Stephen G. Aller, Ph.D. - Publications

Affiliations: 
2001-2006 Molecular Biophysics & Biochemistry Yale University, New Haven, CT 
 2009- Pharmacology & Toxicology University of Alabama, Birmingham, Birmingham, AL, United States 
Area:
General Biophysics, Biochemistry, Molecular Biology, Cell Biology, Structural Biology

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Radka CD, Aller SG. Site 2 of the Yersinia pestis substrate-binding protein YfeA is a dynamic surface metal-binding site. Acta Crystallographica. Section F, Structural Biology Communications. 77: 286-293. PMID 34473105 DOI: 10.1107/S2053230X21008086  1
2021 Bhanot S, Hemminger G, Martin CL, Aller SG, Forrest JN. A non-olfactory shark adenosine receptor activates CFTR with unique pharmacology and structural features. American Journal of Physiology. Cell Physiology. PMID 33689481 DOI: 10.1152/ajpcell.00481.2020  1
2020 Thomas C, Aller SG, Beis K, Carpenter EP, Chang G, Chen L, Dassa E, Dean M, Duong Van Hoa F, Ekiert D, Ford R, Gaudet R, Gong X, Holland IB, Huang Y, et al. Structural and functional diversity calls for a new classification of ABC transporters. Febs Letters. PMID 32978974 DOI: 10.1002/1873-3468.13935  0.01
2020 Le CA, Harvey DS, Aller SG. Structural definition of polyspecific compensatory ligand recognition by P-glycoprotein. Iucrj. 7: 663-672. PMID 32695413 DOI: 10.1107/S2052252520005709  0.01
2020 Doiron JE, Le CA, Bacsa J, Breton GW, Martin KL, Aller SG, Turlington M. Structural Consequences of the 1,2,3-Triazole as an Amide Bioisostere in Analogs of Cystic Fibrosis Drugs VX-809 and VX-770. Chemmedchem. PMID 32385907 DOI: 10.1002/Cmdc.202000220  0.01
2019 Radka CD, Labiuk SL, DeLucas LJ, Aller SG. Structures of the substrate-binding protein YfeA in apo and zinc-reconstituted holo forms. Acta Crystallographica. Section D, Structural Biology. 75: 831-840. PMID 31478906 DOI: 10.1107/S2059798319010866  1
2019 Doiron JE, Le CA, Ody BK, Brace JB, Post SJ, Thacker NL, Hill HM, Breton GW, Mulder MJ, Chang S, Bridges TM, Tang L, Wang W, Rowe SM, Aller SG, et al. Evaluation of 1,2,3-Triazoles as Amide Bioisosteres In Cystic Fibrosis Transmembrane Conductance Regulator Modulators VX-770 and VX-809. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 30650214 DOI: 10.1002/Chem.201805919  0.01
2018 Pan L, Aller SG. Allosteric Role of Substrate Occupancy Toward the Alignment of P-glycoprotein Nucleotide Binding Domains. Scientific Reports. 8: 14643. PMID 30279588 DOI: 10.1038/S41598-018-32815-2  1
2018 Skamel C, Aller SG, Bopda Waffo A. Correction: In Vitro Evolution and Affinity-Maturation with Coliphage Qβ Display. Plos One. 13: e0199953. PMID 29944705 DOI: 10.1371/Journal.Pone.0199953  1
2018 Radka CD, Radford LL, Massicano AVF, DeLucas LJ, Lapi SE, Aller SG. Essential Metal Uptake in Gram-negative Bacteria: X-ray Fluorescence, Radioisotopes, and Cell Fractionation. Journal of Visualized Experiments : Jove. PMID 29443084 DOI: 10.3791/57169  1
2017 Radka CD, Chen D, DeLucas LJ, Aller SG. The crystal structure of the Yersinia pestis iron chaperone YiuA reveals a basic triad binding motif for the chelated metal. Acta Crystallographica. Section D, Structural Biology. 73: 921-939. PMID 29095164 DOI: 10.1107/S2059798317015236  1
2017 Radka CD, DeLucas LJ, Wilson LS, Lawrenz MB, Perry RD, Aller SG. Crystal structure of Yersinia pestis virulence factor YfeA reveals two polyspecific metal-binding sites. Acta Crystallographica. Section D, Structural Biology. 73: 557-572. PMID 28695856 DOI: 10.1107/S2059798317006349  1
2015 Pan L, Aller SG. Tools and procedures for visualization of proteins and other biomolecules. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. 110: 19.12.1-19.12.47. PMID 25827086 DOI: 10.1002/0471142727.Mb1912S110  1
2015 Pan L, Aller SG. Equilibrated atomic models of outward-facing P-glycoprotein and effect of ATP binding on structural dynamics. Scientific Reports. 5: 7880. PMID 25600711 DOI: 10.1038/Srep07880  1
2015 Feduska JM, Aller SG, Garcia PL, Cramer SL, Council LN, van Waardenburg RC, Yoon KJ. ICAM-2 confers a non-metastatic phenotype in neuroblastoma cells by interaction with α-actinin. Oncogene. 34: 1553-62. PMID 24704826 DOI: 10.1038/Onc.2014.87  1
2014 Skamel C, Aller SG, Bopda Waffo A. In vitro evolution and affinity-maturation with Coliphage qβ display. Plos One. 9: e113069. PMID 25393763 DOI: 10.1371/Journal.Pone.0113069  1
2014 Li J, Jaimes KF, Aller SG. Refined structures of mouse P-glycoprotein. Protein Science : a Publication of the Protein Society. 23: 34-46. PMID 24155053 DOI: 10.1002/Pro.2387  1
2014 Feduska JM, Aller SG, Cramer S, Waardenburg RCAMv, Yoon KJ. Abstract 118: The cytoplasmic domain of ICAM-2 interacts with α-actinin to confer a non-metastatic phenotype in neuroblastoma cells Cancer Research. 74: 118-118. DOI: 10.1158/1538-7445.Am2014-118  1
2009 Clayton GM, Aller SG, Wang J, Unger V, Morais-Cabral JH. Combining electron crystallography and X-ray crystallography to study the MlotiK1 cyclic nucleotide-regulated potassium channel Journal of Structural Biology. 167: 220-226. PMID 19545635 DOI: 10.1016/J.Jsb.2009.06.012  1
2009 Aller SG, Yu J, Ward A, Weng Y, Chittaboina S, Zhuo R, Harrell PM, Trinh YT, Zhang Q, Urbatsch IL, Chang G. Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding. Science (New York, N.Y.). 323: 1718-22. PMID 19325113 DOI: 10.1126/Science.1168750  1
2009 De Feo CJ, Aller SG, Siluvai GS, Blackburn NJ, Unger VM. Three-dimensional structure of the human copper transporter hCTR1. Proceedings of the National Academy of Sciences of the United States of America. 106: 4237-42. PMID 19240214 DOI: 10.1073/Pnas.0810286106  1
2009 Feo CJD, Aller SG, Barkan Y, Shcushan M, Siluvai G, Ben-Tal N, Blackburn NJ, Unger VM. CTR Structure and Mechanism Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.004  1
2007 De Feo CJ, Aller SG, Unger VM. A structural perspective on copper uptake in eukaryotes. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 20: 705-16. PMID 17211682 DOI: 10.1007/S10534-006-9054-7  1
2006 Aller SG, Unger VM. Projection structure of the human copper transporter CTR1 at 6-A resolution reveals a compact trimer with a novel channel-like architecture. Proceedings of the National Academy of Sciences of the United States of America. 103: 3627-32. PMID 16501047 DOI: 10.1073/Pnas.0509929103  1
2006 Ratner MA, Decker SE, Aller SG, Weber G, Forrest JN. Mercury toxicity in the shark (Squalus acanthias) rectal gland: apical CFTR chloride channels are inhibited by mercuric chloride. Journal of Experimental Zoology. Part a, Comparative Experimental Biology. 305: 259-67. PMID 16432888 DOI: 10.1002/Jez.A.257  1
2006 Weber GJ, Mehr AP, Sirota JC, Aller SG, Decker SE, Dawson DC, Forrest JN. Mercury and zinc differentially inhibit shark and human CFTR orthologues: involvement of shark cysteine 102. American Journal of Physiology. Cell Physiology. 290: C793-801. PMID 16236827 DOI: 10.1152/Ajpcell.00203.2005  1
2004 Aller SG, Eng ET, De Feo CJ, Unger VM. Eukaryotic CTR copper uptake transporters require two faces of the third transmembrane domain for helix packing, oligomerization, and function. The Journal of Biological Chemistry. 279: 53435-41. PMID 15385536 DOI: 10.1074/Jbc.M409421200  1
2002 Marlovits TC, Haase W, Herrmann C, Aller SG, Unger VM. The membrane protein FeoB contains an intramolecular G protein essential for Fe(II) uptake in bacteria. Proceedings of the National Academy of Sciences of the United States of America. 99: 16243-8. PMID 12446835 DOI: 10.1073/Pnas.242338299  1
2002 Yang T, Forrest SJ, Stine N, Endo Y, Pasumarthy A, Castrop H, Aller S, Forrest JN, Schnermann JB, Briggs J. Cyclooxygenase cloning in dogfish shark, Squalus acanthias, and its role in rectal gland Cl secretion American Journal of Physiology-Regulatory Integrative and Comparative Physiology. 283. PMID 12184997 DOI: 10.1152/Ajpregu.00743.2001  1
1999 Aller SG, Lombardo ID, Bhanot S, Forrest JN. Cloning, characterization, and functional expression of a CNP receptor regulating CFTR in the shark rectal gland American Journal of Physiology - Cell Physiology. 276. PMID 9950772 DOI: 10.1152/Ajpcell.1999.276.2.C442  1
1999 Waldegger S, Fakler B, Bleich M, Barth P, Hopf A, Schulte U, Busch AE, Aller SG, Forrest JN, Greger R, Lang F. Molecular and functional characterization of s-KCNQ1 potassium channel from rectal gland of Squalus acanthias. PflüGers Archiv : European Journal of Physiology. 437: 298-304. PMID 9929573 DOI: 10.1007/S004240050783  1
1998 Lehrich RW, Aller SG, Webster P, Marino CR, Forrest JN. Vasoactive intestinal peptide, forskolin, and genistein increase apical CFTR trafficking in the rectal gland of the spiny dogfish, Squalus acanthias: Acute regulation of CFTR trafficking in an intact epithelium Journal of Clinical Investigation. 101: 737-745. PMID 9466967 DOI: 10.1172/Jci803  1
1997 Forrest JN, Aller SG, Wood SJ, Ratner MA, Forrest JK, Kelley GG. Cadmium disrupts the signal transduction pathway of both inhibitory and stimulatory receptors regulating chloride secretion in the shark rectal gland Journal of Experimental Zoology. 279: 530-536. PMID 9392874 DOI: 10.1002/(Sici)1097-010X(19971201)279:5<530::Aid-Jez17>3.0.Co;2-B  1
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