Kevin Janes, Ph.D. - Related publications

Biomedical Engineering University of Virginia, Charlottesville, VA 
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Verma A, Jena SG, Isakov DR, Aoki K, Toettcher JE, Engelhardt BE. A self-exciting point process to study multicellular spatial signaling patterns. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34362843 DOI: 10.1073/pnas.2026123118   
2021 Wang S, Perkins NG, Ji F, Chaudhuri R, Guo Z, Sarkar P, Shao S, Li Z, Xue M. Digitonin-facilitated delivery of imaging probes enables single-cell analysis of AKT signalling activities in suspension cells. The Analyst. PMID 34351328 DOI: 10.1039/d1an00751c   
2021 Khoshkenar P, Lowry E, Mitchell A. Rapid signaling reactivation after targeted BRAF inhibition predicts the proliferation of individual melanoma cells from an isogenic population. Scientific Reports. 11: 15473. PMID 34326399 DOI: 10.1038/s41598-021-94941-8   
2021 Wang Y, Qiu F, Xu Y, Hou X, Zhang Z, Huang L, Wang H, Xing H, Wu S. Stem cell-like memory T cells: The generation and application. Journal of Leukocyte Biology. PMID 34402104 DOI: 10.1002/JLB.5MR0321-145R   
2021 Nagasawa S, Kashima Y, Suzuki A, Suzuki Y. Single-cell and spatial analyses of cancer cells: toward elucidating the molecular mechanisms of clonal evolution and drug resistance acquisition. Inflammation and Regeneration. 41: 22. PMID 34271973 DOI: 10.1186/s41232-021-00170-x   
2021 Wang F, Zhang Y, Yu X, Teng XL, Ding R, Hu Z, Wang A, Wang Z, Ye Y, Zou Q. ZFP91 disturbs metabolic fitness and antitumor activity of tumor-infiltrating T cells. The Journal of Clinical Investigation. PMID 34403361 DOI: 10.1172/JCI144318   
2021 Maradiaga ODH, Mok PL, Sivapragasam G, Samrot AV, Ali Khan MS, Farhana A, Alzahrani B, Tong J, Karuppiah T, Joseph NMS, Subbiah SK. Lipofection of Single Guide RNA Targeting Decreases Proliferation and Migration in Lung Adenocarcinoma Cells. Medicina (Kaunas, Lithuania). 57. PMID 34356991 DOI: 10.3390/medicina57070710   
2021 Wang C, Li S, Ademiloye AS, Nithiarasu P. Biomechanics of cells and subcellular components: A comprehensive review of computational models and applications. International Journal For Numerical Methods in Biomedical Engineering. e3520. PMID 34390323 DOI: 10.1002/cnm.3520   
2021 Adlung L, Stapor P, Tönsing C, Schmiester L, Schwarzmüller LE, Postawa L, Wang D, Timmer J, Klingmüller U, Hasenauer J, Schilling M. Cell-to-cell variability in JAK2/STAT5 pathway components and cytoplasmic volumes defines survival threshold in erythroid progenitor cells. Cell Reports. 36: 109507. PMID 34380040 DOI: 10.1016/j.celrep.2021.109507   
2021 Corselli M, Saksena S, Nakamoto M, Lomas WE, Taylor I, Chattopadhyay PK. Single cell multiomic analysis of T cell exhaustion in vitro. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. PMID 34390166 DOI: 10.1002/cyto.a.24496   
2021 Huang CW, Chen YC, Yin TC, Chen PJ, Chang TK, Su WC, Ma CJ, Li CC, Tsai HL, Wang JY. Low-Molecular-Weight Fucoidan as Complementary Therapy of Fluoropyrimidine-Based Chemotherapy in Colorectal Cancer. International Journal of Molecular Sciences. 22. PMID 34360807 DOI: 10.3390/ijms22158041   
2021 Kim HS, Shin YM, Chung S, Kim D, Park DB, Baek S, Park J, Kim SY, Kim DH, Yi SW, Lee S, Lee JB, Ko JY, Im GI, Kang ML, et al. Cell-Membrane-Derived Nanoparticles with Notch-1 Suppressor Delivery Promote Hypoxic Cell-Cell Packing and Inhibit Angiogenesis Acting as a Two-Edged Sword. Advanced Materials (Deerfield Beach, Fla.). e2101558. PMID 34431568 DOI: 10.1002/adma.202101558   
2021 Bode D, Cull AH, Rubio-Lara JA, Kent DG. Exploiting Single-Cell Tools in Gene and Cell Therapy. Frontiers in Immunology. 12: 702636. PMID 34322133 DOI: 10.3389/fimmu.2021.702636   
2021 Mo F, Yu Z, Li P, Oh J, Spolski R, Zhao L, Glassman CR, Yamamoto TN, Chen Y, Golebiowski FM, Hermans D, Majri-Morrison S, Picton LK, Liao W, Ren M, et al. An engineered IL-2 partial agonist promotes CD8 T cell stemness. Nature. PMID 34526724 DOI: 10.1038/s41586-021-03861-0   
2021 Wang J, Li H, Xu B. Biological functions of supramolecular assemblies of small molecules in cellular environment. Rsc Chemical Biology. 2: 289-305. PMID 34423303 DOI: 10.1039/d0cb00219d   
2021 Shi H, Wang M, Gong Y, Huang Y, Ning L, Xiang Y, Yin Y, Li G. Rapid Naked-Eye Tracking of On-Cell Phenotype Based on Dual-Aptamer-Weaved Cascade Assembly of Nanostructures. Analytical Chemistry. PMID 34347435 DOI: 10.1021/acs.analchem.1c01668   
2021 Zhang Z, Liu Q, Tan J, Zhan X, Liu T, Wang Y, Lu G, Wu M, Zhang Y. Coating with flexible DNA network enhanced T-cell activation and tumor killing for adoptive cell therapy. Acta Pharmaceutica Sinica. B. 11: 1965-1977. PMID 34386331 DOI: 10.1016/j.apsb.2021.04.002   
2021 Ma X, Somasundaram A, Qi Z, Hartman DJ, Singh H, Osmanbeyoglu HU. SPaRTAN, a computational framework for linking cell-surface receptors to transcriptional regulators. Nucleic Acids Research. PMID 34500467 DOI: 10.1093/nar/gkab745   
2021 Guo S, Huang C, Han F, Chen B, Ding Y, Zhao Y, Chen Z, Wen S, Wang M, Shen B, Zhu W. Gastric Cancer Mesenchymal Stem Cells Inhibit NK Cell Function through mTOR Signalling to Promote Tumour Growth. Stem Cells International. 2021: 9989790. PMID 34306099 DOI: 10.1155/2021/9989790   
2021 Guo S, Huang C, Han F, Chen B, Ding Y, Zhao Y, Chen Z, Wen S, Wang M, Shen B, Zhu W. Gastric Cancer Mesenchymal Stem Cells Inhibit NK Cell Function through mTOR Signalling to Promote Tumour Growth. Stem Cells International. 2021: 9989790. PMID 34306099 DOI: 10.1155/2021/9989790   
2021 Wang F, Zhang Y, Hao Y, Li X, Qi Y, Xin M, Xiao Q, Wang P. Characterizing the Metabolic and Immune Landscape of Non-small Cell Lung Cancer Reveals Prognostic Biomarkers Through Omics Data Integration. Frontiers in Cell and Developmental Biology. 9: 702112. PMID 34295900 DOI: 10.3389/fcell.2021.702112   
2021 Jacquelot N, Seillet C, Souza-Fonseca-Guimaraes F, Sacher AG, Belz GT, Ohashi PS. Natural Killer Cells and Type 1 Innate Lymphoid Cells in Hepatocellular Carcinoma: Current Knowledge and Future Perspectives. International Journal of Molecular Sciences. 22. PMID 34445750 DOI: 10.3390/ijms22169044   
2021 Elmentaite R, Kumasaka N, Roberts K, Fleming A, Dann E, King HW, Kleshchevnikov V, Dabrowska M, Pritchard S, Bolt L, Vieira SF, Mamanova L, Huang N, Perrone F, Goh Kai'En I, et al. Cells of the human intestinal tract mapped across space and time. Nature. 597: 250-255. PMID 34497389 DOI: 10.1038/s41586-021-03852-1   
2021 Miao Z, Humphreys BD, McMahon AP, Kim J. Multi-omics integration in the age of million single-cell data. Nature Reviews. Nephrology. PMID 34417589 DOI: 10.1038/s41581-021-00463-x   
2021 Rajasekaran S, Siddiqui J, Rakijas J, Nicolay B, Lin C, Khan E, Patel R, Morris R, Wyler E, Boukhali M, Balasubramanyam J, Ranjith Kumar R, Van Rechem C, Vogel C, Elchuri SV, et al. Integrated multi-omics analysis of RB-loss identifies widespread cellular programming and synthetic weaknesses. Communications Biology. 4: 977. PMID 34404904 DOI: 10.1038/s42003-021-02495-2   
2021 Maigne L, Delsol A, Fois G, Debiton E, Degoul F, Payno H. CPOP: An open source C++ cell POPulation modeler for radiation biology applications. Physica Medica : Pm : An International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (Aifb). 89: 41-50. PMID 34343765 DOI: 10.1016/j.ejmp.2021.07.016   
2021 Nagesh R, Kiran Kumar KM, Naveen Kumar M, Patil RH, Sharma SC. Regulation of Jun and Fos AP-1 transcription factors by JNK MAPKs signaling cascade in areca nut extract treated KB cells. Biochemistry and Biophysics Reports. 27: 101090. PMID 34401529 DOI: 10.1016/j.bbrep.2021.101090   
2021 Cable J, Pourquié O, Wellen KE, Finley LWS, Aulehla A, Gould AP, Teleman A, Tu WB, Garrett WS, Miguel-Aliaga I, Perrimon N, Hooper LV, Walhout AJM, Wei W, Alexandrov T, et al. Metabolic decisions in development and disease-a Keystone Symposia report. Annals of the New York Academy of Sciences. PMID 34414571 DOI: 10.1111/nyas.14678   
2021 Cetin AE, Topkaya SN, Yalcin-Ozuysal O, Khademhosseini A. Refractive Index Sensing for Measuring Single Cell Growth. Acs Nano. 15: 10710-10721. PMID 34029478 DOI: 10.1021/acsnano.1c04031   
2021 Nong S, Wang Z, Wei Z, Ma L, Guan Y, Ni J. HN1L promotes stem cell-like properties by regulating TGF-β signaling pathway through targeting FOXP2 in prostate cancer. Cell Biology International. PMID 34519127 DOI: 10.1002/cbin.11701   
2021 Balogh P, Gounley J, Roychowdhury S, Randles A. A data-driven approach to modeling cancer cell mechanics during microcirculatory transport. Scientific Reports. 11: 15232. PMID 34315934 DOI: 10.1038/s41598-021-94445-5   
2021 Brian Iv BF, Freedman TS. The Src-family kinase Lyn in immunoreceptor signaling. Endocrinology. PMID 34320188 DOI: 10.1210/endocr/bqab152   
2021 Li Y, Li J, Yuan Q, Bian X, Long F, Duan R, Gao F, Gao S, Wei S, Wang A, Liu A, Li X, Sun W, Liu Q. Deficiency in WDFY4 reduces the number of CD8 T cells via reactive oxygen species-induced apoptosis. Molecular Immunology. 139: 131-138. PMID 34482201 DOI: 10.1016/j.molimm.2021.08.022   
2021 Bai D, Peng J, Yi C. Advances in single-cell multi-omics profiling. Rsc Chemical Biology. 2: 441-449. PMID 34458793 DOI: 10.1039/d0cb00163e   
2021 Lawson-Keister E, Manning ML. Jamming and arrest of cell motion in biological tissues. Current Opinion in Cell Biology. 72: 146-155. PMID 34461581 DOI: 10.1016/   
2021 Wong HS, Germain RN. Mesoscale T cell antigen discrimination emerges from intercellular feedback. Trends in Immunology. PMID 34493455 DOI: 10.1016/   
2021 Osman A, Yan B, Li Y, Pavelko KD, Quandt J, Saadalla A, Singh MP, Kazemian M, Gounari F, Khazaie K. TCF-1 controls T cell functions that regulate inflammation, CD8 T cell cytotoxicity and severity of colon cancer. Nature Immunology. PMID 34385712 DOI: 10.1038/s41590-021-00987-1   
2021 van der Leun AM, Hoekstra ME, Reinalda L, Scheele CLGJ, Toebes M, van de Graaff MJ, Chen LYY, Li H, Bercovich A, Lubling Y, David E, Thommen DS, Tanay A, van Rheenen J, Amit I, et al. Single-cell analysis of regions of interest (SCARI) using a photosensitive tag. Nature Chemical Biology. PMID 34504322 DOI: 10.1038/s41589-021-00839-x   
2021 Sai C, Qin W, Meng J, Gao LN, Huang L, Zhang Z, Wang H, Chen H, Yan C. Macleayins A From Promotes Cell Apoptosis Through Wnt/β-Catenin Signaling Pathway and Inhibits Proliferation, Migration, and Invasion in Cervical Cancer HeLa Cells. Frontiers in Pharmacology. 12: 668348. PMID 34421589 DOI: 10.3389/fphar.2021.668348   
2021 Sajith AM, Narasimhamurthy KH, Shanmugam MK, Rangappa S, Chandra Nayak S, Chinnathambi A, Awad Alahmadi T, Ali Alharbi S, Haridas KR, Reddy EK, Savitha B, Dhananjaya Mohan C, Rangappa KS. Pyrimidine-2,4-dione Targets STAT3 Signaling Pathway to Induce Cytotoxicity in Hepatocellular Carcinoma Cells. Bioorganic & Medicinal Chemistry Letters. 128332. PMID 34418571 DOI: 10.1016/j.bmcl.2021.128332   
2021 Boonyanugomol W, Rukseree K, Prapatpong P, Reamtong O, Baik SC, Jung M, Shin MK, Kang HL, Lee WK. An In Vitro Anti-Cancer Activity of Essential Oil by Inducing Apoptosis in Human Gastric Cancer Cell Line. Medicina (Kaunas, Lithuania). 57. PMID 34440988 DOI: 10.3390/medicina57080784   
2021 Karimnia N, Wilson AL, Green E, Matthews A, Jobling TW, Plebanski M, Bilandzic M, Stephens AN. Chemoresistance is mediated by ovarian cancer leader cells in vitro. Journal of Experimental & Clinical Cancer Research : Cr. 40: 276. PMID 34470672 DOI: 10.1186/s13046-021-02086-3   
2021 Janelle V, Neault M, Lebel MÈ, De Sousa DM, Boulet S, Durrieu L, Carli C, Muzac C, Lemieux S, Labrecque N, Melichar HJ, Mallette FA, Delisle JS. p16 Regulates Cellular Senescence in PD-1-Expressing Human T Cells. Frontiers in Immunology. 12: 698565. PMID 34434190 DOI: 10.3389/fimmu.2021.698565   
2021 Halder D, Mallick D, Chatterjee A, Jana SS. Nonmuscle Myosin II in cancer cell migration and mechanotransduction. The International Journal of Biochemistry & Cell Biology. 106058. PMID 34400319 DOI: 10.1016/j.biocel.2021.106058   
2021 Geuenich MJ, Hou J, Lee S, Ayub S, Jackson HW, Campbell KR. Automated assignment of cell identity from single-cell multiplexed imaging and proteomic data. Cell Systems. PMID 34536381 DOI: 10.1016/j.cels.2021.08.012   
2021 Mahant S, Chakraborty A, Som A, Mehra S, Das K, Mukhopadhyay AK, Gehlot V, Bose S, Das R. The Synergistic Role of Tip α, Nucleolin and Ras in Helicobacter pylori Infection Regulates the Cell Fate Towards Inflammation or Apoptosis. Current Microbiology. PMID 34468852 DOI: 10.1007/s00284-021-02626-2   
2021 Lee SY, Teng Y, Son M, Ku B, Hwang HJ, Tergaonkar V, Chow PK, Lee DW, Nam DH. Three-Dimensional Aggregated Spheroid Model of Hepatocellular Carcinoma Using a 96-Pillar/Well Plate. Molecules (Basel, Switzerland). 26. PMID 34443536 DOI: 10.3390/molecules26164949   
2021 Gaudette BT, Roman CJ, Ochoa TA, Gómez Atria D, Jones DD, Siebel CW, Maillard I, Allman D. Resting innate-like B cells leverage sustained Notch2/mTORC1 signaling to achieve rapid and mitosis-independent plasma cell differentiation. The Journal of Clinical Investigation. PMID 34473651 DOI: 10.1172/JCI151975   
2021 Cherry C, Maestas DR, Han J, Andorko JI, Cahan P, Fertig EJ, Garmire LX, Elisseeff JH. Computational reconstruction of the signalling networks surrounding implanted biomaterials from single-cell transcriptomics. Nature Biomedical Engineering. PMID 34341534 DOI: 10.1038/s41551-021-00770-5   
2021 Li H, Gao Y, Xie L, Wang R, Duan R, Li Z, Chen B, Zhu L, Wang X, Su W. Prednisone Reprograms the Transcriptional Immune Cell Landscape in CNS Autoimmune Disease. Frontiers in Immunology. 12: 739605. PMID 34484247 DOI: 10.3389/fimmu.2021.739605