Robert T. Dorsam, Ph.D. - Publications

Affiliations: 
2004 Temple University, Philadelphia, PA, United States 
Area:
Pharmacology

20 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Vaqué JP, Dorsam RT, Feng X, Iglesias-Bartolome R, Forsthoefel DJ, Chen Q, Debant A, Seeger MA, Ksander BR, Teramoto H, Gutkind JS. A genome-wide RNAi screen reveals a Trio-regulated Rho GTPase circuitry transducing mitogenic signals initiated by G protein-coupled receptors. Molecular Cell. 49: 94-108. PMID 23177739 DOI: 10.1016/j.molcel.2012.10.018  0.379
2011 Bhavaraju K, Lakhani PR, Dorsam RT, Jin J, Hitchcock IS, Sanjay A, Kunapuli SP. G(12/13) signaling pathways substitute for integrin αIIbβ3-signaling for thromboxane generation in platelets. Plos One. 6: e16586. PMID 21347357 DOI: 10.1371/Journal.Pone.0016586  0.755
2008 Kahner BN, Dorsam RT, Kim S, Shankar H, Kitamura D, Kunapuli SP. Hematopoietic lineage cell-specific protein-1 (HS1) regulates PAR-mediated ERK activation and thromboxane generation in platelets. Platelets. 19: 614-23. PMID 19012179 DOI: 10.1080/09537100802351057  0.756
2008 Kahner BN, Dorsam RT, Kunapuli SP. Role of P2Y receptor subtypes in platelet-derived microparticle generation. Frontiers in Bioscience : a Journal and Virtual Library. 13: 433-9. PMID 17981558 DOI: 10.2741/2690  0.708
2007 Kahner BN, Dorsam RT, Mada SR, Kim S, Stalker TJ, Brass LF, Daniel JL, Kitamura D, Kunapuli SP. Hematopoietic lineage cell specific protein 1 (HS1) is a functionally important signaling molecule in platelet activation. Blood. 110: 2449-56. PMID 17579181 DOI: 10.1182/Blood-2006-11-056069  0.731
2005 Garcia A, Quinton TM, Dorsam RT, Kunapuli SP. Src family kinase-mediated and Erk-mediated thromboxane A2 generation are essential for VWF/GPIb-induced fibrinogen receptor activation in human platelets. Blood. 106: 3410-4. PMID 16020504 DOI: 10.1182/Blood-2005-05-1933  0.731
2005 Murugappan S, Shankar H, Bhamidipati S, Dorsam RT, Jin J, Kunapuli SP. Molecular mechanism and functional implications of thrombin-mediated tyrosine phosphorylation of PKCdelta in platelets. Blood. 106: 550-7. PMID 15811957 DOI: 10.1182/Blood-2004-12-4866  0.755
2005 Dorsam RT, Kim S, Murugappan S, Rachoor S, Shankar H, Jin J, Kunapuli SP. Differential requirements for calcium and Src family kinases in platelet GPIIb/IIIa activation and thromboxane generation downstream of different G-protein pathways. Blood. 105: 2749-56. PMID 15546949 DOI: 10.1182/Blood-2004-07-2821  0.75
2004 Dorsam RT, Tuluc M, Kunapuli SP. Role of protease-activated and ADP receptor subtypes in thrombin generation on human platelets. Journal of Thrombosis and Haemostasis : Jth. 2: 804-12. PMID 15099288 DOI: 10.1111/J.1538-7836.2004.00692.X  0.692
2004 Dorsam RT, Kunapuli SP. Central role of the P2Y12 receptor in platelet activation. The Journal of Clinical Investigation. 113: 340-5. PMID 14755328 DOI: 10.1172/Jci20986  0.704
2004 Murugappan S, Tuluc F, Dorsam RT, Shankar H, Kunapuli SP. Differential role of protein kinase C delta isoform in agonist-induced dense granule secretion in human platelets. The Journal of Biological Chemistry. 279: 2360-7. PMID 14578358 DOI: 10.1074/Jbc.M306960200  0.777
2004 Kahner BN, Dorsam RT, Kunapuli SP. Both Platelet ADP Receptors Contribute to Microparticle Formation. Blood. 104: 3876-3876. DOI: 10.1182/Blood.V104.11.3876.3876  0.71
2003 Dorsam RT, Murugappan S, Ding Z, Kunapuli SP. Clopidogrel: interactions with the P2Y12 receptor and clinical relevance. Hematology (Amsterdam, Netherlands). 8: 359-65. PMID 14668029 DOI: 10.1080/10245330310001621260  0.662
2003 Kunapuli SP, Ding Z, Dorsam RT, Kim S, Murugappan S, Quinton TM. ADP receptors--targets for developing antithrombotic agents. Current Pharmaceutical Design. 9: 2303-16. PMID 14529392 DOI: 10.2174/1381612033453947  0.764
2003 Kunapuli SP, Dorsam RT, Kim S, Quinton TM. Platelet purinergic receptors. Current Opinion in Pharmacology. 3: 175-80. PMID 12681240 DOI: 10.1016/S1471-4892(03)00007-9  0.732
2003 Ding Z, Kim S, Dorsam RT, Jin J, Kunapuli SP. Inactivation of the human P2Y12 receptor by thiol reagents requires interaction with both extracellular cysteine residues, Cys17 and Cys270. Blood. 101: 3908-14. PMID 12560222 DOI: 10.1182/Blood-2002-10-3027  0.662
2002 Wang X, Dorsam RT, Lauver A, Wang H, Barbera FA, Gibbs S, Varon D, Savion N, Friedman SM, Feuerstein GZ. Comparative analysis of various platelet glycoprotein IIb/IIIa antagonists on shear-induced platelet activation and adhesion. The Journal of Pharmacology and Experimental Therapeutics. 303: 1114-20. PMID 12438534 DOI: 10.1124/jpet.102.038513  0.477
2002 Dorsam RT, Kim S, Jin J, Kunapuli SP. Coordinated signaling through both G12/13 and G(i) pathways is sufficient to activate GPIIb/IIIa in human platelets. The Journal of Biological Chemistry. 277: 47588-95. PMID 12297512 DOI: 10.1074/Jbc.M208778200  0.675
2002 Quinton TM, Kim S, Dangelmaier C, Dorsam RT, Jin J, Daniel JL, Kunapuli SP. Protein kinase C- and calcium-regulated pathways independently synergize with Gi pathways in agonist-induced fibrinogen receptor activation. The Biochemical Journal. 368: 535-43. PMID 12215172 DOI: 10.1042/Bj20020226  0.756
2000 Quinton TM, Dangelmaier C, Dorsam RT, Jin J, Daniel JL, Kunapuli SP. Calcium-sensitive and protein kinase C-sensitive pathways independently mediate agonist-induced fibrinogen receptor activation in human platelets Blood. 96: 247a.  0.681
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