
0.416 |
|
2014 |
Liu Q, Qiu J, Liang M, Golinski J, van Leyen K, Jung JE, You Z, Lo EH, Degterev A, Whalen MJ. Akt and mTOR mediate programmed necrosis in neurons. Cell Death & Disease. 5: e1084. PMID 24577082 DOI: 10.1038/Cddis.2014.69 |
0.54 |
|
2014 |
Newton K, Hildebrand JM, Shen Z, Rodriguez D, Alvarez-Diaz S, Petersen S, Shah S, Dugger DL, Huang C, Auwerx J, Vandenabeele P, Green DR, Ashkenazi A, Dixit VM, Kaiser WJ, ... ... Degterev A, et al. Is SIRT2 required for necroptosis? Nature. 506: E4-6. PMID 24572428 DOI: 10.1038/Nature13024 |
0.401 |
|
2013 |
Thapa RJ, Nogusa S, Chen P, Maki JL, Lerro A, Andrake M, Rall GF, Degterev A, Balachandran S. Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases. Proceedings of the National Academy of Sciences of the United States of America. 110: E3109-18. PMID 23898178 DOI: 10.1073/Pnas.1301218110 |
0.484 |
|
2013 |
Riehle RD, Cornea S, Degterev A. Role of phosphatidylinositol 3,4,5-trisphosphate in cell signaling. Advances in Experimental Medicine and Biology. 991: 105-39. PMID 23775693 DOI: 10.1007/978-94-007-6331-9_7 |
0.434 |
|
2013 |
Maki JL, Degterev A. Activity assays for receptor-interacting protein kinase 1:a key regulator of necroptosis. Methods in Molecular Biology (Clifton, N.J.). 1004: 31-42. PMID 23733567 DOI: 10.1007/978-1-62703-383-1_3 |
0.513 |
|
2013 |
Maki JL, Tres Brazell J, Teng X, Cuny GD, Degterev A. Expression and purification of active receptor interacting protein 1 kinase using a baculovirus system. Protein Expression and Purification. 89: 156-61. PMID 23523699 DOI: 10.1016/J.Pep.2013.03.002 |
0.468 |
|
2013 |
Xie T, Peng W, Liu Y, Yan C, Maki J, Degterev A, Yuan J, Shi Y. Structural basis of RIP1 inhibition by necrostatins. Structure (London, England : 1993). 21: 493-9. PMID 23473668 DOI: 10.1016/J.Str.2013.01.016 |
0.476 |
|
2013 |
McNamara CR, Ahuja R, Osafo-Addo AD, Barrows D, Kettenbach A, Skidan I, Teng X, Cuny GD, Gerber S, Degterev A. Akt Regulates TNFα synthesis downstream of RIP1 kinase activation during necroptosis. Plos One. 8: e56576. PMID 23469174 DOI: 10.1371/Journal.Pone.0056576 |
0.721 |
|
2013 |
Degterev A, Maki JL, Yuan J. Activity and specificity of necrostatin-1, small-molecule inhibitor of RIP1 kinase. Cell Death and Differentiation. 20: 366. PMID 23197295 DOI: 10.1038/Cdd.2012.133 |
0.491 |
|
2012 |
Takahashi N, Duprez L, Grootjans S, Cauwels A, Nerinckx W, Duhadaway JB, Goossens V, Roelandt R, Van Hauwermeiren F, Libert C, Declercq W, Callewaert N, Prendergast GC, Degterev A, Yuan J, et al. Necrostatin-1 analogues: Critical issues on the specificity, activity and in vivo use in experimental disease models Cell Death and Disease. 3. PMID 23190609 DOI: 10.1038/Cddis.2012.176 |
0.414 |
|
2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Degterev A, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.318 |
|
2012 |
Choi S, Keys H, Staples RJ, Yuan J, Degterev A, Cuny GD. Optimization of tricyclic Nec-3 necroptosis inhibitors for in vitro liver microsomal stability. Bioorganic & Medicinal Chemistry Letters. 22: 5685-8. PMID 22832318 DOI: 10.1016/J.Bmcl.2012.06.098 |
0.378 |
|
2012 |
Maki JL, Smith EE, Teng X, Ray SS, Cuny GD, Degterev A. Fluorescence polarization assay for inhibitors of the kinase domain of receptor interacting protein 1. Analytical Biochemistry. 427: 164-74. PMID 22658960 DOI: 10.1016/J.Ab.2012.05.019 |
0.454 |
|
2012 |
Ofengeim D, Shi P, Miao B, Fan J, Xia X, Fan Y, Lipinski MM, Hashimoto T, Polydoro M, Yuan J, Wong ST, Degterev A. Identification of small molecule inhibitors of neurite loss induced by Aβ peptide using high content screening. The Journal of Biological Chemistry. 287: 8714-23. PMID 22277654 DOI: 10.1074/Jbc.M111.290957 |
0.362 |
|
2012 |
Miao B, Skidan I, Yang J, You Z, Fu X, Famulok M, Schaffhausen B, Torchilin V, Yuan J, Degterev A. Inhibition of cell migration by PITENINs: The role of ARF6 Oncogene. 31: 4317-4332. PMID 22179837 DOI: 10.1038/Onc.2011.593 |
0.415 |
|
2012 |
Park J, Zhang J, Qiu J, Zhu X, Degterev A, Lo EH, Whalen MJ. Combination therapy targeting Akt and mammalian target of rapamycin improves functional outcome after controlled cortical impact in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 32: 330-40. PMID 21934697 DOI: 10.1038/Jcbfm.2011.131 |
0.356 |
|
2012 |
Maki JL, Teng X, Smith EE, Ray S, Yuan J, Cuny GD, Degterev A. Abstract SY27-03: Development of necrostatins, small molecule inhibitors of RIP1-kinase signaling and necroptosis Cancer Research. 72. DOI: 10.1158/1538-7445.Am2012-Sy27-03 |
0.587 |
|
2011 |
Badr CE, Wurdinger T, Nilsson J, Niers JM, Whalen M, Degterev A, Tannous BA. Lanatoside C sensitizes glioblastoma cells to tumor necrosis factor-related apoptosis-inducing ligand and induces an alternative cell death pathway. Neuro-Oncology. 13: 1213-24. PMID 21757445 DOI: 10.1093/Neuonc/Nor067 |
0.434 |
|
2011 |
McNamara CR, Degterev A. Small-molecule inhibitors of the PI3K signaling network. Future Medicinal Chemistry. 3: 549-65. PMID 21526896 DOI: 10.4155/Fmc.11.12 |
0.707 |
|
2011 |
Miao B, Degterev A. Targeting phospshatidylinositol 3-kinase signaling with novel phosphatidylinositol 3,4,5-triphosphate antagonists. Autophagy. 7: 650-1. PMID 21460619 DOI: 10.4161/Auto.7.6.15248 |
0.465 |
|
2010 |
Miao B, Skidan I, Yang J, Lugovskoy A, Reibarkh M, Long K, Brazell T, Durugkar KA, Maki J, Ramana CV, Schaffhausen B, Wagner G, Torchilin V, Yuan J, Degterev A. Small molecule inhibition of phosphatidylinositol-3,4,5-triphosphate (PIP3) binding to pleckstrin homology domains. Proceedings of the National Academy of Sciences of the United States of America. 107: 20126-31. PMID 21041639 DOI: 10.1073/Pnas.1004522107 |
0.455 |
|
2010 |
Rosenbaum DM, Degterev A, David J, Rosenbaum PS, Roth S, Grotta JC, Cuny GD, Yuan J, Savitz SI. Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia-reperfusion injury model. Journal of Neuroscience Research. 88: 1569-76. PMID 20025059 DOI: 10.1002/Jnr.22314 |
0.35 |
|
2010 |
Ramana CV, Patel P, Vanka K, Miao B, Degterev A. A combined experimental and density functional theory study on the Pd-mediated cycloisomerization of o-alkynylnitrobenzenes - Synthesis of isatogens and their evaluation as modulators of ROS-mediated cell death European Journal of Organic Chemistry. 5955-5966. DOI: 10.1002/Ejoc.201000769 |
0.336 |
|
2009 |
Miao B, Degterev A. Methods to analyze cellular necroptosis. Methods in Molecular Biology (Clifton, N.J.). 559: 79-93. PMID 19609750 DOI: 10.1007/978-1-60327-017-5_6 |
0.494 |
|
2008 |
Hitomi J, Christofferson DE, Ng A, Yao J, Degterev A, Xavier RJ, Yuan J. Identification of a molecular signaling network that regulates a cellular necrotic cell death pathway. Cell. 135: 1311-23. PMID 19109899 DOI: 10.1016/J.Cell.2008.10.044 |
0.49 |
|
2008 |
Ch'en IL, Beisner DR, Degterev A, Lynch C, Yuan J, Hoffmann A, Hedrick SM. Antigen-mediated T cell expansion regulated by parallel pathways of death. Proceedings of the National Academy of Sciences of the United States of America. 105: 17463-8. PMID 18981423 DOI: 10.1073/Pnas.0808043105 |
0.441 |
|
2008 |
Zheng W, Degterev A, Hsu E, Yuan J, Yuan C. Structure-activity relationship study of a novel necroptosis inhibitor, necrostatin-7. Bioorganic & Medicinal Chemistry Letters. 18: 4932-5. PMID 18768316 DOI: 10.1016/j.bmcl.2008.08.058 |
0.323 |
|
2008 |
You Z, Savitz SI, Yang J, Degterev A, Yuan J, Cuny GD, Moskowitz MA, Whalen MJ. Necrostatin-1 reduces histopathology and improves functional outcome after controlled cortical impact in mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 1564-73. PMID 18493258 DOI: 10.1038/Jcbfm.2008.44 |
0.326 |
|
2008 |
Teng X, Keys H, Yuan J, Degterev A, Cuny GD. Structure-activity relationship and liver microsome stability studies of pyrrole necroptosis inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 3219-23. PMID 18467094 DOI: 10.1016/J.Bmcl.2008.04.048 |
0.407 |
|
2008 |
Degterev A, Yuan J. Expansion and evolution of cell death programmes. Nature Reviews. Molecular Cell Biology. 9: 378-90. PMID 18414491 DOI: 10.1038/Nrm2393 |
0.426 |
|
2008 |
Degterev A, Hitomi J, Germscheid M, Ch'en IL, Korkina O, Teng X, Abbott D, Cuny GD, Yuan C, Wagner G, Hedrick SM, Gerber SA, Lugovskoy A, Yuan J. Identification of RIP1 kinase as a specific cellular target of necrostatins. Nature Chemical Biology. 4: 313-21. PMID 18408713 DOI: 10.1038/Nchembio.83 |
0.548 |
|
2008 |
Ch'en IL, Beisner DR, Degterev A, Lynch C, Yuan J, Hoffmann A, Hedrick SM. Caspase‐8 regulates a form of death that is distinct from apoptosis in T cells The Faseb Journal. 22: 369-369. DOI: 10.1096/Fasebj.22.2_Supplement.369 |
0.389 |
|
2007 |
Yi CH, Sogah DK, Boyce M, Degterev A, Christofferson DE, Yuan J. A genome-wide RNAi screen reveals multiple regulators of caspase activation. The Journal of Cell Biology. 179: 619-26. PMID 17998402 DOI: 10.1083/Jcb.200708090 |
0.471 |
|
2007 |
Teng X, Keys H, Jeevanandam A, Porco JA, Degterev A, Yuan J, Cuny GD. Structure-activity relationship study of [1,2,3]thiadiazole necroptosis inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 6836-40. PMID 17964153 DOI: 10.1016/J.Bmcl.2007.10.024 |
0.45 |
|
2007 |
Jagtap PG, Degterev A, Choi S, Keys H, Yuan J, Cuny GD. Structure-activity relationship study of tricyclic necroptosis inhibitors. Journal of Medicinal Chemistry. 50: 1886-95. PMID 17361994 DOI: 10.1021/Jm061016O |
0.365 |
|
2007 |
Wang K, Li J, Degterev A, Hsu E, Yuan J, Yuan C. Structure-activity relationship analysis of a novel necroptosis inhibitor, Necrostatin-5. Bioorganic & Medicinal Chemistry Letters. 17: 1455-65. PMID 17270434 DOI: 10.1016/J.Bmcl.2006.11.056 |
0.415 |
|
2007 |
Moerke NJ, Aktas H, Chen H, Cantel S, Reibarkh MY, Fahmy A, Gross JD, Degterev A, Yuan J, Chorev M, Halperin JA, Wagner G. Small-molecule inhibition of the interaction between the translation initiation factors eIF4E and eIF4G. Cell. 128: 257-67. PMID 17254965 DOI: 10.1016/J.Cell.2006.11.046 |
0.393 |
|
2007 |
Yuan J, Degterev A, Huang Z, Jagtap P, Cuny G, Moskowitz M. Studying mechanisms of cell death: from apoptosis to necrosis The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A38-D |
0.403 |
|
2005 |
Degterev A, Huang Z, Boyce M, Li Y, Jagtap P, Mizushima N, Cuny GD, Mitchison TJ, Moskowitz MA, Yuan J. Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nature Chemical Biology. 1: 112-9. PMID 16408008 DOI: 10.1038/Nchembio711 |
0.502 |
|
2005 |
Teng X, Degterev A, Jagtap P, Xing X, Choi S, Denu R, Yuan J, Cuny GD. Structure-activity relationship study of novel necroptosis inhibitors. Bioorganic & Medicinal Chemistry Letters. 15: 5039-44. PMID 16153840 DOI: 10.1016/J.Bmcl.2005.07.077 |
0.411 |
|
2004 |
Boyce M, Degterev A, Yuan J. Caspases: An ancient cellular sword of Damocles Cell Death and Differentiation. 11: 29-37. PMID 14647235 DOI: 10.1038/Sj.Cdd.4401339 |
0.359 |
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2003 |
Degterev A, Boyce M, Yuan J. A decade of caspases. Oncogene. 22: 8543-67. PMID 14634618 DOI: 10.1038/Sj.Onc.1207107 |
0.42 |
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2003 |
Yuan J, Lipinski M, Degterev A. Diversity in the mechanisms of neuronal cell death Neuron. 40: 401-413. PMID 14556717 DOI: 10.1016/S0896-6273(03)00601-9 |
0.405 |
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2001 |
Degterev A, Boyce M, Yuan J. The channel of death Journal of Cell Biology. 155: 695-697. PMID 11724809 DOI: 10.1083/Jcb.200110147 |
0.305 |
|
2001 |
Degterev A, Lugovskoy A, Cardone M, Mulley B, Wagner G, Mitchison T, Yuan J. Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL Nature Cell Biology. 3: 173-182. PMID 11175750 DOI: 10.1038/35055085 |
0.401 |
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Low-probability matches (unlikely to be authored by this person) |
2013 |
Riehle RD, Cornea S, Degterev A, Torchilin V. Micellar formulations of pro-apoptotic DM-PIT-1 analogs and TRAIL in vitro and in vivo. Drug Delivery. 20: 78-85. PMID 23495715 DOI: 10.3109/10717544.2013.766780 |
0.299 |
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1999 |
Degterev A, Foster JA. The role of NF-1 factors in regulation of elastin gene transcription. Matrix Biology : Journal of the International Society For Matrix Biology. 18: 295-307. PMID 10429948 DOI: 10.1016/S0945-053X(99)00020-7 |
0.299 |
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2006 |
Shibata M, Lu T, Furuya T, Degterev A, Mizushima N, Yoshimori T, MacDonald M, Yankner B, Yuan J. Regulation of intracellular accumulation of mutant Huntingtin by Beclin 1. The Journal of Biological Chemistry. 281: 14474-85. PMID 16522639 DOI: 10.1074/Jbc.M600364200 |
0.299 |
|
2016 |
Pattni BS, Nagelli SG, Aryasomayajula B, Deshpande PP, Kulkarni A, Hartner WC, Thakur G, Degterev A, Torchilin VP. Erratum to: Targeting of Micelles and Liposomes Loaded with the Pro-Apoptotic Drug, NCL-240, into NCI/ADR-RES Cells in a 3D Spheroid Model. Pharmaceutical Research. PMID 27599990 DOI: 10.1007/S11095-016-2034-X |
0.296 |
|
1999 |
Degterev A, Yuan J. A new savior for neurons Nature Neuroscience. 2: 930-932. PMID 10526325 DOI: 10.1038/14712 |
0.288 |
|
2021 |
Wu L, Chung JY, Cao T, Jin G, Edmiston WJ, Hickman S, Levy ES, Whalen JA, Abrams ESL, Degterev A, Lo EH, Tozzi L, Kaplan DL, El Khoury J, Whalen MJ. Genetic inhibition of RIPK3 ameliorates functional outcome in controlled cortical impact independent of necroptosis. Cell Death & Disease. 12: 1064. PMID 34753914 DOI: 10.1038/s41419-021-04333-z |
0.28 |
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2008 |
Cuny GD, Degterev A, Yuan J. Necroptosis - A novel cell death mechanism Drugs of the Future. 33: 225-233. DOI: 10.1358/dof.2008.033.03.1173882 |
0.28 |
|
2009 |
Skidan I, Miao B, Thekkedath RV, Dholakia P, Degterev A, Torchilin V. In vitro cytotoxicity of novel pro-apoptotic agent DM-PIT-1 in PEG-PE-based micelles alone and in combination with TRAIL. Drug Delivery. 16: 45-51. PMID 19555308 DOI: 10.1080/10717540802517951 |
0.278 |
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2002 |
Lugovskoy AA, Degterev AI, Fahmy AF, Zhou P, Gross JD, Yuan J, Wagner G. A novel approach for characterizing protein ligand complexes: molecular basis for specificity of small-molecule Bcl-2 inhibitors. Journal of the American Chemical Society. 124: 1234-40. PMID 11841292 DOI: 10.1021/Ja011239Y |
0.249 |
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2022 |
Maslov LN, Popov SV, Naryzhnaya NV, Mukhomedzyanov AV, Kurbatov BK, Derkachev IA, Boshchenko AA, Khaliulin I, Prasad NR, Singh N, Degterev A, Tomilova EA, Sapozhenkova EV. The regulation of necroptosis and perspectives for the development of new drugs preventing ischemic/reperfusion of cardiac injury. Apoptosis : An International Journal On Programmed Cell Death. PMID 35986803 DOI: 10.1007/s10495-022-01760-x |
0.247 |
|
2007 |
Zhang Y, Zhou X, Degterev A, Lipinski M, Adjeroh D, Yuan J, Wong ST. A novel tracing algorithm for high throughput imaging Screening of neuron-based assays. Journal of Neuroscience Methods. 160: 149-62. PMID 16987551 DOI: 10.1016/J.Jneumeth.2006.07.028 |
0.239 |
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2011 |
Skidan I, Grunwald J, Thekkedath R, Degterev A, Torchilin V. A HPLC method for the quantitative determination of N-(2-hydroxy-5-nitrophenylcarbamothioyl)-3,5-dimethylbenzamide in biological samples. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 879: 1610-6. PMID 21514904 DOI: 10.1016/J.Jchromb.2011.03.055 |
0.233 |
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2010 |
Huang Y, Zhou X, Miao B, Lipinski M, Zhang Y, Li F, Degterev A, Yuan J, Hu G, Wong ST. A computational framework for studying neuron morphology from in vitro high content neuron-based screening. Journal of Neuroscience Methods. 190: 299-309. PMID 20580743 DOI: 10.1016/J.Jneumeth.2010.05.012 |
0.228 |
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2007 |
Zhang Y, Zhou X, Degterev A, Lipinski M, Adjeroh D, Yuan J, Wong ST. Automated neurite extraction using dynamic programming for high-throughput screening of neuron-based assays. Neuroimage. 35: 1502-15. PMID 17363284 DOI: 10.1016/J.Neuroimage.2007.01.014 |
0.226 |
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2005 |
Degterev A, Huang Z, Boyce M, Li Y, Jagtap P, Mizushima N, Cuny GD, Mitchison TJ, Moskowitz MA, Yuan J. Corrigendum: Chemical Inhibitor of Nonapoptotic Cell Death With Therapeutic Potential for Ischemic Brain Injury Nature Chemical Biology. 1: 234. DOI: 10.1038/nchembio0905-234a |
0.224 |
|
2018 |
von Mässenhausen A, Tonnus W, Himmerkus N, Parmentier S, Saleh D, Rodriguez D, Ousingsawat J, Ang RL, Weinberg JM, Sanz AB, Ortiz A, Zierleyn A, Becker JU, Baratte B, Desban N, ... ... Degterev A, et al. Correction to: Phenytoin inhibits necroptosis. Cell Death & Disease. 9: 622. PMID 29795371 DOI: 10.1038/S41419-018-0638-2 |
0.22 |
|
2006 |
Xiong G, Zhou X, Degterev A, Ji L, Wong ST. Automated neurite labeling and analysis in fluorescence microscopy images. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 69: 494-505. PMID 16680708 DOI: 10.1002/Cyto.A.20296 |
0.219 |
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2022 |
Muendlein HI, Connolly WM, Magri Z, Jetton D, Smirnova I, Degterev A, Balachandran S, Poltorak A. ZBP1 promotes inflammatory responses downstream of TLR3/TLR4 via timely delivery of RIPK1 to TRIF. Proceedings of the National Academy of Sciences of the United States of America. 119: e2113872119. PMID 35666872 DOI: 10.1073/pnas.2113872119 |
0.185 |
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2016 |
Pattni BS, Nagelli SG, Aryasomayajula B, Deshpande PP, Kulkarni A, Hartner WC, Thakur G, Degterev A, Torchilin VP. Targeting of Micelles and Liposomes Loaded with the Pro-Apoptotic Drug, NCL-240, into NCI/ADR-RES Cells in a 3D Spheroid Model. Pharmaceutical Research. PMID 27351426 DOI: 10.1007/s11095-016-1978-1 |
0.164 |
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2009 |
Sánchez-Olea R, Calera MR, Degterev A. Molecular pathways involved in cell death after chemically induced DNA damage. Exs. 99: 209-30. PMID 19157063 DOI: 10.1007/978-3-7643-8336-7_8 |
0.161 |
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2021 |
Siokas I, Zhang D, Poltorak A, Muendlein H, Degterev A. Immunoprecipitation Strategies to Isolate RIPK1/RIPK3 Complexes in Mouse Macrophages. Current Protocols. 1: e156. PMID 34106523 DOI: 10.1002/cpz1.156 |
0.16 |
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2009 |
Huang Y, Zhou X, Miao B, Lipinski M, Xia Z, Hu G, Degterev A, Yuan J, Wong ST. An Image Based System Biology Approach for Alzheimer's Disease Pathway Analysis. Ieee/Nih Life Science Systems and Applications Workshop. Ieee/Nih Life Science Systems and Applications Workshop. 2009: 128-132. PMID 20585413 DOI: 10.1109/LISSA.2009.4906726 |
0.138 |
|
1990 |
Verovskii VN, Degterev AI, Sukhova NM, Buzukov AA, Leonova EY, Tatarskaya NK. Structure, toxtcity, and antitumor activity of nitro-heterocyclic compounds, their metabolic activation in liver and tumor microsomes Pharmaceutical Chemistry Journal. 24: 615-620. DOI: 10.1007/BF00767023 |
0.116 |
|
2016 |
Riehle R, Pattni B, Jhaveri A, Kulkarni A, Thakur G, Degterev A, Torchilin V. Combination Nanopreparations of a Novel Proapoptotic Drug – NCL-240, TRAIL and siRNA Pharmaceutical Research. 1-15. DOI: 10.1007/s11095-016-1899-z |
0.112 |
|
1997 |
Degterev AK. Influence of horizontal turbulence on vertical oxygen transport in the sea Russian Meteorology and Hydrology. 69-72. |
0.053 |
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2012 |
Rybin AV, Degterev AV, Kravchunovskaya EA, Chibisova MV, Neroda AS, Melekestsev IV, Razzhigaeva NG, Chashchin SA, Chirkov SA, Koroteev IG, Arslanov KA. A weak phreatic eruption of June 2010 on Ekarma Volcano, Kuril Islands as a possible precursor of a future large magmatic eruption Journal of Volcanology and Seismology. 6: 290-300. DOI: 10.1134/S0742046312050041 |
0.048 |
|
1993 |
Eremeeva LV, Degterev AK. On the problem of a turbid layer occurring near the upper boundary of the hydrogen sulphide zone in the Black Sea Physical Oceanography. 4: 169-172. DOI: 10.1007/BF02199135 |
0.048 |
|
1981 |
Klyuyev VV, VAasil'yev VM, Degterev AP, Yesilevskiy VP. ON THE STATISTICAL THEORY OF THE RELATION BETWEEN THE PARAMETERS OF BARKHAUSEN EFFECT AND HYSTERESIS LOOP Physics of Metals and Metallography. 52: 60-64. |
0.046 |
|
2001 |
Degterev AK. Earthquake effect on hydrogen sulfide contamination of the Black Sea Russian Meteorology and Hydrology. 38-42. |
0.045 |
|
2016 |
Degterev A, Burtsev M. Simulation of learning in neuronal culture Advances in Intelligent Systems and Computing. 449: 47-52. DOI: 10.1007/978-3-319-32554-5_7 |
0.045 |
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2012 |
Degterev AV, Rybin AV, Melekestsev IV, Razzhigaeva NG. Explosive eruptions of the Sarychev Peak volcano in the Holocene on Matua Island, the Central Kuriles: The tephra geochemistry Russian Journal of Pacific Geology. 6: 423-432. DOI: 10.1134/S1819714012060024 |
0.044 |
|
1986 |
Vasil'ev VM, Degterev AP, Koshelev AA, Andrianov AV. SOME COMPUTATION AND DESIGN PROBLEMS OF INDUCTION TRANSDUCERS FOR THE DETECTION OF BARKHAUSEN JUMPS The Soviet Journal of Nondestructive Testing. 22: 128-137. |
0.044 |
|
2015 |
Martynov YA, Rybin AV, Degterev AV, Ostapenko DS, Martynov AY. Geochemical evolution of volcanism of Matua Island in the Central Kurils Indian Journal of Thoracic and Cardiovascular Surgery. 31: 11-21. DOI: 10.1134/S1819714015010042 |
0.044 |
|
2007 |
Degterev AK. Modeling of volume reverberation in the ray approximation Physical Oceanography. 17: 296-302. DOI: 10.1007/s11110-007-0023-7 |
0.043 |
|
1992 |
Ryabinin AI, Eremeeva LV, Degterev AK. Some regularities of the ozone distribution in the near-water atmospheric layer Soviet Journal of Physical Oceanography. 3: 405-407. DOI: 10.1007/BF02198072 |
0.041 |
|
1984 |
Lomaev GV, Malyshev VS, Degterev AP. REVIEW OF THE APPLICATION OF THE BARKHAUSEN EFFECT IN NONDESTRUCTIVE INSPECTION The Soviet Journal of Nondestructive Testing. 20: 189-203. |
0.041 |
|
2010 |
Levin BV, Razzhigaeva NG, Ganzei KS, Rybin AV, Degterev AV. Change of landscape structure of Matua Island after the Sarichev Volcano Peak Eruption June 12-15, 2009 Doklady Earth Sciences. 431: 514-517. DOI: 10.1134/S1028334X10040215 |
0.041 |
|
1981 |
Klyuev VV, Vasil'ev VM, Degterev AP, Esilevskii VP, Popov AV. CONTROL OF PHASE TRANSFORMATIONS IN FERROMAGNETIC MATERIALS WITH THE AID OF THE BARKHAUSEN EFFECT AND PARAMETERS OF THE HYSTERESIS LOOP The Soviet Journal of Nondestructive Testing. 17: 948-951. |
0.036 |
|
1991 |
Degterev AK, Ryabinin AI. Modeling the large-scale anomalies of dissolved gas distribution in the upper ocean layer Meteorologiya I Gidrologiya. 80-84. |
0.034 |
|
2000 |
Degterev AK. Assessment of temperature rise in an active layer of the Black sea for 1985-1997 Russian Meteorology and Hydrology. 55-59. |
0.029 |
|
1978 |
Klyuev VV, Degterev AN, Ketkovich AA, Klochko VA, Konzhukov FI, Lange YV, Tverdokhlebov VN, Fedosenko YK. Nondestructive testing means and methods at the "TestÉkspo-77" exhibition Measurement Techniques. 21: 1461-1466. DOI: 10.1007/BF00823097 |
0.029 |
|
1987 |
Degterev AK. ONE-DIMENSIONAL MODEL OF GAS EXCHANGE BETWEEN THE OCEAN AND ATMOSPHERE Soviet Meteorology and Hydrology. 99-102. |
0.028 |
|
1994 |
Degterev AK, Kolobaev PA. The dependence of the bubble size distribution on hydrometeorological parameters in the upper levels of the sea Izvestiya - Atmospheric &Amp; Oceanic Physics. 29: 664-667. |
0.025 |
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1983 |
Filippov EM, Degterev AK, Ryabinin AI. MEASURING SEA WATER SALINITY FROM THE ATTENUATION OF AMERICIUM 241 GAMMA RAYS Soviet Meteorology and Hydrology. 53-57. |
0.024 |
|
1986 |
Eremeev VN, Degterev AK. CO//2 EXCHANGE BETWEEN THE OCEAN AND ATMOSPHERE IN THE SOUTH ATLANTIC Soviet Meteorology and Hydrology. 51-54. |
0.023 |
|
2008 |
Degterev AK, Degtereva LN. Estimation of changes in energy consumption for heat supply due to interannual temperature variability in the south of the Ukraine Russian Meteorology and Hydrology. 33: 715-717. DOI: 10.3103/S1068373908110058 |
0.021 |
|
1986 |
Vasil'yev VM, Degterev AP, Andrianov AV. COMPARATIVE ANALYSIS OF NORMAL AND TANGENTIAL FIELDS OF MAGNETIZATION DISCONTINUITIES Physics of Metals and Metallography. 61: 1-10. |
0.021 |
|
1992 |
Eremeeva LV, Degterev AK. Variability of the oxygen deficit near the H2S zone in the Black Sea Soviet Journal of Physical Oceanography. 3: 159-162. DOI: 10.1007/BF02197623 |
0.02 |
|
1995 |
Degterev AK, Demyshev SG. A model of hydrogen sulfide zone boundary in the Black Sea Russian Meteorology and Hydrology. 12: 49-53. |
0.02 |
|
2011 |
Degterev AK. Estimation of the rate of water renewal in the ocean conveyor Russian Meteorology and Hydrology. 36: 403-408. DOI: 10.3103/S1068373911060070 |
0.02 |
|
1992 |
Degterev AK, Smirnov EV. An increase in the partial pressure of CO2 in the Tropical Atlantic Meteorologiya I Gidrologiya. 98-99. |
0.016 |
|
1994 |
Degterev AK, Pyrkh VV. Comparative assessment of factors affecting the boundary of hydrogen sulfide in the Black Sea Russian Meteorology &Amp; Hydrology. 9: 45-48. |
0.016 |
|
1991 |
Bezzabotnov VS, Degterev AK, Eremeev VN. Determination of the gas exchange rate in whitecaps using measurements of the bubble concentration Soviet Journal of Physical Oceanography. 2: 221-225. DOI: 10.1007/BF02197210 |
0.016 |
|
1992 |
Degterev AK, Smirnov EV. The increase in CO2 partial pressure in the tropical Atlantic Soviet Meteorology &Amp; Hydrology. 10: 83-85. |
0.016 |
|
1993 |
Eremeeva LV, Degterev AK. Estimation of the upwelling rate of deep waters in the Black Sea from the H2S vertical distribution Physical Oceanography. 4: 85-87. DOI: 10.1007/BF02197102 |
0.014 |
|
1994 |
Arzamastsev AP, Grigor'ev NB, Ordabaeva SK, Ryzhenkova AP, Degterev AV, Arystanova TP. Polarographic determination of vitamin U in formaldehyde solutions Pharmaceutical Chemistry Journal. 28: 356-359. DOI: 10.1007/BF02218434 |
0.012 |
|
2007 |
Degterev AK. Estimation of the influence of surface waves on the sea surface radiative balance Russian Meteorology and Hydrology. 32: 461-464. DOI: 10.3103/S1068373907070072 |
0.011 |
|
2001 |
Degterev AK. The effect of earthquake on hydrogen sulfide contamination of the Black Sea Meteorologiya I Gidrologiya. 59-65. |
0.01 |
|
2011 |
Degterev AV. Pyroclastic deposits from Sarychev Peak, Matua Island discharged in June 2009 Journal of Volcanology and Seismology. 5: 278-285. DOI: 10.1134/S0742046311040026 |
0.01 |
|
2002 |
Degterev AK, Degtereva LN. Estimation of the impact of seasonal temperature changes upon energy consumption in Ukraine during the heating period Meteorologiya I Gidrologiya. 58-62. |
0.01 |
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1985 |
Filippov EM, Degterev AK, Baksheeva IP, Lamanova IA, Ryabinin AI, Saltykova LV. Characteristic spectra of seawater exposed to low-energy γ radiation Journal of Applied Spectroscopy. 42: 178-182. DOI: 10.1007/BF00657199 |
0.01 |
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1982 |
Degterev AK, Filippov EM. X-ray fluorescence analysis of seawater Journal of Applied Spectroscopy. 37: 922-926. DOI: 10.1007/BF00663167 |
0.01 |
|
1982 |
Dreizin VE, Degterev AP. PROBLEM OF MULTIPARAMETRIC ELECTROMAGNETIC STRUCTURESCOPY IN TERMS OF SYSTEM APPROACH . 7: 451-459. |
0.01 |
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Hide low-probability matches. |