Gregory W. Konat - Publications

School of Medicine West Virginia University, Morgantown, WV, United States 
Neuroscience Biology, Molecular Biology, Biochemistry

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Petrisko TJ, Konat GW. Peripheral viral challenge increases c-fos level in cerebral neurons. Metabolic Brain Disease. PMID 34406561 DOI: 10.1007/s11011-021-00819-z  1
2020 Petrisko TJ, Bloemer J, Pinky PD, Srinivas S, Heslin RT, Du Y, Setti SE, Hong H, Suppiramaniam V, Konat GW, Reed MN. Neuronal CXCL10/CXCR3 Axis Mediates the Induction of Cerebral Hyperexcitability by Peripheral Viral Challenge. Frontiers in Neuroscience. 14: 220. PMID 32265633 DOI: 10.3389/Fnins.2020.00220  1
2019 Petrisko TJ, Konat GW. Peripheral viral challenge exacerbates experimental autoimmune encephalomyelitis. Metabolic Brain Disease. PMID 30637619 DOI: 10.1007/S11011-019-0383-Y  1
2018 Bhardwaj R, Dod H, Sandhu MS, Bedi R, Dod S, Konat G, Chopra HK, Sharma R, Jain AC, Nanda N. Acute effects of diets rich in almonds and walnuts on endothelial function. Indian Heart Journal. 70: 497-501. PMID 30170643 DOI: 10.1016/J.Ihj.2018.01.030  1
2017 Hunsberger HC, Konat GW, Reed MN. Peripheral viral challenge elevates extracellular glutamate in the hippocampus leading to seizure hypersusceptibility. Journal of Neurochemistry. PMID 28244106 DOI: 10.1111/Jnc.13999  1
2016 Hunsberger HC, Wang D, Petrisko TJ, Alhowail A, Setti SE, Suppiramaniam V, Konat GW, Reed MN. Peripherally restricted viral challenge elevates extracellular glutamate and enhances synaptic transmission in the hippocampus. Journal of Neurochemistry. PMID 27168075 DOI: 10.1111/Jnc.13665  1
2015 Michalovicz LT, Lally B, Konat GW. Peripheral challenge with a viral mimic upregulates expression of the complement genes in the hippocampus. Journal of Neuroimmunology. 285: 137-42. PMID 26198930 DOI: 10.1016/J.Jneuroim.2015.06.003  1
2014 Michalovicz LT, Konat GW. Peripherally restricted acute phase response to a viral mimic alters hippocampal gene expression. Metabolic Brain Disease. 29: 75-86. PMID 24363211 DOI: 10.1007/S11011-013-9471-6  1
2013 Borysiewicz E, Doppalapudi S, Kirschman LT, Konat GW. TLR3 ligation protects human astrocytes against oxidative stress Journal of Neuroimmunology. 255: 54-59. PMID 23245579 DOI: 10.1016/J.Jneuroim.2012.11.002  1
2011 Konat GW, Lally BE, Toth AA, Salm AK. Peripheral immune challenge with viral mimic during early postnatal period robustly enhances anxiety-like behavior in young adult rats. Metabolic Brain Disease. 26: 237-40. PMID 21643765 DOI: 10.1007/S11011-011-9244-Z  1
2011 Kirschman LT, Borysiewicz E, Fil D, Konat GW. Peripheral immune challenge with dsRNA enhances kainic acid-induced status epilepticus. Metabolic Brain Disease. 26: 91-3. PMID 21305346 DOI: 10.1007/S11011-011-9236-Z  1
2011 Fil D, Borysiewicz E, Konat GW. A broad upregulation of cerebral chemokine genes by peripherally-generated inflammatory mediators. Metabolic Brain Disease. 26: 49-59. PMID 21258854 DOI: 10.1007/S11011-010-9231-9  1
2011 Callery PS, Wichitnithad W, Borysiewicz E, Konat GW. Abstract 3255: Tetrahydropyridine derivatives: Novel and potent histone demethylase LSD1 inhibitors Cancer Research. 71: 3255-3255. DOI: 10.1158/1538-7445.Am2011-3255  1
2010 Darwish DS, Wang D, Konat GW, Schreurs BG. Dietary cholesterol impairs memory and memory increases brain cholesterol and sulfatide levels. Behavioral Neuroscience. 124: 115-23. PMID 20141286 DOI: 10.1037/A0018253  1
2010 Dod HS, Bhardwaj R, Sajja V, Weidner G, Hobbs GR, Konat GW, Manivannan S, Gharib W, Warden BE, Nanda NC, Beto RJ, Ornish D, Jain AC. Effect of intensive lifestyle changes on endothelial function and on inflammatory markers of atherosclerosis. The American Journal of Cardiology. 105: 362-7. PMID 20102949 DOI: 10.1016/J.Amjcard.2009.09.038  1
2009 Borysiewicz E, Fil D, Dlaboga D, O'Donnell JM, Konat GW. Phosphodiesterase 4B2 gene is an effector of Toll-like receptor signaling in astrocytes. Metabolic Brain Disease. 24: 481-91. PMID 19728060 DOI: 10.1007/S11011-009-9150-9  1
2009 Konat GW, Borysiewicz E, Fil D, James I. Peripheral challenge with double-stranded RNA elicits global up-regulation of cytokine gene expression in the brain. Journal of Neuroscience Research. 87: 1381-8. PMID 19115408 DOI: 10.1002/Jnr.21958  1
2009 Borysiewicz E, Fil D, Konat GW. Rho proteins are negative regulators of TLR2, TLR3, and TLR4 signaling in astrocytes. Journal of Neuroscience Research. 87: 1565-72. PMID 19115402 DOI: 10.1002/Jnr.21968  1
2009 Shrader CD, Bailey KM, Konat GW, Cilento EV, Reilly FD. Insulin enhances proliferation and viability of human umbilical vein endothelial cells. Archives of Dermatological Research. 301: 159-66. PMID 19115062 DOI: 10.1007/S00403-008-0921-7  1
2008 Younis IR, Elliott M, Peer CJ, Cooper AJ, Pinto JT, Konat GW, Kraszpulski M, Petros WP, Callery PS. Dehydroalanine analog of glutathione: an electrophilic busulfan metabolite that binds to human glutathione S-transferase A1-1. The Journal of Pharmacology and Experimental Therapeutics. 327: 770-6. PMID 18791061 DOI: 10.1124/Jpet.108.142208  1
2008 Konat GW, Kraszpulski M, James I, Zhang HT, Abraham J. Cognitive dysfunction induced by chronic administration of common cancer chemotherapeutics in rats. Metabolic Brain Disease. 23: 325-33. PMID 18690526 DOI: 10.1007/S11011-008-9100-Y  1
2008 Konat GW, Krasowska-Zoladek A, Kraszpulski M. Statins enhance toll-like receptor 4-mediated cytokine gene expression in astrocytes: implication of Rho proteins in negative feedback regulation. Journal of Neuroscience Research. 86: 603-9. PMID 17896797 DOI: 10.1002/Jnr.21509  1
2007 Wiltshire T, Senft J, Wang Y, Konat GW, Wenger SL, Reed E, Wang W. BRCA1 contributes to cell cycle arrest and chemoresistance in response to the anticancer agent irofulven. Molecular Pharmacology. 71: 1051-60. PMID 17229870 DOI: 10.1124/Mol.106.029504  1
2007 Krasowska-Zoladek A, Banaszewska M, Kraszpulski M, Konat GW. Kinetics of inflammatory response of astrocytes induced by TLR 3 and TLR4 ligation. Journal of Neuroscience Research. 85: 205-12. PMID 17061254 DOI: 10.1002/Jnr.21088  1
2006 Konat GW, Kielian T, Marriott I. The role of Toll-like receptors in CNS response to microbial challenge. Journal of Neurochemistry. 99: 1-12. PMID 16899072 DOI: 10.1111/J.1471-4159.2006.04076.X  1
2006 Banaszewska M, Konat GW. Nucleotides induce higher order chromatin degradation. Molecular and Cellular Biochemistry. 282: 39-43. PMID 16317510 DOI: 10.1007/S11010-006-1154-8  1
2006 Sanga M, Younis IR, Tirumalai PS, Bland TM, Banaszewska M, Konat GW, Tracy TS, Gannett PM, Callery PS. Epoxidation of the methamphetamine pyrolysis product, trans-phenylpropene, to trans-phenylpropylene oxide by CYP enzymes and stereoselective glutathione adduct formation. Toxicology and Applied Pharmacology. 211: 148-56. PMID 16038959 DOI: 10.1016/J.Taap.2005.06.017  1
2004 Krasowska A, Konat GW. Vulnerability of brain tissue to inflammatory oxidant, hypochlorous acid. Brain Research. 997: 176-84. PMID 14706870 DOI: 10.1016/J.Brainres.2003.09.080  1
2003 Konat GW. H2O2-induced higher order chromatin degradation: a novel mechanism of oxidative genotoxicity. Journal of Biosciences. 28: 57-60. PMID 12682425 DOI: 10.1007/Bf02970132  1
2003 Konat GW, Kofke WA, Miric S. Toxicity of compound A to C6 rat glioma cells. Metabolic Brain Disease. 18: 11-5. PMID 12603078 DOI: 10.1023/A:1021922500998  1
2003 Bai H, Konat GW. Hydrogen peroxide mediates higher order chromatin degradation Neurochemistry International. 42: 123-129. PMID 12421592 DOI: 10.1016/S0197-0186(02)00072-4  1
2002 Konat GW. Higher order chromatin degradation: implications for neurodegeneration. Neurochemical Research. 27: 1447-51. PMID 12512948 DOI: 10.1023/A:1021688119574  1
2001 LoPresti P, Konat GW. Hydrogen peroxide induces transient dephosphorylation of tau protein in cultured rat oligodendrocytes Neuroscience Letters. 311: 142-144. PMID 11567798 DOI: 10.1016/S0304-3940(01)02137-1  1
2001 Konat GW, Mouzannar R, Bai H. Higher order chromatin degradation in glial cells: the role of calcium. Neurochemistry International. 39: 179-86. PMID 11434975 DOI: 10.1016/S0197-0186(01)00030-4  1
2001 Mouzannar R, Miric SJ, Wiggins RC, Konat GW. Hydrogen peroxide induces rapid digestion of oligodendrocyte chromatin into high molecular weight fragments. Neurochemistry International. 38: 9-15. PMID 10913683 DOI: 10.1016/S0197-0186(00)00066-8  1
1999 Laszkiewicz I, Wiggins RC, Konat GW. Antisense oligodeoxynucleotides targeted to MAG mRNA profoundly alter BP and PLP mRNA expression in differentiating oligodendrocytes: A caution Metabolic Brain Disease. 14: 197-203. PMID 10646695  1
1999 Royland JE, Konat GW, Wiggins RC. Differentiation dependent activation of the myelin genes in purified oligodendrocytes is highly resistant to hypoglycemia Metabolic Brain Disease. 14: 189-195. PMID 10646694 DOI: 10.1023/A:1020614809546  1
1999 Laszkiewicz I, Mouzannar R, Wiggins RC, Konat GW. Delayed oligodendrocyte degeneration induced by brief exposure to hydrogen peroxide. Journal of Neuroscience Research. 55: 303-10. PMID 10348661 DOI: 10.1002/(Sici)1097-4547(19990201)55:3<303::Aid-Jnr5>3.0.Co;2-C  1
1997 Laszkiewicz I, Grubinska B, Wiggins RC, Konat GW. Structural characterization of myelin-associated glycoprotein gene core promoter Journal of Neuroscience Research. 50: 928-936. PMID 9452007 DOI: 10.1002/(SICI)1097-4547(19971215)50:6<928::AID-JNR3>3.0.CO;2-F  1
1997 Gu J, Royland JE, Wiggins RC, Konat GW. Selenium is required for normal upregulation of myelin genes in differentiating oligodendrocytes Journal of Neuroscience Research. 47: 626-635. PMID 9089211 DOI: 10.1002/(Sici)1097-4547(19970315)47:6<626::Aid-Jnr8>3.0.Co;2-F  1
1996 Konat GW. Generation of high efficiency ssDNA hybridization probes by linear polymerase chain reaction (LPCR) Scanning Microscopy. Supplement. 10: 57-60. PMID 9601529  1
1996 Konat GW. Chromatin structure and transcriptional activity of MAG gene Acta Neurobiologiae Experimentalis. 56: 281-285. PMID 8787187  1
1994 Yassini PR, Stickler DL, Bloomfield SM, Wiggins RC, Konat GW. Glioma-stimulated chemoattraction of endothelial cells and fibroblasts in vitro: a model for the study of glioma-induced angiogenesis Metabolic Brain Disease. 9: 391-399. PMID 7534866 DOI: 10.1007/Bf02098885  1
1994 Grubinska B, Laszkiewicz I, Royland J, Wiggins RC, Konat GW. Differentiation-specific demethylation of myelin associated glycoprotein gene in cultured oligodendrocytes Journal of Neuroscience Research. 39: 233-242. PMID 7532722 DOI: 10.1002/jnr.490390302  1
1994 Ye P, Laszkiewicz I, Wiggins RC, Konat GW. Transcriptional regulation of myelin associated glycoprotein gene expression by cyclic AMP Journal of Neuroscience Research. 37: 683-690. PMID 7519273 DOI: 10.1002/jnr.490370603  1
1994 Zhu W, Wiggins RC, Konat GW. Glucocorticoid‐induced upregulation of proteolipid protein and myelin‐associated glycoprotein genes in C6 cells Journal of Neuroscience Research. 37: 208-212. PMID 7512149 DOI: 10.1002/Jnr.490370206  1
1993 Gu J, Yassini P, Goldberg G, Zhu W, Konat GW, Wiggins RC. Cocaine cytotoxicity in serum-free environment: C6 glioma cell culture Neurotoxicology. 14: 19-22. PMID 8361674  1
1993 Yassini PR, Wiggins RC, Konat GW. Spatiotemporal expression of SCIP and myelin genes in rat brain during early postnatal development Developmental Neuroscience. 15: 128-132. PMID 7513278 DOI: 10.1159/000111325  1
1993 Royland JE, Konat GW, Wiggins RC. Myelin gene activation: A glucose sensitive critical period in development Journal of Neuroscience Research. 36: 399-404. PMID 7505839 DOI: 10.1002/Jnr.490360406  1
1992 Royland J, Konat GW, Kanoh M, Wiggins RC. Down regulation of myelin-specific mRNAs in the mechanism of hypomyelination in the undernourisched developing brain Developmental Brain Research. 65: 223-226. PMID 1373995 DOI: 10.1016/0165-3806(92)90183-W  1
1992 Banik NL, Chakrabarti AK, Konat GW, Gantt-Wilford G, Hogan EL. Calcium-activated neutral proteinase (calpain) activity in C6 cell line: compartmentation of mu and m calpain. Journal of Neuroscience Research. 31: 708-14. PMID 1315874 DOI: 10.1002/Jnr.490310414  1
1992 Royland J, Klinkhachorn P, Konat G, Wiggins RC. How much undernourishment is required to retard brain myelin development. Neurochemistry International. 21: 269-74. PMID 1303155 DOI: 10.1016/0197-0186(92)90157-M  1
1992 Royland JE, Wiggins RC, Konat GW. Myelin isolation: Comparison of sedimentation and flotation techniques Neurochemistry International. 21: 171-175. PMID 1303149 DOI: 10.1016/0197-0186(92)90143-F  1
1992 Kanoh M, Wiggins RC, Konat G. Differential upregulation of PLP and MAG genes in C6 glioma cells by N2A neuroblastoma conditioned medium. Metabolic Brain Disease. 7: 147-156. PMID 1279370 DOI: 10.1007/Bf01000160  1
1991 Bednarczuk TA, Wiggins RC, Konat GW. Generation of high efficiency, single-stranded DNA hybridization probes by PCR Biotechniques. 10: 478. PMID 1867856  1
1991 Kanoh M, Ye P, Zhu W, Wiggins RC, Konat G. Effect of culture conditions on PLP and MAG gene expression in rat glioma C6 cells. Metabolic Brain Disease. 6: 133-143. PMID 1723486 DOI: 10.1007/Bf00996905  1
1985 Konat GW, Wiggins RC. Effect of Reactive Oxygen Species on Myelin Membrane Proteins Journal of Neurochemistry. 45: 1113-1118. PMID 4031880 DOI: 10.1111/j.1471-4159.1985.tb05530.x  1
1982 Konat G, Offner H, Lev-Ram V, Cohen O, Schwartz M, Cohen IR, Sela BA. Abnofmalities in brain myelin or rabbits with experimental autoimmune multiple sclerosis-like disease induced by immunization to gangliosides. Acta Neurologica Scandinavica. 66: 568-74. PMID 7148399 DOI: 10.1111/J.1600-0404.1982.Tb03144.X  1
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