Charles T. Lauhon - Publications

Affiliations: 
Pharmaceutical Sciences University of Wisconsin, Madison, Madison, WI 
Area:
Pharmacy, Organic Chemistry, Biochemistry

19 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Kopina BJ, Missoury S, Collinet B, Fulton MG, Cirio C, van Tilbeurgh H, Lauhon CT. Structure of a reaction intermediate mimic in t6A biosynthesis bound in the active site of the TsaBD heterodimer from Escherichia coli. Nucleic Acids Research. PMID 33524148 DOI: 10.1093/nar/gkab026  0.556
2019 Lauhon CT. Identification and characterization of genes required for 5-hydroxyuridine synthesis in and tRNA. Journal of Bacteriology. PMID 31358606 DOI: 10.1128/Jb.00433-19  0.356
2014 Neumann P, Lakomek K, Naumann PT, Erwin WM, Lauhon CT, Ficner R. Crystal structure of a 4-thiouridine synthetase-RNA complex reveals specificity of tRNA U8 modification. Nucleic Acids Research. 42: 6673-85. PMID 24705700 DOI: 10.1093/Nar/Gku249  0.698
2013 Naumann PT, Lauhon CT, Ficner R. Purification, crystallization and preliminary crystallographic analysis of a 4-thiouridine synthetase-RNA complex. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 69: 421-4. PMID 23545650 DOI: 10.1107/S1744309113004077  0.314
2012 Lauhon CT. Mechanism of N6-threonylcarbamoyladenonsine (t(6)A) biosynthesis: isolation and characterization of the intermediate threonylcarbamoyl-AMP. Biochemistry. 51: 8950-63. PMID 23072323 DOI: 10.1021/Bi301233D  0.443
2012 Kopina BJ, Lauhon CT. Efficient preparation of 2,4-diaminopyrimidine nucleosides: total synthesis of lysidine and agmatidine. Organic Letters. 14: 4118-21. PMID 22845013 DOI: 10.1021/Ol301769J  0.533
2010 Neumann P, Lakomek K, Naumann P, Dickmanns A, Lauhon CT, Ficner R. Crystal structure of a homodimeric 4-thiouridine synthetase-RNA complex Acta Crystallographica Section a Foundations of Crystallography. 66: s22-s22. DOI: 10.1107/S0108767310099514  0.358
2006 Lauhon CT. Orchestrating sulfur incorporation into RNA. Nature Chemical Biology. 2: 182-3. PMID 16547479 DOI: 10.1038/Nchembio0406-182  0.448
2004 Lauhon CT, Erwin WM, Ton GN. Substrate specificity for 4-thiouridine modification in Escherichia coli. The Journal of Biological Chemistry. 279: 23022-9. PMID 15037613 DOI: 10.1074/Jbc.M401757200  0.709
2004 Lauhon CT, Skovran E, Urbina HD, Downs DM, Vickery LE. Substitutions in an active site loop of Escherichia coli IscS result in specific defects in Fe-S cluster and thionucleoside biosynthesis in vivo. The Journal of Biological Chemistry. 279: 19551-8. PMID 14978044 DOI: 10.1074/Jbc.M401261200  0.367
2004 Wolfe MD, Ahmed F, Lacourciere GM, Lauhon CT, Stadtman TC, Larson TJ. Functional diversity of the rhodanese homology domain: The Escherichia coli ybbB gene encodes a selenophosphate-dependent tRNA 2-selenouridine synthase Journal of Biological Chemistry. 279: 1801-1809. PMID 14594807 DOI: 10.1074/Jbc.M310442200  0.355
2003 Kambampati R, Lauhon CT. MnmA and IscS are required for in vitro 2-thiouridine biosynthesis in Escherichia coli. Biochemistry. 42: 1109-17. PMID 12549933 DOI: 10.1021/Bi026536+  0.491
2002 Lauhon CT. Requirement for IscS in biosynthesis of all thionucleosides in Escherichia coli. Journal of Bacteriology. 184: 6820-9. PMID 12446632 DOI: 10.1128/Jb.184.24.6820-6829.2002  0.398
2000 Lauhon CT, Kambampati R. The iscS gene in Escherichia coli is required for the biosynthesis of 4- thiouridine, thiamin, and NAD Journal of Biological Chemistry. 275: 20096-20103. PMID 10781607 DOI: 10.1074/Jbc.M002680200  0.32
2000 Kambampati R, Lauhon CT. Evidence for the transfer of sulfane sulfur from IscS to ThiI during the in vitro biosynthesis of 4-thiouridine in Escherichia coli tRNA Journal of Biological Chemistry. 275: 10727-10730. PMID 10753862 DOI: 10.1074/Jbc.275.15.10727  0.514
1999 Kambampati R, Lauhon CT. IscS is a sulfurtransferase for the in vitro biosynthesis of 4- thiouridine in Escherichia coli tRNA Biochemistry. 38: 16561-16568. PMID 10600118 DOI: 10.1021/Bi991119R  0.447
1999 Zhang Y, Li D, Houtman JC, Witiak DT, Seltzer J, Bertics PJ, Lauhon CT. Design, combinatorial chemical synthesis and in vitro characterization of novel urea based gelatinase inhibitors Bioorganic and Medicinal Chemistry Letters. 9: 2823-2826. PMID 10522699 DOI: 10.1016/S0960-894X(99)00498-9  0.321
1995 Lauhon CT, Szostak JW. RNA aptamers that bind flavin and nicotinamide redox cofactors. Journal of the American Chemical Society. 117: 1246-57. PMID 11539282 DOI: 10.1021/Ja00109A008  0.3
1992 Alberg DG, Lauhon CT, Nyfeler R, Faessler A, Bartlett PA. Inhibition of 5-enolpyruvoylshikimate 3-phosphate (EPSP) synthase by analogs of the tetrahedral intermediate and of EPSP Journal of the American Chemical Society. 114: 3535-3546. DOI: 10.1021/Ja00035A058  0.324
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