Jun O. Liu - Publications

Affiliations: 
Pharmacology and Molecular Sciences Johns Hopkins University School of Medicine, Baltimore, MD, United States 
Website:
http://www.hopkinsmedicine.org/profiles/results/directory/profile/0800038/jun-liu

364 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Fang H, Wang X, Damarla M, Sun R, He Q, Li R, Luo P, Liu JO, Xia Z. Dimethyl Fumarate Protects against Lipopolysaccharide- (LPS-) Induced Sepsis through Inhibition of NF-B Pathway in Mice. Mediators of Inflammation. 2023: 5133505. PMID 37840694 DOI: 10.1155/2023/5133505  0.776
2023 Reyes Gaido OE, Pavlaki N, Granger JM, Mesubi OO, Liu B, Lin BL, Long A, Walker D, Mayourian J, Schole KL, Terrillion CE, Nkashama LJ, Hulsurkar MM, Dorn LE, Ferrero KM, ... ... Liu JO, et al. An improved reporter identifies ruxolitinib as a potent and cardioprotective CaMKII inhibitor. Science Translational Medicine. 15: eabq7839. PMID 37343080 DOI: 10.1126/scitranslmed.abq7839  0.712
2023 Qian S, Head SA, Sanchez PR, Liu JO, Jin Z. Synthesis and biological evaluation of biotinylated ZJ-101. Bioorganic & Medicinal Chemistry Letters. 91: 129372. PMID 37301523 DOI: 10.1016/j.bmcl.2023.129372  0.796
2023 Sanchez PR, Head SA, Qian S, Qiu H, Roy A, Jin Z, Zheng W, Liu JO. Modulation of the Endomembrane System by the Anticancer Natural Product Superstolide/ZJ-101. International Journal of Molecular Sciences. 24. PMID 37298526 DOI: 10.3390/ijms24119575  0.811
2023 Liu J, Zhang W, Wu S, Zeng T, Luo F, Jiang Q, Yang R. A clinical case report of Balamuthia granulomatous amoebic encephalitis in a non-immunocompromised patient and literature review. Bmc Infectious Diseases. 23: 245. PMID 37072710 DOI: 10.1186/s12879-023-08228-6  0.309
2023 Sun H, Zhu G, Ling S, Liu J, Xu JW. 4'‑O‑methylbavachalcone inhibits succinate induced cardiomyocyte hypertrophy via the NFATc4 pathway. Experimental and Therapeutic Medicine. 25: 172. PMID 37006873 DOI: 10.3892/etm.2023.11871  0.302
2023 Xu XL, Lan JX, Huang H, Dai W, Peng XP, Liu SL, Chen WM, Huang LJ, Liu J, Li XJ, Zeng JL, Huang XH, Zhao GN, Hou W. Synthesis, biological activity and mechanism of action of novel allosecurinine derivatives as potential antitumor agents. Bioorganic & Medicinal Chemistry. 82: 117234. PMID 36906964 DOI: 10.1016/j.bmc.2023.117234  0.344
2023 Zhang Y, Yu Y, Liu X, Miao J, Han Y, Liu J, Wang L. An n-type All-Fused-Ring Molecule with Photoresponse to 1000 nm for Highly Sensitive Near Infrared Photodetector. Advanced Materials (Deerfield Beach, Fla.). e2211714. PMID 36842062 DOI: 10.1002/adma.202211714  0.307
2023 Wang K, Yu Y, Wang W, Jiang Y, Li Y, Jiang X, Qiao Y, Chen L, Zhao X, Liu J, Yang A, Li J, Zhang R. Targeting the E3 ligase NEDD4 as a novel therapeutic strategy for IGF1 signal pathway-driven gastric cancer. Oncogene. PMID 36774408 DOI: 10.1038/s41388-023-02619-4  0.307
2023 Sang W, Liu J, Xing Y, Feng C, Hu Q, Lang Y, Li X, Bao J, Jiang H. Transcriptome analysis of hepatopancreas of Chinese grass shrimp, Palaemonetes sinensis, infected by Enterocytospora artemiae. Fish & Shellfish Immunology. 108557. PMID 36669602 DOI: 10.1016/j.fsi.2023.108557  0.338
2022 Hu RJ, Chen XC, Xu L, Rui XH, Wan L, Lu J, Liu J, Pei H. MiR-181a-5p Delivered by Adipose-Derived Mesenchymal Stem Cell Exosomes Alleviates pneumonia Infection-Induced Lung Injury by Targeting STAT3 Signaling. Mediators of Inflammation. 2022: 5188895. PMID 36570020 DOI: 10.1155/2022/5188895  0.47
2022 Xu Z, Jia Y, Liu J, Ren X, Yang X, Xia X, Pan X. Naringenin and Quercetin Exert Contradictory Cytoprotective and Cytotoxic Effects on Tamoxifen-Induced Apoptosis in HepG2 Cells. Nutrients. 14. PMID 36558554 DOI: 10.3390/nu14245394  0.324
2022 Zhou X, Kang Y, Chang Y, Xia S, Wu M, Liu J, Dong D, Zhang W, Chen H, Li H. CRC Therapy Identifies Indian Hedgehog Signaling in Mouse Endometrial Epithelial Cells and Inhibition of Ihh-KLF9 as a Novel Strategy for Treating IUA. Cells. 11. PMID 36552817 DOI: 10.3390/cells11244053  0.325
2022 Liu J, Chen X, Xu L, Tu F, Rui X, Zhang L, Yan Z, Liu Y, Hu R. Neutrophil membrane-coated nanoparticles exhibit increased antimicrobial activities in an anti-microbial resistant K. pneumonia infection model. Nanomedicine : Nanotechnology, Biology, and Medicine. 48: 102640. PMID 36549558 DOI: 10.1016/j.nano.2022.102640  0.449
2022 Campbell LE, Anderson AM, Chen Y, Johnson SM, McMahon CE, Liu J. Identification of lipid droplet targeting motifs and mechanisms for lipolytic inhibitors G0S2 and HIG2. Journal of Cell Science. PMID 36420951 DOI: 10.1242/jcs.260236  0.306
2022 Li H, Zhong D, Luo H, Shi W, Xie S, Qiang H, Zhu L, Gao L, Liu J, Sun S, Ding Z, Yang X, Lu X. Nanobody-based CAR T cells targeting intracellular tumor antigens. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 156: 113919. PMID 36411612 DOI: 10.1016/j.biopha.2022.113919  0.337
2022 Liu Y, Tian S, Yi B, Feng Z, Chu T, Liu J, Zhang C, Zhang S, Wang Y. Platycodin D sensitizes -mutant colorectal cancer cells to cetuximab by inhibiting the PI3K/Akt signaling pathway. Frontiers in Oncology. 12: 1046143. PMID 36387129 DOI: 10.3389/fonc.2022.1046143  0.321
2022 Zhou M, Xu D, Zhang W, Wang Y, Zuo M, Wang S, Liu T, Zhang J, Yin L, Guo Z, Liu J, Tan J. The hepato-cardiac disorders in Tibetan residents with hepatic echinococcosis: A case-control echocardiography study. Journal of Clinical Ultrasound : Jcu. 50: 1251-1259. PMID 36353905 DOI: 10.1002/jcu.23287  0.304
2022 Park E, Lee C, Park J, Liu J, Hong J, Shin DY, Byun JM, Yun H, Koh Y, Yoon SS. Mitigating the BFL1-mediated antiapoptotic pathway in diffuse large B cell lymphoma by inhibiting HDACs. Leukemia & Lymphoma. 1-12. PMID 36331521 DOI: 10.1080/10428194.2022.2140282  0.311
2022 Jiang L, Liu J. Prefoldin 6 promotes glioma progression via the AKT signalling pathway. Cell Biology International. PMID 36300673 DOI: 10.1002/cbin.11895  0.302
2022 Tian Z, Sun C, Liu J. Pelargonidin inhibits vascularization and metastasis of brain gliomas by blocking the PI3K/AKT/mTOR pathway. Journal of Biosciences. 47. PMID 36226369  0.335
2022 Truax NJ, Ayinde S, Liu JO, Romo D. Total Synthesis of Rameswaralide Utilizing a Pharmacophore-Directed Retrosynthetic Strategy. Journal of the American Chemical Society. PMID 36166374 DOI: 10.1021/jacs.2c08245  0.533
2022 Wang C, Liu J, Lei H, Li Y, Wu J, Guo B, Hu R, Liu T, Wu J, Ding Y, Hu C, Liang S, Xiao C, Liang X, Huang D, et al. Clinical characteristics and outcomes of newly diagnosed patients with HIV-associated aggressive B-cell NHL in China. Journal of Cellular and Molecular Medicine. PMID 36056692 DOI: 10.1111/jcmm.17534  0.327
2022 Mu XR, Ma MM, Lu ZY, Liu J, Xue YT, Cao J, Zeng LY, Li F, Xu KL, Wu QY. Effects of the PLK4 inhibitor Centrinone on the biological behaviors of acute myeloid leukemia cell lines. Frontiers in Genetics. 13: 898474. PMID 36051696 DOI: 10.3389/fgene.2022.898474  0.301
2022 Zhao Y, Lin K, Zhang H, Yuan G, Zhang Y, Pan J, Hong L, Huang Y, Ye Y, Huang L, Chen X, Liu J, Li X, He X, Yue Q, et al. Evaluation of droplet digital PCR rapid detection method and precise diagnosis and treatment for suspected sepsis (PROGRESS): a study protocol for a multi-center pragmatic randomized controlled trial. Bmc Infectious Diseases. 22: 630. PMID 35854212 DOI: 10.1186/s12879-022-07557-2  0.322
2022 Park H, Kam TI, Peng H, Chou SC, Mehrabani-Tabari AA, Song JJ, Yin X, Karuppagounder SS, Umanah GK, Rao AVS, Choi Y, Aggarwal A, Chang S, Kim H, Byun J, ... Liu JO, et al. PAAN/MIF nuclease inhibition prevents neurodegeneration in Parkinson's disease. Cell. PMID 35545089 DOI: 10.1016/j.cell.2022.04.020  0.768
2022 Zhang MH, Liu J. Cleavage stimulation factor 2 promotes malignant progression of liver hepatocellular carcinoma by activating phosphatidylinositol 3'-kinase/protein kinase B/mammalian target of rapamycin pathway. Bioengineered. 13: 10047-10060. PMID 35412944 DOI: 10.1080/21655979.2022.2063100  0.308
2022 Chen W, Qie C, Hu X, Wang L, Jiang J, Liu W, Liu J. A small molecule inhibitor of VSIG-8 prevents its binding to VISTA. Investigational New Drugs. PMID 35404016 DOI: 10.1007/s10637-022-01244-4  0.346
2022 Wang L, Zhang X, Liu J, Liu Q. MUC21 induces the viability and migration of glioblastoma via the STAT3/AKT pathway. Experimental and Therapeutic Medicine. 23: 331. PMID 35401801 DOI: 10.3892/etm.2022.11260  0.301
2022 Wang K, Liu J, Li YL, Li JP, Zhang R. Ubiquitination/de-ubiquitination: A promising therapeutic target for PTEN reactivation in cancer. Biochimica Et Biophysica Acta. Reviews On Cancer. 1877: 188723. PMID 35314212 DOI: 10.1016/j.bbcan.2022.188723  0.304
2022 Zhang S, Liu J, Li F, Yang M, Wang J. EZH2 suppresses insulinoma development by epigenetically reducing KIF4A expression via H3K27me3 modification. Gene. 146317. PMID 35182680 DOI: 10.1016/j.gene.2022.146317  0.301
2022 Chen BX, Fu H, Gao JD, Zhang YX, Huang WJ, Chen ZJ, Qi-Zhang, Yan SJ, Liu J. Identification of Metabolomic Biomarkers of Seed Vigor and Aging in Hybrid Rice. Rice (New York, N.Y.). 15: 7. PMID 35084595 DOI: 10.1186/s12284-022-00552-w  0.407
2021 Wang Y, Peng H, Guo Z, Ullman BR, Yamamoto K, Hong SY, Liu JO. Influence of stereochemistry on the activity of rapadocin, an isoform-specific inhibitor of the nucleoside transporter ENT1. Chemical Science. 12: 11484-11489. PMID 34667552 DOI: 10.1039/d1sc02295d  0.814
2021 Young DJ, Nguyen B, Li L, Higashimoto T, Levis MJ, Liu JO, Small D. A method for overcoming plasma protein inhibition of tyrosine kinase inhibitors. Blood Cancer Discovery. 2: 532-547. PMID 34589716 DOI: 10.1158/2643-3230.bcd-20-0119  0.33
2021 Ju R, Chen X, Zhang S, Liu B, Pei H, Tu F, Liu J, Yu H. Plasma exosome-derived fragile-site associated tumor suppressor is a powerful predictor of prognosis in patients with ovarian cancer. Bosnian Journal of Basic Medical Sciences. PMID 34491890 DOI: 10.17305/bjbms.2021.6404  0.459
2021 Yan Y, Narayan A, Cho S, Cheng Z, Liu JO, Zhu H, Wang G, Wharram B, Lisok A, Brummet M, Saeki H, Huang T, Gabrielson K, Gabrielson E, Cope L, et al. CRYβB2 enhances tumorigenesis through upregulation of nucleolin in triple negative breast cancer. Oncogene. PMID 34341513 DOI: 10.1038/s41388-021-01975-3  0.528
2021 Zhang L, Chen C, Fu J, Lilley B, Berlinicke C, Hansen B, Ding D, Wang G, Wang T, Shou D, Ye Y, Mulligan T, Emmerich K, Saxena MT, Hall KR, ... ... Liu JO, et al. Large-scale phenotypic drug screen identifies neuroprotectants in zebrafish and mouse models of retinitis pigmentosa. Elife. 10. PMID 34184634 DOI: 10.7554/eLife.57245  0.562
2021 Tian S, Zheng Y, Xiao S, Luo P, Sun R, Liu J, Xia Z. Ivermectin inhibits cell proliferation and the expression levels of type I collagen, α‑SMA and CCN2 in hypertrophic scar fibroblasts. Molecular Medicine Reports. 24. PMID 33955514 DOI: 10.3892/mmr.2021.12127  0.35
2021 Hao C, Guo R, Liu J, Hu X, Guo J, Yao Y, Zhao Z, Qi Z, Yin J, Chen L, Wang H, Xu B, Li W. Exome sequencing as the first-tier test for pediatric respiratory diseases: a single-center study. Human Mutation. PMID 33942430 DOI: 10.1002/humu.24216  0.35
2021 Shi X, Jiang L, Zhao X, Chen B, Shi W, Cao Y, Chen Y, Li X, He Y, Li C, Liu X, Li X, Lu H, Chen C, Liu J. Adipose-Derived Stromal Cell-Sheets Sandwiched, Book-Shaped Acellular Dermal Matrix Capable of Sustained Release of Basic Fibroblast Growth Factor Promote Diabetic Wound Healing. Frontiers in Cell and Developmental Biology. 9: 646967. PMID 33842472 DOI: 10.3389/fcell.2021.646967  0.337
2021 Xie X, Chen C, Chen W, Jiang J, Wang L, Li T, Sun H, Liu J. Structural Basis of VSIG3: The Ligand for VISTA. Frontiers in Immunology. 12: 625808. PMID 33841409 DOI: 10.3389/fimmu.2021.625808  0.333
2021 Wang H, Tang H, Fang Y, Tan L, Yin J, Shen Y, Zeng Z, Zhu J, Hou Y, Du M, Jiao J, Jiang H, Gong L, Li Z, Liu J, et al. Morbidity and Mortality of Patients Who Underwent Minimally Invasive Esophagectomy After Neoadjuvant Chemoradiotherapy vs Neoadjuvant Chemotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma: A Randomized Clinical Trial. Jama Surgery. PMID 33729467 DOI: 10.1001/jamasurg.2021.0133  0.311
2021 Wan L, Chen X, Deng J, Zhang S, Tu F, Pei H, Hu R, Liu J, Yu H. Plasma exosome-derived B-cell translation gene 1: a predictive marker for the prognosis in patients with non-small cell lung cancer. Journal of Cancer. 12: 1538-1547. PMID 33531999 DOI: 10.7150/jca.52320  0.461
2020 Zhuang Q, Li F, Liu J, Wang H, Tian Y, Zhang Z, Wang F, Zhao Z, Chen J, Wu H. Nuclear exclusion of YAP exacerbates podocyte apoptosis and disease progression in Adriamycin-induced focal segmental glomerulosclerosis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 258-270. PMID 33203894 DOI: 10.1038/s41374-020-00503-3  0.634
2020 Zhuang Q, Li F, Liu J, Wang H, Tian Y, Zhang Z, Wang F, Zhao Z, Chen J, Wu H. Nuclear exclusion of YAP exacerbates podocyte apoptosis and disease progression in Adriamycin-induced focal segmental glomerulosclerosis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 258-270. PMID 33203894 DOI: 10.1038/s41374-020-00503-3  0.634
2020 Zhuang Q, Li F, Liu J, Wang H, Tian Y, Zhang Z, Wang F, Zhao Z, Chen J, Wu H. Nuclear exclusion of YAP exacerbates podocyte apoptosis and disease progression in Adriamycin-induced focal segmental glomerulosclerosis. Laboratory Investigation; a Journal of Technical Methods and Pathology. 101: 258-270. PMID 33203894 DOI: 10.1038/s41374-020-00503-3  0.634
2020 Tong L, Zhao Q, Datan E, Lin GQ, Minn I, Pomper MG, Yu B, Romo D, He QL, Liu JO. Triptolide: reflections on two decades of research and prospects for the future. Natural Product Reports. PMID 33146205 DOI: 10.1039/d0np00054j  0.782
2020 Liu J, Li L, Li X, Wang X, Zhao X, Qiao Y, Xu Y, Sun Y, Qian L, Liu Z, Ji A, Lou H. Discovery of lysosome-targeted covalent anticancer agents based on isosteviol skeleton. European Journal of Medicinal Chemistry. 112896. PMID 33097300 DOI: 10.1016/j.ejmech.2020.112896  0.331
2020 Datan E, Minn I, Xu P, He QL, Ahn HH, Yu B, Pomper MG, Liu JO. A Glucose-Triptolide Conjugate Selectively Targets Cancer Cells under Hypoxia. Iscience. 23: 101536. PMID 33083765 DOI: 10.1016/J.Isci.2020.101536  0.81
2020 Dai Y, Hartke R, Li C, Yang Q, Liu JO, Wang LX. Synthetic Fluorinated L-Fucose Analogs Inhibit Proliferation of Cancer Cells and Primary Endothelial Cells. Acs Chemical Biology. PMID 32930566 DOI: 10.1021/Acschembio.0C00228  0.804
2020 Lu L, Jiang J, Zhan M, Zhang H, Wang QT, Sun SN, Guo XK, Yin H, Wei Y, Li SY, Liu JO, Li Y, He YW. Targeting Tumor-Associated Antigens in Hepatocellular Carcinoma for Immunotherapy: Past Pitfalls and Future Strategies. Hepatology (Baltimore, Md.). PMID 32767586 DOI: 10.1002/Hep.31502  0.306
2020 Li Z, Tan J, Liu X, Zhang W, Meng Q, Zhou M, Lin N, Cao F, Lu J, Liu J, Yin L. Tibetan patients with hepatic hydatidosis can tolerate hypoxic environment without incident increase of pulmonary hypertension: an echocardiography study. The International Journal of Cardiovascular Imaging. PMID 32767023 DOI: 10.1007/s10554-020-01922-5  0.302
2020 Hurwitz LM, Kulac I, Gumuskaya B, Baena Del Valle JA, Benedetti I, Pan F, Liu JO, Marrone MT, Arnold KB, Goodman PJ, Tangen CM, Lucia MS, Thompson IM, Drake CG, Isaacs WB, et al. Use of Aspirin and Statins in Relation to Inflammation in Benign Prostate Tissue in the Placebo Arm of the Prostate Cancer Prevention Trial. Cancer Prevention Research (Philadelphia, Pa.). PMID 32581009 DOI: 10.1158/1940-6207.Capr-19-0450  0.554
2020 Li Y, Pasunooti KK, Peng H, Li RJ, Shi WQ, Liu W, Cheng Z, Head SA, Liu JO. Design and Synthesis of Tetrazole- and Pyridine-Containing Itraconazole Analogs as Potent Angiogenesis Inhibitors. Acs Medicinal Chemistry Letters. 11: 1111-1117. PMID 32550989 DOI: 10.1021/Acsmedchemlett.9B00438  0.821
2020 Li M, Liu S, Chen H, Zhou X, Zhou J, Zhou S, Yuan H, Xu QL, Liu J, Cheng K, Sun H, Wang Y, Chen C, Wen X. N-benzylpiperidinol derivatives as novel USP7 inhibitors: Structure-activity relationships and X-ray crystallographic studies. European Journal of Medicinal Chemistry. 199: 112279. PMID 32497973 DOI: 10.1016/j.ejmech.2020.112279  0.308
2020 Liu J, Cao C. Evaluation of a GSH-targeting prodrug via a sulfonamide-induced "integrative" platform for selective cancer therapy. The Analyst. PMID 32478783 DOI: 10.1039/d0an00627k  0.306
2020 Ma X, Claus LAN, Leslie ME, Tao K, Wu Z, Liu J, Yu X, Li B, Zhou J, Savatin DV, Peng J, Tyler BM, Heese A, Russinova E, He P, et al. Ligand-induced monoubiquitination of BIK1 regulates plant immunity. Nature. 581: 199-203. PMID 32404997 DOI: 10.1038/S41586-020-2210-3  0.304
2020 Cui Z, Liu Y, Wan W, Xu Y, Hu Y, Ding M, Dou X, Wang R, Li H, Meng Y, Li W, Jiang W, Li Z, Li Y, Tan M, ... ... Liu JO, et al. Ethacrynic acid targets GSTM1 to ameliorate obesity by promoting browning of white adipocytes. Protein & Cell. PMID 32399897 DOI: 10.1007/S13238-020-00717-7  0.607
2020 Lu L, Jiang J, Zhan M, Zhang H, Wang QT, Sun SN, Guo XK, Yin H, Wei Y, Liu JO, Li SY, Li Y, He YW. Targeting Neoantigens in Hepatocellular Carcinoma for Immunotherapy: A Futile Strategy? Hepatology (Baltimore, Md.). PMID 32299136 DOI: 10.1002/Hep.31279  0.331
2019 Liberti MV, Allen AE, Ramesh V, Dai Z, Singleton KR, Guo Z, Liu JO, Wood KC, Locasale JW. Evolved resistance to partial GAPDH inhibition results in loss of the Warburg effect and in a different state of glycolysis. The Journal of Biological Chemistry. PMID 31748414 DOI: 10.1074/Jbc.Ra119.010903  0.724
2019 Liu JO, Guo Z, Cheng Z, Wang J, Liu W, Peng H, Wang Y, Rao S, Li R, Ying X, Korangath P, Liberti M, Li Y, Xie Y, Hong S, et al. Discovery of a potent GLUT inhibitor using rapafucin 3D microarrays. Angewandte Chemie (International Ed. in English). PMID 31591797 DOI: 10.1002/Anie.201905578  0.81
2019 Wang Y, Peiffer BJ, Su Q, Liu JO. One-step Heck Reaction Generates Nonimmunosuppressive FK506 Analogs for Pharmacological BMP Activation. Acs Medicinal Chemistry Letters. 10: 1279-1283. PMID 31531197 DOI: 10.1021/Acsmedchemlett.9B00144  0.799
2019 Truax NJ, Ayinde S, Van K, Liu JO, Romo D. Pharmacophore-Directed Retrosynthesis Applied to Rameswaralide: Synthesis and Bioactivity of Natural Product Tricyclic Cores. Organic Letters. PMID 31498642 DOI: 10.1021/Acs.Orglett.9B02713  0.778
2019 Liu J, Liu Y, Liu Y, Huang L, Wang G, Wang J, Xu X, Shi C, Huang J. Anticancer Action of Psilostachyin-A in 5-Fluorouracil-Resistant Human Liver Carcinoma are Mediated Through Autophagy Induction, G2/M Phase Cell Cycle Arrest and Inhibiting Extracellular-Signal-Regulated Kinase/Mitogen Activated Protein Kinase (ERK/MAPK) Signaling Pathway. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research. 25: 6711-6718. PMID 31492830 DOI: 10.12659/MSM.916635  0.307
2019 Liu J, Liu F, Bao R, Jiang K, Khan F, Li Z, Peng H, Chen J, Alodhayb A, Thundat T. Scaled-up direct-current generation in MoS multilayers-based moving heterojunctions. Acs Applied Materials & Interfaces. PMID 31476860 DOI: 10.1021/acsami.9b09851  0.409
2019 Kim IS, Gao Y, Welte T, Wang H, Liu J, Janghorban M, Sheng K, Niu Y, Goldstein A, Zhao N, Bado I, Lo HC, Toneff MJ, Nguyen T, Bu W, et al. Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms. Nature Cell Biology. PMID 31451770 DOI: 10.1038/S41556-019-0373-7  0.342
2019 Zeng Q, Liu YM, Liu J, Han J, Guo JX, Lu S, Huang XM, Yi P, Lang JY, Zhang P, Wang CT. Inhibition of ZIP4 reverses epithelial-to-mesenchymal transition and enhances the radiosensitivity in human nasopharyngeal carcinoma cells. Cell Death & Disease. 10: 588. PMID 31383854 DOI: 10.1038/s41419-019-1807-7  0.3
2019 Lee J, Kosowicz JG, Hayward SD, Desai P, Stone J, Lee JM, Liu JO, Ambinder RF. Pharmacologic Activation of Lytic Epstein-Barr Virus Gene Expression Without Virion Production. Journal of Virology. PMID 31341058 DOI: 10.1128/Jvi.00998-19  0.366
2019 Liu S, Fu H, Jiang J, Chen Z, Gao J, Shu H, Zhang S, Yang C, Liu J. Overexpression of a CPYC-Type Glutaredoxin, , Causes Abnormal Embryos and an Increased Grain Weight in Rice. Frontiers in Plant Science. 10: 848. PMID 31316541 DOI: 10.3389/fpls.2019.00848  0.416
2019 Chen BX, Peng YX, Gao JD, Zhang Q, Liu QJ, Fu H, Liu J. Coumarin-Induced Delay of Rice Seed Germination Is Mediated by Suppression of Abscisic Acid Catabolism and Reactive Oxygen Species Production. Frontiers in Plant Science. 10: 828. PMID 31316534 DOI: 10.3389/fpls.2019.00828  0.433
2019 Zhao ZY, Xie XJ, Li WH, Liu J, Chen Z, Zhang B, Li T, Li SL, Lu JG, Zhang L, Zhang LH, Xu Z, Lee HC, Zhao YJ. A Cell-Permeant Mimetic of NMN Activates SARM1 to Produce Cyclic ADP-Ribose and Induce Non-apoptotic Cell Death. Iscience. 15: 452-466. PMID 31128467 DOI: 10.1016/J.Isci.2019.05.001  0.397
2019 Li Y, Zhang X, Yang X, Liu J, Li L, Ma W, Chen M. Differential effects of ginkgol C17:1 on cisplatin-induced cytotoxicity: Protecting human normal L02 hepatocytes versus sensitizing human hepatoma HepG2 cells. Oncology Letters. 17: 3181-3190. PMID 30867748 DOI: 10.3892/ol.2019.9974  0.309
2019 Peiffer BJ, Qi L, Ahmadi AR, Wang Y, Guo Z, Peng H, Sun Z, Liu JO. Activation of BMP Signaling by FKBP12 Ligands Synergizes with Inhibition of CXCR4 to Accelerate Wound Healing. Cell Chemical Biology. PMID 30827938 DOI: 10.1016/J.Chembiol.2019.01.011  0.787
2018 Guo Z, Hong SY, Wang J, Rehan S, Liu W, Peng H, Das M, Li W, Bhat S, Peiffer B, Ullman BR, Tse CM, Tarmakova Z, Schiene-Fischer C, Fischer G, ... ... Liu JO, et al. Rapamycin-inspired macrocycles with new target specificity. Nature Chemistry. PMID 30532015 DOI: 10.1038/S41557-018-0187-4  0.801
2018 Yuan L, Liu J, He W, Bao Y, Sheng L, Zou C, Hu B, Ge W, Liu Y, Wang J, Lin B, Li Y, Ma E. Discovery of a novel cathepsin inhibitor with dual autophagy-inducing and metastasis-inhibiting effects on breast cancer cells. Bioorganic Chemistry. 84: 239-253. PMID 30503850 DOI: 10.1016/j.bioorg.2018.11.025  0.322
2018 Li Y, Pasunooti KK, Li RJ, Liu W, Head SA, Shi WQ, Liu JO. Novel Tetrazole-containing Analogs of Itraconazole as Potent Anti-angiogenic Agents with Reduced CYP3A4 Inhibition. Journal of Medicinal Chemistry. PMID 30481027 DOI: 10.1021/Acs.Jmedchem.8B01252  0.826
2018 Li D, Liu J, Wang X, Kong D, Du W, Li H, Hse CY, Shupe T, Zhou D, Zhao K. Biological Potential and Mechanism of Prodigiosin from Subsp. in Human Choriocarcinoma and Prostate Cancer Cell Lines. International Journal of Molecular Sciences. 19. PMID 30400387 DOI: 10.3390/ijms19113465  0.314
2018 Chen M, Yan R, Zhou K, Li X, Zhang Y, Liu C, Jiang M, Ye H, Meng X, Pang N, Zhao L, Liu J, Xiao W, Hu R, Cui Q, et al. Akt-mediated platelet apoptosis and its therapeutic implications in immune thrombocytopenia. Proceedings of the National Academy of Sciences of the United States of America. PMID 30337485 DOI: 10.1182/Blood-2018-99-114952  0.361
2018 Yuan L, Sheng L, He W, Zou C, Hu B, Liu J, Ge W, Liu Y, Wang J, Ma E. Discovery of novel cathepsin inhibitors with potent anti-metastatic effects in breast cancer cells. Bioorganic Chemistry. 81: 672-680. PMID 30253340 DOI: 10.1016/j.bioorg.2018.09.029  0.345
2018 Jiang P, Gu S, Pan D, Fu J, Sahu A, Hu X, Li Z, Traugh N, Bu X, Li B, Liu J, Freeman GJ, Brown MA, Wucherpfennig KW, Liu XS. Signatures of T cell dysfunction and exclusion predict cancer immunotherapy response. Nature Medicine. PMID 30127393 DOI: 10.1038/S41591-018-0136-1  0.302
2018 Lyu J, Yang EJ, Head SA, Ai N, Zhang B, Wu C, Li RJ, Liu Y, Chakravarty H, Zhang S, Tam KY, Dang Y, Kwon HJ, Ge W, Liu JO, et al. Astemizole Inhibits mTOR Signaling and Angiogenesis by Blocking Cholesterol Trafficking. International Journal of Biological Sciences. 14: 1175-1185. PMID 30123067 DOI: 10.7150/Ijbs.26011  0.805
2018 Pan T, Peng Z, Tan L, Zou F, Zhou N, Liu B, Liang L, Chen C, Liu J, Wu L, Liu G, Peng Z, Liu W, Ma X, Zhang J, et al. Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Potently Inhibit the Replication of Zika Viruses by Inducing the Degradation of AXL. Journal of Virology. PMID 30068645 DOI: 10.1128/JVI.01018-18  0.328
2018 Liu X, Sun Z, Li D, Deng J, Liu J, Ma K, Qin S, Si Y, Zhang T, Feng T, Liu Y, Tan Y. Polyphyllin I inhibits invasion and epithelial-mesenchymal transition via CIP2A/PP2A/ERK signaling in prostate cancer. International Journal of Oncology. PMID 29956727 DOI: 10.3892/ijo.2018.4464  0.31
2018 Bauer L, Ferla S, Head SA, Bhat S, Pasunooti KK, Shi WQ, Albulescu L, Liu JO, Brancale A, van Kuppeveld FJM, Strating JRPM. Structure-activity relationship study of itraconazole, a broad-range inhibitor of picornavirus replication that targets oxysterol-binding protein (OSBP). Antiviral Research. PMID 29807040 DOI: 10.1016/J.Antiviral.2018.05.010  0.839
2018 Yan S, Huang W, Gao J, Fu H, Liu J. Comparative metabolomic analysis of seed metabolites associated with seed storability in rice (Oryza sativa L.) during natural aging. Plant Physiology and Biochemistry : Ppb. 127: 590-598. PMID 29729608 DOI: 10.1016/j.plaphy.2018.04.020  0.406
2018 Lam C, Ferguson ID, Mariano MC, Lin YT, Murnane M, Liu H, Smith GA, Wong SW, Taunton J, Liu JO, Mitsiades CS, Hann BC, Aftab BT, Wiita AP. Repurposing tofacitinib as an anti-myeloma therapeutic to reverse growth-promoting effects of the bone marrow microenvironment. Haematologica. PMID 29622655 DOI: 10.3324/Haematol.2017.174482  0.6
2018 Cui CY, Liu J, Zheng HB, Jin XY, Zhao XY, Chang WQ, Sun B, Lou HX. Diversity-oriented synthesis of pyrazoles derivatives from flavones and isoflavones leads to the discovery of promising reversal agents of fluconazole resistance in Candida albicans. Bioorganic & Medicinal Chemistry Letters. PMID 29606575 DOI: 10.1016/j.bmcl.2018.03.066  0.319
2018 Zheng CJ, Yang LL, Liu J, Zhong L. JTC-801 exerts anti-proliferative effects in human osteosarcoma cells by inducing apoptosis. Journal of Receptor and Signal Transduction Research. 1-8. PMID 29447541 DOI: 10.1080/10799893.2018.1436561  0.311
2018 Jiang W, Zhou X, Li Z, Liu K, Wang W, Tan R, Cong X, Shan J, Zhan Y, Cui Z, Jiang L, Li Q, Shen S, Bai M, Cheng Y, ... ... Liu JO, et al. Prolyl 4-Hydroxylase 2 Promotes B-cell Lymphoma Progression via Hydroxylation of Carabin. Blood. PMID 29437589 DOI: 10.1182/Blood-2017-07-794875  0.632
2018 Young DJ, Liu JO, Small D. Combinatorial Approaches to Overcome Plasma Protein Inhibition of FLT3 Tyrosine Kinase Inhibitors Blood. 132: 1362-1362. DOI: 10.1182/Blood-2018-99-118820  0.41
2017 Zhang X, Saarinen AM, Hitosugi T, Wang Z, Wang L, Ho TH, Liu J. Inhibition of intracellular lipolysis promotes human cancer cell adaptation to hypoxia. Elife. 6. PMID 29256392 DOI: 10.7554/eLife.31132  0.31
2017 Li Z, Cheng Z, Raghothama C, Cui Z, Liu K, Li X, Jiang C, Jiang W, Tan M, Ni X, Pandey A, Liu JO, Dang Y. USP9X controls translation efficiency via deubiquitination of eukaryotic translation initiation factor 4A1. Nucleic Acids Research. PMID 29228324 DOI: 10.1093/Nar/Gkx1226  0.651
2017 Zhao L, Liu J, He C, Yan R, Zhou K, Cui Q, Meng X, Li X, Zhang Y, Nie Y, Zhang Y, Hu R, Liu Y, Zhao L, Chen M, et al. Protein kinase A determines platelet life span and survival by regulating apoptosis. The Journal of Clinical Investigation. PMID 29083324 DOI: 10.1172/Jci95109  0.339
2017 Lyu J, Yang EJ, Head SA, Ai N, Zhang B, Wu C, Li RJ, Liu Y, Yang C, Dang Y, Kwon HJ, Ge W, Liu JO, Shim JS. Pharmacological blockade of cholesterol trafficking by cepharanthine in endothelial cells suppresses angiogenesis and tumor growth. Cancer Letters. PMID 28923401 DOI: 10.1016/J.Canlet.2017.09.009  0.821
2017 Pan W, Zhu S, Qu K, Meeth K, Cheng J, He K, Ma H, Liao Y, Wen X, Roden C, Tobiasova Z, Wei Z, Zhao J, Liu J, Zheng J, et al. The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression. Immunity. 47: 284-297.e5. PMID 28813659 DOI: 10.1016/J.Immuni.2017.07.020  0.341
2017 Li Y, Liu J, Yang X, Dong Y, Liu Y, Chen M. Ginkgol C17:1 inhibits tumor growth by blunting the EGF- PI3K/Akt signaling pathway. Journal of Biomedical Research. 31: 232-239. PMID 28808215 DOI: 10.7555/JBR.31.20160039  0.306
2017 Liu J, Sun B, Zhao X, Xing J, Gao Y, Chang W, Ji J, Zheng H, Cui C, Ji A, Lou HX. Discovery of Potent Orally Active Protease-Activated Receptor 1 (PAR1) Antagonists Based on Andrographolide. Journal of Medicinal Chemistry. PMID 28745507 DOI: 10.1021/acs.jmedchem.7b00951  0.325
2017 Liu Q, Chen K, Liu Z, Huang Y, Zhao R, Wei L, Yu X, He J, Liu J, Qi J, Qin Y, Li B. BORIS up-regulates OCT4 via histone methylation to promote cancer stem cell-like properties in human liver cancer cells. Cancer Letters. PMID 28645561 DOI: 10.1016/j.canlet.2017.06.017  0.325
2017 Sun B, Liu J, Gao Y, Zheng HB, Li L, Hu QW, Yuan HQ, Lou HX. Design, synthesis and biological evaluation of nitrogen-containing macrocyclic bisbibenzyl derivatives as potent anticancer agents by targeting the lysosome. European Journal of Medicinal Chemistry. 136: 603-618. PMID 28570977 DOI: 10.1016/j.ejmech.2017.05.050  0.317
2017 Kosowicz JG, Lee J, Peiffer B, Guo Z, Chen J, Liao G, Hayward SD, Liu JO, Ambinder RF. Drug modulators of B cell signaling pathways and Epstein-Barr virus lytic activation. Journal of Virology. PMID 28566383 DOI: 10.1128/Jvi.00747-17  0.822
2017 Li Q, Zhu Y, Liu J, Yu X, Chen M, Dong N, Gong Y, Yuan Y. HpSlyD inducing CDX2 and VIL1 expression mediated through TCTP protein may contribute to intestinal metaplasia in the stomach. Scientific Reports. 7: 2278. PMID 28536478 DOI: 10.1038/s41598-017-02642-y  0.319
2017 McClary B, Zinshteyn B, Meyer M, Jouanneau M, Pellegrino S, Yusupova G, Schuller A, Reyes JCP, Lu J, Guo Z, Ayinde S, Luo C, Dang Y, Romo D, Yusupov M, ... ... Liu JO, et al. Inhibition of Eukaryotic Translation by the Antitumor Natural Product Agelastatin A. Cell Chemical Biology. PMID 28457705 DOI: 10.1016/J.Chembiol.2017.04.006  0.805
2017 Shi Z, Zhou H, Lu L, Li X, Fu Z, Liu J, Kang Y, Wei Z, Pan B, Liu L, Kong X, Feng S. The roles of microRNAs in spinal cord injury. The International Journal of Neuroscience. 1-43. PMID 28436759 DOI: 10.1080/00207454.2017.1323208  0.535
2017 Lu L, Zhou H, Pan B, Li X, Fu Z, Liu J, Shi Z, Chu T, Wei Z, Ning G, Feng S. c-Jun Amino-Terminal Kinase is Involved in Valproic Acid-Mediated Neuronal Differentiation of Mouse Embryonic NSCs and Neurite Outgrowth of NSC-Derived Neurons. Neurochemical Research. PMID 28321599 DOI: 10.1007/s11064-016-2167-7  0.556
2017 Vuckovic S, Vandyke K, Rickards DA, McCauley Winter P, Brown SH, Mitchell TW, Liu J, Lu J, Askenase PW, Yuriev E, Capuano B, Ramsland PA, Hill GR, Zannettino AC, Hutchinson AT. The cationic small molecule GW4869 is cytotoxic to high phosphatidylserine-expressing myeloma cells. British Journal of Haematology. PMID 28211573 DOI: 10.1111/Bjh.14561  0.374
2017 Head SA, Shi WQ, Yang EJ, Nacev BA, Hong SY, Pasunooti KK, Li RJ, Shim JS, Liu JO. Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis. Acs Chemical Biology. 12: 174-182. PMID 28103683 DOI: 10.1021/Acschembio.6B00849  0.831
2016 Liu AL, Liao HQ, Li ZhL, Liu J, Zhou CL, Guo ZF, Xie HY, Peng CY. New Insights into mTOR Signal Pathways in Ovarian-Related Diseases: Polycystic Ovary Syndrome and Ovarian Cancer Asian Pacific Journal of Cancer Prevention : Apjcp. 17: 5087-5094. PMID 28122439 DOI: 10.22034/APJCP.2016.17.12.5087  0.312
2016 John SF, Aniemeke E, Ha NP, Chong CR, Gu P, Zhou J, Zhang Y, Graviss EA, Liu JO, Olaleye OA. Characterization of 2-hydroxy-1-naphthaldehyde isonicotinoyl hydrazone as a novel inhibitor of methionine aminopeptidases from Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). PMID 27856197 DOI: 10.1016/J.Tube.2016.09.025  0.798
2016 Li RJ, Xu J, Fu C, Zhang J, Zheng YG, Jia H, Liu JO. Regulation of mTORC1 by lysosomal calcium and calmodulin. Elife. 5. PMID 27787197 DOI: 10.7554/Elife.19360  0.718
2016 Cho YS, Yen CN, Shim JS, Kang DH, Kang SW, Liu JO, Kwon HJ. Antidepressant indatraline induces autophagy and inhibits restenosis via suppression of mTOR/S6 kinase signaling pathway. Scientific Reports. 6: 34655. PMID 27694974 DOI: 10.1038/Srep34655  0.624
2016 Head SA, Liu JO. Identification of Small Molecule-binding Proteins in a Native Cellular Environment by Live-cell Photoaffinity Labeling. Journal of Visualized Experiments : Jove. PMID 27684515 DOI: 10.3791/54529  0.757
2016 Song Z, Chen CP, Liu J, Wen X, Sun H, Yuan H. Design, synthesis, and biological evaluation of (2E)-(2-oxo-1, 2-dihydro-3H-indol-3-ylidene)acetate derivatives as anti-proliferative agents through ROS-induced cell apoptosis. European Journal of Medicinal Chemistry. 124: 809-819. PMID 27643639 DOI: 10.1016/j.ejmech.2016.09.005  0.304
2016 Qiu H, Qian S, Head SA, Liu JO, Jin Z. Insights into the structure-activity relationship of the anticancer compound ZJ-101, a derivative of marine natural product superstolide A: A role played by the lactone moiety. Bioorganic & Medicinal Chemistry Letters. PMID 27595422 DOI: 10.1016/J.Bmcl.2016.08.046  0.77
2016 He QL, Minn I, Wang Q, Xu P, Head SA, Datan E, Yu B, Pomper MG, Liu JO. Targeted Delivery and Sustained Antitumor Activity of Triptolide through Glucose Conjugation. Angewandte Chemie (International Ed. in English). PMID 27574181 DOI: 10.1002/Anie.201606121  0.812
2016 Cheng D, Liu J, Han D, Zhang G, Gao W, Hsieh MH, Ng N, Kasibhatla S, Tompkins C, Li J, Steffy A, Sun F, Li C, Seidel HM, Harris JL, et al. Discovery of Pyridinyl Acetamide Derivatives as Potent, Selective, and Orally Bioavailable Porcupine Inhibitors. Acs Medicinal Chemistry Letters. 7: 676-80. PMID 27437076 DOI: 10.1021/Acsmedchemlett.6B00038  0.37
2016 Xiao S, Yang Z, Qiu X, Lv R, Liu J, Wu M, Liao Y, Liu Q. miR-29c contribute to glioma cells temozolomide sensitivity by targeting O6-methylguanine-DNA methyltransferases indirectely. Oncotarget. PMID 27384876 DOI: 10.18632/oncotarget.10357  0.325
2016 Qian S, Shah AK, Head SA, Liu JO, Jin Z. Insights into the structure-activity relationship of the anticancer compound ZJ-101, a derivative of marine natural product superstolide A: A critical role played by the conjugated trienyl lactone moiety. Bioorganic & Medicinal Chemistry Letters. PMID 27374243 DOI: 10.1016/J.Bmcl.2016.06.057  0.758
2016 Shah AK, Qian S, Zhang D, Head SA, Liu JO, Jin Z. Insights into the structure-activity relationship of the anticancer compound ZJ-101: A critical role played by the cyclohexene ring. Bioorganic & Medicinal Chemistry Letters. PMID 27133592 DOI: 10.1016/J.Bmcl.2016.04.044  0.766
2016 Romo D, Liu JO. Editorial: Strategies for cellular target identification of natural products. Natural Product Reports. PMID 27118358 DOI: 10.1039/c6np90016j  0.488
2016 Wang J, Wen X, Liu J, Sun H. Mitochondrial biogenesis Inhibitors for Anticancer Therapy: A Review of Recent Patents. Recent Patents On Anti-Cancer Drug Discovery. PMID 27086599 DOI: 10.2174/1574892811666160418123628  0.354
2016 Song J, Wang X, Zhu J, Liu J. Rapamycin causes growth arrest and inhibition of invasion in human chondrosarcoma cells. Journal of B.U.On. : Official Journal of the Balkan Union of Oncology. 21: 244-51. PMID 27061554  0.339
2016 Zhang Y, Zheng Y, Faheem A, Sun T, Li C, Li Z, Zhao D, Wu C, Liu J. A novel AKT inhibitor, AZD5363, inhibits phosphorylation of AKT downstream molecules, and activates phosphorylation of mTOR and SMG-1 dependent on the liver cancer cell type. Oncology Letters. 11: 1685-1692. PMID 26998062 DOI: 10.3892/ol.2016.4111  0.314
2016 Jouanneau M, McClary B, Reyes JC, Chen R, Chen Y, Plunkett W, Cheng X, Milinichik AZ, Albone EF, Liu JO, Romo D. Derivatization of agelastatin A leading to bioactive analogs and a trifunctional probe. Bioorganic & Medicinal Chemistry Letters. PMID 26951751 DOI: 10.1016/J.Bmcl.2016.02.051  0.802
2016 Gao J, Fu H, Zhou X, Chen Z, Luo Y, Cui B, Chen G, Liu J. Comparative proteomic analysis of seed embryo proteins associated with seed storability in rice (Oryza sativa L) during natural aging. Plant Physiology and Biochemistry : Ppb / Societe Francaise De Physiologie Vegetale. 103: 31-44. PMID 26950923 DOI: 10.1016/j.plaphy.2016.02.026  0.427
2016 Zhou Y, Liu J, Zheng M, Zheng S, Jiang C, Zhou X, Zhang D, Zhao J, Ye D, Zheng M, Jiang H, Liu D, Cheng J, Liu H. Structural optimization and biological evaluation of 1,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase. Acta Pharmaceutica Sinica. B. 6: 32-45. PMID 26904397 DOI: 10.1016/j.apsb.2015.11.004  0.32
2016 Shim JS, Li RJ, Bumpus N, Head S, Pasunooti K, Yang EJ, Lv J, Shi W, Liu JO. Divergence of Anti-angiogenic Activity and Hepatotoxicity of Different Stereoisomers of Itraconazole. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 26801248 DOI: 10.1158/1078-0432.Ccr-15-1888  0.807
2016 Liu J, Zhang L, Ren Y, Gao Y, Kang L, Lu S. Matrine inhibits the expression of adhesion molecules in activated vascular smooth muscle cells. Molecular Medicine Reports. PMID 26783147 DOI: 10.3892/mmr.2016.4767  0.306
2016 Fox JM, Moynihan JR, Mott BT, Mazzone JR, Anders NM, Brown PA, Rudek MA, Liu JO, Arav-Boger R, Posner GH, Civin CI, Chen X. Artemisinin-derived dimer ART-838 potently inhibited human acute leukemias, persisted in vivo, and synergized with antileukemic drugs. Oncotarget. PMID 26771236 DOI: 10.18632/Oncotarget.6896  0.604
2016 Li R, Xu J, Fu C, Zhang J, Zheng YG, Jia H, Liu JO. Author response: Regulation of mTORC1 by lysosomal calcium and calmodulin Elife. DOI: 10.7554/Elife.19360.017  0.657
2015 Head SA, Shi W, Zhao L, Gorshkov K, Pasunooti K, Chen Y, Deng Z, Li RJ, Shim JS, Tan W, Hartung T, Zhang J, Zhao Y, Colombini M, Liu JO. Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 26655341 DOI: 10.1073/Pnas.1512867112  0.832
2015 Liu J, Guo X, Hu R, Liu X, Wang S, Li S, Li Y, Yang G. Molecular Engineering of Aqueous Soluble Triarylboron-Compound-Based Two-Photon Fluorescent Probe for Mitochondria H2S with Analyte-Induced Finite Aggregation and Excellent Membrane Permeability. Analytical Chemistry. PMID 26634883 DOI: 10.1021/acs.analchem.5b04248  0.322
2015 Tang J, Guo H, Zhao M, Yang J, Tsoukalas D, Zhang B, Liu J, Xue C, Zhang W. Highly Stretchable Electrodes on Wrinkled Polydimethylsiloxane Substrates. Scientific Reports. 5: 16527. PMID 26585636 DOI: 10.1038/srep16527  0.334
2015 Lu J, Jiang C, Li X, Jiang L, Li Z, Schneider-Poetsch T, Liu J, Yu K, Liu JO, Jiang H, Luo C, Dang Y. A gating mechanism for Pi release governs the mRNA unwinding by eIF4AI during translation initiation. Nucleic Acids Research. PMID 26464436 DOI: 10.1093/Nar/Gkv1033  0.786
2015 Lee HG, Kim H, Kim EJ, Park PG, Dong SM, Choi TH, Kim H, Chong CR, Liu JO, Chen J, Ambinder RF, Hayward SD, Park JH, Lee JM. Targeted therapy for Epstein-Barr virus-associated gastric carcinoma using low-dose gemcitabine-induced lytic activation. Oncotarget. PMID 26427042 DOI: 10.18632/Oncotarget.5041  0.743
2015 Su XY, Lau JT, Mak WW, Choi KC, Feng TJ, Chen X, Liu CL, Liu J, Liu D, Chen L, Song JM, Zhang Y, Zhao GL, Zhu ZP, Cheng JQ. A preliminary validation of the Brief COPE instrument for assessing coping strategies among people living with HIV in China. Infectious Diseases of Poverty. 4: 41. PMID 26370135 DOI: 10.1186/S40249-015-0074-9  0.479
2015 Wang G, Rajpurohit SK, Delaspre F, Walker SL, White DT, Ceasrine A, Kuruvilla R, Li RJ, Shim JS, Liu JO, Parsons MJ, Mumm JS. First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass. Elife. 4. PMID 26218223 DOI: 10.7554/Elife.08261  0.772
2015 He R, Yu ZH, Zhang RY, Wu L, Gunawan AM, Lane BS, Shim JS, Zeng LF, He Y, Chen L, Wells CD, Liu JO, Zhang ZY. Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors. Acs Medicinal Chemistry Letters. 6: 782-6. PMID 26191366 DOI: 10.1021/Acsmedchemlett.5B00118  0.661
2015 Liu J, Zhang K, Mai X, Wei J, Liao Y, Zhong Y, Liu Y, Feng L, Liu C. Synthesis, Anticancer Evaluation and Docking Study of 3-Benzyloxyhydantoin Derivatives. Medicinal Chemistry (Shariqah (United Arab Emirates)). PMID 26152144 DOI: 10.2174/1573406411666150708111631  0.394
2015 Liu H, Lei C, Long K, Yang X, Zhu Z, Zhang L, Liu J. Mutant GNAQ promotes cell viability and migration of uveal melanoma cells through the activation of Notch signaling. Oncology Reports. 34: 295-301. PMID 25955651 DOI: 10.3892/or.2015.3949  0.306
2015 Shim JS, Li RJ, Lv J, Head SA, Yang EJ, Liu JO. Inhibition of angiogenesis by selective estrogen receptor modulators through blockade of cholesterol trafficking rather than estrogen receptor antagonism. Cancer Letters. 362: 106-15. PMID 25799952 DOI: 10.1016/J.Canlet.2015.03.022  0.809
2015 Ding H, Wang T, Xu D, Cha B, Liu J, Li Y. Dexamethasone-induced apoptosis of osteocytic and osteoblastic cells is mediated by TAK1 activation. Biochemical and Biophysical Research Communications. 460: 157-63. PMID 25753204 DOI: 10.1016/j.bbrc.2015.02.161  0.302
2015 Zhu Y, Chen M, Gong Y, Liu Z, Li A, Kang D, Han F, Liu J, Liu J, Yuan Y. Helicobacter pylori FKBP-type PPIase promotes gastric epithelial cell proliferation and anchorage-independent growth through activation of ERK-mediated mitogenic signaling pathway. Fems Microbiology Letters. 362. PMID 25687921 DOI: 10.1093/femsle/fnv023  0.334
2015 Strating JR, van der Linden L, Albulescu L, Bigay J, Arita M, Delang L, Leyssen P, van der Schaar HM, Lanke KH, Thibaut HJ, Ulferts R, Drin G, Schlinck N, Wubbolts RW, Sever N, ... ... Liu JO, et al. Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein. Cell Reports. 10: 600-15. PMID 25640182 DOI: 10.1016/J.Celrep.2014.12.054  0.811
2015 Saiyin H, Ardito-Abraham CM, Wu Y, Wei Y, Fang Y, Han X, Li J, Zhou P, Yi Q, Maitra A, Liu JO, Tuveson DA, Lou W, Yu L. Identification of novel vascular projections with cellular trafficking abilities on the microvasculature of pancreatic ductal adenocarcinoma. The Journal of Pathology. 236: 142-54. PMID 25561062 DOI: 10.1002/Path.4506  0.331
2015 He QL, Titov DV, Li J, Tan M, Ye Z, Zhao Y, Romo D, Liu JO. Covalent modification of a cysteine residue in the XPB subunit of the general transcription factor TFIIH through single epoxide cleavage of the transcription inhibitor triptolide. Angewandte Chemie (International Ed. in English). 54: 1859-63. PMID 25504624 DOI: 10.1002/Anie.201408817  0.809
2015 Wang G, Rajpurohit SK, Delaspre F, Walker SL, White DT, Ceasrine A, Kuruvilla R, Li R, Shim JS, Liu JO, Parsons MJ, Mumm JS. Author response: First quantitative high-throughput screen in zebrafish identifies novel pathways for increasing pancreatic β-cell mass Elife. DOI: 10.7554/Elife.08261.023  0.739
2015 Murnane M, Dhimolea E, Li R, Bariteau MA, Wheeler DD, Akhurst RJ, Logan AC, Munster P, Wiita A, Martin TG, Wolf JL, Liu JO, Mitsiades CS, Aftab BT. Defining Primary Marrow Microenvironment-Induced Synthetic Lethality and Resistance for 2,684 Approved Drugs Across Molecularly Distinct Forms of Multiple Myeloma Blood. 126: 503-503. DOI: 10.1182/Blood.V126.23.503.503  0.379
2014 Zhang W, Lv S, Liu J, Zang Z, Yin J, An N, Yang H, Song Y. PCI-24781 down-regulates EZH2 expression and then promotes glioma apoptosis by suppressing the PIK3K/Akt/mTOR pathway. Genetics and Molecular Biology. 37: 716-24. PMID 25505847 DOI: 10.1590/S1415-47572014005000011  0.312
2014 Rasul A, Zhao BJ, Liu J, Liu B, Sun JX, Li J, Li XM. Molecular mechanisms of casticin action: an update on its antitumor functions. Asian Pacific Journal of Cancer Prevention : Apjcp. 15: 9049-58. PMID 25422178  0.323
2014 Cai Y, Tan X, Liu J, Shen Y, Wu D, Ren M, Huang P, Yu D. Inhibition of PI3K/Akt/mTOR signaling pathway enhances the sensitivity of the SKOV3/DDP ovarian cancer cell line to cisplatin in vitro. Chinese Journal of Cancer Research = Chung-Kuo Yen Cheng Yen Chiu. 26: 564-72. PMID 25400422 DOI: 10.3978/j.issn.1000-9604.2014.08.20  0.313
2014 Jiang W, Huang H, Ding L, Zhu P, Saiyin H, Ji G, Zuo J, Han D, Pan Y, Ding D, Ma X, Zhang Y, Wu J, Yi Q, Liu JO, et al. Regulation of cell cycle of hepatocellular carcinoma by NF90 through modulation of cyclin E1 mRNA stability. Oncogene. PMID 25399696 DOI: 10.1038/Onc.2014.373  0.576
2014 Tong SJ, Liu J, Wang X, Qu LX. microRNA-181 promotes prostate cancer cell proliferation by regulating DAX-1 expression. Experimental and Therapeutic Medicine. 8: 1296-1300. PMID 25187843 DOI: 10.3892/etm.2014.1846  0.307
2014 Liu J, Tong SJ, Wang X, Qu LX. Farnesoid X receptor inhibits LNcaP cell proliferation via the upregulation of PTEN. Experimental and Therapeutic Medicine. 8: 1209-1212. PMID 25187826 DOI: 10.3892/etm.2014.1894  0.354
2014 Wu J, Feng X, Zhang B, Li J, Xu X, Liu J, Wang X, Wang J, Tong X. Blocking the bFGF/STAT3 interaction through specific signaling pathways induces apoptosis in glioblastoma cells. Journal of Neuro-Oncology. 120: 33-41. PMID 25048528 DOI: 10.1007/s11060-014-1529-8  0.311
2014 Shim JS, Liu JO. Recent advances in drug repositioning for the discovery of new anticancer drugs. International Journal of Biological Sciences. 10: 654-63. PMID 25013375 DOI: 10.7150/Ijbs.9224  0.591
2014 Wang M, Shim JS, Li RJ, Dang Y, He Q, Das M, Liu JO. Identification of an old antibiotic clofoctol as a novel activator of unfolded protein response pathways and an inhibitor of prostate cancer. British Journal of Pharmacology. 171: 4478-89. PMID 24903412 DOI: 10.1111/Bph.12800  0.801
2014 Wissing MD, Dadon T, Kim E, Piontek KB, Shim JS, Kaelber NS, Liu JO, Kachhap SK, Nelkin BD. Small-molecule screening of PC3 prostate cancer cells identifies tilorone dihydrochloride to selectively inhibit cell growth based on cyclin-dependent kinase 5 expression. Oncology Reports. 32: 419-24. PMID 24841903 DOI: 10.3892/Or.2014.3174  0.621
2014 Sun L, Zhang Y, Zhao B, Deng M, Liu J, Li X, Hou J, Gui M, Zhang S, Li X, Gao GF, Meng S. A new unconventional HLA-A2-restricted epitope from HBV core protein elicits antiviral cytotoxic T lymphocytes. Protein & Cell. 5: 317-27. PMID 24659387 DOI: 10.1007/s13238-014-0041-4  0.335
2014 Jing X, Shi Q, Bi W, Zeng Z, Liang Y, Wu X, Xiao S, Liu J, Yang L, Tao E. Rifampicin protects PC12 cells from rotenone-induced cytotoxicity by activating GRP78 via PERK-eIF2α-ATF4 pathway. Plos One. 9: e92110. PMID 24638036 DOI: 10.1371/journal.pone.0092110  0.315
2014 Dong J, Gong Y, Liu J, Chen X, Wen X, Sun H. Synthesis and biological evaluation of all eight stereoisomers of DPP-IV inhibitor saxagliptin. Bioorganic & Medicinal Chemistry. 22: 1383-93. PMID 24457090 DOI: 10.1016/j.bmc.2013.12.061  0.333
2014 Low WK, Li J, Zhu M, Kommaraju SS, Shah-Mittal J, Hull K, Liu JO, Romo D. Second-generation derivatives of the eukaryotic translation initiation inhibitor pateamine A targeting eIF4A as potential anticancer agents. Bioorganic & Medicinal Chemistry. 22: 116-25. PMID 24359706 DOI: 10.1016/J.Bmc.2013.11.046  0.628
2014 Wu J, Liu J, Jia R, Song H. Nur77 inhibits androgen-induced bladder cancer growth. Cancer Investigation. 31: 654-60. PMID 24299210 DOI: 10.3109/07357907.2013.853077  0.319
2014 Heckmann BL, Yang X, Zhang X, Liu J. The autophagic inhibitor 3-methyladenine potently stimulates PKA-dependent lipolysis in adipocytes. British Journal of Pharmacology. 168: 163-71. PMID 22817685 DOI: 10.1111/j.1476-5381.2012.02110.x  0.328
2014 Chalugun P, Shim JS, Korangath PC, Sukumar S, Liu JO. Abstract 443: Synergistic inhibition of HER2 positive breast cancer by triptolide and lapatinib Cancer Research. 74: 443-443. DOI: 10.1158/1538-7445.Am2014-443  0.578
2014 Chalugun P, Shim J, Korangath P, Sukumar S, Liu J. 98 Synergistic inhibition of HER2 positive breast cancer by triptolide and lapatinib European Journal of Cancer. 50: 36. DOI: 10.1016/S0959-8049(14)70224-2  0.488
2013 Liu J, Pan S, Hsieh MH, Ng N, Sun F, Wang T, Kasibhatla S, Schuller AG, Li AG, Cheng D, Li J, Tompkins C, Pferdekamper A, Steffy A, Cheng J, et al. Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974. Proceedings of the National Academy of Sciences of the United States of America. 110: 20224-9. PMID 24277854 DOI: 10.1073/Pnas.1314239110  0.494
2013 Lin Y, Liu J, Liu X, Ou Y, Li M, Zhang H, Song B, Xie C. Interaction proteins of invertase and invertase inhibitor in cold-stored potato tubers suggested a protein complex underlying post-translational regulation of invertase. Plant Physiology and Biochemistry : Ppb / Sociã©Tã© Franã§Aise De Physiologie Vã©Gã©Tale. 73: 237-44. PMID 24161651 DOI: 10.1016/j.plaphy.2013.09.012  0.301
2013 Ding G, Feng C, Jiang H, Ding Q, Zhang L, Na R, Xu H, Liu J. Combination of rapamycin, CI-1040, and 17-AAG inhibits metastatic capacity of prostate cancer via Slug inhibition. Plos One. 8: e77400. PMID 24130883 DOI: 10.1371/journal.pone.0077400  0.347
2013 Yang M, Li SN, Anjum KM, Gui LX, Zhu SS, Liu J, Chen JK, Liu QF, Ye GD, Wang WJ, Wu JF, Cai WY, Sun GB, Liu YJ, Liu RF, et al. A double-negative feedback loop between Wnt-β-catenin signaling and HNF4α regulates epithelial-mesenchymal transition in hepatocellular carcinoma. Journal of Cell Science. 126: 5692-703. PMID 24101726 DOI: 10.1242/jcs.135053  0.461
2013 Liu J, Zhang R, Chen F, Yu C, Sun Y, Jia C, Zhang L, Salahuddin T, Li X, Lang J, Song X. MGMT Leu84Phe polymorphism contributes to cancer susceptibility: evidence from 44 case-control studies. Plos One. 8: e75367. PMID 24086516 DOI: 10.1371/journal.pone.0075367  0.305
2013 Kishor C, Arya T, Reddi R, Chen X, Saddanapu V, Marapaka AK, Gumpena R, Ma D, Liu JO, Addlagatta A. Identification, biochemical and structural evaluation of species-specific inhibitors against type I methionine aminopeptidases. Journal of Medicinal Chemistry. 56: 5295-305. PMID 23767698 DOI: 10.1021/Jm400395P  0.585
2013 Liu C, Ma H, Wu J, Huang Q, Liu JO, Yu L. Arginine68 is an essential residue for the C-terminal cleavage of human Atg8 family proteins. Bmc Cell Biology. 14: 27. PMID 23721406 DOI: 10.1186/1471-2121-14-27  0.344
2013 Chang BH, Liu X, Liu J, Quan FS, Guo ZK, Zhang Y. Developmental expression and possible functional roles of mouse Nlrp4e in preimplantation embryos. In Vitro Cellular & Developmental Biology. Animal. 49: 548-53. PMID 23708922 DOI: 10.1007/s11626-013-9638-9  0.577
2013 Li G, Diogo D, Wu D, Spoonamore J, Dancik V, Franke L, Kurreeman F, Rossin EJ, Duclos G, Hartland C, Zhou X, Li K, Liu J, De Jager PL, Siminovitch KA, et al. Human genetics in rheumatoid arthritis guides a high-throughput drug screen of the CD40 signaling pathway. Plos Genetics. 9: e1003487. PMID 23696745 DOI: 10.1371/Journal.Pgen.1003487  0.544
2013 Zhang Y, Ren Y, Wu Y, Zhao B, Qiu L, Li X, Xu D, Liu J, Gao GF, Meng S. The L60V variation in hepatitis B virus core protein elicits new epitope-specific cytotoxic T lymphocytes and enhances viral replication. Journal of Virology. 87: 8075-84. PMID 23678186 DOI: 10.1128/JVI.00577-13  0.32
2013 Kong X, Peng B, Yang Y, Zhang P, Qin B, Han D, Wang C, Dang Y, Liu JO, Yu L. p53 Represses transcription of RING finger LIM domain-binding protein RLIM through Sp1. Plos One. 8: e62832. PMID 23650532 DOI: 10.1371/Journal.Pone.0062832  0.645
2013 Zhang F, Bhat S, Gabelli SB, Chen X, Miller MS, Nacev BA, Cheng YL, Meyers DJ, Tenney K, Shim JS, Crews P, Amzel LM, Ma D, Liu JO. Pyridinylquinazolines selectively inhibit human methionine aminopeptidase-1 in cells Journal of Medicinal Chemistry. 56: 3996-4016. PMID 23634668 DOI: 10.1021/Jm400227Z  0.818
2013 Fatokun AA, Liu JO, Dawson VL, Dawson TM. Identification through high-throughput screening of 4'-methoxyflavone and 3',4'-dimethoxyflavone as novel neuroprotective inhibitors of parthanatos. British Journal of Pharmacology. 169: 1263-78. PMID 23550801 DOI: 10.1111/Bph.12201  0.389
2013 Rudin CM, Brahmer JR, Juergens RA, Hann CL, Ettinger DS, Sebree R, Smith R, Aftab BT, Huang P, Liu JO. Phase 2 study of pemetrexed and itraconazole as second-line therapy for metastatic nonsquamous non-small-cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 8: 619-23. PMID 23546045 DOI: 10.1097/Jto.0B013E31828C3950  0.36
2013 Bhat S, Shim JS, Liu JO. Tricyclic thiazoles are a new class of angiogenesis inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 2733-7. PMID 23518276 DOI: 10.1016/J.Bmcl.2013.02.067  0.796
2013 Zhang P, Yang X, Zhang F, Gabelli SB, Wang R, Zhang Y, Bhat S, Chen X, Furlani M, Amzel LM, Liu JO, Ma D. Pyridinylpyrimidines selectively inhibit human methionine aminopeptidase-1. Bioorganic & Medicinal Chemistry. 21: 2600-17. PMID 23507151 DOI: 10.1016/J.Bmc.2013.02.023  0.826
2013 Liu X, Lin Y, Liu J, Song B, Ou Y, Zhang H, Li M, Xie C. StInvInh2 as an inhibitor of StvacINV1 regulates the cold-induced sweetening of potato tubers by specifically capping vacuolar invertase activity. Plant Biotechnology Journal. 11: 640-7. PMID 23421503 DOI: 10.1111/pbi.12054  0.311
2013 Wissing MD, Mendonca J, Kim E, Kim E, Shim JS, Kaelber NS, Kant H, Hammers H, Commes T, Van Diest PJ, Liu JO, Kachhap SK. Identification of cetrimonium bromide and irinotecan as compounds with synthetic lethality against NDRG1 deficient prostate cancer cells. Cancer Biology & Therapy. 14: 401-10. PMID 23377825 DOI: 10.4161/Cbt.23759  0.612
2013 Kamiyama H, Rauenzahn S, Shim JS, Karikari CA, Feldmann G, Hua L, Kamiyama M, Schuler FW, Lin MT, Beaty RM, Karanam B, Liang H, Mullendore ME, Mo G, Hidalgo M, ... ... Liu JO, et al. Personalized chemotherapy profiling using cancer cell lines from selectable mice. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 1139-46. PMID 23340293 DOI: 10.1158/1078-0432.Ccr-12-2127  0.578
2013 Choi SM, Kim Y, Shim JS, Park JT, Wang RH, Leach SD, Liu JO, Deng C, Ye Z, Jang YY. Efficient drug screening and gene correction for treating liver disease using patient-specific stem cells. Hepatology (Baltimore, Md.). 57: 2458-68. PMID 23325555 DOI: 10.1002/Hep.26237  0.615
2013 Zhang L, Dong J, Zhang Y, Liu J, Zhang L, Sun H. Design, synthesis, and biological evaluation of potent photoaffinity probes of oleanolic acid. Medicinal Chemistry. 9: 294-302. PMID 22931495 DOI: 10.2174/1573406411309020012  0.382
2013 Zhang L, Dong J, Liu J, Zhang L, Kong L, Yao H, Sun H. Synthesis and biological evaluation of novel pentacyclic triterpene derivatives as potential PPARγ agonists. Medicinal Chemistry (Shariqah (United Arab Emirates)). 9: 118-25. PMID 22779802 DOI: 10.2174/157340613804488413  0.405
2013 Xiao Q, Qu K, Wang C, Kong Y, Liu C, Jiang D, Saiyin H, Jia F, Ni C, Chen T, Zhang Y, Zhang P, Qin W, Sun Q, Wang H, ... ... Liu J, et al. HDGF-related protein-3 is required for anchorage-independent survival and chemoresistance in hepatocellular carcinomas Gut. 62: 440-451. PMID 22490522 DOI: 10.1136/Gutjnl-2011-300781  0.356
2013 Kamiyama H, Rauenzahn S, Shim JS, Liu JO, Maitra A, Eshleman JR. Abstract 4155: Personalized chemosensitivity profiling of cancers isolated from genetically-engineered mice. Cancer Research. 73: 4155-4155. DOI: 10.1158/1538-7445.Am2013-4155  0.58
2012 Jing C, Na R, Wang B, Liu H, Zhang L, Liu J, Wang M, Zhong J, Kwon O, Guo H. Phosphine-Catalyzed [3+2] and [4+3]Annulation Reactions of C,N-Cyclic Azomethine Imines with Allenoates. Advanced Synthesis & Catalysis. 354: 1023-1034. PMID 25525424 DOI: 10.1002/Adsc.201100831  0.452
2012 Zhang L, Chen X, Liu J, Zhu Q, Leng Y, Luo X, Jiang H, Liu H. Discovery of novel dual-action antidiabetic agents that inhibit glycogen phosphorylase and activate glucokinase. European Journal of Medicinal Chemistry. 58: 624-39. PMID 23178962 DOI: 10.1016/j.ejmech.2012.06.020  0.307
2012 Zhou QG, Jiang JP, Wu SJ, Tian JW, Chen JH, Yu XQ, Chen PY, Mei CL, Xiong F, Shi W, Zhou W, Liu XS, Sun SR, Xie D, Liu J, et al. Current pattern of Chinese dialysis units: a cohort study in a representative sample of units. Chinese Medical Journal. 125: 3434-9. PMID 23044302  0.46
2012 Shim JS, Rao R, Beebe K, Neckers L, Han I, Nahta R, Liu JO. Selective inhibition of HER2-positive breast cancer cells by the HIV protease inhibitor nelfinavir. Journal of the National Cancer Institute. 104: 1576-90. PMID 23042933 DOI: 10.1093/Jnci/Djs396  0.609
2012 Hou F, Jiang J, Chen J, Yu X, Zhou Q, Chen P, Mei C, Xiong F, Shi W, Zhou W, Liu X, Sun S, Xie D, Liu J, Zhang P, et al. China collaborative study on dialysis: a multi-centers cohort study on cardiovascular diseases in patients on maintenance dialysis. Bmc Nephrology. 13: 94. PMID 22935444 DOI: 10.1186/1471-2369-13-94  0.463
2012 Miller E, Yang J, DeRan M, Wu C, Su AI, Bonamy GM, Liu J, Peters EC, Wu X. Identification of serum-derived sphingosine-1-phosphate as a small molecule regulator of YAP. Chemistry & Biology. 19: 955-62. PMID 22884261 DOI: 10.1016/J.Chembiol.2012.07.005  0.308
2012 Chen XY, Gu XT, Saiyin H, Wan B, Zhang YJ, Li J, Wang YL, Gao R, Wang YF, Dong WP, Najjar SM, Zhang CY, Ding HF, Liu JO, Yu L. Brain-selective kinase 2 (BRSK2) phosphorylation on PCTAIRE1 negatively regulates glucose-stimulated insulin secretion in pancreatic β-cells. The Journal of Biological Chemistry. 287: 30368-75. PMID 22798068 DOI: 10.1074/Jbc.M112.375618  0.352
2012 Krátký M, Vinšová J, Novotná E, Mandíková J, Wsól V, Trejtnar F, Ulmann V, Stolaříková J, Fernandes S, Bhat S, Liu JO. Salicylanilide derivatives block Mycobacterium tuberculosis through inhibition of isocitrate lyase and methionine aminopeptidase. Tuberculosis (Edinburgh, Scotland). 92: 434-9. PMID 22765970 DOI: 10.1016/J.Tube.2012.06.001  0.739
2012 Zhou Q, Wu S, Jiang J, Tian J, Chen J, Yu X, Chen P, Mei C, Xiong F, Shi W, Zhou W, Liu X, Sun S, Xie DI, Liu J, et al. Accumulation of circulating advanced oxidation protein products is an independent risk factor for ischaemic heart disease in maintenance haemodialysis patients. Nephrology (Carlton, Vic.). 17: 642-9. PMID 22738256 DOI: 10.1111/j.1440-1797.2012.01640.x  0.479
2012 Bhat S, Olaleye O, Meyer KJ, Shi W, Zhang Y, Liu JO. Analogs of N'-hydroxy-N-(4H,5H-naphtho[1,2-d]thiazol-2-yl)methanimidamide inhibit Mycobacterium tuberculosis methionine aminopeptidases. Bioorganic & Medicinal Chemistry. 20: 4507-13. PMID 22704656 DOI: 10.1016/J.Bmc.2012.05.022  0.805
2012 Liu-Chittenden Y, Huang B, Shim JS, Chen Q, Lee SJ, Anders RA, Liu JO, Pan D. Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP. Genes & Development. 26: 1300-5. PMID 22677547 DOI: 10.1101/Gad.192856.112  0.615
2012 Bhat S, Shim JS, Zhang F, Chong CR, Liu JO. Substituted oxines inhibit endothelial cell proliferation and angiogenesis. Organic & Biomolecular Chemistry. 10: 2979-92. PMID 22391578 DOI: 10.1039/C2Ob06978D  0.834
2012 Wang C, An J, Zhang P, Xu C, Gao K, Wu D, Wang D, Yu H, Liu JO, Yu L. The Nedd4-like ubiquitin E3 ligases target angiomotin/p130 to ubiquitin-dependent degradation. The Biochemical Journal. 444: 279-89. PMID 22385262 DOI: 10.1042/Bj20111983  0.372
2012 Shamay M, Liu J, Li R, Liao G, Shen L, Greenway M, Hu S, Zhu J, Xie Z, Ambinder RF, Qian J, Zhu H, Hayward SD. A protein array screen for Kaposi's sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere shortening. Journal of Virology. 86: 5179-91. PMID 22379092 DOI: 10.1128/Jvi.00169-12  0.336
2012 Titov DV, Liu JO. Identification and validation of protein targets of bioactive small molecules. Bioorganic & Medicinal Chemistry. 20: 1902-9. PMID 22226983 DOI: 10.1016/J.Bmc.2011.11.070  0.637
2012 Xing S, Bhat S, Shroff NS, Zhang H, Lopez JA, Margolick JB, Liu JO, Siliciano RF. Novel structurally related compounds reactivate latent HIV-1 in a bcl-2-transduced primary CD4+ T cell model without inducing global T cell activation. The Journal of Antimicrobial Chemotherapy. 67: 398-403. PMID 22160146 DOI: 10.1093/Jac/Dkr496  0.695
2012 Peng CC, Shi W, Lutz JD, Kunze KL, Liu JO, Nelson WL, Isoherranen N. Stereospecific metabolism of itraconazole by CYP3A4: dioxolane ring scission of azole antifungals. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 426-35. PMID 22106171 DOI: 10.1124/Dmd.111.042739  0.44
2012 Nacev BA, Grassi P, Dell A, Haslam SM, Liu JO. Abstract 2316: Itraconazole, an antifungal drug with anti-angiogenic activity, inhibits VEGFR2 trafficking, glycosylation, and signaling in endothelial cells Cancer Research. 72: 2316-2316. DOI: 10.1158/1538-7445.Am2012-2316  0.764
2011 Platz EA, Yegnasubramanian S, Liu JO, Chong CR, Shim JS, Kenfield SA, Stampfer MJ, Willett WC, Giovannucci E, Nelson WG. A novel two-stage, transdisciplinary study identifies digoxin as a possible drug for prostate cancer treatment. Cancer Discovery. 1: 68-77. PMID 22140654 DOI: 10.1158/2159-8274.Cd-10-0020  0.769
2011 Olaleye O, Raghunand TR, Bhat S, Chong C, Gu P, Zhou J, Zhang Y, Bishai WR, Liu JO. Characterization of clioquinol and analogues as novel inhibitors of methionine aminopeptidases from Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 91: S61-5. PMID 22115541 DOI: 10.1016/J.Tube.2011.10.012  0.807
2011 Rovira M, Huang W, Yusuff S, Shim JS, Ferrante AA, Liu JO, Parsons MJ. Chemical screen identifies FDA-approved drugs and target pathways that induce precocious pancreatic endocrine differentiation. Proceedings of the National Academy of Sciences of the United States of America. 108: 19264-9. PMID 22084084 DOI: 10.1073/Pnas.1113081108  0.602
2011 Nacev BA, Grassi P, Dell A, Haslam SM, Liu JO. The antifungal drug itraconazole inhibits vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, trafficking, and signaling in endothelial cells. The Journal of Biological Chemistry. 286: 44045-56. PMID 22025615 DOI: 10.1074/Jbc.M111.278754  0.768
2011 Nacev BA, Liu JO. Synergistic inhibition of endothelial cell proliferation, tube formation, and sprouting by cyclosporin A and itraconazole. Plos One. 6: e24793. PMID 21969860 DOI: 10.1371/Journal.Pone.0024793  0.776
2011 Leung E, Datti A, Cossette M, Goodreid J, McCaw SE, Mah M, Nakhamchik A, Ogata K, El Bakkouri M, Cheng YQ, Wodak SJ, Eger BT, Pai EF, Liu J, Gray-Owen S, et al. Activators of cylindrical proteases as antimicrobials: identification and development of small molecule activators of ClpP protease. Chemistry & Biology. 18: 1167-78. PMID 21944755 DOI: 10.1016/J.Chembiol.2011.07.023  0.333
2011 Shi W, Nacev BA, Aftab BT, Head S, Rudin CM, Liu JO. Itraconazole side chain analogues: structure-activity relationship studies for inhibition of endothelial cell proliferation, vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, and hedgehog signaling. Journal of Medicinal Chemistry. 54: 7363-74. PMID 21936514 DOI: 10.1021/Jm200944B  0.834
2011 Liu J, Xu X, Feng X, Zhang B, Wang J. Adenovirus-mediated delivery of bFGF small interfering RNA reduces STAT3 phosphorylation and induces the depolarization of mitochondria and apoptosis in glioma cells U251. Journal of Experimental & Clinical Cancer Research : Cr. 30: 80. PMID 21906308 DOI: 10.1186/1756-9966-30-80  0.305
2011 Aftab BT, Dobromilskaya I, Liu JO, Rudin CM. Itraconazole inhibits angiogenesis and tumor growth in non-small cell lung cancer. Cancer Research. 71: 6764-72. PMID 21896639 DOI: 10.1158/0008-5472.Can-11-0691  0.431
2011 Chamni S, He QL, Dang Y, Bhat S, Liu JO, Romo D. Diazo reagents with small steric footprints for simultaneous arming/SAR studies of alcohol-containing natural products via O-H insertion. Acs Chemical Biology. 6: 1175-81. PMID 21894934 DOI: 10.1021/Cb2002686  0.799
2011 Li W, Bhat S, Liu JO. A simple and efficient route to the FKBP-binding domain from rapamycin. Tetrahedron Letters. 52: 5070-5072. PMID 21894238 DOI: 10.1016/J.Tetlet.2011.07.094  0.713
2011 Liu J, Johnson K, Li J, Piamonte V, Steffy BM, Hsieh MH, Ng N, Zhang J, Walker JR, Ding S, Muneoka K, Wu X, Glynne R, Schultz PG. Regenerative phenotype in mice with a point mutation in transforming growth factor beta type I receptor (TGFBR1). Proceedings of the National Academy of Sciences of the United States of America. 108: 14560-5. PMID 21841138 DOI: 10.1073/Pnas.1111056108  0.387
2011 Dang Y, Schneider-Poetsch T, Eyler DE, Jewett JC, Bhat S, Rawal VH, Green R, Liu JO. Inhibition of eukaryotic translation elongation by the antitumor natural product Mycalamide B. Rna (New York, N.Y.). 17: 1578-88. PMID 21693620 DOI: 10.1261/Rna.2624511  0.817
2011 Nacev BA, Low WK, Huang Z, Su TT, Su Z, Alkuraya H, Kasuga D, Sun W, Träger M, Braun M, Fischer G, Zhang K, Liu JO. A calcineurin-independent mechanism of angiogenesis inhibition by a nonimmunosuppressive cyclosporin A analog. The Journal of Pharmacology and Experimental Therapeutics. 338: 466-75. PMID 21562139 DOI: 10.1124/Jpet.111.180851  0.847
2011 Huang C, Jiang T, Zhu L, Liu J, Cao J, Huang KJ, Qiu ZJ. STAT3-targeting RNA interference inhibits pancreatic cancer angiogenesis in vitro and in vivo. International Journal of Oncology. 38: 1637-44. PMID 21479358 DOI: 10.3892/ijo.2011.1000  0.331
2011 Wilson BA, Wang H, Nacev BA, Mease RC, Liu JO, Pomper MG, Isaacs WB. High-throughput screen identifies novel inhibitors of cancer biomarker α-methylacyl coenzyme A racemase (AMACR/P504S). Molecular Cancer Therapeutics. 10: 825-38. PMID 21441411 DOI: 10.1158/1535-7163.Mct-10-0902  0.749
2011 Titov DV, Gilman B, He QL, Bhat S, Low WK, Dang Y, Smeaton M, Demain AL, Miller PS, Kugel JF, Goodrich JA, Liu JO. XPB, a subunit of TFIIH, is a target of the natural product triptolide. Nature Chemical Biology. 7: 182-8. PMID 21278739 DOI: 10.1038/Nchembio.522  0.823
2011 Liu JO, Titov DV, Dang Y, He Q. Regulator of Ras depalmitoylation and retrograde trafficking: a new hat for FKBP. Molecular Cell. 41: 131-3. PMID 21255722 DOI: 10.1016/J.Molcel.2011.01.009  0.766
2011 Lin J, Haffner MC, Zhang Y, Lee BH, Brennen WN, Britton J, Kachhap SK, Shim JS, Liu JO, Nelson WG, Yegnasubramanian S, Carducci MA. Disulfiram is a DNA demethylating agent and inhibits prostate cancer cell growth. The Prostate. 71: 333-43. PMID 20809552 DOI: 10.1002/Pros.21247  0.615
2011 Aftab BT, Dobromilskaya I, Hann CL, Liu JO, Rudin CM. Abstract 3271: Inhibition of angiogenesis and tumor growth by itraconazole in primary xenograft models of human non-small cell lung cancer Cancer Research. 71: 3271-3271. DOI: 10.1158/1538-7445.Am2011-3271  0.346
2011 Wissing MD, Kim E, Dadon T, Shim JS, Mendonca J, Piontek K, Liu JO, Carducci MA, Kachhap SK, Nelkin BD. Abstract 2976: Small molecule screening of prostate and pancreatic cancer cell lines identifies tilorone dihydrochloride as a compound that selectively inhibits growth in cells with inhibited cyclin-dependent kinase 5 Cancer Research. 71: 2976-2976. DOI: 10.1158/1538-7445.Am2011-2976  0.622
2011 Aftab BT, Shi W, Nacev BA, Head S, Liu JO, Rudin CM. Abstract C147: Itraconazole side-chain analogs reveal a distinct structure-activity relationship for inhibition of hedgehog pathway signaling. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-C147  0.842
2010 Pan S, Wu X, Jiang J, Gao W, Wan Y, Cheng D, Han D, Liu J, Englund NP, Wang Y, Peukert S, Miller-Moslin K, Yuan J, Guo R, Matsumoto M, et al. Discovery of NVP-LDE225, a Potent and Selective Smoothened Antagonist. Acs Medicinal Chemistry Letters. 1: 130-4. PMID 24900187 DOI: 10.1021/Ml1000307  0.307
2010 Shi W, Nacev BA, Bhat S, Liu JO. Impact of Absolute Stereochemistry on the Antiangiogenic and Antifungal Activities of Itraconazole. Acs Medicinal Chemistry Letters. 1: 155-159. PMID 21892383 DOI: 10.1021/Ml1000068  0.807
2010 Shim JS, Matsui Y, Bhat S, Nacev BA, Xu J, Bhang HE, Dhara S, Han KC, Chong CR, Pomper MG, So A, Liu JO. Effect of nitroxoline on angiogenesis and growth of human bladder cancer. Journal of the National Cancer Institute. 102: 1855-73. PMID 21088277 DOI: 10.1093/Jnci/Djq457  0.816
2010 Zhu P, Jiang W, Cao L, Yu W, Pei Y, Yang X, Wan B, Liu JO, Yi Q, Yu L. IL-2 mRNA stabilization upon PMA stimulation is dependent on NF90-Ser647 phosphorylation by protein kinase CbetaI. Journal of Immunology (Baltimore, Md. : 1950). 185: 5140-9. PMID 20870937 DOI: 10.4049/Jimmunol.1000849  0.318
2010 Huang W, Ding L, Huang Q, Hu H, Liu S, Yang X, Hu X, Dang Y, Shen S, Li J, Ji X, Jiang S, Liu JO, Yu L. Carbonyl reductase 1 as a novel target of (-)-epigallocatechin gallate against hepatocellular carcinoma. Hepatology (Baltimore, Md.). 52: 703-14. PMID 20683966 DOI: 10.1002/Hep.23723  0.683
2010 Liu J, Afroza H, Rader DJ, Jin W. Angiopoietin-like protein 3 inhibits lipoprotein lipase activity through enhancing its cleavage by proprotein convertases. The Journal of Biological Chemistry. 285: 27561-70. PMID 20581395 DOI: 10.1074/Jbc.M110.144279  0.344
2010 Xiao Q, Zhang F, Nacev BA, Liu JO, Pei D. Protein N-terminal processing: substrate specificity of Escherichia coli and human methionine aminopeptidases. Biochemistry. 49: 5588-99. PMID 20521764 DOI: 10.1021/Bi1005464  0.774
2010 Li W, Dang Y, Liu JO, Yu B. Structural and stereochemical requirements of the spiroketal group of hippuristanol for antiproliferative activity. Bioorganic & Medicinal Chemistry Letters. 20: 3112-5. PMID 20409710 DOI: 10.1016/J.Bmcl.2010.03.093  0.671
2010 Kim J, Tang JY, Gong R, Kim J, Lee JJ, Clemons KV, Chong CR, Chang KS, Fereshteh M, Gardner D, Reya T, Liu JO, Epstein EH, Stevens DA, Beachy PA. Itraconazole, a commonly used antifungal that inhibits Hedgehog pathway activity and cancer growth. Cancer Cell. 17: 388-99. PMID 20385363 DOI: 10.1016/J.Ccr.2010.02.027  0.747
2010 Xu J, Dang Y, Ren YR, Liu JO. Cholesterol trafficking is required for mTOR activation in endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 107: 4764-9. PMID 20176935 DOI: 10.1073/Pnas.0910872107  0.825
2010 Olaleye O, Raghunand TR, Bhat S, He J, Tyagi S, Lamichhane G, Gu P, Zhou J, Zhang Y, Grosset J, Bishai WR, Liu JO. Methionine aminopeptidases from Mycobacterium tuberculosis as novel antimycobacterial targets. Chemistry & Biology. 17: 86-97. PMID 20142044 DOI: 10.1016/J.Chembiol.2009.12.014  0.806
2010 Schneider-Poetsch T, Ju J, Eyler DE, Dang Y, Bhat S, Merrick WC, Green R, Shen B, Liu JO. Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin. Nature Chemical Biology. 6: 209-217. PMID 20118940 DOI: 10.1038/Nchembio.304  0.825
2010 Liu H, Shi W, Luan F, Xu S, Yang F, Sun W, Liu J, Ma C. Hepatitis B virus X protein upregulates transcriptional activation of human telomerase reverse transcriptase. Virus Genes. 40: 174-82. PMID 20107884 DOI: 10.1007/s11262-009-0441-3  0.374
2010 Zhang P, Wang C, Gao K, Wang D, Mao J, An J, Xu C, Wu D, Yu H, Liu JO, Yu L. The ubiquitin ligase itch regulates apoptosis by targeting thioredoxin-interacting protein for ubiquitin-dependent degradation. The Journal of Biological Chemistry. 285: 8869-79. PMID 20068034 DOI: 10.1074/Jbc.M109.063321  0.395
2010 Liu J, Someren E, Mentink A, Licht R, Dechering K, van Blitterswijk C, de Boer J. The effect of PKC activation and inhibition on osteogenic differentiation of human mesenchymal stem cells. Journal of Tissue Engineering and Regenerative Medicine. 4: 329-39. PMID 20033927 DOI: 10.1002/term.242  0.303
2010 Cheng K, Liu J, Sun H, Xie J. Synthesis of Nucleoside Conjugates as Potential Inhibitors of Glycogen Phosphorylase Synthesis. 2010: 1046-1052. DOI: 10.1055/S-0029-1218629  0.352
2010 Schneider-Poetsch T, Ju J, Eyler DE, Dang Y, Bhat S, Merrick WC, Green R, Shen B, Liu JO. Inhibition of eukaryotic translation elongation by cycloheximide and lactimidomycin Nature Chemical Biology. 6: 209-217. DOI: 10.1038/nchembio.304  0.678
2010 Zha XM, Zhang FR, Shan JQ, Zhang YH, Liu JO, Sun HB. Synthesis and evaluation of in vitro anticancer activity of novel solasodine derivatives Chinese Chemical Letters. 21: 1087-1090. DOI: 10.1016/J.Cclet.2010.04.020  0.37
2009 Olaleye OA, Bishai WR, Liu JO. Targeting the role of N-terminal methionine processing enzymes in Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland). 89: S55-9. PMID 20006307 DOI: 10.1016/S1472-9792(09)70013-7  0.666
2009 Yang HC, Xing S, Shan L, O'Connell K, Dinoso J, Shen A, Zhou Y, Shrum CK, Han Y, Liu JO, Zhang H, Margolick JB, Siliciano RF. Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation. The Journal of Clinical Investigation. 119: 3473-86. PMID 19805909 DOI: 10.1172/Jci39199  0.366
2009 Lee K, Zhang H, Qian DZ, Rey S, Liu JO, Semenza GL. Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization. Proceedings of the National Academy of Sciences of the United States of America. 106: 17910-5. PMID 19805192 DOI: 10.1073/Pnas.0909353106  0.399
2009 Li W, Dang Y, Liu JO, Yu B. Expeditious synthesis of hippuristanol and congeners with potent antiproliferative activities. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 10356-9. PMID 19746484 DOI: 10.1002/Chem.200901732  0.668
2009 Pan F, Yu H, Dang EV, Barbi J, Pan X, Grosso JF, Jinasena D, Sharma SM, McCadden EM, Getnet D, Drake CG, Liu JO, Ostrowski MC, Pardoll DM. Eos mediates Foxp3-dependent gene silencing in CD4+ regulatory T cells. Science (New York, N.Y.). 325: 1142-6. PMID 19696312 DOI: 10.1126/Science.1176077  0.57
2009 Ji L, Shen K, Liu J, Chen Y, Liu T, Wang Z. Intracellular glutathione regulates Andrographolide-induced cytotoxicity on hepatoma Hep3B cells. Redox Report : Communications in Free Radical Research. 14: 176-84. PMID 19695125 DOI: 10.1179/135100009X466122  0.309
2009 Zhang P, Hao J, Liu J, Lu Q, Sheng H, Zhang L, Sun H. Synthesis of 3-deoxypentacyclic triterpene derivatives as inhibitors of glycogen phosphorylase. Journal of Natural Products. 72: 1414-8. PMID 19642687 DOI: 10.1021/Np9002367  0.383
2009 Woodard LE, Chang W, Chen X, Liu JO, Shapiro TA, Posner GH. Malaria-infected mice live until at least day 30 after a new monomeric trioxane combined with mefloquine are administered together in a single low oral dose Journal of Medicinal Chemistry. 52: 7458-7462. PMID 19586052 DOI: 10.1021/Jm9005934  0.511
2009 Dang Y, Low WK, Xu J, Gehring NH, Dietz HC, Romo D, Liu JO. Inhibition of nonsense-mediated mRNA decay by the natural product pateamine A through eukaryotic initiation factor 4AIII. The Journal of Biological Chemistry. 284: 23613-21. PMID 19570977 DOI: 10.1074/Jbc.M109.009985  0.749
2009 Zhang Y, Byun Y, Ren YR, Liu JO, Laterra J, Pomper MG. Identification of inhibitors of ABCG2 by a bioluminescence imaging-based high-throughput assay Cancer Research. 69: 5867-5875. PMID 19567678 DOI: 10.1158/0008-5472.Can-08-4866  0.813
2009 Zou CY, Smith KD, Zhu QS, Liu J, McCutcheon IE, Slopis JM, Meric-Bernstam F, Peng Z, Bornmann WG, Mills GB, Lazar AJ, Pollock RE, Lev D. Dual targeting of AKT and mammalian target of rapamycin: a potential therapeutic approach for malignant peripheral nerve sheath tumor. Molecular Cancer Therapeutics. 8: 1157-68. PMID 19417153 DOI: 10.1158/1535-7163.Mct-08-1008  0.353
2009 Liu JO, Nacev BA, Xu J, Bhat S. It takes two binding sites for calcineurin and NFAT to tango. Molecular Cell. 33: 676-8. PMID 19328062 DOI: 10.1016/J.Molcel.2009.03.005  0.775
2009 Cheng K, Liu J, Liu X, Li H, Sun H, Xie J. Synthesis of glucoconjugates of oleanolic acid as inhibitors of glycogen phosphorylase. Carbohydrate Research. 344: 841-50. PMID 19269628 DOI: 10.1016/j.carres.2009.02.012  0.318
2009 Chen X, Xie S, Bhat S, Kumar N, Shapiro TA, Liu JO. Fumagillin and fumarranol interact with P. falciparum methionine aminopeptidase 2 and inhibit malaria parasite growth in vitro and in vivo. Chemistry & Biology. 16: 193-202. PMID 19246010 DOI: 10.1016/J.Chembiol.2009.01.006  0.808
2009 Wikoff WR, Anfora AT, Liu J, Schultz PG, Lesley SA, Peters EC, Siuzdak G. Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proceedings of the National Academy of Sciences of the United States of America. 106: 3698-703. PMID 19234110 DOI: 10.1073/Pnas.0812874106  0.409
2009 Rosenthal AS, Chen X, Liu JO, West DC, Hergenrother PJ, Shapiro TA, Posner GH. Malaria-infected mice are cured by a single oral dose of new dimeric trioxane sulfones which are also selectively and powerfully cytotoxic to cancer cells. Journal of Medicinal Chemistry. 52: 1198-203. PMID 19186946 DOI: 10.1021/Jm801484V  0.653
2009 Lee K, Qian DZ, Rey S, Wei H, Liu JO, Semenza GL. Anthracycline chemotherapy inhibits HIF-1 transcriptional activity and tumor-induced mobilization of circulating angiogenic cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 2353-8. PMID 19168635 DOI: 10.1073/Pnas.0812801106  0.427
2008 Ren YR, Pan F, Parvez S, Fleig A, Chong CR, Xu J, Dang Y, Zhang J, Jiang H, Penner R, Liu JO. Clofazimine inhibits human Kv1.3 potassium channel by perturbing calcium oscillation in T lymphocytes. Plos One. 3: e4009. PMID 19104661 DOI: 10.1371/Journal.Pone.0004009  0.795
2008 Zhang H, Qian DZ, Tan YS, Lee K, Gao P, Ren YR, Rey S, Hammers H, Chang D, Pili R, Dang CV, Liu JO, Semenza GL. Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth Proceedings of the National Academy of Sciences of the United States of America. 105: 19579-19586. PMID 19020076 DOI: 10.1073/Pnas.0809763105  0.796
2008 Cheng K, Zhang P, Liu J, Xie J, Sun H. Practical synthesis of bredemolic acid, a natural inhibitor of glycogen phosphorylase. Journal of Natural Products. 71: 1877-80. PMID 18847277 DOI: 10.1021/Np8003886  0.314
2008 McMahon MA, Siliciano JD, Lai J, Liu JO, Stivers JT, Siliciano RF, Kohli RM. The antiherpetic drug acyclovir inhibits HIV replication and selects the V75I reverse transcriptase multidrug resistance mutation. The Journal of Biological Chemistry. 283: 31289-93. PMID 18818198 DOI: 10.1074/Jbc.C800188200  0.599
2008 Wang C, Jiang Z, Yao J, Wu X, Sun L, Liu C, Duan W, Yan M, Sun L, Liu J, Zhang L. Participation of cathepsin B in emodin-induced apoptosis in HK-2 Cells. Toxicology Letters. 181: 196-204. PMID 18789614 DOI: 10.1016/j.toxlet.2008.05.013  0.305
2008 Wang Y, Zhang F, Zhang Y, Liu JO, Ma D. Synthesis and antitumor activity of cyclodepsipeptide zygosporamide and its analogues. Bioorganic & Medicinal Chemistry Letters. 18: 4385-7. PMID 18606540 DOI: 10.1016/J.Bmcl.2008.06.066  0.674
2008 Wen X, Sun H, Liu J, Cheng K, Zhang P, Zhang L, Hao J, Zhang L, Ni P, Zographos SE, Leonidas DD, Alexacou KM, Gimisis T, Hayes JM, Oikonomakos NG. Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies. Journal of Medicinal Chemistry. 51: 3540-54. PMID 18517260 DOI: 10.1021/Jm8000949  0.423
2008 Pei Y, Zhu P, Dang Y, Wu J, Yang X, Wan B, Liu JO, Yi Q, Yu L. Nuclear export of NF90 to stabilize IL-2 mRNA is mediated by AKT-dependent phosphorylation at Ser647 in response to CD28 costimulation. Journal of Immunology (Baltimore, Md. : 1950). 180: 222-9. PMID 18097023 DOI: 10.4049/Jimmunol.180.1.222  0.621
2008 Galbán S, Kuwano Y, Pullmann R, Martindale JL, Kim HH, Lal A, Abdelmohsen K, Yang X, Dang Y, Liu JO, Lewis SM, Holcik M, Gorospe M. RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha. Molecular and Cellular Biology. 28: 93-107. PMID 17967866 DOI: 10.1128/Mcb.00973-07  0.312
2008 Liu J, Shi YH, Yin J, Gui JF. [Screen of differentially expressed genes between gastrula embryos and tail bud embryos in gynogenetic gibel carp (Carassius auratus gibelio)]. Yi Chuan Xue Bao = Acta Genetica Sinica. 32: 253-63. PMID 15931786  0.314
2007 Liu YV, Hubbi ME, Pan F, McDonald KR, Mansharamani M, Cole RN, Liu JO, Semenza GL. Calcineurin promotes hypoxia-inducible factor 1alpha expression by dephosphorylating RACK1 and blocking RACK1 dimerization. The Journal of Biological Chemistry. 282: 37064-73. PMID 17965024 DOI: 10.1074/Jbc.M705015200  0.573
2007 Yin J, Xia JH, Du XZ, Liu J, Zhou L, Hong YH, Gui JF. Developmental expression of CagMdkb during gibel carp embryogenesis. The International Journal of Developmental Biology. 51: 761-9. PMID 17939124 DOI: 10.1387/ijdb.072346jy  0.332
2007 Hu XV, Chen X, Han KC, Mildvan AS, Liu JO. Kinetic and mutational studies of the number of interacting divalent cations required by bacterial and human methionine aminopeptidases. Biochemistry. 46: 12833-43. PMID 17929833 DOI: 10.1021/Bi701127X  0.651
2007 Low WK, Dang Y, Schneider-Poetsch T, Shi Z, Choi NS, Rzasa RM, Shea HA, Li S, Park K, Ma G, Romo D, Liu JO. Isolation and identification of eukaryotic initiation factor 4A as a molecular target for the marine natural product Pateamine A. Methods in Enzymology. 431: 303-24. PMID 17923240 DOI: 10.1016/S0076-6879(07)31014-8  0.812
2007 Ji L, Liu T, Liu J, Chen Y, Wang Z. Andrographolide inhibits human hepatoma-derived Hep3B cell growth through the activation of c-Jun N-terminal kinase. Planta Medica. 73: 1397-401. PMID 17918040 DOI: 10.1055/s-2007-990230  0.32
2007 Peddibhotla S, Dang Y, Liu JO, Romo D. Simultaneous arming and structure/activity studies of natural products employing O-H insertions: an expedient and versatile strategy for natural products-based chemical genetics. Journal of the American Chemical Society. 129: 12222-31. PMID 17880073 DOI: 10.1021/Ja0733686  0.723
2007 Byrne ST, Gu P, Zhou J, Denkin SM, Chong C, Sullivan D, Liu JO, Zhang Y. Pyrrolidine dithiocarbamate and diethyldithiocarbamate are active against growing and nongrowing persister Mycobacterium tuberculosis. Antimicrobial Agents and Chemotherapy. 51: 4495-7. PMID 17876006 DOI: 10.1128/Aac.00753-07  0.699
2007 Peng W, Tang P, Hu X, Liu JO, Yu B. Synthesis of the A,B-ring-truncated OSW saponin analogs and their antitumor activities. Bioorganic & Medicinal Chemistry Letters. 17: 5506-9. PMID 17826089 DOI: 10.1016/J.Bmcl.2007.08.060  0.568
2007 Hu X, Dang Y, Tenney K, Crews P, Tsai CW, Sixt KM, Cole PA, Liu JO. Regulation of c-Src Nonreceptor Tyrosine Kinase Activity by Bengamide A through Inhibition of Methionine Aminopeptidases Chemistry and Biology. 14: 764-774. PMID 17656313 DOI: 10.1016/J.Chembiol.2007.05.010  0.767
2007 Zhao Q, Liu Z, Wang Z, Yang C, Liu J, Lu J. Effect of prepro-calcitonin gene-related peptide-expressing endothelial progenitor cells on pulmonary hypertension. The Annals of Thoracic Surgery. 84: 544-52. PMID 17643632 DOI: 10.1016/J.ATHORACSUR.2007.03.067  0.318
2007 Low WK, Dang Y, Bhat S, Romo D, Liu JO. Substrate-dependent targeting of eukaryotic translation initiation factor 4A by pateamine A: negation of domain-linker regulation of activity. Chemistry & Biology. 14: 715-27. PMID 17584618 DOI: 10.1016/J.Chembiol.2007.05.012  0.809
2007 McMahon MA, Jilek BL, Brennan TP, Shen L, Zhou Y, Wind-Rotolo M, Xing S, Bhat S, Hale B, Hegarty R, Chong CR, Liu JO, Siliciano RF, Thio CL. The HBV drug entecavir - effects on HIV-1 replication and resistance. The New England Journal of Medicine. 356: 2614-21. PMID 17582071 DOI: 10.1056/Nejmoa067710  0.769
2007 Chong CR, Xu J, Lu J, Bhat S, Sullivan DJ, Liu JO. Inhibition of angiogenesis by the antifungal drug itraconazole. Acs Chemical Biology. 2: 263-70. PMID 17432820 DOI: 10.1021/Cb600362D  0.826
2007 Fang K, Fu W, Beardsley AR, Sun X, Lisanti MP, Liu J. Overexpression of caveolin-1 inhibits endothelial cell proliferation by arresting the cell cycle at G0/G1 phase. Cell Cycle (Georgetown, Tex.). 6: 199-204. PMID 17245131 DOI: 10.4161/Cc.6.2.3740  0.318
2007 Pan F, Sun L, Kardian DB, Whartenby KA, Pardoll DM, Liu JO. Feedback inhibition of calcineurin and Ras by a dual inhibitory protein Carabin. Nature. 445: 433-6. PMID 17230191 DOI: 10.1038/Nature05476  0.804
2007 Tang P, Mamdani F, Hu X, Liu JO, Yu B. Synthesis of OSW saponin analogs with modified sugar residues and their antiproliferative activities. Bioorganic & Medicinal Chemistry Letters. 17: 1003-7. PMID 17127060 DOI: 10.1016/J.Bmcl.2006.11.032  0.581
2007 Hu X, Mildvan AS, Liu JO. Cooperative activation of human mitochondrial Methionine Aminopeptidase (hmMetAP) by Co2+ The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A272-B  0.443
2006 Allen MD, DiPilato LM, Rahdar M, Ren YR, Chong C, Liu JO, Zhang J. Reading dynamic kinase activity in living cells for high-throughput screening. Acs Chemical Biology. 1: 371-6. PMID 17163774 DOI: 10.1021/Cb600202F  0.807
2006 Hu X, Addlagatta A, Lu J, Matthews BW, Liu JO. Elucidation of the function of type 1 human methionine aminopeptidase during cell cycle progression. Proceedings of the National Academy of Sciences of the United States of America. 103: 18148-53. PMID 17114291 DOI: 10.1073/Pnas.0608389103  0.639
2006 Zhou M, Sivaramakrishnan A, Ponnamperuma K, Low WK, Li C, Liu JO, Bergbreiter DE, Romo D. Synthesis, characterization, and utility of thermoresponsive natural/unnatural product macroligands for affinity chromatography. Organic Letters. 8: 5247-50. PMID 17078689 DOI: 10.1021/Ol062045W  0.582
2006 Chen X, Chong CR, Shi L, Yoshimoto T, Sullivan DJ, Liu JO. Inhibitors of Plasmodium falciparum methionine aminopeptidase 1b possess antimalarial activity. Proceedings of the National Academy of Sciences of the United States of America. 103: 14548-53. PMID 16983082 DOI: 10.1073/Pnas.0604101103  0.798
2006 Lu J, Chong CR, Hu X, Liu JO. Fumarranol, a rearranged fumagillin analogue that inhibits angiogenesis in vivo. Journal of Medicinal Chemistry. 49: 5645-8. PMID 16970390 DOI: 10.1021/Jm060559V  0.826
2006 Dang Y, Kedersha N, Low WK, Romo D, Gorospe M, Kaufman R, Anderson P, Liu JO. Eukaryotic initiation factor 2alpha-independent pathway of stress granule induction by the natural product pateamine A. The Journal of Biological Chemistry. 281: 32870-8. PMID 16951406 DOI: 10.1074/Jbc.M606149200  0.701
2006 Kim H, Kim BY, Soh JW, Cho EJ, Liu JO, Youn HD. A novel function of Nur77: physical and functional association with protein kinase C. Biochemical and Biophysical Research Communications. 348: 950-6. PMID 16904076 DOI: 10.1016/J.Bbrc.2006.07.167  0.663
2006 Ma D, Zou B, Cai G, Hu X, Liu JO. Total synthesis of the cyclodepsipeptide apratoxin A and its analogues and assessment of their biological activities. Chemistry (Weinheim An Der Bergstrasse, Germany). 12: 7615-26. PMID 16832801 DOI: 10.1002/Chem.200600599  0.595
2006 Chong CR, Chen X, Shi L, Liu JO, Sullivan DJ. A clinical drug library screen identifies astemizole as an antimalarial agent. Nature Chemical Biology. 2: 415-6. PMID 16816845 DOI: 10.1038/Nchembio806  0.772
2006 Hu X, Addlagatta A, Matthews BW, Liu JO. Identification of pyridinylpyrimidines as inhibitors of human methionine aminopeptidases. Angewandte Chemie (International Ed. in English). 45: 3772-5. PMID 16724298 DOI: 10.1002/Anie.200600757  0.575
2006 Chong CR, Qian DZ, Pan F, Wei Y, Pili R, Sullivan DJ, Liu JO. Identification of type 1 inosine monophosphate dehydrogenase as an antiangiogenic drug target. Journal of Medicinal Chemistry. 49: 2677-80. PMID 16640327 DOI: 10.1021/Jm051225T  0.813
2006 Hu X, Addlagatta A, Matthews BW, Liu JO. Cover Picture: Identification of Pyridinylpyrimidines as Inhibitors of Human Methionine Aminopeptidases (Angew. Chem. Int. Ed. 23/2006) Angewandte Chemie International Edition. 45: 3717-3717. DOI: 10.1002/Anie.200690079  0.547
2006 Hu X, Addlagatta A, Matthews BW, Liu JO. Titelbild: Identification of Pyridinylpyrimidines as Inhibitors of Human Methionine Aminopeptidases (Angew. Chem. 23/2006) Angewandte Chemie. 118: 3801-3801. DOI: 10.1002/Ange.200690079  0.549
2005 Low WK, Dang Y, Schneider-Poetsch T, Shi Z, Choi NS, Merrick WC, Romo D, Liu JO. Inhibition of eukaryotic translation initiation by the marine natural product pateamine A. Molecular Cell. 20: 709-22. PMID 16337595 DOI: 10.1016/J.Molcel.2005.10.008  0.821
2005 Shi B, Tang P, Hu X, Liu JO, Yu B. OSW saponins: facile synthesis toward a new type of structures with potent antitumor activities. The Journal of Organic Chemistry. 70: 10354-67. PMID 16323845 DOI: 10.1021/Jo051536B  0.562
2005 Addlagatta A, Hu X, Liu JO, Matthews BW. Structural basis for the functional differences between type I and type II human methionine aminopeptidases. Biochemistry. 44: 14741-9. PMID 16274222 DOI: 10.1021/Bi051691K  0.573
2005 Burguière A, Hitchen PG, Dover LG, Kremer L, Ridell M, Alexander DC, Liu J, Morris HR, Minnikin DE, Dell A, Besra GS. LosA, a key glycosyltransferase involved in the biosynthesis of a novel family of glycosylated acyltrehalose lipooligosaccharides from Mycobacterium marinum. The Journal of Biological Chemistry. 280: 42124-33. PMID 16257960 DOI: 10.1074/Jbc.M507500200  0.323
2005 Pan F, Means AR, Liu JO. Calmodulin-dependent protein kinase IV regulates nuclear export of Cabin1 during T-cell activation. The Embo Journal. 24: 2104-13. PMID 15902271 DOI: 10.1038/Sj.Emboj.7600685  0.607
2005 Addlagatta A, Quillin ML, Omotoso O, Liu JO, Matthews BW. Identification of an SH3-binding motif in a new class of methionine aminopeptidases from Mycobacterium tuberculosis suggests a mode of interaction with the ribosome. Biochemistry. 44: 7166-74. PMID 15882055 DOI: 10.1021/Bi0501176  0.342
2005 Wang S, Dong Y, Wang X, Hu X, Liu JO, Hu Y. 3-Aryl beta-carbolin-1-ones as a new class of potent inhibitors of tumor cell proliferation: synthesis and biological evaluation. Organic & Biomolecular Chemistry. 3: 911-6. PMID 15731878 DOI: 10.1039/B412921K  0.581
2005 Liu J, Wu X, Mitchell B, Kintner C, Ding S, Schultz PG. A small-molecule agonist of the Wnt signaling pathway. Angewandte Chemie (International Ed. in English). 44: 1987-90. PMID 15724259 DOI: 10.1002/Anie.200462552  0.39
2005 Liu J, Bang AG, Kintner C, Orth AP, Chanda SK, Ding S, Schultz PG. Identification of the Wnt signaling activator leucine-rich repeat in Flightless interaction protein 2 by a genome-wide functional analysis. Proceedings of the National Academy of Sciences of the United States of America. 102: 1927-32. PMID 15677333 DOI: 10.1073/Pnas.0409472102  0.451
2005 Liu JO. The yins of T cell activation. Science's Stke : Signal Transduction Knowledge Environment. 2005: re1. PMID 15632417 DOI: 10.1126/stke.2652005re1  0.304
2005 Han A, He J, Wu Y, Liu JO, Chen L. Mechanism of recruitment of class II histone deacetylases by myocyte enhancer factor-2. Journal of Molecular Biology. 345: 91-102. PMID 15567413 DOI: 10.1016/J.Jmb.2004.10.033  0.348
2004 Boxem M, Tsai CW, Zhang Y, Saito RM, Liu JO. The C. elegans methionine aminopeptidase 2 analog map-2 is required for germ cell proliferation. Febs Letters. 576: 245-50. PMID 15474045 DOI: 10.1016/J.Febslet.2004.08.077  0.341
2004 Romo D, Choi NS, Li S, Buchler I, Shi Z, Liu JO. Evidence for separate binding and scaffolding domains in the immunosuppressive and antitumor marine natural product, pateamine a: design, synthesis, and activity studies leading to a potent simplified derivative. Journal of the American Chemical Society. 126: 10582-8. PMID 15327314 DOI: 10.1021/Ja040065S  0.608
2004 Wang S, Sun J, Yu G, Hu X, Liu JO, Hu Y. CuI catalyzed N-arylation of amide as a key step for the preparation of 3-aryl beta-carbolin-1-ones. Organic & Biomolecular Chemistry. 2: 1573-4. PMID 15162205 DOI: 10.1039/B406046F  0.468
2004 Lu SC, Yan LN, Li B, Wen TF, Zhao JC, Cheng NS, Liu C, Liu J, Wang XB, Li XD, Qin S, Zhao LS, Lei BJ, Zhang XH. Lamivudine prophylaxis of liver allograft HBV reinfection in HBV related cirrhotic patients after liver transplantation. Hepatobiliary & Pancreatic Diseases International : Hbpd Int. 3: 26-32. PMID 14969833  0.332
2004 Alexander DC, Jones JR, Tan T, Chen JM, Liu J. PimF, a mannosyltransferase of mycobacteria, is involved in the biosynthesis of phosphatidylinositol mannosides and lipoarabinomannan. The Journal of Biological Chemistry. 279: 18824-33. PMID 14960574 DOI: 10.1074/Jbc.M400791200  0.375
2004 Choi JW, Park SC, Kang GH, Liu JO, Youn HD. Nur77 activated by hypoxia-inducible factor-1alpha overproduces proopiomelanocortin in von Hippel-Lindau-mutated renal cell carcinoma. Cancer Research. 64: 35-9. PMID 14729605 DOI: 10.1158/0008-5472.Can-03-0145  0.631
2004 Pan F, Ye Z, Cheng L, Liu JO. Myocyte enhancer factor 2 mediates calcium-dependent transcription of the interleukin-2 gene in T lymphocytes: a calcium signaling module that is distinct from but collaborates with the nuclear factor of activated T cells (NFAT). The Journal of Biological Chemistry. 279: 14477-80. PMID 14722108 DOI: 10.1074/Jbc.C300487200  0.598
2004 Zheng L, Liu J, Batalov S, Zhou D, Orth A, Ding S, Schultz PG. An approach to genomewide screens of expressed small interfering RNAs in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 135-40. PMID 14688408 DOI: 10.1073/Pnas.2136685100  0.424
2003 Liu JO. Endogenous protein inhibitors of calcineurin. Biochemical and Biophysical Research Communications. 311: 1103-9. PMID 14623296 DOI: 10.1016/J.Bbrc.2003.10.020  0.407
2003 Kim H, Lee JE, Cho EJ, Liu JO, Youn HD. Menin, a tumor suppressor, represses JunD-mediated transcriptional activity by association with an mSin3A-histone deacetylase complex. Cancer Research. 63: 6135-9. PMID 14559791  0.595
2003 Zhou G, Tsai CW, Liu JO. Fumagalone, a reversible inhibitor of type 2 methionine aminopeptidase and angiogenesis. Journal of Medicinal Chemistry. 46: 3452-4. PMID 12877582 DOI: 10.1021/Jm0341103  0.412
2003 Nezami A, Kimura T, Hidaka K, Kiso A, Liu J, Kiso Y, Goldberg DE, Freire E. High-affinity inhibition of a family of Plasmodium falciparum proteases by a designed adaptive inhibitor. Biochemistry. 42: 8459-64. PMID 12859191 DOI: 10.1021/Bi034131Z  0.335
2003 He H, Dang Y, Dai F, Guo Z, Wu J, She X, Pei Y, Chen Y, Ling W, Wu C, Zhao S, Liu JO, Yu L. Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B. The Journal of Biological Chemistry. 278: 29278-87. PMID 12740394 DOI: 10.1074/Jbc.M303800200  0.634
2003 Han A, Pan F, Stroud JC, Youn HD, Liu JO, Chen L. Sequence-specific recruitment of transcriptional co-repressor Cabin1 by myocyte enhancer factor-2. Nature. 422: 730-4. PMID 12700764 DOI: 10.1038/Nature01555  0.731
2003 Visner GA, Lu F, Zhou H, Liu J, Kazemfar K, Agarwal A. Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: implications in the antiproliferative response to rapamycin. Circulation. 107: 911-6. PMID 12591764 DOI: 10.1161/01.Cir.0000048191.75585.60  0.305
2003 Guo WZ, Ran YL, Liu J, Yu L, Sun LX, Yang ZH. [High expression of human angiogenesis inhibitor HIAF-1 in insect cells and biological activity]. Ai Zheng = Aizheng = Chinese Journal of Cancer. 21: 245-8. PMID 12451987  0.328
2002 Huai Q, Kim HY, Liu Y, Zhao Y, Mondragon A, Liu JO, Ke H. Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes. Proceedings of the National Academy of Sciences of the United States of America. 99: 12037-42. PMID 12218175 DOI: 10.1073/Pnas.192206699  0.754
2002 Kim MJ, Jo DG, Hong GS, Kim BJ, Lai M, Cho DH, Kim KW, Bandyopadhyay A, Hong YM, Kim DH, Cho C, Liu JO, Snyder SH, Jung YK. Calpain-dependent cleavage of cain/cabin1 activates calcineurin to mediate calcium-triggered cell death. Proceedings of the National Academy of Sciences of the United States of America. 99: 9870-5. PMID 12114545 DOI: 10.1073/Pnas.152336999  0.397
2002 Smulik JA, Diver ST, Pan F, Liu JO. Synthesis of cyclosporin A-derived affinity reagents by olefin metathesis. Organic Letters. 4: 2051-4. PMID 12049515 DOI: 10.1021/Ol0258987  0.704
2001 Esau C, Boes M, Youn HD, Tatterson L, Liu JO, Chen J. Deletion of calcineurin and myocyte enhancer factor 2 (MEF2) binding domain of Cabin1 results in enhanced cytokine gene expression in T cells Journal of Experimental Medicine. 194: 1449-1459. PMID 11714752 DOI: 10.1084/Jem.194.10.1449  0.621
2001 Baumgrass R, Weiwad M, Erdmann F, Liu JO, Wunderlich D, Grabley S, Fischer G. Reversible Inhibition of Calcineurin by the Polyphenolic Aldehyde Gossypol Journal of Biological Chemistry. 276: 47914-47921. PMID 11598106 DOI: 10.1074/Jbc.M103273200  0.436
2001 Zhang LH, Youn HD, Liu JO. Inhibition of Cell Cycle Progression by the Novel Cyclophilin Ligand Sanglifehrin A Is Mediated through the NFκB-dependent Activation of p53 Journal of Biological Chemistry. 276: 43534-43540. PMID 11557753 DOI: 10.1074/Jbc.M104257200  0.666
2001 Liu W, Youn HD, Liu JO. Thapsigargin-induced apoptosis involves Cabin1-MEF2-mediated induction of Nur77 European Journal of Immunology. 31: 1757-1764. PMID 11385620 DOI: 10.1002/1521-4141(200106)31:6<1757::Aid-Immu1757>3.0.Co;2-J  0.709
2001 Liu W, Youn HD, Zhou XZ, Lu KP, Liu JO. Binding and regulation of the transcription factor NFAT by the peptidyl prolyl cis-trans isomerase Pin1 Febs Letters. 496: 105-108. PMID 11356192 DOI: 10.1016/S0014-5793(01)02411-5  0.717
2001 Zhang LH, Liu JO. Sanglifehrin A, a novel cyclophilin-binding immunosuppressant, inhibits IL-2-dependent T cell proliferation at the G1 phase of the cell cycle Journal of Immunology. 166: 5611-5618. PMID 11313401 DOI: 10.4049/Jimmunol.166.9.5611  0.763
2000 Youn HD, Chatila TA, Liu JO. Integration of calcineurin and MEF2 signals by the coactivator p300 during T-cell apoptosis Embo Journal. 19: 4323-4331. PMID 10944115 DOI: 10.1093/Emboj/19.16.4323  0.644
2000 Youn HD, Liu JO. Cabin1 represses MEF2-dependent Nur77 expression and T cell apoptosis by controlling association of histone deacetylases and acetylases with MEF2 Immunity. 13: 85-94. PMID 10933397 DOI: 10.1016/S1074-7613(00)00010-8  0.608
2000 Zhang Y, Griffith EC, Sage J, Jacks T, Liu JO. Cell cycle inhibition by the anti-angiogenic agent TNP-470 is mediated by p53 and p21WAF1/CIP1. Proceedings of the National Academy of Sciences of the United States of America. 97: 6427-32. PMID 10841547 DOI: 10.1073/Pnas.97.12.6427  0.4
2000 Youn HD, Grozinger CM, Liu JO. Calcium regulates transcriptional repression of myocyte enhancer factor 2 by histone deacetylase 4. The Journal of Biological Chemistry. 275: 22563-7. PMID 10825153 DOI: 10.1074/Jbc.C000304200  0.712
2000 Dai X, Su Z, Liu JO. An improved synthesis of a selective αvβ3-integrin antagonist cyclo(-RGDfK-) Tetrahedron Letters. 41: 6295-6298.  0.746
1999 Turk BE, Griffith EC, Wolf S, Biemann K, Chang YH, Liu JO. Selective inhibition of amino-terminal methionine processing by TNP-470 and ovalicin in endothelial cells. Chemistry & Biology. 6: 823-33. PMID 10574784 DOI: 10.1016/S1074-5521(99)80129-X  0.642
1999 Youn HD, Sun L, Prywes R, Liu JO. Apoptosis of T cells mediated by Ca2+-induced release of the transcription factor MEF2. Science (New York, N.Y.). 286: 790-3. PMID 10531067 DOI: 10.1126/Science.286.5440.790  0.793
1998 Niwayama S, Loh C, Turk BE, Liu JO, Miyachi H, Hashimoto Y. Enhanced potency of perfluorinated thalidomide derivatives for inhibition of LPS-induced tumor necrosis factor-α production is associated with a change of mechanism of action Bioorganic and Medicinal Chemistry Letters. 8: 1071-1076. PMID 9871710 DOI: 10.1016/S0960-894X(98)00171-1  0.799
1998 Griffith EC, Zhuang SU, Niwayama S, Ramsay CA, Chang YH, Liu JO. Molecular recognition of angiogenesis inhibitors fumagillin and ovalicin by methionine aminopeptidase 2 Proceedings of the National Academy of Sciences of the United States of America. 95: 15183-15188. PMID 9860943 DOI: 10.1073/Pnas.95.26.15183  0.699
1998 Turk BE, Su Z, Liu JO. Synthetic analogues of TNP-470 and ovalicin reveal a common molecular basis for inhibition of angiogenesis and immunosuppression Bioorganic and Medicinal Chemistry. 6: 1163-1169. PMID 9784858 DOI: 10.1016/S0968-0896(98)00078-9  0.843
1998 Miyachi H, Koiso Y, Shirai R, Niwayama S, Liu JO, Hashimoto Y. Tumor necrosis factor-alpha production enhancing activity of substituted 3'-methylthalidomide: Influence of substituents at the phthaloyl moiety on the activity and stereoselectivity Chemical and Pharmaceutical Bulletin. 46: 1165-1168. PMID 9692223 DOI: 10.1248/Cpb.46.1165  0.624
1998 Sun L, Youn HD, Loh C, Stolow M, He W, Liu JO. Cabin 1, a negative regulator for calcineurin signaling in T lymphocytes Immunity. 8: 703-711. PMID 9655484 DOI: 10.1016/S1074-7613(00)80575-0  0.813
1998 Romo D, Rzasa RM, Shea HA, Park K, Langenhan JM, Sun L, Akhiezer A, Liu JO. Total synthesis and immunosuppressive activity of (-)-pateamine A and related compounds: Implementation of a β-lactam-based macrocyclization Journal of the American Chemical Society. 120: 12237-12254. DOI: 10.1021/Ja981846U  0.552
1997 Jiang H, Xiong F, Kong S, Ogawa T, Kobayashi M, Liu JO. Distinct tissue and cellular distribution of two major isoforms of calcineurin Molecular Immunology. 34: 663-669. PMID 9393969 DOI: 10.1016/S0161-5890(97)00054-0  0.333
1997 Griffith EC, Su Z, Turk BE, Chen S, Chang YH, Wu Z, Biemann K, Liu JO. Methionine aminopeptidase (type 2) is the common target for angiogenesis inhibitors AGM-1470 and ovalicin. Chemistry & Biology. 4: 461-71. PMID 9224570 DOI: 10.1016/S1074-5521(97)90198-8  0.848
1997 Mondragon A, Griffith EC, Sun L, Xiong F, Armstrong C, Liu JO. Overexpression and purification of human calcineurin alpha from Escherichia coli and assessment of catalytic functions of residues surrounding the binuclear metal center. Biochemistry. 36: 4934-42. PMID 9125515 DOI: 10.1021/Bi9631935  0.731
1996 Niwayama S, Turk BE, Liu JO. Potent inhibition of tumor necrosis factor-α production by tetrafluorothalidomide and tetrafluorophthalimides Journal of Medicinal Chemistry. 39: 3044-3045. PMID 8759624 DOI: 10.1021/Jm960284R  0.73
1996 Turk BE, Jiang H, Liu JO. Binding of thalidomide to α1-acid glycoprotein may be involved in its inhibition of tumor necrosis factor α production Proceedings of the National Academy of Sciences of the United States of America. 93: 7552-7556. PMID 8755512 DOI: 10.1073/Pnas.93.15.7552  0.62
1994 Liu J. Microcin B17: Posttranslational modifications and their biological implications Proceedings of the National Academy of Sciences of the United States of America. 91: 4618-4620. PMID 8197107 DOI: 10.1073/Pnas.91.11.4618  0.351
1993 Liu J. FK506 and ciclosporin: molecular probes for studying intracellular signal transduction Trends in Pharmacological Sciences. 14: 182-188. PMID 7692652 DOI: 10.1016/0165-6147(93)90206-Y  0.379
1992 Liu J, Albers MW, Wandless TJ, Luan S, Alberg DG, Belshaw PJ, Cohen P, MacKintosh C, Klee CB, Schreiber SL. Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity. Biochemistry. 31: 3896-901. PMID 1373650 DOI: 10.1021/Bi00131A002  0.813
1991 Liu J, Farmer JD, Lane WS, Friedman J, Weissman I, Schreiber SL. Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell. 66: 807-15. PMID 1715244 DOI: 10.1016/0092-8674(91)90124-H  0.514
1990 Liu J, Albers MW, Chen CM, Schreiber SL, Walsh CT. Cloning, expression, and purification of human cyclophilin in Escherichia coli and assessment of the catalytic role of cysteines by site-directed mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. 87: 2304-8. PMID 2179953 DOI: 10.1073/Pnas.87.6.2304  0.577
1990 Liu J, Quinn N, Berchtold GA, Walsh CT. Overexpression, purification, and characterization of isochorismate synthase (EntC), the first enzyme involved in the biosynthesis of enterobactin from chorismate. Biochemistry. 29: 1417-25. PMID 2139795 DOI: 10.1021/Bi00458A012  0.433
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