Yun-Ru Chen, Ph.D. - Publications

2003 North Carolina State University, Raleigh, NC 
Biochemistry, General Biophysics

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Thai NQ, Tseng NH, Vu MT, Nguyen TT, Linh HQ, Hu CK, Chen YR, Li MS. Discovery of DNA dyes Hoechst 34580 and 33342 as good candidates for inhibiting amyloid beta formation: in silico and in vitro study. Journal of Computer-Aided Molecular Design. PMID 27511370 DOI: 10.1007/s10822-016-9932-1  0.32
2016 Lee CW, Jang LL, Pan HJ, Chen YR, Chen CC, Lee CH. Membrane roughness as a sensitive parameter reflecting the status of neuronal cells in response to chemical and nanoparticle treatments. Journal of Nanobiotechnology. 14: 9. PMID 26821536 DOI: 10.1186/s12951-016-0161-5  0.32
2016 Chang YJ, Jeng US, Chiang YL, Hwang IS, Chen YR. Glycine-Alanine Dipeptide Repeat from C9orf72 Hexanucleotide Expansions Forms Toxic Amyloids Possessing Cell-to-cell Transmission Property. The Journal of Biological Chemistry. PMID 26769963 DOI: 10.1074/jbc.M115.694273  0.32
2015 Kao PF, Chen YR, Liu XB, DeCarli C, Seeley WW, Jin LW. Detection of TDP-43 oligomers in frontotemporal lobar degeneration-TDP. Annals of Neurology. 78: 211-21. PMID 25921485 DOI: 10.1002/ana.24431  0.32
2014 Fang YS, Tsai KJ, Chang YJ, Kao P, Woods R, Kuo PH, Wu CC, Liao JY, Chou SC, Lin V, Jin LW, Yuan HS, Cheng IH, Tu PH, Chen YR. Full-length TDP-43 forms toxic amyloid oligomers that are present in frontotemporal lobar dementia-TDP patients. Nature Communications. 5: 4824. PMID 25215604 DOI: 10.1038/ncomms5824  0.32
2014 Pan HJ, Wang RL, Xiao JL, Chang YJ, Cheng JY, Chen YR, Lee CH. Using optical profilometry to characterize cell membrane roughness influenced by amyloid-beta 42 aggregates and electric fields. Journal of Biomedical Optics. 19: 011009. PMID 23892727 DOI: 10.1117/1.JBO.19.1.011009  0.32
2013 Viet MH, Chen CY, Hu CK, Chen YR, Li MS. Discovery of dihydrochalcone as potential lead for Alzheimer's disease: in silico and in vitro study. Plos One. 8: e79151. PMID 24260164 DOI: 10.1371/journal.pone.0079151  0.32
2013 Cheng WC, Weng CY, Yun WY, Chang SY, Lin YC, Tsai FJ, Huang FY, Chen YR. Rapid modifications of N-substitution in iminosugars: development of new β-glucocerebrosidase inhibitors and pharmacological chaperones for Gaucher disease. Bioorganic & Medicinal Chemistry. 21: 5021-8. PMID 23880081 DOI: 10.1016/j.bmc.2013.06.054  0.32
2013 Chen RJ, Chang WW, Lin YC, Cheng PL, Chen YR. Alzheimer's amyloid-β oligomers rescue cellular prion protein induced tau reduction via the Fyn pathway. Acs Chemical Neuroscience. 4: 1287-96. PMID 23805846 DOI: 10.1021/cn400085q  0.32
2012 Chen WT, Hong CJ, Lin YT, Chang WH, Huang HT, Liao JY, Chang YJ, Hsieh YF, Cheng CY, Liu HC, Chen YR, Cheng IH. Amyloid-beta (Aβ) D7H mutation increases oligomeric Aβ42 and alters properties of Aβ-zinc/copper assemblies. Plos One. 7: e35807. PMID 22558227 DOI: 10.1371/journal.pone.0035807  0.32
2011 Chen WT, Liao YH, Yu HM, Cheng IH, Chen YR. Distinct effects of Zn2+, Cu2+, Fe3+, and Al3+ on amyloid-beta stability, oligomerization, and aggregation: amyloid-beta destabilization promotes annular protofibril formation. The Journal of Biological Chemistry. 286: 9646-56. PMID 21216965 DOI: 10.1074/jbc.M110.177246  0.32
2006 Chen YR, Glabe CG. Distinct early folding and aggregation properties of Alzheimer amyloid-beta peptides Abeta40 and Abeta42: stable trimer or tetramer formation by Abeta42. The Journal of Biological Chemistry. 281: 24414-22. PMID 16809342 DOI: 10.1074/jbc.M602363200  0.32
2006 Chen YR, Clark AC. Substitutions of prolines examine their role in kinetic trap formation of the caspase recruitment domain (CARD) of RICK. Protein Science : a Publication of the Protein Society. 15: 395-409. PMID 16501221 DOI: 10.1110/ps.051943006  0.32
2004 Chen YR, Clark AC. Kinetic traps in the folding/unfolding of procaspase-1 CARD domain. Protein Science : a Publication of the Protein Society. 13: 2196-206. PMID 15273313 DOI: 10.1110/ps.03521504  0.32
2004 Dang SS, Jia XL, Cheng YA, Chen YR, Liu EQ, Li ZF. Inhibitory effect of Huangqi Zhechong decoction on liver fibrosis in rat. World Journal of Gastroenterology. 10: 2295-8. PMID 15259087  0.32
2003 Chen YR, Clark AC. Equilibrium and kinetic folding of an alpha-helical Greek key protein domain: caspase recruitment domain (CARD) of RICK. Biochemistry. 42: 6310-20. PMID 12755636 DOI: 10.1021/bi0340752  0.32
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