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Guofeng You - Publications

Affiliations: 
Graduate School - New Brunswick Rutgers University, New Brunswick, New Brunswick, NJ, United States 
Area:
Pharmacy, Biochemistry
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72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Yu Z, Wang H, You G. The regulation of human organic anion transporter 4 by insulin-like growth factor 1 and protein kinase B signaling. Biochemical Pharmacology. 215: 115702. PMID 37487877 DOI: 10.1016/j.bcp.2023.115702  0.414
2023 Liang Z, You G. Chloroquine and Hydroxychloroquine, as Proteasome Inhibitors, Upregulate the Expression and Activity of Organic Anion Transporter 3. Pharmaceutics. 15. PMID 37376173 DOI: 10.3390/pharmaceutics15061725  0.619
2023 Yu Z, Zhang J, Liang Z, Wu J, Liu K, You G. Pancreatic Hormone Insulin Modulates Organic Anion Transporter 1 in the Kidney: Regulation via Remote Sensing and Signaling Network. The Aaps Journal. 25: 13. PMID 36627500 DOI: 10.1208/s12248-022-00778-y  0.343
2022 Fan Y, Wang H, Yu Z, Liang Z, Li Y, You G. Inhibition of proteasome, but not lysosome, upregulates organic anion transporter 3 in vitro and in vivo. Biochemical Pharmacology. 208: 115387. PMID 36549459 DOI: 10.1016/j.bcp.2022.115387  0.56
2021 Yu Z, Liu C, Zhang J, Liang Z, You G. Protein kinase C regulates organic anion transporter 1 through phosphorylating ubiquitin ligase Nedd4-2. Bmc Molecular and Cell Biology. 22: 53. PMID 34663225 DOI: 10.1186/s12860-021-00393-3  0.575
2021 Fan Y, Liang Z, Zhang J, You G. Oral Proteasomal Inhibitors Ixazomib, Oprozomib, and Delanzomib Upregulate the Function of Organic Anion Transporter 3 (OAT3): Implications in OAT3-Mediated Drug-Drug Interactions. Pharmaceutics. 13. PMID 33670955 DOI: 10.3390/pharmaceutics13030314  0.504
2020 Zhang J, Liu C, You G. Ubiquitin-specific peptidase 8 regulates the trafficking and stability of the human organic anion transporter 1. Biochimica Et Biophysica Acta. General Subjects. 129701. PMID 32818533 DOI: 10.1016/J.Bbagen.2020.129701  0.658
2020 Zhang J, Wang H, Fan Y, Yu Z, You G. Regulation of organic anion transporters: Role in physiology, pathophysiology, and drug elimination. Pharmacology & Therapeutics. 107647. PMID 32758646 DOI: 10.1016/J.Pharmthera.2020.107647  0.586
2020 Fan Y, You G. Proteasome Inhibitors Bortezomib and Carfilzomib Stimulate the Transport Activity of Human Organic Anion Transporter 1. Molecular Pharmacology. PMID 32234809 DOI: 10.1124/Mol.119.118653  0.638
2020 Zhang J, Yu Z, You G. Insulin-like growth factor 1 modulates the phosphorylation, expression, and activity of organic anion transporter 3 through protein kinase A signaling pathway. Acta Pharmaceutica Sinica. B. 10: 186-194. PMID 31993315 DOI: 10.1016/j.apsb.2019.05.005  0.415
2019 Wang H, You G. The SUMO-specific protease Senp2 regulates SUMOylation, expression and function of human organic anion transporter 3. Biochimica Et Biophysica Acta. Biomembranes. PMID 31054272 DOI: 10.1016/j.bbamem.2019.04.007  0.603
2019 Liu C, Zhang J, You G. Interaction of Anticancer Drugs with Human Organic Anion Transporter hOAT4. Journal of Oncology. 2019: 1951786. PMID 30941173 DOI: 10.1155/2019/1951786  0.461
2019 Wang H, Zhang J, You G. Activation of Protein Kinase A Stimulates SUMOylation, Expression, and Transport Activity of Organic Anion Transporter 3. The Aaps Journal. 21: 30. PMID 30761470 DOI: 10.1208/S12248-019-0303-4  0.598
2018 Wang H, Zhang J, You G. The Mechanistic Links between Insulin and Human Organic Anion Transporter 4. International Journal of Pharmaceutics. PMID 30453017 DOI: 10.1016/J.Ijpharm.2018.11.040  0.467
2018 Zhang J, Liu C, You G. AG490, a JAK2-specific inhibitor, downregulates the expression and activity of organic anion transporter-3. Journal of Pharmacological Sciences. PMID 29487013 DOI: 10.1016/J.Jphs.2018.01.006  0.6
2018 Wang H, Liu C, You G. The activity of organic anion transporter-3: Role of dexamethasone. Journal of Pharmacological Sciences. PMID 29422382 DOI: 10.1016/J.Jphs.2017.12.011  0.645
2017 Wang H, You G. SGK1/Nedd4-2 signaling pathway regulates the activity of Human Organic Anion Transporters 3. Biopharmaceutics & Drug Disposition. PMID 28608480 DOI: 10.1002/bdd.2085  0.614
2017 Xu D, Zhang J, Zhang Q, Fan Y, Liu C, You G. PKC/Nedd4-2 Signaling Pathway Regulates the Cell Surface Expression of Drug Transporter hOAT1. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 28572241 DOI: 10.1124/Dmd.117.075861  0.567
2016 Xu D, Huang H, Toh MF, You G. Serum- and glucocorticoid-inducible kinase sgk2 stimulates the transport activity of human organic anion transporters 1 by enhancing the stability of the transporter. International Journal of Biochemistry and Molecular Biology. 7: 19-26. PMID 27335683  0.602
2016 Toh MF, Suh W, Wang H, Zhou P, Hu L, You G. Inhibitory effects of chemotherapeutics on human organic anion transporter hOAT4. International Journal of Biochemistry and Molecular Biology. 7: 11-8. PMID 27335682  0.517
2016 Xu D, Wang H, You G. Posttranslational Regulation of Organic Anion Transporters by Ubiquitination: Known and Novel. Medicinal Research Reviews. PMID 27291023 DOI: 10.1002/Med.21397  0.547
2016 Xu D, Wang H, Gardner CR, Pan Z, Zhang PL, Zhang J, You G. The Role of Nedd4-1 WW Domains in Binding and Regulating Human Organic anion Transporter 1. American Journal of Physiology. Renal Physiology. ajprenal.00153.2016. PMID 27226107 DOI: 10.1152/Ajprenal.00153.2016  0.614
2016 Xu D, You G. Loops and Layers of post-translational modifications of drug transporters. Advanced Drug Delivery Reviews. PMID 27174152 DOI: 10.1016/j.addr.2016.05.003  0.52
2016 Xu D, Wang H, Zhang Q, You G. Nedd4-2 but not Nedd4-1 is Critical for Protein Kinase C-Regulated Ubiquitination, Expression and Transport Activity of Human Organic Anion Transporter 1. American Journal of Physiology. Renal Physiology. ajprenal.00522.2015. PMID 26823285 DOI: 10.1152/Ajprenal.00522.2015  0.665
2015 Wang H, Xu D, Toh MF, Pao AC, You G. Serum- and Glucocorticoid-Inducible Kinase SGK2 Regulates Human Organic Anion Transporters 4 via Ubiquitin Ligase Nedd4-2. Biochemical Pharmacology. PMID 26740304 DOI: 10.1016/J.Bcp.2015.11.024  0.673
2015 Xu D, Wang H, You G. An Essential Role of Nedd4-2 in the Ubiquitination, Expression and Function of Organic Anion Transporter-3. Molecular Pharmaceutics. PMID 26651153 DOI: 10.1021/Acs.Molpharmaceut.5B00839  0.665
2014 You G, Morris ME. Drug Transporters: Molecular Characterization and Role in Drug Disposition: Second Edition Drug Transporters: Molecular Characterization and Role in Drug Disposition: Second Edition. 1-495. DOI: 10.1002/9781118705308  0.424
2013 Li S, Zhang Q, You G. Three ubiquitination sites of organic anion transporter-1 synergistically mediate protein kinase C-dependent endocytosis of the transporter. Molecular Pharmacology. 84: 139-46. PMID 23640180 DOI: 10.1124/Mol.113.086769  0.639
2013 Zhang Q, Li S, Patterson C, You G. Lysine 48-linked polyubiquitination of organic anion transporter-1 is essential for its protein kinase C-regulated endocytosis. Molecular Pharmacology. 83: 217-24. PMID 23087261 DOI: 10.1124/Mol.112.082065  0.569
2012 Duan P, Li S, You G. Regulation of human organic anion transporter 4 by parathyroid hormone-related protein and protein kinase A. International Journal of Biochemistry and Molecular Biology. 3: 322-7. PMID 23097748  0.568
2012 Duan P, Li S, Ai N, Hu L, Welsh WJ, You G. Potent inhibitors of human organic anion transporters 1 and 3 from clinical drug libraries: discovery and molecular characterization. Molecular Pharmaceutics. 9: 3340-6. PMID 22973893 DOI: 10.1021/Mp300365T  0.45
2012 Zhang Q, Suh W, Pan Z, You G. Short-term and long-term effects of protein kinase C on the trafficking and stability of human organic anion transporter 3. International Journal of Biochemistry and Molecular Biology. 3: 242-9. PMID 22773962  0.439
2012 Duan P, Li S, You G. Regulation of human organic anion transporter 4 by parathyroid hormone-related protein and protein kinase A International Journal of Biochemistry and Molecular Biology. 3: 322-327.  0.568
2011 Zhang Q, Wu J, Pan Z, You G. The Role of Dileucine in the Expression and Function of Human Organic Anion Transporter 1 (hOAT1). International Journal of Biochemistry and Molecular Biology. 2: 31-38. PMID 21494320  0.592
2011 Duan P, Wu J, You G. Mutational analysis of the role of GXXXG motif in the function of human organic anion transporter 1 (hOAT1). International Journal of Biochemistry and Molecular Biology. 2: 1-7. PMID 21340049  0.524
2011 Duan P, Li S, You G. Transmembrane peptide as potent inhibitor of oligomerization and function of human organic anion transporter 1. Molecular Pharmacology. 79: 569-74. PMID 21159999 DOI: 10.1124/Mol.110.070185  0.518
2011 Zhang Q, Wu J, Pan Z, You G. Original article the role of dileucine in the expression and function of human organic anion transporter 1 (hOAT1) International Journal of Biochemistry and Molecular Biology. 2: 31-38.  0.592
2011 Duan P, Wu J, You G. Mutational analysis of the role of GXXXG motif in the function of human organic anion transporter 1 (hOAT1) International Journal of Biochemistry and Molecular Biology. 2: 1-7.  0.524
2010 Li S, Duan P, You G. Regulation of human organic anion transporter 3 by peptide hormone bradykinin. The Journal of Pharmacology and Experimental Therapeutics. 333: 970-5. PMID 20299424 DOI: 10.1124/Jpet.110.165472  0.586
2010 Zhang Q, Pan Z, You G. Regulation of human organic anion transporter 4 by protein kinase C and NHERF-1: altering the endocytosis of the transporter. Pharmaceutical Research. 27: 589-96. PMID 20140636 DOI: 10.1007/S11095-009-9983-2  0.627
2010 Hong M, Li S, Zhou F, Thomas PE, You G. Putative transmembrane domain 12 of the human organic anion transporter hOAT1 determines transporter stability and maturation efficiency. The Journal of Pharmacology and Experimental Therapeutics. 332: 650-8. PMID 19892921 DOI: 10.1124/Jpet.109.160515  0.731
2010 Duan P, Li S, You G. Angiotensin II inhibits activity of human organic anion transporter 3 through activation of protein kinase Calpha: accelerating endocytosis of the transporter. European Journal of Pharmacology. 627: 49-55. PMID 19878671 DOI: 10.1016/J.Ejphar.2009.10.048  0.547
2010 Duan P, You G. Short-term regulation of organic anion transporters. Pharmacology & Therapeutics. 125: 55-61. PMID 19744520 DOI: 10.1016/J.Pharmthera.2009.08.002  0.542
2010 Zhou F, Duan P, You G. The Role of Membrane Transporters in Drug Disposition Evaluation of Drug Candidates For Preclinical Development: Pharmacokinetics, Metabolism, Pharmaceutics, and Toxicology. 39-53. DOI: 10.1002/9780470574898.ch3  0.44
2009 Duan P, You G. Novobiocin is a potent inhibitor for human organic anion transporters. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 37: 1203-10. PMID 19282394 DOI: 10.1124/Dmd.109.026880  0.417
2009 Li S, Duan P, You G. Regulation of human organic anion transporter 1 by ANG II: involvement of protein kinase Calpha. American Journal of Physiology. Endocrinology and Metabolism. 296: E378-83. PMID 19088254 DOI: 10.1152/Ajpendo.90713.2008  0.528
2008 Zhang Q, Hong M, Duan P, Pan Z, Ma J, You G. Organic anion transporter OAT1 undergoes constitutive and protein kinase C-regulated trafficking through a dynamin- and clathrin-dependent pathway. The Journal of Biological Chemistry. 283: 32570-9. PMID 18818201 DOI: 10.1074/Jbc.M800298200  0.595
2008 You G. Membrane transporters in drug disposition. Pharmaceutical Research. 25: 441-3. PMID 17846868 DOI: 10.1007/S11095-007-9437-7  0.506
2008 Zhou F, Xu W, Tanaka K, You G. Comparison of the interaction of human organic anion transporter hOAT4 with PDZ proteins between kidney cells and placental cells. Pharmaceutical Research. 25: 475-80. PMID 17602283 DOI: 10.1007/S11095-007-9359-4  0.655
2007 Zhou F, Hong M, You G. Regulation of human organic anion transporter 4 by progesterone and protein kinase C in human placental BeWo cells. American Journal of Physiology. Endocrinology and Metabolism. 293: E57-61. PMID 17341544 DOI: 10.1152/Ajpendo.00696.2006  0.714
2007 Hong M, Zhou F, Lee K, You G. The putative transmembrane segment 7 of human organic anion transporter hOAT1 dictates transporter substrate binding and stability. The Journal of Pharmacology and Experimental Therapeutics. 320: 1209-15. PMID 17167169 DOI: 10.1124/Jpet.106.117663  0.739
2007 Zhou F, You G. Molecular insights into the structure-function relationship of organic anion transporters OATs. Pharmaceutical Research. 24: 28-36. PMID 17103332 DOI: 10.1007/S11095-006-9144-9  0.653
2007 Hong M, Tanaka K, Pan Z, Ma J, You G. Determination of the external loops and the cellular orientation of the N- and the C-termini of the human organic anion transporter hOAT1. The Biochemical Journal. 401: 515-20. PMID 17014423 DOI: 10.1042/Bj20061171  0.535
2006 Xu W, Tanaka K, Sun AQ, You G. Functional role of the C terminus of human organic anion transporter hOAT1. The Journal of Biological Chemistry. 281: 31178-83. PMID 16920720 DOI: 10.1074/Jbc.M605664200  0.592
2006 Zhou F, Illsley NP, You G. Functional characterization of a human organic anion transporter hOAT4 in placental BeWo cells. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 27: 518-23. PMID 16257192 DOI: 10.1016/J.Ejps.2005.09.008  0.725
2006 Hong M, You G. Regulation of Drug Transporter Activity Drug Transporters: Molecular Characterization and Role in Drug Disposition. 517-531. DOI: 10.1002/9780470140505.ch17  0.471
2006 You G, Morris ME. Overview of Drug Transporter Families Drug Transporters: Molecular Characterization and Role in Drug Disposition. 1-10. DOI: 10.1002/9780470140505.ch1  0.384
2005 Hong M, Xu W, Yoshida T, Tanaka K, Wolff DJ, Zhou F, Inouye M, You G. Human organic anion transporter hOAT1 forms homooligomers. The Journal of Biological Chemistry. 280: 32285-90. PMID 16046403 DOI: 10.1074/Jbc.M501447200  0.672
2005 Zhou F, Xu W, Hong M, Pan Z, Sinko PJ, Ma J, You G. The role of N-linked glycosylation in protein folding, membrane targeting, and substrate binding of human organic anion transporter hOAT4. Molecular Pharmacology. 67: 868-76. PMID 15576633 DOI: 10.1124/Mol.104.007583  0.65
2004 Zhou F, Pan Z, Ma J, You G. Mutational analysis of histidine residues in human organic anion transporter 4 (hOAT4). The Biochemical Journal. 384: 87-92. PMID 15291761 DOI: 10.1042/Bj20040751  0.752
2004 You G. Towards an understanding of organic anion transporters: structure-function relationships. Medicinal Research Reviews. 24: 762-74. PMID 15250040 DOI: 10.1002/Med.20014  0.579
2004 Hong M, Zhou F, You G. Critical amino acid residues in transmembrane domain 1 of the human organic anion transporter hOAT1. The Journal of Biological Chemistry. 279: 31478-82. PMID 15145940 DOI: 10.1074/Jbc.M404686200  0.731
2004 Zhou F, Tanaka K, Pan Z, Ma J, You G. The role of glycine residues in the function of human organic anion transporter 4. Molecular Pharmacology. 65: 1141-7. PMID 15102942 DOI: 10.1124/Mol.65.5.1141  0.716
2004 Tanaka K, Zhou F, Kuze K, You G. Cysteine residues in the organic anion transporter mOAT1. The Biochemical Journal. 380: 283-7. PMID 14979872 DOI: 10.1042/Bj20031724  0.737
2004 You G. The role of organic ion transporters in drug disposition: an update. Current Drug Metabolism. 5: 55-62. PMID 14965250 DOI: 10.2174/1389200043489207  0.475
2004 Tanaka K, Xu W, Zhou F, You G. Role of glycosylation in the organic anion transporter OAT1. The Journal of Biological Chemistry. 279: 14961-6. PMID 14749323 DOI: 10.1074/Jbc.M400197200  0.746
2003 Zhou F, Tanaka K, Soares MJ, You G. Characterization of an organic anion transport system in a placental cell line. American Journal of Physiology. Endocrinology and Metabolism. 285: E1103-9. PMID 12902320 DOI: 10.1152/Ajpendo.00182.2003  0.722
2002 You G. Structure, function, and regulation of renal organic anion transporters. Medicinal Research Reviews. 22: 602-16. PMID 12369090 DOI: 10.1002/Med.10019  0.559
2000 You G, Kuze K, Kohanski RA, Amsler K, Henderson S. Regulation of mOAT-mediated organic anion transport by okadaic acid and protein kinase C in LLC-PK1 cells Journal of Biological Chemistry. 275: 10278-10284. PMID 10744714 DOI: 10.1074/jbc.275.14.10278  0.516
1999 Kuze K, Graves P, Leahy A, Wilson P, Stuhlmann H, You G. Heterologous expression and functional characterization of a mouse renal organic anion transporter in mammalian cells. The Journal of Biological Chemistry. 274: 1519-24. PMID 9880528 DOI: 10.1074/jbc.274.3.1519  0.622
1996 Martial S, Olivès B, Abrami L, Couriaud C, Bailly P, You G, Hediger MA, Cartron JP, Ripoche P, Rousselet G. Functional differentiation of the human red blood cell and kidney urea transporters. The American Journal of Physiology. 271: F1264-8. PMID 8997401 DOI: 10.1152/ajprenal.1996.271.6.F1264  0.463
1995 Hediger MA, Kanai Y, You G, Nussberger S. Mammalian ion‐coupled solute transporters The Journal of Physiology. 482: 7-17. PMID 7730974 DOI: 10.1113/jphysiol.1995.sp020559  0.494
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