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Lea Brakier-Gingras - Publications

Affiliations: 
Biochemistry Université de Montréal, Montréal, Canada 
Area:
Virology Biology
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58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Del Toro N, Lessard F, Bouchard J, Mobasheri N, Guillon J, Igelmann S, Tardif S, Buffard T, Bourdeau V, Brakier-Gingras L, Ferbeyre G. Cellular Senescence limits Translational Readthrough. Biology Open. PMID 34676390 DOI: 10.1242/bio.058688  0.613
2019 Del Toro N, Fernandez-Ruiz A, Mignacca L, Kalegari P, Rowell MC, Igelmann S, Saint-Germain E, Benfdil M, Lopes-Paciencia S, Brakier-Gingras L, Bourdeau V, Ferbeyre G, Lessard F. Ribosomal protein Rpl22/eL22 regulates the cell cycle by acting as an inhibitor of the CDK4-cyclin D complex. Cell Cycle (Georgetown, Tex.). PMID 30874462 DOI: 10.1080/15384101.2019.1593708  0.655
2019 Lessard F, Brakier-Gingras L, Ferbeyre G. Ribosomal Proteins Control Tumor Suppressor Pathways in Response to Nucleolar Stress. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. e1800183. PMID 30706966 DOI: 10.1002/Bies.201800183  0.329
2018 Lessard F, Igelmann S, Trahan C, Huot G, Saint-Germain E, Mignacca L, Del Toro N, Lopes-Paciencia S, Le Calvé B, Montero M, Deschênes-Simard X, Bury M, Moiseeva O, Rowell MC, Zorca CE, ... ... Brakier-Gingras L, et al. Senescence-associated ribosome biogenesis defects contributes to cell cycle arrest through the Rb pathway. Nature Cell Biology. PMID 29941930 DOI: 10.1038/S41556-018-0127-Y  0.661
2012 Brakier-Gingras L, Charbonneau J, Butcher SE. Targeting frameshifting in the human immunodeficiency virus. Expert Opinion On Therapeutic Targets. 16: 249-58. PMID 22404160 DOI: 10.1517/14728222.2012.665879  0.622
2012 Charbonneau J, Gendron K, Ferbeyre G, Brakier-Gingras L. The 5' UTR of HIV-1 full-length mRNA and the Tat viral protein modulate the programmed -1 ribosomal frameshift that generates HIV-1 enzymes. Rna (New York, N.Y.). 18: 519-29. PMID 22286970 DOI: 10.1261/Rna.030346.111  0.64
2012 Knops E, Brakier-Gingras L, Schülter E, Pfister H, Kaiser R, Verheyen J. Mutational patterns in the frameshift-regulating site of HIV-1 selected by protease inhibitors. Medical Microbiology and Immunology. 201: 213-8. PMID 22200908 DOI: 10.1007/S00430-011-0224-Z  0.388
2011 Gendron K, Ferbeyre G, Heveker N, Brakier-Gingras L. The activity of the HIV-1 IRES is stimulated by oxidative stress and controlled by a negative regulatory element. Nucleic Acids Research. 39: 902-12. PMID 20935056 DOI: 10.1093/Nar/Gkq885  0.421
2010 Knops E, Däumer M, Awerkiew S, Kartashev V, Schülter E, Kutsev S, Brakier-Gingras L, Kaiser R, Pfister H, Verheyen J. Evolution of protease inhibitor resistance in the gag and pol genes of HIV subtype G isolates. The Journal of Antimicrobial Chemotherapy. 65: 1472-6. PMID 20430786 DOI: 10.1093/Jac/Dkq129  0.343
2008 Dulude D, Théberge-Julien G, Brakier-Gingras L, Heveker N. Selection of peptides interfering with a ribosomal frameshift in the human immunodeficiency virus type 1. Rna (New York, N.Y.). 14: 981-91. PMID 18367719 DOI: 10.1261/Rna.887008  0.38
2008 Gendron K, Charbonneau J, Dulude D, Heveker N, Ferbeyre G, Brakier-Gingras L. The presence of the TAR RNA structure alters the programmed -1 ribosomal frameshift efficiency of the human immunodeficiency virus type 1 (HIV-1) by modifying the rate of translation initiation. Nucleic Acids Research. 36: 30-40. PMID 17984074 DOI: 10.1093/Nar/Gkm906  0.655
2007 Léger M, Dulude D, Steinberg SV, Brakier-Gingras L. The three transfer RNAs occupying the A, P and E sites on the ribosome are involved in viral programmed -1 ribosomal frameshift. Nucleic Acids Research. 35: 5581-92. PMID 17704133 DOI: 10.1093/Nar/Gkm578  0.442
2007 Nijhuis M, van Maarseveen NM, Lastere S, Schipper P, Coakley E, Glass B, Rovenska M, de Jong D, Chappey C, Goedegebuure IW, Heilek-Snyder G, Dulude D, Cammack N, Brakier-Gingras L, Konvalinka J, et al. A novel substrate-based HIV-1 protease inhibitor drug resistance mechanism. Plos Medicine. 4: e36. PMID 17227139 DOI: 10.1371/Journal.Pmed.0040036  0.328
2006 Dulude D, Brakier-Gingras L. [The structure of the frameshift stimulatory signal in HIV-1 RNA: a potential target for the treatment of patients infected with HIV]. MéDecine Sciences : M/S. 22: 969-72. PMID 17101099 DOI: 10.1051/Medsci/20062211969  0.404
2006 Dulude D, Berchiche YA, Gendron K, Brakier-Gingras L, Heveker N. Decreasing the frameshift efficiency translates into an equivalent reduction of the replication of the human immunodeficiency virus type 1. Virology. 345: 127-36. PMID 16256163 DOI: 10.1016/J.Virol.2005.08.048  0.363
2005 Bélanger F, Théberge-Julien G, Cunningham PR, Brakier-Gingras L. A functional relationship between helix 1 and the 900 tetraloop of 16S ribosomal RNA within the bacterial ribosome. Rna (New York, N.Y.). 11: 906-13. PMID 15872184 DOI: 10.1261/Rna.2160405  0.418
2005 Gendron K, Dulude D, Lemay G, Ferbeyre G, Brakier-Gingras L. The virion-associated Gag-Pol is decreased in chimeric Moloney murine leukemia viruses in which the readthrough region is replaced by the frameshift region of the human immunodeficiency virus type 1. Virology. 334: 342-52. PMID 15780884 DOI: 10.1016/J.Virol.2005.01.044  0.417
2005 Baril M, Brakier-Gingras L. Translation of the F protein of hepatitis C virus is initiated at a non-AUG codon in a +1 reading frame relative to the polyprotein. Nucleic Acids Research. 33: 1474-86. PMID 15755749 DOI: 10.1093/Nar/Gki292  0.34
2005 Grisé-Miron L, Brakier-Gingras L. Effect of neomycin and protein S1 on the binding of streptomycin to the ribosome. Febs Journal. 123: 643-646. PMID 6176448 DOI: 10.1111/J.1432-1033.1982.Tb06580.X  0.381
2004 Léger M, Sidani S, Brakier-Gingras L. A reassessment of the response of the bacterial ribosome to the frameshift stimulatory signal of the human immunodeficiency virus type 1. Rna (New York, N.Y.). 10: 1225-35. PMID 15247429 DOI: 10.1261/Rna.7670704  0.454
2004 Bélanger F, Gagnon MG, Steinberg SV, Cunningham PR, Brakier-Gingras L. Study of the functional interaction of the 900 Tetraloop of 16S ribosomal RNA with helix 24 within the bacterial ribosome. Journal of Molecular Biology. 338: 683-93. PMID 15099737 DOI: 10.1016/J.Jmb.2004.03.024  0.414
2003 Baril M, Dulude D, Gendron K, Lemay G, Brakier-Gingras L. Efficiency of a programmed -1 ribosomal frameshift in the different subtypes of the human immunodeficiency virus type 1 group M. Rna (New York, N.Y.). 9: 1246-53. PMID 13130138 DOI: 10.1261/Rna.5113603  0.328
2003 Robert F, Brakier-Gingras L. A functional interaction between ribosomal proteins S7 and S11 within the bacterial ribosome. The Journal of Biological Chemistry. 278: 44913-20. PMID 12937172 DOI: 10.1074/Jbc.M306534200  0.61
2003 Baril M, Dulude D, Steinberg SV, Brakier-Gingras L. The frameshift stimulatory signal of human immunodeficiency virus type 1 group O is a pseudoknot. Journal of Molecular Biology. 331: 571-83. PMID 12899829 DOI: 10.1016/S0022-2836(03)00784-8  0.335
2003 Brunelle MN, Brakier-Gingras L, Lemay G. Replacement of murine leukemia virus readthrough mechanism by human immunodeficiency virus frameshift allows synthesis of viral proteins and virus replication. Journal of Virology. 77: 3345-50. PMID 12584361 DOI: 10.1128/Jvi.77.5.3345-3350.2003  0.337
2002 Bélanger F, Léger M, Saraiya AA, Cunningham PR, Brakier-Gingras L. Functional studies of the 900 tetraloop capping helix 27 of 16S ribosomal RNA. Journal of Molecular Biology. 320: 979-89. PMID 12126619 DOI: 10.1016/S0022-2836(02)00550-8  0.407
2001 Robert F, Brakier-Gingras L. Ribosomal protein S7 from Escherichia coli uses the same determinants to bind 16S ribosomal RNA and its messenger RNA. Nucleic Acids Research. 29: 677-82. PMID 11160889 DOI: 10.1093/Nar/29.3.677  0.638
2000 Robert F, Gagnon M, Sans D, Michnick S, Brakier-Gingras L. Mapping of the RNA recognition site of Escherichia coli ribosomal protein S7 Rna. 6: 1649-1659. PMID 11105763 DOI: 10.1017/S1355838200001199  0.618
1999 Brunelle MN, Payant C, Lemay G, Brakier-Gingras L. Expression of the human immunodeficiency virus frameshift signal in a bacterial cell-free system: Influence of an interaction between the ribosome and a stem-loop structure downstream from the slippery site Nucleic Acids Research. 27: 4783-4791. PMID 10572179 DOI: 10.1093/Nar/27.24.4783  0.451
1998 Montpetit A, Payant C, Nolan JM, Brakier-Gingras L. Analysis of the conformation of the 3' major domain of Escherichia coli16S ribosomal RNA using site-directed photoaffinity crosslinking. Rna (New York, N.Y.). 4: 1455-66. PMID 9814765 DOI: 10.1017/S1355838298981079  0.408
1998 Doyon L, Payant C, Brakier-Gingras L, Lamarre D. Novel Gag-Pol frameshift site in human immunodeficiency virus type 1 variants resistant to protease inhibitors. Journal of Virology. 72: 6146-50. PMID 9621079 DOI: 10.1128/Jvi.72.7.6146-6150.1998  0.403
1997 Spickler C, Brunelle MN, Brakier-Gingras L. Streptomycin binds to the decoding center of 16S ribosomal RNA Journal of Molecular Biology. 273: 586-599. PMID 9356248 DOI: 10.1006/Jmbi.1997.1323  0.386
1995 Brakier-Gingras L, Pinard R, Dragon F. Pleiotropic effects of mutations at positions 13 and 914 in Escherichia coli 16S ribosomal RNA. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 73: 907-13. PMID 8722006 DOI: 10.1139/O95-098  0.458
1995 Pinard R, Payant C, Brakier-Gingras L. Mutations at positions 13 and/or 914 in Escherichia coli 16S ribosomal RNA interfere with the initiation of protein synthesis. Biochemistry. 34: 9611-6. PMID 7626629 DOI: 10.1021/Bi00029A038  0.459
1994 Beaulieu M, Ouellette M, Desgroseillers L, Brakier-Gingras L. Molecular cloning and characterization of the hamster preproenkephalin A cDNA Dna and Cell Biology. 13: 933-940. PMID 7917015 DOI: 10.1089/Dna.1994.13.933  0.344
1994 Dragon F, Payant C, Brakier-Gingras L. Mutational and structural analysis of the RNA binding site for Escherichia coli ribosomal protein S7. Journal of Molecular Biology. 244: 74-85. PMID 7525976 DOI: 10.1006/Jmbi.1994.1705  0.392
1994 Pinard R, Côté M, Payant C, Brakier-Gingras L. Positions 13 and 914 in Escherichia coli 16S ribosomal RNA are involved in the control of translational accuracy. Nucleic Acids Research. 22: 619-24. PMID 7510397 DOI: 10.1093/Nar/22.4.619  0.428
1993 Dragon F, Brakier-Gingras L. Interaction of Escherichia coli ribosomal protein S7 with 16S rRNA. Nucleic Acids Research. 21: 1199-203. PMID 7681943 DOI: 10.1093/Nar/21.5.1199  0.426
1993 Pinard R, Payant C, Melançon P, Brakier-Gingras L. The 5' proximal helix of 16S rRNA is involved in the binding of streptomycin to the ribosome. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 7: 173-6. PMID 7678560  0.317
1992 Melançon P, Tapprich WE, Brakier-Gingras L. Single-base mutations at position 2661 of Escherichia coli 23S rRNA increase efficiency of translational proofreading. Journal of Bacteriology. 174: 7896-901. PMID 1281147  0.32
1991 Leclerc D, Brakier-Gingras L. A conformational switch involving the 915 region of Escherichia coli 16 S ribosomal RNA Febs Letters. 279: 171-174. PMID 2001727 DOI: 10.1016/0014-5793(91)80141-O  0.44
1991 Leclerc D, Melançon P, Brakier-Gingras L. The interaction between streptomycin and ribosomal RNA Biochimie. 73: 1431-1438. PMID 1725256 DOI: 10.1016/0300-9084(91)90175-Z  0.443
1991 Leclerc D, Melancon P, Brakier-gingras L. Mutations in the 915 region of Escherichia coli 16S ribosomal RNA reduce the binding of streptomycin to the ribosome Nucleic Acids Research. 19: 3973-3977. PMID 1713666 DOI: 10.1093/Nar/19.14.3973  0.449
1990 Melançon P, Leclerc D, Brakier-Gingras L. A deletion mutation at the 5′ end of Escherichia coli 16S ribosomal RNA Bba - Gene Structure and Expression. 1050: 98-103. PMID 2207175 DOI: 10.1016/0167-4781(90)90148-U  0.48
1990 Melançon P, Leclerc D, Destroismaisons N, Brakier-Gingras L. The anti-shine-dalgarno region in Escherichia coli 16S ribosomal RNA is not essential for the correct selection of translational starts Biochemistry. 29: 3402-3407. PMID 2185838 DOI: 10.1021/Bi00465A037  0.471
1990 Leclerc D, Brakier-Gingras L. Study of the function of Escherichia coli ribosomal RNA through site-directed mutagenesis Biochemistry and Cell Biology. 68: 169-179. PMID 1693518 DOI: 10.1139/O90-023  0.444
1989 Gravel M, Leclerc D, Melançon P, Brakier-Gingras L. The conserved 900 stem/loop region in Escherichia coli 16S ribosomal RNA is not required for protein synthesis. Nucleic Acids Research. 17: 2723-32. PMID 2654884 DOI: 10.1093/Nar/17.7.2723  0.441
1988 Ouellette M, Brakier-Gingras L. Increase in the relative abundance of preproenkephalin A messenger RNA in the ventricles of cardiomyopathic hamsters Biochemical and Biophysical Research Communications. 155: 449-454. PMID 3415700 DOI: 10.1016/S0006-291X(88)81107-0  0.314
1988 Melançon P, Lemieux C, Brakier-Gingras L. A mutation in the 530 loop of Escherichia coli 16S ribosomal RNA causes resistance to streptomycin. Nucleic Acids Research. 16: 9631-9. PMID 3054810 DOI: 10.1093/Nar/16.20.9631  0.447
1987 Ouellette M, Jolicoeur C, Brakier-Gingras L. Changes in the messenger RNA population from the heart of cardiomyopathic hamsters Journal of Molecular and Cellular Cardiology. 19: 709-717. PMID 3682008 DOI: 10.1016/S0022-2828(87)80379-6  0.305
1987 Melançon P, Gravel M, Boileau G, Brakier-Gingras L. Reassembly of active 30S ribosomal subunits with an unmethylated in vitro transcribed 16S rRNA. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 65: 1022-30. PMID 3331285 DOI: 10.1139/O87-134  0.606
1987 Gravel M, Melançon P, Brakier-Gingras L. Cross-linking of streptomycin to the 16S ribosomal RNA of Escherichia coli. Biochemistry. 26: 6227-32. PMID 2446658 DOI: 10.1021/Bi00393A041  0.394
1984 Melançon P, Boileau G, Brakier-Gingras L. Cross-linking of streptomycin to the 30S subunit of Escherichia coli with phenyldiglyoxal Biochemistry. 23: 6697-6703. PMID 6085011 DOI: 10.1021/Bi00321A064  0.618
1983 Jolicoeur C, Noël J, Brakier-Gingras L. The 60S ribosomal subunit is altered in the skeletal muscle of dystrophic hamsters. Biochemical and Biophysical Research Communications. 115: 153-8. PMID 6615523 DOI: 10.1016/0006-291X(83)90982-8  0.387
1983 Phoenix P, Melançon P, Brakier-Gingras L. Characterization of mutants of Escherichia coli with an increased control of translation fidelity Mgg Molecular &Amp; General Genetics. 189: 123-128. PMID 6343779 DOI: 10.1007/Bf00326064  0.399
1981 Grisé-Miron L, Noreau J, Melançon P, Brakier-Gingras L. Comparison of the misreading induced by streptomycin and neomycin. Biochimica Et Biophysica Acta. 656: 103-10. PMID 6796121 DOI: 10.1016/0005-2787(81)90032-0  0.406
1980 Noreau J, Grisé-Miron L, Brakier-Gingras L. Comparison of the action of streptomycin and neomycin on the structure of the bacterial ribosome Bba Section Nucleic Acids and Protein Synthesis. 608: 72-81. PMID 6248117 DOI: 10.1016/0005-2787(80)90135-5  0.327
1977 Lacoste L, Lacaille M, Brakier-Gingras L. The role of misrepair processes in the isolation of new types of streptomycin-resistant mutants in Escherichia coli Mgg Molecular &Amp; General Genetics. 157: 313-318. PMID 340928 DOI: 10.1007/Bf00268668  0.304
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