Bernd Meibohm - Publications

Affiliations: 
Pharmaceutical Sciences University of Tennessee Health Science Center, Memphis, TN, United States 
Area:
Pharmacology, Pharmaceutical Chemistry

127 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Stewart IE, Lukka PB, Liu J, Meibohm B, Gonzalez-Juarrero M, Braunstein MS, Lee RE, Hickey AJ. Development and Characterization of a Dry Powder Formulation for Anti-Tuberculosis Drug Spectinamide 1599. Pharmaceutical Research. 36: 136. PMID 31321552 DOI: 10.1007/s11095-019-2666-8  0.52
2019 Rathi C, Lukka PB, Wagh S, Lee RE, Lenaerts AJ, Braunstein M, Hickey A, Gonzalez-Juarrero M, Meibohm B. Comparative pharmacokinetics of spectinamide 1599 after subcutaneous and intrapulmonary aerosol administration in mice. Tuberculosis (Edinburgh, Scotland). 114: 119-122. PMID 30711150 DOI: 10.1016/j.tube.2018.12.006  0.52
2018 Vaddady PK, Trivedi A, Rathi C, Madhura DB, Liu J, Lee RE, Meibohm B. Dynamic time-kill curve characterization of spectinamide antibiotics 1445 and 1599 for the treatment of tuberculosis. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. PMID 30419293 DOI: 10.1016/j.ejps.2018.11.006  0.52
2017 He H, Ma D, Crone LB, Butawan M, Meibohm B, Bloomer RJ, Yates CR. Assessment of the Drug-Drug Interaction Potential Between Theacrine and Caffeine in Humans. Journal of Caffeine Research. 7: 95-102. PMID 28875060 DOI: 10.1089/jcr.2017.0006  0.68
2017 Liu J, Bruhn DF, Lee RB, Zheng Z, Janusic T, Scherbakov D, Scherman MS, Boshoff HI, Das S, Rakesh, Waidyarachchi SL, Brewer TA, Gracia B, Yang L, Bollinger J, ... ... Meibohm B, et al. Structure-Activity Relationships of Spectinamide Antituberculosis Agents: A Dissection of Ribosomal Inhibition and Native Efflux Avoidance Contributions. Acs Infectious Diseases. 3: 72-88. PMID 28081607 DOI: 10.1021/acsinfecdis.6b00158  0.52
2016 Rathi C, Lee RE, Meibohm B. Translational PK/PD of anti-infective therapeutics. Drug Discovery Today. Technologies. 21: 41-49. PMID 27978987 DOI: 10.1016/j.ddtec.2016.08.004  0.52
2016 Mould DR, Meibohm B. Drug Development of Therapeutic Monoclonal Antibodies. Biodrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy. PMID 27342605 DOI: 10.1007/s40259-016-0181-6  0.72
2016 Leeder JS, Meibohm B. Challenges and Opportunities for Increasing the Knowledge Base Related to Drug Biotransformation and Pharmacokinetics during Growth and Development. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 44: 916-23. PMID 27302933 DOI: 10.1124/dmd.116.071159  0.72
2016 Thomson MM, Hines RN, Schuetz EG, Meibohm B. Expression Patterns of OATP 1B1 and OATP 1B3 Protein in Human Pediatric Liver. Drug Metabolism and Disposition: the Biological Fate of Chemicals. PMID 27098745 DOI: 10.1124/dmd.115.069252  0.72
2016 Madhura DB, Liu J, Meibohm B, Lee RE. Phase II Metabolic Pathways of Spectinamide Antitubercular Agents: A Comparative Study of the Reactivity of 4-Substituted Pyridines to Glutathione Conjugation. Medchemcomm. 7: 114-117. PMID 27042286 DOI: 10.1039/C5MD00349K  0.52
2016 Madhura DB, Trivedi A, Liu J, Boyd VA, Jeffries C, Loveless V, Lee RE, Meibohm B. Tissue Penetration of a Novel Spectinamide Antibiotic for the Treatment of Tuberculosis. The Aaps Journal. PMID 26984832 DOI: 10.1208/s12248-016-9900-7  0.72
2016 Midde NM, Rahman MA, Rathi C, Li J, Meibohm B, Li W, Kumar S. Effect of Ethanol on the Metabolic Characteristics of HIV-1 Integrase Inhibitor Elvitegravir and Elvitegravir/Cobicistat with CYP3A: An Analysis Using a Newly Developed LC-MS/MS Method. Plos One. 11: e0149225. PMID 26872388 DOI: 10.1371/journal.pone.0149225  0.72
2016 Gabrielsson J, Meibohm B, Weiner D. Pattern Recognition in Pharmacokinetic Data Analysis. The Aaps Journal. 18: 47-63. PMID 26338231 DOI: 10.1208/s12248-015-9817-6  0.72
2016 Madhura DB, Liu J, Meibohm B, Lee RE. Phase II metabolic pathways of spectinamide antitubercular agents: A comparative study of the reactivity of 4-substituted pyridines to glutathione conjugation Medchemcomm. 7: 114-117. DOI: 10.1039/c5md00349k  0.72
2016 Sharma A, Weber B, Wein M, Hallmann C, Meibohm B. Essential criteria for pharmacokinetic studies supporting bioequivalence of inhaled tiotropium bromide products Clinical Pharmacology in Drug Development. 5: 52-56. DOI: 10.1002/cpdd.187  0.72
2015 Barnes RC, Krenek KA, Meibohm B, Mertens-Talcott1 SU, Talcott ST. Urinary Metabolites from Mango (Mangifera indica L. cv. Keitt) Galloyl Derivatives and In Vitro Hydrolysis of Gallotannins in Physiological Conditions. Molecular Nutrition & Food Research. PMID 26640139 DOI: 10.1002/mnfr.201500706  0.72
2015 Gunn GR, Sealey DC, Jamali F, Meibohm B, Ghosh S, Shankar G. From the Bench to Clinical Practice: Understanding the Challenges and Uncertainties in Immunogenicity Testing for Biopharmaceuticals. Clinical and Experimental Immunology. PMID 26597698 DOI: 10.1111/cei.12742  0.72
2015 Bruhn DF, Scherman MS, Liu J, Scherbakov D, Meibohm B, Böttger EC, Lenaerts AJ, Lee RE. In vitro and in vivo Evaluation of Synergism between Anti-Tubercular Spectinamides and Non-Classical Tuberculosis Antibiotics. Scientific Reports. 5: 13985. PMID 26365087 DOI: 10.1038/srep13985  0.72
2015 Brouwer KL, Aleksunes LM, Brandys B, Giacoia GP, Knipp G, Lukacova V, Meibohm B, Nigam SK, Rieder M, de Wildt SN. Human Ontogeny of Drug Transporters: Review and Recommendations of the Pediatric Transporter Working Group. Clinical Pharmacology and Therapeutics. 98: 266-87. PMID 26088472 DOI: 10.1002/cpt.176  0.72
2015 Bruhn DF, Waidyarachchi SL, Madhura DB, Shcherbakov D, Zheng Z, Liu J, Abdelrahman YM, Singh AP, Duscha S, Rathi C, Lee RB, Belland RJ, Meibohm B, Rosch JW, Böttger EC, et al. Aminomethyl spectinomycins as therapeutics for drug-resistant respiratory tract and sexually transmitted bacterial infections. Science Translational Medicine. 7: 288ra75. PMID 25995221 DOI: 10.1126/scitranslmed.3010572  0.72
2015 Diao L, Meibohm B. Tools for predicting the PK/PD of therapeutic proteins. Expert Opinion On Drug Metabolism & Toxicology. 11: 1115-25. PMID 25936400 DOI: 10.1517/17425255.2015.1041917  0.72
2015 Rathi C, Meibohm B. Clinical pharmacology of bispecific antibody constructs. Journal of Clinical Pharmacology. 55: S21-8. PMID 25707960 DOI: 10.1002/jcph.445  0.72
2015 Zhang Y, Wei X, Bajaj G, Barrett JS, Meibohm B, Joshi A, Gupta M. Challenges and considerations for development of therapeutic proteins in pediatric patients. Journal of Clinical Pharmacology. 55: S103-15. PMID 25707958 DOI: 10.1002/jcph.382  0.72
2015 Chhim RF, Crill CM, Collier HK, Arnold SR, Pourcyrous M, Meibohm B, Christensen M. Ethanol lock therapy: a pilot infusion study in infants. The Annals of Pharmacotherapy. 49: 431-6. PMID 25632063 DOI: 10.1177/1060028015569881  0.72
2015 Parker RB, Hu ZY, Meibohm B, Laizure SC. Effects of alcohol on human carboxylesterase drug metabolism. Clinical Pharmacokinetics. 54: 627-38. PMID 25511794 DOI: 10.1007/s40262-014-0226-2  0.72
2014 Meibohm B. Protein engineering for improved pharmacologic characteristics of established monoclonal antibody-based therapeutics. Clinical Pharmacokinetics. 53: 863-4. PMID 25212704 DOI: 10.1007/s40262-014-0186-6  0.72
2014 Tang W, Kowgier M, Loth DW, Soler Artigas M, Joubert BR, Hodge E, Gharib SA, Smith AV, Ruczinski I, Gudnason V, Mathias RA, Harris TB, Hansel NN, Launer LJ, Barnes KC, ... ... Meibohm B, et al. Large-scale genome-wide association studies and meta-analyses of longitudinal change in adult lung function. Plos One. 9: e100776. PMID 24983941 DOI: 10.1371/journal.pone.0100776  0.72
2014 Feagan BG, Choquette D, Ghosh S, Gladman DD, Ho V, Meibohm B, Zou G, Xu Z, Shankar G, Sealey DC, Russell AS. The challenge of indication extrapolation for infliximab biosimilars. Biologicals : Journal of the International Association of Biological Standardization. 42: 177-83. PMID 24962198 DOI: 10.1016/j.biologicals.2014.05.005  0.72
2014 Rakesh, Bruhn DF, Scherman MS, Woolhiser LK, Madhura DB, Maddox MM, Singh AP, Lee RB, Hurdle JG, McNeil MR, Lenaerts AJ, Meibohm B, Lee RE. Pentacyclic nitrofurans with in vivo efficacy and activity against nonreplicating Mycobacterium tuberculosis. Plos One. 9: e87909. PMID 24505329 DOI: 10.1371/journal.pone.0087909  0.72
2014 Swaminathan S, Li H, Palamoor M, de Obarrio WT, Madhura D, Meibohm B, Jablonski MM. Novel endogenous glycan therapy for retinal diseases: safety, in vitro stability, ocular pharmacokinetic modeling, and biodistribution. The Aaps Journal. 16: 311-23. PMID 24470212 DOI: 10.1208/s12248-014-9563-1  0.72
2014 Lee RE, Hurdle JG, Liu J, Bruhn DF, Matt T, Scherman MS, Vaddady PK, Zheng Z, Qi J, Akbergenov R, Das S, Madhura DB, Rathi C, Trivedi A, Villellas C, ... ... Meibohm B, et al. Spectinamides: a new class of semisynthetic antituberculosis agents that overcome native drug efflux. Nature Medicine. 20: 152-8. PMID 24464186 DOI: 10.1038/nm.3458  0.72
2013 Ramusovic S, Läer S, Meibohm B, Lagler FB, Paul T. Pharmacokinetics of intravenous amiodarone in children. Archives of Disease in Childhood. 98: 989-93. PMID 24051016 DOI: 10.1136/archdischild-2013-304483  0.72
2013 Madhura DB, Lee R, Meibohm B. Pharmacokinetic profile of spectinomycin in rats Pharmazie. 68: 675-676. PMID 24020122 DOI: 10.1691/ph.2013.3501  0.72
2013 Diao L, Meibohm B. Pharmacokinetics and pharmacokinetic-pharmacodynamic correlations of therapeutic peptides. Clinical Pharmacokinetics. 52: 855-68. PMID 23719681 DOI: 10.1007/s40262-013-0079-0  0.72
2013 Tang W, Bentley AR, Kritchevsky SB, Harris TB, Newman AB, Bauer DC, Meibohm B, Cassano PA. Genetic variation in antioxidant enzymes, cigarette smoking, and longitudinal change in lung function. Free Radical Biology & Medicine. 63: 304-12. PMID 23688726 DOI: 10.1016/j.freeradbiomed.2013.05.016  0.72
2013 Trivedi A, Lee RE, Meibohm B. Applications of pharmacometrics in the clinical development and pharmacotherapy of anti-infectives. Expert Review of Clinical Pharmacology. 6: 159-70. PMID 23473593 DOI: 10.1586/ecp.13.6  0.72
2013 Bai JP, Barrett JS, Burckart GJ, Meibohm B, Sachs HC, Yao L. Strategic biomarkers for drug development in treating rare diseases and diseases in neonates and infants. The Aaps Journal. 15: 447-54. PMID 23334978 DOI: 10.1208/s12248-013-9452-z  0.72
2013 Thudium K, Bilic S, Leipold D, Mallet W, Kaur S, Meibohm B, Erickson H, Tibbitts J, Zhao H, Gupta M. American Association of Pharmaceutical Scientists National Biotechnology Conference Short Course: Translational Challenges in Developing Antibody-Drug Conjugates: May 24, 2012, San Diego, CA. Mabs. 5: 5-12. PMID 23255090 DOI: 10.4161/mabs.22909  0.72
2013 Della Casa Alberighi O, Barrett JS, Läer S, Meibohm B. Response to "physiologically based pharmacokinetic modeling at the extremes of age", Clinical Pharmacology and Therapeutics. 93: 149. PMID 23187875 DOI: 10.1038/clpt.2012.200  0.72
2013 Hu ZY, Laizure SC, Meibohm B, Herring VL, Parker RB. Simple and sensitive assay for quantification of oseltamivir and its active metabolite oseltamivir carboxylate in human plasma using high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry: improved applicability to pharmacokinetic study. Journal of Pharmaceutical and Biomedical Analysis. 72: 245-50. PMID 23000242 DOI: 10.1016/j.jpba.2012.08.029  0.72
2013 Kelmer G, Bell GC, Martin-Jimenez T, Saxton AM, Catasus C, Elliot SB, Meibohm B. Evaluation of regional limb perfusion with amikacin using the saphenous, cephalic, and palmar digital veins in standing horses. Journal of Veterinary Pharmacology and Therapeutics. 36: 236-40. PMID 22607056 DOI: 10.1111/j.1365-2885.2012.01414.x  0.72
2013 Meibohm B. Pharmacokinetics and pharmacodynamics of peptide and protein therapeutics Pharmaceutical Biotechnology: Fundamentals and Applications, Fourth Edition. 101-132. DOI: 10.1007/978-1-4614-6486-0_5  0.72
2013 Crommelin DJA, Sindelar RD, Meibohm B. Pharmaceutical biotechnology: Fundamentals and applications, Fourth edition Pharmaceutical Biotechnology: Fundamentals and Applications, Fourth Edition. 1-544. DOI: 10.1007/978-1-4614-6486-0  0.72
2012 Hancock DB, Artigas MS, Gharib SA, Henry A, Manichaikul A, Ramasamy A, Loth DW, Imboden M, Koch B, McArdle WL, Smith AV, Smolonska J, Sood A, Tang W, Wilk JB, ... ... Meibohm B, et al. Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function. Plos Genetics. 8: e1003098. PMID 23284291 DOI: 10.1371/journal.pgen.1003098  0.72
2012 Rakesh, Bruhn D, Madhura DB, Maddox M, Lee RB, Trivedi A, Yang L, Scherman MS, Gilliland JC, Gruppo V, McNeil MR, Lenaerts AJ, Meibohm B, Lee RE. Antitubercular nitrofuran isoxazolines with improved pharmacokinetic properties. Bioorganic & Medicinal Chemistry. 20: 6063-72. PMID 22995771 DOI: 10.1016/j.bmc.2012.08.023  0.72
2012 Swanson JM, Wood GC, Xu L, Tang LE, Meibohm B, Homayouni R, Croce MA, Fabian TC. Developing a gene expression model for predicting ventilator-associated pneumonia in trauma patients: a pilot study. Plos One. 7: e42065. PMID 22916119 DOI: 10.1371/journal.pone.0042065  0.72
2012 Allegaert K, van den Anker JN. Creatinine-based vancomycin dosing regimens in neonates: there is more to consider than the variation in drug assay. Pharmacotherapy. 32: e174; discussion e17. PMID 22859254 DOI: 10.1002/j.1875-9114.2012.01180.x  0.72
2012 Wilk JB, Shrine NR, Loehr LR, Zhao JH, Manichaikul A, Lopez LM, Smith AV, Heckbert SR, Smolonska J, Tang W, Loth DW, Curjuric I, Hui J, Cho MH, Latourelle JC, ... ... Meibohm B, et al. Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction. American Journal of Respiratory and Critical Care Medicine. 186: 622-32. PMID 22837378 DOI: 10.1164/rccm.201202-0366OC  0.72
2012 van den Borst B, Gosker HR, Koster A, Yu B, Kritchevsky SB, Liu Y, Meibohm B, Rice TB, Shlipak M, Yende S, Harris TB, Schols AM. The influence of abdominal visceral fat on inflammatory pathways and mortality risk in obstructive lung disease. The American Journal of Clinical Nutrition. 96: 516-26. PMID 22811442 DOI: 10.3945/ajcn.112.040774  0.72
2012 Aldrich MC, Kumar R, Colangelo LA, Williams LK, Sen S, Kritchevsky SB, Meibohm B, Galanter J, Hu D, Gignoux CR, Liu Y, Harris TB, Ziv E, Zmuda J, Garcia M, et al. Genetic ancestry-smoking interactions and lung function in African Americans: a cohort study. Plos One. 7: e39541. PMID 22737244 DOI: 10.1371/journal.pone.0039541  0.72
2012 Barrett JS, Della Casa Alberighi O, Läer S, Meibohm B. Physiologically Based Pharmacokinetic (PBPK) modeling in children Clinical Pharmacology and Therapeutics. 92: 40-49. PMID 22669290 DOI: 10.1038/clpt.2012.64  0.72
2012 Mehrotra N, Tang L, Phelps SJ, Meibohm B. Evaluation of vancomycin dosing regimens in preterm and term neonates using Monte Carlo simulations. Pharmacotherapy. 32: 408-19. PMID 22488303 DOI: 10.1002/j.1875-9114.2012.01029.x  0.72
2012 Chirmule N, Jawa V, Meibohm B. Immunogenicity to therapeutic proteins: impact on PK/PD and efficacy. The Aaps Journal. 14: 296-302. PMID 22407289 DOI: 10.1208/s12248-012-9340-y  0.72
2012 Bentley AR, Kritchevsky SB, Harris TB, Newman AB, Bauer DC, Meibohm B, Clark AG, Cassano PA. Genetic variation in antioxidant enzymes and lung function. Free Radical Biology & Medicine. 52: 1577-83. PMID 22387199 DOI: 10.1016/j.freeradbiomed.2012.02.025  0.72
2012 Meibohm B, Zhou H. Characterizing the impact of renal impairment on the clinical pharmacology of biologics. Journal of Clinical Pharmacology. 52: 54S-62S. PMID 22232754 DOI: 10.1177/0091270011413894  0.72
2012 Meibohm B. Pharmacokinetics and Half-Life of Protein Therapeutics Therapeutic Proteins: Strategies to Modulate Their Plasma Half-Lives. 23-38. DOI: 10.1002/9783527644827.ch2  0.72
2012 Zhang Y, Meibohm B. Pharmacokinetics and Pharmacodynamics of Therapeutic Peptides and Proteins Pharmaceutical Biotechnology: Drug Discovery and Clinical Applications. 337-367. DOI: 10.1002/9783527632909.ch14  0.72
2012 Lee DSH, De Rekeneire N, Hanlon JT, Gill TM, Bauer DC, Meibohm B, Harris TB, Jeffery SM. Cognitive impairment and medication complexity in community-living older adults: The health, aging and body composition study Journal of Pharmacy Technology. 28: 156-162.  0.72
2011 Meibohm B. Population pharmacokinetic/pharmacodynamic analyses as the basis for dosing of therapeutic monoclonal antibodies. Clinical Pharmacokinetics. 50: 823-4. PMID 22087868 DOI: 10.2165/11597950-000000000-00000  0.72
2011 Budha NR, Kovar A, Meibohm B. Comparative performance of cell life span and cell transit models for describing erythropoietic drug effects. The Aaps Journal. 13: 650-61. PMID 22005901 DOI: 10.1208/s12248-011-9302-9  0.72
2011 Prado ME, Ryman JT, Boileau MJ, Martin-Jimenez T, Meibohm B. Pharmacokinetics of ponazuril after oral administration to healthy llamas (Lama glama). American Journal of Veterinary Research. 72: 1386-9. PMID 21962282 DOI: 10.2460/ajvr.72.10.1386  0.72
2011 Läer S, Meibohm B. Study design and simulation approach. Handbook of Experimental Pharmacology. 205: 125-48. PMID 21882109 DOI: 10.1007/978-3-642-20195-0_6  0.72
2011 van den Borst B, Koster A, Yu B, Gosker HR, Meibohm B, Bauer DC, Kritchevsky SB, Liu Y, Newman AB, Harris TB, Schols AM. Is age-related decline in lean mass and physical function accelerated by obstructive lung disease or smoking? Thorax. 66: 961-9. PMID 21724748 DOI: 10.1136/thoraxjnl-2011-200010  0.72
2011 Bai JP, Bell R, Buckman S, Burckart GJ, Eichler HG, Fang KC, Goodsaid FM, Jusko WJ, Lesko LL, Meibohm B, Patterson SD, Puig O, Smerage JB, Snider BJ, Wagner JA, et al. Translational biomarkers: from preclinical to clinical a report of 2009 AAPS/ACCP Biomarker Workshop. The Aaps Journal. 13: 274-83. PMID 21448748 DOI: 10.1208/s12248-011-9265-x  0.72
2011 Vaddady PK, Mehrotra N, Zhang X, Yates CR, Moore BM, Meibohm B. Pharmacokinetics of a combination of Δ9-tetrahydro-cannabinol and celecoxib in a porcine model of hemorrhagic shock. Biopharmaceutics & Drug Disposition. 32: 89-98. PMID 21341278 DOI: 10.1002/bdd.740  0.72
2010 Suryawanshi S, Zhang L, Pfister M, Meibohm B. The current role of model-based drug development. Expert Opinion On Drug Discovery. 5: 311-21. PMID 22823084 DOI: 10.1517/17460441003713470  0.72
2010 Vaddady PK, Lee RE, Meibohm B. In vitro pharmacokinetic/pharmacodynamic models in anti-infective drug development: focus on TB. Future Medicinal Chemistry. 2: 1355-69. PMID 21359155 DOI: 10.4155/fmc.10.224  0.72
2010 Chen J, Wang Z, Li CM, Lu Y, Vaddady PK, Meibohm B, Dalton JT, Miller DD, Li W. Discovery of novel 2-aryl-4-benzoyl-imidazoles targeting the colchicines binding site in tubulin as potential anticancer agents. Journal of Medicinal Chemistry. 53: 7414-27. PMID 20919720 DOI: 10.1021/jm100884b  0.72
2010 Romero K, Corrigan B, Tornoe CW, Gobburu JV, Danhof M, Gillespie WR, Gastonguay MR, Meibohm B, Derendorf H. Pharmacometrics as a discipline is entering the "industrialization" phase: standards, automation, knowledge sharing, and training are critical for future success. Journal of Clinical Pharmacology. 50: 9S-19S. PMID 20881213 DOI: 10.1177/0091270010377788  0.72
2010 Dirks NL, Meibohm B. Population pharmacokinetics of therapeutic monoclonal antibodies. Clinical Pharmacokinetics. 49: 633-59. PMID 20818831 DOI: 10.2165/11535960-000000000-00000  0.72
2010 Kumar R, Seibold MA, Aldrich MC, Williams LK, Reiner AP, Colangelo L, Galanter J, Gignoux C, Hu D, Sen S, Choudhry S, Peterson EL, Rodriguez-Santana J, Rodriguez-Cintron W, Nalls MA, ... ... Meibohm B, et al. Genetic ancestry in lung-function predictions. The New England Journal of Medicine. 363: 321-30. PMID 20647190 DOI: 10.1056/NEJMoa0907897  0.72
2010 Mehrotra N, Freire AX, Bauer DC, Harris TB, Newman AB, Kritchevsky SB, Meibohm B. Predictors of mortality in elderly subjects with obstructive airway disease: the PILE score. Annals of Epidemiology. 20: 223-32. PMID 20159492 DOI: 10.1016/j.annepidem.2009.11.005  0.72
2010 Sharma A, Pibarot P, Pilote S, Dumesnil JG, Arsenault M, Bélanger PM, Meibohm B, Hamelin BA. Toward optimal treatment in women: the effect of sex on metoprolol-diphenhydramine interaction. Journal of Clinical Pharmacology. 50: 214-25. PMID 19948945 DOI: 10.1177/0091270009340417  0.72
2009 Budha NR, Lee RB, Hurdle JG, Lee RE, Meibohm B. A simple in vitro PK/PD model system to determine time-kill curves of drugs against Mycobacteria. Tuberculosis (Edinburgh, Scotland). 89: 378-85. PMID 19748318 DOI: 10.1016/j.tube.2009.08.002  0.72
2009 Läer S, Barrett JS, Meibohm B. The in silico child: using simulation to guide pediatric drug development and manage pediatric pharmacotherapy. Journal of Clinical Pharmacology. 49: 889-904. PMID 19531673 DOI: 10.1177/0091270009337513  0.72
2008 Dirks NL, Li S, Huth B, Hochhaus G, Yates CR, Meibohm B. Transrepression and transactivation potencies of inhaled glucocorticoids. Die Pharmazie. 63: 893-8. PMID 19177906 DOI: 10.1691/ph.2008.8638  0.72
2008 Zhang L, Pfister M, Meibohm B. Concepts and challenges in quantitative pharmacology and model-based drug development. The Aaps Journal. 10: 552-9. PMID 19003542 DOI: 10.1208/s12248-008-9062-3  0.72
2008 Zhang Y, Mehrotra N, Budha NR, Christensen ML, Meibohm B. A tandem mass spectrometry assay for the simultaneous determination of acetaminophen, caffeine, phenytoin, ranitidine, and theophylline in small volume pediatric plasma specimens. Clinica Chimica Acta; International Journal of Clinical Chemistry. 398: 105-12. PMID 18796299 DOI: 10.1016/j.cca.2008.08.023  0.72
2008 Mertens-Talcott SU, Rios J, Jilma-Stohlawetz P, Pacheco-Palencia LA, Meibohm B, Talcott ST, Derendorf H. Pharmacokinetics of anthocyanins and antioxidant effects after the consumption of anthocyanin-rich acai juice and pulp (Euterpe oleracea Mart.) in human healthy volunteers. Journal of Agricultural and Food Chemistry. 56: 7796-802. PMID 18693743 DOI: 10.1021/jf8007037  0.72
2008 Hurdle JG, Lee RB, Budha NR, Carson EI, Qi J, Scherman MS, Cho SH, McNeil MR, Lenaerts AJ, Franzblau SG, Meibohm B, Lee RE. A microbiological assessment of novel nitrofuranylamides as anti-tuberculosis agents. The Journal of Antimicrobial Chemotherapy. 62: 1037-45. PMID 18693235 DOI: 10.1093/jac/dkn307  0.72
2008 Budha NR, Mehrotra N, Tangallapally R, Rakesh, Qi J, Daniels AJ, Lee RE, Meibohm B. Pharmacokinetically-guided lead optimization of nitrofuranylamide anti-tuberculosis agents. The Aaps Journal. 10: 157-65. PMID 18446516 DOI: 10.1208/s12248-008-9017-8  0.72
2008 Budha NR, Lee RE, Meibohm B. Biopharmaceutics, pharmacokinetics and pharmacodynamics of antituberculosis drugs. Current Medicinal Chemistry. 15: 809-25. PMID 18393850 DOI: 10.2174/092986708783955509  0.72
2008 Dirks NL, Nolting A, Kovar A, Meibohm B. Population pharmacokinetics of cetuximab in patients with squamous cell carcinoma of the head and neck. Journal of Clinical Pharmacology. 48: 267-78. PMID 18218786 DOI: 10.1177/0091270007313393  0.72
2008 Albers S, Meibohm B, Mir TS, Läer S. Population pharmacokinetics and dose simulation of carvedilol in paediatric patients with congestive heart failure. British Journal of Clinical Pharmacology. 65: 511-22. PMID 17995971 DOI: 10.1111/j.1365-2125.2007.03046.x  0.72
2007 Tangallapally RP, Sun D, Rakesh, Budha N, Lee RE, Lenaerts AJ, Meibohm B, Lee RE. Discovery of novel isoxazolines as anti-tuberculosis agents. Bioorganic & Medicinal Chemistry Letters. 17: 6638-42. PMID 17937983 DOI: 10.1016/j.bmcl.2007.09.048  0.72
2007 Chen ML, Straughn AB, Sadrieh N, Meyer M, Faustino PJ, Ciavarella AB, Meibohm B, Yates CR, Hussain AS. A modern view of excipient effects on bioequivalence: case study of sorbitol. Pharmaceutical Research. 24: 73-80. PMID 17048115 DOI: 10.1007/s11095-006-9120-4  0.72
2007 Mehrotra N, Gupta M, Kovar A, Meibohm B. The role of pharmacokinetics and pharmacodynamics in phosphodiesterase-5 inhibitor therapy. International Journal of Impotence Research. 19: 253-64. PMID 16988721 DOI: 10.1038/sj.ijir.3901522  0.72
2006 Song P, Lamba JK, Zhang L, Schuetz E, Shukla N, Meibohm B, Yates CR. G2677T and C3435T genotype and haplotype are associated with hepatic ABCB1 (MDR1) expression. Journal of Clinical Pharmacology. 46: 373-9. PMID 16490813 DOI: 10.1177/0091270005284387  0.72
2006 Tang L, Meibohm B. Pharmacokinetics of Peptides and Proteins Pharmacokinetics and Pharmacodynamics of Biotech Drugs: Principles and Case Studies in Drug Development. 15-43. DOI: 10.1002/9783527609628.ch2  0.72
2006 Meibohm B. The Role of Pharmacokinetics and Pharmacodynamics in the Development of Biotech Drugs Pharmacokinetics and Pharmacodynamics of Biotech Drugs: Principles and Case Studies in Drug Development. 1-13. DOI: 10.1002/9783527609628.ch1  0.72
2006 Meibohm B. Preface Pharmacokinetics and Pharmacodynamics of Biotech Drugs: Principles and Case Studies in Drug Development. DOI: 10.1002/9783527609628  0.72
2005 Song P, Meibohm B, Yates CR. LC/MS/MS in drug development: targeting the brain. Biotechniques. 19-23. PMID 16528912  0.72
2005 Meibohm B, Läer S, Panetta JC, Barrett JS. Population pharmacokinetic studies in pediatrics: issues in design and analysis. The Aaps Journal. 7: E475-87. PMID 16353925 DOI: 10.1208/aapsj070248  0.72
2005 Läer S, Elshoff JP, Meibohm B, Weil J, Mir TS, Zhang W, Hulpke-Wette M. Development of a safe and effective pediatric dosing regimen for sotalol based on population pharmacokinetics and pharmacodynamics in children with supraventricular tachycardia. Journal of the American College of Cardiology. 46: 1322-30. PMID 16198851 DOI: 10.1016/j.jacc.2005.06.061  0.72
2005 Christensen ML, Meibohm B, Capparelli EV, Velasquez-Mieyer P, Burghen GA, Tamborlane WV. Single- and multiple-dose pharmacokinetics of pioglitazone in adolescents with type 2 diabetes. Journal of Clinical Pharmacology. 45: 1137-44. PMID 16172178 DOI: 10.1177/0091270005279578  0.72
2005 Gupta M, Kovar A, Meibohm B. The clinical pharmacokinetics of phosphodiesterase-5 inhibitors for erectile dysfunction. Journal of Clinical Pharmacology. 45: 987-1003. PMID 16100293 DOI: 10.1177/0091270005276847  0.72
2005 Gupta M, Yates CR, Meibohm B. SYBR Green-based real-time PCR allelic discrimination assay for beta2-adrenergic receptor polymorphisms. Analytical Biochemistry. 344: 292-4. PMID 16026755 DOI: 10.1016/j.ab.2005.05.018  0.72
2005 Sharma A, Pibarot P, Pilote S, Dumesnil JG, Arsenault M, Bélanger PM, Meibohm B, Hamelin BA. Modulation of metoprolol pharmacokinetics and hemodynamics by diphenhydramine coadministration during exercise testing in healthy premenopausal women. The Journal of Pharmacology and Experimental Therapeutics. 313: 1172-81. PMID 15718288 DOI: 10.1124/jpet.104.081109  0.72
2004 Dirks NL, Huth B, Yates CR, Meibohm B. Pharmacokinetics of immunosuppressants: a perspective on ethnic differences. International Journal of Clinical Pharmacology and Therapeutics. 42: 701-18. PMID 15624287  0.72
2004 Tang L, Persky AM, Hochhaus G, Meibohm B. Pharmacokinetic aspects of biotechnology products. Journal of Pharmaceutical Sciences. 93: 2184-204. PMID 15295780 DOI: 10.1002/jps.20125  0.72
2004 Gupta M, Song P, Yates CR, Meibohm B. Real-time PCR-based genotyping assay for CXCR2 polymorphisms. Clinica Chimica Acta; International Journal of Clinical Chemistry. 341: 93-100. PMID 14967163 DOI: 10.1016/j.cccn.2003.11.017  0.72
2003 Yates CR, Zhang W, Song P, Li S, Gaber AO, Kotb M, Honaker MR, Alloway RR, Meibohm B. The effect of CYP3A5 and MDR1 polymorphic expression on cyclosporine oral disposition in renal transplant patients. Journal of Clinical Pharmacology. 43: 555-64. PMID 12817518  0.72
2002 Song P, Li S, Meibohm B, Gaber AO, Honaker MR, Kotb M, Yates CR. Detection of MDR1 single nucleotide polymorphisms C3435T and G2677T using real-time polymerase chain reaction: MDR1 single nucleotide polymorphism genotyping assay. Aaps Pharmsci. 4: E29. PMID 12646001 DOI: 10.1208/ps040429  0.72
2002 Läer S, Mir TS, Behn F, Eiselt M, Scholz H, Venzke A, Meibohm B, Weil J. Carvedilol therapy in pediatric patients with congestive heart failure: a study investigating clinical and pharmacokinetic parameters. American Heart Journal. 143: 916-22. PMID 12040358 DOI: 10.1067/mhj.2002.121265  0.72
2002 Meibohm B, Beierle I, Derendorf H. How important are gender differences in pharmacokinetics? Clinical Pharmacokinetics. 41: 329-42. PMID 12036391 DOI: 10.2165/00003088-200241050-00002  0.72
2002 Meibohm B, Derendorf H. Pharmacokinetic/pharmacodynamic studies in drug product development. Journal of Pharmaceutical Sciences. 91: 18-31. PMID 11782894 DOI: 10.1002/jps.1167  0.72
2001 Läer S, Meibohm B, Mir TS, Hulpke-Wette M. Termination of automatic atrial tachycardia in an infant by adequate sotalol dosing: Indication of clinically relevant age-dependent pharmacokinetics of sotalol European Journal of Clinical Pharmacology. 57: 181-182. PMID 11417452 DOI: 10.1007/s002280100294  0.72
2001 Läer S, Behn F, Scholz H, Mir TS, Weil J, Meibohm B. Carvedilol for pediatric congestive heart failure: Do young children behave like little adults? Clinical Pharmacology and Therapeutics. 69.  0.72
2001 Jungmayr P, Müller-Bohn T, Meier K, Hanpft R, Goldmann-Posch U, Krekel H, Barth J, Eckert-Lill C, Dranitsakis G, Meibohm B, Fischer FJ. Oncological pharmacy: Report on the 9th North German Cytostatics Workshop Deutsche Apotheker Zeitung. 141: 65-79.  0.72
2000 Meibohm B, Zhang W, Beierle I, Meyer MC. Epistaxis associated with elevation of INR in a patient switched to generic warfarin - Another view Pharmacotherapy. 20: 866-871. PMID 10907982  0.72
2000 Derendorf H, Hochhaus G, Krishnaswami S, Meibohm B, Möllmann H. Optimized therapeutic ratio of inhaled corticosteroids using retrometabolism. Die Pharmazie. 55: 223-7. PMID 10756545  0.72
1999 Beierle I, Meibohm B, Derendorf H. Gender differences in pharmacokinetics and pharmacodynamics International Journal of Clinical Pharmacology and Therapeutics. 37: 529-547. PMID 10584975  0.72
1999 Meibohm B, Hochhaus G, Möllmann H, Barth J, Wagner M, Krieg M, Stöckmann R, Derendorf H. A pharmacokinetic/pharmacodynamic approach to predict the cumulative cortisol suppression of inhaled corticosteroids Journal of Pharmacokinetics and Biopharmaceutics. 27: 127-147. PMID 10567952 DOI: 10.1023/A:1020670421957  0.72
1999 Meibohm B, Derendorf H, Möllmann H, Fröhlich P, Tromm A, Wagner M, Homrighausen S, Krieg M, Hochhaus G. Mechanism-based PK/PD model for the lymphocytopenia induced by endogenous and exogenous corticosteroids International Journal of Clinical Pharmacology and Therapeutics. 37: 367-376. PMID 10475139  0.72
1999 Derendorf H, Meibohm B. Modeling of pharmacokinetic/pharmacodynamic (PK/PD) relationships: Concepts and perspectives Pharmaceutical Research. 16: 176-185. PMID 10100300 DOI: 10.1023/A:1011907920641  0.72
1998 Derendorf H, Hochhaus G, Meibohm B, Mollmann H, Barth J. Pharmacokinetics and pharmacodynamics of inhaled corticosteroids Journal of Allergy and Clinical Immunology. 101. PMID 9563369  0.72
1998 Möllmann H, Wagner M, Meibohm B, Hochhaus G, Barth J, Stöckmann R, Krieg M, Weisser H, Falcoz C, Derendorf H. Pharmacokinetic and pharmacodynamic evaluation of fluticasone propionate after inhaled administration European Journal of Clinical Pharmacology. 53: 459-467. PMID 9551705 DOI: 10.1007/s002280050407  0.72
1998 Meibohm B, Möllmann H, Wagner M, Hochhaus G, Möllmann A, Derendorf H. The clinical pharmacology of fluticasone propionate Reviews in Contemporary Pharmacotherapy. 9: 535-549.  0.72
1997 Möllmann H, Derendorf H, Barth J, Meibohm B, Wagner M, Krieg M, Weisser H, Knöller J, Möllmann A, Hochhaus G. Pharmacokinetic/pharmacodynamic evaluation of systemic effects of flunisolide after inhalation Journal of Clinical Pharmacology. 37: 893-903. PMID 9505980  0.72
1997 Meibohm B, Hochhaus G, Rohatagi S, Möllmann H, Barth J, Wagner M, Krieg M, Stöckmann R, Derendorf H. Dependency of cortisol suppression on administration time of inhaled corticosteroids Journal of Clinical Pharmacology. 37: 704-710. PMID 9378842  0.72
1997 Derendorf H, Möllmann H, Hochhaus G, Meibohm B, Barth J. Clinical PK/PD modelling as a tool in drug development of corticosteroids International Journal of Clinical Pharmacology and Therapeutics. 35: 481-488. PMID 9352400  0.72
1997 Meibohm B, Dorendorf H. Basic concepts of pharmacokinetic/pharmacodynamic (PK/PD) modelling International Journal of Clinical Pharmacology and Therapeutics. 35: 401-413. PMID 9352388  0.72
1997 Meibohm B, Hochhaus G, Derendorf H. Time dependency of the pharmacologic response to glucocorticoids Clinical Pharmacology and Therapeutics. 61: 155.  0.72
1997 Meibohm B, Garms T, Meier K, Melzer S, Schwarz S. Pharmacoeconomic benefit of a patient-oriented automated drug distribution system combined with intensive advisory services Journal of Applied Therapeutics. 1: 343-349.  0.72
1996 Rohatagi S, Bye A, Falcoz C, Mackie AE, Meibohm B, Möllmann H, Derendorf H. Dynamic modeling of cortisol reduction after inhaled administration of fluticasone propionate Journal of Clinical Pharmacology. 36: 938-941. PMID 8930781  0.72
1994 Meibohm BW, Führer C, Kleine P. FC54 investigations on the stereoselective pharmacokinetics of mexiletine during chronic oral therapy European Journal of Pharmaceutical Sciences. 2: 114.  0.72
1992 Meibohm B, Wegener S. Mexiletine-theophylline interaction. Pharmacokinetic effects and clinical relevance Krankenhauspharmazie. 13: 331-333.  0.72
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