Xianjun Fang - Publications

Virginia Commonwealth University, Richmond, VA, United States 
Biochemistry, Molecular Biology

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Liu Z, Liu W, Wang W, Ma Y, Wang Y, Drum DL, Cai J, Blevins H, Lee E, Shah S, Fisher PB, Wang X, Fang X, Guo C, Wang XY. CPT1A-mediated fatty acid oxidation confers cancer cell resistance to immune-mediated cytolytic killing. Proceedings of the National Academy of Sciences of the United States of America. 120: e2302878120. PMID 37722058 DOI: 10.1073/pnas.2302878120  0.312
2022 Liu Y, Fang X, Li Y, Bing L, Li Y, Fang J, Xian X, Zhang W, Li J, Zhao Z, Zhu Y. Berberine suppresses the migration and invasion of colon cancer cells by inhibition of lipogenesis through modulation of promyelocytic leukemia zinc finger-mediated sterol-regulatory element binding proteins cleavage-activating protein ubiquitination. The Journal of Pharmacy and Pharmacology. PMID 35641094 DOI: 10.1093/jpp/rgac026  0.312
2020 Wang W, Wu J, Mukherjee A, He T, Wang XY, Ma Y, Fang X. Lysophosphatidic acid induces tumor necrosis factor-alpha to regulate a pro-inflammatory cytokine network in ovarian cancer. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 32851734 DOI: 10.1096/Fj.202001136R  0.384
2020 Ma Y, Wang W, Devarakonda T, Zhou H, Wang XY, Salloum FN, Spiegel S, Fang X. Functional analysis of molecular and pharmacological modulators of mitochondrial fatty acid oxidation. Scientific Reports. 10: 1450. PMID 31996743 DOI: 10.1038/S41598-020-58334-7  0.397
2019 Guo C, Chen S, Liu W, Ma Y, Li J, Fisher PB, Fang X, Wang XY. Immunometabolism: A new target for improving cancer immunotherapy. Advances in Cancer Research. 143: 195-253. PMID 31202359 DOI: 10.1016/Bs.Acr.2019.03.004  0.342
2018 Ma Y, Wang W, Idowu MO, Oh U, Wang XY, Temkin SM, Fang X. Ovarian Cancer Relies on Glucose Transporter 1 to Fuel Glycolysis and Growth: Anti-Tumor Activity of BAY-876. Cancers. 11. PMID 30602670 DOI: 10.3390/Cancers11010033  0.429
2018 Ma Y, Temkin SM, Hawkridge AM, Guo C, Wang W, Wang XY, Fang X. Fatty Acid Oxidation: An Emerging Facet of Metabolic Transformation in Cancer. Cancer Letters. PMID 30102953 DOI: 10.1016/J.Canlet.2018.08.006  0.389
2017 Ma Y, Min HK, Oh U, Hawkridge AM, Wang W, Mohsin AA, Chen Q, Sanyal A, Lesnefsky EJ, Fang X. The lignan manassantin is a potent and specific inhibitor of mitochondrial complex I and bioenergetic activity in mammals. The Journal of Biological Chemistry. PMID 29046352 DOI: 10.1074/Jbc.M117.812925  0.343
2017 Fang X, Hong Y, Dai L, Qian Y, Zhu C, Wu B, Li S. CRH promotes human colon cancer cell proliferation via IL-6/JAK2/STAT3 signaling pathway and VEGF-induced tumor angiogenesis. Molecular Carcinogenesis. PMID 28618089 DOI: 10.1002/mc.22691  0.377
2016 Li J, Yang Z, Chen Z, Bao Y, Zhang H, Fang X, Yang W. ATF3 suppresses ESCC via downregulation of ID1. Oncology Letters. 12: 1642-1648. PMID 27602100 DOI: 10.3892/ol.2016.4832  0.353
2016 Ma Y, Yu C, Mohamed EM, Shao H, Wang L, Sundaresan G, Zweit J, Idowu M, Fang X. A causal link from ALK to hexokinase II overexpression and hyperactive glycolysis in EML4-ALK-positive lung cancer. Oncogene. PMID 27132509 DOI: 10.1038/Onc.2016.150  0.395
2016 Kyte SL, Toma W, Damaj MI, Fang X, Gewirtz DA. Abstract 3574: Nicotine prevents chemotherapy-induced peripheral neuropathy in vivo, and fails to stimulate the growth of lung cancer cells or interfere with the effectiveness of chemotherapy in vitro Cancer Research. 76: 3574-3574. DOI: 10.1158/1538-7445.Am2016-3574  0.375
2015 Shao H, Mohamed EM, Xu GG, Waters M, Jing K, Ma Y, Zhang Y, Spiegel S, Idowu MO, Fang X. Carnitine palmitoyltransferase 1A functions to repress FoxO transcription factors to allow cell cycle progression in ovarian cancer. Oncotarget. PMID 26716645 DOI: 10.18632/Oncotarget.6757  0.502
2015 Li W, Mukherjee A, Wu J, Zhang L, Teves ME, Li H, Nambiar S, Henderson SC, Horwitz AR, Strauss Iii JF, Fang X, Zhang Z. Sperm Associated Antigen 6 (SPAG6) Regulates Fibroblast Cell Growth, Morphology, Migration and Ciliogenesis. Scientific Reports. 5: 16506. PMID 26585507 DOI: 10.1038/Srep16506  0.324
2015 Mukherjee A, Ma Y, Yuan F, Gong Y, Fang Z, Mohamed EM, Berrios E, Shao H, Fang X. Lysophosphatidic Acid Up-Regulates Hexokinase II and Glycolysis to Promote Proliferation of Ovarian Cancer Cells. Neoplasia (New York, N.Y.). 17: 723-34. PMID 26476080 DOI: 10.1016/J.Neo.2015.09.003  0.506
2015 Nepomuceno AI, Shao H, Jing K, Ma Y, Petitte JN, Idowu MO, Muddiman DC, Fang X, Hawkridge AM. In-depth LC-MS/MS analysis of the chicken ovarian cancer proteome reveals conserved and novel differentially regulated proteins in humans. Analytical and Bioanalytical Chemistry. PMID 26159569 DOI: 10.1007/S00216-015-8862-4  0.381
2014 Jin L, Li C, Li R, Sun Z, Fang X, Li S. Corticotropin-releasing hormone receptors mediate apoptosis via cytosolic calcium-dependent phospholipase A₂ and migration in prostate cancer cell RM-1. Journal of Molecular Endocrinology. 52: 255-67. PMID 24776847 DOI: 10.1530/JME-13-0270  0.359
2013 Shao H, Jing K, Mahmoud E, Huang H, Fang X, Yu C. Apigenin sensitizes colon cancer cells to antitumor activity of ABT-263. Molecular Cancer Therapeutics. 12: 2640-50. PMID 24126433 DOI: 10.1158/1535-7163.Mct-13-0066  0.442
2013 Wu J, Mukherjee A, Lebman DA, Fang X. Gene expression of the lysophosphatidic acid receptor 1 is a target of transforming growth factor beta Oncogene. 32: 3198-3206. PMID 22824789 DOI: 10.1038/Onc.2012.325  0.435
2013 Shao H, Jing K, Mahmoud E, Fang X, Yu C. Abstract 3290: Modulation of AKT, ERK and Mcl-1 by apigenin sensitizes colon cancer cells to anti-tumor activities of ABT263. Cancer Research. 73: 3290-3290. DOI: 10.1158/1538-7445.Am2013-3290  0.446
2012 Zhang Y, Arnatt CK, Zhang F, Wang J, Haney KM, Fang X. The potential role of anibamine, a natural product CCR5 antagonist, and its analogues as leads toward development of anti-ovarian cancer agents. Bioorganic & Medicinal Chemistry Letters. 22: 5093-7. PMID 22770928 DOI: 10.1016/J.Bmcl.2012.05.127  0.413
2012 Mukherjee A, Wu J, Barbour S, Fang X. Lysophosphatidic acid activates lipogenic pathways and de novo lipid synthesis in ovarian cancer cells. The Journal of Biological Chemistry. 287: 24990-5000. PMID 22665482 DOI: 10.1074/Jbc.M112.340083  0.507
2012 Van DN, Roberts CF, Marion JD, Lépine S, Harikumar KB, Schreiter J, Dumur CI, Fang X, Spiegel S, Bell JK. Innate immune agonist, dsRNA, induces apoptosis in ovarian cancer cells and enhances the potency of cytotoxic chemotherapeutics. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 3188-98. PMID 22532440 DOI: 10.1096/Fj.11-202333  0.438
2011 Wu J, Mukherjee A, Lebman DA, Fang X. Lysophosphatidic acid-induced p21Waf1 expression mediates the cytostatic response of breast and ovarian cancer cells to TGFβ. Molecular Cancer Research : McR. 9: 1562-70. PMID 21890597 DOI: 10.1158/1541-7786.Mcr-11-0340  0.47
2010 Li L, Lee PS, Yan C, Zhai T, Fang X, Liao M, Koide Y, Bando Y, Golberg D. Ultrahigh-performance solar-blind photodetectors based on individual single-crystalline Inâ‚‚Geâ‚‚O₇ nanobelts. Advanced Materials (Deerfield Beach, Fla.). 22: 5145-9. PMID 20859947 DOI: 10.1002/Adma.201002608  0.351
2010 Ramachandran S, Shida D, Nagahashi M, Fang X, Milstien S, Takabe K, Spiegel S. Lysophosphatidic acid stimulates gastric cancer cell proliferation via ERK1-dependent upregulation of sphingosine kinase 1 transcription. Febs Letters. 584: 4077-82. PMID 20804754 DOI: 10.1016/J.Febslet.2010.08.035  0.498
2010 Song Y, Dilger E, Bell J, Barton WA, Fang X. Large scale purification and characterization of recombinant human autotaxin/lysophospholipase D from mammalian cells. Bmb Reports. 43: 541-6. PMID 20797316 DOI: 10.5483/Bmbrep.2010.43.8.541  0.32
2010 Oyesanya RA, Greenbaum S, Dang D, Lee Z, Mukherjee A, Wu J, Dent P, Fang X. Differential requirement of the epidermal growth factor receptor for G protein-mediated activation of transcription factors by lysophosphatidic acid. Molecular Cancer. 9: 8. PMID 20074357 DOI: 10.1186/1476-4598-9-8  0.699
2009 Liu S, Umezu-Goto M, Murph M, Lu Y, Liu W, Zhang F, Yu S, Stephens LC, Cui X, Murrow G, Coombes K, Muller W, Hung MC, Perou CM, Lee AV, ... Fang X, et al. Expression of autotaxin and lysophosphatidic acid receptors increases mammary tumorigenesis, invasion, and metastases. Cancer Cell. 15: 539-50. PMID 19477432 DOI: 10.1016/J.Ccr.2009.03.027  0.425
2009 Song Y, Wu J, Oyesanya RA, Lee Z, Mukherjee A, Fang X. Sp-1 and c-Myc mediate lysophosphatidic acid-induced expression of vascular endothelial growth factor in ovarian cancer cells via a hypoxia-inducible factor-1-independent mechanism. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 492-501. PMID 19147754 DOI: 10.1158/1078-0432.Ccr-08-1945  0.703
2009 Pamuklar Z, Federico L, Liu S, Umezu-Goto M, Dong A, Panchatcharam M, Fulkerson Z, Fulerson Z, Berdyshev E, Natarajan V, Fang X, van Meeteren LA, Moolenaar WH, Mills GB, Morris AJ, et al. Autotaxin/lysopholipase D and lysophosphatidic acid regulate murine hemostasis and thrombosis. The Journal of Biological Chemistry. 284: 7385-94. PMID 19139100 DOI: 10.1074/Jbc.M807820200  0.307
2008 Yu S, Murph MM, Lu Y, Liu S, Hall HS, Liu J, Stephens C, Fang X, Mills GB. Lysophosphatidic acid receptors determine tumorigenicity and aggressiveness of ovarian cancer cells. Journal of the National Cancer Institute. 100: 1630-42. PMID 19001604 DOI: 10.1093/Jnci/Djn378  0.51
2008 Lee Z, Cheng CT, Zhang H, Subler MA, Wu J, Mukherjee A, Windle JJ, Chen CK, Fang X. Role of LPA4/p2y9/GPR23 in negative regulation of cell motility. Molecular Biology of the Cell. 19: 5435-45. PMID 18843048 DOI: 10.1091/Mbc.E08-03-0316  0.453
2008 Shida D, Fang X, Kordula T, Takabe K, Lépine S, Alvarez SE, Milstien S, Spiegel S. Cross-talk between LPA1 and epidermal growth factor receptors mediates up-regulation of sphingosine kinase 1 to promote gastric cancer cell motility and invasion. Cancer Research. 68: 6569-77. PMID 18701480 DOI: 10.1158/0008-5472.Can-08-0411  0.51
2008 Ishdorj G, Graham BA, Hu X, Chen J, Johnston JB, Fang X, Gibson SB. Lysophosphatidic acid protects cancer cells from histone deacetylase (HDAC) inhibitor-induced apoptosis through activation of HDAC. The Journal of Biological Chemistry. 283: 16818-29. PMID 18408217 DOI: 10.1074/jbc.M710177200  0.311
2008 Liu S, Fang X, Hall H, Yu S, Smith D, Lu Z, Fang D, Liu J, Stephens LC, Woodgett JR, Mills GB. Homozygous deletion of glycogen synthase kinase 3beta bypasses senescence allowing Ras transformation of primary murine fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 105: 5248-53. PMID 18367674 DOI: 10.1073/Pnas.0704242105  0.301
2008 Oyesanya RA, Lee ZP, Wu J, Chen J, Song Y, Mukherjee A, Dent P, Kordula T, Zhou H, Fang X. Transcriptional and post-transcriptional mechanisms for lysophosphatidic acid-induced cyclooxygenase-2 expression in ovarian cancer cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 2639-51. PMID 18362203 DOI: 10.1096/Fj.07-101428  0.717
2007 Song Y, Wilkins P, Hu W, Murthy KS, Chen J, Lee Z, Oyesanya R, Wu J, Barbour SE, Fang X. Inhibition of calcium-independent phospholipase A2 suppresses proliferation and tumorigenicity of ovarian carcinoma cells. The Biochemical Journal. 406: 427-36. PMID 17555408 DOI: 10.1042/Bj20070631  0.714
2006 Lee Z, Swaby RF, Liang Y, Yu S, Liu S, Lu KH, Bast RC, Mills GB, Fang X. Lysophosphatidic acid is a major regulator of growth-regulated oncogene alpha in ovarian cancer. Cancer Research. 66: 2740-8. PMID 16510595 DOI: 10.1158/0008-5472.Can-05-2947  0.529
2004 Liu S, Yu S, Hasegawa Y, Lapushin R, Xu HJ, Woodgett JR, Mills GB, Fang X. Glycogen synthase kinase 3beta is a negative regulator of growth factor-induced activation of the c-Jun N-terminal kinase. The Journal of Biological Chemistry. 279: 51075-81. PMID 15466414 DOI: 10.1074/Jbc.M408607200  0.375
2004 Takada Y, Fang X, Jamaluddin MS, Boyd DD, Aggarwal BB. Genetic deletion of glycogen synthase kinase-3beta abrogates activation of IkappaBalpha kinase, JNK, Akt, and p44/p42 MAPK but potentiates apoptosis induced by tumor necrosis factor. The Journal of Biological Chemistry. 279: 39541-54. PMID 15252041 DOI: 10.1074/Jbc.M403449200  0.348
2004 Fang X, Yu S, Bast RC, Liu S, Xu HJ, Hu SX, LaPushin R, Claret FX, Aggarwal BB, Lu Y, Mills GB. Mechanisms for lysophosphatidic acid-induced cytokine production in ovarian cancer cells. The Journal of Biological Chemistry. 279: 9653-61. PMID 14670967 DOI: 10.1074/Jbc.M306662200  0.334
2003 Tanyi JL, Morris AJ, Wolf JK, Fang X, Hasegawa Y, Lapushin R, Auersperg N, Sigal YJ, Newman RA, Felix EA, Atkinson EN, Mills GB. The human lipid phosphate phosphatase-3 decreases the growth, survival, and tumorigenesis of ovarian cancer cells: validation of the lysophosphatidic acid signaling cascade as a target for therapy in ovarian cancer. Cancer Research. 63: 1073-82. PMID 12615725  0.391
2003 Hasegawa Y, Erickson JR, Goddard GJ, Yu S, Liu S, Cheng KW, Eder A, Bandoh K, Aoki J, Jarosz R, Schrier AD, Lynch KR, Mills GB, Fang X. Identification of a phosphothionate analogue of lysophosphatidic acid (LPA) as a selective agonist of the LPA3 receptor. The Journal of Biological Chemistry. 278: 11962-9. PMID 12554733 DOI: 10.1074/Jbc.M209168200  0.326
2002 Fang X, Schummer M, Mao M, Yu S, Tabassam FH, Swaby R, Hasegawa Y, Tanyi JL, LaPushin R, Eder A, Jaffe R, Erickson J, Mills GB. Lysophosphatidic acid is a bioactive mediator in ovarian cancer. Biochimica Et Biophysica Acta. 1582: 257-64. PMID 12069836 DOI: 10.1016/S1388-1981(02)00179-8  0.415
2002 Mills GB, Eder A, Fang X, Hasegawa Y, Mao M, Lu Y, Tanyi J, Tabassam FH, Wiener J, Lapushin R, Yu S, Parrott JA, Compton T, Tribley W, Fishman D, et al. Critical role of lysophospholipids in the pathophysiology, diagnosis, and management of ovarian cancer. Cancer Treatment and Research. 107: 259-83. PMID 11775454  0.374
2000 Fang X, Yu S, LaPushin R, Lu Y, Furui T, Penn LZ, Stokoe D, Erickson JR, Bast RC, Mills GB. Lysophosphatidic acid prevents apoptosis in fibroblasts via G(i)-protein-mediated activation of mitogen-activated protein kinase. The Biochemical Journal. 352: 135-43. PMID 11062066 DOI: 10.1042/0264-6021:3520135  0.312
2000 Fang X, Gaudette D, Furui T, Mao M, Estrella V, Eder A, Pustilnik T, Sasagawa T, Lapushin R, Yu S, Jaffe RB, Wiener JR, Erickson JR, Mills GB. Lysophospholipid growth factors in the initiation, progression, metastases, and management of ovarian cancer. Annals of the New York Academy of Sciences. 905: 188-208. PMID 10818454 DOI: 10.1111/j.1749-6632.2000.tb06550.x  0.432
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