Robert A. Weinberg, Ph.D. - Publications

Affiliations: 
Biology Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
oncogenes
Website:
https://biology.mit.edu/people/robert_weinberg

232 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Kröger C, Afeyan A, Mraz J, Eaton EN, Reinhardt F, Khodor YL, Thiru P, Bierie B, Ye X, Burge CB, Weinberg RA. Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 30910979 DOI: 10.1073/pnas.1812876116  0.84
2018 Castaño Z, San Juan BP, Spiegel A, Pant A, DeCristo MJ, Laszewski T, Ubellacker JM, Janssen SR, Dongre A, Reinhardt F, Henderson A, Del Rio AG, Gifford AM, Herbert ZT, Hutchinson JN, ... Weinberg RA, et al. IL-1β inflammatory response driven by primary breast cancer prevents metastasis-initiating cell colonization. Nature Cell Biology. 20: 1084-1097. PMID 30154549 DOI: 10.1038/s41556-018-0173-5  0.52
2018 Li J, Choi PS, Chaffer CL, Labella K, Hwang JH, Giacomelli AO, Kim JW, Ilic N, Doench JG, Ly SH, Dai C, Hagel K, Hong AL, Gjoerup O, Goel S, ... ... Weinberg RA, et al. An alternative splicing switch in FLNB promotes the mesenchymal cell state in human breast cancer. Elife. 7. PMID 30059005 DOI: 10.7554/eLife.37184  0.32
2018 Zhang Y, Weinberg RA. Epithelial-to-mesenchymal transition in cancer: complexity and opportunities. Frontiers of Medicine. PMID 30043221 DOI: 10.1007/s11684-018-0656-6  1
2018 Krall JA, Reinhardt F, Mercury OA, Pattabiraman DR, Brooks MW, Dougan M, Lambert AW, Bierie B, Ploegh HL, Dougan SK, Weinberg RA. The systemic response to surgery triggers the outgrowth of distant immune-controlled tumors in mouse models of dormancy. Science Translational Medicine. 10. PMID 29643230 DOI: 10.1126/scitranslmed.aan3464  0.36
2017 Keckesova Z, Donaher JL, De Cock J, Freinkman E, Lingrell S, Bachovchin DA, Bierie B, Tischler V, Noske A, Okondo MC, Reinhardt F, Thiru P, Golub TR, Vance JE, Weinberg RA. LACTB is a tumour suppressor that modulates lipid metabolism and cell state. Nature. PMID 28329758 DOI: 10.1038/nature21408  0.36
2017 Bierie B, Pierce SE, Kroeger C, Stover DG, Pattabiraman DR, Thiru P, Liu Donaher J, Reinhardt F, Chaffer CL, Keckesova Z, Weinberg RA. Integrin-β4 identifies cancer stem cell-enriched populations of partially mesenchymal carcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28270621 DOI: 10.1073/pnas.1618298114  0.52
2016 Spiegel A, Brooks MW, Houshyar S, Reinhardt F, Ardolino M, Fessler E, Chen MB, Krall JA, DeCock J, Zervantonakis IK, Iannello A, Iwamoto Y, Cortez-Retamozo V, Kamm RD, Pittet MJ, ... ... Weinberg RA, et al. Neutrophils suppress intraluminal NK-mediated tumor cell clearance and enhance extravasation of disseminated carcinoma cells. Cancer Discovery. PMID 27072748 DOI: 10.1158/2159-8290.CD-15-1157  0.36
2016 Pattabiraman DR, Bierie B, Kober KI, Thiru P, Krall JA, Zill C, Reinhardt F, Tam WL, Weinberg RA. Activation of PKA leads to mesenchymal-to-epithelial transition and loss of tumor-initiating ability. Science (New York, N.Y.). 351: aad3680. PMID 26941323 DOI: 10.1126/science.aad3680  1
2015 Lu H, Clauser KR, Tam WL, Fröse J, Ye X, Eaton EN, Reinhardt F, Donnenberg VS, Bhargava R, Carr SA, Weinberg RA. Addendum: A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages. Nature Cell Biology. 17: 1607. PMID 26612575 DOI: 10.1038/ncb3281  0.84
2015 Ye X, Weinberg RA. Epithelial-Mesenchymal Plasticity: A Central Regulator of Cancer Progression. Trends in Cell Biology. 25: 675-86. PMID 26437589 DOI: 10.1016/j.tcb.2015.07.012  1
2015 Ye X, Tam WL, Shibue T, Kaygusuz Y, Reinhardt F, Ng Eaton E, Weinberg RA. Distinct EMT programs control normal mammary stem cells and tumour-initiating cells. Nature. 525: 256-60. PMID 26331542 DOI: 10.1038/nature14897  1
2015 Watnick RS, Rodriguez RK, Wang S, Blois AL, Rangarajan A, Ince T, Weinberg RA. Thrombospondin-1 repression is mediated via distinct mechanisms in fibroblasts and epithelial cells. Oncogene. 34: 2949-50. PMID 26020734 DOI: 10.1038/onc.2015.183  1
2015 Katajisto P, Döhla J, Chaffer CL, Pentinmikko N, Marjanovic N, Iqbal S, Zoncu R, Chen W, Weinberg RA, Sabatini DM. Stem cells. Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness. Science (New York, N.Y.). 348: 340-3. PMID 25837514 DOI: 10.1126/science.1260384  1
2015 Chaffer CL, Weinberg RA. How does multistep tumorigenesis really proceed? Cancer Discovery. 5: 22-4. PMID 25583800 DOI: 10.1158/2159-8290.CD-14-0788  1
2015 Watnick RS, Rodriguez RK, Wang S, Blois AL, Rangarajan A, Ince T, Weinberg RA. Thrombospondin-1 repression is mediated via distinct mechanisms in fibroblasts and epithelial cells. Oncogene. 34: 2823-35. PMID 25109329 DOI: 10.1038/onc.2014.228  1
2014 Unternaehrer JJ, Zhao R, Kim K, Cesana M, Powers JT, Ratanasirintrawoot S, Onder T, Shibue T, Weinberg RA, Daley GQ. The epithelial-mesenchymal transition factor SNAIL paradoxically enhances reprogramming. Stem Cell Reports. 3: 691-8. PMID 25316190 DOI: 10.1016/j.stemcr.2014.09.008  1
2014 Lu H, Clauser KR, Tam WL, Fröse J, Ye X, Eaton EN, Reinhardt F, Donnenberg VS, Bhargava R, Carr SA, Weinberg RA. A breast cancer stem cell niche supported by juxtacrine signalling from monocytes and macrophages. Nature Cell Biology. 16: 1105-17. PMID 25266422 DOI: 10.1038/ncb3041  1
2014 Shaul YD, Freinkman E, Comb WC, Cantor JR, Tam WL, Thiru P, Kim D, Kanarek N, Pacold ME, Chen WW, Bierie B, Possemato R, Reinhardt F, Weinberg RA, Yaffe MB, et al. Dihydropyrimidine accumulation is required for the epithelial-mesenchymal transition. Cell. 158: 1094-109. PMID 25171410 DOI: 10.1016/j.cell.2014.07.032  1
2014 McAllister SS, Weinberg RA. The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis. Nature Cell Biology. 16: 717-27. PMID 25082194 DOI: 10.1038/ncb3015  1
2014 Pattabiraman DR, Weinberg RA. Tackling the cancer stem cells - what challenges do they pose? Nature Reviews. Drug Discovery. 13: 497-512. PMID 24981363 DOI: 10.1038/nrd4253  1
2014 Weinberg RA. Coming full circle-from endless complexity to simplicity and back again. Cell. 157: 267-71. PMID 24679541 DOI: 10.1016/j.cell.2014.03.004  1
2014 Hahn WC, Weinberg RA. Cancer: A Genetic Disorder The Molecular Basis of Cancer: Fourth Edition. 3-18.e1. DOI: 10.1016/B978-1-4557-4066-6.00001-9  0.56
2013 Tam WL, Weinberg RA. The epigenetics of epithelial-mesenchymal plasticity in cancer. Nature Medicine. 19: 1438-49. PMID 24202396 DOI: 10.1038/nm.3336  1
2013 Tam WL, Lu H, Buikhuisen J, Soh BS, Lim E, Reinhardt F, Wu ZJ, Krall JA, Bierie B, Guo W, Chen X, Liu XS, Brown M, Lim B, Weinberg RA. Protein kinase C α is a central signaling node and therapeutic target for breast cancer stem cells. Cancer Cell. 24: 347-64. PMID 24029232 DOI: 10.1016/j.ccr.2013.08.005  1
2013 Marjanovic ND, Weinberg RA, Chaffer CL. Poised with purpose: cell plasticity enhances tumorigenicity. Cell Cycle (Georgetown, Tex.). 12: 2713-4. PMID 23966153 DOI: 10.4161/cc.26075  1
2013 Chaffer CL, Marjanovic ND, Lee T, Bell G, Kleer CG, Reinhardt F, D'Alessio AC, Young RA, Weinberg RA. Poised chromatin at the ZEB1 promoter enables breast cancer cell plasticity and enhances tumorigenicity. Cell. 154: 61-74. PMID 23827675 DOI: 10.1016/j.cell.2013.06.005  1
2013 Marjanovic ND, Weinberg RA, Chaffer CL. Cell plasticity and heterogeneity in cancer. Clinical Chemistry. 59: 168-79. PMID 23220226 DOI: 10.1373/clinchem.2012.184655  1
2013 Watnick RS, Cheng YN, Rangarajan A, Ince TA, Weinberg RA. Ras Modulates Myc Activity to Repress Thrombospondin-1 Expression and Increase Tumor Angiogenesis Cancer Cell. 23: 129. DOI: 10.1016/j.ccr.2012.11.004  1
2012 Li HJ, Reinhardt F, Herschman HR, Weinberg RA. Cancer-stimulated mesenchymal stem cells create a carcinoma stem cell niche via prostaglandin E2 signaling. Cancer Discovery. 2: 840-55. PMID 22763855 DOI: 10.1158/2159-8290.CD-12-0101  1
2012 Shibue T, Brooks MW, Inan MF, Reinhardt F, Weinberg RA. The outgrowth of micrometastases is enabled by the formation of filopodium-like protrusions. Cancer Discovery. 2: 706-21. PMID 22609699 DOI: 10.1158/2159-8290.CD-11-0239  1
2012 Scheel C, Weinberg RA. Cancer stem cells and epithelial-mesenchymal transition: concepts and molecular links. Seminars in Cancer Biology. 22: 396-403. PMID 22554795 DOI: 10.1016/j.semcancer.2012.04.001  1
2012 Guo W, Keckesova Z, Donaher JL, Shibue T, Tischler V, Reinhardt F, Itzkovitz S, Noske A, Zürrer-Härdi U, Bell G, Tam WL, Mani SA, van Oudenaarden A, Weinberg RA. Slug and Sox9 cooperatively determine the mammary stem cell state. Cell. 148: 1015-28. PMID 22385965 DOI: 10.1016/j.cell.2012.02.008  1
2011 Valastyan S, Weinberg RA. Tumor metastasis: molecular insights and evolving paradigms. Cell. 147: 275-92. PMID 22000009 DOI: 10.1016/j.cell.2011.09.024  1
2011 Weinberg RA. Hunting the elusive oncogene: a stroke of good luck. Nature Cell Biology. 13: 876. PMID 21808240 DOI: 10.1038/ncb2302  1
2011 Scheel C, Weinberg RA. Phenotypic plasticity and epithelial-mesenchymal transitions in cancer and normal stem cells? International Journal of Cancer. Journal International Du Cancer. 129: 2310-4. PMID 21792896 DOI: 10.1002/ijc.26311  1
2011 Scheel C, Eaton EN, Li SH, Chaffer CL, Reinhardt F, Kah KJ, Bell G, Guo W, Rubin J, Richardson AL, Weinberg RA. Paracrine and autocrine signals induce and maintain mesenchymal and stem cell states in the breast. Cell. 145: 926-40. PMID 21663795 DOI: 10.1016/j.cell.2011.04.029  1
2011 Chaffer CL, Brueckmann I, Scheel C, Kaestli AJ, Wiggins PA, Rodrigues LO, Brooks M, Reinhardt F, Su Y, Polyak K, Arendt LM, Kuperwasser C, Bierie B, Weinberg RA. Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state. Proceedings of the National Academy of Sciences of the United States of America. 108: 7950-5. PMID 21498687 DOI: 10.1073/pnas.1102454108  1
2011 Chaffer CL, Weinberg RA. A perspective on cancer cell metastasis. Science (New York, N.Y.). 331: 1559-64. PMID 21436443 DOI: 10.1126/science.1203543  1
2011 Valastyan S, Chang A, Benaich N, Reinhardt F, Weinberg RA. Activation of miR-31 function in already-established metastases elicits metastatic regression. Genes & Development. 25: 646-59. PMID 21406558 DOI: 10.1101/gad.2004211  1
2011 Valastyan S, Weinberg RA. Roles for microRNAs in the regulation of cell adhesion molecules. Journal of Cell Science. 124: 999-1006. PMID 21402873 DOI: 10.1242/jcs.081513  1
2011 Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell. 144: 646-74. PMID 21376230 DOI: 10.1016/j.cell.2011.02.013  1
2011 Elkabets M, Gifford AM, Scheel C, Nilsson B, Reinhardt F, Bray MA, Carpenter AE, Jirström K, Magnusson K, Ebert BL, Pontén F, Weinberg RA, McAllister SS. Human tumors instigate granulin-expressing hematopoietic cells that promote malignancy by activating stromal fibroblasts in mice. The Journal of Clinical Investigation. 121: 784-99. PMID 21266779 DOI: 10.1172/JCI43757  1
2011 Shibue T, Weinberg RA. Metastatic colonization: settlement, adaptation and propagation of tumor cells in a foreign tissue environment. Seminars in Cancer Biology. 21: 99-106. PMID 21145969 DOI: 10.1016/j.semcancer.2010.12.003  1
2011 Rai P, Young JJ, Burton DG, Giribaldi MG, Onder TT, Weinberg RA. Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and premature senescence. Oncogene. 30: 1489-96. PMID 21076467 DOI: 10.1038/onc.2010.520  1
2010 Valastyan S, Weinberg RA. Metastasis suppression: a role of the Dice(r). Genome Biology. 11: 141. PMID 21118581 DOI: 10.1186/gb-2010-11-11-141  1
2010 Kojima Y, Acar A, Eaton EN, Mellody KT, Scheel C, Ben-Porath I, Onder TT, Wang ZC, Richardson AL, Weinberg RA, Orimo A. Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 107: 20009-14. PMID 21041659 DOI: 10.1073/pnas.1013805107  1
2010 Roussos ET, Keckesova Z, Haley JD, Epstein DM, Weinberg RA, Condeelis JS. AACR special conference on epithelial-mesenchymal transition and cancer progression and treatment. Cancer Research. 70: 7360-4. PMID 20823151 DOI: 10.1158/0008-5472.CAN-10-1208  1
2010 Chaffer CL, Weinberg RA. Cancer cell of origin: spotlight on luminal progenitors. Cell Stem Cell. 7: 271-2. PMID 20804960 DOI: 10.1016/j.stem.2010.08.008  1
2010 Taube JH, Herschkowitz JI, Komurov K, Zhou AY, Gupta S, Yang J, Hartwell K, Onder TT, Gupta PB, Evans KW, Hollier BG, Ram PT, Lander ES, Rosen JM, Weinberg RA, et al. Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes. Proceedings of the National Academy of Sciences of the United States of America. 107: 15449-54. PMID 20713713 DOI: 10.1073/pnas.1004900107  1
2010 McAllister SS, Weinberg RA. Tumor-host interactions: a far-reaching relationship. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 4022-8. PMID 20644094 DOI: 10.1200/JCO.2010.28.4257  1
2010 Valastyan S, Chang A, Benaich N, Reinhardt F, Weinberg RA. Concurrent suppression of integrin alpha5, radixin, and RhoA phenocopies the effects of miR-31 on metastasis. Cancer Research. 70: 5147-54. PMID 20530680 DOI: 10.1158/0008-5472.CAN-10-0410  1
2010 Blick T, Hugo H, Widodo E, Waltham M, Pinto C, Mani SA, Weinberg RA, Neve RM, Lenburg ME, Thompson EW. Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer. Journal of Mammary Gland Biology and Neoplasia. 15: 235-52. PMID 20521089 DOI: 10.1007/s10911-010-9175-z  1
2010 Valastyan S, Weinberg RA. miR-31: a crucial overseer of tumor metastasis and other emerging roles. Cell Cycle (Georgetown, Tex.). 9: 2124-9. PMID 20505365 DOI: 10.4161/cc.9.11.11843  1
2010 Ma L, Reinhardt F, Pan E, Soutschek J, Bhat B, Marcusson EG, Teruya-Feldstein J, Bell GW, Weinberg RA. Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model. Nature Biotechnology. 28: 341-7. PMID 20351690 DOI: 10.1038/nbt.1618  1
2010 Goldstein RH, Weinberg RA, Rosenblatt M. Of mice and (wo)men: mouse models of breast cancer metastasis to bone. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 431-6. PMID 20200984 DOI: 10.1002/jbmr.68  1
2010 Ma L, Young J, Prabhala H, Pan E, Mestdagh P, Muth D, Teruya-Feldstein J, Reinhardt F, Onder TT, Valastyan S, Westermann F, Speleman F, Vandesompele J, Weinberg RA. miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis. Nature Cell Biology. 12: 247-56. PMID 20173740 DOI: 10.1038/ncb2024  1
2010 Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition (The Journal of Clinical Investigation (2009) 119, 6, (1420-1428) DOI: 10.1172/JCI39104) Journal of Clinical Investigation. 120: 1786. DOI: 10.1172/JCI39104C1  1
2009 Valastyan S, Weinberg RA. Assaying microRNA loss-of-function phenotypes in mammalian cells: emerging tools and their potential therapeutic utility. Rna Biology. 6: 541-5. PMID 19901530  1
2009 Valastyan S, Benaich N, Chang A, Reinhardt F, Weinberg RA. Concomitant suppression of three target genes can explain the impact of a microRNA on metastasis. Genes & Development. 23: 2592-7. PMID 19875476 DOI: 10.1101/gad.1832709  1
2009 Valastyan S, Weinberg RA. MicroRNAs: Crucial multi-tasking components in the complex circuitry of tumor metastasis. Cell Cycle (Georgetown, Tex.). 8: 3506-12. PMID 19838065  1
2009 Gupta PB, Chaffer CL, Weinberg RA. Cancer stem cells: mirage or reality? Nature Medicine. 15: 1010-2. PMID 19734877 DOI: 10.1038/nm0909-1010  1
2009 Gupta PB, Onder TT, Jiang G, Tao K, Kuperwasser C, Weinberg RA, Lander ES. Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell. 138: 645-59. PMID 19682730 DOI: 10.1016/j.cell.2009.06.034  1
2009 Valastyan S, Reinhardt F, Benaich N, Calogrias D, Szász AM, Wang ZC, Brock JE, Richardson AL, Weinberg RA. A pleiotropically acting microRNA, miR-31, inhibits breast cancer metastasis. Cell. 137: 1032-46. PMID 19524507 DOI: 10.1016/j.cell.2009.03.047  1
2009 Shibue T, Weinberg RA. Integrin beta1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs. Proceedings of the National Academy of Sciences of the United States of America. 106: 10290-5. PMID 19502425 DOI: 10.1073/pnas.0904227106  1
2009 Kalluri R, Weinberg RA. The basics of epithelial-mesenchymal transition. The Journal of Clinical Investigation. 119: 1420-8. PMID 19487818 DOI: 10.1172/JCI39104  1
2009 Polyak K, Weinberg RA. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nature Reviews. Cancer. 9: 265-73. PMID 19262571 DOI: 10.1038/nrc2620  1
2009 Rai P, Onder TT, Young JJ, McFaline JL, Pang B, Dedon PC, Weinberg RA. Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence. Proceedings of the National Academy of Sciences of the United States of America. 106: 169-74. PMID 19118192 DOI: 10.1073/pnas.0809834106  1
2009 Shibue T, Weinberg RA. Integrin β1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs (Proceedings of the National Academy of Sciences of the United States of America (2009) 106, 25, (10290-10295) DOI: 10.1073/pnas.0904227106)) Proceedings of the National Academy of Sciences of the United States of America. 106: 14734. DOI: 10.1073/pnas.0908574106  1
2008 Weinberg RA. Leaving home early: reexamination of the canonical models of tumor progression. Cancer Cell. 14: 283-4. PMID 18835030 DOI: 10.1016/j.ccr.2008.09.009  1
2008 Weinberg RA. The many faces of tumor dormancy. Apmis : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. 116: 548-51. PMID 18834401 DOI: 10.1111/j.1600-0463.2008.001168.x  1
2008 Weinberg RA. Twisted epithelial-mesenchymal transition blocks senescence. Nature Cell Biology. 10: 1021-3. PMID 18758491 DOI: 10.1038/ncb0908-1021  1
2008 Weinberg RA, Komaroff AL. Health for life. Your lifestyle, your genes, and cancer. Newsweek. 151: 40-3. PMID 18711886  1
2008 Ma L, Weinberg RA. Micromanagers of malignancy: role of microRNAs in regulating metastasis. Trends in Genetics : Tig. 24: 448-56. PMID 18674843 DOI: 10.1016/j.tig.2008.06.004  1
2008 Godar S, Ince TA, Bell GW, Feldser D, Donaher JL, Bergh J, Liu A, Miu K, Watnick RS, Reinhardt F, McAllister SS, Jacks T, Weinberg RA. Growth-inhibitory and tumor- suppressive functions of p53 depend on its repression of CD44 expression. Cell. 134: 62-73. PMID 18614011 DOI: 10.1016/j.cell.2008.06.006  1
2008 Karnoub AE, Weinberg RA. Ras oncogenes: split personalities. Nature Reviews. Molecular Cell Biology. 9: 517-31. PMID 18568040 DOI: 10.1038/nrm2438  1
2008 McAllister SS, Gifford AM, Greiner AL, Kelleher SP, Saelzler MP, Ince TA, Reinhardt F, Harris LN, Hylander BL, Repasky EA, Weinberg RA. Systemic endocrine instigation of indolent tumor growth requires osteopontin. Cell. 133: 994-1005. PMID 18555776 DOI: 10.1016/j.cell.2008.04.045  1
2008 Yang J, Weinberg RA. Epithelial-mesenchymal transition: at the crossroads of development and tumor metastasis. Developmental Cell. 14: 818-29. PMID 18539112 DOI: 10.1016/j.devcel.2008.05.009  1
2008 Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, Brooks M, Reinhard F, Zhang CC, Shipitsin M, Campbell LL, Polyak K, Brisken C, Yang J, Weinberg RA. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell. 133: 704-15. PMID 18485877 DOI: 10.1016/j.cell.2008.03.027  1
2008 Onder TT, Gupta PB, Mani SA, Yang J, Lander ES, Weinberg RA. Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. Cancer Research. 68: 3645-54. PMID 18483246 DOI: 10.1158/0008-5472.CAN-07-2938  1
2008 Weinberg RA. Mechanisms of malignant progression. Carcinogenesis. 29: 1092-5. PMID 18453542 DOI: 10.1093/carcin/bgn104  1
2008 Ben-Porath I, Thomson MW, Carey VJ, Ge R, Bell GW, Regev A, Weinberg RA. An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors. Nature Genetics. 40: 499-507. PMID 18443585 DOI: 10.1038/ng.127  1
2008 Weinberg RA. Coevolution in the tumor microenvironment. Nature Genetics. 40: 494-5. PMID 18443582 DOI: 10.1038/ng0508-494  1
2008 Hanahan D, Weinberg RA. Retrospective: Judah Folkman (1933-2008). Science (New York, N.Y.). 319: 1055. PMID 18292332 DOI: 10.1126/science.1156080  1
2008 Ma L, Weinberg RA. MicroRNAs in malignant progression. Cell Cycle (Georgetown, Tex.). 7: 570-2. PMID 18256538  1
2008 Ma L, Teruya-Feldstein J, Weinberg RA. Ma et al. reply Nature. 455: E9. DOI: 10.1038/nature07363  1
2008 Ma L, Teruya-Feldstein J, Weinberg RA. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer (Nature (2007) 449, (682-688)) Nature. 455: 256. DOI: 10.1038/nature07316  1
2007 Weinberg RA. Is metastasis predetermined? Molecular Oncology. 1: 263-4; author reply . PMID 19383300 DOI: 10.1016/j.molonc.2007.07.001  1
2007 Scheel C, Onder T, Karnoub A, Weinberg RA. Adaptation versus selection: the origins of metastatic behavior. Cancer Research. 67: 11476-9; discussion . PMID 18089773 DOI: 10.1158/0008-5472.CAN-07-1653  1
2007 Orimo A, Weinberg RA. Heterogeneity of stromal fibroblasts in tumors. Cancer Biology & Therapy. 6: 618-9. PMID 18027438  1
2007 Karnoub AE, Dash AB, Vo AP, Sullivan A, Brooks MW, Bell GW, Richardson AL, Polyak K, Tubo R, Weinberg RA. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature. 449: 557-63. PMID 17914389 DOI: 10.1038/nature06188  1
2007 Ma L, Teruya-Feldstein J, Weinberg RA. Tumour invasion and metastasis initiated by microRNA-10b in breast cancer. Nature. 449: 682-8. PMID 17898713 DOI: 10.1038/nature06174  1
2007 Liao MJ, Zhang CC, Zhou B, Zimonjic DB, Mani SA, Kaba M, Gifford A, Reinhardt F, Popescu NC, Guo W, Eaton EN, Lodish HF, Weinberg RA. Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity. Cancer Research. 67: 8131-8. PMID 17804725 DOI: 10.1158/0008-5472.CAN-06-4493  1
2007 Ince TA, Richardson AL, Bell GW, Saitoh M, Godar S, Karnoub AE, Iglehart JD, Weinberg RA. Transformation of different human breast epithelial cell types leads to distinct tumor phenotypes. Cancer Cell. 12: 160-70. PMID 17692807 DOI: 10.1016/j.ccr.2007.06.013  1
2007 Mani SA, Yang J, Brooks M, Schwaninger G, Zhou A, Miura N, Kutok JL, Hartwell K, Richardson AL, Weinberg RA. Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers. Proceedings of the National Academy of Sciences of the United States of America. 104: 10069-74. PMID 17537911 DOI: 10.1073/pnas.0703900104  1
2007 Gupta PB, Proia D, Cingoz O, Weremowicz J, Naber SP, Weinberg RA, Kuperwasser C. Systemic stromal effects of estrogen promote the growth of estrogen receptor-negative cancers. Cancer Research. 67: 2062-71. PMID 17332335 DOI: 10.1158/0008-5472.CAN-06-3895  1
2007 Weinberg RA. Determinants of invasion and metastasis Medicina. 67: 3-5.  1
2006 Karnoub AE, Weinberg RA. Chemokine networks and breast cancer metastasis. Breast Disease. 26: 75-85. PMID 17473367  1
2006 Hartwell KA, Muir B, Reinhardt F, Carpenter AE, Sgroi DC, Weinberg RA. The Spemann organizer gene, Goosecoid, promotes tumor metastasis. Proceedings of the National Academy of Sciences of the United States of America. 103: 18969-74. PMID 17142318 DOI: 10.1073/pnas.0608636103  1
2006 Orimo A, Weinberg RA. Stromal fibroblasts in cancer: a novel tumor-promoting cell type. Cell Cycle (Georgetown, Tex.). 5: 1597-601. PMID 16880743  1
2006 Weinberg RA. A lost generation. Cell. 126: 9-10. PMID 16839866 DOI: 10.1016/j.cell.2006.06.022  1
2006 Stewart SA, Weinberg RA. Telomeres: cancer to human aging. Annual Review of Cell and Developmental Biology. 22: 531-57. PMID 16824017 DOI: 10.1146/annurev.cellbio.22.010305.104518  1
2006 Yang J, Mani SA, Weinberg RA. Exploring a new twist on tumor metastasis. Cancer Research. 66: 4549-52. PMID 16651402 DOI: 10.1158/0008-5472.CAN-05-3850  1
2005 Gupta PB, Mani S, Yang J, Hartwell K, Weinberg RA. The evolving portrait of cancer metastasis. Cold Spring Harbor Symposia On Quantitative Biology. 70: 291-7. PMID 16869765 DOI: 10.1101/sqb.2005.70.033  1
2005 Gupta PB, Kuperwasser C, Brunet JP, Ramaswamy S, Kuo WL, Gray JW, Naber SP, Weinberg RA. The melanocyte differentiation program predisposes to metastasis after neoplastic transformation. Nature Genetics. 37: 1047-54. PMID 16142232 DOI: 10.1038/ng1634  1
2005 Kuperwasser C, Dessain S, Bierbaum BE, Garnet D, Sperandio K, Gauvin GP, Naber SP, Weinberg RA, Rosenblatt M. A mouse model of human breast cancer metastasis to human bone. Cancer Research. 65: 6130-8. PMID 16024614 DOI: 10.1158/0008-5472.CAN-04-1408  1
2005 Orimo A, Gupta PB, Sgroi DC, Arenzana-Seisdedos F, Delaunay T, Naeem R, Carey VJ, Richardson AL, Weinberg RA. Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell. 121: 335-48. PMID 15882617 DOI: 10.1016/j.cell.2005.02.034  1
2005 Ben-Porath I, Weinberg RA. The signals and pathways activating cellular senescence. The International Journal of Biochemistry & Cell Biology. 37: 961-76. PMID 15743671 DOI: 10.1016/j.biocel.2004.10.013  1
2004 Dessain SK, Adekar SP, Stevens JB, Carpenter KA, Skorski ML, Barnoski BL, Goldsby RA, Weinberg RA. High efficiency creation of human monoclonal antibody-producing hybridomas. Journal of Immunological Methods. 291: 109-22. PMID 15345310 DOI: 10.1016/j.jim.2004.05.005  1
2004 Rangarajan A, Hong SJ, Gifford A, Weinberg RA. Species- and cell type-specific requirements for cellular transformation. Cancer Cell. 6: 171-83. PMID 15324700 DOI: 10.1016/j.ccr.2004.07.009  1
2004 Yang J, Mani SA, Donaher JL, Ramaswamy S, Itzykson RA, Come C, Savagner P, Gitelman I, Richardson A, Weinberg RA. Twist, a master regulator of morphogenesis, plays an essential role in tumor metastasis. Cell. 117: 927-39. PMID 15210113 DOI: 10.1016/j.cell.2004.06.006  1
2004 Kuperwasser C, Chavarria T, Wu M, Magrane G, Gray JW, Carey L, Richardson A, Weinberg RA. Reconstruction of functionally normal and malignant human breast tissues in mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 4966-71. PMID 15051869 DOI: 10.1073/pnas.0401064101  1
2004 Weinberg RA. Inadvertent cancer research. Cancer Biology & Therapy. 3: 238-9. PMID 15034295  1
2004 Ben-Porath I, Weinberg RA. When cells get stressed: an integrative view of cellular senescence. The Journal of Clinical Investigation. 113: 8-13. PMID 14702100 DOI: 10.1172/JCI20663  1
2003 Rangarajan A, Weinberg RA. Opinion: Comparative biology of mouse versus human cells: modelling human cancer in mice. Nature Reviews. Cancer. 3: 952-9. PMID 14737125 DOI: 10.1038/nrc1235  1
2003 Masutomi K, Yu EY, Khurts S, Ben-Porath I, Currier JL, Metz GB, Brooks MW, Kaneko S, Murakami S, DeCaprio JA, Weinberg RA, Stewart SA, Hahn WC. Telomerase maintains telomere structure in normal human cells. Cell. 114: 241-53. PMID 12887925 DOI: 10.1016/S0092-8674(03)00550-6  1
2003 Stenvers KL, Tursky ML, Harder KW, Kountouri N, Amatayakul-Chantler S, Grail D, Small C, Weinberg RA, Sizeland AM, Zhu HJ. Heart and liver defects and reduced transforming growth factor beta2 sensitivity in transforming growth factor beta type III receptor-deficient embryos. Molecular and Cellular Biology. 23: 4371-85. PMID 12773577 DOI: 10.1128/MCB.23.12.4371-4385.2003  1
2003 Watnick RS, Cheng YN, Rangarajan A, Ince TA, Weinberg RA. Ras modulates Myc activity to repress thrombospondin-1 expression and increase tumor angiogenesis. Cancer Cell. 3: 219-31. PMID 12676581 DOI: 10.1016/S1535-6108(03)00030-8  1
2003 Stewart SA, Ben-Porath I, Carey VJ, O'Connor BF, Hahn WC, Weinberg RA. Erosion of the telomeric single-strand overhang at replicative senescence. Nature Genetics. 33: 492-6. PMID 12652299 DOI: 10.1038/ng1127  1
2003 Stewart SA, Dykxhoorn DM, Palliser D, Mizuno H, Yu EY, An DS, Sabatini DM, Chen IS, Hahn WC, Sharp PA, Weinberg RA, Novina CD. Lentivirus-delivered stable gene silencing by RNAi in primary cells. Rna (New York, N.Y.). 9: 493-501. PMID 12649500 DOI: 10.1261/rna.2192803  1
2002 Jacks T, Weinberg RA. Taking the study of cancer cell survival to a new dimension. Cell. 111: 923-5. PMID 12507419 DOI: 10.1016/S0092-8674(02)01229-1  1
2002 Brisken C, Ayyannan A, Nguyen C, Heineman A, Reinhardt F, Tan J, Dey SK, Dotto GP, Weinberg RA, Jan T. IGF-2 is a mediator of prolactin-induced morphogenesis in the breast. Developmental Cell. 3: 877-87. PMID 12479812 DOI: 10.1016/S1534-5807(02)00365-9  1
2002 Hahn WC, Weinberg RA. Rules for making human tumor cells New England Journal of Medicine. 347: 1593-1603. PMID 12432047 DOI: 10.1056/NEJMra021902  1
2002 Li R, Rasnick D, Duesberg P, Zimonjic DB, Brooks MW, Popescu N, Weinberg RA, Hahn WC. Correspondence re: D. Zimonjic et al., Derivation of human tumor cells in vitro without widespread genomic instability. Cancer Res., 61: 8838-8844, 2001. [1] (multiple letters) Cancer Research. 62: 6345-6349. PMID 12414667  1
2002 Sherley JL, Bernards R, Weinberg RA. Metastasis: Objections to the same-gene model [3] (multiple letters) Nature. 419: 560. PMID 12374949  1
2002 Stewart SA, Hahn WC, O'Connor BF, Banner EN, Lundberg AS, Modha P, Mizuno H, Brooks MW, Fleming M, Zimonjic DB, Popescu NC, Weinberg RA. Telomerase contributes to tumorigenesis by a telomere length-independent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 99: 12606-11. PMID 12193655 DOI: 10.1073/pnas.182407599  1
2002 Bernards R, Weinberg RA. A progression puzzle Nature. 418: 823. PMID 12192390 DOI: 10.1038/418823a  1
2002 Weinberg RA. Cancer biology and therapy: The road ahead Cancer Biology and Therapy. 1: 3. PMID 12170761 DOI: 10.4161/cbt.1.1.29  1
2002 Ince TA, Weinberg RA. Functional genomics and the breast cancer problem Cancer Cell. 1: 15-17. PMID 12086883 DOI: 10.1016/S1535-6108(02)00023-5  1
2002 Lundberg AS, Randell SH, Stewart SA, Elenbaas B, Hartwell KA, Brooks MW, Fleming MD, Olsen JC, Miller SW, Weinberg RA, Hahn WC. Immortalization and transformation of primary human airway epithelial cells by gene transfer. Oncogene. 21: 4577-86. PMID 12085236 DOI: 10.1038/sj.onc.1205550  1
2002 Hahn WC, Weinberg RA. Modelling the molecular circuitry of cancer Nature Reviews Cancer. 2: 331-341. PMID 12044009  1
2002 Hahn WC, Dessain SK, Brooks MW, King JE, Elenbaas B, Sabatini DM, DeCaprio JA, Weinberg RA. Enumeration of the simian virus 40 early region elements necessary for human cell transformation. Molecular and Cellular Biology. 22: 2111-23. PMID 11884599 DOI: 10.1128/MCB.22.7.2111-2123.2002  1
2002 Stewart SA, Weinberg RA. Senescence: does it all happen at the ends? Oncogene. 21: 627-30. PMID 11850788 DOI: 10.1038/sj.onc.1205062  1
2001 Zimonjic D, Brooks MW, Popescu N, Weinberg RA, Hahn WC. Derivation of human tumor cells in vitro without widespread genomic instability Cancer Research. 61: 8838-8844. PMID 11751406  0.32
2001 Vaziri H, Dessain SK, Eaton EN, Imai SI, Frye RA, Pandita TK, Guarente L, Weinberg RA. hSIR2SIRT1 functions as an NAD-dependent p53 deacetylase Cell. 107: 149-159. PMID 11672523 DOI: 10.1016/S0092-8674(01)00527-X  1
2001 Perlman R, Schiemann WP, Brooks MW, Lodish HF, Weinberg RA. TGF-β-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation Nature Cell Biology. 3: 708-714. PMID 11483955 DOI: 10.1038/35087019  1
2001 Planas-Silva MD, Shang Y, Donaher JL, Brown M, Weinberg RA. AIB1 enhances estrogen-dependent induction of cyclin D1 expression Cancer Research. 61: 3858-3862. PMID 11358796  1
2001 Liu X, Sun Y, Weinberg RA, Lodish HF. Ski/Sno and TGF-β signaling Cytokine and Growth Factor Reviews. 12: 1-8. PMID 11312113 DOI: 10.1016/S1359-6101(00)00031-9  1
2001 Weinberg RA. A question of strategy Trends in Biochemical Sciences. 26: 207-208. PMID 11295537 DOI: 10.1016/S0968-0004(01)01823-0  1
2001 Schratt G, Weinhold B, Lundberg AS, Schuck S, Berger J, Schwarz H, Weinberg RA, Rüther U, Nordheim A. Serum response factor is required for immediate-early gene activation yet is dispensable for proliferation of embryonic stem cells. Molecular and Cellular Biology. 21: 2933-43. PMID 11283270 DOI: 10.1128/MCB.21.8.2933-2943.2001  0.32
2001 Elenbaas B, Weinberg RA. Heterotypic signaling between epithelial tumor cells and fibroblasts in carcinoma formation Experimental Cell Research. 264: 169-184. PMID 11237532 DOI: 10.1006/excr.2000.5133  1
2001 Elenbaas B, Spirio L, Koerner F, Fleming MD, Zimonjic DB, Donaher JL, Popescu NC, Hahn WC, Weinberg RA. Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. Genes & Development. 15: 50-65. PMID 11156605 DOI: 10.1101/gad.828901  1
2000 Stewart SA, Weinberg RA. Telomerase and human tumorigenesis Seminars in Cancer Biology. 10: 399-406. PMID 11170862 DOI: 10.1006/scbi.2000.0339  1
2000 Liu X, Sun Y, Ehrlich M, Lu T, Kloog Y, Weinberg RA, Lodish HF, Henis YI. Disruption of TGF-β growth inhibition by oncogenic ras is linked to p27(kip1) mislocalization Oncogene. 19: 5926-5935. PMID 11127824 DOI: 10.1038/sj.onc.1203991  1
2000 Lundberg AS, Hahn WC, Gupta P, Weinberg RA. Genes involved in senescence and immortalization. Current Opinion in Cell Biology. 12: 705-9. PMID 11063935 DOI: 10.1016/S0955-0674(00)00155-1  1
2000 Liu X, Constantinescu SN, Sun Y, Bogan JS, Hirsch D, Weinberg RA, Lodish HF. Generation of mammalian cells stably expressing multiple genes at predetermined levels Analytical Biochemistry. 280: 20-28. PMID 10805516 DOI: 10.1006/abio.2000.4478  1
2000 Lander ES, Weinberg RA. Genomics: journey to the center of biology. Science (New York, N.Y.). 287: 1777-82. PMID 10755930  1
2000 Brisken C, Heineman A, Chavarria T, Elenbaas B, Tan J, Dey SK, McMahon JA, McMahon AP, Weinberg RA. Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling. Genes & Development. 14: 650-4. PMID 10733525  1
2000 Dessain SK, Yu HY, Reddel RR, Beijersbergen RL, Weinberg RA. Methylation of the human telomerase gene CpG island Cancer Research. 60: 537-541. PMID 10676632  1
2000 Dickson MA, Hahn WC, Ino Y, Ronfard V, Wu JY, Weinberg RA, Louis DN, Li FP, Rheinwald JG. Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics. Molecular and Cellular Biology. 20: 1436-47. PMID 10648628 DOI: 10.1128/MCB.20.4.1436-1447.2000  1
2000 Hanahan D, Weinberg RA. The hallmarks of cancer. Cell. 100: 57-70. PMID 10647931 DOI: 10.1016/S0092-8674(00)81683-9  1
1999 Lundberg AS, Weinberg RA. Control of the cell cycle and apoptosis. European Journal of Cancer (Oxford, England : 1990). 35: 1886-94. PMID 10711231 DOI: 10.1016/S0959-8049(99)00292-0  1
1999 Sun Y, Liu X, Eaton EN, Lane WS, Lodish HF, Weinberg RA. Interaction of the Ski oncoprotein with Smad3 regulates TGF-β signaling Molecular Cell. 4: 499-509. PMID 10549282 DOI: 10.1016/S1097-2765(00)80201-4  1
1999 Sun Y, Liu X, Ng-Eaton E, Lodish HF, Weinberg RA. SnoN and Ski protooncoproteins are rapidly degraded in response to transforming growth factor β signaling Proceedings of the National Academy of Sciences of the United States of America. 96: 12442-12447. PMID 10535941 DOI: 10.1073/pnas.96.22.12442  1
1999 Planas-Silva MD, Donaher L, Weinberg RA. Functional activity of ectopically expressed estrogen receptor is not sufficient for estrogen-mediated cyclin D1 expression Cancer Research. 59: 4788-4792. PMID 10519385  1
1999 Hahn WC, Stewart SA, Brooks MW, York SG, Eaton E, Kurachi A, Beijersbergen RL, Knoll JH, Meyerson M, Weinberg RA. Inhibition of telomerase limits the growth of human cancer cells. Nature Medicine. 5: 1164-70. PMID 10502820 DOI: 10.1038/13495  1
1999 Lundberg AS, Weinberg RA. Control of the cell cycle and apoptosis. European Journal of Cancer (Oxford, England : 1990). 35: 531-9. PMID 10492624 DOI: 10.1016/S0959-8049(99)00046-5  1
1999 Hahn WC, Counter CM, Lundberg AS, Beijersbergen RL, Brooks MW, Weinberg RA. Creation of human tumour cells with defined genetic elements. Nature. 400: 464-8. PMID 10440377 DOI: 10.1038/22780  1
1999 Geng Y, Whoriskey W, Park MY, Bronson RT, Medema RH, Li T, Weinberg RA, Sicinski P. Rescue of cyclin D1 deficiency by knockin cyclin E Cell. 97: 767-777. PMID 10380928 DOI: 10.1016/S0092-8674(00)80788-6  1
1999 Brisken C, Kaur S, Chavarria TE, Binart N, Sutherland RL, Weinberg RA, Kelly PA, Ormandy CJ. Prolactin controls mammary gland development via direct and indirect mechanisms Developmental Biology. 210: 96-106. PMID 10364430 DOI: 10.1006/dbio.1999.9271  1
1999 Lees JA, Weinberg RA. Tossing monkey wrenches into the clock: new ways of treating cancer. Proceedings of the National Academy of Sciences of the United States of America. 96: 4221-3. PMID 10200241 DOI: 10.1073/pnas.96.8.4221  1
1998 Counter CM, Hahn WC, Wei W, Caddle SD, Beijersbergen RL, Lansdorp PM, Sedivy JM, Weinberg RA. Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization. Proceedings of the National Academy of Sciences of the United States of America. 95: 14723-8. PMID 9843956 DOI: 10.1073/pnas.95.25.14723  1
1998 Weinberg RA. Bumps on the road to immortality Nature. 396: 23-24. PMID 9817198  1
1998 Robles AI, Rodriguez-Puebla ML, Glick AB, Trempus C, Hansen L, Sicinski P, Tennant RW, Weinberg RA, Yuspa SH, Conti CJ. Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo Genes and Development. 12: 2469-2474. PMID 9716400  1
1998 Kolquist KA, Ellisen LW, Counter CM, Meyerson M, Tan LK, Weinberg RA, Haber DA, Gerald WL. Expression of TERT in early premalignant lesions and a subset of cells in normal tissues. Nature Genetics. 19: 182-6. PMID 9620778 DOI: 10.1038/554  1
1998 Jacks T, Weinberg RA. The expanding role of cell cycle regulators Science. 280: 1035-1036. PMID 9616080 DOI: 10.1126/science.280.5366.1035  1
1998 Brisken C, Park S, Vass T, Lydon JP, O'Malley BW, Weinberg RA. A paracrine role for the epithelial progesterone receptor in mammary gland development Proceedings of the National Academy of Sciences of the United States of America. 95: 5076-5081. PMID 9560231 DOI: 10.1073/pnas.95.9.5076  1
1998 Counter CM, Meyerson M, Eaton EN, Ellisen LW, Caddle SD, Haber DA, Weinberg RA. Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase. Oncogene. 16: 1217-22. PMID 9528864 DOI: 10.1038/sj.onc.1201882  1
1998 Orr-Weaver TL, Weinberg RA. A checkpoint on the road to cancer. Nature. 392: 223-4. PMID 9521314 DOI: 10.1038/32520  1
1998 Lundberg AS, Weinberg RA. Functional inactivation of the retinoblastoma protein requires sequential modification by at least two distinct cyclin-cdk complexes. Molecular and Cellular Biology. 18: 753-61. PMID 9447971  1
1997 Sicinski P, Weinberg RA. A specific role for cyclin D1 in mammary gland development Journal of Mammary Gland Biology and Neoplasia. 2: 335-342. PMID 10935021  1
1997 Leonardo ED, Hinck L, Masu M, Keino-Masu K, Fazeli A, Stoeckli ET, Ackerman SL, Weinberg RA, Tessier-Lavigne M. Guidance of developing axons by netrin-1 and its receptors. Cold Spring Harbor Symposia On Quantitative Biology. 62: 467-78. PMID 9598381  1
1997 Planas-Silva MD, Weinberg RA. The restriction point and control of cell proliferation Current Opinion in Cell Biology. 9: 768-772. PMID 9425340 DOI: 10.1016/S0955-0674(97)80076-2  1
1997 Liu X, Sun Y, Constantinescu SN, Karam E, Weinberg RA, Lodish HF. Transforming growth factorβ-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells Proceedings of the National Academy of Sciences of the United States of America. 94: 10669-10674. PMID 9380693 DOI: 10.1073/pnas.94.20.10669  1
1997 Fazeli A, Steen RG, Dickinson SL, Bautista D, Dietrich WF, Bronson RT, Bresalier RS, Lander ES, Costa J, Weinberg RA. Effects of p53 mutations on apoptosis in mouse intestinal and human colonic adenomas Proceedings of the National Academy of Sciences of the United States of America. 94: 10199-10204. PMID 9294187 DOI: 10.1073/pnas.94.19.10199  1
1997 Meyerson M, Counter CM, Eaton EN, Ellisen LW, Steiner P, Caddle SD, Ziaugra L, Beijersbergen RL, Davidoff MJ, Liu Q, Bacchetti S, Haber DA, Weinberg RA. hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization. Cell. 90: 785-95. PMID 9288757 DOI: 10.1016/S0092-8674(00)80538-3  1
1997 Counter CM, Meyerson M, Eaton EN, Weinberg RA. The catalytic subunit of yeast telomerase. Proceedings of the National Academy of Sciences of the United States of America. 94: 9202-7. PMID 9256460 DOI: 10.1073/pnas.94.17.9202  1
1997 Steiner P, Barnes DM, Harris WH, Weinberg RA. Absence of rearrangements in the tumour susceptibility gene TSG101 in human breast cancer Nature Genetics. 16: 332-333. PMID 9241265  1
1997 Planas-Silva MD, Weinberg RA. Estrogen-dependent cyclin E-cdk2 activation through p21 redistribution Molecular and Cellular Biology. 17: 4059-4069. PMID 9199341  1
1996 Cobrinik D, Lee MH, Hannon G, Mulligan G, Bronson RT, Dyson N, Harlow E, Beach D, Weinberg RA, Jacks T. Shared role of the pRB-related p130 and p107 proteins in limb development. Genes & Development. 10: 1633-44. PMID 8682294  1
1996 Jacks T, Weinberg RA. Cell-cycle control and its watchman. Nature. 381: 643-4. PMID 8649505 DOI: 10.1038/381643a0  1
1996 Herrera RE, Sah VP, Williams BO, Mäkelä TP, Weinberg RA, Jacks T. Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts Molecular and Cellular Biology. 16: 2402-2407. PMID 8628308  1
1994 Williams BO, Schmitt EM, Remington L, Bronson RT, Albert DM, Weinberg RA, Jacks T. Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences Embo Journal. 13: 4251-4259. PMID 7925270  1
1994 Jacks T, Remington L, Williams BO, Schmitt EM, Halachmi S, Bronson RT, Weinberg RA. Tumor spectrum analysis in p53-mutant mice Current Biology. 4: 1-7. PMID 7922305 DOI: 10.1016/S0960-9822(00)00002-6  1
1994 Jacks T, Shih TS, Schmitt EM, Bronson RT, Bernards A, Weinberg RA. Tumour predisposition in mice heterozygous for a targeted mutation in Nf1 Nature Genetics. 7: 353-361. PMID 7920653 DOI: 10.1038/ng0794-353  1
1994 Hatakeyama M, Herrera RA, Makela T, Dowdy SF, Jacks T, Weinberg RA. The cancer cell and the cell cycle clock. Cold Spring Harbor Symposia On Quantitative Biology. 59: 1-10. PMID 7587058  1
1993 Cobrinik D, Whyte P, Peeper DS, Jacks T, Weinberg RA. Cell cycle-specific association of E2F with the p130 E1A-binding protein. Genes & Development. 7: 2392-404. PMID 8253385  1
1992 Jacks T, Fazeli A, Schmitt EM, Bronson RT, Goodell MA, Weinberg RA. Effects of an Rb mutation in the mouse Nature. 359: 295-300. PMID 1406933  1
1989 Yarden Y, Weinberg RA. Experimental approaches to hypothetical hormones: detection of a candidate ligand of the neu protooncogene. Proceedings of the National Academy of Sciences of the United States of America. 86: 3179-83. PMID 2470093  1
1988 Bargmann CI, Weinberg RA. Oncogenic activation of the neu-encoded receptor protein by point mutation and deletion. The Embo Journal. 7: 2043-52. PMID 2901345  1
1988 Bargmann CI, Weinberg RA. Increased tyrosine kinase activity associated with the protein encoded by the activated neu oncogene. Proceedings of the National Academy of Sciences of the United States of America. 85: 5394-8. PMID 2899890  1
1986 Bargmann CI, Hung MC, Weinberg RA. The neu oncogene encodes an epidermal growth factor receptor-related protein. Nature. 319: 226-30. PMID 3945311 DOI: 10.1038/319226a0  1
1986 Land H, Chen AC, Morgenstern JP, Parada LF, Weinberg RA. Behavior of myc and ras oncogenes in transformation of rat embryo fibroblasts. Molecular and Cellular Biology. 6: 1917-25. PMID 3785184  0.76
1986 Gilman MZ, Wilson RN, Weinberg RA. Multiple protein-binding sites in the 5'-flanking region regulate c-fos expression. Molecular and Cellular Biology. 6: 4305-16. PMID 3025651  0.36
1986 Stern DF, Roberts AB, Roche NS, Sporn MB, Weinberg RA. Differential responsiveness of myc- and ras-transfected cells to growth factors: Selective stimulation of myc-transfected cells by epidermal growth factor Molecular and Cellular Biology. 6: 870-877. PMID 3022135  0.56
1986 Hung MC, Schechter AL, Chevray PYM, Stern DF, Weinberg RA. Molecular cloning of the neu gene: Absence of gross structural alteration in oncogenic alleles Proceedings of the National Academy of Sciences of the United States of America. 83: 261-264. PMID 3001730  0.56
1986 Friend SH, Bernards R, Rogelj S, Weinberg RA, Rapaport JM, Albert DM, Dryja TP. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma Nature. 323: 643-646. PMID 2877398 DOI: 10.1038/323643a0  0.56
1986 Bargmann CI, Hung MC, Weinberg RA. Multiple independent activations of the neu oncogene by a point mutation altering the transmembrane domain of p185. Cell. 45: 649-57. PMID 2871941 DOI: 10.1016/0092-8674(86)90779-8  1
1986 Dotto GP, Gilman MZ, Maruyama M, Weinberg RA. c-myc and c-fos expression in differentiating mouse primary keratinocytes. The Embo Journal. 5: 2853-7. PMID 2431900  0.56
1985 Dotto GP, Parada LF, Weinberg RA. Specific growth response of ras-transformed embryo fibroblasts to tumour promoters. Nature. 318: 472-5. PMID 4069218  0.76
1985 Parada LF, Land H, Chen A, Morganstern J, Weinberg RA. Cooperation between cellular oncogenes in the transformation of primary rat embryo fibroblasts. Progress in Medical Virology. Fortschritte Der Medizinischen Virusforschung. ProgrèS En Virologie MéDicale. 32: 115-28. PMID 4023262  0.76
1985 Schechter AL, Hung MC, Vaidyanathan L, Weinberg RA, Yang-Feng TL, Francke U, Ullrich A, Coussens L. The neu gene: An erbB-homologous gene distinct from and unlinked to the gene encoding the EGF receptor Science. 229: 976-978. PMID 2992090  0.56
1985 Tabin CJ, Weinberg RA. Analysis of viral and somatic activations of the cHa-ras gene. Journal of Virology. 53: 260-5. PMID 2981345  1
1985 Drebin JA, Link VC, Stern DF, Weinberg RA, Greene MI. Down-modulation of an oncogene protein product and reversion of the transformed phenotype by monoclonal antibodies Cell. 41: 695-706. PMID 2860972 DOI: 10.1016/S0092-8674(85)80050-7  0.56
1984 Drebin JA, Stern DF, Link VC, Weinberg RA, Greene MI. Monoclonal antibodies identify a cell-surface antigen associated with an activated cellular oncogene Nature. 312: 545-548. PMID 6504162 DOI: 10.1038/312545a0  0.56
1984 Parada LF, Land H, Weinberg RA, Wolf D, Rotter V. Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation. Nature. 312: 649-51. PMID 6390217 DOI: 10.1038/312649a0  1
1984 Schechter AL, Stern DF, Vaidyanathan L, Decker SJ, Drebin JA, Greene MI, Weinberg RA. The neu oncogene: An erb-B-related gene encoding a 185,000-M(r) tumour antigen Nature. 312: 513-516. PMID 6095109 DOI: 10.1038/312513a0  0.56
1984 McCoy MS, Bargmann CI, Weinberg RA. Human colon carcinoma Ki-ras2 oncogene and its corresponding proto-oncogene. Molecular and Cellular Biology. 4: 1577-82. PMID 6092920  1
1984 Lenoir GM, Land H, Parada LF, Cunningham JM, Weinberg RA. Activated oncogenes in Burkitt's lymphoma. Current Topics in Microbiology and Immunology. 113: 6-14. PMID 6090072  0.76
1983 Sakaguchi AY, Naylor SL, Shows TB, Toole JJ, McCoy M, Weinberg RA. Human c-Ki-ras2 proto-oncogene on chromosome 12 Science. 219: 1081-1083. PMID 6823569  0.56
1983 Murray MJ, Cunningham JM, Parada LF, Dautry F, Lebowitz P, Weinberg RA. The HL-60 transforming sequence: a ras oncogene coexisting with altered myc genes in hematopoietic tumors. Cell. 33: 749-57. PMID 6683594  0.76
1983 Parada LF, Shih C, Murray M, Weinberg RA. The oncogene of a human bladder carcinoma. Progress in Nucleic Acid Research and Molecular Biology. 29: 269-72. PMID 6665172  0.76
1983 Land H, Parada LF, Weinberg RA. Cellular oncogenes and multistep carcinogenesis. Science (New York, N.Y.). 222: 771-8. PMID 6356358  0.76
1983 Land H, Parada LF, Weinberg RA. Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature. 304: 596-602. PMID 6308472  0.76
1983 McCoy MS, Toole JJ, Cunningham JM, Chang EH, Lowy DR, Weinberg RA. Characterization of a human colon/lung carcinoma oncogene. Nature. 302: 79-81. PMID 6298638 DOI: 10.1038/302079a0  0.56
1983 de Martinville B, Giacalone J, Shih C, Weinberg RA, Francke U. Oncogene from human EJ bladder carcinoma is located on the short arm of chromosome 11 Science. 219: 498-501. PMID 6297001 DOI: 10.1126/science.6297001  0.56
1983 Parada LF, Weinberg RA. Presence of a Kirsten murine sarcoma virus ras oncogene in cells transformed by 3-methylcholanthrene. Molecular and Cellular Biology. 3: 2298-301. PMID 6197628  0.76
1982 Tabin CJ, Bradley SM, Bargmann CI, Weinberg RA, Papageorge AG, Scolnick EM, Dhar R, Lowy DR, Chang EH. Mechanism of activation of a human oncogene. Nature. 300: 143-9. PMID 6290897 DOI: 10.1038/300143a0  0.56
1982 Parada LF, Tabin CJ, Shih C, Weinberg RA. Human EJ bladder carcinoma oncogene is homologue of Harvey sarcoma virus ras gene. Nature. 297: 474-8. PMID 6283357 DOI: 10.1038/297474a0  1
1982 Tabin CJ, Hoffmann JW, Goff SP, Weinberg RA. Adaptation of a retrovirus as a eucaryotic vector transmitting the herpes simplex virus thymidine kinase gene. Molecular and Cellular Biology. 2: 426-36. PMID 6180306  1
1981 Coffin JM, Varmus HE, Bishop JM, Essex M, Hardy WD, Martin GS, Rosenberg NE, Scolnick EM, Weinberg RA, Vogt PK. Proposal for naming host cell-derived inserts in retrovirus genomes. Journal of Virology. 40: 953-7. PMID 7321107  0.56
1981 Goldfarb MP, Weinberg RA. Generation of novel, biologically active Harvey sarcoma viruses via apparent illegitimate recombination. Journal of Virology. 38: 136-50. PMID 7241647  1
1981 Goldfarb MP, Weinberg RA. Structure of the provirus within NIH 3T3 cells transfected with Harvey sarcoma virus DNA. Journal of Virology. 38: 125-35. PMID 7241646  1
1980 Donoghue DJ, Goldfarb MP, Sharp PA, Weinberg RA. Organization of murine sarcoma virus genomes. Cold Spring Harbor Symposia On Quantitative Biology. 44: 721-6. PMID 6253206  1
1979 Steffen D, Andersson P, Goldfarb M, Weinberg RA. Integration and possible transduction by retroviruses. Cold Spring Harbor Symposia On Quantitative Biology. 43: 875-9. PMID 290450  1
1979 Goldfarb MP, Weinberg RA. Physical map of biologically active Harvey sarcoma virus unintegrated linear DNA. Journal of Virology. 32: 30-9. PMID 232180  1
1979 Shih C, Shilo BZ, Goldfarb MP, Dannenberg A, Weinberg RA. Passage of phenotypes of chemically transformed cells via transfection of DNA and chromatin. Proceedings of the National Academy of Sciences of the United States of America. 76: 5714-8. PMID 230490 DOI: 10.1073/pnas.76.11.5714  0.92
1979 Andersson P, Goldfarb MP, Weinberg RA. A defined subgenomic fragment of in vitro synthesized Moloney sarcoma virus DNA can induce cell transformation upon transfection. Cell. 16: 63-75. PMID 84715 DOI: 10.1016/0092-8674(79)90188-0  1
1977 Rothenberg E, Smotkin D, Baltimore D, Weinberg RA. In vitro synthesis of infectious DNA of murine leukaemia virus. Nature. 269: 122-6. PMID 71657  0.76
1975 Paskind MP, Weinberg RA, Baltimore D. Dependence of Moloney murine leukemia virus production on cell growth. Virology. 67: 242-8. PMID 1172324  0.76
1973 Leibowitz RD, Weinberg RA, Penman S. Unusual metabolism of 5 S RNA in HeLa cells. Journal of Molecular Biology. 73: 139-44. PMID 4690307  0.28
1972 Weinberg RA, Warnaar SO, Winocour E. Isolation and characterization of simian virus 40 ribonucleic acid. Journal of Virology. 10: 193-201. PMID 4342237  1
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