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Damian Winston Young, Ph.D. - Publications

Affiliations: 
2004 North Carolina State University, Raleigh, NC 
 2005-2009 Chemical Biology Harvard University, Cambridge, MA, United States 
 2011- Pathology, Chemical Biology Baylor College of Medicine, Houston, TX 
Area:
Organic Chemistry
Website:
https://www.bcm.edu/people/view/damian-young-ph-d/02c710f0-40e7-11e3-9de7-005056b104be
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15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Wang Y, Wach JY, Sheehan P, Zhong C, Zhan C, Harris R, Almo SC, Bishop J, Haggarty SJ, Ramek A, Berry KN, O'Herin C, Koehler AN, Hung AW, Young DW. Diversity-Oriented Synthesis as a Strategy for Fragment Evolution against GSK3β. Acs Medicinal Chemistry Letters. 7: 852-6. PMID 27660690 DOI: 10.1021/Acsmedchemlett.6B00230  0.704
2013 Yuan Y, Hartland K, Boskovic Z, Wang Y, Walpita D, Lysy PA, Zhong C, Young DW, Kim YK, Tolliday NJ, Sokal EM, Schreiber SL, Wagner BK. A small-molecule inducer of PDX1 expression identified by high-throughput screening. Chemistry & Biology. 20: 1513-22. PMID 24290880 DOI: 10.1016/J.Chembiol.2013.10.013  0.628
2013 Wang Y, Jimenez M, Sheehan P, Zhong C, Hung AW, Tam CP, Young DW. Selective access to trisubstituted macrocyclic E- and Z-alkenes from the ring-closing metathesis of vinylsiloxanes. Organic Letters. 15: 1218-21. PMID 23448432 DOI: 10.1021/Ol400134D  0.584
2013 Zhong C, Wang Y, O'Herin C, Young DW. Synthesis of substituted morpholines using stereodivergent aza-michael reactions catalyzed by Brønsted acids Acs Catalysis. 3: 643-646. DOI: 10.1021/Cs400031P  0.591
2013 Comins DL, Higuchi K, Young DW. Dihydropyridine preparation and application in the synthesis of pyridine derivatives Advances in Heterocyclic Chemistry. 110: 175-235. DOI: 10.1016/B978-0-12-408100-0.00006-9  0.512
2011 Zhong C, Wang Y, Hung AW, Schreiber SL, Young DW. Diastereoselective control of intramolecular aza-Michael reactions using achiral catalysts. Organic Letters. 13: 5556-9. PMID 21916463 DOI: 10.1021/Ol202276H  0.634
2011 Pandya BA, Dandapani S, Duvall JR, Rowley A, Mulrooney CA, Ryba T, Dombrowski M, Harton M, Young DW, Marcaurelle LA. Practical asymmetric synthesis of β-hydroxy γ-amino acids via complimentary aldol reactions. Tetrahedron. 67: 6131-6137. PMID 21822337 DOI: 10.1016/J.Tet.2011.06.043  0.34
2011 Wang Y, Jimenez M, Hansen AS, Raiber EA, Schreiber SL, Young DW. Control of olefin geometry in macrocyclic ring-closing metathesis using a removable silyl group. Journal of the American Chemical Society. 133: 9196-9. PMID 21557625 DOI: 10.1021/Ja202012S  0.633
2011 Hung AW, Ramek A, Wang Y, Kaya T, Wilson JA, Clemons PA, Young DW. Route to three-dimensional fragments using diversity-oriented synthesis. Proceedings of the National Academy of Sciences of the United States of America. 108: 6799-804. PMID 21482811 DOI: 10.1073/Pnas.1015271108  0.685
2010 Marcaurelle LA, Comer E, Dandapani S, Duvall JR, Gerard B, Kesavan S, Lee MD, Liu H, Lowe JT, Marie JC, Mulrooney CA, Pandya BA, Rowley A, Ryba TD, Suh BC, ... ... Young DW, et al. An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors. Journal of the American Chemical Society. 132: 16962-76. PMID 21067169 DOI: 10.1021/Ja105119R  0.601
2010 Dancík V, Seiler KP, Young DW, Schreiber SL, Clemons PA. Distinct biological network properties between the targets of natural products and disease genes. Journal of the American Chemical Society. 132: 9259-61. PMID 20565092 DOI: 10.1021/Ja102798T  0.6
2010 Young DW. Synthetic chemistry: An upfront investment. Nature Chemical Biology. 6: 174-175. PMID 20154664 DOI: 10.1038/Nchembio.325  0.341
2009 Kelly AR, Wei J, Kesavan S, Marié JC, Windmon N, Young DW, Marcaurelle LA. Accessing skeletal diversity using catalyst control: formation of n and n + 1 macrocyclic triazole rings. Organic Letters. 11: 2257-60. PMID 19473044 DOI: 10.1021/Ol900562U  0.321
2007 Bender A, Young DW, Jenkins JL, Serrano M, Mikhailov D, Clemons PA, Davies JW. Chemogenomic data analysis: prediction of small-molecule targets and the advent of biological fingerprint. Combinatorial Chemistry & High Throughput Screening. 10: 719-31. PMID 18045083 DOI: 10.2174/138620707782507313  0.556
2005 Young DW, Comins DL. Tandem directed lithiations of N-Boc-1,2-dihydropyridines toward highly functionalized 2,3-dihydro-4-pyridones. Organic Letters. 7: 5661-4. PMID 16321016 DOI: 10.1021/Ol052313A  0.538
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