Stephen E. Girardin - Publications

Affiliations: 
Laboratory Medicine and Pathobiology University of Toronto, Toronto, ON, Canada 
Area:
Cell Biology, Immunology, Biochemistry

145 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Abdel-Nour M, Carneiro LAM, Downey J, Tsalikis J, Outlioua A, Prescott D, Da Costa LS, Hovingh ES, Farahvash A, Gaudet RG, Molinaro R, van Dalen R, Lau CCY, Azimi FC, Escalante NK, ... ... Girardin SE, et al. The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling. Science (New York, N.Y.). 365. PMID 31273097 DOI: 10.1126/science.aaw4144  0.64
2019 Winsor N, Krustev C, Bruce J, Philpott DJ, Girardin SE. Canonical and non-canonical inflammasomes in intestinal epithelial cells. Cellular Microbiology. e13079. PMID 31265745 DOI: 10.1111/cmi.13079  0.64
2019 Robertson SJ, Lemire P, Maughan H, Goethel A, Turpin W, Bedrani L, Guttman DS, Croitoru K, Girardin SE, Philpott DJ. Comparison of Co-housing and Littermate Methods for Microbiota Standardization in Mouse Models. Cell Reports. 27: 1910-1919.e2. PMID 31067473 DOI: 10.1016/j.celrep.2019.04.023  0.64
2019 Molinaro R, Mukherjee T, Flick R, Philpott DJ, Girardin SE. Trace levels of peptidoglycan in serum underlie the NOD-dependent cytokine response to endoplasmic reticulum stress. The Journal of Biological Chemistry. PMID 30996003 DOI: 10.1074/jbc.RA119.007997  0.64
2019 Tsalikis J, Abdel-Nour M, Farahvash A, Sorbara MT, Poon S, Philpott DJ, Girardin SE. Isoginkgetin, a natural biflavonoid proteasome inhibitor, sensitizes cancer cells to apoptosis via disruption of lysosomal homeostasis and impaired protein clearance. Molecular and Cellular Biology. PMID 30910794 DOI: 10.1128/MCB.00489-18  0.64
2019 Sun T, Ferrero RL, Girardin SE, Gommerman JL, Philpott DJ. NLRC5 deficiency has a moderate impact on immunodominant CD8 T cell responses during rotavirus infection of adult mice. Immunology and Cell Biology. PMID 30768806 DOI: 10.1111/imcb.12244  0.64
2018 Mukherjee T, Hovingh ES, Foerster EG, Abdel-Nour M, Philpott DJ, Girardin SE. NOD1 and NOD2 in inflammation, immunity and disease. Archives of Biochemistry and Biophysics. PMID 30578751 DOI: 10.1016/j.abb.2018.12.022  0.64
2018 Platnich JM, Chung H, Lau A, Sandall CF, Bondzi-Simpson A, Chen HM, Komada T, Trotman-Grant AC, Brandelli JR, Chun J, Beck PL, Philpott DJ, Girardin SE, Ho M, Johnson RP, et al. Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome. Cell Reports. 25: 1525-1536.e7. PMID 30404007 DOI: 10.1016/j.celrep.2018.09.071  0.64
2018 Robertson SJ, Goethel A, Girardin SE, Philpott DJ. Innate Immune Influences on the Gut Microbiome: Lessons from Mouse Models. Trends in Immunology. PMID 30377046 DOI: 10.1016/j.it.2018.10.004  0.64
2018 Killackey SA, Rahman MA, Soares F, Zhang AB, Abdel-Nour M, Philpott DJ, Girardin SE. The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1. Molecular and Cellular Biochemistry. PMID 30191480 DOI: 10.1007/s11010-018-3444-3  0.64
2018 Sorbara MT, Foerster EG, Tsalikis J, Abdel-Nour M, Mangiapane J, Sirluck-Schroeder I, Tattoli I, van Dalen R, Isenman DE, Rohde JR, Girardin SE, Philpott DJ. Complement C3 Drives Autophagy-Dependent Restriction of Cyto-invasive Bacteria. Cell Host & Microbe. 23: 644-652.e5. PMID 29746835 DOI: 10.1016/j.chom.2018.04.008  0.64
2018 Costford SR, Tattoli I, Duan FT, Volchuk A, Klip A, Philpott DJ, Woo M, Girardin SE. Male Mice Lacking NLRX1 Are Partially Protected From High-Fat Diet-Induced Hyperglycemia. Journal of the Endocrine Society. 2: 336-347. PMID 29577109 DOI: 10.1210/js.2017-00360  0.64
2018 Lopes F, Keita ÅV, Saxena A, Reyes JL, Mancini N, Rajabi AA, Wang A, Baggio C, Dicay M, van Dalen R, Ahn Y, Carneiro M, Peters N, Rho JM, MacNaughton W, ... Girardin SE, et al. ER-stress mobilization of death-associated protein kinase-1-dependent xenophagy counteracts mitochondria stress-induced epithelial barrier dysfunction. The Journal of Biological Chemistry. PMID 29317503 DOI: 10.1074/jbc.RA117.000809  0.64
2017 Lemire P, Robertson SJ, Maughan H, Tattoli I, Streutker CJ, Platnich JM, Muruve DA, Philpott DJ, Girardin SE. The NLR Protein NLRP6 Does Not Impact Gut Microbiota Composition. Cell Reports. 21: 3653-3661. PMID 29281815 DOI: 10.1016/j.celrep.2017.12.026  0.64
2017 Chan KL, Tam TH, Boroumand P, Prescott D, Costford SR, Escalante NK, Fine N, Tu Y, Robertson SJ, Prabaharan D, Liu Z, Bilan PJ, Salter MW, Glogauer M, Girardin SE, et al. Circulating NOD1 Activators and Hematopoietic NOD1 Contribute to Metabolic Inflammation and Insulin Resistance. Cell Reports. 18: 2415-2426. PMID 28273456 DOI: 10.1016/j.celrep.2017.02.027  0.64
2016 Escalante NK, Lemire P, Cruz Tleugabulova M, Prescott D, Mortha A, Streutker CJ, Girardin SE, Philpott DJ, Mallevaey T. The common mouse protozoa Tritrichomonas muris alters mucosal T cell homeostasis and colitis susceptibility. The Journal of Experimental Medicine. PMID 27836928 DOI: 10.1084/jem.20161776  0.64
2016 Tsalikis J, Pan Q, Tattoli I, Maisonneuve C, Blencowe BJ, Philpott DJ, Girardin SE. The transcriptional and splicing landscape of intestinal organoids undergoing nutrient starvation or endoplasmic reticulum stress. Bmc Genomics. 17: 680. PMID 27561422 DOI: 10.1186/s12864-016-2999-1  0.64
2016 Tattoli I, Killackey SA, Foerster EG, Molinaro R, Maisonneuve C, Rahman MA, Winer S, Winer DA, Streutker CJ, Philpott DJ, Girardin SE. NLRX1 Acts as an Epithelial-Intrinsic Tumor Suppressor through the Modulation of TNF-Mediated Proliferation. Cell Reports. PMID 26971996 DOI: 10.1016/j.celrep.2016.02.065  0.64
2015 Philipson CW, Bassaganya-Riera J, Viladomiu M, Kronsteiner B, Abedi V, Hoops S, Michalak P, Kang L, Girardin SE, Hontecillas R. Modeling the Regulatory Mechanisms by Which NLRX1 Modulates Innate Immune Responses to Helicobacter pylori Infection. Plos One. 10: e0137839. PMID 26367386 DOI: 10.1371/journal.pone.0137839  0.64
2015 Tsalikis J, Tattoli I, Ling A, Sorbara MT, Croitoru DO, Philpott DJ, Girardin SE. Intracellular Bacterial Pathogens Trigger the Formation of U Small Nuclear RNA Bodies (U Bodies) through Metabolic Stress Induction. The Journal of Biological Chemistry. 290: 20904-18. PMID 26134566 DOI: 10.1074/jbc.M115.659466  0.64
2015 Luck H, Tsai S, Chung J, Clemente-Casares X, Ghazarian M, Revelo XS, Lei H, Luk CT, Shi SY, Surendra A, Copeland JK, Ahn J, Prescott D, Rasmussen BA, Chng MH, ... ... Girardin SE, et al. Regulation of obesity-related insulin resistance with gut anti-inflammatory agents. Cell Metabolism. 21: 527-42. PMID 25863246 DOI: 10.1016/j.cmet.2015.03.001  0.64
2015 Powell JJ, Thomas-McKay E, Thoree V, Robertson J, Hewitt RE, Skepper JN, Brown A, Hernandez-Garrido JC, Midgley PA, Gomez-Morilla I, Grime GW, Kirkby KJ, Mabbott NA, Donaldson DS, Williams IR, ... ... Girardin SE, et al. An endogenous nanomineral chaperones luminal antigen and peptidoglycan to intestinal immune cells. Nature Nanotechnology. 10: 361-9. PMID 25751305 DOI: 10.1038/nnano.2015.19  0.64
2015 Sorbara MT, Girardin SE. Emerging themes in bacterial autophagy. Current Opinion in Microbiology. 23: 163-70. PMID 25497773 DOI: 10.1016/j.mib.2014.11.020  0.64
2014 Tattoli I, Sorbara MT, Philpott DJ, Girardin SE. Stalling autophagy: a new function for Listeria phospholipases. Microbial Cell (Graz, Austria). 1: 48-50. PMID 28357210 DOI: 10.15698/mic2014.01.124  0.64
2014 Belcheva A, Irrazabal T, Robertson SJ, Streutker C, Maughan H, Rubino S, Moriyama EH, Copeland JK, Kumar S, Green B, Geddes K, Pezo RC, Navarre WW, Milosevic M, Wilson BC, ... Girardin SE, et al. Gut microbial metabolism drives transformation of MSH2-deficient colon epithelial cells. Cell. 158: 288-99. PMID 25036629 DOI: 10.1016/j.cell.2014.04.051  0.64
2014 Dooley HC, Razi M, Polson HE, Girardin SE, Wilson MI, Tooze SA. WIPI2 links LC3 conjugation with PI3P, autophagosome formation, and pathogen clearance by recruiting Atg12-5-16L1. Molecular Cell. 55: 238-52. PMID 24954904 DOI: 10.1016/j.molcel.2014.05.021  0.64
2014 Soares F, Tattoli I, Rahman MA, Robertson SJ, Belcheva A, Liu D, Streutker C, Winer S, Winer DA, Martin A, Philpott DJ, Arnoult D, Girardin SE. The mitochondrial protein NLRX1 controls the balance between extrinsic and intrinsic apoptosis. The Journal of Biological Chemistry. 289: 19317-30. PMID 24867956 DOI: 10.1074/jbc.M114.550111  0.64
2014 Jaworska J, Coulombe F, Downey J, Tzelepis F, Shalaby K, Tattoli I, Berube J, Rousseau S, Martin JG, Girardin SE, McCullers JA, Divangahi M. NLRX1 prevents mitochondrial induced apoptosis and enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein. Proceedings of the National Academy of Sciences of the United States of America. 111: E2110-9. PMID 24799673 DOI: 10.1073/pnas.1322118111  0.64
2014 Irrazábal T, Belcheva A, Girardin SE, Martin A, Philpott DJ. The multifaceted role of the intestinal microbiota in colon cancer. Molecular Cell. 54: 309-20. PMID 24766895 DOI: 10.1016/j.molcel.2014.03.039  0.64
2014 Abdel-Nour M, Tsalikis J, Kleinman D, Girardin SE. The emerging role of mTOR signalling in antibacterial immunity. Immunology and Cell Biology. 92: 346-53. PMID 24518980 DOI: 10.1038/icb.2014.3  0.64
2014 Frirdich E, Vermeulen J, Biboy J, Soares F, Taveirne ME, Johnson JG, DiRita VJ, Girardin SE, Vollmer W, Gaynor EC. Peptidoglycan LD-carboxypeptidase Pgp2 influences Campylobacter jejuni helical cell shape and pathogenic properties and provides the substrate for the DL-carboxypeptidase Pgp1. The Journal of Biological Chemistry. 289: 8007-18. PMID 24394413 DOI: 10.1074/jbc.M113.491829  0.64
2014 Philpott DJ, Sorbara MT, Robertson SJ, Croitoru K, Girardin SE. NOD proteins: regulators of inflammation in health and disease. Nature Reviews. Immunology. 14: 9-23. PMID 24336102 DOI: 10.1038/nri3565  0.64
2014 Sorbara MT, Ellison LK, Ramjeet M, Travassos LH, Jones NL, Girardin SE, Philpott DJ. The Protein ATG16L1 Suppresses Inflammatory Cytokines Induced by the Intracellular Sensors Nod1 and Nod2 in an Autophagy-Independent Manner Immunity. 40: 303. DOI: 10.1016/j.immuni.2014.01.001  0.64
2013 Sorbara MT, Ellison LK, Ramjeet M, Travassos LH, Jones NL, Girardin SE, Philpott DJ. The protein ATG16L1 suppresses inflammatory cytokines induced by the intracellular sensors Nod1 and Nod2 in an autophagy-independent manner. Immunity. 39: 858-73. PMID 24238340 DOI: 10.1016/j.immuni.2013.10.013  0.64
2013 Selvanantham T, Escalante NK, Cruz Tleugabulova M, Fiévé S, Girardin SE, Philpott DJ, Mallevaey T. Nod1 and Nod2 enhance TLR-mediated invariant NKT cell activation during bacterial infection. Journal of Immunology (Baltimore, Md. : 1950). 191: 5646-54. PMID 24163408 DOI: 10.4049/jimmunol.1301412  0.64
2013 Tattoli I, Sorbara MT, Yang C, Tooze SA, Philpott DJ, Girardin SE. Listeria phospholipases subvert host autophagic defenses by stalling pre-autophagosomal structures. The Embo Journal. 32: 3066-78. PMID 24162724 DOI: 10.1038/emboj.2013.234  0.64
2013 Abdul-Sater AA, Tattoli I, Jin L, Grajkowski A, Levi A, Koller BH, Allen IC, Beaucage SL, Fitzgerald KA, Ting JP, Cambier JC, Girardin SE, Schindler C. Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome. Embo Reports. 14: 900-6. PMID 24008845 DOI: 10.1038/embor.2013.132  0.64
2013 Rubino SJ, Geddes K, Magalhaes JG, Streutker C, Philpott DJ, Girardin SE. Constitutive induction of intestinal Tc17 cells in the absence of hematopoietic cell-specific MHC class II expression. European Journal of Immunology. 43: 2896-906. PMID 23881368 DOI: 10.1002/eji.201243028  0.64
2013 Tsalikis J, Croitoru DO, Philpott DJ, Girardin SE. Nutrient sensing and metabolic stress pathways in innate immunity. Cellular Microbiology. 15: 1632-41. PMID 23834352 DOI: 10.1111/cmi.12165  0.64
2013 Zarantonelli ML, Skoczynska A, Antignac A, El Ghachi M, Deghmane AE, Szatanik M, Mulet C, Werts C, Peduto L, d'Andon MF, Thouron F, Nato F, Lebourhis L, Philpott DJ, Girardin SE, et al. Penicillin resistance compromises Nod1-dependent proinflammatory activity and virulence fitness of neisseria meningitidis. Cell Host & Microbe. 13: 735-45. PMID 23768497 DOI: 10.1016/j.chom.2013.04.016  0.64
2013 Lemaitre B, Girardin SE. Translation inhibition and metabolic stress pathways in the host response to bacterial pathogens. Nature Reviews. Microbiology. 11: 365-9. PMID 23669888 DOI: 10.1038/nrmicro3029  0.64
2013 Robertson SJ, Zhou JY, Geddes K, Rubino SJ, Cho JH, Girardin SE, Philpott DJ. Nod1 and Nod2 signaling does not alter the composition of intestinal bacterial communities at homeostasis. Gut Microbes. 4: 222-31. PMID 23549220 DOI: 10.4161/gmic.24373  0.64
2013 Lin GH, Wortzman ME, Girardin SE, Philpott DJ, Watts TH. T cell intrinsic NOD2 is dispensable for CD8 T cell immunity. Plos One. 8: e56014. PMID 23405246 DOI: 10.1371/journal.pone.0056014  0.64
2013 Tourneur E, Ben Mkaddem S, Chassin C, Bens M, Goujon JM, Charles N, Pellefigues C, Aloulou M, Hertig A, Monteiro RC, Girardin SE, Philpott DJ, Rondeau E, Elbim C, Werts C, et al. Cyclosporine A impairs nucleotide binding oligomerization domain (Nod1)-mediated innate antibacterial renal defenses in mice and human transplant recipients. Plos Pathogens. 9: e1003152. PMID 23382681 DOI: 10.1371/journal.ppat.1003152  0.64
2013 Rubino SJ, Magalhaes JG, Philpott D, Bahr GM, Blanot D, Girardin SE. Identification of a synthetic muramyl peptide derivative with enhanced Nod2 stimulatory capacity. Innate Immunity. 19: 493-503. PMID 23339926 DOI: 10.1177/1753425912471691  0.64
2013 Soares F, Tattoli I, Wortzman ME, Arnoult D, Philpott DJ, Girardin SE. NLRX1 does not inhibit MAVS-dependent antiviral signalling. Innate Immunity. 19: 438-48. PMID 23212541 DOI: 10.1177/1753425912467383  0.64
2013 Robertson SJ, Girardin SE. Nod-like receptors in intestinal host defense: controlling pathogens, the microbiota, or both? Current Opinion in Gastroenterology. 29: 15-22. PMID 23132210 DOI: 10.1097/MOG.0b013e32835a68ea  0.64
2012 Stroo I, Butter LM, Claessen N, Teske GJ, Rubino SJ, Girardin SE, Florquin S, Leemans JC. Phenotyping of Nod1/2 double deficient mice and characterization of Nod1/2 in systemic inflammation and associated renal disease. Biology Open. 1: 1239-47. PMID 23259058 DOI: 10.1242/bio.2012554  0.48
2012 Tattoli I, Philpott DJ, Girardin SE. The bacterial and cellular determinants controlling the recruitment of mTOR to the Salmonella-containing vacuole. Biology Open. 1: 1215-25. PMID 23259056 DOI: 10.1242/bio.20122840  0.64
2012 Tattoli I, Sorbara MT, Philpott DJ, Girardin SE. Bacterial autophagy: the trigger, the target and the timing. Autophagy. 8: 1848-50. PMID 22932645 DOI: 10.4161/auto.21863  0.64
2012 Ling A, Soares F, Croitoru DO, Tattoli I, Carneiro LA, Boniotto M, Benko S, Philpott DJ, Girardin SE. Post-transcriptional inhibition of luciferase reporter assays by the Nod-like receptor proteins NLRX1 and NLRC3. The Journal of Biological Chemistry. 287: 28705-16. PMID 22718770 DOI: 10.1074/jbc.M111.333146  0.64
2012 Tattoli I, Sorbara MT, Vuckovic D, Ling A, Soares F, Carneiro LA, Yang C, Emili A, Philpott DJ, Girardin SE. Amino acid starvation induced by invasive bacterial pathogens triggers an innate host defense program. Cell Host & Microbe. 11: 563-75. PMID 22704617 DOI: 10.1016/j.chom.2012.04.012  0.64
2012 Rubino SJ, Selvanantham T, Girardin SE, Philpott DJ. Nod-like receptors in the control of intestinal inflammation. Current Opinion in Immunology. 24: 398-404. PMID 22677577 DOI: 10.1016/j.coi.2012.04.010  0.64
2012 Lee J, Geddes K, Streutker C, Philpott DJ, Girardin SE. Role of mouse peptidoglycan recognition protein PGLYRP2 in the innate immune response to Salmonella enterica serovar Typhimurium infection in vivo. Infection and Immunity. 80: 2645-54. PMID 22615249 DOI: 10.1128/IAI.00168-12  0.64
2012 Frirdich E, Biboy J, Adams C, Lee J, Ellermeier J, Gielda LD, Dirita VJ, Girardin SE, Vollmer W, Gaynor EC. Peptidoglycan-modifying enzyme Pgp1 is required for helical cell shape and pathogenicity traits in Campylobacter jejuni. Plos Pathogens. 8: e1002602. PMID 22457624 DOI: 10.1371/journal.ppat.1002602  0.64
2012 Rubino SJ, Geddes K, Girardin SE. Innate IL-17 and IL-22 responses to enteric bacterial pathogens. Trends in Immunology. 33: 112-8. PMID 22342740 DOI: 10.1016/j.it.2012.01.003  0.64
2012 Raju D, Hussey S, Ang M, Terebiznik MR, Sibony M, Galindo-Mata E, Gupta V, Blanke SR, Delgado A, Romero-Gallo J, Ramjeet MS, Mascarenhas H, Peek RM, Correa P, Streutker C, ... ... Girardin SE, et al. Vacuolating cytotoxin and variants in Atg16L1 that disrupt autophagy promote Helicobacter pylori infection in humans. Gastroenterology. 142: 1160-71. PMID 22333951 DOI: 10.1053/j.gastro.2012.01.043  0.64
2012 Lacroix-Lamandé S, d'Andon MF, Michel E, Ratet G, Philpott DJ, Girardin SE, Boneca IG, Vandewalle A, Werts C. Downregulation of the Na/K-ATPase pump by leptospiral glycolipoprotein activates the NLRP3 inflammasome. Journal of Immunology (Baltimore, Md. : 1950). 188: 2805-14. PMID 22323544 DOI: 10.4049/jimmunol.1101987  0.64
2012 Fritz JH, Rojas OL, Simard N, McCarthy DD, Hapfelmeier S, Rubino S, Robertson SJ, Larijani M, Gosselin J, Ivanov II, Martin A, Casellas R, Philpott DJ, Girardin SE, McCoy KD, et al. Acquisition of a multifunctional IgA+ plasma cell phenotype in the gut. Nature. 481: 199-203. PMID 22158124 DOI: 10.1038/nature10698  0.64
2012 Blanot D, Lee J, Girardin SE. Synthesis and biological evaluation of biotinyl hydrazone derivatives of muramyl peptides. Chemical Biology & Drug Design. 79: 2-8. PMID 21816004 DOI: 10.1111/j.1747-0285.2011.01204.x  0.64
2012 Magalhaes JG, Rubino SJ, Travassos LH, Le Bourhis L, Duan W, Sellge G, Geddes K, Reardon C, Lechmann M, Carneiro LA, Selvanantham T, Fritz JH, Taylor BC, Artis D, Mak T, ... ... Girardin SE, et al. Nucleotide oligomerization domain-containing proteins instruct T cell helper type 2 immunity through stromal activation (Proceedings of the National Academy of Sciences of the United States of America (2011) 108, 36 (14896-14901) DOI:10.1073/pnas.1015063108) Proceedings of the National Academy of Sciences of the United States of America. 109: 10605. DOI: 10.1073/pnas.1208781109  0.64
2011 Magalhaes JG, Rubino SJ, Travassos LH, Le Bourhis L, Duan W, Sellge G, Geddes K, Geddes K, Reardon C, Lechmann M, Carneiro LA, Selvanantham T, Fritz JH, Taylor BC, Artis D, ... ... Girardin SE, et al. Nucleotide oligomerization domain-containing proteins instruct T cell helper type 2 immunity through stromal activation. Proceedings of the National Academy of Sciences of the United States of America. 108: 14896-901. PMID 21856952 DOI: 10.1073/pnas.1015063108  0.64
2011 Arnoult D, Soares F, Tattoli I, Girardin SE. Mitochondria in innate immunity. Embo Reports. 12: 901-10. PMID 21799518 DOI: 10.1038/embor.2011.157  0.64
2011 Gareau MG, Ho NK, Brenner D, Sousa AJ, Lebourhis L, Mak TW, Girardin SE, Philpott DJ, Sherman PM. Enterohaemorrhagic, but not enteropathogenic, Escherichia coli infection of epithelial cells disrupts signalling responses to tumour necrosis factor-alpha. Microbiology (Reading, England). 157: 2963-73. PMID 21798984 DOI: 10.1099/mic.0.051094-0  0.64
2011 Geddes K, Rubino SJ, Magalhaes JG, Streutker C, Le Bourhis L, Cho JH, Robertson SJ, Kim CJ, Kaul R, Philpott DJ, Girardin SE. Identification of an innate T helper type 17 response to intestinal bacterial pathogens. Nature Medicine. 17: 837-44. PMID 21666695 DOI: 10.1038/nm.2391  0.64
2011 Werts C, Rubino S, Ling A, Girardin SE, Philpott DJ. Nod-like receptors in intestinal homeostasis, inflammation, and cancer. Journal of Leukocyte Biology. 90: 471-82. PMID 21653239 DOI: 10.1189/jlb.0411183  0.64
2011 Hakimi M, Selvanantham T, Swinton E, Padmore RF, Tong Y, Kabbach G, Venderova K, Girardin SE, Bulman DE, Scherzer CR, LaVoie MJ, Gris D, Park DS, Angel JB, Shen J, et al. Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures. Journal of Neural Transmission (Vienna, Austria : 1996). 118: 795-808. PMID 21552986 DOI: 10.1007/s00702-011-0653-2  0.64
2011 Magalhaes JG, Lee J, Geddes K, Rubino S, Philpott DJ, Girardin SE. Essential role of Rip2 in the modulation of innate and adaptive immunity triggered by Nod1 and Nod2 ligands. European Journal of Immunology. 41: 1445-55. PMID 21469090 DOI: 10.1002/eji.201040827  0.64
2011 Plantinga TS, Crisan TO, Oosting M, van de Veerdonk FL, de Jong DJ, Philpott DJ, van der Meer JW, Girardin SE, Joosten LA, Netea MG. Crohn's disease-associated ATG16L1 polymorphism modulates pro-inflammatory cytokine responses selectively upon activation of NOD2. Gut. 60: 1229-35. PMID 21406388 DOI: 10.1136/gut.2010.228908  0.64
2011 Sorbara MT, Girardin SE. Mitochondrial ROS fuel the inflammasome. Cell Research. 21: 558-60. PMID 21283134 DOI: 10.1038/cr.2011.20  0.64
2011 Magalhaes JG, Sorbara MT, Girardin SE, Philpott DJ. What is new with Nods? Current Opinion in Immunology. 23: 29-34. PMID 21190821 DOI: 10.1016/j.coi.2010.12.003  0.64
2010 Abdul-Sater AA, Saïd-Sadier N, Lam VM, Singh B, Pettengill MA, Soares F, Tattoli I, Lipinski S, Girardin SE, Rosenstiel P, Ojcius DM. Enhancement of reactive oxygen species production and chlamydial infection by the mitochondrial Nod-like family member NLRX1. The Journal of Biological Chemistry. 285: 41637-45. PMID 20959452 DOI: 10.1074/jbc.M110.137885  0.64
2010 Geddes K, Rubino S, Streutker C, Cho JH, Magalhaes JG, Le Bourhis L, Selvanantham T, Girardin SE, Philpott DJ. Nod1 and Nod2 regulation of inflammation in the Salmonella colitis model. Infection and Immunity. 78: 5107-15. PMID 20921147 DOI: 10.1128/IAI.00759-10  0.64
2010 Rubino S, Lee J, Girardin SE. Mammalian PGRPs also mind the fort. Cell Host & Microbe. 8: 130-2. PMID 20709290 DOI: 10.1016/j.chom.2010.07.010  0.64
2010 Roos FC, Roberts AM, Hwang II, Moriyama EH, Evans AJ, Sybingco S, Watson IR, Carneiro LA, Gedye C, Girardin SE, Ailles LE, Jewett MA, Milosevic M, Wilson BC, Bell JC, et al. Oncolytic targeting of renal cell carcinoma via encephalomyocarditis virus. Embo Molecular Medicine. 2: 275-88. PMID 20623734 DOI: 10.1002/emmm.201000081  0.64
2010 Benko S, Magalhaes JG, Philpott DJ, Girardin SE. NLRC5 limits the activation of inflammatory pathways. Journal of Immunology (Baltimore, Md. : 1950). 185: 1681-91. PMID 20610642 DOI: 10.4049/jimmunol.0903900  0.64
2010 Philpott DJ, Girardin SE. Nod-like receptors: sentinels at host membranes. Current Opinion in Immunology. 22: 428-34. PMID 20605429 DOI: 10.1016/j.coi.2010.04.010  0.64
2010 Philpott DJ, Girardin SE. Gut microbes extend reach to systemic innate immunity. Nature Medicine. 16: 160-1. PMID 20134466 DOI: 10.1038/nm0210-160  0.64
2010 Dharancy S, Body-Malapel M, Louvet A, Berrebi D, Gantier E, Gosset P, Viala J, Hollebecque A, Moreno C, Philpott DJ, Girardin SE, Sansonetti PJ, Desreumaux P, Mathurin P, Dubuquoy L. Neutrophil migration during liver injury is under nucleotide-binding oligomerization domain 1 control. Gastroenterology. 138: 1546-56, 1556.e1-5. PMID 20026116 DOI: 10.1053/j.gastro.2009.12.008  0.64
2010 Travassos LH, Carneiro LA, Ramjeet M, Hussey S, Kim YG, Magalhães JG, Yuan L, Soares F, Chea E, Le Bourhis L, Boneca IG, Allaoui A, Jones NL, Nuñez G, Girardin SE, et al. Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nature Immunology. 11: 55-62. PMID 19898471 DOI: 10.1038/ni.1823  0.64
2010 Kaparakis M, Turnbull L, Carneiro L, Firth S, Coleman HA, Parkington HC, Le Bourhis L, Karrar A, Viala J, Mak J, Hutton ML, Davies JK, Crack PJ, Hertzog PJ, Philpott DJ, ... Girardin SE, et al. Bacterial membrane vesicles deliver peptidoglycan to NOD1 in epithelial cells. Cellular Microbiology. 12: 372-85. PMID 19888989 DOI: 10.1111/j.1462-5822.2009.01404.x  0.64
2009 Girardin SE, Philpott DJ. Innate immunity: the connection with inflammation and disease. Seminars in Immunology. 21: 173-4. PMID 19699108 DOI: 10.1016/j.smim.2009.08.001  0.64
2009 Arnoult D, Soares F, Tattoli I, Castanier C, Philpott DJ, Girardin SE. An N-terminal addressing sequence targets NLRX1 to the mitochondrial matrix. Journal of Cell Science. 122: 3161-8. PMID 19692591 DOI: 10.1242/jcs.051193  0.64
2009 Le Bourhis L, Magalhaes JG, Selvanantham T, Travassos LH, Geddes K, Fritz JH, Viala J, Tedin K, Girardin SE, Philpott DJ. Role of Nod1 in mucosal dendritic cells during Salmonella pathogenicity island 1-independent Salmonella enterica serovar Typhimurium infection. Infection and Immunity. 77: 4480-6. PMID 19620349 DOI: 10.1128/IAI.00519-09  0.64
2009 Lee J, Tattoli I, Wojtal KA, Vavricka SR, Philpott DJ, Girardin SE. pH-dependent internalization of muramyl peptides from early endosomes enables Nod1 and Nod2 signaling. The Journal of Biological Chemistry. 284: 23818-29. PMID 19570976 DOI: 10.1074/jbc.M109.033670  0.64
2009 Girardin SE. Knocking in the NLRP3 inflammasome. Immunity. 30: 761-3. PMID 19538926 DOI: 10.1016/j.immuni.2009.06.001  0.64
2009 Arnoult D, Carneiro L, Tattoli I, Girardin SE. The role of mitochondria in cellular defense against microbial infection. Seminars in Immunology. 21: 223-32. PMID 19535268 DOI: 10.1016/j.smim.2009.05.009  0.64
2009 Geddes K, Magalhães JG, Girardin SE. Unleashing the therapeutic potential of NOD-like receptors. Nature Reviews. Drug Discovery. 8: 465-79. PMID 19483708 DOI: 10.1038/nrd2783  0.64
2009 Philpott DJ, Girardin SE. Crohn's disease-associated Nod2 mutants reduce IL10 transcription. Nature Immunology. 10: 455-7. PMID 19381138 DOI: 10.1038/ni0509-455  0.64
2009 Carneiro LA, Travassos LH, Soares F, Tattoli I, Magalhaes JG, Bozza MT, Plotkowski MC, Sansonetti PJ, Molkentin JD, Philpott DJ, Girardin SE. Shigella induces mitochondrial dysfunction and cell death in nonmyleoid cells. Cell Host & Microbe. 5: 123-36. PMID 19218084 DOI: 10.1016/j.chom.2008.12.011  0.64
2009 Le Bourhis L, Magalhaes JG, Selvanantham T, Travassos LH, Geddes K, Fritz JH, Viala J, Tedin K, Girardin SE, Philpott DJ. Role of Nod1 in mucosal dendritic cells during Salmonella pathogenicity island 1-independent Salmonella enterica serovar typhimurium infection (Infection and Immunity (2009) 77, 10 (4480-4486)) Infection and Immunity. 77: 5203. DOI: 10.1128/IAI.01067-09  0.64
2008 Magalhaes JG, Fritz JH, Le Bourhis L, Sellge G, Travassos LH, Selvanantham T, Girardin SE, Gommerman JL, Philpott DJ. Nod2-dependent Th2 polarization of antigen-specific immunity. Journal of Immunology (Baltimore, Md. : 1950). 181: 7925-35. PMID 19017983  0.64
2008 Benko S, Philpott DJ, Girardin SE. The microbial and danger signals that activate Nod-like receptors. Cytokine. 43: 368-73. PMID 18715799 DOI: 10.1016/j.cyto.2008.07.013  0.64
2008 Tattoli I, Lembo-Fazio L, Nigro G, Carneiro LA, Ferraro E, Rossi G, Martino MC, de Stefano ME, Cecconi F, Girardin SE, Philpott DJ, Bernardini ML. Intracellular bacteriolysis triggers a massive apoptotic cell death in Shigella-infected epithelial cells. Microbes and Infection / Institut Pasteur. 10: 1114-23. PMID 18606244 DOI: 10.1016/j.micinf.2008.06.004  0.64
2008 Joosten LA, Heinhuis B, Abdollahi-Roodsaz S, Ferwerda G, Lebourhis L, Philpott DJ, Nahori MA, Popa C, Morre SA, van der Meer JW, Girardin SE, Netea MG, van den Berg WB. Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis. Proceedings of the National Academy of Sciences of the United States of America. 105: 9017-22. PMID 18574154 DOI: 10.1073/pnas.0710445105  0.64
2008 Ting JP, Lovering RC, Alnemri ES, Bertin J, Boss JM, Davis BK, Flavell RA, Girardin SE, Godzik A, Harton JA, Hoffman HM, Hugot JP, Inohara N, Mackenzie A, Maltais LJ, et al. The NLR gene family: a standard nomenclature. Immunity. 28: 285-7. PMID 18341998 DOI: 10.1016/j.immuni.2008.02.005  0.64
2008 Body-Malapel M, Dharancy S, Berrebi D, Louvet A, Hugot JP, Philpott DJ, Giovannini M, Chareyre F, Pages G, Gantier E, Girardin SE, Garcia I, Hudault S, Conti F, Sansonetti PJ, et al. NOD2: a potential target for regulating liver injury. Laboratory Investigation; a Journal of Technical Methods and Pathology. 88: 318-27. PMID 18227809 DOI: 10.1038/labinvest.3700716  0.64
2008 Tattoli I, Carneiro LA, Jéhanno M, Magalhaes JG, Shu Y, Philpott DJ, Arnoult D, Girardin SE. NLRX1 is a mitochondrial NOD-like receptor that amplifies NF-kappaB and JNK pathways by inducing reactive oxygen species production. Embo Reports. 9: 293-300. PMID 18219313 DOI: 10.1038/sj.embor.7401161  0.64
2008 Ferwerda G, Kramer M, de Jong D, Piccini A, Joosten LA, Devesaginer I, Girardin SE, Adema GJ, van der Meer JW, Kullberg BJ, Rubartelli A, Netea MG. Engagement of NOD2 has a dual effect on proIL-1beta mRNA transcription and secretion of bioactive IL-1beta. European Journal of Immunology. 38: 184-91. PMID 18157816 DOI: 10.1002/eji.200737103  0.64
2007 Carneiro LA, Travassos LH, Girardin SE. Nod-like receptors in innate immunity and inflammatory diseases. Annals of Medicine. 39: 581-93. PMID 18038361 DOI: 10.1080/07853890701576172  0.64
2007 Le Bourhis L, Benko S, Girardin SE. Nod1 and Nod2 in innate immunity and human inflammatory disorders Biochemical Society Transactions. 35: 1479-1484. PMID 18031249 DOI: 10.1042/BST0351479  0.64
2007 Werts C, le Bourhis L, Liu J, Magalhaes JG, Carneiro LA, Fritz JH, Stockinger S, Balloy V, Chignard M, Decker T, Philpott DJ, Ma X, Girardin SE. Nod1 and Nod2 induce CCL5/RANTES through the NF-kappaB pathway. European Journal of Immunology. 37: 2499-508. PMID 17705131 DOI: 10.1002/eji.200737069  0.64
2007 Tattoli I, Travassos LH, Carneiro LA, Magalhaes JG, Girardin SE. The Nodosome: Nod1 and Nod2 control bacterial infections and inflammation. Seminars in Immunopathology. 29: 289-301. PMID 17690884 DOI: 10.1007/s00281-007-0083-2  0.64
2007 Ferwerda G, Kullberg BJ, de Jong DJ, Girardin SE, Langenberg DM, van Crevel R, Ottenhoff TH, Van der Meer JW, Netea MG. Mycobacterium paratuberculosis is recognized by Toll-like receptors and NOD2. Journal of Leukocyte Biology. 82: 1011-8. PMID 17652449 DOI: 10.1189/jlb.0307147  0.64
2007 Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ. Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity. Immunity. 26: 445-59. PMID 17433730 DOI: 10.1016/j.immuni.2007.03.009  0.64
2007 Magalhaes JG, Tattoli I, Girardin SE. The intestinal epithelial barrier: how to distinguish between the microbial flora and pathogens. Seminars in Immunology. 19: 106-15. PMID 17324587 DOI: 10.1016/j.smim.2006.12.006  0.64
2007 Ferrero-Miliani L, Nielsen OH, Andersen PS, Girardin SE. Chronic inflammation: Importance of NOD2 and NALP3 in interleukin-1β generation Clinical and Experimental Immunology. 147: 227-235. PMID 17223962 DOI: 10.1111/j.1365-2249.2006.03261.x  0.64
2007 Boneca IG, Dussurget O, Cabanes D, Nahori MA, Sousa S, Lecuit M, Psylinakis E, Bouriotis V, Hugot JP, Giovannini M, Coyle A, Bertin J, Namane A, Rousselle JC, Cayet N, ... ... Girardin SE, et al. A critical role for peptidoglycan N-deacetylation in Listeria evasion from the host innate immune system. Proceedings of the National Academy of Sciences of the United States of America. 104: 997-1002. PMID 17215377 DOI: 10.1073/pnas.0609672104  0.64
2006 Ismair MG, Vavricka SR, Kullak-Ublick GA, Fried M, Mengin-Lecreulx D, Girardin SE. hPepT1 selectively transports muramyl dipeptide but not Nod1-activating muramyl peptides. Canadian Journal of Physiology and Pharmacology. 84: 1313-9. PMID 17487240 DOI: 10.1139/y06-076  0.64
2006 Fritz JH, Ferrero RL, Philpott DJ, Girardin SE. Nod-like proteins in immunity, inflammation and disease. Nature Immunology. 7: 1250-7. PMID 17110941 DOI: 10.1038/ni1412  0.64
2006 Ferwerda G, Girardin SE, van der Meer JW, Netea MG. Normal responses to specific NOD1 ligands. European Journal of Immunology. 36: 2817-8; author reply. PMID 17013977 DOI: 10.1002/eji.200636332  0.64
2006 Chaput C, Ecobichon C, Cayet N, Girardin SE, Werts C, Guadagnini S, Prévost MC, Mengin-Lecreulx D, Labigne A, Boneca IG. Role of AmiA in the morphological transition of Helicobacter pylori and in immune escape. Plos Pathogens. 2: e97. PMID 17002496 DOI: 10.1371/journal.ppat.0020097  0.64
2006 Netea MG, Azam T, Ferwerda G, Girardin SE, Kim SH, Dinarello CA. Triggering receptor expressed on myeloid cells-1 (TREM-1) amplifies the signals induced by the NACHT-LRR (NLR) pattern recognition receptors. Journal of Leukocyte Biology. 80: 1454-61. PMID 16940328 DOI: 10.1189/jlb.1205758  0.64
2006 Fritz JH, Girardin SE, Philpott DJ. Innate immune defense through RNA interference. Science's Stke : Signal Transduction Knowledge Environment. 2006: pe27. PMID 16772641 DOI: 10.1126/stke.3392006pe27  0.64
2006 Girardin SE, Philpott DJ. PGRP-LB minds the fort. Immunity. 24: 363-6. PMID 16618594 DOI: 10.1016/j.immuni.2006.04.001  0.64
2006 Werts C, Girardin SE, Philpott DJ. TIR, CARD and PYRIN: Three domains for an antimicrobial triad Cell Death and Differentiation. 13: 798-815. PMID 16528382 DOI: 10.1038/sj.cdd.4401890  0.64
2006 van der Graaf CA, Netea MG, Franke B, Girardin SE, van der Meer JW, Kullberg BJ. Nucleotide oligomerization domain 2 (Nod2) is not involved in the pattern recognition of Candida albicans. Clinical and Vaccine Immunology : Cvi. 13: 423-5. PMID 16522788 DOI: 10.1128/CVI.13.3.423-425.2006  0.64
2006 Tien MT, Girardin SE, Regnault B, Le Bourhis L, Dillies MA, Coppée JY, Bourdet-Sicard R, Sansonetti PJ, Pédron T. Anti-inflammatory effect of Lactobacillus casei on Shigella-infected human intestinal epithelial cells. Journal of Immunology (Baltimore, Md. : 1950). 176: 1228-37. PMID 16394013  0.64
2005 Ferwerda G, Girardin SE, Kullberg BJ, Le Bourhis L, de Jong DJ, Langenberg DM, van Crevel R, Adema GJ, Ottenhoff TH, Van der Meer JW, Netea MG. NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis. Plos Pathogens. 1: 279-85. PMID 16322770 DOI: 10.1371/journal.ppat.0010034  0.64
2005 Fritz JH, Girardin SE. How Toll-like receptors and Nod-like receptors contribute to innate immunity in mammals. Journal of Endotoxin Research. 11: 390-4. PMID 16303096 DOI: 10.1179/096805105X76850  0.64
2005 Netea MG, Azam T, Ferwerda G, Girardin SE, Walsh M, Park JS, Abraham E, Kim JM, Yoon DY, Dinarello CA, Kim SH. IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1beta and IL-6 production through a caspase 1-dependent mechanism. Proceedings of the National Academy of Sciences of the United States of America. 102: 16309-14. PMID 16260731 DOI: 10.1073/pnas.0508237102  0.64
2005 Magalhaes JG, Philpott DJ, Nahori MA, Jéhanno M, Fritz J, Le Bourhis L, Viala J, Hugot JP, Giovannini M, Bertin J, Lepoivre M, Mengin-Lecreulx D, Sansonetti PJ, Girardin SE. Murine Nod1 but not its human orthologue mediates innate immune detection of tracheal cytotoxin. Embo Reports. 6: 1201-7. PMID 16211083 DOI: 10.1038/sj.embor.7400552  0.64
2005 Netea MG, Ferwerda G, de Jong DJ, Girardin SE, Kullberg BJ, van der Meer JW. NOD2 3020insC mutation and the pathogenesis of Crohn's disease: impaired IL-1beta production points to a loss-of-function phenotype. The Netherlands Journal of Medicine. 63: 305-8. PMID 16186640  0.64
2005 Girardin SE, Jéhanno M, Mengin-Lecreulx D, Sansonetti PJ, Alzari PM, Philpott DJ. Identification of the critical residues involved in peptidoglycan detection by Nod1. The Journal of Biological Chemistry. 280: 38648-56. PMID 16172124 DOI: 10.1074/jbc.M509537200  0.64
2005 Travassos LH, Carneiro LA, Girardin SE, Boneca IG, Lemos R, Bozza MT, Domingues RC, Coyle AJ, Bertin J, Philpott DJ, Plotkowski MC. Nod1 participates in the innate immune response to Pseudomonas aeruginosa. The Journal of Biological Chemistry. 280: 36714-8. PMID 16150702 DOI: 10.1074/jbc.M501649200  0.64
2005 Netea MG, Ferwerda G, de Jong DJ, Werts C, Boneca IG, Jéhanno M, Van Der Meer JW, Mengin-Lecreulx D, Sansonetti PJ, Philpott DJ, Dharancy S, Girardin SE. The frameshift mutation in Nod2 results in unresponsiveness not only to Nod2- but also Nod1-activating peptidoglycan agonists. The Journal of Biological Chemistry. 280: 35859-67. PMID 16115863 DOI: 10.1074/jbc.M504924200  0.64
2005 Fritz JH, Girardin SE, Fitting C, Werts C, Mengin-Lecreulx D, Caroff M, Cavaillon JM, Philpott DJ, Adib-Conquy M. Synergistic stimulation of human monocytes and dendritic cells by Toll-like receptor 4 and NOD1- and NOD2-activating agonists. European Journal of Immunology. 35: 2459-70. PMID 16021602 DOI: 10.1002/eji.200526286  0.64
2005 Netea MG, Ferwerda G, de Jong DJ, Jansen T, Jacobs L, Kramer M, Naber TH, Drenth JP, Girardin SE, Kullberg BJ, Adema GJ, Van der Meer JW. Nucleotide-binding oligomerization domain-2 modulates specific TLR pathways for the induction of cytokine release. Journal of Immunology (Baltimore, Md. : 1950). 174: 6518-23. PMID 15879155  0.64
2004 Viala J, Chaput C, Boneca IG, Cardona A, Girardin SE, Moran AP, Athman R, Mémet S, Huerre MR, Coyle AJ, DiStefano PS, Sansonetti PJ, Labigne A, Bertin J, Philpott DJ, et al. Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nature Immunology. 5: 1166-74. PMID 15489856 DOI: 10.1038/ni1131  0.64
2004 Philpott DJ, Girardin SE. The role of Toll-like receptors and Nod proteins in bacterial infection. Molecular Immunology. 41: 1099-108. PMID 15476921 DOI: 10.1016/j.molimm.2004.06.012  0.64
2004 Travassos LH, Girardin SE, Philpott DJ, Blanot D, Nahori MA, Werts C, Boneca IG. Toll-like receptor 2-dependent bacterial sensing does not occur via peptidoglycan recognition. Embo Reports. 5: 1000-6. PMID 15359270 DOI: 10.1038/sj.embor.7400248  0.64
2004 Bougnères L, Girardin SE, Weed SA, Karginov AV, Olivo-Marin JC, Parsons JT, Sansonetti PJ, Van Nhieu GT. Cortactin and Crk cooperate to trigger actin polymerization during Shigella invasion of epithelial cells. The Journal of Cell Biology. 166: 225-35. PMID 15263018 DOI: 10.1083/jcb.200402073  0.64
2004 Girardin SE, Philpott DJ. Mini-review: the role of peptidoglycan recognition in innate immunity. European Journal of Immunology. 34: 1777-82. PMID 15214025 DOI: 10.1002/eji.200425095  0.64
2003 Girardin SE, Hugot JP, Sansonetti PJ. Lessons from Nod2 studies: towards a link between Crohn's disease and bacterial sensing. Trends in Immunology. 24: 652-8. PMID 14644139 DOI: 10.1016/j.it.2003.10.007  0.64
2003 Girardin SE, Philpott DJ, Lemaitre B. Sensing microbes by diverse hosts. Workshop on pattern recognition proteins and receptors. Embo Reports. 4: 932-6. PMID 14502224 DOI: 10.1038/sj.embor.embor940  0.64
2003 Chamaillard M, Girardin SE, Viala J, Philpott DJ. Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation. Cellular Microbiology. 5: 581-92. PMID 12925128 DOI: 10.1046/j.1462-5822.2003.00304.x  0.64
2003 Girardin SE, Travassos LH, Hervé M, Blanot D, Boneca IG, Philpott DJ, Sansonetti PJ, Mengin-Lecreulx D. Peptidoglycan molecular requirements allowing detection by Nod1 and Nod2. The Journal of Biological Chemistry. 278: 41702-8. PMID 12871942 DOI: 10.1074/jbc.M307198200  0.64
2003 Girardin SE, Boneca IG, Carneiro LA, Antignac A, Jéhanno M, Viala J, Tedin K, Taha MK, Labigne A, Zähringer U, Coyle AJ, DiStefano PS, Bertin J, Sansonetti PJ, Philpott DJ. Nod1 detects a unique muropeptide from gram-negative bacterial peptidoglycan. Science (New York, N.Y.). 300: 1584-7. PMID 12791997 DOI: 10.1126/science.1084677  0.64
2003 Chamaillard M, Philpott D, Girardin SE, Zouali H, Lesage S, Chareyre F, Bui TH, Giovannini M, Zaehringer U, Penard-Lacronique V, Sansonetti PJ, Hugot JP, Thomas G. Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases. Proceedings of the National Academy of Sciences of the United States of America. 100: 3455-60. PMID 12626759 DOI: 10.1073/pnas.0530276100  0.64
2003 Girardin SE, Boneca IG, Viala J, Chamaillard M, Labigne A, Thomas G, Philpott DJ, Sansonetti PJ. Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection. The Journal of Biological Chemistry. 278: 8869-72. PMID 12527755 DOI: 10.1074/jbc.C200651200  0.64
2002 Girardin SE, Sansonetti PJ, Philpott DJ. Intracellular vs extracellular recognition of pathogens--common concepts in mammals and flies. Trends in Microbiology. 10: 193-9. PMID 11912027 DOI: 10.1016/S0966-842X(02)02334-X  0.64
2001 Philpott DJ, Girardin SE, Sansonetti PJ. Innate immune responses of epithelial cells following infection with bacterial pathogens Current Opinion in Immunology. 13: 410-416. PMID 11498296 DOI: 10.1016/S0952-7915(00)00235-1  0.64
2001 Girardin SE, Tournebize R, Mavris M, Page AL, Li X, Stark GR, Bertin J, DiStefano PS, Yaniv M, Sansonetti PJ, Philpott DJ. CARD4/Nod1 mediates NF-kappaB and JNK activation by invasive Shigella flexneri. Embo Reports. 2: 736-42. PMID 11463746 DOI: 10.1093/embo-reports/kve155  0.64
2001 Girardin SE, Yaniv M. A direct interaction between JNK1 and CrkII is critical for Rac1-induced JNK activation Embo Journal. 20: 3437-3446. PMID 11432831 DOI: 10.1093/emboj/20.13.3437  0.64
1998 Girardin SE, Benjannet S, Barale JC, Chrétien M, Seidah NG. The LIM homeobox protein mLIM3/Lhx3 induces expression of the prolactin gene by a Pit-1/GHF-1-independent pathway in corticotroph AtT20 cells Febs Letters. 431: 333-338. PMID 9714537 DOI: 10.1016/S0014-5793(98)00787-X  0.64
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