| Year |
Citation |
Score |
| 2020 |
Ding L, Li Q, Chakrabarti J, Munoz A, Faure-Kumar E, Ocadiz-Ruiz R, Razumilava N, Zhang G, Hayes MH, Sontz RA, Mendoza ZE, Mahurkar S, Greenson JK, Perez-Perez G, Hanh NTH, ... ... Iliopoulos D, et al. MiR130b from Schlafen4 MDSCs stimulates epithelial proliferation and correlates with preneoplastic changes prior to gastric cancer. Gut. PMID 31980446 DOI: 10.1136/Gutjnl-2019-318817 |
0.333 |
|
| 2020 |
Polytarchou C, Hatziapostolou M, Koutsioumpa M, Christodoulou N, Yau TO, Birli E, Pomenya O, Montiel-Duarte C, Joshi SM, Hommes DW, Verspaget HW, Yu J, Iliopoulos D. Abstract LB-184: A lncRNA-histone acetyltransferase complex induces colorectal oncogenesis through regulation of a metabolic kinase network Cancer Research. 80. DOI: 10.1158/1538-7445.Am2020-Lb-184 |
0.386 |
|
| 2019 |
Bakirtzi K, Law IKM, Fang K, Iliopoulos D, Pothoulakis C. MiR-21 in Substance P-induced exosomes promotes cell proliferation and migration in human colonic epithelial cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. PMID 31545921 DOI: 10.1152/Ajpgi.00043.2019 |
0.333 |
|
| 2019 |
Soroosh A, Rankin CR, Polytarchou C, Lokhandwala ZA, Patel A, Chang L, Pothoulakis C, Iliopoulos D, Padua DM. microRNA-24 Is Elevated in Ulcerative Colitis Patients and Regulates Intestinal Epithelial Barrier Function. The American Journal of Pathology. PMID 31220450 DOI: 10.1016/J.Ajpath.2019.05.018 |
0.366 |
|
| 2019 |
Fang K, Law IKM, Neman S, Iliopoulos D, Pothoulakis C. Mo1117 – Gavage As-Mir-214-3P Reduces Inflammation in Experimental Colitis Gastroenterology. 156: S-711-S-712. DOI: 10.1016/S0016-5085(19)38714-1 |
0.31 |
|
| 2018 |
Koutsioumpa M, Hatziapostolou M, Polytarchou C, Tolosa EJ, Almada LL, Mahurkar-Joshi S, Williams J, Tirado-Rodriguez AB, Huerta-Yepez S, Karavias D, Kourea H, Poultsides GA, Struhl K, Dawson DW, Donahue TR, ... ... Iliopoulos D, et al. Lysine methyltransferase 2D regulates pancreatic carcinogenesis through metabolic reprogramming. Gut. PMID 30337373 DOI: 10.1136/Gutjnl-2017-315690 |
0.306 |
|
| 2018 |
Koutsioumpa M, Chen HW, O'Brien N, Koinis F, Mahurkar-Joshi S, Vorvis C, Soroosh A, Luo T, Issakhanian S, Pantuck AJ, Georgoulias V, Iliopoulos D, Slamon DJ, Drakaki A. MKAD-21 suppresses the oncogenic activity of the miR-21/PPP2R2A/ERK molecular network in bladder cancer. Molecular Cancer Therapeutics. PMID 29703843 DOI: 10.1158/1535-7163.Mct-17-1049 |
0.391 |
|
| 2018 |
Soroosh A, Law IKM, Koutsioumpa M, Pothoulakis C, Iliopoulos D. Su1664 - Histone Deacetylase 7 Expression is Upregulated in Colonic Tissues from DSS-Induced Colitis Mice and from Patients with Active Ulcerative Colitis Gastroenterology. 154: S-567. DOI: 10.1016/S0016-5085(18)32086-9 |
0.302 |
|
| 2017 |
Fang K, Law IKM, Padua D, Sideri A, Huang V, Kevil CG, Iliopoulos D, Pothoulakis C. MicroRNA-31-3p Is Involved in Substance P (SP)-Associated Inflammation in Human Colonic Epithelial Cells and Experimental Colitis. The American Journal of Pathology. PMID 29253460 DOI: 10.1016/J.Ajpath.2017.10.023 |
0.368 |
|
| 2017 |
Soroosh A, Koutsioumpa M, Pothoulakis C, Iliopoulos D. Functional role and therapeutic targeting of microRNAs in Inflammatory Bowel Disease. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00268.2017. PMID 29146677 DOI: 10.1152/Ajpgi.00268.2017 |
0.301 |
|
| 2017 |
Fulcher JA, Koukos G, Koutsioumpa M, Elliott J, Drakaki A, Iliopoulos D, Anton PA. Unique microRNA Expression in the Colonic Mucosa During Chronic HIV-1 Infection. Aids (London, England). PMID 28692540 DOI: 10.1097/Qad.0000000000001582 |
0.314 |
|
| 2017 |
Drakaki A, Koutsioumpa M, O'Brien NA, Vorvis C, Iliopoulos D, Slamon DJ. A chemically-modified miR-21 inhibitor (ADM-21) as a novel potential therapy in bladder cancer. Journal of Clinical Oncology. 35: 335-335. DOI: 10.1200/Jco.2017.35.6_Suppl.335 |
0.421 |
|
| 2017 |
Hatziapostolou M, Koutsioumpa M, Polytarchou C, Mahurkar-Joshi S, Poultsides G, Dawson D, Iliopoulos D. AODTH-010 A mirna-epigenetic network in pancreatic cancer Gut. 66. DOI: 10.1136/Gutjnl-2017-314472.397 |
0.405 |
|
| 2017 |
Bakirtzi K, Iliopoulos D, Pothoulakis C. Substance P-Induced Colonic Epithelial Cell-Secreted Exosomes Exacerbate Experimental Colitis and Regulate Cell Proliferation and Migration via Exosomal MIR-21 Gastroenterology. 152: S103. DOI: 10.1016/S0016-5085(17)30684-4 |
0.36 |
|
| 2017 |
Mahurkar-Joshi S, Labus JS, Jacobs J, Videlock EJ, Lagishetty V, Iliopoulos D, Mayer EA, Chang L. Colonic Mucosal Microbiome is Associated with Mucosal Microrna Expression in Irritable Bowel Syndrome Gastroenterology. 152: S40-S41. DOI: 10.1016/S0016-5085(17)30499-7 |
0.318 |
|
| 2016 |
Padua DM, Mahurkar-Joshi S, Law IK, Polytarchou C, Vu JP, Pisegna JR, Shih DQ, Iliopoulos D, Pothoulakis C. A long noncoding RNA signature for ulcerative colitis identifies IFNG-AS1 as an enhancer of inflammation. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00212.2016. PMID 27492330 DOI: 10.1152/Ajpgi.00212.2016 |
0.356 |
|
| 2016 |
Palumbo T, Poultsides GA, Kouraklis G, Liakakos T, Drakaki A, Peros G, Hatziapostolou M, Iliopoulos D. A functional microRNA library screen reveals miR-410 as a novel anti-apoptotic regulator of cholangiocarcinoma. Bmc Cancer. 16: 353. PMID 27259577 DOI: 10.1186/S12885-016-2384-0 |
0.389 |
|
| 2016 |
Vorvis C, Hatziapostolou M, Mahurkar-Joshi S, Koutsioumpa M, Williams J, Donahue TR, Poultsides GA, Eibl G, Iliopoulos D. Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00035.2016. PMID 27151939 DOI: 10.1152/Ajpgi.00035.2016 |
0.441 |
|
| 2016 |
Bakirtzi K, Law IK, Xue X, Iliopoulos D, Shah YM, Pothoulakis C. Neurotensin Promotes the Development of Colitis and Intestinal Angiogenesis via Hif-1α-miR-210 Signaling. Journal of Immunology (Baltimore, Md. : 1950). PMID 27076683 DOI: 10.4049/Jimmunol.1501443 |
0.334 |
|
| 2016 |
Vorvis C, Koutsioumpa M, Iliopoulos D. Developments in miRNA gene signaling pathways in pancreatic cancer. Future Oncology (London, England). 12: 1135-50. PMID 26984178 DOI: 10.2217/Fon-2015-0050 |
0.33 |
|
| 2016 |
Koutsioumpa M, Hatziapostolou M, Polytarchou C, Oikonomopoulos A, Mahurkar-Joshi S, Huerta-Yepez S, Tirado-Rodriguez B, Karavias D, Kourea H, Poultsides GA, Dawson DW, Donahue TR, Iliopoulos D. Abstract 4528: Chromatin regulation by ING3 leads to tumor suppressive effects in pancreatic cancer through distinct signaling pathways Cancer Research. 76: 4528-4528. DOI: 10.1158/1538-7445.Am2016-4528 |
0.417 |
|
| 2016 |
Fang K, Law IKM, Sideri A, Huang V, Padua DM, Iliopoulos D, Pothoulakis C. Tu1839 miR-31-3p Is Involved in Substance P (SP)-Associated Inflammation in Human Colonic Epithelial Cells and Experimental Colitis Gastroenterology. 150: S957. DOI: 10.1016/S0016-5085(16)33233-4 |
0.338 |
|
| 2016 |
Mahurkar-Joshi S, Videlock EJ, Iliopoulos D, Mayer EA, Chang L. Tu1794 Functional Pathways Associated With Differential Colonic Mucosal Expression of microRNA and mRNA in Irritable Bowel Syndrome Gastroenterology. 150: S949. DOI: 10.1016/S0016-5085(16)33205-X |
0.323 |
|
| 2016 |
DRAKAKI A, O'BRIEN N, VORVIS C, ILIOPOULOS D, SLAMON D. MP88-11 THERAPEUTIC EFFECTS OF A MICRORNA-21 CHEMICAL INHIBITOR ON BLADDER CANCER PRECLINICAL MODELS Journal of Urology. 195. DOI: 10.1016/J.Juro.2016.02.2429 |
0.331 |
|
| 2015 |
Fang K, Sideri A, Man-Law IK, Bakirtzi K, Polytarchou C, Iliopoulos D, Pothoulakis C. Identification of a novel substance P (SP)-neurokinin-1 receptor (NK-1R) microRNA-221-5p inflammatory network in human colonic epithelial cells. Cellular and Molecular Gastroenterology and Hepatology. 1: 503-515. PMID 26645045 DOI: 10.1016/J.Jcmgh.2015.06.008 |
0.351 |
|
| 2015 |
Krasoudaki E, Banos A, Stagakis E, Loupasakis K, Drakos E, Sinatkas V, Zampoulaki A, Papagianni A, Iliopoulos D, Boumpas DT, Bertsias GK. Micro-RNA analysis of renal biopsies in human lupus nephritis demonstrates up-regulated miR-422a driving reduction of kallikrein-related peptidase 4. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. PMID 26546590 DOI: 10.1093/Ndt/Gfv374 |
0.339 |
|
| 2015 |
Rodriguez JA, Huerta-Yepez S, Law IK, Baay-Guzman GJ, Tirado-Rodriguez B, Hoffman JM, Iliopoulos D, Hommes DW, Verspaget HW, Chang L, Pothoulakis C, Baritaki S. Diminished expression of CRHR2 in human colon cancer promotes tumor growth and EMT via persistent IL-6/Stat3 signaling. Cellular and Molecular Gastroenterology and Hepatology. 1: 610-630. PMID 26495412 DOI: 10.1016/J.Jcmgh.2015.08.001 |
0.364 |
|
| 2015 |
Drakaki A, Hatziapostolou M, Polytarchou C, Vorvis C, Poultsides GA, Souglakos J, Georgoulias V, Iliopoulos D. Functional microRNA high throughput screening reveals miR-9 as a central regulator of liver oncogenesis by affecting the PPARA-CDH1 pathway. Bmc Cancer. 15: 542. PMID 26206264 DOI: 10.1186/S12885-015-1562-9 |
0.356 |
|
| 2015 |
Polytarchou C, Hommes DW, Palumbo T, Hatziapostolou M, Koutsioumpa M, Koukos G, van der Meulen-de Jong AE, Oikonomopoulos A, van Deen WK, Vorvis C, Serebrennikova OB, Birli E, Choi J, Chang L, Anton PA, ... ... Iliopoulos D, et al. MicroRNA214 is Associated with Progression of Ulcerative Colitis, and Inhibition Reduces Development of Colitis and Colitis-associated Cancer in Mice. Gastroenterology. PMID 26055138 DOI: 10.1053/J.Gastro.2015.05.057 |
0.365 |
|
| 2015 |
Koukos G, Polytarchou C, Kaplan JL, Oikonomopoulos A, Ziring D, Hommes DW, Wahed R, Kokkotou E, Pothoulakis C, Winter HS, Iliopoulos D. A microRNA signature in pediatric ulcerative colitis: deregulation of the miR-4284/CXCL5 pathway in the intestinal epithelium. Inflammatory Bowel Diseases. 21: 996-1005. PMID 25738378 DOI: 10.1097/Mib.0000000000000339 |
0.339 |
|
| 2015 |
Law IK, Bakirtzi K, Polytarchou C, Oikonomopoulos A, Hommes D, Iliopoulos D, Pothoulakis C. Neurotensin--regulated miR-133α is involved in proinflammatory signalling in human colonic epithelial cells and in experimental colitis. Gut. 64: 1095-104. PMID 25112884 DOI: 10.1136/Gutjnl-2014-307329 |
0.356 |
|
| 2015 |
Hatziapostolou M, Koutsioumpa M, Kottakis F, Iliopoulos D, Polytarchou C. Targeting colon cancer metabolism through a long noncoding RNA. Journal of Clinical Oncology. 33: 604-604. DOI: 10.1200/Jco.2015.33.3_Suppl.604 |
0.41 |
|
| 2015 |
Polytarchou C, Hommes DW, Palumbo T, Hatziapostolou M, Koukos G, van der Meulen-de Jong AE, Oikonomopoulos A, van Deen WK, Vorvis C, Koutsioumpa M, Birli E, Choi J, Chang L, Anton PA, Pothoulakis C, ... ... Iliopoulos D, et al. MicroRNA targeting for the therapy of colitis-associated colon cancer. Journal of Clinical Oncology. 33: 571-571. DOI: 10.1200/Jco.2015.33.3_Suppl.571 |
0.414 |
|
| 2015 |
Koutsioumpa M, Hatziapostolou M, Polytarchou C, Joshi S, Iliopoulos D. ING3 as a novel regulator of pancreatic cancer growth and aggressiveness. Journal of Clinical Oncology. 33: 304-304. DOI: 10.1200/Jco.2015.33.3_Suppl.304 |
0.422 |
|
| 2015 |
Drakaki A, Polytarchou C, O'Brien NA, Iliopoulos D, Slamon DJ. Role and therapeutic targeting of miR-21 in bladder cancer. Journal of Clinical Oncology. 33: e15542-e15542. DOI: 10.1200/Jco.2015.33.15_Suppl.E15542 |
0.383 |
|
| 2015 |
Hatziapostolou M, Koutsioumpa M, Kottakis F, Hommes DW, Verspaget HW, Iliopoulos D, Polytarchou C. Tu1996 Regulation of Colon Cancer Metabolism by a Long Non-Coding RNA Gastroenterology. 148: S-955. DOI: 10.1016/S0016-5085(15)33262-5 |
0.305 |
|
| 2015 |
Koutsioumpa M, Hatziapostolou M, Polytarchou C, Vorvi C, Joshi SM, Iliopoulos D. 550 A Novel Epigenetic Regulator of Pancreatic Cancer Growth Gastroenterology. 148: S-111. DOI: 10.1016/S0016-5085(15)30382-6 |
0.338 |
|
| 2015 |
Fang K, Law IKM, Sideri A, Koon HW, Iliopoulos D, Pothoulakis C. 154 Expression of Substance P (SP)-Regulated miR-31-3p Is Increased in Colitis and Modulates RhoA Expression in Human Colonic Epithelial Cells Gastroenterology. 148: S-41-S-42. DOI: 10.1016/S0016-5085(15)30143-8 |
0.369 |
|
| 2014 |
Bakirtzi K, West G, Fiocchi C, Law IK, Iliopoulos D, Pothoulakis C. The neurotensin-HIF-1α-VEGFα axis orchestrates hypoxia, colonic inflammation, and intestinal angiogenesis. The American Journal of Pathology. 184: 3405-14. PMID 25307345 DOI: 10.1016/J.Ajpath.2014.08.015 |
0.332 |
|
| 2014 |
Chen X, Iliopoulos D, Zhang Q, Tang Q, Greenblatt MB, Hatziapostolou M, Lim E, Tam WL, Ni M, Chen Y, Mai J, Shen H, Hu DZ, Adoro S, Hu B, et al. XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway. Nature. 508: 103-7. PMID 24670641 DOI: 10.1038/Nature13119 |
0.378 |
|
| 2014 |
Iliopoulos D. MicroRNA circuits regulate the cancer-inflammation link. Science Signaling. 7: pe8. PMID 24667374 DOI: 10.1126/Scisignal.2005053 |
0.427 |
|
| 2014 |
Sanidas I, Polytarchou C, Hatziapostolou M, Ezell SA, Kottakis F, Hu L, Guo A, Xie J, Comb MJ, Iliopoulos D, Tsichlis PN. Phosphoproteomics screen reveals akt isoform-specific signals linking RNA processing to lung cancer. Molecular Cell. 53: 577-90. PMID 24462114 DOI: 10.1016/J.Molcel.2013.12.018 |
0.329 |
|
| 2014 |
Sanidas I, Polytarchou C, Hatziapostolou M, Ezell SA, Kottakis F, Hu L, Guo A, Xie J, Comb MJ, Iliopoulos D, Tsichlis PN. Abstract 4777: A phosphoproteomics analysis reveals Akt isoform-specific signals that link RNA splicing to non-small cell lung cancer Cancer Research. 74: 4777-4777. DOI: 10.1158/1538-7445.Am2014-4777 |
0.371 |
|
| 2014 |
Bakirtzi K, Law IKM, Polytarchou C, Hommes DW, Iliopoulos D, Pothoulakis C. Tu1729 Neurotensin (NT) Through the Regulation of MicroRNA (miR)-210 Promotes the Development of Colitis and Intestinal Angiogenesis Gastroenterology. 146: S-828. DOI: 10.1016/S0016-5085(14)63005-5 |
0.344 |
|
| 2014 |
Rodriguez J, Iliopoulos D, Ypez Sh, Hoffman JM, Baay-Gusman GJ, Tirado-Rodriguez AB, Law IKM, Hommes DW, Verspaget HW, Chang L, Pothoulakis C, Baritaki S. Tu1670 Inhibition of Corticotropin-Releasing Hormone Receptor 2 (CRHR2) Expression in Colorectal Cancer Correlates With Tumor Growth and EMT In Vitro and In Vivo, Poor Patient Survival and Increased Risk for Distant Metastases Gastroenterology. 146: S-814. DOI: 10.1016/S0016-5085(14)62946-2 |
0.339 |
|
| 2013 |
Drakaki A, Iliopoulos D. MicroRNA-gene signaling pathways in pancreatic cancer. Biomedical Journal. 36: 200-8. PMID 24225187 DOI: 10.4103/2319-4170.119690 |
0.36 |
|
| 2013 |
Koukos G, Polytarchou C, Kaplan JL, Morley-Fletcher A, Gras-Miralles B, Kokkotou E, Baril-Dore M, Pothoulakis C, Winter HS, Iliopoulos D. MicroRNA-124 regulates STAT3 expression and is down-regulated in colon tissues of pediatric patients with ulcerative colitis. Gastroenterology. 145: 842-52.e2. PMID 23856509 DOI: 10.1053/J.Gastro.2013.07.001 |
0.368 |
|
| 2013 |
Hatziapostolou M, Polytarchou C, Iliopoulos D. miRNAs link metabolic reprogramming to oncogenesis. Trends in Endocrinology and Metabolism: Tem. 24: 361-73. PMID 23602813 DOI: 10.1016/J.Tem.2013.03.002 |
0.337 |
|
| 2013 |
Hirsch HA, Iliopoulos D, Struhl K. Metformin inhibits the inflammatory response associated with cellular transformation and cancer stem cell growth. Proceedings of the National Academy of Sciences of the United States of America. 110: 972-7. PMID 23277563 DOI: 10.1073/Pnas.1221055110 |
0.357 |
|
| 2013 |
Drakaki A, Hatziapostolou M, Iliopoulos D. Therapeutically targeting microRNAs in liver cancer. Current Pharmaceutical Design. 19: 1180-91. PMID 23092338 DOI: 10.2174/138161213804805658 |
0.35 |
|
| 2013 |
Palumbo T, Faucz FR, Azevedo M, Xekouki P, Iliopoulos D, Stratakis CA. Functional screen analysis reveals miR-26b and miR-128 as central regulators of pituitary somatomammotrophic tumor growth through activation of the PTEN-AKT pathway Oncogene. 32: 1651-1659. PMID 22614013 DOI: 10.1038/Onc.2012.190 |
0.376 |
|
| 2013 |
Drakaki A, Hatziapostolou M, Polytarchou C, Iliopoulos D. The role of microRNA-9 in hepatocellular oncogenesis. Journal of Clinical Oncology. 31: 168-168. DOI: 10.1200/Jco.2013.31.4_Suppl.168 |
0.381 |
|
| 2013 |
Baritaki S, Rodriguez J, Iliopoulos D, Pothoulakis C. Abstract 1484: Effects of UCN2 and its receptor CRHR2 in colorectal cancer growth and metastasis. Cancer Research. 73: 1484-1484. DOI: 10.1158/1538-7445.Am2013-1484 |
0.371 |
|
| 2013 |
Krasoudaki E, Stagakis E, Loupasakis K, Papagianni A, Alexopoulos E, Bertsias G, Iliopoulos D, Boumpas D. SAT0006 Microrna analysis of human lupus nephritis: Evidence for modulation of kallikrein 4 by MIR-422A Annals of the Rheumatic Diseases. 71: 472.3-473. DOI: 10.1136/Annrheumdis-2012-Eular.2954 |
0.358 |
|
| 2013 |
Bakirtzi K, Polytarchou C, Hatziapostolou M, Iliopoulos D, Pothoulakis C. Sa1731 Neurotensin-HIF-1α-MicroRNA 210 Axis Orchestrates Hypoxia, Colonic Inflammation and Intestinal Angiogenesis Gastroenterology. 144: S-294. DOI: 10.1016/S0016-5085(13)61043-4 |
0.347 |
|
| 2013 |
Law IKM, Bakirtzi K, Polytarchou C, Bunnett NW, Iliopoulos D, Pothoulakis C. 934 Neurotensin-Induced Tumor Formation Is Regulated by Neurotensin Receptor 1 (NTR1)/MicroRNA-133a-Associated NTR1 Recycling Involving the Negative Regulator Zinc Finger E-Box-Binding Homeobox 1 (ZEB1) Gastroenterology. 144: S-167. DOI: 10.1016/S0016-5085(13)60598-3 |
0.303 |
|
| 2012 |
Polytarchou C, Iliopoulos D, Struhl K. An integrated transcriptional regulatory circuit that reinforces the breast cancer stem cell state. Proceedings of the National Academy of Sciences of the United States of America. 109: 14470-5. PMID 22908280 DOI: 10.1073/Pnas.1212811109 |
0.392 |
|
| 2012 |
Lee JJ, Drakaki A, Iliopoulos D, Struhl K. MiR-27b targets PPARγ to inhibit growth, tumor progression and the inflammatory response in neuroblastoma cells. Oncogene. 31: 3818-25. PMID 22120719 DOI: 10.1038/Onc.2011.543 |
0.419 |
|
| 2012 |
Papadimitriou E, Vasilaki E, Vorvis C, Iliopoulos D, Moustakas A, Kardassis D, Stournaras C. Differential regulation of the two RhoA-specific GEF isoforms Net1/Net1A by TGF-β and miR-24: role in epithelial-to-mesenchymal transition. Oncogene. 31: 2862-75. PMID 21986943 DOI: 10.1038/Onc.2011.457 |
0.304 |
|
| 2012 |
Vorvis C, Poultsides GA, Norton JA, Iliopoulos D. Abstract 5335: Identification and molecular characterization of pancreatic tumor-initiating cells Cancer Research. 72: 5335-5335. DOI: 10.1158/1538-7445.Am2012-5335 |
0.368 |
|
| 2012 |
Koukos G, Polytarchou C, Hatziapostolou M, Drakaki A, Pothoulakis C, Iliopoulos D. Sa1807 Adiponectin Inflammatory and Metabolic Networks Regulate the Growth of Colon Tumor-Initiating Cells Gastroenterology. 142: S-330-S-331. DOI: 10.1016/S0016-5085(12)61244-X |
0.317 |
|
| 2012 |
Hatziapostolou M, Polytarchou C, Drakaki A, Poultsides GA, Iliopoulos D. Sa1790 MiR-124 Systemic Delivery as a Novel Therapeutic Approach for Hepatocellular Cancer Gastroenterology. 142: S-326. DOI: 10.1016/S0016-5085(12)61227-X |
0.337 |
|
| 2012 |
Palumbo T, Poultsides GA, Vorvis C, Iliopoulos D. 1049 MicroRNA Library Screen Reveals Mir-410 as Anti-Apoptotic Factor in Cholangiocarcinomas Gastroenterology. 142: S-184-S-185. DOI: 10.1016/S0016-5085(12)60692-1 |
0.309 |
|
| 2012 |
Polytarchou C, Palumbo T, Hatziapostolou M, Pothoulakis C, Iliopoulos D. 1048 Mir-214 as a Therapeutic Target in Ulcerative Colitis (UC)-Associated Colon Cancer Gastroenterology. 142: S-184. DOI: 10.1016/S0016-5085(12)60691-X |
0.372 |
|
| 2012 |
Hatziapostolou M, Pothoulakis C, Iliopoulos D. 207 A MicroRNA-Epigenetic Circuit Regulates Colon Cancer Stem Cells Gastroenterology. 142: S-51. DOI: 10.1016/S0016-5085(12)60196-6 |
0.356 |
|
| 2012 |
Vorvis C, Poultsides GA, Norton JA, Hatziapostolou M, Iliopoulos D. 206 Identification and Whole Transcriptome Characterization of Pancreatic Cancer Stem Cells Gastroenterology. 142: S-50-S-51. DOI: 10.1016/S0016-5085(12)60195-4 |
0.306 |
|
| 2011 |
Polytarchou C, Bugni JM, Dry S, Pothoulakis C, Iliopoulos D. Effects of a neurokinin-1 receptor (NK-1R) antagonist on colon cancer through suppression of colon tumor-initiating cells. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 3614. PMID 28020845 DOI: 10.1200/Jco.2011.29.15_Suppl.3614 |
0.373 |
|
| 2011 |
Hatziapostolou M, Polytarchou C, Aggelidou E, Drakaki A, Poultsides GA, Jaeger SA, Ogata H, Karin M, Struhl K, Hadzopoulou-Cladaras M, Iliopoulos D. An HNF4α-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesis. Cell. 147: 1233-47. PMID 22153071 DOI: 10.1016/J.Cell.2013.02.013 |
0.36 |
|
| 2011 |
Piskounova E, Polytarchou C, Thornton JE, LaPierre RJ, Pothoulakis C, Hagan JP, Iliopoulos D, Gregory RI. Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms. Cell. 147: 1066-79. PMID 22118463 DOI: 10.1016/J.Cell.2011.10.039 |
0.404 |
|
| 2011 |
Bakirtzi K, Hatziapostolou M, Karagiannides I, Polytarchou C, Jaeger S, Iliopoulos D, Pothoulakis C. Neurotensin signaling activates microRNAs-21 and -155 and Akt, promotes tumor growth in mice, and is increased in human colon tumors. Gastroenterology. 141: 1749-61.e1. PMID 21806946 DOI: 10.1053/J.Gastro.2011.07.038 |
0.432 |
|
| 2011 |
Iliopoulos D, Rotem A, Struhl K. Inhibition of miR-193a expression by Max and RXRα activates K-Ras and PLAU to mediate distinct aspects of cellular transformation. Cancer Research. 71: 5144-53. PMID 21670079 DOI: 10.1158/0008-5472.Can-11-0425 |
0.351 |
|
| 2011 |
Stagakis E, Bertsias G, Verginis P, Nakou M, Hatziapostolou M, Kritikos H, Iliopoulos D, Boumpas DT. Identification of novel microRNA signatures linked to human lupus disease activity and pathogenesis: miR-21 regulates aberrant T cell responses through regulation of PDCD4 expression. Annals of the Rheumatic Diseases. 70: 1496-506. PMID 21602271 DOI: 10.1136/Ard.2010.139857 |
0.353 |
|
| 2011 |
Polytarchou C, Iliopoulos D, Hatziapostolou M, Kottakis F, Maroulakou I, Struhl K, Tsichlis PN. Akt2 regulates all Akt isoforms and promotes resistance to hypoxia through induction of miR-21 upon oxygen deprivation. Cancer Research. 71: 4720-31. PMID 21555366 DOI: 10.1158/0008-5472.Can-11-0365 |
0.372 |
|
| 2011 |
Iliopoulos D, Kavousanaki M, Ioannou M, Boumpas D, Verginis P. The negative costimulatory molecule PD-1 modulates the balance between immunity and tolerance via miR-21. European Journal of Immunology. 41: 1754-63. PMID 21469086 DOI: 10.1002/Eji.201040646 |
0.328 |
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| 2011 |
Iliopoulos D, Hirsch HA, Struhl K. Metformin decreases the dose of chemotherapy for prolonging tumor remission in mouse xenografts involving multiple cancer cell types. Cancer Research. 71: 3196-201. PMID 21415163 DOI: 10.1158/0008-5472.Can-10-3471 |
0.345 |
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| 2011 |
Hatziapostolou M, Iliopoulos D. Epigenetic aberrations during oncogenesis. Cellular and Molecular Life Sciences : Cmls. 68: 1681-702. PMID 21249513 DOI: 10.1007/S00018-010-0624-Z |
0.357 |
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| 2011 |
Iliopoulos D, Hirsch HA, Wang G, Struhl K. Inducible formation of breast cancer stem cells and their dynamic equilibrium with non-stem cancer cells via IL6 secretion. Proceedings of the National Academy of Sciences of the United States of America. 108: 1397-402. PMID 21220315 DOI: 10.1073/Pnas.1018898108 |
0.347 |
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| 2011 |
Papanikolaou V, Iliopoulos D, Dimou I, Dubos S, Kappas C, Kitsiou-Tzeli S, Tsezou A. Survivin regulation by HER2 through NF-κB and c-myc in irradiated breast cancer cells. Journal of Cellular and Molecular Medicine. 15: 1542-50. PMID 20716114 DOI: 10.1111/J.1582-4934.2010.01149.X |
0.36 |
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| 2011 |
Chatziapostolou M, Iliopoulos D. Abstract 972: Epigenetic-microRNA networks in colon cancer stem cells Cancer Research. 71: 972-972. DOI: 10.1158/1538-7445.Am2011-972 |
0.432 |
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| 2011 |
Bakirtzi K, Iliopoulos D, Karagiannidis I, Bugni JM, Hatziapostolou M, Pothoulakis C. Neurotensin (NT) Receptor 1 (Ntr1)-MicroRNA Networks in Human Colon Epithelial Cells. Characterization of Novel Pathways Connecting Neurotensin and Tumor Growth Gastroenterology. 140: S-102-S-103. DOI: 10.1016/S0016-5085(11)60417-4 |
0.322 |
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| 2010 |
Levy C, Khaled M, Iliopoulos D, Janas MM, Schubert S, Pinner S, Chen PH, Li S, Fletcher AL, Yokoyama S, Scott KL, Garraway LA, Song JS, Granter SR, Turley SJ, et al. Intronic miR-211 assumes the tumor suppressive function of its host gene in melanoma. Molecular Cell. 40: 841-9. PMID 21109473 DOI: 10.1016/J.Molcel.2010.11.020 |
0.382 |
|
| 2010 |
Iliopoulos D, Lindahl-Allen M, Polytarchou C, Hirsch HA, Tsichlis PN, Struhl K. Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells. Molecular Cell. 39: 761-72. PMID 20832727 DOI: 10.1016/J.Molcel.2010.08.013 |
0.386 |
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| 2010 |
Iliopoulos D, Jaeger SA, Hirsch HA, Bulyk ML, Struhl K. STAT3 activation of miR-21 and miR-181b-1 via PTEN and CYLD are part of the epigenetic switch linking inflammation to cancer. Molecular Cell. 39: 493-506. PMID 20797623 DOI: 10.1016/J.Molcel.2010.07.023 |
0.379 |
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| 2010 |
Hirsch HA, Iliopoulos D, Joshi A, Zhang Y, Jaeger SA, Bulyk M, Tsichlis PN, Shirley Liu X, Struhl K. A transcriptional signature and common gene networks link cancer with lipid metabolism and diverse human diseases. Cancer Cell. 17: 348-61. PMID 20385360 DOI: 10.1016/J.Ccr.2010.01.022 |
0.375 |
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| 2010 |
Iliopoulos D, Drosatos K, Hiyama Y, Goldberg IJ, Zannis VI. MicroRNA-370 controls the expression of microRNA-122 and Cpt1alpha and affects lipid metabolism. Journal of Lipid Research. 51: 1513-23. PMID 20124555 DOI: 10.1194/Jlr.M004812 |
0.354 |
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| 2010 |
Bimpaki EI, Iliopoulos D, Moraitis A, Stratakis CA. MicroRNA signature in massive macronodular adrenocortical disease and implications for adrenocortical tumourigenesis. Clinical Endocrinology. 72: 744-51. PMID 19849700 DOI: 10.1111/J.1365-2265.2009.03725.X |
0.351 |
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| 2010 |
Stagakis E, Verginis P, Nakou M, Bertsias G, Krasoudaki E, Choustoulaki E, Kritikos H, Iliopoulos D, Boumpas DT. Micro RNA analysis reveals novel genes in human systemic lupus erythematosus: miR-21 affects PDCD4 expression and regulates aberrant T cell responses Annals of the Rheumatic Diseases. 69. DOI: 10.1136/Ard.2010.129619A |
0.32 |
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| 2009 |
Orfanidou T, Iliopoulos D, Malizos KN, Tsezou A. Involvement of SOX-9 and FGF-23 in RUNX-2 regulation in osteoarthritic chondrocytes. Journal of Cellular and Molecular Medicine. 13: 3186-94. PMID 20196777 DOI: 10.1111/J.1582-4934.2009.00678.X |
0.303 |
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| 2009 |
Iliopoulos D, Hirsch HA, Struhl K. An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell. 139: 693-706. PMID 19878981 DOI: 10.1016/J.Cell.2009.10.014 |
0.328 |
|
| 2009 |
Iliopoulos D, Polytarchou C, Hatziapostolou M, Kottakis F, Maroulakou IG, Struhl K, Tsichlis PN. MicroRNAs differentially regulated by Akt isoforms control EMT and stem cell renewal in cancer cells. Science Signaling. 2: ra62. PMID 19825827 DOI: 10.1126/Scisignal.2000356 |
0.405 |
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| 2009 |
Papanikolaou V, Iliopoulos D, Dimou I, Dubos S, Tsougos I, Theodorou K, Kitsiou-Tzeli S, Tsezou A. The involvement of HER2 and p53 status in the regulation of telomerase in irradiated breast cancer cells. International Journal of Oncology. 35: 1141-9. PMID 19787269 DOI: 10.3892/Ijo_00000430 |
0.372 |
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| 2009 |
Hirsch HA, Iliopoulos D, Tsichlis PN, Struhl K. Metformin selectively targets cancer stem cells, and acts together with chemotherapy to block tumor growth and prolong remission. Cancer Research. 69: 7507-11. PMID 19752085 DOI: 10.1158/0008-5472.Can-09-2994 |
0.351 |
|
| 2009 |
Drakaki A, Iliopoulos D. MicroRNA Gene Networks in Oncogenesis. Current Genomics. 10: 35-41. PMID 19721809 DOI: 10.2174/138920209787581299 |
0.411 |
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| 2009 |
Androulidaki A, Iliopoulos D, Arranz A, Doxaki C, Schworer S, Zacharioudaki V, Margioris AN, Tsichlis PN, Tsatsanis C. The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs. Immunity. 31: 220-31. PMID 19699171 DOI: 10.1016/J.Immuni.2009.06.024 |
0.331 |
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| 2009 |
Iliopoulos D, Oikonomou P, Messinis I, Tsezou A. Correlation of promoter hypermethylation in hTERT, DAPK and MGMT genes with cervical oncogenesis progression. Oncology Reports. 22: 199-204. PMID 19513524 DOI: 10.3892/Or_00000425 |
0.339 |
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| 2009 |
Iliopoulos D, Bimpaki EI, Nesterova M, Stratakis CA. MicroRNA signature of primary pigmented nodular adrenocortical disease: clinical correlations and regulation of Wnt signaling. Cancer Research. 69: 3278-82. PMID 19351815 DOI: 10.1158/0008-5472.Can-09-0155 |
0.41 |
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| 2008 |
Petrocca F, Visone R, Onelli MR, Shah MH, Nicoloso MS, de Martino I, Iliopoulos D, Pilozzi E, Liu CG, Negrini M, Cavazzini L, Volinia S, Alder H, Ruco LP, Baldassarre G, et al. E2F1-regulated microRNAs impair TGFbeta-dependent cell-cycle arrest and apoptosis in gastric cancer. Cancer Cell. 13: 272-86. PMID 18328430 DOI: 10.1016/J.Ccr.2008.02.013 |
0.388 |
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| 2007 |
McCorkell KA, Mancini R, Siprashvili Z, Barnoski BL, Iliopoulos D, Siracusa LD, Zanesi N, Croce CM, Fong LY, Druck T, Huebner K. Influence of a nonfragile FHIT transgene on murine tumor susceptibility. Cytogenetic and Genome Research. 118: 196-203. PMID 18000371 DOI: 10.1159/000108301 |
0.492 |
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| 2007 |
Guler G, Iliopoulos D, Guler N, Himmetoglu C, Hayran M, Huebner K. Wwox and Ap2gamma expression levels predict tamoxifen response. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 6115-21. PMID 17947476 DOI: 10.1158/1078-0432.Ccr-07-1282 |
0.523 |
|
| 2007 |
Qin HR, Iliopoulos D, Nakamura T, Costinean S, Volinia S, Druck T, Sun J, Okumura H, Huebner K. Wwox suppresses prostate cancer cell growth through modulation of ErbB2-mediated androgen receptor signaling. Molecular Cancer Research : McR. 5: 957-65. PMID 17704139 DOI: 10.1158/1541-7786.Mcr-07-0211 |
0.529 |
|
| 2007 |
Iliopoulos D, Fabbri M, Druck T, Qin HR, Han SY, Huebner K. Inhibition of breast cancer cell growth in vitro and in vivo: effect of restoration of Wwox expression. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 268-74. PMID 17200365 DOI: 10.1158/1078-0432.Ccr-06-2038 |
0.538 |
|
| 2007 |
Cantor JP, Iliopoulos D, Rao AS, Druck T, Semba S, Han SY, McCorkell KA, Lakshman TV, Collins JE, Wachsberger P, Friedberg JS, Huebner K. Epigenetic modulation of endogenous tumor suppressor expression in lung cancer xenografts suppresses tumorigenicity. International Journal of Cancer. Journal International Du Cancer. 120: 24-31. PMID 17019711 DOI: 10.1002/Ijc.22073 |
0.557 |
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| 2006 |
Petrocca F, Iliopoulos D, Qin HR, Nicoloso MS, Yendamuri S, Wojcik SE, Shimizu M, Di Leva G, Vecchione A, Trapasso F, Godwin AK, Negrini M, Calin GA, Croce CM. Alterations of the tumor suppressor gene ARLTS1 in ovarian cancer. Cancer Research. 66: 10287-91. PMID 17079447 DOI: 10.1158/0008-5472.Can-06-2289 |
0.408 |
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| 2006 |
Semba S, Han SY, Qin HR, McCorkell KA, Iliopoulos D, Pekarsky Y, Druck T, Trapasso F, Croce CM, Huebner K. Biological functions of mammalian Nit1, the counterpart of the invertebrate NitFhit Rosetta stone protein, a possible tumor suppressor. The Journal of Biological Chemistry. 281: 28244-53. PMID 16864578 DOI: 10.1074/Jbc.M603590200 |
0.543 |
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| 2006 |
Qin HR, Iliopoulos D, Semba S, Fabbri M, Druck T, Volinia S, Croce CM, Morrison CD, Klein RD, Huebner K. A role for the WWOX gene in prostate cancer. Cancer Research. 66: 6477-81. PMID 16818616 DOI: 10.1158/0008-5472.Can-06-0956 |
0.54 |
|
| 2006 |
Pichiorri F, Trapasso F, Palumbo T, Aqeilan RI, Drusco A, Blaser BW, Iliopoulos D, Caligiuri MA, Huebner K, Croce CM. Preclinical assessment of FHIT gene replacement therapy in human leukemia using a chimeric adenovirus, Ad5/F35. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 3494-501. PMID 16740775 DOI: 10.1158/1078-0432.Ccr-05-2581 |
0.491 |
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| 2006 |
Semba S, Trapasso F, Fabbri M, McCorkell KA, Volinia S, Druck T, Iliopoulos D, Pekarsky Y, Ishii H, Garrison PN, Barnes LD, Croce CM, Huebner K. Fhit modulation of the Akt-survivin pathway in lung cancer cells: Fhit-tyrosine 114 (Y114) is essential. Oncogene. 25: 2860-72. PMID 16407838 DOI: 10.1038/Sj.Onc.1209323 |
0.523 |
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| 2006 |
Iliopoulos D, Guler G, Han SY, Druck T, Ottey M, McCorkell KA, Huebner K. Roles of FHIT and WWOX fragile genes in cancer. Cancer Letters. 232: 27-36. PMID 16225988 DOI: 10.1016/J.Canlet.2005.06.048 |
0.536 |
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| 2005 |
Fabbri M, Iliopoulos D, Trapasso F, Aqeilan RI, Cimmino A, Zanesi N, Yendamuri S, Han SY, Amadori D, Huebner K, Croce CM. WWOX gene restoration prevents lung cancer growth in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 102: 15611-6. PMID 16223882 DOI: 10.1073/Pnas.0505485102 |
0.539 |
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| 2005 |
Guler G, Uner A, Guler N, Han SY, Iliopoulos D, McCue P, Huebner K. Concordant loss of fragile gene expression early in breast cancer development. Pathology International. 55: 471-8. PMID 15998374 DOI: 10.1111/J.1440-1827.2005.01855.X |
0.535 |
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| 2005 |
Guler G, Iliopoulos D, Han SY, Fong LY, Lubet RA, Grubbs CJ, Huebner K. Hypermethylation patterns in the Fhit regulatory region are tissue specific. Molecular Carcinogenesis. 43: 175-81. PMID 15937960 DOI: 10.1002/Mc.20100 |
0.528 |
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| 2005 |
Iliopoulos D, Guler G, Han SY, Johnston D, Druck T, McCorkell KA, Palazzo J, McCue PA, Baffa R, Huebner K. Fragile genes as biomarkers: epigenetic control of WWOX and FHIT in lung, breast and bladder cancer. Oncogene. 24: 1625-33. PMID 15674328 DOI: 10.1038/Sj.Onc.1208398 |
0.526 |
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| 2004 |
Guler G, Uner A, Guler N, Han SY, Iliopoulos D, Hauck WW, McCue P, Huebner K. The fragile genes FHIT and WWOX are inactivated coordinately in invasive breast carcinoma. Cancer. 100: 1605-14. PMID 15073846 DOI: 10.1002/Cncr.20137 |
0.448 |
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| 2004 |
Han SY, Iliopoulos D, Druck T, Guler G, Grubbs CJ, Pereira M, Zhang Z, You M, Lubet RA, Fong LY, Huebner K. CpG methylation in the Fhit regulatory region: relation to Fhit expression in murine tumors. Oncogene. 23: 3990-8. PMID 15007387 DOI: 10.1038/Sj.Onc.1207526 |
0.476 |
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