Lisa C. Rohan - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Pharmacy, Pharmacology, Pharmaceutical Chemistry
Website:
http://www.pharmacy.pitt.edu/directory/profile.php?profile=106

97 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Li J, Regev G, Patel SK, Patton D, Sweeney Y, Graebing P, Grab S, Wang L, Sant V, Rohan LC. Rational Design of a Multipurpose Bioadhesive Vaginal Film for Co-Delivery of Dapivirine and Levonorgestrel. Pharmaceutics. 12. PMID 31861267 DOI: 10.3390/pharmaceutics12010001  0.68
2019 Günaydın G, Edfeldt G, Garber DA, Asghar M, Noȅl-Romas L, Burgener A, Wählby C, Wang L, Rohan LC, Guenthner P, Mitchell J, Matoba N, McNicholl JM, Palmer KE, Tjernlund A, et al. Impact of Q-Griffithsin anti-HIV microbicide gel in non-human primates: In situ analyses of epithelial and immune cell markers in rectal mucosa. Scientific Reports. 9: 18120. PMID 31792342 DOI: 10.1038/s41598-019-54493-4  0.68
2019 McKinley D, Patel SK, Regev G, Rohan LC, Akil A. Delineating the Effects of Hot-Melt Extrusion on the Performance of a Polymeric Film using Artificial Neural Networks and an Evolutionary Algorithm. International Journal of Pharmaceutics. 118715. PMID 31560958 DOI: 10.1016/j.ijpharm.2019.118715  0.32
2019 Gong T, Patel SK, Parniak MA, Ballou B, Rohan LC. Nanocrystal Formulation Improves Vaginal Delivery of CSIC for HIV Prevention. Aaps Pharmscitech. 20: 286. PMID 31410664 DOI: 10.1208/s12249-019-1503-z  0.4
2019 Regev G, Patel SK, Moncla BJ, Twist J, Devlin B, Rohan LC. Novel Application of Hot Melt Extrusion for the Manufacturing of Vaginal Films Containing Microbicide Candidate Dapivirine. Aaps Pharmscitech. 20: 239. PMID 31243640 DOI: 10.1208/s12249-019-1442-8  0.6
2019 Yang H, Li J, Patel SK, Palmer KE, Devlin B, Rohan LC. Design of Poly(lactic--glycolic Acid) (PLGA) Nanoparticles for Vaginal Co-Delivery of Griffithsin and Dapivirine and Their Synergistic Effect for HIV Prophylaxis. Pharmaceutics. 11. PMID 30995761 DOI: 10.3390/pharmaceutics11040184  0.68
2018 Koppolu S, Wang L, Mathur A, Nigam JA, Dezzutti CS, Isaacs C, Meyn L, Bunge KE, Moncla BJ, Hillier SL, Rohan LC, Mahal LK. Vaginal Product Formulation Alters the Innate Anti-viral Activity and Glycome of Cervicovaginal Fluids with Implications for Viral Susceptibility. Acs Infectious Diseases. PMID 30183260 DOI: 10.1021/acsinfecdis.8b00157  0.68
2018 Bunge KE, Dezzutti CS, Hendrix CW, Marzinke MA, Spiegel HML, Moncla BJ, Schwartz JL, Meyn LA, Richardson-Harman N, Rohan LC, Hillier SL. FAME-04: A Phase 1 trial to assess the safety, acceptability, pharmacokinetics and pharmacodynamics of film and gel formulations of tenofovir. Journal of the International Aids Society. 21: e25156. PMID 30101439 DOI: 10.1002/jia2.25156  0.44
2018 Hughes SM, Ferre AL, Yandura SE, Shetler C, Baker CAR, Calienes F, Levy CN, Astronomo RD, Shu Z, Lentz GM, Fialkow M, Kirby AC, McElrath MJ, Sinclair E, Rohan LC, et al. Cryopreservation of human mucosal tissues. Plos One. 13: e0200653. PMID 30059507 DOI: 10.1371/journal.pone.0200653  0.44
2018 Hillier SL, Cummins JE, Rohan LC. Charlene Susan Dezzutti (1964-2018) Virologist with a Passion for HIV Prevention. Aids Research and Human Retroviruses. 34: 475-476. PMID 29888975 DOI: 10.1089/aid.2018.29003.hil  0.44
2018 Feturi FG, Weinstock M, Zhao W, Zhang W, Schnider JT, Erbas VE, Oksuz S, Plock JA, Rohan L, Spiess AM, Ferreira LM, Solari MG, Venkataramanan R, Gorantla VS. Mycophenolic Acid for Topical Immunosuppression in Vascularized Composite Allotransplantation: Optimizing Formulation and Preliminary Evaluation of Bioavailability and Pharmacokinetics. Frontiers in Surgery. 5: 20. PMID 29868602 DOI: 10.3389/fsurg.2018.00020  0.4
2018 Girard L, Birse K, Holm JB, Gajer P, Humphrys MS, Garber D, Guenthner P, Noël-Romas L, Abou M, McCorrister S, Westmacott G, Wang L, Rohan LC, Matoba N, McNicholl J, et al. Impact of the griffithsin anti-HIV microbicide and placebo gels on the rectal mucosal proteome and microbiome in non-human primates. Scientific Reports. 8: 8059. PMID 29795295 DOI: 10.1038/s41598-018-26313-8  0.68
2017 Xiao P, Gumber S, Marzinke MA, Date AA, Hoang T, Hanes J, Ensign LM, Wang L, Rohan L, Fuchs EJ, Hendrix C, Villinger F. Hypo-osmolar formulation of TFV enema promotes uptake and metabolism of TFV in tissues and leading to prevention of SHIV/SIV infection. Antimicrobial Agents and Chemotherapy. PMID 29084755 DOI: 10.1128/AAC.01644-17  0.68
2017 Gong T, Zhang W, Parniak MA, Graebing PW, Moncla B, Gupta P, Empey KM, Rohan LC. Preformulation and Vaginal Film Formulation Development of Microbicide Drug Candidate CSIC for HIV prevention. Journal of Pharmaceutical Innovation. 12: 142-154. PMID 28983328 DOI: 10.1007/s12247-017-9274-0  0.4
2017 M Guthrie K, Rohan L, Rosen RK, Vargas SE, Ham AS, Friend D, Katz D, Shaw JG, Kojic EM, Buckheit KW, Buckheit RW. Vaginal Film for Prevention of HIV: Using Visual and Tactile Evaluations among Potential Users to Inform Product Design. Pharmaceutical Development and Technology. 1-12. PMID 28592183 DOI: 10.1080/10837450.2017.1339085  0.44
2016 Hu M, Zhou T, Pearlman AP, Paton DL, Rohan LC. Comparative Expression Analysis of Cytochrome P450 1A1, Cytochrome P450 1B1 and Nuclear Receptors in the Female Genital and Colorectal Tissues of Human and Pigtailed Macaque. Baoj Pharmaceutical Sciences. 2. PMID 29276805  0.36
2016 Hu M, Zhou T, Dezzutti CS, Rohan LC. The Effect of Commonly Used Excipients on the Epithelial Integrity of Human Cervicovaginal Tissue. Aids Research and Human Retroviruses. PMID 27611224 DOI: 10.1089/AID.2016.0014  0.88
2016 Fan MD, Kramzer LF, Hillier SL, Chang JC, Meyn LA, Rohan LC. Preferred Physical Characteristics of Vaginal Film Microbicides for HIV Prevention in Pittsburgh Women. Archives of Sexual Behavior. PMID 27571742 DOI: 10.1007/s10508-016-0816-1  0.88
2016 Salie ZL, Kirby KA, Michailidis E, Marchand B, Singh K, Rohan LC, Kodama EN, Mitsuya H, Parniak MA, Sarafianos SG. Structural basis of HIV inhibition by translocation-defective RT inhibitor 4'-ethynyl-2-fluoro-2'-deoxyadenosine (EFdA). Proceedings of the National Academy of Sciences of the United States of America. PMID 27489345 DOI: 10.1073/pnas.1605223113  0.4
2016 Zhou T, Hu M, Pearlman A, Rohan LC. Expression, Regulation, and Function of Drug Transporters in Cervicovaginal Tissues of a Mouse Model Used for Microbicide Testing. Biochemical Pharmacology. PMID 27453435 DOI: 10.1016/j.bcp.2016.07.009  0.88
2016 Dezzutti CS, Richardson-Harman N, Rohan LC, Marzinke MA, Hoesley CJ, Panther L, Johnson S, Nuttall JP, Nel A, Chen BA. Pharmacodynamic correlations using fresh and cryopreserved tissue following use of vaginal rings containing dapivirine and/or maraviroc in a randomized, placebo controlled trial. Medicine. 95: e4174. PMID 27428211 DOI: 10.1097/MD.0000000000004174  0.44
2016 Salie ZL, Kirby KA, Michailidis E, Marchand B, Singh K, Rohan LC, Kodama EN, Mitsuya H, Parniak MA, Sarafianos SG. Structural basis of HIV inhibition by translocationdefective RT inhibitor 4′-ethynyl-2-fluoro-2′- deoxyadenosine (EFdA) Proceedings of the National Academy of Sciences of the United States of America. 113: 9274-9279. DOI: 10.1073/pnas.1605223113/-/DCSupplemental  0.4
2015 Bunge KE, Dezzutti CS, Rohan LC, Hendrix CW, Marzinke MA, Richardson-Harman N, Moncla BJ, Devlin B, Meyn LA, Spiegel HM, Hillier SL. A Phase 1 trial to assess the safety, acceptability, pharmacokinetics and pharmacodynamics of a novel dapivirine vaginal film. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 26565716 DOI: 10.1097/QAI.0000000000000897  0.6
2015 Hu M, Patel SK, Zhou T, Rohan LC. Drug transporters in tissues and cells relevant to sexual transmission of HIV: Implications for drug delivery. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 26278511 DOI: 10.1016/j.jconrel.2015.08.018  0.88
2015 Dezzutti CS, Yandura S, Wang L, Moncla B, Teeple EA, Devlin B, Nuttall J, Brown ER, Rohan LC. Pharmacodynamic Activity of Dapivirine and Maraviroc Single Entity and Combination Topical Gels for HIV-1 Prevention. Pharmaceutical Research. PMID 26078001 DOI: 10.1007/s11095-015-1738-7  0.88
2015 Dobard CW, Taylor A, Sharma S, Anderson PL, Bushman LR, Chuong D, Pau CP, Hanson D, Wang L, Garcia-Lerma JG, McGowan I, Rohan L, Heneine W. Protection Against Rectal Chimeric Simian/Human Immunodeficiency Virus Transmission in Macaques by Rectal-Specific Gel Formulations of Maraviroc and Tenofovir. The Journal of Infectious Diseases. PMID 26071566 DOI: 10.1093/infdis/jiv334  0.68
2015 Kramzer LF, Cohen J, Schubert J, Dezzutti CS, Moncla BJ, Friend D, Rohan LC. Assessing the potential of the Woman's Condom for vaginal drug delivery. Contraception. 92: 254-60. PMID 25998936 DOI: 10.1016/j.contraception.2015.05.005  0.88
2015 Mcgowan I, Cranston RD, Duffill K, Siegel A, Engstrom JC, Nikiforov A, Jacobson C, Rehman KK, Elliott J, Khanukhova E, Abebe K, Mauck C, Spiegel HM, Dezzutti CS, Rohan LC, et al. A Phase 1 Randomized, Open Label, Rectal Safety, Acceptability, Pharmacokinetic, and Pharmacodynamic Study of Three Formulations of Tenofovir 1% Gel (the CHARM-01 Study). Plos One. 10: e0125363. PMID 25942472 DOI: 10.1371/journal.pone.0125363  0.44
2015 Holt JD, Cameron D, Dias N, Holding J, Muntendam A, Oostebring F, Dreier P, Rohan L, Nuttall J. The Sheep as a Model of Preclinical Safety and Pharmacokinetic Evaluations of Candidate Microbicides. Antimicrobial Agents and Chemotherapy. 59: 3761-70. PMID 25845860 DOI: 10.1128/AAC.04954-14  0.88
2015 Zhang W, Hu M, Shi Y, Gong T, Dezzutti CS, Moncla B, Sarafianos SG, Parniak MA, Rohan LC. Vaginal Microbicide Film Combinations of Two Reverse Transcriptase Inhibitors, EFdA and CSIC, for the Prevention of HIV-1 Sexual Transmission. Pharmaceutical Research. PMID 25794967 DOI: 10.1007/s11095-015-1678-2  0.88
2015 Akil A, Agashe H, Dezzutti CS, Moncla BJ, Hillier SL, Devlin B, Shi Y, Uranker K, Rohan LC. Formulation and characterization of polymeric films containing combinations of antiretrovirals (ARVs) for HIV prevention. Pharmaceutical Research. 32: 458-68. PMID 25079391 DOI: 10.1007/s11095-014-1474-4  0.88
2015 Mcgowan I, Cranston RD, Duffill K, Siegel A, Engstrom JC, Nikiforov A, Jacobson C, Rehman KK, Elliott J, Khanukhova E, Abebe K, Mauck C, Spiegel HML, Dezzutti CS, Rohan LC, et al. A phase 1 randomized, open label, rectal safety, acceptability, pharmacokinetic, and pharmacodynamic study of three formulations of tenofovir 1% Gel (the CHARM-01 study) Plos One. 10. DOI: 10.1371/journal.pone.0125363  0.88
2015 Mukundan S, Sant V, Goenka S, Franks J, Rohan LC, Sant S. Nanofibrous composite scaffolds of poly(ester amides) with tunable physicochemical and degradation properties European Polymer Journal. 68: 21-35. DOI: 10.1016/j.eurpolymj.2015.04.026  0.88
2014 Dezzutti CS, Russo J, Wang L, Abebe KZ, Li J, Friend DR, McGowan IM, Rohan LC. Development of HIV-1 rectal-specific microbicides and colonic tissue evaluation. Plos One. 9: e102585. PMID 25025306 DOI: 10.1371/journal.pone.0102585  0.88
2014 Michailidis E, Huber AD, Ryan EM, Ong YT, Leslie MD, Matzek KB, Singh K, Marchand B, Hagedorn AN, Kirby KA, Rohan LC, Kodama EN, Mitsuya H, Parniak MA, Sarafianos SG. 4'-Ethynyl-2-fluoro-2'-deoxyadenosine (EFdA) inhibits HIV-1 reverse transcriptase with multiple mechanisms. The Journal of Biological Chemistry. 289: 24533-48. PMID 24970894 DOI: 10.1074/jbc.M114.562694  0.88
2014 Carballo-Diéguez A, Giguere R, Dolezal C, Bauermeister J, Leu CS, Valladares J, Rohan LC, Anton PA, Cranston RD, Febo I, Mayer K, McGowan I. Rectal-specific microbicide applicator: evaluation and comparison with a vaginal applicator used rectally. Aids and Behavior. 18: 1734-45. PMID 24858481 DOI: 10.1007/s10461-014-0793-0  0.88
2014 Zhou T, Hu M, Pearlman A, Patton D, Rohan L. Expression and localization of p-glycoprotein, multidrug resistance protein 4, and breast cancer resistance protein in the female lower genital tract of human and pigtailed macaque. Aids Research and Human Retroviruses. 30: 1106-16. PMID 24803409 DOI: 10.1089/AID.2013.0281  0.88
2014 Rinehart M, Grab S, Rohan L, Katz D, Wax A. Analysis of vaginal microbicide film hydration kinetics by quantitative imaging refractometry. Plos One. 9: e95005. PMID 24736376 DOI: 10.1371/journal.pone.0095005  0.88
2014 Akil A, Devlin B, Cost M, Rohan LC. Increased Dapivirine tissue accumulation through vaginal film codelivery of dapivirine and Tenofovir. Molecular Pharmaceutics. 11: 1533-41. PMID 24693866 DOI: 10.1021/mp4007024  0.88
2014 Zhang W, Parniak MA, Sarafianos SG, Empey PE, Rohan LC. In vitro transport characteristics of EFdA, a novel nucleoside reverse transcriptase inhibitor using Caco-2 and MDCKII cell monolayers. European Journal of Pharmacology. 732: 86-95. PMID 24690257 DOI: 10.1016/j.ejphar.2014.03.022  0.88
2014 Chappell CA, Rohan LC, Moncla BJ, Wang L, Meyn LA, Bunge K, Hillier SL. The effects of reproductive hormones on the physical properties of cervicovaginal fluid. American Journal of Obstetrics and Gynecology. 211: 226.e1-7. PMID 24662718 DOI: 10.1016/j.ajog.2014.03.041  0.88
2014 Zhang W, Parniak MA, Sarafianos SG, Cost MR, Rohan LC. Development of a vaginal delivery film containing EFdA, a novel anti-HIV nucleoside reverse transcriptase inhibitor. International Journal of Pharmaceutics. 461: 203-13. PMID 24333452 DOI: 10.1016/j.ijpharm.2013.11.056  0.88
2014 Rohan LC, Devlin B, Yang H. Microbicide dosage forms. Current Topics in Microbiology and Immunology. 383: 27-54. PMID 24220751 DOI: 10.1007/82_2013_357  0.88
2014 Zhang W, Parniak MA, Mitsuya H, Sarafianos SG, Graebing PW, Rohan LC. Preformulation studies of EFdA, a novel nucleoside reverse transcriptase inhibitor for HIV prevention. Drug Development and Industrial Pharmacy. 40: 1101-11. PMID 23841536 DOI: 10.3109/03639045.2013.809535  0.88
2013 Rohan LC, Yang H, Wang L. Rectal pre-exposure prophylaxis (PrEP). Antiviral Research. 100: S17-24. PMID 24188705 DOI: 10.1016/j.antiviral.2013.09.023  0.88
2013 Hachiya A, Reeve AB, Marchand B, Michailidis E, Ong YT, Kirby KA, Leslie MD, Oka S, Kodama EN, Rohan LC, Mitsuya H, Parniak MA, Sarafianos SG. Evaluation of combinations of 4'-ethynyl-2-fluoro-2'-deoxyadenosine with clinically used antiretroviral drugs. Antimicrobial Agents and Chemotherapy. PMID 23796932 DOI: 10.1128/AAC.00283-13  0.88
2013 Obitte NC, Rohan LC, Adeyeye CM, Parniak MA, Esimone CO. The utility of self-emulsifying oil formulation to improve the poor solubility of the anti HIV drug CSIC. Aids Research and Therapy. 10: 14. PMID 23721408 DOI: 10.1186/1742-6405-10-14  0.88
2013 Zhou T, Hu M, Cost M, Poloyac S, Rohan L. Short communication: expression of transporters and metabolizing enzymes in the female lower genital tract: implications for microbicide research. Aids Research and Human Retroviruses. 29: 1496-503. PMID 23607746 DOI: 10.1089/aid.2013.0032  0.36
2013 Tasoglu S, Rohan LC, Katz DF, Szeri AJ. Transient swelling, spreading, and drug delivery by a dissolved anti-HIV microbicide-bearing film. Physics of Fluids (Woodbury, N.Y. : 1994). 25: 31901. PMID 23554549 DOI: 10.1063/1.4793598  0.88
2013 Nixon B, Stefanidou M, Mesquita PM, Fakioglu E, Segarra T, Rohan L, Halford W, Palmer KE, Herold BC. Griffithsin protects mice from genital herpes by preventing cell-to-cell spread. Journal of Virology. 87: 6257-69. PMID 23536670 DOI: 10.1128/JVI.00012-13  0.88
2013 Wood MP, Cole AL, Ruchala P, Waring AJ, Rohan LC, Marx P, Tarwater PM, Gupta P, Cole AM. A compensatory mutation provides resistance to disparate HIV fusion inhibitor peptides and enhances membrane fusion. Plos One. 8: e55478. PMID 23393582 DOI: 10.1371/journal.pone.0055478  0.88
2013 Gao X, Huang Y, Makhov AM, Epperly M, Lu J, Grab S, Zhang P, Rohan L, Xie XQ, Wipf P, Greenberger J, Li S. Nanoassembly of surfactants with interfacial drug-interactive motifs as tailor-designed drug carriers. Molecular Pharmaceutics. 10: 187-98. PMID 23244299 DOI: 10.1021/mp300319m  0.88
2013 Eade CR, Cole AL, Diaz C, Rohan LC, Parniak MA, Marx P, Tarwater PM, Gupta P, Cole AM. The anti-HIV microbicide candidate RC-101 inhibits pathogenic vaginal bacteria without harming endogenous flora or mucosa. American Journal of Reproductive Immunology (New York, N.Y. : 1989). 69: 150-8. PMID 23167830 DOI: 10.1111/aji.12036  0.88
2013 Gupta P, Lackman-Smith C, Snyder B, Ratner D, Rohan LC, Patton D, Ramratnam B, Cole AM. Antiviral activity of retrocyclin RC-101, a candidate microbicide against cell-associated HIV-1. Aids Research and Human Retroviruses. 29: 391-6. PMID 22924614 DOI: 10.1089/AID.2012.0135  0.88
2012 Yang H, Parniak MA, Hillier SL, Rohan LC. A thermodynamic study of the cyclodextrin-UC781 inclusion complex using a HPLC method. Journal of Inclusion Phenomena and Macrocyclic Chemistry. 72: 459-465. PMID 26097403 DOI: 10.1007/s10847-011-0019-2  0.88
2012 Dezzutti CS, Brown ER, Moncla B, Russo J, Cost M, Wang L, Uranker K, Kunjara Na Ayudhya RP, Pryke K, Pickett J, Leblanc MA, Rohan LC. Is wetter better? An evaluation of over-the-counter personal lubricants for safety and anti-HIV-1 activity. Plos One. 7: e48328. PMID 23144863 DOI: 10.1371/journal.pone.0048328  0.88
2012 Huang Y, Lu J, Gao X, Li J, Zhao W, Sun M, Stolz DB, Venkataramanan R, Rohan LC, Li S. PEG-derivatized embelin as a dual functional carrier for the delivery of paclitaxel. Bioconjugate Chemistry. 23: 1443-51. PMID 22681537 DOI: 10.1021/bc3000468  0.88
2012 Gupta P, Ratner D, Ding M, Patterson B, Rohan LC, Reinhart TA, Ayyavoo V, Huang X, Patton DL, Ramratnam B, Cole AM. Retrocyclin RC-101 blocks HIV-1 transmission across cervical mucosa in an organ culture. Journal of Acquired Immune Deficiency Syndromes (1999). 60: 455-61. PMID 22592582 DOI: 10.1097/QAI.0b013e318258b420  0.88
2012 Dezzutti CS, Rohan LC, Wang L, Uranker K, Shetler C, Cost M, Lynam JD, Friend D. Reformulated tenofovir gel for use as a dual compartment microbicide. The Journal of Antimicrobial Chemotherapy. 67: 2139-42. PMID 22581908 DOI: 10.1093/jac/dks173  0.88
2012 Cost M, Dezzutti CS, Clark MR, Friend DR, Akil A, Rohan LC. Characterization of UC781-tenofovir combination gel products for HIV-1 infection prevention in an ex vivo ectocervical model. Antimicrobial Agents and Chemotherapy. 56: 3058-66. PMID 22430977 DOI: 10.1128/AAC.06284-11  0.88
2012 Ham AS, Rohan LC, Boczar A, Yang L, W Buckheit K, Buckheit RW. Vaginal film drug delivery of the pyrimidinedione IQP-0528 for the prevention of HIV infection. Pharmaceutical Research. 29: 1897-907. PMID 22392331 DOI: 10.1007/s11095-012-0715-7  0.88
2012 Moncla BJ, Pryke K, Rohan LC, Yang H. Testing of viscous anti-HIV microbicides using Lactobacillus. Journal of Microbiological Methods. 88: 292-6. PMID 22226641 DOI: 10.1016/j.mimet.2011.12.013  0.88
2012 Wang L, Sassi AB, Patton D, Isaacs C, Moncla BJ, Gupta P, Rohan LC. Development of a liposome microbicide formulation for vaginal delivery of octylglycerol for HIV prevention. Drug Development and Industrial Pharmacy. 38: 995-1007. PMID 22149387 DOI: 10.3109/03639045.2011.637048  0.88
2011 Akil A, Parniak MA, Dezzuitti CS, Moncla BJ, Cost MR, Li M, Rohan LC. Development and Characterization of a Vaginal Film Containing Dapivirine, a Non- nucleoside Reverse Transcriptase Inhibitor (NNRTI), for prevention of HIV-1 sexual transmission. Drug Delivery and Translational Research. 1: 209-222. PMID 22708075 DOI: 10.1007/s13346-011-0022-6  0.88
2011 Ferguson LM, Rohan LC. The importance of the vaginal delivery route for antiretrovirals in HIV prevention. Therapeutic Delivery. 2: 1535-50. PMID 22468220 DOI: 10.4155/tde.11.126  0.88
2011 Rinehart MT, Drake TK, Robles FE, Rohan LC, Katz D, Wax A. Time-resolved imaging refractometry of microbicidal films using quantitative phase microscopy. Journal of Biomedical Optics. 16: 120510. PMID 22191912 DOI: 10.1117/1.3665439  0.88
2011 Isaacs CE, Xu W, Merz G, Hillier S, Rohan L, Wen GY. Digallate dimers of (-)-epigallocatechin gallate inactivate herpes simplex virus. Antimicrobial Agents and Chemotherapy. 55: 5646-53. PMID 21947401 DOI: 10.1128/AAC.05531-11  0.88
2011 Li M, Patton DL, Cosgrove-Sweeney Y, Ratner D, Rohan LC, Cole AM, Tarwater PM, Gupta P, Ramratnam B. Incorporation of the HIV-1 microbicide cyanovirin-N in a food product. Journal of Acquired Immune Deficiency Syndromes (1999). 58: 379-84. PMID 21926631 DOI: 10.1097/QAI.0b013e31823643fe  0.88
2011 Mahalingam A, Jay JI, Langheinrich K, Shukair S, McRaven MD, Rohan LC, Herold BC, Hope TJ, Kiser PF. Inhibition of the transport of HIV in vitro using a pH-responsive synthetic mucin-like polymer system. Biomaterials. 32: 8343-55. PMID 21875751 DOI: 10.1016/j.biomaterials.2011.05.001  0.88
2011 Sassi AB, Bunge KE, Hood BL, Conrads TP, Cole AM, Gupta P, Rohan LC. Preformulation and stability in biological fluids of the retrocyclin RC-101, a potential anti-HIV topical microbicide. Aids Research and Therapy. 8: 27. PMID 21801426 DOI: 10.1186/1742-6405-8-27  0.88
2011 Poloyac SM, Empey KM, Rohan LC, Skledar SJ, Empey PE, Nolin TD, Bies RR, Gibbs RB, Folan M, Kroboth PD. Core competencies for research training in the clinical pharmaceutical sciences. American Journal of Pharmaceutical Education. 75: 27. PMID 21519417  0.88
2011 Wang L, Schnaare RL, Dezzutti C, Anton PA, Rohan LC. Rectal microbicides: clinically relevant approach to the design of rectal specific placebo formulations. Aids Research and Therapy. 8: 12. PMID 21385339 DOI: 10.1186/1742-6405-8-12  0.88
2011 Sassi AB, Cost MR, Cole AL, Cole AM, Patton DL, Gupta P, Rohan LC. Formulation development of retrocyclin 1 analog RC-101 as an anti-HIV vaginal microbicide product. Antimicrobial Agents and Chemotherapy. 55: 2282-9. PMID 21321138 DOI: 10.1128/AAC.01190-10  0.88
2011 Mahalingam A, Simmons AP, Ugaonkar SR, Watson KM, Dezzutti CS, Rohan LC, Buckheit RW, Kiser PF. Vaginal microbicide gel for delivery of IQP-0528, a pyrimidinedione analog with a dual mechanism of action against HIV-1. Antimicrobial Agents and Chemotherapy. 55: 1650-60. PMID 21245437 DOI: 10.1128/AAC.01368-10  0.88
2010 Cole AM, Patton DL, Rohan LC, Cole AL, Cosgrove-Sweeney Y, Rogers NA, Ratner D, Sassi AB, Lackman-Smith C, Tarwater P, Ramratnam B, Ruchala P, Lehrer RI, Waring AJ, Gupta P. The formulated microbicide RC-101 was safe and antivirally active following intravaginal application in pigtailed macaques. Plos One. 5: e15111. PMID 21124745 DOI: 10.1371/journal.pone.0015111  0.88
2010 Garg S, Goldman D, Krumme M, Rohan LC, Smoot S, Friend DR. Advances in development, scale-up and manufacturing of microbicide gels, films, and tablets. Antiviral Research. 88: S19-29. PMID 21109064 DOI: 10.1016/j.antiviral.2010.09.010  0.88
2010 Rohan LC, Moncla BJ, Kunjara Na Ayudhya RP, Cost M, Huang Y, Gai F, Billitto N, Lynam JD, Pryke K, Graebing P, Hopkins N, Rooney JF, Friend D, Dezzutti CS. In vitro and ex vivo testing of tenofovir shows it is effective as an HIV-1 microbicide. Plos One. 5: e9310. PMID 20174579 DOI: 10.1371/journal.pone.0009310  0.88
2010 Mallipeddi R, Rohan LC. Nanoparticle-based vaginal drug delivery systems for HIV prevention. Expert Opinion On Drug Delivery. 7: 37-48. PMID 20017659 DOI: 10.1517/17425240903338055  0.88
2010 Mallipeddi R, Rohan LC. Progress in antiretroviral drug delivery using nanotechnology International Journal of Nanomedicine. 5: 533-547.  0.88
2009 Rohan LC, Sassi AB. Vaginal drug delivery systems for HIV prevention. The Aaps Journal. 11: 78-87. PMID 19194802 DOI: 10.1208/s12248-009-9082-7  0.88
2009 Ham AS, Cost MR, Sassi AB, Dezzutti CS, Rohan LC. Targeted delivery of PSC-RANTES for HIV-1 prevention using biodegradable nanoparticles. Pharmaceutical Research. 26: 502-11. PMID 19002569 DOI: 10.1007/s11095-008-9765-2  0.88
2008 Romano J, Malcolm RK, Garg S, Rohan LC, Kaptur PE. Microbicide delivery: formulation technologies and strategies. Current Opinion in Hiv and Aids. 3: 558-66. PMID 19373022 DOI: 10.1097/COH.0b013e328305b96e  0.88
2008 Yang H, Parniak MA, Isaacs CE, Hillier SL, Rohan LC. Characterization of cyclodextrin inclusion complexes of the anti-HIV non-nucleoside reverse transcriptase inhibitor UC781. The Aaps Journal. 10: 606-13. PMID 19089644 DOI: 10.1208/s12248-008-9070-3  0.88
2008 Mu Y, Klamerus MM, Miller TM, Rohan LC, Graham SH, Poloyac SM. Intravenous formulation of N-hydroxy-N'-(4-n-butyl-2-methylphenyl)formamidine (HET0016) for inhibition of rat brain 20-hydroxyeicosatetraenoic acid formation. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 36: 2324-30. PMID 18725506 DOI: 10.1124/dmd.108.023150  0.88
2008 Fader AN, Edwards RP, Cost M, Kanbour-Shakir A, Kelley JL, Schwartz B, Sukumvanich P, Comerci J, Sumkin J, Elishaev E, Rohan LC. Sentinel lymph node biopsy in early-stage cervical cancer: utility of intraoperative versus postoperative assessment. Gynecologic Oncology. 111: 13-7. PMID 18684499 DOI: 10.1016/j.ygyno.2008.06.009  0.88
2008 Isaacs CE, Wen GY, Xu W, Jia JH, Rohan L, Corbo C, Di Maggio V, Jenkins EC, Hillier S. Epigallocatechin gallate inactivates clinical isolates of herpes simplex virus. Antimicrobial Agents and Chemotherapy. 52: 962-70. PMID 18195068 DOI: 10.1128/AAC.00825-07  0.88
2008 Sassi AB, Isaacs CE, Moncla BJ, Gupta P, Hillier SL, Rohan LC. Effects of physiological fluids on physical-chemical characteristics and activity of topical vaginal microbicide products. Journal of Pharmaceutical Sciences. 97: 3123-39. PMID 17922539 DOI: 10.1002/jps.21192  0.88
2007 Rohan LC, Hillier SL, Dezzutti CS. Preventing the sexual transmission of HIV-1 with topical microbicides: another piece of the equation. The Journal of Infectious Diseases. 196: 1285-7. PMID 17922391 DOI: 10.1086/522610  0.88
2007 Patton DL, Cosgrove Sweeney YT, Balkus JE, Rohan LC, Moncla BJ, Parniak MA, Hillier SL. Preclinical safety assessments of UC781 anti-human immunodeficiency virus topical microbicide formulations Antimicrobial Agents and Chemotherapy. 51: 1608-1615. PMID 17353240 DOI: 10.1128/AAC.00984-06  0.88
2006 Gupta P, Ratner D, Patterson BK, Kulka K, Rohan LC, Parniak MA, Isaacs CE, Hillier S. Use of frozen-thawed cervical tissues in the organ culture system to measure anti-HIV activities of candidate microbicides. Aids Research and Human Retroviruses. 22: 419-24. PMID 16706618 DOI: 10.1089/aid.2006.22.419  0.88
2006 Isaacs CE, Rohan L, Xu W, Jia JH, Mietzner T, Hillier S. Inactivation of herpes simplex virus clinical isolates by using a combination microbicide Antimicrobial Agents and Chemotherapy. 50: 1063-1066. PMID 16495269 DOI: 10.1128/AAC.50.3.1063-1066.2006  0.88
2005 Poloyac SM, Rohan LC, Janjic JM, Gibbs RB, Kroboth PD, Smith RB. Graduate Education and Research at the University of Pittsburgh (GEAR-UP): A program to educate students about pharmaceutical research American Journal of Pharmaceutical Education. 69.  0.88
2004 Lampe MF, Rohan LC, Skinner MC, Stamm WE. Susceptibility of Chlamydia trachomatis to excipients commonly used in topical microbicide formulations Antimicrobial Agents and Chemotherapy. 48: 3200-3202. PMID 15273151 DOI: 10.1128/AAC.48.8.3200-3202.2004  0.88
2004 Sassi AB, McCullough KD, Cost MR, Hillier SL, Rohan LC. Permeability of tritiated water through human cervical and vaginal tissue. Journal of Pharmaceutical Sciences. 93: 2009-16. PMID 15236450 DOI: 10.1002/jps.20107  0.88
2004 Rohan LC, Ratner D, McCullough K, Hiller SL, Gupta P. Measurement of anti-HIV activity of marketed vaginal products and excipients using a PBMC-based in vitro assay. Sexually Transmitted Diseases. 31: 143-8. PMID 15076925 DOI: 10.1097/01.OLQ.0000114655.79109.ED  0.88
2003 Olmsted SS, Meyn LA, Rohan LC, Hillier SL. Glycosidase and proteinase activity of anaerobic gram-negative bacteria isolated from women with bacterial vaginosis. Sexually Transmitted Diseases. 30: 257-61. PMID 12616147 DOI: 10.1097/00007435-200303000-00016  0.88
2000 Black CA, Rohan LC, Cost M, Watkins SC, Draviam R, Alber S, Edwards RP. Vaginal mucosa serves as an inductive site for tolerance Journal of Immunology. 165: 5077-5083. PMID 11046038  0.88
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