Brandon F. Keele, Ph.D. - Publications

Affiliations: 
2003 Brigham Young University, Provo, UT, United States 
Area:
Microbiology Biology, Molecular Biology, Pathology, Immunology

123 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Raehtz KD, Barrenäs F, Xu C, Busman-Sahay K, Valentine A, Law L, Ma D, Policicchio BB, Wijewardana V, Brocca-Cofano E, Trichel A, Gale M, Keele BF, Estes JD, Apetrei C, et al. African green monkeys avoid SIV disease progression by preventing intestinal dysfunction and maintaining mucosal barrier integrity. Plos Pathogens. 16: e1008333. PMID 32119719 DOI: 10.1371/journal.ppat.1008333  0.6
2019 Deleage C, Immonen TT, Fennessey CM, Reynaldi A, Reid C, Newman L, Lipkey L, Schlub TE, Camus C, O'Brien S, Smedley J, Conway JM, Del Prete GQ, Davenport MP, Lifson JD, ... ... Keele BF, et al. Defining early SIV replication and dissemination dynamics following vaginal transmission. Science Advances. 5: eaav7116. PMID 31149634 DOI: 10.1126/sciadv.aav7116  0.6
2018 Hensley-McBain T, Berard AR, Manuzak JA, Miller CJ, Zevin AS, Polacino P, Gile J, Agricola B, Cameron M, Hu SL, Estes JD, Reeves RK, Smedley J, Keele BF, Burgener AD, et al. Intestinal damage precedes mucosal immune dysfunction in SIV infection. Mucosal Immunology. PMID 29907866 DOI: 10.1038/s41385-018-0032-5  0.6
2017 Del Prete GQ, Keele BF, Fode J, Thumar K, Swanstrom AE, Rodriguez A, Raymond A, Estes JD, LaBranche CC, Montefiori DC, KewalRamani VN, Lifson JD, Bieniasz PD, Hatziioannou T. A single gp120 residue can affect HIV-1 tropism in macaques. Plos Pathogens. 13: e1006572. PMID 28945790 DOI: 10.1371/journal.ppat.1006572  0.6
2017 Hansen SG, Piatak M, Ventura AB, Hughes CM, Gilbride RM, Ford JC, Oswald K, Shoemaker R, Li Y, Lewis MS, Gilliam AN, Xu G, Whizin N, Burwitz BJ, Planer SL, ... ... Keele BF, et al. Addendum: Immune clearance of highly pathogenic SIV infection. Nature. PMID 28636599 DOI: 10.1038/nature22984  0.6
2017 Fennessey CM, Pinkevych M, Immonen TT, Reynaldi A, Venturi V, Nadella P, Reid C, Newman L, Lipkey L, Oswald K, Bosche WJ, Trivett MT, Ohlen C, Ott DE, Estes JD, ... ... Keele BF, et al. Genetically-barcoded SIV facilitates enumeration of rebound variants and estimation of reactivation rates in nonhuman primates following interruption of suppressive antiretroviral therapy. Plos Pathogens. 13: e1006359. PMID 28472156 DOI: 10.1371/journal.ppat.1006359  0.6
2016 Thompson M, Heath SL, Sweeton B, Williams K, Cunningham P, Keele BF, Sen S, Palmer BE, Chomont N, Xu Y, Basu R, Hellerstein MS, Kwa S, Robinson HL. DNA/MVA Vaccination of HIV-1 Infected Participants with Viral Suppression on Antiretroviral Therapy, followed by Treatment Interruption: Elicitation of Immune Responses without Control of Re-Emergent Virus. Plos One. 11: e0163164. PMID 27711228 DOI: 10.1371/journal.pone.0163164  0.6
2016 Panico M, Bouché L, Binet D, O'Connor MJ, Rahman D, Pang PC, Canis K, North SJ, Desrosiers RC, Chertova E, Keele BF, Bess JW, Lifson JD, Haslam SM, Dell A, et al. Mapping the complete glycoproteome of virion-derived HIV-1 gp120 provides insights into broadly neutralizing antibody binding. Scientific Reports. 6: 32956. PMID 27604319 DOI: 10.1038/srep32956  0.6
2016 Del Prete GQ, Lifson JD, Keele BF. Nonhuman primate models for the evaluation of HIV-1 preventive vaccine strategies: model parameter considerations and consequences. Current Opinion in Hiv and Aids. PMID 27559710 DOI: 10.1097/COH.0000000000000311  0.6
2016 Lopker MJ, Del Prete GQ, Estes JD, Li H, Reid C, Newman L, Lipkey L, Camus C, Easlick JL, Wang S, Decker JM, Bar KJ, Learn G, Pal R, Weiss DE, ... ... Keele BF, et al. Derivation and characterization of pathogenic transmitted/founder molecular clones from SIVsmE660 and SIVmac251 following mucosal infection. Journal of Virology. PMID 27412591 DOI: 10.1128/JVI.00718-16  0.6
2016 Yuan Z, Kang G, Ma F, Lu W, Fan W, Fennessey CM, Keele BF, Li Q. Recapitulating Cross-Species Transmission of SIVcpz to Humans Using Humanized-BLT Mice. Journal of Virology. PMID 27307566 DOI: 10.1128/JVI.00860-16  0.6
2016 Calascibetta F, Micci L, Carnathan D, Lawson B, Vanderford TH, Bosinger SE, Easley K, Chahroudi A, Mackel J, Keele BF, Long S, Lifson J, Paiardini M, Silvestri G. Antiretroviral therapy in SIV-infected sooty mangabeys: implications for AIDS pathogenesis. Journal of Virology. PMID 27279614 DOI: 10.1128/JVI.00598-16  0.6
2016 Li H, Wang S, Kong R, Ding W, Lee FH, Parker Z, Kim E, Learn GH, Hahn P, Policicchio B, Brocca-Cofano E, Deleage C, Hao X, Chuang GY, Gorman J, ... ... Keele BF, et al. Envelope residue 375 substitutions in simian-human immunodeficiency viruses enhance CD4 binding and replication in rhesus macaques. Proceedings of the National Academy of Sciences of the United States of America. PMID 27247400 DOI: 10.1073/pnas.1606636113  0.6
2016 Vaccari M, Gordon SN, Fourati S, Schifanella L, Liyanage NP, Cameron M, Keele BF, Shen X, Tomaras GD, Billings E, Rao M, Chung AW, Dowell KG, Bailey-Kellogg C, Brown EP, et al. Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition. Nature Medicine. 22: 762-70. PMID 27239761 DOI: 10.1038/nm.4105  0.6
2016 Delviks-Frankenberry KA, Nikolaitchik OA, Burdick RC, Gorelick RJ, Keele BF, Hu WS, Pathak VK. Minimal Contribution of APOBEC3-Induced G-to-A Hypermutation to HIV-1 Recombination and Genetic Variation. Plos Pathogens. 12: e1005646. PMID 27186986 DOI: 10.1371/journal.ppat.1005646  0.6
2016 Apps R, Del Prete GQ, Chatterjee P, Lara A, Brumme ZL, Brockman MA, Neil S, Pickering S, Schneider DK, Piechocka-Trocha A, Walker BD, Thomas R, Shaw GM, Hahn BH, Keele BF, et al. HIV-1 Vpu Mediates HLA-C Downregulation. Cell Host & Microbe. 19: 686-95. PMID 27173934 DOI: 10.1016/j.chom.2016.04.005  0.6
2016 Simonetti FR, Sobolewski MD, Fyne E, Shao W, Spindler J, Hattori J, Anderson EM, Watters SA, Hill S, Wu X, Wells D, Su L, Luke BT, Halvas EK, Besson G, ... ... Keele BF, et al. Clonally expanded CD4+ T cells can produce infectious HIV-1 in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 26858442 DOI: 10.1073/pnas.1522675113  0.6
2015 Del Prete GQ, Oswald K, Lara A, Shoemaker R, Smedley J, Macallister R, Coalter V, Wiles A, Wiles R, Li Y, Fast R, Kiser R, Lu B, Zheng J, Alvord WG, ... ... Keele BF, et al. Elevated plasma viral loads in romidepsin treated SIV-infected rhesus macaques on suppressive combination antiretroviral therapy. Antimicrobial Agents and Chemotherapy. PMID 26711758 DOI: 10.1128/AAC.02625-15  0.6
2015 Kearney MF, Wiegand A, Shao W, Coffin JM, Mellors JW, Lederman M, Gandhi RT, Keele BF, Li JZ. Origin of Rebound Plasma HIV Includes Cells with Identical Proviruses that are Transcriptionally Active Before Stopping Antiretroviral Therapy. Journal of Virology. PMID 26581989 DOI: 10.1128/JVI.02139-15  0.6
2015 Lee FH, Mason R, Welles H, Learn GH, Keele BF, Roederer M, Bar KJ. Breakthrough Virus Neutralization Resistance as a Correlate of Protection in a Nonhuman Primate Heterologous Simian Immunodeficiency Virus Vaccine Challenge Study. Journal of Virology. 89: 12388-400. PMID 26423953 DOI: 10.1128/JVI.01531-15  0.6
2015 Hao XP, Lucero CM, Turkbey B, Bernardo ML, Morcock DR, Deleage C, Trubey CM, Smedley J, Klatt NR, Giavedoni LD, Kristoff J, Xu A, Del Prete GQ, Keele BF, Rao SS, et al. Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection. Nature Communications. 6: 8020. PMID 26282376 DOI: 10.1038/ncomms9020  0.6
2015 Breed MW, Elser SE, Torben W, Jordan AP, Aye PP, Midkiff C, Schiro F, Sugimoto C, Alvarez-Hernandez X, Blair RV, Somasunderam A, Utay NS, Kuroda MJ, Pahar B, Wiseman RW, ... ... Keele BF, et al. Elite Control, Gut CD4 T Cell Sparing, and Enhanced Mucosal T Cell Responses in Macaca nemestrina Infected by a Simian Immunodeficiency Virus Lacking a gp41 Trafficking Motif. Journal of Virology. 89: 10156-75. PMID 26223646 DOI: 10.1128/JVI.01134-15  0.6
2015 Yamamoto T, Lynch RM, Gautam R, Matus-Nicodemos R, Schmidt SD, Boswell KL, Darko S, Wong P, Sheng Z, Petrovas C, McDermott AB, Seder RA, Keele BF, Shapiro L, Douek DC, et al. Quality and quantity of TFH cells are critical for broad antibody development in SHIVAD8 infection. Science Translational Medicine. 7: 298ra120. PMID 26223303 DOI: 10.1126/scitranslmed.aab3964  0.6
2015 Prete GQ, Smedley J, Macallister R, Jones GS, Li B, Hattersley J, Zheng J, Piatak M, Keele BF, Hesselgesser J, Geleziunas R, Lifson JD. Comparative Evaluation of Coformulated Injectable Combination Antiretroviral Therapy Regimens in Simian Immunodeficiency Virus-Infected Rhesus Macaques. Aids Research and Human Retroviruses. PMID 26150024 DOI: 10.1089/AID.2015.0130  0.6
2015 Fennessey CM, Reid C, Lipkey L, Newman L, Oswald K, Piatak M, Roser JD, Chertova E, Smedley J, Gregory Alvord W, Del Prete GQ, Estes JD, Lifson JD, Keele BF. Generation and characterization of a SIVmac239 clone corrected at four suboptimal nucleotides. Retrovirology. 12: 49. PMID 26076651 DOI: 10.1186/s12977-015-0175-3  0.6
2015 Sankineni S, Smedley J, Bernardo M, Brown AM, Johnson L, Muller B, Griffiths GL, Kobayashi H, Rais-Bahrami S, Pinto PA, Wood BJ, Keele B, Choyke PL, Turkbey B. Ferumoxytol as an intraprostatic MR contrast agent for lymph node mapping of the prostate: a feasibility study in non-human primates. Acta Radiologica (Stockholm, Sweden : 1987). PMID 26013022 DOI: 10.1177/0284185115586023  0.6
2015 Francica JR, Sheng Z, Zhang Z, Nishimura Y, Shingai M, Ramesh A, Keele BF, Schmidt SD, Flynn BJ, Darko S, Lynch RM, Yamamoto T, Matus-Nicodemos R, Wolinsky D, et al. Analysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunization. Nature Communications. 6: 6565. PMID 25858157 DOI: 10.1038/ncomms7565  0.6
2015 Rothenberger MK, Keele BF, Wietgrefe SW, Fletcher CV, Beilman GJ, Chipman JG, Khoruts A, Estes JD, Anderson J, Callisto SP, Schmidt TE, Thorkelson A, Reilly C, Perkey K, Reimann TG, et al. Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption. Proceedings of the National Academy of Sciences of the United States of America. 112: E1126-34. PMID 25713386 DOI: 10.1073/pnas.1414926112  0.6
2015 Hao XP, Lucero CM, Turkbey B, Bernardo ML, Morcock DR, Deleage C, Trubey CM, Smedley J, Klatt NR, Giavedoni LD, Kristoff J, Xu A, Del Prete GQ, Keele BF, Rao SS, et al. Experimental colitis in SIV-uninfected rhesus macaques recapitulates important features of pathogenic SIV infection Nature Communications. 6. DOI: 10.1038/ncomms9020  0.6
2015 Nikolaitchik O, Keele B, Gorelick R, Alvord WG, Mazurov D, Pathak VK, Hu WS. High recombination potential of subtype A HIV-1 Virology. 484: 334-340. DOI: 10.1016/j.virol.2015.06.025  0.6
2014 Li H, Richert-Spuhler LE, Evans TI, Gillis J, Connole M, Estes JD, Keele BF, Klatt NR, Reeves RK. Hypercytotoxicity and rapid loss of NKp44+ innate lymphoid cells during acute SIV infection. Plos Pathogens. 10: e1004551. PMID 25503264 DOI: 10.1371/journal.ppat.1004551  0.6
2014 Gordon SN, Doster MN, Kines RC, Keele BF, Brocca-Cofano E, Guan Y, Pegu P, Liyanage NP, Vaccari M, Cuburu N, Buck CB, Ferrari G, Montefiori D, Piatak M, Lifson JD, et al. Antibody to the gp120 V1/V2 loops and CD4+ and CD8+ T cell responses in protection from SIVmac251 vaginal acquisition and persistent viremia. Journal of Immunology (Baltimore, Md. : 1950). 193: 6172-83. PMID 25398324 DOI: 10.4049/jimmunol.1401504  0.6
2014 Reed PE, Mulangu S, Cameron KN, Ondzie AU, Joly D, Bermejo M, Rouquet P, Fabozzi G, Bailey M, Shen Z, Keele BF, Hahn B, Karesh WB, Sullivan NJ. A new approach for monitoring ebolavirus in wild great apes. Plos Neglected Tropical Diseases. 8: e3143. PMID 25232832 DOI: 10.1371/journal.pntd.0003143  0.6
2014 Del Prete GQ, Ailers B, Moldt B, Keele BF, Estes JD, Rodriguez A, Sampias M, Oswald K, Fast R, Trubey CM, Chertova E, Smedley J, LaBranche CC, Montefiori DC, Burton DR, et al. Selection of unadapted, pathogenic SHIVs encoding newly transmitted HIV-1 envelope proteins. Cell Host & Microbe. 16: 412-8. PMID 25211081 DOI: 10.1016/j.chom.2014.08.003  0.6
2014 Matsuda K, Dang Q, Brown CR, Keele BF, Wu F, Ourmanov I, Goeken R, Whitted S, Riddick NE, Buckler-White A, Hirsch VM. Characterization of simian immunodeficiency virus (SIV) that induces SIV encephalitis in rhesus macaques with high frequency: role of TRIM5 and major histocompatibility complex genotypes and early entry to the brain. Journal of Virology. 88: 13201-11. PMID 25187546 DOI: 10.1128/JVI.01996-14  0.6
2014 Del Prete GQ, Shoemaker R, Oswald K, Lara A, Trubey CM, Fast R, Schneider DK, Kiser R, Coalter V, Wiles A, Wiles R, Freemire B, Keele BF, Estes JD, Quiñones OA, et al. Effect of suberoylanilide hydroxamic acid (SAHA) administration on the residual virus pool in a model of combination antiretroviral therapy-mediated suppression in SIVmac239-infected indian rhesus macaques. Antimicrobial Agents and Chemotherapy. 58: 6790-806. PMID 25182644 DOI: 10.1128/AAC.03746-14  0.6
2014 Sandler NG, Bosinger SE, Estes JD, Zhu RT, Tharp GK, Boritz E, Levin D, Wijeyesinghe S, Makamdop KN, del Prete GQ, Hill BJ, Timmer JK, Reiss E, Yarden G, Darko S, ... ... Keele BF, et al. Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression. Nature. 511: 601-5. PMID 25043006 DOI: 10.1038/nature13554  0.6
2014 Hatziioannou T, Del Prete GQ, Keele BF, Estes JD, McNatt MW, Bitzegeio J, Raymond A, Rodriguez A, Schmidt F, Mac Trubey C, Smedley J, Piatak M, KewalRamani VN, Lifson JD, Bieniasz PD. HIV-1-induced AIDS in monkeys. Science (New York, N.Y.). 344: 1401-5. PMID 24948736 DOI: 10.1126/science.1250761  0.6
2014 Sui Y, Hogg A, Wang Y, Frey B, Yu H, Xia Z, Venzon D, McKinnon K, Smedley J, Gathuka M, Klinman D, Keele BF, Langermann S, Liu L, Franchini G, et al. Vaccine-induced myeloid cell population dampens protective immunity to SIV. The Journal of Clinical Investigation. 124: 2538-49. PMID 24837435 DOI: 10.1172/JCI73518  0.6
2014 Del Prete GQ, Park H, Fennessey CM, Reid C, Lipkey L, Newman L, Oswald K, Kahl C, Piatak M, Quiñones OA, Alvord WG, Smedley J, Estes JD, Lifson JD, Picker LJ, ... Keele BF, et al. Molecularly tagged simian immunodeficiency virus SIVmac239 synthetic swarm for tracking independent infection events. Journal of Virology. 88: 8077-90. PMID 24807714 DOI: 10.1128/JVI.01026-14  0.6
2014 Mandell DT, Kristoff J, Gaufin T, Gautam R, Ma D, Sandler N, Haret-Richter G, Xu C, Aamer H, Dufour J, Trichel A, Douek DC, Keele BF, Apetrei C, Pandrea I. Pathogenic features associated with increased virulence upon Simian immunodeficiency virus cross-species transmission from natural hosts. Journal of Virology. 88: 6778-92. PMID 24696477 DOI: 10.1128/JVI.03785-13  0.6
2014 Smedley J, Turkbey B, Bernardo ML, Del Prete GQ, Estes JD, Griffiths GL, Kobayashi H, Choyke PL, Lifson JD, Keele BF. Tracking the luminal exposure and lymphatic drainage pathways of intravaginal and intrarectal inocula used in nonhuman primate models of HIV transmission. Plos One. 9: e92830. PMID 24667371 DOI: 10.1371/journal.pone.0092830  0.6
2014 Hsu M, Keele BF, Aravantinou M, Krawczyk N, Seidor S, Abraham CJ, Zhang S, Rodriguez A, Kizima L, Derby N, Jean-Pierre N, Mizenina O, Gettie A, Grasperge B, Blanchard J, et al. Exposure to MIV-150 from a high-dose intravaginal ring results in limited emergence of drug resistance mutations in SHIV-RT infected rhesus macaques. Plos One. 9: e89300. PMID 24586674 DOI: 10.1371/journal.pone.0089300  0.6
2014 Roederer M, Keele BF, Schmidt SD, Mason RD, Welles HC, Fischer W, Labranche C, Foulds KE, Louder MK, Yang ZY, Todd JP, Buzby AP, Mach LV, Shen L, Seaton KE, et al. Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV. Nature. 505: 502-8. PMID 24352234 DOI: 10.1038/nature12893  0.6
2014 Van Rompay KK, Hunter Z, Jayashankar K, Peabody J, Montefiori D, LaBranche CC, Keele BF, Jensen K, Abel K, Chackerian B. A vaccine against CCR5 protects a subset of macaques upon intravaginal challenge with simian immunodeficiency virus SIVmac251. Journal of Virology. 88: 2011-24. PMID 24307581 DOI: 10.1128/JVI.02447-13  0.6
2014 Lonsdorf E, Travis D, Ssuna R, Lantz E, Wilson M, Gamble K, Terio K, Leendertz F, Ehlers B, Keele B, Hahn B, Gillespie T, Pond J, Raphael J, Collins A. Field immobilization for treatment of an unknown illness in a wild chimpanzee (Pan troglodytes schweinfurthii) at Gombe National Park, Tanzania: findings, challenges, and lessons learned. Primates; Journal of Primatology. 55: 89-99. PMID 23872909 DOI: 10.1007/s10329-013-0372-4  0.6
2013 Breed MW, Jordan AP, Aye PP, Sugimoto C, Alvarez X, Kuroda MJ, Pahar B, Keele BF, Hoxie JA, Lackner AA. A single amino acid mutation in the envelope cytoplasmic tail restores the ability of an attenuated simian immunodeficiency virus mutant to deplete mucosal CD4+ T cells. Journal of Virology. 87: 13048-52. PMID 24027336 DOI: 10.1128/JVI.02126-13  0.6
2013 Hansen SG, Piatak M, Ventura AB, Hughes CM, Gilbride RM, Ford JC, Oswald K, Shoemaker R, Li Y, Lewis MS, Gilliam AN, Xu G, Whizin N, Burwitz BJ, Planer SL, ... ... Keele BF, et al. Immune clearance of highly pathogenic SIV infection. Nature. 502: 100-4. PMID 24025770 DOI: 10.1038/nature12519  0.6
2013 Fennessey CM, Keele BF. Using nonhuman primates to model HIV transmission. Current Opinion in Hiv and Aids. 8: 280-7. PMID 23666391 DOI: 10.1097/COH.0b013e328361cfff  0.6
2013 Sundararaman SA, Liu W, Keele BF, Learn GH, Bittinger K, Mouacha F, Ahuka-Mundeke S, Manske M, Sherrill-Mix S, Li Y, Malenke JA, Delaporte E, Laurent C, Mpoudi Ngole E, Kwiatkowski DP, et al. Plasmodium falciparum-like parasites infecting wild apes in southern Cameroon do not represent a recurrent source of human malaria. Proceedings of the National Academy of Sciences of the United States of America. 110: 7020-5. PMID 23569255 DOI: 10.1073/pnas.1305201110  0.6
2013 Lopker M, Easlick J, Sterrett S, Decker JM, Barbian H, Learn G, Keele BF, Robinson JE, Li H, Hahn BH, Shaw GM, Bar KJ. Heterogeneity in neutralization sensitivities of viruses comprising the simian immunodeficiency virus SIVsmE660 isolate and vaccine challenge stock. Journal of Virology. 87: 5477-92. PMID 23468494 DOI: 10.1128/JVI.03419-12  0.6
2013 Del Prete GQ, Scarlotta M, Newman L, Reid C, Parodi LM, Roser JD, Oswald K, Marx PA, Miller CJ, Desrosiers RC, Barouch DH, Pal R, Piatak M, Chertova E, Giavedoni LD, ... ... Keele BF, et al. Comparative characterization of transfection- and infection-derived simian immunodeficiency virus challenge stocks for in vivo nonhuman primate studies. Journal of Virology. 87: 4584-95. PMID 23408608 DOI: 10.1128/JVI.03507-12  0.6
2013 Patel V, Jalah R, Kulkarni V, Valentin A, Rosati M, Alicea C, von Gegerfelt A, Huang W, Guan Y, Keele BF, Bess JW, Piatak M, Lifson JD, Williams WT, Shen X, et al. DNA and virus particle vaccination protects against acquisition and confers control of viremia upon heterologous simian immunodeficiency virus challenge. Proceedings of the National Academy of Sciences of the United States of America. 110: 2975-80. PMID 23359688 DOI: 10.1073/pnas.1215393110  0.6
2013 Vaccari M, Keele BF, Bosinger SE, Doster MN, Ma ZM, Pollara J, Hryniewicz A, Ferrari G, Guan Y, Forthal DN, Venzon D, Fenizia C, Morgan T, Montefiori D, Lifson JD, et al. Protection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposure. Journal of Virology. 87: 3538-48. PMID 23325681 DOI: 10.1128/JVI.02863-12  0.6
2013 Pegu P, Vaccari M, Gordon S, Keele BF, Doster M, Guan Y, Ferrari G, Pal R, Ferrari MG, Whitney S, Hudacik L, Billings E, Rao M, Montefiori D, Tomaras G, et al. Antibodies with high avidity to the gp120 envelope protein in protection from simian immunodeficiency virus SIV(mac251) acquisition in an immunization regimen that mimics the RV-144 Thai trial. Journal of Virology. 87: 1708-19. PMID 23175374 DOI: 10.1128/JVI.02544-12  0.6
2013 Breed MW, Jordan AP, Aye PP, Lichtveld CF, Midkiff CC, Schiro FR, Haggarty BS, Sugimoto C, Alvarez X, Sandler NG, Douek DC, Kuroda MJ, Pahar B, Piatak M, Lifson JD, ... Keele BF, et al. Loss of a tyrosine-dependent trafficking motif in the simian immunodeficiency virus envelope cytoplasmic tail spares mucosal CD4 cells but does not prevent disease progression. Journal of Virology. 87: 1528-43. PMID 23152518 DOI: 10.1128/JVI.01928-12  0.6
2013 Baalwa J, Wang S, Parrish NF, Decker JM, Keele BF, Learn GH, Yue L, Ruzagira E, Ssemwanga D, Kamali A, Amornkul PN, Price MA, Kappes JC, Karita E, Kaleebu P, et al. Molecular identification, cloning and characterization of transmitted/founder HIV-1 subtype A, D and A/D infectious molecular clones. Virology. 436: 33-48. PMID 23123038 DOI: 10.1016/j.virol.2012.10.009  0.6
2012 Li Y, Ndjango JB, Learn GH, Ramirez MA, Keele BF, Bibollet-Ruche F, Liu W, Easlick JL, Decker JM, Rudicell RS, Inogwabini BI, Ahuka-Mundeke S, Leendertz FH, Reynolds V, Muller MN, et al. Eastern chimpanzees, but not bonobos, represent a simian immunodeficiency virus reservoir. Journal of Virology. 86: 10776-91. PMID 22837215 DOI: 10.1128/JVI.01498-12  0.6
2012 Bar KJ, Tsao CY, Iyer SS, Decker JM, Yang Y, Bonsignori M, Chen X, Hwang KK, Montefiori DC, Liao HX, Hraber P, Fischer W, Li H, Wang S, Sterrett S, ... Keele BF, et al. Early low-titer neutralizing antibodies impede HIV-1 replication and select for virus escape. Plos Pathogens. 8: e1002721. PMID 22693447 DOI: 10.1371/journal.ppat.1002721  0.6
2012 Gautam R, Nishimura Y, Lee WR, Donau O, Buckler-White A, Shingai M, Sadjadpour R, Schmidt SD, LaBranche CC, Keele BF, Montefiori D, Mascola JR, Martin MA. Pathogenicity and mucosal transmissibility of the R5-tropic simian/human immunodeficiency virus SHIV(AD8) in rhesus macaques: implications for use in vaccine studies. Journal of Virology. 86: 8516-26. PMID 22647691 DOI: 10.1128/JVI.00644-12  0.6
2012 Bibollet-Ruche F, Heigele A, Keele BF, Easlick JL, Decker JM, Takehisa J, Learn G, Sharp PM, Hahn BH, Kirchhoff F. Efficient SIVcpz replication in human lymphoid tissue requires viral matrix protein adaptation. The Journal of Clinical Investigation. 122: 1644-52. PMID 22505456 DOI: 10.1172/JCI61429  0.6
2012 Wu X, Wang C, O'Dell S, Li Y, Keele BF, Yang Z, Imamichi H, Doria-Rose N, Hoxie JA, Connors M, Shaw GM, Wyatt RT, Mascola JR. Selection pressure on HIV-1 envelope by broadly neutralizing antibodies to the conserved CD4-binding site. Journal of Virology. 86: 5844-56. PMID 22419808 DOI: 10.1128/JVI.07139-11  0.6
2012 Xiao P, Patterson LJ, Kuate S, Brocca-Cofano E, Thomas MA, Venzon D, Zhao J, DiPasquale J, Fenizia C, Lee EM, Kalisz I, Kalyanaraman VS, Pal R, Montefiori D, Keele BF, et al. Replicating adenovirus-simian immunodeficiency virus (SIV) recombinant priming and envelope protein boosting elicits localized, mucosal IgA immunity in rhesus macaques correlated with delayed acquisition following a repeated low-dose rectal SIV(mac251) challenge. Journal of Virology. 86: 4644-57. PMID 22345466 DOI: 10.1128/JVI.06812-11  0.6
2012 Del Prete GQ, Kearney MF, Spindler J, Wiegand A, Chertova E, Roser JD, Estes JD, Hao XP, Trubey CM, Lara A, Lee K, Chaipan C, Bess JW, Nagashima K, Keele BF, et al. Restricted replication of xenotropic murine leukemia virus-related virus in pigtailed macaques. Journal of Virology. 86: 3152-66. PMID 22238316 DOI: 10.1128/JVI.06886-11  0.6
2012 Ochsenbauer C, Edmonds TG, Ding H, Keele BF, Decker J, Salazar MG, Salazar-Gonzalez JF, Shattock R, Haynes BF, Shaw GM, Hahn BH, Kappes JC. Generation of transmitted/founder HIV-1 infectious molecular clones and characterization of their replication capacity in CD4 T lymphocytes and monocyte-derived macrophages. Journal of Virology. 86: 2715-28. PMID 22190722 DOI: 10.1128/JVI.06157-11  0.6
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2012 Lee HY, Giorgi EE, Keele BF, Gaschen B, Athreya GS, Salazar-Gonzalez JF, Pham KT, Goepfert PA, Kilby JM, Saag MS, Delwart EL, Busch MP, Hahn BH, Shaw GM, Korber BT, et al. Corrigendum to "Modeling sequence evolution in acute HIV-1 infection" [J. Theor. Biol. 261 (2009) 341-360] Journal of Theoretical Biology. 297: 187. DOI: 10.1016/j.jtbi.2011.12.010  0.6
2011 Terio KA, Kinsel MJ, Raphael J, Mlengeya T, Lipende I, Kirchhoff CA, Gilagiza B, Wilson ML, Kamenya S, Estes JD, Keele BF, Rudicell RS, Liu W, Patton S, Collins A, et al. Pathologic lesions in chimpanzees (Pan trogylodytes schweinfurthii) from Gombe National Park, Tanzania, 2004-2010. Journal of Zoo and Wildlife Medicine : Official Publication of the American Association of Zoo Veterinarians. 42: 597-607. PMID 22204054 DOI: 10.1638/2010-0237.1  0.6
2011 Gnanakaran S, Bhattacharya T, Daniels M, Keele BF, Hraber PT, Lapedes AS, Shen T, Gaschen B, Krishnamoorthy M, Li H, Decker JM, Salazar-Gonzalez JF, Wang S, Jiang C, Gao F, et al. Recurrent signature patterns in HIV-1 B clade envelope glycoproteins associated with either early or chronic infections. Plos Pathogens. 7: e1002209. PMID 21980282 DOI: 10.1371/journal.ppat.1002209  0.6
2011 Fenizia C, Keele BF, Nichols D, Cornara S, Binello N, Vaccari M, Pegu P, Robert-Guroff M, Ma ZM, Miller CJ, Venzon D, Hirsch V, Franchini G. TRIM5α does not affect simian immunodeficiency virus SIV(mac251) replication in vaccinated or unvaccinated Indian rhesus macaques following intrarectal challenge exposure. Journal of Virology. 85: 12399-409. PMID 21917950 DOI: 10.1128/JVI.05707-11  0.6
2011 Asmal M, Hellmann I, Liu W, Keele BF, Perelson AS, Bhattacharya T, Gnanakaran S, Daniels M, Haynes BF, Korber BT, Hahn BH, Shaw GM, Letvin NL. A signature in HIV-1 envelope leader peptide associated with transition from acute to chronic infection impacts envelope processing and infectivity. Plos One. 6: e23673. PMID 21876761 DOI: 10.1371/journal.pone.0023673  0.6
2011 Pandrea I, Gaufin T, Gautam R, Kristoff J, Mandell D, Montefiori D, Keele BF, Ribeiro RM, Veazey RS, Apetrei C. Functional cure of SIVagm infection in rhesus macaques results in complete recovery of CD4+ T cells and is reverted by CD8+ cell depletion. Plos Pathogens. 7: e1002170. PMID 21829366 DOI: 10.1371/journal.ppat.1002170  0.6
2011 Ma ZM, Keele BF, Qureshi H, Stone M, Desilva V, Fritts L, Lifson JD, Miller CJ. SIVmac251 is inefficiently transmitted to rhesus macaques by penile inoculation with a single SIVenv variant found in ramp-up phase plasma. Aids Research and Human Retroviruses. 27: 1259-69. PMID 21732792 DOI: 10.1089/aid.2011.0090  0.6
2011 Burton DR, Hessell AJ, Keele BF, Klasse PJ, Ketas TA, Moldt B, Dunlop DC, Poignard P, Doyle LA, Cavacini L, Veazey RS, Moore JP. Limited or no protection by weakly or nonneutralizing antibodies against vaginal SHIV challenge of macaques compared with a strongly neutralizing antibody. Proceedings of the National Academy of Sciences of the United States of America. 108: 11181-6. PMID 21690411 DOI: 10.1073/pnas.1103012108  0.6
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2011 Keele BF, Estes JD. Barriers to mucosal transmission of immunodeficiency viruses. Blood. 118: 839-46. PMID 21555745 DOI: 10.1182/blood-2010-12-325860  0.6
2010 Rudicell RS, Holland Jones J, Wroblewski EE, Learn GH, Li Y, Robertson JD, Greengrass E, Grossmann F, Kamenya S, Pintea L, Mjungu DC, Lonsdorf EV, Mosser A, Lehman C, Collins DA, ... Keele BF, et al. Impact of simian immunodeficiency virus infection on chimpanzee population dynamics. Plos Pathogens. 6: e1001116. PMID 20886099 DOI: 10.1371/journal.ppat.1001116  0.6
2010 Liu W, Li Y, Learn GH, Rudicell RS, Robertson JD, Keele BF, Ndjango JB, Sanz CM, Morgan DB, Locatelli S, Gonder MK, Kranzusch PJ, Walsh PD, Delaporte E, Mpoudi-Ngole E, et al. Origin of the human malaria parasite Plasmodium falciparum in gorillas. Nature. 467: 420-5. PMID 20864995 DOI: 10.1038/nature09442  0.6
2010 Fischer W, Ganusov VV, Giorgi EE, Hraber PT, Keele BF, Leitner T, Han CS, Gleasner CD, Green L, Lo CC, Nag A, Wallstrom TC, Wang S, McMichael AJ, Haynes BF, et al. Transmission of single HIV-1 genomes and dynamics of early immune escape revealed by ultra-deep sequencing. Plos One. 5: e12303. PMID 20808830 DOI: 10.1371/journal.pone.0012303  0.6
2010 Liu J, Keele BF, Li H, Keating S, Norris PJ, Carville A, Mansfield KG, Tomaras GD, Haynes BF, Kolodkin-Gal D, Letvin NL, Hahn BH, Shaw GM, Barouch DH. Low-dose mucosal simian immunodeficiency virus infection restricts early replication kinetics and transmitted virus variants in rhesus monkeys. Journal of Virology. 84: 10406-12. PMID 20686016 DOI: 10.1128/JVI.01155-10  0.6
2010 Keele BF. Identifying and characterizing recently transmitted viruses. Current Opinion in Hiv and Aids. 5: 327-34. PMID 20543609 DOI: 10.1097/COH.0b013e32833a0b9b  0.6
2010 Li H, Bar KJ, Wang S, Decker JM, Chen Y, Sun C, Salazar-Gonzalez JF, Salazar MG, Learn GH, Morgan CJ, Schumacher JE, Hraber P, Giorgi EE, Bhattacharya T, Korber BT, ... ... Keele BF, et al. High Multiplicity Infection by HIV-1 in Men Who Have Sex with Men. Plos Pathogens. 6: e1000890. PMID 20485520 DOI: 10.1371/journal.ppat.1000890  0.6
2010 Stone M, Keele BF, Ma ZM, Bailes E, Dutra J, Hahn BH, Shaw GM, Miller CJ. A limited number of simian immunodeficiency virus (SIV) env variants are transmitted to rhesus macaques vaginally inoculated with SIVmac251. Journal of Virology. 84: 7083-95. PMID 20463069 DOI: 10.1128/JVI.00481-10  0.6
2010 Bar KJ, Li H, Chamberland A, Tremblay C, Routy JP, Grayson T, Sun C, Wang S, Learn GH, Morgan CJ, Schumacher JE, Haynes BF, Keele BF, Hahn BH, Shaw GM. Wide variation in the multiplicity of HIV-1 infection among injection drug users. Journal of Virology. 84: 6241-7. PMID 20375173 DOI: 10.1128/JVI.00077-10  0.6
2010 Yeh WW, Rahman I, Hraber P, Coffey RT, Nevidomskyte D, Giri A, Asmal M, Miljkovic S, Daniels M, Whitney JB, Keele BF, Hahn BH, Korber BT, Shaw GM, Seaman MS, et al. Autologous neutralizing antibodies to the transmitted/founder viruses emerge late after simian immunodeficiency virus SIVmac251 infection of rhesus monkeys. Journal of Virology. 84: 6018-32. PMID 20357097 DOI: 10.1128/JVI.02741-09  0.6
2010 Kraus MH, Parrish NF, Shaw KS, Decker JM, Keele BF, Salazar-Gonzalez JF, Grayson T, McPherson DT, Ping LH, Anderson JA, Swanstrom R, Williamson C, Shaw GM, Hahn BH. A rev1-vpu polymorphism unique to HIV-1 subtype A and C strains impairs envelope glycoprotein expression from rev-vpu-env cassettes and reduces virion infectivity in pseudotyping assays. Virology. 397: 346-57. PMID 20003995 DOI: 10.1016/j.virol.2009.11.019  0.6
2010 Blinkova O, Victoria J, Li Y, Keele BF, Sanz C, Ndjango JB, Peeters M, Travis D, Lonsdorf EV, Wilson ML, Pusey AE, Hahn BH, Delwart EL. Novel circular DNA viruses in stool samples of wild-living chimpanzees. The Journal of General Virology. 91: 74-86. PMID 19759238 DOI: 10.1099/vir.0.015446-0  0.6
2009 Keele BF, Derdeyn CA. Genetic and antigenic features of the transmitted virus. Current Opinion in Hiv and Aids. 4: 352-7. PMID 20048697 DOI: 10.1097/COH.0b013e32832d9fef  0.6
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2009 Keele BF, Li H, Learn GH, Hraber P, Giorgi EE, Grayson T, Sun C, Chen Y, Yeh WW, Letvin NL, Mascola JR, Nabel GJ, Haynes BF, Bhattacharya T, Perelson AS, et al. Low-dose rectal inoculation of rhesus macaques by SIVsmE660 or SIVmac251 recapitulates human mucosal infection by HIV-1. The Journal of Experimental Medicine. 206: 1117-34. PMID 19414559 DOI: 10.1084/jem.20082831  0.6
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2009 Abrahams MR, Anderson JA, Giorgi EE, Seoighe C, Mlisana K, Ping LH, Athreya GS, Treurnicht FK, Keele BF, Wood N, Salazar-Gonzalez JF, Bhattacharya T, Chu H, Hoffman I, Galvin S, et al. Quantitating the multiplicity of infection with human immunodeficiency virus type 1 subtype C reveals a non-poisson distribution of transmitted variants. Journal of Virology. 83: 3556-67. PMID 19193811 DOI: 10.1128/JVI.02132-08  0.6
2009 Shen X, Parks RJ, Montefiori DC, Kirchherr JL, Keele BF, Decker JM, Blattner WA, Gao F, Weinhold KJ, Hicks CB, Greenberg ML, Hahn BH, Shaw GM, Haynes BF, Tomaras GD. In vivo gp41 antibodies targeting the 2F5 monoclonal antibody epitope mediate human immunodeficiency virus type 1 neutralization breadth. Journal of Virology. 83: 3617-25. PMID 19193787 DOI: 10.1128/JVI.02631-08  0.6
2009 Haaland RE, Hawkins PA, Salazar-Gonzalez J, Johnson A, Tichacek A, Karita E, Manigart O, Mulenga J, Keele BF, Shaw GM, Hahn BH, Allen SA, Derdeyn CA, Hunter E. Inflammatory genital infections mitigate a severe genetic bottleneck in heterosexual transmission of subtype A and C HIV-1. Plos Pathogens. 5: e1000274. PMID 19165325 DOI: 10.1371/journal.ppat.1000274  0.6
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2008 Liu W, Worobey M, Li Y, Keele BF, Bibollet-Ruche F, Guo Y, Goepfert PA, Santiago ML, Ndjango JB, Neel C, Clifford SL, Sanz C, Kamenya S, Wilson ML, Pusey AE, et al. Molecular ecology and natural history of simian foamy virus infection in wild-living chimpanzees. Plos Pathogens. 4: e1000097. PMID 18604273 DOI: 10.1371/journal.ppat.1000097  0.6
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2004 Worobey M, Santiago ML, Keele BF, Ndjango JBN, Joy JB, Labama BL, Dhed'a BD, Rambaut A, Sharp PM, Shaw GM, Hahn BH. Contaminated polio vaccine theory refuted Nature. 428: 820. PMID 15103367 DOI: 10.1038/428820a  0.6
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