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Lien T. Nguyen - Publications

Affiliations: 
2011-2016 Chemistry University of Illinois, Urbana-Champaign, Urbana-Champaign, IL 
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12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Guo S, Nguyen L, Ranum LPW. RAN proteins in neurodegenerative disease: Repeating themes and unifying therapeutic strategies. Current Opinion in Neurobiology. 72: 160-170. PMID 34953315 DOI: 10.1016/j.conb.2021.11.001  0.372
2021 Tusi SK, Nguyen L, Thangaraju K, Li J, Cleary JD, Zu T, Ranum LPW. The alternative initiation factor eIF2A plays key role in RAN translation of myotonic dystrophy type 2 CCUG•CAGG repeats. Human Molecular Genetics. PMID 33856033 DOI: 10.1093/hmg/ddab098  0.399
2020 Zu T, Guo S, Bardhi O, Ryskamp DA, Li J, Khoramian Tusi S, Engelbrecht A, Klippel K, Chakrabarty P, Nguyen L, Golde TE, Sonenberg N, Ranum LPW. Metformin inhibits RAN translation through PKR pathway and mitigates disease in ALS/FTD mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 32690681 DOI: 10.1073/Pnas.2005748117  0.393
2017 DiGiacomo V, de Opakua AI, Papakonstantinou MP, Nguyen LT, Merino N, Blanco-Canosa JB, Blanco FJ, Garcia-Marcos M. The Gαi-GIV binding interface is a druggable protein-protein interaction. Scientific Reports. 7: 8575. PMID 28819150 DOI: 10.1038/s41598-017-08829-7  0.327
2016 Bai Y, Nguyen LT, Song Z, Peng S, Lee J, Zheng N, Kapoor I, Hagler LD, Cai K, Cheng J, Chan HY, Zimmerman SC. Integrating Display and Delivery Functionality with a Cell Penetrating Peptide Mimic as a Scaffold for Intracellular Multivalent Multi-targeting. Journal of the American Chemical Society. PMID 27355522 DOI: 10.1021/Jacs.6B03697  0.691
2016 Luu LM, Nguyen L, Peng S, Lee J, Lee HY, Wong CH, Hergenrother PJ, Chan HY, Zimmerman SC. A Potent Inhibitor of Protein Sequestration by Expanded Triplet (CUG) Repeats that Shows Phenotypic Improvements in a Drosophila Model of Myotonic Dystrophy. Chemmedchem. PMID 27245480 DOI: 10.1002/Cmdc.201600081  0.658
2015 Nguyen L, Luu LM, Peng S, Serrano JF, Chan HY, Zimmerman SC. Rationally Designed Small Molecules That Target Both the DNA and RNA Causing Myotonic Dystrophy Type 1. Journal of the American Chemical Society. PMID 26473464 DOI: 10.1021/Jacs.5B09266  0.593
2014 Nguyen L, Lee J, Wong CH, Zimmerman SC. Small molecules that target the toxic RNA in myotonic dystrophy type 2. Chemmedchem. 9: 2455-62. PMID 24938413 DOI: 10.1002/Cmdc.201402095  0.682
2014 Wong CH, Nguyen L, Peh J, Luu LM, Sanchez JS, Richardson SL, Tuccinardi T, Tsoi H, Chan WY, Chan HY, Baranger AM, Hergenrother PJ, Zimmerman SC. Targeting toxic RNAs that cause myotonic dystrophy type 1 (DM1) with a bisamidinium inhibitor. Journal of the American Chemical Society. 136: 6355-61. PMID 24702247 DOI: 10.1021/Ja5012146  0.657
2014 Nguyen L, Lee J, Wong C, Zimmerman SC. Cover Picture: Small Molecules that Target the Toxic RNA in Myotonic Dystrophy Type 2 (ChemMedChem 11/2014) Chemmedchem. 9: 2393-2393. DOI: 10.1002/Cmdc.201490040  0.649
2013 Jahromi AH, Fu Y, Miller KA, Nguyen L, Luu LM, Baranger AM, Zimmerman SC. Developing bivalent ligands to target CUG triplet repeats, the causative agent of myotonic dystrophy type 1. Journal of Medicinal Chemistry. 56: 9471-81. PMID 24188018 DOI: 10.1021/Jm400794Z  0.698
2013 Jahromi AH, Nguyen L, Fu Y, Miller KA, Baranger AM, Zimmerman SC. A novel CUG(exp)·MBNL1 inhibitor with therapeutic potential for myotonic dystrophy type 1. Acs Chemical Biology. 8: 1037-43. PMID 23480597 DOI: 10.1021/Cb400046U  0.71
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