Scott Kirk Napper - Publications

Affiliations: 
Biochemistry University of Saskatchewan, Saskatoon, SK, Canada 
Area:
Biochemistry
Website:
http://vido.org/team/project-leaders/scott-napper

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Facciuolo A, Lee AH, Gonzalez Cano P, Townsend HGG, Falsafi R, Gerdts V, Potter A, Napper S, Hancock REW, Mutharia LM, Griebel PJ. Regional Dichotomy in Enteric Mucosal Immune Responses to a Persistent ssp. Infection. Frontiers in Immunology. 11: 1020. PMID 32547548 DOI: 10.3389/Fimmu.2020.01020  0.32
2020 Facciuolo A, Denomy C, Lipsit S, Kusalik A, Napper S. From Beef to Bees: High-Throughput Kinome Analysis to Understand Host Responses of Livestock Species to Infectious Diseases and Industry-Associated Stress. Frontiers in Immunology. 11: 765. PMID 32499776 DOI: 10.3389/Fimmu.2020.00765  0.339
2020 Robertson AJ, Scruten E, Mostajeran M, Robertson T, Denomy C, Hogan D, Roesler A, Rutherford C, Kusalik A, Griebel P, Napper S. Kinome Analysis of Honeybee (Apis mellifera L.) Dark-Eyed Pupae Identifies Biomarkers and Mechanisms of Tolerance to Varroa Mite Infestation. Scientific Reports. 10: 2117. PMID 32034205 DOI: 10.1038/S41598-020-58927-2  0.348
2019 Miah S, Banks CAS, Ogunbolude Y, Bagu ET, Berg JM, Saraf A, Tettey TT, Hattem G, Dayebgadoh G, Kempf CG, Sardiu M, Napper S, Florens L, Lukong KE, Washburn MP. BRK phosphorylates SMAD4 for proteasomal degradation and inhibits tumor suppressor FRK to control SNAIL, SLUG, and metastatic potential. Science Advances. 5: eaaw3113. PMID 31681835 DOI: 10.1126/Sciadv.Aaw3113  0.334
2019 Prabaharan CB, Yang AB, Chidambaram D, Rajamanickam K, Napper S, Sakharkar MK. Ibrutinib as a potential therapeutic option for HER2 overexpressing breast cancer - the role of STAT3 and p21. Investigational New Drugs. PMID 31375978 DOI: 10.1007/S10637-019-00837-W  0.32
2019 Zhao B, Marciniuk K, Gibbs E, Yousefi M, Napper S, Cashman NR. Therapeutic vaccines for amyotrophic lateral sclerosis directed against disease specific epitopes of superoxide dismutase 1. Vaccine. PMID 31324499 DOI: 10.1016/J.Vaccine.2019.07.044  0.316
2018 McDonald M, Trost B, Napper S. Conservation of kinase-phosphorylation site pairings: Evidence for an evolutionarily dynamic phosphoproteome. Plos One. 13: e0202036. PMID 30106995 DOI: 10.1371/Journal.Pone.0202036  0.363
2018 Goel RK, Paczkowska M, Reimand J, Napper S, Lukong KE. Phosphoproteomics analysis identifies novel candidate substrates of the non-receptor tyrosine kinase, SRMS. Molecular & Cellular Proteomics : McP. PMID 29496907 DOI: 10.1074/Mcp.Ra118.000643  0.397
2017 Ogunbolude Y, Dai C, Bagu ET, Goel RK, Miah S, MacAusland-Berg J, Ng CY, Chibbar R, Napper S, Raptis L, Vizeacoumar F, Vizeacoumar F, Bonham K, Lukong KE. FRK inhibits breast cancer cell migration and invasion by suppressing epithelial-mesenchymal transition. Oncotarget. 8: 113034-113065. PMID 29348886 DOI: 10.18632/Oncotarget.22958  0.308
2017 Cano PG, Gamage LNA, Marciniuk K, Hayes C, Napper S, Hayes S, Griebel PJ. Lambda display phage as a mucosal vaccine delivery vehicle for peptide antigens. Vaccine. PMID 29153779 DOI: 10.1016/J.Vaccine.2017.11.010  0.323
2017 Baharani A, Trost B, Kusalik A, Napper S. Technological advances for interrogating the human kinome. Biochemical Society Transactions. 45: 65-77. PMID 28202660 DOI: 10.1042/Bst20160163  0.344
2017 Wu RY, Abdullah M, Määttänen P, Pilar AV, Scruten E, Johnson-Henry KC, Napper S, O'Brien C, Jones NL, Sherman PM. Protein kinase C δ signaling is required for dietary prebiotic-induced strengthening of intestinal epithelial barrier function. Scientific Reports. 7: 40820. PMID 28098206 DOI: 10.1038/Srep40820  0.344
2016 Van Wyk B, Snider M, Scruten E, van Drunen Littel-van den Hurk S, Napper S. Induction of functional interferon alpha and gamma responses during acute infection of cattle with non-cytopathic bovine viral diarrhea virus. Veterinary Microbiology. 195: 104-114. PMID 27771055 DOI: 10.1016/J.Vetmic.2016.09.015  0.345
2016 Chen Y, Stookey J, Arsenault R, Scruten E, Griebel P, Napper S. Investigation of the physiological, behavioral, and biochemical responses of cattle to restraint stress. Journal of Animal Science. 94: 3240-3254. PMID 27695781 DOI: 10.2527/Jas.2016-0549  0.52
2016 Facciuolo A, Gonzalez-Cano P, Napper S, Griebel PJ, Mutharia LM. Marked Differences in Mucosal Immune Responses Induced in Ileal versus Jejunal Peyer's Patches to Mycobacterium avium subsp. paratuberculosis Secreted Proteins following Targeted Enteric Infection in Young Calves. Plos One. 11: e0158747. PMID 27387969 DOI: 10.1371/Journal.Pone.0158747  0.342
2016 Trost B, Maleki F, Kusalik A, Napper S. DAPPLE 2: a tool for the homology-based prediction of post-translational modification sites. Journal of Proteome Research. PMID 27367363 DOI: 10.1021/Acs.Jproteome.6B00304  0.304
2016 Marciniuk K, Taschuk R, Napper S. Methods and Protocols for Developing Prion Vaccines. Methods in Molecular Biology (Clifton, N.J.). 1403: 657-80. PMID 27076159 DOI: 10.1007/978-1-4939-3387-7_37  0.334
2016 Trost B, Kusalik A, Napper S. Computational Analysis of the Predicted Evolutionary Conservation of Human Phosphorylation Sites. Plos One. 11: e0152809. PMID 27046079 DOI: 10.1371/Journal.Pone.0152809  0.354
2015 Chen Y, Arsenault R, Napper S, Griebel P. Models and Methods to Investigate Acute Stress Responses in Cattle. Animals : An Open Access Journal From Mdpi. 5: 1268-1295. PMID 26633525 DOI: 10.3390/Ani5040411  0.523
2015 Napper S, Dadgar S, Arsenault RJ, Trost B, Scruten E, Kusalik A, Shand P. Induction of tissue- and stressor-specific kinomic responses in chickens exposed to hot and cold stresses. Poultry Science. 94: 1333-45. PMID 25838314 DOI: 10.3382/Ps/Pev046  0.558
2015 Falcinelli S, Gowen BB, Trost B, Napper S, Kusalik A, Johnson RF, Safronetz D, Prescott J, Wahl-Jensen V, Jahrling PB, Kindrachuk J. Characterization of the host response to pichinde virus infection in the Syrian golden hamster by species-specific kinome analysis. Molecular & Cellular Proteomics : McP. 14: 646-57. PMID 25573744 DOI: 10.1074/Mcp.M114.045443  0.383
2015 Trost B, Napper S, Kusalik A. Case study: using sequence homology to identify putative phosphorylation sites in an evolutionarily distant species (honeybee). Briefings in Bioinformatics. 16: 820-9. PMID 25380664 DOI: 10.1093/Bib/Bbu040  0.323
2015 Arsenault R, Trost B, Kusalik A, Napper S. Development of Species-and Process-Specific Peptide Kinome Arrays with Priority Application to Investigations of Infectious Disease Kinomics: Approaches and Applications. 211-232. DOI: 10.1002/9783527683031.ch9  0.566
2014 Daigle J, Van Wyk B, Trost B, Scruten E, Arsenault R, Kusalik A, Griebel PJ, Napper S. Peptide Arrays for Kinome Analysis of Livestock Species. Frontiers in Veterinary Science. 1: 4. PMID 26664912 DOI: 10.3389/Fvets.2014.00004  0.601
2014 Kindrachuk J, Wahl-Jensen V, Safronetz D, Trost B, Hoenen T, Arsenault R, Feldmann F, Traynor D, Postnikova E, Kusalik A, Napper S, Blaney JE, Feldmann H, Jahrling PB. Ebola virus modulates transforming growth factor β signaling and cellular markers of mesenchyme-like transition in hepatocytes. Journal of Virology. 88: 9877-92. PMID 24942569 DOI: 10.1128/Jvi.01410-14  0.554
2014 Robertson AJ, Trost B, Scruten E, Robertson T, Mostajeran M, Connor W, Kusalik A, Griebel P, Napper S. Identification of developmentally-specific kinotypes and mechanisms of Varroa mite resistance through whole-organism, kinome analysis of honeybee. Frontiers in Genetics. 5: 139. PMID 24904639 DOI: 10.3389/Fgene.2014.00139  0.385
2014 Arsenault RJ, Maattanen P, Daigle J, Potter A, Griebel P, Napper S. From mouth to macrophage: mechanisms of innate immune subversion by Mycobacterium avium subsp. paratuberculosis. Veterinary Research. 45: 54. PMID 24885748 DOI: 10.1186/1297-9716-45-54  0.547
2014 Choi KY, Napper S, Mookherjee N. Human cathelicidin LL-37 and its derivative IG-19 regulate interleukin-32-induced inflammation. Immunology. 143: 68-80. PMID 24666281 DOI: 10.1111/Imm.12291  0.316
2014 Taschuk R, Marciniuk K, Määttänen P, Madampage C, Hedlin P, Potter A, Lee J, Cashman NR, Griebel PJ, Napper S. Safety, specificity and immunogenicity of a PrP(Sc)-specific prion vaccine based on the YYR disease specific epitope. Prion. 8: 51-9. PMID 24509522 DOI: 10.4161/Pri.27962  0.309
2014 Marciniuk K, Määttänen P, Taschuk R, Airey TD, Potter A, Cashman NR, Griebel P, Napper S. Development of a multivalent, PrP(Sc)-specific prion vaccine through rational optimization of three disease-specific epitopes. Vaccine. 32: 1988-97. PMID 24486363 DOI: 10.1016/J.Vaccine.2014.01.027  0.303
2014 Mulongo M, Prysliak T, Scruten E, Napper S, Perez-Casal J. In vitro infection of bovine monocytes with Mycoplasma bovis delays apoptosis and suppresses production of gamma interferon and tumor necrosis factor alpha but not interleukin-10. Infection and Immunity. 82: 62-71. PMID 24126524 DOI: 10.1128/Iai.00961-13  0.318
2013 Madampage CA, Marciniuk K, Määttänen P, Cashman NR, Potter A, Lee JS, Napper S. Nanopore analysis reveals differences in structural stability of ovine PrP(C) proteins corresponding to scrapie susceptible (VRQ) and resistance (ARR) genotypes. Prion. 7: 511-9. PMID 24401607 DOI: 10.4161/Pri.27502  0.313
2013 Trost B, Kindrachuk J, Määttänen P, Napper S, Kusalik A. PIIKA 2: an expanded, web-based platform for analysis of kinome microarray data. Plos One. 8: e80837. PMID 24312246 DOI: 10.1371/Journal.Pone.0080837  0.303
2013 Madampage CA, Määttänen P, Marciniuk K, Brownlie R, Andrievskaia O, Potter A, Cashman NR, Lee JS, Napper S. Binding of bovine T194A PrP(C) by PrP(Sc)-specific antibodies: potential implications for immunotherapy of familial prion diseases. Prion. 7: 301-11. PMID 23787697 DOI: 10.4161/Pri.25148  0.316
2013 Arsenault RJ, Napper S, Kogut MH. Salmonella enterica Typhimurium infection causes metabolic changes in chicken muscle involving AMPK, fatty acid and insulin/mTOR signaling. Veterinary Research. 44: 35. PMID 23682635 DOI: 10.1186/1297-9716-44-35  0.56
2013 Trost B, Arsenault R, Griebel P, Napper S, Kusalik A. DAPPLE: a pipeline for the homology-based prediction of phosphorylation sites. Bioinformatics (Oxford, England). 29: 1693-5. PMID 23658419 DOI: 10.1093/Bioinformatics/Btt265  0.534
2013 Charavaryamath C, Gonzalez-Cano P, Fries P, Gomis S, Doig K, Scruten E, Potter A, Napper S, Griebel PJ. Host responses to persistent Mycobacterium avium subspecies paratuberculosis infection in surgically isolated bovine ileal segments. Clinical and Vaccine Immunology : Cvi. 20: 156-65. PMID 23221000 DOI: 10.1128/Cvi.00496-12  0.303
2013 Arsenault RJ, Li Y, Maattanen P, Scruten E, Doig K, Potter A, Griebel P, Kusalik A, Napper S. Altered Toll-like receptor 9 signaling in Mycobacterium avium subsp. paratuberculosis-infected bovine monocytes reveals potential therapeutic targets. Infection and Immunity. 81: 226-37. PMID 23115040 DOI: 10.1128/Iai.00785-12  0.516
2012 Arsenault RJ, Li Y, Potter A, Griebel PJ, Kusalik A, Napper S. Induction of ligand-specific PrP (C) signaling in human neuronal cells. Prion. 6: 477-88. PMID 22918447 DOI: 10.4161/Pri.21914  0.583
2012 Arsenault RJ, Li Y, Bell K, Doig K, Potter A, Griebel PJ, Kusalik A, Napper S. Mycobacterium avium subsp. paratuberculosis inhibits gamma interferon-induced signaling in bovine monocytes: insights into the cellular mechanisms of Johne's disease. Infection and Immunity. 80: 3039-48. PMID 22689821 DOI: 10.1128/Iai.00406-12  0.539
2012 Li Y, Arsenault RJ, Trost B, Slind J, Griebel PJ, Napper S, Kusalik A. A systematic approach for analysis of peptide array kinome data. Science Signaling. 5: pl2. PMID 22510468 DOI: 10.1126/Scisignal.2002429  0.544
2012 Kindrachuk J, Arsenault R, Kusalik A, Kindrachuk KN, Trost B, Napper S, Jahrling PB, Blaney JE. Systems kinomics demonstrates Congo Basin monkeypox virus infection selectively modulates host cell signaling responses as compared to West African monkeypox virus. Molecular & Cellular Proteomics : McP. 11: M111.015701. PMID 22205724 DOI: 10.1074/Mcp.M111.015701  0.552
2011 Maddigan A, Truitt L, Arsenault R, Freywald T, Allonby O, Dean J, Narendran A, Xiang J, Weng A, Napper S, Freywald A. EphB receptors trigger Akt activation and suppress Fas receptor-induced apoptosis in malignant T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 187: 5983-94. PMID 22039307 DOI: 10.4049/Jimmunol.1003482  0.474
2011 Arsenault R, Griebel P, Napper S. Peptide arrays for kinome analysis: new opportunities and remaining challenges. Proteomics. 11: 4595-609. PMID 22002874 DOI: 10.1002/Pmic.201100296  0.61
2011 Lynn MA, Kindrachuk J, Marr AK, Jenssen H, Panté N, Elliott MR, Napper S, Hancock RE, McMaster WR. Effect of BMAP-28 antimicrobial peptides on Leishmania major promastigote and amastigote growth: role of leishmanolysin in parasite survival. Plos Neglected Tropical Diseases. 5: e1141. PMID 21655347 DOI: 10.1371/Journal.Pntd.0001141  0.312
2011 Turner-Brannen E, Choi KY, Arsenault R, El-Gabalawy H, Napper S, Mookherjee N. Inflammatory cytokines IL-32 and IL-17 have common signaling intermediates despite differential dependence on TNF-receptor 1. Journal of Immunology (Baltimore, Md. : 1950). 186: 7127-35. PMID 21602493 DOI: 10.4049/Jimmunol.1002306  0.458
2011 Van den Broeke A, Arsenault R, Rosewick N, Cleuter Y, Martiat P, Burny A, Napper S, Griebel P. Kinome profiling of BLV-induced ovine leukemia: an approach for identifying altered signaling pathways associated with oncogenesis Retrovirology. 8. DOI: 10.1186/1742-4690-8-S1-A16  0.586
2011 Broeke AVd, Arsenault R, Cleuter Y, Dehouck C, Martiat P, Burny A, Napper S, Griebel P. 227 Kinome Profiling of Bovine Leukemia Virus-induced Ovine Leukemia: An Approach for Identifying Altered Signaling Pathways and Drugable Targets in Cancer Jaids Journal of Acquired Immune Deficiency Syndromes. 56: 98. DOI: 10.1097/01.Qai.0000397409.60275.47  0.54
2010 Li L, Napper S, Cashman NR. Immunotherapy for prion diseases: opportunities and obstacles. Immunotherapy. 2: 269-82. PMID 20635933 DOI: 10.2217/Imt.10.3  0.326
2010 Booth JS, Arsenault R, Napper S, Griebel PJ, Potter AA, Babiuk LA, Mutwiri GK. TLR9 signaling failure renders Peyer's patch regulatory B cells unresponsive to stimulation with CpG oligodeoxynucleotides. Journal of Innate Immunity. 2: 483-94. PMID 20551621 DOI: 10.1159/000316574  0.504
2010 Scruten E, Kovacs-Nolan J, Griebel PJ, Latimer L, Kindrachuk J, Potter A, Babiuk LA, Littel-van den Hurk Sv, Napper S. Retro-inversion enhances the adjuvant and CpG co-adjuvant activity of host defence peptide Bac2A. Vaccine. 28: 2945-56. PMID 20193790 DOI: 10.1016/J.Vaccine.2010.02.015  0.319
2009 Arsenault RJ, Jalal S, Babiuk LA, Potter A, Griebel PJ, Napper S. Kinome analysis of Toll-like receptor signaling in bovine monocytes. Journal of Receptor and Signal Transduction Research. 29: 299-311. PMID 19899953 DOI: 10.3109/10799890903295127  0.561
2009 Jalal S, Arsenault R, Potter AA, Babiuk LA, Griebel PJ, Napper S. Genome to kinome: species-specific peptide arrays for kinome analysis. Science Signaling. 2: pl1. PMID 19155530 DOI: 10.1126/Scisignal.254Pl1  0.53
2008 Napper S, Prasad L, Delbaere LT. Structural investigation of a phosphorylation-catalyzed, isoaspartate-free, protein succinimide: crystallographic structure of post-succinimide His15Asp histidine-containing protein. Biochemistry. 47: 9486-96. PMID 18702519 DOI: 10.1021/Bi800847A  0.615
2008 Kindrachuk J, Potter J, Wilson HL, Griebel P, Babiuk LA, Napper S. Activation and regulation of toll-like receptor 9: CpGs and beyond. Mini Reviews in Medicinal Chemistry. 8: 590-600. PMID 18537714 DOI: 10.2174/138955708784534481  0.317
2007 Kindrachuk J, Paur N, Reiman C, Scruten E, Napper S. The PhoQ-activating potential of antimicrobial peptides contributes to antimicrobial efficacy and is predictive of the induction of bacterial resistance. Antimicrobial Agents and Chemotherapy. 51: 4374-81. PMID 17938183 DOI: 10.1128/Aac.00854-07  0.33
2006 Wilson HL, Dar A, Napper SK, Marianela Lopez A, Babiuk LA, Mutwiri GK. Immune mechanisms and therapeutic potential of CpG oligodeoxynucleotides. International Reviews of Immunology. 25: 183-213. PMID 16818371 DOI: 10.1080/08830180600785868  0.33
2006 Sampathkumar B, Napper S, Carrillo CD, Willson P, Taboada E, Nash JH, Potter AA, Babiuk LA, Allan BJ. Transcriptional and translational expression patterns associated with immobilized growth of Campylobacter jejuni. Microbiology (Reading, England). 152: 567-77. PMID 16436444 DOI: 10.1099/Mic.0.28405-0  0.303
2003 Napper S, Kindrachuk J, Olson DJ, Ambrose SJ, Dereniwsky C, Ross AR. Selective extraction and characterization of a histidine-phosphorylated peptide using immobilized copper(II) ion affinity chromatography and matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Analytical Chemistry. 75: 1741-7. PMID 12705611 DOI: 10.1021/Ac026340F  0.335
2003 Napper S, Wolanin PM, Webre DJ, Kindrachuk J, Waygood B, Stock JB. Intramolecular rearrangements as a consequence of the dephosphorylation of phosphoaspartate residues in proteins. Febs Letters. 538: 77-80. PMID 12633856 DOI: 10.1016/S0014-5793(03)00132-7  0.336
2002 Athmer L, Kindrachuk J, Georges F, Napper S. The influence of protein structure on the products emerging from succinimide hydrolysis. The Journal of Biological Chemistry. 277: 30502-7. PMID 12068021 DOI: 10.1074/Jbc.M205314200  0.319
2001 Napper S, Brokx SJ, Pally E, Kindrachuk J, Delbaere LT, Waygood EB. Substitution of aspartate and glutamate for active center histidines in the Escherichia coli phosphoenolpyruvate:sugar phosphotransferase system maintain phosphotransfer potential. The Journal of Biological Chemistry. 276: 41588-93. PMID 11551914 DOI: 10.1074/Jbc.M104139200  0.603
1999 Brokx SJ, Napper S, Wong G, Mirza A, Georges F, Delbaere LT, Waygood EB. Identification of the Escherichia coli enzyme I binding site in histidine-containing protein, HPr, by the effects of mutagenesis. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 77: 507-13. PMID 10668628 DOI: 10.1139/O99-063  0.584
1999 Napper S, Delbaere LT, Waygood EB. The aspartyl replacement of the active site histidine in histidine-containing protein, HPr, of the Escherichia coli Phosphoenolpyruvate:Sugar phosphotransferase system can accept and donate a phosphoryl group. Spontaneous dephosphorylation of acyl-phosphate autocatalyzes an internal cyclization. The Journal of Biological Chemistry. 274: 21776-82. PMID 10419492 DOI: 10.1074/Jbc.274.31.21776  0.617
1997 Stuart AL, Kumar SV, Gupta SV, Zoghaib WM, Napper S, Brown KC, Mannala S, Delbaere LT. Relationship Between Conformation and Antiviral Activity -IV. 5-Ethyl-2′-Deoxyurldine and 5-Ethyl-2′-Deoxycytidine+ Nucleosides and Nucleotides. 16: 2219-2231. DOI: 10.1080/07328319708002568  0.576
1996 Napper S, Anderson JW, Georges F, Quail JW, Delbaere LT, Waygood EB. Mutation of serine-46 to aspartate in the histidine-containing protein of Escherichia coli mimics the inactivation by phosphorylation of serine-46 in HPrs from gram-positive bacteria. Biochemistry. 35: 11260-7. PMID 8784179 DOI: 10.1021/Bi9603480  0.618
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