Heather M. Wilkins, Ph.D. - Publications

Affiliations: 
2013 Biological Sciences University of Denver, Denver, CO, United States 
Area:
Neuroscience Biology, Biochemistry

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Morris JK, John CS, Green ZD, Wilkins HM, Wang X, Kamat A, Swerdlow RS, Vidoni ED, Petersen ME, O'Bryant SE, Honea RA, Burns JM. Characterization of the Meal-Stimulated Incretin Response and Relationship With Structural Brain Outcomes in Aging and Alzheimer's Disease. Frontiers in Neuroscience. 14: 608862. PMID 33328877 DOI: 10.3389/fnins.2020.608862  0.84
2020 Flax J, Wilkins HM, Miller R, Griffith S, Cork GK, Qiang A, Thompson J, Swerdlow RH, Slawson C. OGA Inhibition Alters Energetics and Nutrient Sensing in Alzheimer's Disease Cytoplasmic Hybrids. Journal of Alzheimer's Disease : Jad. PMID 33285636 DOI: 10.3233/JAD-200996  0.92
2020 Wang X, Weidling I, Koppel S, Menta B, Perez Ortiz J, Kalani A, Wilkins HM, Swerdlow RH. Detection of Mitochondria-Pertinent Components in Exosomes. Mitochondrion. PMID 32980480 DOI: 10.1016/j.mito.2020.09.006  0.92
2020 Vidoni ED, Choi IY, Lee P, Reed G, Zhang N, Pleen J, Mahnken JD, Clutton J, Becker A, Sherry E, Bothwell R, Anderson H, Harris RA, Brooks W, Wilkins HM, et al. Safety and target engagement profile of two oxaloacetate doses in Alzheimer's patients. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32715609 DOI: 10.1002/alz.12156  0.92
2020 Swerdlow RH, Hui D, Chalise P, Sharma P, Wang X, Andrews SJ, Pa J, Mahnken JD, Morris J, Wilkins HM, Burns JM, Michaelis ML, Michaelis EK. Exploratory analysis of mtDNA haplogroups in two Alzheimer's longitudinal cohorts. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32543785 DOI: 10.1002/alz.12119  0.92
2019 Watts A, Wilkins HM, Michaelis E, Swerdlow RH. TOMM40 '523 Associations with Baseline and Longitudinal Cognition in APOE ɛ3 Homozygotes. Journal of Alzheimer's Disease : Jad. PMID 31322569 DOI: 10.3233/JAD-190293  0.92
2019 Ji Y, Wang X, Kalicki C, Menta BW, Baumgardner M, Koppel SJ, Weidling IW, Perez-Ortiz J, Wilkins HM, Swerdlow RH. Effects of Microglial Cytokines on Alzheimer's Disease-Related Phenomena. Journal of Alzheimer's Disease : Jad. PMID 30714956 DOI: 10.3233/JAD-180820  0.92
2018 Kumar RP, Ray S, Home P, Saha B, Bhattacharya B, Wilkins HM, Chavan H, Ganguly A, Milano-Foster J, Paul A, Krishnamurthy P, Swerdlow RH, Paul S. Regulation of energy metabolism during early mammalian development: TEAD4 controls mitochondrial transcription. Development (Cambridge, England). PMID 30201685 DOI: 10.1242/dev.162644  0.92
2018 Statland JM, Moore D, Wang Y, Walsh M, Mozaffar T, Elman L, Nations S, Mitsumoto H, Fernandes JA, Saperstein D, Hayat G, Herbelin L, Karam C, Katz J, Wilkins HM, et al. Rasagiline for Amyotrophic Lateral Sclerosis: a Randomized Controlled Trial. Muscle & Nerve. PMID 30192007 DOI: 10.1002/mus.26335  0.92
2018 Brinkley TE, Berger M, Callahan KE, Fieo RA, Jennings LA, Morris JK, Wilkins HM, Kritchevsky SB. Corrigendum to: Workshop on Synergies Between Alzheimer's Research and Clinical Gerontology and Geriatrics: Current Status and Future Directions. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 30137213 DOI: 10.1093/gerona/gly156  0.4
2018 Brinkley TE, Berger MS, Callahan KE, Fieo RA, Jennings LA, Morris JK, Wilkins HM, Kritchevsky SB. Workshop on Synergies Between Alzheimer's Research and Clinical Gerontology and Geriatrics: Current Status and Future Directions. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 29982466 DOI: 10.1093/gerona/gly041  0.4
2018 Duval N, Sumner WA, Andrianakos AG, Gray JJ, Bouchard RJ, Wilkins HM, Linseman DA. The Bcl-2 Homology-3 Domain (BH3)-Only Proteins, Bid, DP5/Hrk, and BNip3L, Are Upregulated in Reactive Astrocytes of End-Stage Mutant SOD1 Mouse Spinal Cord. Frontiers in Cellular Neuroscience. 12: 15. PMID 29440992 DOI: 10.3389/fncel.2018.00015  1
2017 Ma E, Chen P, Wilkins HM, Wang T, Swerdlow RH, Chen Q. Pharmacologic ascorbate induces neuroblastoma cell death by hydrogen peroxide mediated DNA damage and reduction in cancer cell glycolysis. Free Radical Biology & Medicine. PMID 28916476 DOI: 10.1016/j.freeradbiomed.2017.09.008  0.92
2017 Winter AN, Ross EK, Daliparthi V, Sumner WA, Kirchhof DM, Manning E, Wilkins HM, Linseman DA. A Cystine-Rich Whey Supplement (Immunocal®) Provides Neuroprotection from Diverse Oxidative Stress-Inducing Agents In Vitro by Preserving Cellular Glutathione. Oxidative Medicine and Cellular Longevity. 2017: 3103272. PMID 28894506 DOI: 10.1155/2017/3103272  1
2017 Wang X, Zhang Q, Bao R, Zhang N, Wang Y, Polo-Parada L, Tarim A, Alemifar A, Han X, Wilkins HM, Swerdlow RH, Wang X, Ding S. Deletion of Nampt in Projection Neurons of Adult Mice Leads to Motor Dysfunction, Neurodegeneration, and Death. Cell Reports. 20: 2184-2200. PMID 28854367 DOI: 10.1016/j.celrep.2017.08.022  0.92
2017 Wilkins HM, Mahnken JD, Welch P, Bothwell R, Koppel S, Jackson RL, Burns JM, Swerdlow RH. A Mitochondrial Biomarker-Based Study of S-Equol in Alzheimer's Disease Subjects: Results of a Single-Arm, Pilot Trial. Journal of Alzheimer's Disease : Jad. PMID 28598847 DOI: 10.3233/JAD-170077  0.92
2017 Morris K J, Uy RAZ, Vidoni ED, Wilkins HM, Archer AE, Thyfault JP, Miles JM, Burns JM. Effect of APOE ε4 Genotype on Metabolic Biomarkers in Aging and Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 28550261 DOI: 10.3233/JAD-170148  0.6
2017 Hutfles LJ, Wilkins HM, Koppel SJ, Weidling IW, Selfridge JE, Tan E, Thyfault JP, Slawson C, Fenton AW, Zhu H, Swerdlow RH. A Bioenergetics Systems Evaluation of Ketogenic Diet Liver Effects. Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme. PMID 28514599 DOI: 10.1139/apnm-2017-0068  0.92
2017 Wilkins HM, Weidling IW, Ji Y, Swerdlow RH. Mitochondria-Derived Damage-Associated Molecular Patterns in Neurodegeneration. Frontiers in Immunology. 8: 508. PMID 28491064 DOI: 10.3389/fimmu.2017.00508  0.92
2017 Wilkins HM, Koppel SJ, Bothwell R, Mahnken J, Burns JM, Swerdlow RH. Platelet cytochrome oxidase and citrate synthase activities in APOE ε4 carrier and non-carrier Alzheimer's disease patients. Redox Biology. 12: 828-832. PMID 28448944 DOI: 10.1016/j.redox.2017.04.010  0.92
2017 Winter AN, Ross EK, Wilkins HM, Stankiewicz TR, Wallace T, Miller K, Linseman DA. An anthocyanin-enriched extract from strawberries delays disease onset and extends survival in the hSOD1(G93A) mouse model of amyotrophic lateral sclerosis. Nutritional Neuroscience. 1-13. PMID 28276271 DOI: 10.1080/1028415X.2017.1297023  1
2017 Swerdlow RH, Koppel S, Weidling I, Hayley C, Ji Y, Wilkins HM. Mitochondria, Cybrids, Aging, and Alzheimer's Disease. Progress in Molecular Biology and Translational Science. 146: 259-302. PMID 28253988 DOI: 10.1016/bs.pmbts.2016.12.017  0.92
2017 Morris JK, Vidoni ED, Johnson DK, Van Sciver A, Mahnken JD, Honea RA, Wilkins HM, Brooks WM, Billinger SA, Swerdlow RH, Burns JM. Aerobic exercise for Alzheimer's disease: A randomized controlled pilot trial. Plos One. 12: e0170547. PMID 28187125 DOI: 10.1371/journal.pone.0170547  0.92
2016 Wilkins HM, Morris JK. New Therapeutics to Modulate Mitochondrial Function in Neurodegenerative Disorders. Current Pharmaceutical Design. PMID 28034353  0.4
2016 Wilkins HM, Koppel SJ, Weidling IW, Roy N, Ryan LN, Stanford JA, Swerdlow RH. Extracellular Mitochondria and Mitochondrial Components Act as Damage-Associated Molecular Pattern Molecules in the Mouse Brain. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 27562848 DOI: 10.1007/s11481-016-9704-7  1
2016 Wilkins HM, Swerdlow RH. Amyloid Precursor Protein Processing and Bioenergetics. Brain Research Bulletin. PMID 27545490 DOI: 10.1016/j.brainresbull.2016.08.009  0.92
2016 Morris JK, Vidoni ED, Wilkins HM, Archer AE, Burns NC, Karcher RT, Graves RS, Swerdlow RH, Thyfault JP, Burns JM. Impaired fasting glucose is associated with increased regional cerebral amyloid. Neurobiology of Aging. 44: 138-42. PMID 27318141 DOI: 10.1016/j.neurobiolaging.2016.04.017  0.92
2016 Wilkins HM, Koppel S, Carl SM, Ramanujan S, Weidling I, Michaelis ML, Michaelis EK, Swerdlow RH. Oxaloacetate Enhances Neuronal Cell Bioenergetic Fluxes and Infrastructure. Journal of Neurochemistry. PMID 26811028 DOI: 10.1111/jnc.13545  1
2016 Wilkins HM, Swerdlow RH. Relationships Between Mitochondria and Neuroinflammation: Implications for Alzheimer's Disease. Current Topics in Medicinal Chemistry. 16: 849-57. PMID 26311426  1
2016 Morris JK, Vidoni ED, Wilkins HM, Archer AE, Burns NC, Karcher RT, Graves RS, Swerdlow RH, Thyfault JP, Burns JM. Impaired fasting glucose is associated with increased regional cerebral amyloid Neurobiology of Aging. 44: 138-142. DOI: 10.1016/j.neurobiolaging.2016.04.017  0.88
2015 Macchi Z, Wang Y, Moore D, Katz J, Saperstein D, Walk D, Simpson E, Genge A, Bertorini T, Fernandes JA, Swenson A, Elman L, Dimachkie M, Herbelin L, Miller J, ... ... Wilkins H, et al. A multi-center screening trial of rasagiline in patients with amyotrophic lateral sclerosis: Possible mitochondrial biomarker target engagement. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 1-8. PMID 25832828 DOI: 10.3109/21678421.2015.1026826  0.92
2015 Wilkins HM, Swerdlow RH. TNFα in cerebral ischemia: another stroke against you? Journal of Neurochemistry. 132: 369-72. PMID 25656781 DOI: 10.1111/jnc.13028  0.88
2015 Wilkins HM, Carl SM, Weber SG, Ramanujan SA, Festoff BW, Linseman DA, Swerdlow RH. Mitochondrial lysates induce inflammation and Alzheimer's disease-relevant changes in microglial and neuronal cells. Journal of Alzheimer's Disease : Jad. 45: 305-18. PMID 25537010 DOI: 10.3233/JAD-142334  1
2015 Selfridge JE, Wilkins HM, E L, Carl SM, Koppel S, Funk E, Fields T, Lu J, Tang EP, Slawson C, Wang W, Zhu H, Swerdlow RH. Effect of one month duration ketogenic and non-ketogenic high fat diets on mouse brain bioenergetic infrastructure. Journal of Bioenergetics and Biomembranes. 47: 1-11. PMID 25104046 DOI: 10.1007/s10863-014-9570-z  1
2014 Ross EK, Winter AN, Wilkins HM, Sumner WA, Duval N, Patterson D, Linseman DA. A Cystine-Rich Whey Supplement (Immunocal(®)) Delays Disease Onset and Prevents Spinal Cord Glutathione Depletion in the hSOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis. Antioxidants (Basel, Switzerland). 3: 843-65. PMID 26785244 DOI: 10.3390/antiox3040843  1
2014 Wilkins HM, Carl SM, Swerdlow RH. Cytoplasmic hybrid (cybrid) cell lines as a practical model for mitochondriopathies. Redox Biology. 2: 619-631. PMID 25460729 DOI: 10.1016/j.redox.2014.03.006  1
2014 Wilkins HM, Carl SM, Greenlief AC, Festoff BW, Swerdlow RH. Bioenergetic dysfunction and inflammation in Alzheimer's disease: a possible connection. Frontiers in Aging Neuroscience. 6: 311. PMID 25426068 DOI: 10.3389/fnagi.2014.00311  1
2014 Wilkins HM, Harris JL, Carl SM, E L, Lu J, Eva Selfridge J, Roy N, Hutfles L, Koppel S, Morris J, Burns JM, Michaelis ML, Michaelis EK, Brooks WM, Swerdlow RH. Oxaloacetate activates brain mitochondrial biogenesis, enhances the insulin pathway, reduces inflammation and stimulates neurogenesis. Human Molecular Genetics. 23: 6528-41. PMID 25027327 DOI: 10.1093/hmg/ddu371  1
2014 Wilkins HM, Brock S, Gray JJ, Linseman DA. Stable over-expression of the 2-oxoglutarate carrier enhances neuronal cell resistance to oxidative stress via Bcl-2-dependent mitochondrial GSH transport. Journal of Neurochemistry. 130: 75-86. PMID 24606213 DOI: 10.1111/jnc.12709  1
2013 Wilkins HM, Kirchhof D, Manning E, Joseph JW, Linseman DA. Mitochondrial glutathione transport is a key determinant of neuronal susceptibility to oxidative and nitrosative stress. The Journal of Biological Chemistry. 288: 5091-101. PMID 23283974 DOI: 10.1074/jbc.M112.405738  1
2012 Bartley MG, Marquardt K, Kirchhof D, Wilkins HM, Patterson D, Linseman DA. Overexpression of amyloid-β protein precursor induces mitochondrial oxidative stress and activates the intrinsic apoptotic cascade. Journal of Alzheimer's Disease : Jad. 28: 855-68. PMID 22133762 DOI: 10.3233/JAD-2011-111172  1
2012 Wilkins HM, Marquardt K, Lash LH, Linseman DA. Bcl-2 is a novel interacting partner for the 2-oxoglutarate carrier and a key regulator of mitochondrial glutathione. Free Radical Biology & Medicine. 52: 410-9. PMID 22115789 DOI: 10.1016/j.freeradbiomed.2011.10.495  1
2011 Harbison RA, Ryan KR, Wilkins HM, Schroeder EK, Loucks FA, Bouchard RJ, Linseman DA. Calpain plays a central role in 1-methyl-4-phenylpyridinium (MPP+)-induced neurotoxicity in cerebellar granule neurons. Neurotoxicity Research. 19: 374-88. PMID 20333497 DOI: 10.1007/s12640-010-9172-4  1
2010 Kelsey NA, Wilkins HM, Linseman DA. Nutraceutical antioxidants as novel neuroprotective agents. Molecules (Basel, Switzerland). 15: 7792-814. PMID 21060289 DOI: 10.3390/molecules15117792  1
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