Ke-He Ruan - Publications

The University of Texas Graduate School of Biomedical Sciences at Houston 
Biochemistry, General Biophysics, Pharmacology

176 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Li Y, Li QY, Ling QL, So SP, Ruan KH. A novel single-chain enzyme complex with chain reaction properties rapidly producing thromboxane A and exhibiting powerful anti-bleeding functions. Journal of Cellular and Molecular Medicine. PMID 31628732 DOI: 10.1111/jcmm.14711  0.8
2019 Allen D, Ruan CH, King B, Ruan KH. Recent advances and near future of insulin production and therapy. Future Medicinal Chemistry. 11: 1513-1517. PMID 31469334 DOI: 10.4155/fmc-2019-0134  0.72
2018 Wang W, Qin JJ, Voruganti S, Nijampatnam B, Velu SE, Ruan KH, Hu M, Zhou J, Zhang R. Discovery and Characterization of Dual Inhibitors of MDM2 and NFAT1 for Pancreatic Cancer Therapy. Cancer Research. PMID 30217928 DOI: 10.1158/0008-5472.CAN-17-3939  0.72
2018 Li Y, Xu A, Ling Q, Ruan KH. Advances in extracellular ligand recognition sites on prostanoid receptors. Future Medicinal Chemistry. PMID 29673264 DOI: 10.4155/fmc-2017-0319  0.56
2018 Ling QL, Mohite AJ, Murdoch E, Akasaka H, Li QY, So SP, Ruan KH. Creating a mouse model resistant to induced ischemic stroke and cardiovascular damage. Scientific Reports. 8: 1653. PMID 29374184 DOI: 10.1038/s41598-018-19661-y  0.8
2016 Ling QL, Murdoch E, Ruan KH. How can we address the controversies surrounding the use of NSAIDS in neurodegeneration? Future Medicinal Chemistry. PMID 27357618 DOI: 10.4155/fmc-2016-0084  0.56
2016 Akasaka H, Ruan KH. Identification of the two-phase mechanism of arachidonic acid regulating inflammatory prostaglandin E2 biosynthesis by targeting COX-2 and mPGES-1. Archives of Biochemistry and Biophysics. PMID 27177970 DOI: 10.1016/  0.56
2016 Akasaka H, Ruan KH. How can we target oxidative stress in the treatment of neurodegenerative diseases? Future Medicinal Chemistry. PMID 27173453 DOI: 10.4155/fmc-2016-0065  0.56
2016 Deng Y, Yang Z, Terry T, Pan S, Woodside DG, Wang J, Ruan K, Willerson JT, Dixon RA, Liu Q. Prostacyclin-producing human mesenchymal cells target H19 lncRNA to augment endogenous progenitor function in hindlimb ischaemia. Nature Communications. 7: 11276. PMID 27080438 DOI: 10.1038/ncomms11276  0.44
2016 Ma RS, Li QF, Wang AD, Zhang JH, Liu ZJ, Wu JH, Su XC, Ruan K. Determination of pseudocontact shifts of low-populated excited states by NMR chemical exchange saturation transfer. Physical Chemistry Chemical Physics : Pccp. PMID 27001533 DOI: 10.1039/c6cp01127f  0.68
2016 Tian R, Ruan K, Li L, Le J, Rao M. Towards Standardized Performance Evaluation of Camera-Based Driver State Sensing Technologies Sae Technical Papers. 2016. DOI: 10.4271/2016-01-1500  0.44
2016 Sherony R, Yi Q, Chien S, Brink J, Almutairi M, Ruan K, Niu W, Li L, Chen Y, Takahashi H. Development of Bicycle Carrier for Bicyclist Pre-Collision System Evaluation Sae Technical Papers. 2016. DOI: 10.4271/2016-01-1446  0.44
2016 Ruan K, Zha Y, Zhou Z, Yang P. A modified GAC model for extracting waterline from remotely sensed imagery International Journal of Remote Sensing. 37: 3961-3973. DOI: 10.1080/01431161.2016.1207263  0.48
2016 Wang X, Cheng X, Gao S, Song J, Ruan K, Li X. Room temperature exchange bias in SmFeO3 single crystal Journal of Magnetism and Magnetic Materials. 399: 170-174. DOI: 10.1016/j.jmmm.2015.09.074  0.52
2016 Cheng X, Ma C, Wang X, Meng D, Song J, Yang H, Ruan K. Microstructural and multiferroic properties in layered perovskite-related Sm6Ti4Fe2O20 Ceramics International. 42: 13642-13647. DOI: 10.1016/j.ceramint.2016.05.159  0.52
2016 Wu Y, Peng X, Ruan K, Hu Z. Improved image segmentation method based on morphological reconstruction Multimedia Tools and Applications. 1-13. DOI: 10.1007/s11042-015-3192-2  0.52
2016 Wei Q, Chen J, Mi J, Zhang J, Ruan K, Wu J. Frontispiece: NMR Backbone Assignment of Large Proteins by Using 13Cα-Only Triple-Resonance Experiments Chemistry - a European Journal. 22. DOI: 10.1002/chem.201682862  0.68
2015 Kang LJ, Xie JJ, Zhao L, Yi JJ, Huang YS, Ruan KF. [Evaluation criteria for rat skin anaphylactoid test]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 40: 4044-51. PMID 27062825 DOI: 10.4268/cjcmm20152028  0.44
2015 Ruan K, Zhu Y, Li C, Brazill JM, Zhai RG. Alternative splicing of Drosophila Nmnat functions as a switch to enhance neuroprotection under stress. Nature Communications. 6: 10057. PMID 26616331 DOI: 10.1038/ncomms10057  0.68
2015 Zhang H, Liu Y, Wu Y, Ruan K. Superhydrophilic and Highly Transparent TiO2 Films Prepared by Dip Coating for Photocatalytic Degradation of Methylene Blue. Journal of Nanoscience and Nanotechnology. 15: 2531-6. PMID 26413700 DOI: 10.1166/jnn.2015.9819  0.76
2015 Jin X, Sun W, Zhang Q, Ruan K, Cheng Y, Xu H, Xu Z, Li Q. Reduced energy offset via substitutional doping for efficient organic/inorganic hybrid solar cells. Optics Express. 23: A444-55. PMID 26072869 DOI: 10.1364/OE.23.00A444  0.44
2015 Wu Y, Zhao F, Piao X, Ruan K. Zn-doped CaTiO3 :Eu(3+) red phosphors for enhanced photoluminescence in white LEDs by solid-state reaction. Luminescence : the Journal of Biological and Chemical Luminescence. PMID 26014578 DOI: 10.1002/bio.2937  0.76
2015 Akasaka H, So SP, Ruan KH. Relationship of the Topological Distances and Activities between mPGES-1 and COX-2 versus COX-1: Implications of the Different Post-Translational Endoplasmic Reticulum Organizations of COX-1 and COX-2. Biochemistry. 54: 3707-15. PMID 25988363 DOI: 10.1021/acs.biochem.5b00339  0.56
2015 Xu Z, Gu C, Wang K, Ju J, Wang H, Ruan K, Feng Y. Arctigenic acid, the key substance responsible for the hypoglycemic activity of Fructus Arctii. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 22: 128-37. PMID 25636881 DOI: 10.1016/j.phymed.2014.11.006  0.52
2015 Wei B, Cui Y, Huang Y, Liu H, Li L, Li M, Ruan KC, Zhou Q, Wang C. Tom70 mediates Sendai virus-induced apoptosis on mitochondria. Journal of Virology. 89: 3804-18. PMID 25609812 DOI: 10.1128/JVI.02959-14  0.4
2015 Meng XH, Liu HG, Huang JH, Dai ST, Deng J, Ruan KM, Chen JM, Lin WX. Tunable deep ultraviolet femtosecond sum frequency laser based on Ba1-xB2-y-zO4SixAlyGaz crystal Wuli Xuebao/Acta Physica Sinica. 64. DOI: 10.7498/aps.64.164205  0.4
2015 Xu P, LÜ G, Zhang Y, Zhou M, Wen G, Wang Z, Zhang H, Xu J, Ruan K, Wu Y. The quantitative research of brittle-ductile deformation of Jiaojia fault-altered belt in Jiaodong Area Earth Science Frontiers. 22: 97-103. DOI: 10.13745/j.esf.2015.04.011  0.64
2015 Hung YC, Lin FJ, Hwang JC, Chang JK, Ruan KC. Wavelet fuzzy neural network with asymmetric membership function controller for electric power steering system via improved differential evolution Ieee Transactions On Power Electronics. 30: 2350-2362. DOI: 10.1109/TPEL.2014.2327693  0.4
2015 Zhang M, Chen X, Ruan K, Sun J, Zhu Y. Localization using self-organizing maps based on spring relaxation Proceedings - 17th Ieee International Conference On Computational Science and Engineering, Cse 2014, Jointly With 13th Ieee International Conference On Ubiquitous Computing and Communications, Iucc 2014, 13th International Symposium On Pervasive Systems, Algorithms, and Networks, I-Span 2014 and 8th International Conference On Frontier of Computer Science and Technology, Fcst 2014. 373-377. DOI: 10.1109/CSE.2014.97  0.52
2015 Sun J, Ruan K, Zhang M, Zhu Y, Chen X. An adaptive ranging model under changeable environment Proceedings - 2014 Ieee International Conference On Control Science and Systems Engineering, Ccsse 2014. 110-114. DOI: 10.1109/CCSSE.2014.7224519  0.68
2015 Chen X, Zhang M, Ruan K, Gong C, Zhang Y, Yang SX. A Ranging Model Based on BP Neural Network Intelligent Automation and Soft Computing. DOI: 10.1080/10798587.2015.1095484  0.52
2015 Cheng X, Wang X, Yang H, Ruan K, Li X. Multiferroic properties of the layered perovskite-related oxide La6(Ti0.67Fe0.33)6O20 Journal of Materials Chemistry C. 3: 4482-4489. DOI: 10.1039/c5tc00188a  0.52
2015 Ruan K, Ding K, Wang Y, Diao S, Shao Z, Zhang X, Jie J. Flexible graphene/silicon heterojunction solar cells Journal of Materials Chemistry A. 3: 14370-14377. DOI: 10.1039/c5ta03652f  0.68
2015 Wang XX, Cheng XY, Lin Y, Ma C, Ruan KQ, Li XG. Multiferroic properties of hexagonal Ba3Ti2MnO9 Rsc Advances. 5: 101544-101551. DOI: 10.1039/c5ra18392h  0.52
2015 Wu Y, Zhao F, Ruan K, Zhang H, Piao X. Synthesis of (Ca, Zn)TiO3:Eu3+ red phosphors via the sol-gel method and their luminescence properties Chemical Physics Letters. 633: 234-240. DOI: 10.1016/j.cplett.2015.05.053  0.76
2015 Ruan K, Pan JY, Cao HJ, Xiang XK, Li ZS, Shao S, Wu JJ. Study on C-O-S isotopes of Shimensi Tungsten Deposit in Dahutang Kuangwu Yanshi/ Journal of Mineralogy and Petrology. 35: 57-62.  0.64
2015 Bai Y, Zhang YL, Huang FF, Chen SL, Ruan K, Chen X. Determination of purity and content of recombinant β nerve growth factor stock solution by HPLC Chinese Journal of New Drugs. 24: 400-402.  0.4
2015 Wang YF, Feng Y, Ruan KF, Wu F, Zhang JQ, Zhao CC. The research of the heat-sensitive components indicating the reliability of Sanqi Yishen granules concentration process Chinese Journal of New Drugs. 24: 2266-2270.  0.52
2014 Wang Y, Zhu Y, Ruan K, Wei H, Feng Y. MDG-1, a polysaccharide from Ophiopogon japonicus, prevents high fat diet-induced obesity and increases energy expenditure in mice. Carbohydrate Polymers. 114: 183-9. PMID 25263880 DOI: 10.1016/j.carbpol.2014.08.013  0.68
2014 Yu T, Tao Y, Yang M, Chen P, Gao X, Zhang Y, Zhang T, Chen Z, Hou J, Zhang Y, Ruan K, Wang H, Hu R. Profiling human protein degradome delineates cellular responses to proteasomal inhibition and reveals a feedback mechanism in regulating proteasome homeostasis. Cell Research. 24: 1214-30. PMID 25223703 DOI: 10.1038/cr.2014.122  0.4
2014 Li B, Li L, Guan A, Dong Q, Ruan K, Hu R, Li Z. A smartphone controlled handheld microfluidic liquid handling system. Lab On a Chip. 14: 4085-92. PMID 25182078 DOI: 10.1039/c4lc00227j  0.44
2014 Liu Z, Chen P, Gao H, Gu Y, Yang J, Peng H, Xu X, Wang H, Yang M, Liu X, Fan L, Chen S, Zhou J, Sun Y, Ruan K, et al. Ubiquitylation of autophagy receptor Optineurin by HACE1 activates selective autophagy for tumor suppression. Cancer Cell. 26: 106-20. PMID 25026213 DOI: 10.1016/j.ccr.2014.05.015  0.48
2014 Shen J, Sheng X, Chang Z, Wu Q, Wang S, Xuan Z, Li D, Wu Y, Shang Y, Kong X, Yu L, Li L, Ruan K, Hu H, Huang Y, et al. Iron metabolism regulates p53 signaling through direct heme-p53 interaction and modulation of p53 localization, stability, and function. Cell Reports. 7: 180-93. PMID 24685134 DOI: 10.1016/j.celrep.2014.02.042  0.48
2014 Xu X, Tao Y, Fu X, Yu T, Li Y, Chen K, Ding X, Ruan K, Jing N, Hu R. ZIP-seq: genome-wide mapping of trinucleotide repeats at single-base resolution. Journal of Molecular Cell Biology. 6: 93-6. PMID 24334259 DOI: 10.1093/jmcb/mjt048  0.44
2014 Zhu Y, Cong W, Shen L, Wei H, Wang Y, Wang L, Ruan K, Wu F, Feng Y. Fecal metabonomic study of a polysaccharide, MDG-1 from Ophiopogon japonicus on diabetic mice based on gas chromatography/time-of-flight mass spectrometry (GC TOF/MS). Molecular Biosystems. 10: 304-12. PMID 24292023 DOI: 10.1039/c3mb70392d  0.68
2014 Vollert C, Ohia O, Akasaka H, Berridge C, Ruan KH, Eriksen JL. Elevated prostacyclin biosynthesis in mice impacts memory and anxiety-like behavior. Behavioural Brain Research. 258: 138-44. PMID 24140503 DOI: 10.1016/j.bbr.2013.10.012  0.56
2014 Shen J, Song G, An M, Li X, Wu N, Ruan K, Hu J, Hu R. The use of hollow mesoporous silica nanospheres to encapsulate bortezomib and improve efficacy for non-small cell lung cancer therapy. Biomaterials. 35: 316-26. PMID 24125776 DOI: 10.1016/j.biomaterials.2013.09.098  0.44
2014 Cong W, Shen L, Xu D, Zhao L, Ruan K, Feng Y. Solid dispersion tablets of breviscapine with polyvinylpyrrolidone K30 for improved dissolution and bioavailability to commercial breviscapine tablets in beagle dogs. European Journal of Drug Metabolism and Pharmacokinetics. 39: 203-10. PMID 24061692 DOI: 10.1007/s13318-013-0150-0  0.68
2014 Zhang X, Hong YL, Xu DS, Feng Y, Zhao LJ, Ruan KF, Yang XJ. A review of experimental research on herbal compounds in amyotrophic lateral sclerosis. Phytotherapy Research : Ptr. 28: 9-21. PMID 23519768 DOI: 10.1002/ptr.4960  0.68
2014 Ruan KP, Feng Y, Liu GP, Zhao LJ, Du RF, Zhu L. Quantification control of direct compression tableting of Chuanshenfang Chinese Traditional and Herbal Drugs. 45: 1262-1264. DOI: 10.7501/j.issn.0253-2670.2014.09.012  0.52
2014 Zhang W, Zhu S, Ruan K, Peng J. Barotropic instability mechanism analysis to development of low-salinity water lenses outside the Changjiang Estuary Jiefangjun Ligong Daxue Xuebao/Journal of Pla University of Science and Technology (Natural Science Edition). 15: 80-87. DOI: 10.3969/j.issn.1009-3443.2012.12.050  0.6
2014 Wu YB, Sun Z, Ruan KB, Liu YC, Zhang H. Structural and optical properties of Ca0.88TiO3∶0.12Eu3+ red phosphors Faguang Xuebao/Chinese Journal of Luminescence. 35: 932-938. DOI: 10.3788/fgxb20143508.0932  0.6
2014 Li XH, Zhao LJ, Ruan KP, Li MD, Feng Y, Xu DS, Ruan KF. Deformation mechanisms and compactibility of directly compressible excipients using induction tablet press Chinese Pharmaceutical Journal. 49: 849-857. DOI: 10.11669/cpj.2014.10.013  0.52
2014 Lin FJ, Hung YC, Ruan KC. An intelligent second-order sliding-mode control for an electric power steering system using a wavelet fuzzy neural network Ieee Transactions On Fuzzy Systems. 22: 1598-1611. DOI: 10.1109/TFUZZ.2014.2300168  0.4
2014 Liu H, Huang J, Tang F, Li J, Weng W, Ge Y, Zheng H, Ruan K, Shi F, Dai S, Deng J, Lin W. Generation of 3.8-GHz picosecond pulses from a diode-pumped self-mode-locked Yb:YAG thin disk laser Ieee Photonics Technology Letters. 26: 418-420. DOI: 10.1109/LPT.2013.2296293  0.6
2014 Zheng H, Huang JH, Zhao X, Wang JY, Shi F, Li JH, Deng J, Liu HG, Weng W, Ge Y, Dai ST, Ruan KM, Wu HC, Lin WX. An LD-pumped Q-switched Nd:YAG laser using La3Ga 5SiO14 for the electro-optic modulator and optical activity compensation Laser Physics. 24. DOI: 10.1088/1054-660X/24/4/045802  0.6
2014 Li Y, Zhu YY, Shi LL, Shen L, Wei H, Wang Y, Ruan KF, Feng Y. UPLC-TOF/MS based urinary metabonomic studies reveal mild prevention effects of MDG-1 on metabolic disorders in diet-induced obese mice Analytical Methods. 6: 4171-4180. DOI: 10.1039/c4ay00796d  0.68
2014 Han Y, Zhang L, Zhang X, Ruan K, Cui L, Wang Y, Liao L, Wang Z, Jie J. Clean surface transfer of graphene films via an effective sandwich method for organic light-emitting diode applications Journal of Materials Chemistry C. 2: 201-207. DOI: 10.1039/c3tc31722f  0.68
2014 Ma S, Shen L, Zhai Y, Lin X, Feng Y, Xu L, Ruan K. An integral evaluation method for synchronous drug release based on a mathematics set in guiding the preparation of multi-component traditional Chinese medicine Analytical Methods. 6: 2260-2269. DOI: 10.1039/c3ay41850b  0.68
2014 Gao P, Ding K, Wang Y, Ruan K, Diao S, Zhang Q, Sun B, Jie J. Crystalline Si/graphene quantum dots heterojunction solar cells Journal of Physical Chemistry C. 118: 5164-5171. DOI: 10.1021/jp412591k  0.68
2014 Ruan K, Zha Y, Huang H, Hu YB. Contribution of vortex Rossby wave to spiral rainband formation in tropical cyclones Journal of Hydrodynamics. 26: 725-733. DOI: 10.1016/S1001-6058(14)60081-0  0.32
2014 Yang H, Liu J, Leng R, Ruan K. Study on the magnetic susceptibility of Li1-xNaxCu2O2single crystals Solid State Communications. 197: 49-52. DOI: 10.1016/j.ssc.2014.08.013  0.36
2014 Wu Y, Sun Z, Ruan K, Xu Y, Zhang H. Enhancing photoluminescence with Li-doped CaTiO3:Eu3+ red phosphors prepared by solid state synthesis Journal of Luminescence. 155: 269-274. DOI: 10.1016/j.jlumin.2014.06.051  0.6
2014 Ali Y, Ruan K, Grace Zhai R. Drosophila Models of Tauopathy Movement Disorders: Genetics and Models: Second Edition. 829-848. DOI: 10.1016/B978-0-12-405195-9.00054-8  0.68
2014 Zhang Wj, Zhu Sx, Li Xq, Ruan K, Guan Wb, Peng J. Numerical simulation and dynamical analysis for low salinity water lens in the expansion area of the Changjiang diluted water China Ocean Engineering. 28: 777-790. DOI: 10.1007/s13344-014-0060-1  0.6
2014 Chen X, Zhang M, Ruan K, Xu G, Sun S, Gong C, Min J, Lei B. Improved mean shift target tracking based on self-organizing maps Signal, Image and Video Processing. 8: 103-112. DOI: 10.1007/s11760-014-0682-z  0.52
2014 Dai J, Li L, He LP, Ruan KC, Lu HB, Jin KJ, Yang GZ. Parallel detection and quantitative analysis of specific binding of proteins by oblique-incidence reflectivity difference technique in label-free format Science China: Physics, Mechanics and Astronomy. 57: 2039-2042. DOI: 10.1007/s11433-014-5481-6  0.44
2014 Wu F, Wang YJ, Zhang JQ, Hong YL, Feng Y, Ruan KF, Liu CL. Study on taste-modifying of Kang'erling granules Chinese Journal of New Drugs. 23: 701-705.  0.68
2014 Chillar A, So SP, Tang N, Ruan KH. Identification of tumorigenesis from the specific coupling of cyclooxygenase-2 with microsomal prostaglandin E2 synthase-1 in vivo European Journal of Inflammation. 12: 77-88.  0.56
2013 Li XH, Li MD, Du Y, Zhao LJ, Feng Y, Xu DS, Ruan KF. [Application of factor analysis to evaluate deformation behaviors of frequently-used tablet excipients]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 48: 1475-83. PMID 24358784  0.68
2013 Liu CL, Ruan KF, Gao JW, Wu F, Zhang JQ. [Multiple mechanisms of depression]. Sheng Li Ke Xue Jin Zhan [Progress in Physiology]. 44: 253-8. PMID 24228515  0.68
2013 Shen L, Zhai Y, Ma SY, Lin X, Feng Y, Ruan KF. [Comparative study on mathematical set-based drug release kinetics method and Kalman filter method applied in evaluating drug release of multi-component traditional Chinese medicine preparations]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 38: 1165-71. PMID 23944030 DOI: 10.4268/cjcmm20130811  0.68
2013 Zhou L, Chen Z, Vanderslice P, So SP, Ruan KH, Willerson JT, Dixon RA. Endothelial-like progenitor cells engineered to produce prostacyclin rescue monocrotaline-induced pulmonary arterial hypertension and provide right ventricle benefits. Circulation. 128: 982-94. PMID 23841984 DOI: 10.1161/CIRCULATIONAHA.113.003139  0.56
2013 Sun G, Lin X, Shen L, Wu F, Xu D, Ruan K, Feng Y. Mono-PEGylated radix ophiopogonis polysaccharide for the treatment of myocardial ischemia. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 49: 629-36. PMID 23727058 DOI: 10.1016/j.ejps.2013.05.020  0.68
2013 Yang XJ, Hong YL, Wu F, Ruan KF, Feng Y. [Determination of rhynchophylline and isorhynchophylline in Uncaria rhynchophylla by HPLC]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 38: 720-4. PMID 23724683 DOI: 10.4268/cjcmm20130521  0.68
2013 Cao J, Ma HY, Li HY, Wang KR, Ruan K, Bai LH. Halomonas socia sp. nov., isolated from high salt culture of Dunaliella salina. Extremophiles : Life Under Extreme Conditions. 17: 663-8. PMID 23722502 DOI: 10.1007/s00792-013-0549-1  0.72
2013 Du RC, Wang YJ, Wu F, Feng Y, Xu DS, Hong YL, Ruan KF. [Discrimination of traditional Chinese medicinal materials with different tastes based on electronic tongue]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 38: 154-60. PMID 23672033 DOI: 10.4268/cjcmm20130203  0.68
2013 Ruan KH, Mohite AJ, So SP. Resistant to thrombosis, induced stroke and heart arrest by incorporation of a single gene of PGI2-synthesizing COX-1-PGIS in vivo: Implication against human heart disease. International Journal of Cardiology. 168: 2960-1. PMID 23602873 DOI: 10.1016/j.ijcard.2013.03.114  0.56
2013 Lin H, Yuan J, Ruan KH, Yang W, Zhang J, Dai Y, Wang R. COX-2-10aa-PGIS gene therapy improves erectile function in rats after cavernous nerve injury. The Journal of Sexual Medicine. 10: 1476-87. PMID 23551902 DOI: 10.1111/jsm.12147  0.56
2013 Zhu Y, Feng Y, Shen L, Xu D, Wang B, Ruan K, Cong W. Effect of metformin on the urinary metabolites of diet-induced-obese mice studied by ultra performance liquid chromatography coupled to time-of-flight mass spectrometry (UPLC-TOF/MS). Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 925: 110-6. PMID 23523884 DOI: 10.1016/j.jchromb.2013.02.040  0.68
2013 Zang S, Ali YO, Ruan K, Zhai RG. Nicotinamide mononucleotide adenylyltransferase maintains active zone structure by stabilizing Bruchpilot. Embo Reports. 14: 87-94. PMID 23154466 DOI: 10.1038/embor.2012.181  0.68
2013 Ruan KH, Mohite A, So SP, Ruan CH. Establishing novel prostacyclin-synthesizing cells with therapeutic potential against heart diseases. International Journal of Cardiology. 163: 163-9. PMID 21722977 DOI: 10.1016/j.ijcard.2011.06.007  0.56
2013 Xia ZD, Ruan KQ. Improvement of coarse-mesh finite difference accelerated nodal method Yuanzineng Kexue Jishu/Atomic Energy Science and Technology. 47: 15-17. DOI: 10.7538/yzk.2013.47.S0.0015  0.44
2013 Li XH, Zhao LJ, Feng Y, Xu DS, Du Y, Ruan KF. Effect of physical properties of microcrystalline cellulose on its compressibility and compactability Chinese Pharmaceutical Journal. 48: 116-122. DOI: 10.11669/cpj.2013.02.010  0.68
2013 Wang YF, Zhang JQ, Wu F, Ruan KF. Update on the pathogenesis and clinical treatment of gastroesophageal reflux disease World Chinese Journal of Digestology. 21: 3821-3827. DOI: 10.11569/wcjd.v21.i34.3821  0.68
2013 Liu HG, Huang JH, Li JH, Weng W, Zheng H, Ge Y, Dai ST, Shi F, Ruan KM, Deng J, Wu HC, Lin WX. Above 100 nJ all-normal-dispersion femtosecond pulse generation from a large-core multi-mode fiber laser Laser Physics Letters. 10. DOI: 10.1088/1612-2011/10/5/055101  0.6
2013 Xie C, Zhang X, Ruan K, Shao Z, Dhaliwal SS, Wang L, Zhang Q, Jie J. High-efficiency, air stable graphene/Si micro-hole array Schottky junction solar cells Journal of Materials Chemistry A. 1: 15348-15354. DOI: 10.1039/c3ta13750c  0.68
2013 Li XH, Zhao LJ, Ruan KP, Feng Y, Xu DS, Ruan KF. The application of factor analysis to evaluate deforming behaviors of directly compressed powders Powder Technology. 247: 47-54. DOI: 10.1016/j.powtec.2013.06.040  0.52
2013 Zhu XZ, Han YY, Liu Y, Ruan KQ, Xu MF, Wang ZK, Jie JS, Liao LS. The application of single-layer graphene modified with solution-processed TiOx and PEDOT:PSS as a transparent conductive anode in organic light-emitting diodes Organic Electronics: Physics, Materials, Applications. 14: 3348-3354. DOI: 10.1016/j.orgel.2013.10.003  0.68
2013 Gao S, Lv YD, Wang XX, Yang HS, Ruan KQ, Li XG. Magnetic and dielectric properties of quasi-two-dimensional manganese oxide Sr7Mn4O15 Journal of Magnetism and Magnetic Materials. 328: 66-71. DOI: 10.1016/j.jmmm.2012.10.007  0.52
2013 Fang X, Lin X, Liang S, Zhang WD, Feng Y, Ruan KF. Phytochemical study of Hicriopteris glauca Chemistry of Natural Compounds. 49: 514-515. DOI: 10.1007/s10600-013-0655-4  0.68
2013 Zhi X, Xiao L, Liang S, Yi F, Ruan KF. Chemical constituents of Rhododendron molle Chemistry of Natural Compounds. 49: 454-456. DOI: 10.1007/s10600-013-0637-6  0.68
2013 Li XH, Li MD, Du Y, Zhao LJ, Feng Y, Xu DS, Ruan KF. An approach to acquire compaction parameters from the induction tablet press Korsch XP1 Chinese Journal of New Drugs. 22: 2301-2308.  0.68
2013 Ma WJ, Ruan K, Feng J, Shen Y. Optimizing algorithm for I/O performance of cloud storage system based on dynamic hybrid range mechanism Beijing Gongye Daxue Xuebao/Journal of Beijing University of Technology. 39: 707-712.  0.6
2013 Ruan K, Zhu S, Zhang X, Zeng W. Water depth inversion in Haikou Bay based on TM image International Conference On Remote Sensing, Environment and Transportation Engineering, Rsete 2013. 769-771.  0.4
2012 Chen WL, Guo DW, Shen YY, Guo SR, Ruan KP. Effects of highly hygroscopic excipients on the hydrolysis of simvastatin in tablet at high relative humidity. Indian Journal of Pharmaceutical Sciences. 74: 527-34. PMID 23798778 DOI: 10.4103/0250-474X.110587  0.52
2012 Fang X, Lin X, Liang S, Zhang WD, Feng Y, Ruan KF. Two new compounds from Hicriopteris glauca and their potential antitumor activities. Journal of Asian Natural Products Research. 14: 1175-9. PMID 23157308 DOI: 10.1080/10286020.2012.739615  0.68
2012 Ruan K, Ye F, Li C, Liou YC, Lin SC, Lin SY. PLK1 interacts and phosphorylates Axin that is essential for proper centrosome formation. Plos One. 7: e49184. PMID 23155463 DOI: 10.1371/journal.pone.0049184  0.48
2012 Shen L, Lin X, Hong Y, Liang S, Yuan Y, Feng Y, Xu D, Ruan K. [Study on HPLC characteristic fingerprint of active components of dachuanxiong fang in plasma and cerebrospinal fluid]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 37: 2017-21. PMID 23019890 DOI: 10.4268/cjcmm20121332  0.68
2012 Zhao LJ, Feng Y, Xu DS, Ruan KF, Hong YL, Fu XJ. [Multivariate analysis of relationships between material properties and hygroscopicity of Chinese medicine raw materials]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 47: 517-21. PMID 22799037  0.68
2012 Zhao HB, Hong YL, Wang YJ, Shen L, Wu F, Feng Y, Ruan KF. [Influence of combination on the specific chromatogram of Glycyrrhiza in sini decoctions by HPLC]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 47: 508-11. PMID 22799035  0.68
2012 Wang LY, Wang Y, Xu DS, Ruan KF, Feng Y, Wang S. MDG-1, a polysaccharide from Ophiopogon japonicus exerts hypoglycemic effects through the PI3K/Akt pathway in a diabetic KKAy mouse model. Journal of Ethnopharmacology. 143: 347-54. PMID 22776833 DOI: 10.1016/j.jep.2012.06.050  0.68
2012 Shen L, Hu R, Lin X, Hong Y, Feng Y, Xu D, Ruan K. [Pharmacokinetics effect of shaoyao gancao compound with different decocting methods on characteristic ingredients in rat plasma after oral administration]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 37: 52-6. PMID 22741461 DOI: 10.4268/cjcmm20120111  0.68
2012 Lin SY, Li TY, Liu Q, Zhang C, Li X, Chen Y, Zhang SM, Lian G, Liu Q, Ruan K, Wang Z, Zhang CS, Chien KY, Wu J, Li Q, et al. Protein phosphorylation-acetylation cascade connects growth factor deprivation to autophagy. Autophagy. 8: 1385-6. PMID 22717509 DOI: 10.4161/auto.20959  0.48
2012 Shen L, Cong WJ, Lin X, Hong YL, Hu RW, Feng Y, Xu DS, Ruan KF. Characterization using LC/MS of the absorption compounds and metabolites in rat plasma after oral administration of a single or mixed decoction of Shaoyao and Gancao. Chemical & Pharmaceutical Bulletin. 60: 712-21. PMID 22689421 DOI: DN/JST.JSTAGE/cpb/60.712  0.68
2012 He CY, Wang S, Feng Y, Liang S, Lin X, Xu DS, Ruan KF. Pharmacokinetics, tissue distribution and metabolism of senkyunolide I, a major bioactive component in Ligusticum chuanxiong Hort. (Umbelliferae). Journal of Ethnopharmacology. 142: 706-13. PMID 22668502 DOI: 10.1016/j.jep.2012.05.047  0.68
2012 Lin SY, Li TY, Liu Q, Zhang C, Li X, Chen Y, Zhang SM, Lian G, Liu Q, Ruan K, Wang Z, Zhang CS, Chien KY, Wu J, Li Q, et al. GSK3-TIP60-ULK1 signaling pathway links growth factor deprivation to autophagy. Science (New York, N.Y.). 336: 477-81. PMID 22539723 DOI: 10.1126/science.1217032  0.48
2012 Sun G, Lin X, Hong Y, Feng Y, Ruan K, Xu D. PEGylation for drug delivery to ischemic myocardium: pharmacokinetics and cardiac distribution of poly(ethylene glycol)s in mice with normal and ischemic myocardium. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 46: 545-52. PMID 22525436 DOI: 10.1016/j.ejps.2012.04.010  0.68
2012 Wu X, Zhao B, Li W, Chen Y, Liang R, Li L, Jin Y, Ruan K. MiR-200a is involved in rat epididymal development by targeting β-catenin mRNA. Acta Biochimica Et Biophysica Sinica. 44: 233-40. PMID 22240259 DOI: 10.1093/abbs/gmr122  0.44
2012 Wang S, Lin X, Wang LY, Ruan KF, Feng Y, Li XY. A polysaccharides MDG-1 augments survival in the ischemic heart by inducing S1P release and S1P1 expression. International Journal of Biological Macromolecules. 50: 734-40. PMID 22197795 DOI: 10.1016/j.ijbiomac.2011.12.005  0.68
2012 Shen L, Hu RW, Lin X, Cong WJ, Hong YL, Feng Y, Xu DS, Ruan KF. Pharmacokinetics of characteristic effective ingredients from individual and combination Shaoyao and Gancao treatment in rats using HPLC fingerprinting. European Journal of Drug Metabolism and Pharmacokinetics. 37: 133-40. PMID 21987053 DOI: 10.1007/s13318-011-0052-y  0.68
2012 Ali YO, Ruan K, Zhai RG. NMNAT suppresses tau-induced neurodegeneration by promoting clearance of hyperphosphorylated tau oligomers in a Drosophila model of tauopathy. Human Molecular Genetics. 21: 237-50. PMID 21965302 DOI: 10.1093/hmg/ddr449  0.68
2012 Liu Q, Xi Y, Terry T, So SP, Mohite A, Zhang J, Wu G, Liu X, Cheng J, Ruan KH, Willerson JT, Dixon RA. Engineered endothelial progenitor cells that overexpress prostacyclin protect vascular cells. Journal of Cellular Physiology. 227: 2907-16. PMID 21938725 DOI: 10.1002/jcp.23035  0.56
2012 Ou X, Zhou S, Wang Z, Ruan K, Li B. Application and research of slope flexible protection system in engineering Applied Mechanics and Materials. 204: 344-349. DOI: 10.4028/  0.68
2012 Ruan KB, Wu GH, Zhou H, Wu YB. Optical properties of Bi 3.45Eu 0.55Ti 3O 12 ferroelectric thin films Guangdian Gongcheng/Opto-Electronic Engineering. 39: 97-101. DOI: 10.3969/j.issn.1003-501X.2012.07.015  0.6
2012 Cong WJ, Liu QF, Liang QL, Luo GA, Ruan KF, Feng Y. Serum metabolites of commerical pirarubicin injections Chinese Pharmacological Bulletin. 28: 1294-1299. DOI: 10.3969/j.issn.1001-1978.2012.09.025  0.68
2012 Ruan KB, Wu GH, Zhou H, Liu YC. Structural and optical properties of Bi 3.15Eu 0.85Ti 3O 12 ferroelectric thin films Faguang Xuebao/Chinese Journal of Luminescence. 33: 754-759. DOI: 10.3788/fgxb20123307.0754  0.6
2012 Lu Y, Qi J, Guan P, Hu Y, Ruan K, Wu W. Micronization of solid dispersion pellets: Physical characterization and improved dissolution Advanced Science Letters. 6: 200-206. DOI: 10.1166/asl.2012.2013  0.52
2012 Green RJ, Boukhvalov DW, Kurmaev EZ, Finkelstein LD, Ho HW, Ruan KB, Wang L, Moewes A. Room-temperature ferromagnetism via unpaired dopant electrons and p-p coupling in carbon-doped In 2O 3: Experiment and theory Physical Review B - Condensed Matter and Materials Physics. 86. DOI: 10.1103/PhysRevB.86.115212  0.4
2012 Song G, Li C, Hu J, Zou R, Xu K, Han L, Wang Q, Yang J, Chen Z, Qin Z, Ruan K, Hu R. A simple transformation from silica core-shell-shell to yolk-shell nanostructures: A useful platform for effective cell imaging and drug delivery Journal of Materials Chemistry. 22: 17011-17018. DOI: 10.1039/c2jm32382f  0.44
2012 Chen X, Zhang H, Ruan K, Shi W. Annealing effect on the bipolar resistive switching behaviors of BiFeO 3 thin films on LaNiO 3-buffered Si substrates Journal of Alloys and Compounds. 529: 108-112. DOI: 10.1016/j.jallcom.2012.03.014  0.6
2012 Dai J, Li L, Wang J, He L, Lu H, Ruan K, Jin K, Yang G. Label-free detection repeatability of protein microarrays by oblique-incidence reflectivity difference method Science China: Physics, Mechanics and Astronomy. 55: 2347-2350. DOI: 10.1007/s11433-012-4952-x  0.44
2012 Ruan K, Wu G, Zhou H, Bao D. Optical characteristics of Bi 4-xEu xTi 3O 12 ferroelectric thin films on fused silica substrates Journal of Electroceramics. 29: 37-41. DOI: 10.1007/s10832-012-9735-2  0.6
2012 Wu F, Wang YJ, Hong YL, Feng Y, Ruan KF. Progress in preparation and clinical application of traditional Chinese medicine placebo Chinese Journal of New Drugs. 21: 2161-2164.  0.68
2012 Cong WJ, Shen L, Ruan KF, Wang LY, Zhu YY, Feng Y. Mechanism study of rosiglitazone in the treatment of type 2 KKay diabetic mice Chinese Journal of New Drugs. 21: 2196-2201+2204.  0.68
2012 Li XH, Zhao LJ, Li MD, Feng Y, Xu DS, Ruan KF. Applications and characteristics of mathematical models to study compression process of pharmaceutical powder Chinese Journal of New Drugs. 21: 1362-1366.  0.68
2012 Wu F, Du RC, Hong YL, Wang YJ, Liang S, Feng Y, Ruan KF. Application of electronic tongue in the source identification of Aurantii Fructus Immaturus Chinese Pharmaceutical Journal. 47: 808-812.  0.68
2011 Wang ZJ, Lin X, Shen L, Feng Y, Xu DS, Ruan KF. [Pharmacokinetics of a long-circulating PEGylated Radix Ophiopogonis polysaccharide]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica. 46: 1257-61. PMID 22242461  0.68
2011 Lin X, Wang ZJ, Huang F, Liang S, Shen L, Feng Y, Ruan KF. Long-circulating delivery of bioactive polysaccharide from radix ophiopogonis by PEGylation. International Journal of Nanomedicine. 6: 2865-72. PMID 22131832 DOI: 10.2147/IJN.S26306  0.68
2011 Li J, Du R, Feng Y, Xu D, Ruan K. [Correlation of physical properties of herbal extracts and dry granulating process]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 36: 1606-9. PMID 22007543 DOI: 10.4268/cjcmm20111213  0.68
2011 Chen Y, Fujita T, Zhang D, Doan H, Pinkaew D, Liu Z, Wu J, Koide Y, Chiu A, Lin CC, Chang JY, Ruan KH, Fujise K. Physical and functional antagonism between tumor suppressor protein p53 and fortilin, an anti-apoptotic protein. The Journal of Biological Chemistry. 286: 32575-85. PMID 21795694 DOI: 10.1074/jbc.M110.217836  0.56
2011 Lin X, Wang ZJ, Wang S, Shen L, Feng Y, Ruan KF, Xu DS. Comparison of tissue distribution of a PEGylated Radix Ophiopogonis polysaccharide in mice with normal and ischemic myocardium. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 79: 621-6. PMID 21784151 DOI: 10.1016/j.ejpb.2011.07.002  0.68
2011 Xu J, Wang Y, Xu DS, Ruan KF, Feng Y, Wang S. Hypoglycemic effects of MDG-1, a polysaccharide derived from Ophiopogon japonicas, in the ob/ob mouse model of type 2 diabetes mellitus. International Journal of Biological Macromolecules. 49: 657-62. PMID 21756932 DOI: 10.1016/j.ijbiomac.2011.06.026  0.68
2011 Lin X, Chyi CW, Ruan KF, Feng Y, Heng PW. Development of potential novel cushioning agents for the compaction of coated multi-particulates by co-processing micronized lactose with polymers. European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft FüR Pharmazeutische Verfahrenstechnik E.V. 79: 406-15. PMID 21458566 DOI: 10.1016/j.ejpb.2011.03.024  0.68
2011 Ali YO, Escala W, Ruan K, Zhai RG. Assaying locomotor, learning, and memory deficits in Drosophila models of neurodegeneration. Journal of Visualized Experiments : Jove. PMID 21445036 DOI: 10.3791/2504  0.68
2011 Chillar AJ, Karimi P, Tang K, Ruan KH. An agonist sensitive, quick and simple cell-based signaling assay for determination of ligands mimicking prostaglandin E2 or E1 activity through subtype EP1 receptor: Suitable for high throughput screening. Bmc Complementary and Alternative Medicine. 11: 11. PMID 21299883 DOI: 10.1186/1472-6882-11-11  0.56
2011 Mohite A, Chillar A, So SP, Cervantes V, Ruan KH. Novel mechanism of the vascular protector prostacyclin: regulating microRNA expression. Biochemistry. 50: 1691-9. PMID 21250659 DOI: 10.1021/bi101654w  0.56
2011 Ruan CH, So SP, Ruan KH. Inducible COX-2 dominates over COX-1 in prostacyclin biosynthesis: mechanisms of COX-2 inhibitor risk to heart disease. Life Sciences. 88: 24-30. PMID 21035466 DOI: 10.1016/j.lfs.2010.10.017  0.56
2011 Chillar A, So SP, Ruan CH, Shelat H, Geng YJ, Ruan KH. A profile of NSAID-targeted arachidonic acid metabolisms in human embryonic stem cells (hESCs): implication of the negative effects of NSAIDs on heart tissue regeneration. International Journal of Cardiology. 150: 253-9. PMID 20451268 DOI: 10.1016/j.ijcard.2010.04.015  0.56
2011 Wei F, Liu YC, Ruan KB, Liu J, He ZM, Chen X, Chen MX. Fabrication of polymer solar cells by magnetic field disposal 2011 International Conference On Electric Information and Control Engineering, Iceice 2011 - Proceedings. 5918-5921. DOI: 10.1109/ICEICE.2011.5777228  0.6
2011 You YB, Hsiao TK, Chang BC, Tai MF, Hsu YY, Ku HC, Wei Z, Ruan KQ, Li XG. Anisotropic structural and magnetic properties of the field-aligned superconducting system SmFeAsO1-xFx (x = 0, 0.1, 0.2, 0.25 and 0.3) Journal of Physics: Conference Series. 273. DOI: 10.1088/1742-6596/273/1/012109  0.52
2011 Liu J, Huang J, Dai S, Zheng H, Li J, Shi F, Weng W, Ge Y, Deng J, Ruan K, Lin W. Thermal effect compensation method by using a optical media with variable temperature control in solid state laser Hongwai Yu Jiguang Gongcheng/Infrared and Laser Engineering. 40: 1900-1903.  0.6
2011 Wang S, Feng Y, Wang LY, Wang Y, Xu DS, Ruan KF. The effet of polysaccharide from Radix Astragali on cells survival against oxygen glucose deprivation and phosphorylation of Akt Pharmaceutical Biotechnology. 18: 288-290.  0.68
2011 Huang L, Liao Y, Ruan K, Wang L, Tang Y. Study on evaluation of reinjection ability of depleted well by using bittern reinjection well test Well Testing. 20: 27-31.  0.4
2010 Ruan CH, Dixon RA, Willerson JT, Ruan KH. Prostacyclin therapy for pulmonary arterial hypertension. Texas Heart Institute Journal / From the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital. 37: 391-9. PMID 20844610  0.56
2010 Chillar A, Wu J, Cervantes V, Ruan KH. Structural and functional analysis of the C-terminus of Galphaq in complex with the human thromboxane A2 receptor provides evidence of constitutive activity. Biochemistry. 49: 6365-74. PMID 20590159 DOI: 10.1021/bi100047n  0.96
2009 Ruan KH, Cervantes V, So SP. Engineering of a novel hybrid enzyme: an anti-inflammatory drug target with triple catalytic activities directly converting arachidonic acid into the inflammatory prostaglandin E2. Protein Engineering, Design & Selection : Peds. 22: 733-40. PMID 19850676 DOI: 10.1093/protein/gzp058  0.8
2009 Ruan KH, Cervantes V, Wu J. Ligand-specific conformation determines agonist activation and antagonist blockade in purified human thromboxane A2 receptor. Biochemistry. 48: 3157-65. PMID 19170518 DOI: 10.1021/bi801443g  0.96
2008 Ruan KH, So SP, Cervantes V, Wu H, Wijaya C, Jentzen RR. An active triple-catalytic hybrid enzyme engineered by linking cyclo-oxygenase isoform-1 to prostacyclin synthase that can constantly biosynthesize prostacyclin, the vascular protector. The Febs Journal. 275: 5820-9. PMID 19021758 DOI: 10.1111/j.1742-4658.2008.06703.x  0.8
2008 Ruan KH, So SP, Wu H, Cervantes V. Large-scale expression, purification, and characterization of an engineered prostacyclin-synthesizing enzyme with therapeutic potential. Archives of Biochemistry and Biophysics. 480: 41-50. PMID 18835243 DOI: 10.1016/  0.8
2008 Chillar A, Wu J, So SP, Ruan KH. Involvement of non-conserved residues important for PGE2 binding to the constrained EP3 eLP2 using NMR and site-directed mutagenesis. Febs Letters. 582: 2863-8. PMID 18652829 DOI: 10.1016/j.febslet.2008.07.018  0.96
2008 Ruan KH, Wijaya C, Cervantes V, Wu J. Characterization of the prostaglandin H2 mimic: binding to the purified human thromboxane A2 receptor in solution. Archives of Biochemistry and Biophysics. 477: 396-403. PMID 18590695 DOI: 10.1016/  0.96
2008 Ruan KH, Cervantes V, Wu J. A simple, quick, and high-yield preparation of the human thromboxane A2 receptor in full size for structural studies. Biochemistry. 47: 6819-26. PMID 18529068 DOI: 10.1021/bi702501g  0.96
2008 Ruan KH, Wu J, Cervantes V. Characterization of the substrate mimic bound to engineered prostacyclin synthase in solution using high-resolution NMR spectroscopy and mutagenesis: implication of the molecular mechanism in biosynthesis of prostacyclin. Biochemistry. 47: 680-8. PMID 18081314 DOI: 10.1021/bi701671q  0.96
2008 Wu J, Feng M, Ruan KH. Assembling NMR structures for the intracellular loops of the human thromboxane A2 receptor: implication of the G protein-coupling pocket. Archives of Biochemistry and Biophysics. 470: 73-82. PMID 18073117 DOI: 10.1016/  0.96
2008 Ni F, So SP, Cervantes V, Ruan KH. A profile of the residues in the second extracellular loop that are critical for ligand recognition of human prostacyclin receptor. The Febs Journal. 275: 128-37. PMID 18042246 DOI: 10.1111/j.1742-4658.2007.06183.x  0.8
2006 Ruan KH, Deng H, So SP. Engineering of a protein with cyclooxygenase and prostacyclin synthase activities that converts arachidonic acid to prostacyclin. Biochemistry. 45: 14003-11. PMID 17115695 DOI: 10.1021/bi0614277  0.8
2006 Zhang L, Bastepe M, Jüppner H, Ruan KH. Characterization of the molecular mechanisms of the coupling between intracellular loops of prostacyclin receptor with the C-terminal domain of the Galphas protein in human coronary artery smooth muscle cells. Archives of Biochemistry and Biophysics. 454: 80-8. PMID 16942748 DOI: 10.1016/  0.96
2006 Huang JC, Ruan CH, Tang K, Ruan KH. Prunella stica inhibits the proliferation but not the prostaglandin production of Ishikawa cells. Life Sciences. 79: 436-41. PMID 16481008 DOI: 10.1016/j.lfs.2006.01.018  0.72
2006 Zhang L, Wu J, Ruan KH. Solution structure of the first intracellular loop of prostacyclin receptor and implication of its interaction with the C-terminal segment of G alpha s protein. Biochemistry. 45: 1734-44. PMID 16460020 DOI: 10.1021/bi0515669  0.96
2005 Ruan KH, Wu J, Wang LH. Solution structure of a common substrate mimetic of cyclooxygenase-downstream synthases bound to an engineered thromboxane A2 synthase using a high-resolution NMR technique. Archives of Biochemistry and Biophysics. 444: 165-73. PMID 16297851 DOI: 10.1016/  0.96
2005 Ruan CH, Wu J, Ruan KH. A strategy using NMR peptide structures of thromboxane A2 receptor as templates to construct ligand-recognition pocket of prostacyclin receptor. Bmc Biochemistry. 6: 23. PMID 16271145 DOI: 10.1186/1471-2091-6-23  0.96
2005 Zhang L, Huang G, Wu J, Ruan KH. A profile of the residues in the first intracellular loop critical for Gs-mediated signaling of human prostacyclin receptor characterized by an integrative approach of NMR-experiment and mutagenesis. Biochemistry. 44: 11389-401. PMID 16114876 DOI: 10.1021/bi050483p  0.96
2005 Ruan KH, Deng H, Wu J, So SP. The N-terminal membrane anchor domain of the membrane-bound prostacyclin synthase involved in the substrate presentation of the coupling reaction with cyclooxygenase. Archives of Biochemistry and Biophysics. 435: 372-81. PMID 15708381 DOI: 10.1016/  0.96
2004 Ruan KH, Wu J, So SP, Jenkins LA, Ruan CH. NMR structure of the thromboxane A2 receptor ligand recognition pocket. European Journal of Biochemistry / Febs. 271: 3006-16. PMID 15233797 DOI: 10.1111/j.1432-1033.2004.04232.x  0.96
2004 Geng L, Wu J, So SP, Huang G, Ruan KH. Structural and functional characterization of the first intracellular loop of human thromboxane A2 receptor. Archives of Biochemistry and Biophysics. 423: 253-65. PMID 15001390 DOI: 10.1016/  0.96
2003 Ruan KH, Wu J, So SP, Jenkins LA. Evidence of the residues involved in ligand recognition in the second extracellular loop of the prostacyclin receptor characterized by high resolution 2D NMR techniques. Archives of Biochemistry and Biophysics. 418: 25-33. PMID 13679079  0.96
2003 Wu J, So SP, Ruan KH. Solution structure of the third extracellular loop of human thromboxane A2 receptor. Archives of Biochemistry and Biophysics. 414: 287-93. PMID 12781781  0.96
2003 Deng H, Wu J, So SP, Ruan KH. Identification of the residues in the helix F/G loop important to catalytic function of membrane-bound prostacyclin synthase. Biochemistry. 42: 5609-17. PMID 12741817 DOI: 10.1021/bi026749z  0.96
2003 Wu J, So SP, Ruan KH. Determination of the membrane contact residues and solution structure of the helix F/G loop of prostaglandin I2 synthase. Archives of Biochemistry and Biophysics. 411: 27-35. PMID 12590920  0.96
2003 So SP, Wu J, Huang G, Huang A, Li D, Ruan KH. Identification of residues important for ligand binding of thromboxane A2 receptor in the second extracellular loop using the NMR experiment-guided mutagenesis approach. The Journal of Biological Chemistry. 278: 10922-7. PMID 12551898 DOI: 10.1074/jbc.M209337200  0.96
2002 Arbab F, Goldsby J, Matijevic-Aleksic N, Huang G, Ruan KH, Huang JC. Prostacyclin is an autocrine regulator in the contraction of oviductal smooth muscle. Human Reproduction (Oxford, England). 17: 3053-9. PMID 12456602  0.72
2002 Ruan KH, So SP, Zheng W, Wu J, Li D, Kung J. Solution structure and topology of the N-terminal membrane anchor domain of a microsomal cytochrome P450: prostaglandin I2 synthase. The Biochemical Journal. 368: 721-8. PMID 12193162 DOI: 10.1042/BJ20021001  0.96
2002 Deng WG, Saunders M, Gilroy D, He XZ, Yeh H, Zhu Y, Shtivelband MI, Ruan KH, Wu KK. Purification and characterization of a cyclooxygenase-2 and angiogenesis suppressing factor produced by human fibroblasts. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1286-8. PMID 12060668 DOI: 10.1096/fj.01-0844fje  0.68
2002 Deng H, Huang A, So SP, Lin YZ, Ruan KH. Substrate access channel topology in membrane-bound prostacyclin synthase. The Biochemical Journal. 362: 545-51. PMID 11879180  0.8
2001 Ruan KH, So SP, Wu J, Li D, Huang A, Kung J. Solution structure of the second extracellular loop of human thromboxane A2 receptor. Biochemistry. 40: 275-80. PMID 11141080  0.96
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