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Giovanni Stracquadanio, Ph.D. - Publications

Affiliations: 
2006-2010 Dipartimento di Matematica e Informatica Universita di Catania 
 2010-2014 Department of Biomedical Engineering Johns Hopkins University, Baltimore, MD 
 2014- Ludwig Institute for Cancer Research University of Oxford, Oxford, United Kingdom 
Area:
Computational Biology
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25 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Vegh P, Donovan S, Rosser S, Stracquadanio G, Fragkoudis R. Biofoundry-Scale DNA Assembly Validation Using Cost-Effective High-Throughput Long-Read Sequencing. Acs Synthetic Biology. 13: 683-686. PMID 38329009 DOI: 10.1021/acssynbio.3c00589  0.308
2023 Williams TC, Kroukamp H, Xu X, Wightman ELI, Llorente B, Borneman AR, Carpenter AC, Van Wyk N, Meier F, Collier TRV, Espinosa MI, Daniel EL, Walker RSK, Cai Y, Nevalainen HKM, ... ... Stracquadanio G, et al. Parallel laboratory evolution and rational debugging reveal genomic plasticity to synthetic chromosome XIV defects. Cell Genomics. 3: 100379. PMID 38020977 DOI: 10.1016/j.xgen.2023.100379  0.774
2023 McCulloch LH, Sambasivam V, Hughes AL, Annaluru N, Ramalingam S, Fanfani V, Lobzaev E, Mitchell LA, Cai J, Jiang H, LaCava J, Taylor MS, Bishai WR, Stracquadanio G, Steinmetz LM, et al. Consequences of a telomerase-related fitness defect and chromosome substitution technology in yeast strains. Cell Genomics. 3: 100419. PMID 38020974 DOI: 10.1016/j.xgen.2023.100419  0.743
2023 Blount BA, Lu X, Driessen MRM, Jovicevic D, Sanchez MI, Ciurkot K, Zhao Y, Lauer S, McKiernan RM, Gowers GF, Sweeney F, Fanfani V, Lobzaev E, Palacios-Flores K, Walker RSK, ... ... Stracquadanio G, et al. Synthetic yeast chromosome XI design provides a testbed for the study of extrachromosomal circular DNA dynamics. Cell Genomics. 3: 100418. PMID 38020971 DOI: 10.1016/j.xgen.2023.100418  0.758
2023 Foo JL, Kitano S, Susanto AV, Jin Z, Lin Y, Luo Z, Huang L, Liang Z, Mitchell LA, Yang K, Wong A, Cai Y, Cai J, Stracquadanio G, Bader JS, et al. Establishing chromosomal design-build-test-learn through a synthetic chromosome and its combinatorial reconfiguration. Cell Genomics. 3: 100435. PMID 38020970 DOI: 10.1016/j.xgen.2023.100435  0.751
2023 Lauer S, Luo J, Lazar-Stefanita L, Zhang W, McCulloch LH, Fanfani V, Lobzaev E, Haase MAB, Easo N, Zhao Y, Yu F, Cai J, Bader JS, Stracquadanio G, Boeke JD. Context-dependent neocentromere activity in synthetic yeast chromosome . Cell Genomics. 3: 100437. PMID 38020969 DOI: 10.1016/j.xgen.2023.100437  0.776
2023 Luo J, Vale-Silva LA, Raghavan AR, Mercy G, Heldrich J, Sun X, Li MK, Zhang W, Agmon N, Yang K, Cai J, Stracquadanio G, Thierry A, Zhao Y, Coelho C, et al. Synthetic chromosome fusion: Effects on mitotic and meiotic genome structure and function. Cell Genomics. 3: 100439. PMID 38020967 DOI: 10.1016/j.xgen.2023.100439  0.765
2023 Zhang W, Lazar-Stefanita L, Yamashita H, Shen MJ, Mitchell LA, Kurasawa H, Lobzaev E, Fanfani V, Haase MAB, Sun X, Jiang Q, Goldberg GW, Ichikawa DM, Lauer SL, McCulloch LH, ... ... Stracquadanio G, et al. Manipulating the 3D organization of the largest synthetic yeast chromosome. Molecular Cell. PMID 37944526 DOI: 10.1016/j.molcel.2023.10.015  0.768
2023 Zhao Y, Coelho C, Hughes AL, Lazar-Stefanita L, Yang S, Brooks AN, Walker RSK, Zhang W, Lauer S, Hernandez C, Cai J, Mitchell LA, Agmon N, Shen Y, Sall J, ... ... Stracquadanio G, et al. Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions. Cell. PMID 37944511 DOI: 10.1016/j.cell.2023.09.025  0.776
2021 Stracquadanio G, Zulkower V. Computer Aided Assembly and Verification of Synthetic Chromosomes. Methods in Molecular Biology (Clifton, N.J.). 2189: 169-181. PMID 33180301 DOI: 10.1007/978-1-0716-0822-7_13  0.535
2019 Ostrov N, Beal J, Ellis T, Gordon DB, Karas BJ, Lee HH, Lenaghan SC, Schloss JA, Stracquadanio G, Trefzer A, Bader JS, Church GM, Coelho CM, Efcavitch JW, Güell M, et al. Technological challenges and milestones for writing genomes. Science (New York, N.Y.). 366: 310-312. PMID 31624201 DOI: 10.1126/Science.Aay0339  0.604
2017 Richardson SM, Mitchell LA, Stracquadanio G, Yang K, Dymond JS, DiCarlo JE, Lee D, Huang CL, Chandrasegaran S, Cai Y, Boeke JD, Bader JS. Design of a synthetic yeast genome. Science (New York, N.Y.). 355: 1040-1044. PMID 28280199 DOI: 10.1126/Science.Aaf4557  0.807
2017 Mitchell LA, Wang A, Stracquadanio G, Kuang Z, Wang X, Yang K, Richardson S, Martin JA, Zhao Y, Walker R, Luo Y, Dai H, Dong K, Tang Z, Yang Y, et al. Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond. Science (New York, N.Y.). 355. PMID 28280154 DOI: 10.1126/Science.Aaf4831  0.773
2017 Shen Y, Wang Y, Chen T, Gao F, Gong J, Abramczyk D, Walker R, Zhao H, Chen S, Liu W, Luo Y, Müller CA, Paul-Dubois-Taine A, Alver B, Stracquadanio G, et al. Deep functional analysis of synII, a 770-kilobase synthetic yeast chromosome. Science (New York, N.Y.). 355. PMID 28280153 DOI: 10.1126/Science.Aaf4791  0.769
2017 Wu Y, Li BZ, Zhao M, Mitchell LA, Xie ZX, Lin QH, Wang X, Xiao WH, Wang Y, Zhou X, Liu H, Li X, Ding MZ, Liu D, Zhang L, ... ... Stracquadanio G, et al. Bug mapping and fitness testing of chemically synthesized chromosome X. Science (New York, N.Y.). 355. PMID 28280152 DOI: 10.1126/Science.Aaf4706  0.758
2017 Xie ZX, Li BZ, Mitchell LA, Wu Y, Qi X, Jin Z, Jia B, Wang X, Zeng BX, Liu HM, Wu XL, Feng Q, Zhang WZ, Liu W, Ding MZ, ... ... Stracquadanio G, et al. "Perfect" designer chromosome V and behavior of a ring derivative. Science (New York, N.Y.). 355. PMID 28280151 DOI: 10.1126/Science.Aaf4704  0.786
2017 Agmon N, Tang Z, Yang K, Sutter B, Ikushima S, Cai Y, Caravelli K, Martin JA, Sun X, Choi WJ, Zhang A, Stracquadanio G, Hao H, Tu BP, Fenyo D, et al. Low escape-rate genome safeguards with minimal molecular perturbation of Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. PMID 28174266 DOI: 10.1073/Pnas.1621250114  0.657
2016 Stracquadanio G, Yang K, Boeke JD, Bader JS. BioPartsDB: a synthetic biology workflow web-application for education and research. Bioinformatics (Oxford, England). PMID 27412090 DOI: 10.1093/Bioinformatics/Btw394  0.636
2015 Yang K, Stracquadanio G, Luo J, Boeke JD, Bader JS. BioPartsBuilder: a synthetic biology tool for combinatorial assembly of biological parts. Bioinformatics (Oxford, England). PMID 26568632 DOI: 10.1093/Bioinformatics/Btv664  0.664
2015 Shen Y, Stracquadanio G, Wang Y, Yang K, Mitchell LA, Xue Y, Cai Y, Chen T, Dymond JS, Kang K, Gong J, Zeng X, Zhang Y, Li Y, Feng Q, et al. SCRaMbLE generates designed combinatorial stochastic diversity in synthetic chromosomes. Genome Research. PMID 26566658 DOI: 10.1101/Gr.193433.115  0.811
2015 Agmon N, Mitchell LA, Cai Y, Ikushima S, Chuang J, Zheng A, Choi WJ, Martin JA, Caravelli K, Stracquadanio G, Boeke JD. Yeast Golden Gate (yGG) for the Efficient Assembly of S. cerevisiae Transcription Units. Acs Synthetic Biology. 4: 853-9. PMID 25756291 DOI: 10.1021/Sb500372Z  0.577
2015 Cai Y, Agmon N, Choi WJ, Ubide A, Stracquadanio G, Caravelli K, Hao H, Bader JS, Boeke JD. Intrinsic biocontainment: multiplex genome safeguards combine transcriptional and recombinational control of essential yeast genes. Proceedings of the National Academy of Sciences of the United States of America. 112: 1803-8. PMID 25624482 DOI: 10.1073/Pnas.1424704112  0.658
2015 Lin Q, Jia B, Mitchell LA, Luo J, Yang K, Zeller KI, Zhang W, Xu Z, Stracquadanio G, Bader JS, Boeke JD, Yuan YJ. RADOM, an efficient in vivo method for assembling designed DNA fragments up to 10 kb long in Saccharomyces cerevisiae. Acs Synthetic Biology. 4: 213-20. PMID 24895839 DOI: 10.1021/Sb500241E  0.703
2014 Annaluru N, Muller H, Mitchell LA, Ramalingam S, Stracquadanio G, Richardson SM, Dymond JS, Kuang Z, Scheifele LZ, Cooper EM, Cai Y, Zeller K, Agmon N, Han JS, Hadjithomas M, et al. Total synthesis of a functional designer eukaryotic chromosome. Science (New York, N.Y.). 344: 55-8. PMID 24674868 DOI: 10.1126/Science.1249252  0.802
2014 Annaluru N, Muller H, Mitchell LA, Ramalingam S, Stracquadanio G, Richardson SM, Dymond JS, Kuang Z, Scheifele LZ, Cooper EM, Cai Y, Zeller K, Agmon N, Han JS, Hadjithomas M, et al. Total synthesis of a functional designer eukaryotic chromosome (Science (2014) 344, 6179 (55-58)) Science. 344. DOI: 10.1126/Science.1254596  0.77
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