Heiko Heerklotz - Publications

Affiliations: 
Pharmaceutical Sciences University of Toronto, Toronto, ON, Canada 
Area:
Pharmacy, Biochemistry

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Year Citation  Score
2024 Eckhardt D, Semeraro EF, Steigenberger J, Schnur J, Kalie L, Massing U, Pabst G, Heerklotz H. Eutectic Resolves Lysolipid Paradox in Thermoresponsive Liposomes. Molecular Pharmaceutics. PMID 38381374 DOI: 10.1021/acs.molpharmaceut.3c01094  0.351
2023 Hua L, Kaiser M, Carabadjac I, Meister A, Hause G, Heerklotz H. Vesicle budding caused by lysolipid-induced asymmetry stress. Biophysical Journal. 122: 4011-4022. PMID 37649254 DOI: 10.1016/j.bpj.2023.08.023  0.385
2023 Krompers M, Heerklotz H. A Guide to Your Desired Lipid-Asymmetric Vesicles. Membranes. 13. PMID 36984654 DOI: 10.3390/membranes13030267  0.447
2023 Koehler JK, Gedda L, Wurster L, Schnur J, Edwards K, Heerklotz H, Massing U. Tailoring the Lamellarity of Liposomes Prepared by Dual Centrifugation. Pharmaceutics. 15. PMID 36840028 DOI: 10.3390/pharmaceutics15020706  0.379
2022 Steigenberger J, Mergen C, De Roo V, Geudens N, Martins JC, Heerklotz H. The effect of membrane thickness on the membrane permeabilizing activity of the cyclic lipopeptide tolaasin II. Frontiers in Molecular Biosciences. 9: 1064742. PMID 36619163 DOI: 10.3389/fmolb.2022.1064742  0.519
2022 Steigenberger J, Verleysen Y, Geudens N, Madder A, Martins JC, Heerklotz H. Complex electrostatic effects on the selectivity of membrane-permeabilizing cyclic lipopeptides. Biophysical Journal. PMID 35927958 DOI: 10.1016/j.bpj.2022.07.033  0.467
2021 Lan C, Stulz A, Barthes NPF, Lauw S, Salavei P, Jung M, Heerklotz H, Ulbrich MH. Designed membrane protein heterodimers and control of their affinity by binding domain and membrane linker properties. Nanoscale. PMID 34878479 DOI: 10.1039/d1nr06574b  0.397
2021 Steigenberger J, Verleysen Y, Geudens N, Martins JC, Heerklotz H. The Optimal Lipid Chain Length of a Membrane-Permeabilizing Lipopeptide Results From the Balance of Membrane Partitioning and Local Damage. Frontiers in Microbiology. 12: 669709. PMID 34594308 DOI: 10.3389/fmicb.2021.669709  0.406
2020 Dietel L, Kalie L, Heerklotz H. Lipid Scrambling Induced by Membrane-Active Substances. Biophysical Journal. PMID 32738218 DOI: 10.1016/J.Bpj.2020.07.004  0.613
2020 Stulz A, Breitsamer M, Winter G, Heerklotz H. Primary and Secondary Binding of Exenatide to Liposomes. Biophysical Journal. PMID 31972156 DOI: 10.1016/J.Bpj.2019.12.028  0.431
2020 Dietel L, Kalie L, Heerklotz HH. Lipid Scrambling of Asymmetric Liposomes Induced by Membrane Active Substances Biophysical Journal. 118: 89a. DOI: 10.1016/j.bpj.2019.11.652  0.476
2020 Kaiser M, Quarta N, Meister A, Heerklotz H. Vesicle Budding Induced by the Asymmetric Membrane Insertion of a Surfactant is Limited by an Osmotic Barrier Biophysical Journal. 118: 82a. DOI: 10.1016/J.Bpj.2019.11.619  0.551
2019 Markones M, Fippel A, Kaiser M, Drechsler C, Hunte C, Heerklotz H. Stairway to Asymmetry: Five Steps to Lipid-Asymmetric Proteoliposomes. Biophysical Journal. PMID 31843262 DOI: 10.1016/J.Bpj.2019.10.043  0.542
2019 Breitsamer M, Stulz A, Heerklotz HH, Winter G. Do interactions between Protein and Phospholipids influence the release behavior from lipid-based exenatide depot systems? European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik E.V. PMID 31195130 DOI: 10.1016/j.ejpb.2019.06.007  0.393
2019 Markones M, Fippel A, Kaiser M, Drechsler C, Hunte C, Heerklotz HH. Asymmetric Proteoliposomes - Striking a New Path in the World of Model Membranes Biophysical Journal. 116: 316a-317a. DOI: 10.1016/j.bpj.2018.11.1715  0.385
2018 Fuchs S, Hansen SC, Markones M, Mymrikov EV, Heerklotz H, Hunte C. Calcineurin B homologous protein 3 binds with high affinity to the CHP binding domain of the human sodium/proton exchanger NHE1. Scientific Reports. 8: 14837. PMID 30287853 DOI: 10.1038/S41598-018-33096-5  0.338
2018 Drechsler C, Markones M, Choi JY, Frieling N, Fiedler S, Voelker DR, Schubert R, Heerklotz H. Preparation of Asymmetric Liposomes Using a Phosphatidylserine Decarboxylase. Biophysical Journal. PMID 30266319 DOI: 10.1016/J.Bpj.2018.08.036  0.577
2018 Markones M, Zorzin C, Kaiser M, Kalie L, Heerklotz H, Fiedler S. Engineering asymmetric lipid vesicles: accurate and convenient control of the outer leaflet lipid composition. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 29294294 DOI: 10.1021/Acs.Langmuir.7B03189  0.542
2018 Dietel L, Huynh Q, Fiedler S, Heerklotz H. Synergistic Action of Fungicidal Lipopeptides as a Mechanism of Target Membrane Selectivity Biophysical Journal. 114: 452a. DOI: 10.1016/J.Bpj.2017.11.2501  0.46
2018 Fan HY, Quarta N, Heerklotz H. Quantifying Asymmetry in Detergent-Membrane Interactions Biophysical Journal. 114: 447a-448a. DOI: 10.1016/J.Bpj.2017.11.2475  0.542
2018 Braun S, Schnur J, Stulz A, Heerklotz HH, Hoernke M. Membrane Leakage: Further Insight by Advanced Statistical Analysis of Vesicle Leakage Biophysical Journal. 114: 261a. DOI: 10.1016/j.bpj.2017.11.1516  0.443
2017 Braun S, Pokorná Š, Šachl R, Hof M, Heerklotz H, Hoernke M. Biomembrane Permeabilization: Statistics of Individual Leakage Events Harmonize the Interpretation of Vesicle Leakage. Acs Nano. PMID 29244483 DOI: 10.1021/Acsnano.7B08184  0.534
2017 Fan HY, Heerklotz H. Digitonin does not flip across cholesterol-poor membranes. Journal of Colloid and Interface Science. 504: 283-293. PMID 28551523 DOI: 10.1016/J.Jcis.2017.05.034  0.591
2017 Braun S, Pokorná Š, Šachl R, Hof M, Heerklotz H, Hoernke M. GUV and LUV Leakage: How All-Or-None and Graded Leakage Scale with Vesicle Size Biophysical Journal. 112: 527a. DOI: 10.1016/J.Bpj.2016.11.2850  0.497
2017 Markones M, Zorzin C, Kalie L, Fiedler S, Heerklotz H. Tuning Membrane Asymmetry: Controlled Uptake of Negatively Charged Lipids into the Outer Leaflet of Liposomes Biophysical Journal. 112: 43a. DOI: 10.1016/J.Bpj.2016.11.271  0.555
2017 Stulz A, Römer W, Lienkamp K, Heerklotz H, Hoernke M. Lipid Clustering by Antimicrobial Polymers and Lectins Biophysical Journal. 112: 381a. DOI: 10.1016/J.Bpj.2016.11.2069  0.447
2016 Fan HY, Das D, Heerklotz H. "Staying out" rather than "cracking in": asymmetric membrane insertion of 12:0 lysophosphocholine. Langmuir : the Acs Journal of Surfaces and Colloids. PMID 27715063 DOI: 10.1021/Acs.Langmuir.6B03292  0.567
2016 Fan HY, Das D, Heerklotz H. Assessing Asymmetry in Detergent-Lipid Interactions with Isothermal Titration Calorimetry Biophysical Journal. 110: 70a. DOI: 10.1016/J.Bpj.2015.11.443  0.606
2015 Fiedler S, Heerklotz H. Vesicle Leakage Reflects the Target Selectivity of Antimicrobial Lipopeptides from Bacillus subtilis. Biophysical Journal. 109: 2079-89. PMID 26588567 DOI: 10.1016/J.Bpj.2015.09.021  0.485
2015 Lu S, Bennett WF, Ding Y, Zhang L, Fan HY, Zhao D, Zheng T, Ouyang PK, Li J, Wu Y, Xu W, Chu D, Yuan Y, Heerklotz H, Karttunen M, et al. Design and Characterization of a Multifunctional pH-Triggered Peptide C8 for Selective Anticancer Activity. Advanced Healthcare Materials. PMID 26474414 DOI: 10.1002/Adhm.201500636  0.343
2015 Hovakeemian SG, Liu R, Gellman SH, Heerklotz H. Correlating antimicrobial activity and model membrane leakage induced by nylon-3 polymers and detergents. Soft Matter. 11: 6840-51. PMID 26234884 DOI: 10.1039/C5Sm01521A  0.506
2015 Hovakeemian S, Liu R, Gellman SH, Heerklotz H. What Vesicle Leakage Reveals about Antimicrobial Activity (and What It Doesn't) Biophysical Journal. 108: 551a. DOI: 10.1016/J.Bpj.2014.11.3021  0.532
2015 Fiedler S, Huynh Q, Patel H, Heerklotz H. Lipid Selectivity of Fungicidal Lipopeptides Biophysical Journal. 108: 549a. DOI: 10.1016/J.Bpj.2014.11.3013  0.586
2015 Fan HY, Redka DS, Heerklotz H. Biophysical Analysis of a Successful Protocol to Reconstitute Tetramers of the M2 Muscarinic Receptor Biophysical Journal. 108: 543a. DOI: 10.1016/J.Bpj.2014.11.2978  0.503
2014 Patel H, Huynh Q, Bärlehner D, Heerklotz H. Additive and synergistic membrane permeabilization by antimicrobial (lipo)peptides and detergents. Biophysical Journal. 106: 2115-25. PMID 24853740 DOI: 10.1016/J.Bpj.2014.04.006  0.526
2014 Fan HY, Nazari M, Raval G, Khan Z, Patel H, Heerklotz H. Utilizing zeta potential measurements to study the effective charge, membrane partitioning, and membrane permeation of the lipopeptide surfactin. Biochimica Et Biophysica Acta. 1838: 2306-12. PMID 24631665 DOI: 10.1016/J.Bbamem.2014.02.018  0.715
2014 Shek YL, Noudeh GD, Nazari M, Heerklotz H, Abu-Ghazalah RM, Dubins DN, Chalikian TV. Folding thermodynamics of the hybrid-1 type intramolecular human telomeric G-quadruplex. Biopolymers. 101: 216-27. PMID 23775839 DOI: 10.1002/Bip.22317  0.542
2014 Hovakeemian SG, Liu R, Gellman SH, Heerklotz H. Membrane Leakage and Antimicrobial Action of Polymers and Surfactants Biophysical Journal. 106: 700a. DOI: 10.1016/J.Bpj.2013.11.3873  0.531
2014 Fan HY, Redka DS, Heerklotz H. Interaction of Digitonin and Cholate with Complex Membranes Biophysical Journal. 106: 700a. DOI: 10.1016/J.Bpj.2013.11.3872  0.589
2014 Patel H, Huynh Q, Bärlehner D, Heerklotz H. 1+1=3? Concerted Action of Membrane Permeabilizers Biophysical Journal. 106: 293a. DOI: 10.1016/J.Bpj.2013.11.1711  0.493
2013 Heerklotz H, Keller S. How membrane partitioning modulates receptor activation: parallel versus serial effects of hydrophobic ligands. Biophysical Journal. 105: 2607-10. PMID 24359728 DOI: 10.1016/J.Bpj.2013.10.031  0.387
2013 Redka DS, Heerklotz H, Wells JW. Efficacy as an intrinsic property of the M(2) muscarinic receptor in its tetrameric state. Biochemistry. 52: 7405-27. PMID 24047497 DOI: 10.1021/Bi4003869  0.314
2013 Das D, Shah A, Nazari M, Patel H, Heerklotz H. Characterizing the Interactions of Lysophospholipids with Lipid Membranes Biophysical Journal. 104: 81a. DOI: 10.1016/J.Bpj.2012.11.487  0.742
2013 Hovakeemian S, Patel H, Heerklotz H. Interactions of Cymal-6 and Lipid Vesicles Biophysical Journal. 104: 80a-81a. DOI: 10.1016/J.Bpj.2012.11.486  0.594
2013 Nazari M, Raval G, Khan Z, Patel H, Heerklotz H. Effective Charge and Membrane Binding, Mixing, and Permeation of Lipopeptides Characterized by Zeta Potential Measurements Biophysical Journal. 104: 44a. DOI: 10.1016/J.Bpj.2012.11.280  0.704
2013 Redka DS, Morizumi T, Paranthaman P, Heerklotz H, Ernst OP, Wells JW. Functional Comparison of Monomers and Tetramers of the M2 Muscarinic Receptor Biophysical Journal. 104: 26a. DOI: 10.1016/J.Bpj.2012.11.181  0.371
2012 Nazari M, Fan HY, Heerklotz H. Effect of hydrophobic interactions on volume and thermal expansivity as derived from micelle formation. Langmuir : the Acs Journal of Surfaces and Colloids. 28: 14129-36. PMID 22950856 DOI: 10.1021/La302276N  0.569
2012 Nazari M, Kurdi M, Heerklotz H. Classifying surfactants with respect to their effect on lipid membrane order. Biophysical Journal. 102: 498-506. PMID 22325272 DOI: 10.1016/J.Bpj.2011.12.029  0.734
2012 Nazari M, Kurdi M, Anis B, Heerklotz H. Superior Membrane Permeabilization and Solubilization Properties of Biosurfactants may be Explained by Heterogeneous Perturbation Biophysical Journal. 102: 96a. DOI: 10.1016/J.Bpj.2011.11.546  0.737
2012 Patel H, Fan H, Baerlehner D, Heerklotz H. Synergistic Membrane Permeation by Antifungal Lipopeptides and Detergents Biophysical Journal. 102: 93a. DOI: 10.1016/J.Bpj.2011.11.529  0.562
2012 Heerklotz H. Finding the Right Straw in a Haystack: How Lipid-Detergent Interactions may Affect the Solubilisation and Reconstitution of Membrane Proteins Biophysical Journal. 102: 439a. DOI: 10.1016/J.Bpj.2011.11.2406  0.587
2012 Heerklotz H, Blume A. Detergent interactions with lipid bilayers and membrane proteins Comprehensive Biophysics. 5: 63-91. DOI: 10.1016/B978-0-12-374920-8.00529-4  0.524
2011 Patel H, Tscheka C, Edwards K, Karlsson G, Heerklotz H. All-or-none membrane permeabilization by fengycin-type lipopeptides from Bacillus subtilis QST713. Biochimica Et Biophysica Acta. 1808: 2000-8. PMID 21545788 DOI: 10.1016/J.Bbamem.2011.04.008  0.412
2011 Fan HY, Nazari M, Chowdhury S, Heerklotz H. Volume and expansivity changes of micelle formation measured by pressure perturbation calorimetry. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 1693-9. PMID 21226468 DOI: 10.1021/La1042487  0.583
2011 Patel H, Tscheka C, Katarina E, Karlsson G, Heerklotz H. Showing the Potential of the Lifetime-Based Dye Leakage Assay: All-Or-None Membrane Permeabilization by Fungicidal Lipopeptides from Bacillus Subtilis QST 713 Biophysical Journal. 100: 335a. DOI: 10.1016/J.Bpj.2010.12.2035  0.441
2011 Shah A, Patel H, Nazari M, Heerklotz H. Interactions of Dodecylphosphocholine with Lipid Membranes Biophysical Journal. 100: 330a. DOI: 10.1016/J.Bpj.2010.12.2001  0.737
2011 Nazari M, Heerklotz H. Attack or Retreat: Two Modes of Membrane Solubilisation by Surfactants Biophysical Journal. 100: 330a. DOI: 10.1016/J.Bpj.2010.12.2000  0.74
2010 Patel H, Raval G, Nazari M, Heerklotz H. Effects of glycerol and urea on micellization, membrane partitioning and solubilization by a non-ionic surfactant. Biophysical Chemistry. 150: 119-28. PMID 20417021 DOI: 10.1016/J.Bpj.2010.12.1999  0.733
2010 Williams JA, Shaikh SR, LoCascio DS, Görgülü ST, Heerklotz H, Stillwell W, Wassall S. α-Tocopherol and Polyunsaturated Fatty Acid Membrane Domians Biophysical Journal. 98: 491a. DOI: 10.1016/J.Bpj.2009.12.2672  0.487
2010 Patel H, Nazari M, Tscheka C, Edwards K, Karlsson G, Heerklotz H. Different Scenarios of Membrane Permeabilization by Bacterial Lipopeptides Biophysical Journal. 98: 436a. DOI: 10.1016/J.Bpj.2009.12.2367  0.715
2010 Nazari M, Kurdi M, Patel H, Heerklotz H. Effects of Bacillus Lipopeptides on Lipid Membrane Structure and Dynamics Biophysical Journal. 98: 278a. DOI: 10.1016/J.Bpj.2009.12.1519  0.707
2009 Heerklotz H, Tsamaloukas AD, Keller S. Monitoring detergent-mediated solubilization and reconstitution of lipid membranes by isothermal titration calorimetry. Nature Protocols. 4: 686-97. PMID 19373233 DOI: 10.1038/Nprot.2009.35  0.587
2009 Tsamaloukas AD, Beck A, Heerklotz H. Modeling the micellization behavior of mixed and pure n-alkyl-maltosides. Langmuir : the Acs Journal of Surfaces and Colloids. 25: 4393-401. PMID 19366219 DOI: 10.1021/La8033935  0.317
2009 Rayan G, Tsamaloukas AD, Macgregor RB, Heerklotz H. Helix-coil transition of DNA monitored by pressure perturbation calorimetry. The Journal of Physical Chemistry. B. 113: 1738-42. PMID 19159195 DOI: 10.1021/Jp808253T  0.303
2009 Patel H, Tscheka C, Heerklotz H. Characterizing vesicle leakage by fluorescence lifetime measurements Soft Matter. 5: 2849-2851. DOI: 10.1016/J.Bpj.2009.12.454  0.466
2009 Patel H, Tsamaloukas A, Heerklotz H. The Effect Of Glycerol On Membrane Solubilization By Nonionic Surfactants Biophysical Journal. 96: 163a-164a. DOI: 10.1016/J.Bpj.2008.12.752  0.566
2009 Samuel N, Tsamaloukas A, Heerklotz H. Modeling The Temperature Dependence of Membrane Solubilization by Detergents Biophysical Journal. 96: 163a. DOI: 10.1016/J.Bpj.2008.12.748  0.536
2009 Patel H, Heerklotz H. Learning From A Bacillus How To Kill Fungi Biophysical Journal. 96: 154a. DOI: 10.1016/J.Bpj.2008.12.696  0.487
2009 Williams JA, LoCascio DS, Tsamaloukas A, Heerklotz H, Stillwell W, Wassall SR. Preferential Interaction of α-tocopherol with PUFA-containing Lipids Characterized by Isothermal Titration Calorimetry Biophysical Journal. 96: 608a. DOI: 10.1016/J.Bpj.2008.12.3213  0.452
2009 Nazari M, Heerklotz H. Shedding (UV) Light On The Interactions Of Paclitaxel With Liposomes Biophysical Journal. 96: 349a. DOI: 10.1016/J.Bpj.2008.12.1756  0.55
2008 Heerklotz H. Interactions of surfactants with lipid membranes. Quarterly Reviews of Biophysics. 41: 205-64. PMID 19079805 DOI: 10.1017/S0033583508004721  0.594
2008 Beck A, Tsamaloukas AD, Jurcevic P, Heerklotz H. Additive action of two or more solutes on lipid membranes. Langmuir : the Acs Journal of Surfaces and Colloids. 24: 8833-40. PMID 18646725 DOI: 10.1021/La800682Q  0.525
2007 Tsamaloukas AD, Keller S, Heerklotz H. Uptake and release protocol for assessing membrane binding and permeation by way of isothermal titration calorimetry. Nature Protocols. 2: 695-704. PMID 17406632 DOI: 10.1038/Nprot.2007.98  0.528
2007 Heerklotz H, Seelig J. Leakage and lysis of lipid membranes induced by the lipopeptide surfactin. European Biophysics Journal : Ebj. 36: 305-14. PMID 17051366 DOI: 10.1007/S00249-006-0091-5  0.546
2006 Tsamaloukas A, Szadkowska H, Heerklotz H. Nonideal mixing in multicomponent lipid/detergent systems. Journal of Physics. Condensed Matter : An Institute of Physics Journal. 18: S1125-38. PMID 21690833 DOI: 10.1088/0953-8984/18/28/S02  0.535
2006 Heerklotz H, Tsamaloukas A. Gradual change or phase transition: characterizing fluid lipid-cholesterol membranes on the basis of thermal volume changes. Biophysical Journal. 91: 600-7. PMID 16632513 DOI: 10.1529/Biophysj.106.082669  0.467
2006 Tsamaloukas A, Szadkowska H, Heerklotz H. Thermodynamic comparison of the interactions of cholesterol with unsaturated phospholipid and sphingomyelins. Biophysical Journal. 90: 4479-87. PMID 16581844 DOI: 10.1529/Biophysj.105.080127  0.505
2006 Keller S, Heerklotz H, Jahnke N, Blume A. Thermodynamics of lipid membrane solubilization by sodium dodecyl sulfate. Biophysical Journal. 90: 4509-21. PMID 16581838 DOI: 10.1529/Biophysj.105.077867  0.6
2006 Keller S, Heerklotz H, Blume A. Monitoring lipid membrane translocation of sodium dodecyl sulfate by isothermal titration calorimetry. Journal of the American Chemical Society. 128: 1279-86. PMID 16433546 DOI: 10.1021/Ja056389D  0.568
2005 Keller S, Tsamaloukas A, Heerklotz H. A quantitative model describing the selective solubilization of membrane domains. Journal of the American Chemical Society. 127: 11469-76. PMID 16089477 DOI: 10.1021/Ja052764Q  0.501
2005 Lichtenberg D, Goñi FM, Heerklotz H. Detergent-resistant membranes should not be identified with membrane rafts. Trends in Biochemical Sciences. 30: 430-6. PMID 15996869 DOI: 10.1016/J.Tibs.2005.06.004  0.554
2005 Tsamaloukas A, Szadkowska H, Slotte PJ, Heerklotz H. Interactions of cholesterol with lipid membranes and cyclodextrin characterized by calorimetry. Biophysical Journal. 89: 1109-19. PMID 15923231 DOI: 10.1529/Biophysj.105.061846  0.588
2004 Heerklotz H. The microcalorimetry of lipid membranes Journal of Physics Condensed Matter. 16. DOI: 10.1088/0953-8984/16/15/R01  0.597
2004 Heerklotz H, Wieprecht T, Seelig J. Membrane perturbation by the lipopeptide surfactin and detergents as studied by deuterium NMR Journal of Physical Chemistry B. 108: 4909-4915. DOI: 10.1021/Jp0371938  0.588
2004 Heerklotz H, Wieprecht T, Seelig J. Membrane Perturbation by the Lipopeptide Surfactin and Detergents as Studied by Deuterium NMR Journal of Physical Chemistry B. 108: 4909-4915.  0.527
2003 Heerklotz H, Szadkowska H, Anderson T, Seelig J. The sensitivity of lipid domains to small perturbations demonstrated by the effect of Triton. Journal of Molecular Biology. 329: 793-9. PMID 12787678 DOI: 10.1016/S0022-2836(03)00504-7  0.532
2002 Heerklotz H. Triton promotes domain formation in lipid raft mixtures Biophysical Journal. 83: 2693-2701. PMID 12414701 DOI: 10.1016/S0006-3495(02)75278-8  0.562
2002 Heerklotz H, Seelig J. Application of pressure perturbation calorimetry to lipid bilayers. Biophysical Journal. 82: 1445-52. PMID 11867459 DOI: 10.1016/S0006-3495(02)75498-2  0.336
2001 Heerklotz H, Seelig J. Detergent-like action of the antibiotic peptide surfactin on lipid membranes. Biophysical Journal. 81: 1547-54. PMID 11509367 DOI: 10.1016/S0006-3495(01)75808-0  0.509
2001 Heerklotz H. Membrane stress and permeabilization induced by asymmetric incorporation of compounds Biophysical Journal. 81: 184-195. PMID 11423405 DOI: 10.1016/S0006-3495(01)75690-1  0.537
2001 Heerklotz H, Epand RM. The enthalpy of acyl chain packing and the apparent water-accessible apolar surface area of phospholipids Biophysical Journal. 80: 271-279. PMID 11159400 DOI: 10.1016/S0006-3495(01)76012-2  0.333
2000 Heerklotz H, Seelig J. Titration calorimetry of surfactant-membrane partitioning and membrane solubilization. Biochimica Et Biophysica Acta. 1508: 69-85. PMID 11090819 DOI: 10.1016/S0304-4157(00)00009-5  0.589
2000 Heerklotz H, Seelig J. Correlation of membrane/water partition coefficients of detergents with the critical micelle concentration. Biophysical Journal. 78: 2435-40. PMID 10777739 DOI: 10.1016/S0006-3495(00)76787-7  0.514
1998 Lantzsch G, Binder H, Heerklotz H, Welzel P, Klose G. Aggregation behavior of the antibiotic moenomycin A in aqueous solution Langmuir. 14: 4095-4104. DOI: 10.1021/La980214I  0.334
1997 Heerklotz H, Binder H, Lantzsch G, Klose G, Blume A. Lipid/detergent interaction thermodynamics as a function of molecular shape Journal of Physical Chemistry B. 101: 639-645. DOI: 10.1021/Jp962342Q  0.426
1996 Heerklotz H, Lantzsch G, Binder H, Klose G, Blume A. Thermodynamic characterization of dilute aqueous lipid/detergent mixtures of POPC and C12EO8 by means of isothermal titration calorimetry Journal of Physical Chemistry. 100: 6764-6774. DOI: 10.1021/Jp9523534  0.548
1996 Lantzsch G, Binder H, Heerklotz H, Wendling M, Klose G. Surface areas and packing constraints in POPC/C12EOn membranes. A time-resolved fluorescence study Biophysical Chemistry. 58: 289-302. DOI: 10.1016/0301-4622(95)00108-5  0.454
1995 Heerklotz H, Lantzsch G, Binder H, Klose G, Blume A. Application of isothermal titration calorimetry for detecting lipid membrane solubilization Chemical Physics Letters. 235: 517-520. DOI: 10.1016/0009-2614(95)00139-U  0.559
1994 Heerklotz H, Binder H, Lantzsch G, Klose G. Membrane/water partition of oligo( ethylene oxide) dodecyl ethers and its relevance for solubilization Bba - Biomembranes. 1196: 114-122. PMID 7841174 DOI: 10.1016/0005-2736(94)00222-3  0.538
1994 Heerklotz H, Binder H, Lantzsch G. Determination of the partition coefficients of the nonionic detergent C12E7 between lipid-detergent mixed membranes and water by means of Laurdan fluorescence spectroscopy Journal of Fluorescence. 4: 349-352. DOI: 10.1007/Bf01881454  0.55
1994 Lantzsch G, Binder H, Heerklotz H. Surface area per molecule in lipid/C12En membranes as seen by fluorescence resonance energy transfer Journal of Fluorescence. 4: 339-343. DOI: 10.1007/Bf01881452  0.462
Low-probability matches (unlikely to be authored by this person)
2011 Fan HY, Shek YL, Amiri A, Dubins DN, Heerklotz H, Macgregor RB, Chalikian TV. Volumetric characterization of sodium-induced G-quadruplex formation. Journal of the American Chemical Society. 133: 4518-26. PMID 21370889 DOI: 10.1021/Ja110495C  0.298
2004 Heerklotz H, Tsamaloukas A, Kita-Tokarczyk K, Strunz P, Gutberlet T. Structural, volumetric, and thermodynamic characterization of a micellar sphere-to-rod transition. Journal of the American Chemical Society. 126: 16544-52. PMID 15600359 DOI: 10.1021/Ja045525W  0.294
2018 Eckhardt D, Li-Blatter X, Schönfeld HJ, Heerklotz H, Seelig J. Cooperative unfolding of apolipoprotein A-1 induced by chemical denaturation. Biophysical Chemistry. 240: 42-49. PMID 29885564 DOI: 10.1016/J.Bpc.2018.05.005  0.291
2011 Redka DS, Heerklotz H, Wells JW. Cooperativity in the Binding of Agonists to Reconstituted Tetramers of the M2 Muscarinic Receptor Biophysical Journal. 100: 420a. DOI: 10.1016/J.Bpj.2010.12.2487  0.291
2022 Vormittag LC, Heerklotz H. Extending the Pseudo-Phase Model of Detergent-Lipid Dispersions by a Detergent-Binding Protein. Langmuir : the Acs Journal of Surfaces and Colloids. 38: 15592-15603. PMID 36480936 DOI: 10.1021/acs.langmuir.2c02234  0.29
2021 Koehler JK, Schnur J, Heerklotz H, Massing U. Screening for Optimal Liposome Preparation Conditions by Using Dual Centrifugation and Time-Resolved Fluorescence Measurements. Pharmaceutics. 13. PMID 34959327 DOI: 10.3390/pharmaceutics13122046  0.285
2010 Redka DS, Heerklotz H, Wells JW. Efficacy As An Intrinsic Property of the M2 Muscarinic Receptor in Its Oligomeric State Biophysical Journal. 98: 34a. DOI: 10.1016/J.Bpj.2009.12.202  0.285
2010 Lee S, Heerklotz H, Chalikian TV. Effects of buffer ionization in protein transition volumes. Biophysical Chemistry. 148: 144-7. PMID 20346569 DOI: 10.1016/J.Bpc.2010.03.002  0.282
2015 Fan HY, Raval G, Shalviri A, May S, Wu XY, Heerklotz H. Coupled equilibria of a self-associating drug loaded into polymeric nanoparticles. Methods (San Diego, Calif.). 76: 162-70. PMID 25575744 DOI: 10.1016/J.Ymeth.2014.12.015  0.28
2019 Heerklotz H, London E. Kiss and Run Asymmetric Vesicles to Investigate Coupling. Biophysical Journal. PMID 31477242 DOI: 10.1016/J.Bpj.2019.07.053  0.273
2020 Regenold M, Steigenberger J, Siniscalchi E, Dunne M, Casettari L, Heerklotz H, Allen C. Determining critical parameters that influence in vitro performance characteristics of a thermosensitive liposome formulation of vinorelbine. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 32896612 DOI: 10.1016/J.Jconrel.2020.08.059  0.273
1998 Heerklotz HH, Binder H, Schmiedel H. Excess enthalpies of mixing in phospholipid-additive membranes Journal of Physical Chemistry B. 102: 5363-5368.  0.266
2020 Liang S, Fuchs S, Mymrikov EV, Stulz A, Kaiser M, Heerklotz H, Hunte C. Calcium affects CHP1 and CHP2 conformation and their interaction with sodium/proton exchanger 1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 31912575 DOI: 10.1096/Fj.201902093R  0.258
2007 Paul R, Abel S, Wassmann P, Beck A, Heerklotz H, Jenal U. Activation of the diguanylate cyclase PleD by phosphorylation-mediated dimerization. The Journal of Biological Chemistry. 282: 29170-7. PMID 17640875 DOI: 10.1074/Jbc.M704702200  0.258
1999 Binder H, Kohlstrunk B, Heerklotz HH. A humidity titration calorimetry technique to study the thermodynamics of hydration Chemical Physics Letters. 304: 329-335.  0.255
2013 Shalviri A, Chan HK, Raval G, Abdekhodaie MJ, Liu Q, Heerklotz H, Wu XY. Design of pH-responsive nanoparticles of terpolymer of poly(methacrylic acid), polysorbate 80 and starch for delivery of doxorubicin. Colloids and Surfaces. B, Biointerfaces. 101: 405-13. PMID 23010048 DOI: 10.1016/J.Colsurfb.2012.07.015  0.251
2011 Frenkel M, Diky V, Chirico RD, Goldberg RN, Heerklotz H, Ladbury JE, Remeta DP, Dymond JH, Goodwin ARH, Marsh KN, Wakeham WA, Stein SE, Brown PL, Königsberger E, Williams PA. ThermoML: An XML-based approach for storage and exchange of experimental and critically evaluated thermophysical and thermochemical property data. 5. Speciation and complex equilibria Journal of Chemical and Engineering Data. 56: 307-316. DOI: 10.1021/Je100999J  0.25
2007 Wassmann P, Chan C, Paul R, Beck A, Heerklotz H, Jenal U, Schirmer T. Structure of BeF3- -modified response regulator PleD: implications for diguanylate cyclase activation, catalysis, and feedback inhibition. Structure (London, England : 1993). 15: 915-27. PMID 17697997 DOI: 10.1016/J.Str.2007.06.016  0.244
2012 Shalviri A, Raval G, Prasad P, Chan C, Liu Q, Heerklotz H, Rauth AM, Wu XY. pH-Dependent doxorubicin release from terpolymer of starch, polymethacrylic acid and polysorbate 80 nanoparticles for overcoming multi-drug resistance in human breast cancer cells. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 82: 587-97. PMID 22995704 DOI: 10.1016/J.Ejpb.2012.09.001  0.243
2010 Chirico RD, Frenkel M, Diky V, Goldberg RN, Heerklotz H, Ladbury JE, Remeta DP, Dymond JH, Goodwin ARH, Marsh KN, Wakeham WA. ThermoML -An XML-based approach for storage and exchange of experimental and critically evaluated thermophysical and thermochemical property data. 4. biomaterials Journal of Chemical and Engineering Data. 55: 1564-1572. DOI: 10.1021/Je900685D  0.24
2018 Liang S, Fuchs S, Hansen SC, Markones M, Mymrikov E, Heerklotz H, Hunte C. Calcineurin-homologous proteins bind with high affinity to the CBD-region of the human Na+/H+ exchanger NHE1 Biochimica Et Biophysica Acta (Bba) - Bioenergetics. 1859: e96. DOI: 10.1016/J.Bbabio.2018.09.285  0.237
2011 Frenkel M, Chirico RD, Diky V, Brown PL, Dymond JH, Goldberg RN, Goodwin ARH, Heerklotz H, Königsberger E, Ladbury JE, Marsh KN, Remeta DP, Stein SE, Wakeham WA, Williams PA. Extension of ThermoML: The IUPAC standard for thermodynamic data communications (IUPAC Recommendations 2011) Pure and Applied Chemistry. 83: 1937-1969. DOI: 10.1351/Pac-Rec-11-05-01  0.235
2000 Gutberlet T, Kiselev M, Heerklotz H, Klose G. SANS study of mixed POPC/C12En aggregates Physica B: Condensed Matter. 276: 381-383. DOI: 10.1016/S0921-4526(99)01499-4  0.229
2021 Naßwetter LC, Fischer M, Scheidt HA, Heerklotz H. Membrane-water partitioning - Tackling the challenges of poorly soluble drugs using chaotropic co-solvents. Biophysical Chemistry. 277: 106654. PMID 34265547 DOI: 10.1016/j.bpc.2021.106654  0.228
1999 Heerklotz HH, Binder H, Epand RM. A 'release' protocol for isothermal titration calorimetry Biophysical Journal. 76: 2606-2613. PMID 10233075  0.224
2007 Mrosek M, Labeit D, Witt S, Heerklotz H, von Castelmur E, Labeit S, Mayans O. Molecular determinants for the recruitment of the ubiquitin-ligase MuRF-1 onto M-line titin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1383-92. PMID 17215480 DOI: 10.1096/Fj.06-7644Com  0.22
2021 Knoch H, Ulbrich MH, Mittag JJ, Buske J, Garidel P, Heerklotz H. Complex Micellization Behavior of the Polysorbates Tween 20 and Tween 80. Molecular Pharmaceutics. PMID 34251210 DOI: 10.1021/acs.molpharmaceut.1c00406  0.208
2010 Heerklotz H. Complex lipid–surfactant mixtures: a waste of good physical chemistry on a dirty system? Chemistry and Physics of Lipids. 163: S1-S2. DOI: 10.1016/J.Chemphyslip.2010.05.006  0.202
2005 Barrow DJ, Chandrasekaran S, Heerklotz HH, Henary MM, Michniak BB, Nguyen PM, Song Y, Smith JC, Strekowski L. Mechanistic studies on percutaneous penetration enhancement by N-(4-halobenzoyl)-S,S-dimethyliminosulfuranes Journal of Lipid Research. 46: 2192-2201. PMID 16061953 DOI: 10.1194/Jlr.M500123-Jlr200  0.196
1999 Binder H, Kohlstrunk B, Heerklotz HH. Hydration and lyotropic melting of amphiphilic molecules: A thermodynamic study using humidity titration calorimetry Journal of Colloid and Interface Science. 220: 235-249. DOI: 10.1006/jcis.1999.6501  0.177
2020 Eckhardt D, Schnur J, Steigenberger J, Kalie L, Massing U, Pabst G, Heerklotz HH. Eutectic Explains Function of Thermoresponsive Liposomes - Resolving the Lysolipid Paradox Biophysical Journal. 118: 227a. DOI: 10.1016/J.Bpj.2019.11.1346  0.129
2019 Schnur J, Eckhardt D, Massing U, Heerklotz HH. Interaction of Thermoresponsive Liposome Components with Human Serum Albumin Biophysical Journal. 116: 370a. DOI: 10.1016/j.bpj.2018.11.2015  0.097
2007 Wassmann P, Chan C, Paul R, Beck A, Heerklotz H, Jenal U, Schirmer T. Structure of BeF3--Modified Response Regulator PleD: Implications for Diguanylate Cyclase Activation, Catalysis, and Feedback Inhibition (DOI:10.1016/j.str.2007.06.016) Structure. 15: 1155. DOI: 10.1016/j.str.2007.08.006  0.07
2023 Heerklotz H. Who wants yesterday's papers? Biophysical Journal. 122: E1-E2. PMID 37673070 DOI: 10.1016/j.bpj.2023.08.017  0.011
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