Bik-Kwoon Tye - Publications

Cornell University, Ithaca, NY, United States 
Biochemistry, Molecular Biology

87 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Li N, Lam WH, Zhai Y, Cheng J, Cheng E, Zhao Y, Gao N, Tye BK. Structure of the origin recognition complex bound to DNA replication origin. Nature. PMID 29973722 DOI: 10.1038/s41586-018-0293-x  0.44
2017 Zhai Y, Tye BK. Structure of the MCM2-7 Double Hexamer and Its Implications for the Mechanistic Functions of the Mcm2-7 Complex. Advances in Experimental Medicine and Biology. 1042: 189-205. PMID 29357059 DOI: 10.1007/978-981-10-6955-0_9  0.44
2017 Zhai Y, Li N, Jiang H, Huang X, Gao N, Tye BK. Unique Roles of the Non-identical MCM Subunits in DNA Replication Licensing. Molecular Cell. 67: 168-179. PMID 28732205 DOI: 10.1016/j.molcel.2017.06.016  0.44
2017 Zhai Y, Cheng E, Wu H, Li N, Yung PY, Gao N, Tye BK. Open-ringed structure of the Cdt1-Mcm2-7 complex as a precursor of the MCM double hexamer. Nature Structural & Molecular Biology. PMID 28191894 DOI: 10.1038/nsmb.3374  0.44
2015 Li N, Zhai Y, Zhang Y, Li W, Yang M, Lei J, Tye BK, Gao N. Structure of the eukaryotic MCM complex at 3.8 Å. Nature. 524: 186-91. PMID 26222030 DOI: 10.1038/nature14685  0.44
2015 Li N, Zhai Y, Zhang Y, Li W, Yang M, Lei J, Tye BK, Gao N. Structure of the eukaryotic MCM complex at 3.8 Å Nature. 524: 186-191. DOI: 10.1038/nature14685  1
2012 Liu C, Wu R, Zhou B, Wang J, Wei Z, Tye BK, Liang C, Zhu G. Structural insights into the Cdt1-mediated MCM2-7 chromatin loading. Nucleic Acids Research. 40: 3208-17. PMID 22140117 DOI: 10.1093/nar/gkr1118  1
2011 Liachko I, Tanaka E, Cox K, Chung SC, Yang L, Seher A, Hallas L, Cha E, Kang G, Pace H, Barrow J, Inada M, Tye BK, Keich U. Novel features of ARS selection in budding yeast Lachancea kluyveri. Bmc Genomics. 12: 633. PMID 22204614 DOI: 10.1186/1471-2164-12-633  1
2011 Li XC, Tye BK. Ploidy dictates repair pathway choice under DNA replication stress Genetics. 187: 1031-1040. PMID 21242538 DOI: 10.1534/genetics.110.125450  1
2010 Tye BK. Old-fashioned genetic screens give new insights to DNA replication. Cell Cycle (Georgetown, Tex.). 9: 4610-1. PMID 21260947 DOI: 10.4161/cc.9.23.13930  1
2010 Liachko I, Bhaskar A, Lee C, Chung SC, Tye BK, Keich U. A comprehensive genome-wide map of autonomously replicating sequences in a naive genome. Plos Genetics. 6: e1000946. PMID 20485513 DOI: 10.1371/journal.pgen.1000946  1
2010 Lee C, Liachko I, Bouten R, Kelman Z, Tye BK. Alternative mechanisms for coordinating polymerase alpha and MCM helicase. Molecular and Cellular Biology. 30: 423-35. PMID 19917723 DOI: 10.1128/MCB.01240-09  1
2009 Li XC, Schimenti JC, Tye BK. Aneuploidy and improved growth are coincident but not causal in a yeast cancer model. Plos Biology. 7: e1000161. PMID 19636358 DOI: 10.1371/journal.pbio.1000161  1
2009 Eisenberg S, Korza G, Carson J, Liachko I, Tye BK. Novel DNA binding properties of the Mcm10 protein from Saccharomyces cerevisiae. The Journal of Biological Chemistry. 284: 25412-20. PMID 19605346 DOI: 10.1074/jbc.M109.033175  1
2009 Tye BK. Memories of Ray Wu by a colleague. Science in China. Series C, Life Sciences / Chinese Academy of Sciences. 52: 133-4. PMID 19277524 DOI: 10.1007/s11427-009-0027-2  1
2009 Liachko I, Tye BK. Mcm10 mediates the interaction between DNA replication and silencing machineries Genetics. 181: 379-391. PMID 19064704 DOI: 10.1534/genetics.108.099101  1
2008 Keich U, Gao H, Garretson JS, Bhaskar A, Liachko I, Donato J, Tye BK. Computational detection of significant variation in binding affinity across two sets of sequences with application to the analysis of replication origins in yeast. Bmc Bioinformatics. 9: 372. PMID 18786274 DOI: 10.1186/1471-2105-9-372  1
2007 Shima N, Alcaraz A, Liachko I, Buske TR, Andrews CA, Munroe RJ, Hartford SA, Tye BK, Schimenti JC. A viable allele of Mcm4 causes chromosome instability and mammary adenocarcinomas in mice. Nature Genetics. 39: 93-8. PMID 17143284 DOI: 10.1038/ng1936  1
2006 Donato JJ, Chung SC, Tye BK. Genome-wide hierarchy of replication origin usage in Saccharomyces cerevisiae. Plos Genetics. 2: e141. PMID 16965179 DOI: 10.1371/journal.pgen.0020141  1
2006 Ong EP, Lin W, Tye BJ, Etoh M. Fast automatic video object segmentation for content-based applications Advances in Image and Video Segmentation. 140-160. DOI: 10.4018/978-1-59140-753-9.ch007  0.32
2006 Donato JJ, Chung SCC, Tye BK. Genome-wide hierarchy of replication origin usage in Saccharomyces cerevisiae Plos Genetics. 2: 1328-1338. DOI: 10.137/journal.pgen.0020141  1
2005 Liachko I, Tye BK. Mcm10 is required for the maintenance of transcriptional silencing in Saccharomyces cerevisiae Genetics. 171: 503-515. PMID 16085704 DOI: 10.1534/genetics.105.042333  1
2004 Tye BK, Chang VK. Dual functional regulators coordinate DNA replication and gene expression in proliferating cells Frontiers in Bioscience : a Journal and Virtual Library. 9: 2548-2555. PMID 15358580  1
2004 Chang VK, Donato JJ, Chan CS, Tye BK. Mcm1 promotes replication initiation by binding specific elements at replication origins. Molecular and Cellular Biology. 24: 6514-24. PMID 15226450 DOI: 10.1128/MCB.24.14.6514-6524.2004  1
2004 Sawyer SL, Cheng IH, Chai W, Tye BK. Mcm10 and Cdc45 cooperate in origin activation in Saccharomyces cerevisiae. Journal of Molecular Biology. 340: 195-202. PMID 15201046 DOI: 10.1016/j.jmb.2004.04.066  1
2003 Christensen TW, Tye BK. Drosophila MCM10 interacts with members of the prereplication complex and is required for proper chromosome condensation. Molecular Biology of the Cell. 14: 2206-15. PMID 12808023 DOI: 10.1091/mbc.E02-11-0706  1
2003 Dziak R, Leishman D, Radovic M, Tye BK, Yankulov K. Evidence for a role of MCM (mini-chromosome maintenance)5 in transcriptional repression of sub-telomeric and Ty-proximal genes in Saccharomyces cerevisiae. The Journal of Biological Chemistry. 278: 27372-81. PMID 12750362 DOI: 10.1074/jbc.M301110200  1
2003 Fitch MJ, Donato JJ, Tye BK. Mcm7, a subunit of the presumptive MCM helicase, modulates its own expression in conjunction with Mcm1. The Journal of Biological Chemistry. 278: 25408-16. PMID 12738768 DOI: 10.1074/jbc.M300699200  1
2003 Araki Y, Kawasaki Y, Sasanuma H, Tye BK, Sugino A. Budding yeast mcm10/dna43 mutant requires a novel repair pathway for viability Genes to Cells. 8: 465-480. PMID 12694535 DOI: 10.1046/j.1365-2443.2003.00648.x  1
2003 Chang VK, Fitch MJ, Donato JJ, Christensen TW, Merchant AM, Tye BK. Mcm1 binds replication origins. The Journal of Biological Chemistry. 278: 6093-100. PMID 12473677 DOI: 10.1074/jbc.M209827200  1
2002 Cheng IH, Roberts LA, Tye BK. Mcm3 is polyubiquitinated during mitosis before establishment of the pre-replication complex. The Journal of Biological Chemistry. 277: 41706-14. PMID 12200430 DOI: 10.1074/jbc.M205793200  1
2002 Yu X, VanLoock MS, Poplawski A, Kelman Z, Xiang T, Tye BK, Egelman EH. The Methanobacterium thermoautotrophicum MCM protein can form heptameric rings. Embo Reports. 3: 792-7. PMID 12151340 DOI: 10.1093/embo-reports/kvf160  1
2002 Lei M, Cheng IH, Roberts LA, McAlear MA, Tye BK. Two mcm3 mutations affect different steps in the initiation of DNA replication. The Journal of Biological Chemistry. 277: 30824-31. PMID 12060653 DOI: 10.1074/jbc.M201816200  1
2002 Ong EP, Tye BJ, Lin WS, Etoh M. An efficient video object segmentation scheme Icassp, Ieee International Conference On Acoustics, Speech and Signal Processing - Proceedings. 4.  0.32
2001 Lei M, Tye BK. Initiating DNA synthesis: From recruiting to activating the MCM complex Journal of Cell Science. 114: 1447-1454. PMID 11282021  1
2001 Li H, Tye BJ, Ong EP, Lin WS, Ko CC. Multiple motion object segmentation based on homogenous region merging Iscas 2001 - 2001 Ieee International Symposium On Circuits and Systems, Conference Proceedings. 5: 175-178. DOI: 10.1109ISCAS.2001.922013  0.32
2001 Li H, Lin WS, Tye BJ, Ong EP, Ko CC. Object segmentation with affine motion similarity measure Proceedings - Ieee International Conference On Multimedia and Expo. 841-844. DOI: 10.1109/ICME.2001.1237853  0.32
2000 Tye BK, Sawyer S. The hexameric eukaryotic MCM helicase: Building symmetry from nonidentical parts Journal of Biological Chemistry. 275: 34833-34836. PMID 10980206 DOI: 10.1074/jbc.R000018200  1
2000 Homesley L, Lei M, Kawasaki Y, Sawyer S, Christensen T, Tye BK. Mcm10 and the MCM2-7 complex interact to initiate DNA synthesis and to release replication factors from origins Genes and Development. 14: 913-926. PMID 10783164  1
2000 Tye BK. Insights into DNA replication from the third domain of life Proceedings of the National Academy of Sciences of the United States of America. 97: 2399-2401. PMID 10716976 DOI: 10.1073/pnas.97.6.2399  1
1999 Tye BK. MCM proteins in DNA replication Annual Review of Biochemistry. 68: 649-686. PMID 10872463 DOI: 10.1146/annurev.biochem.68.1.649  1
1999 Tye BK. Minichromosome maintenance as a genetic assay for defects in DNA replication Methods: a Companion to Methods in Enzymology. 18: 329-334. PMID 10454994 DOI: 10.1006/meth.1999.0793  1
1999 Lin W, Tye B, Ong E, Xiong C, Miki T, Hotani S. Systematic analysis and methodology of real-time DSP implementation for hybrid video coding Ieee International Conference On Image Processing. 3: 847-851.  0.32
1998 Wu C, Weiss K, Yang C, Harris MA, Tye BK, Newlon CS, Simpson RT, Haber JE. Mcm1 regulates donor preference controlled by the recombination enhancer in Saccharomyces mating-type switching. Genes & Development. 12: 1726-37. PMID 9620858  1
1997 Young MR, Suzuki K, Yan H, Gibson S, Tye BK. Nuclear accumulation of Saccharomyces cerevisiae Mcm3 is dependent on its nuclear localization sequence Genes to Cells. 2: 631-643. PMID 9427284  1
1997 Lei M, Kawasaki Y, Young MR, Kihara M, Sugino A, Tye BK. Mcm2 is a target of regulation by Cdc7-Dbf4 during the initiation of DNA synthesis Genes and Development. 11: 3365-3374. PMID 9407029  1
1997 Young MR, Tye BK. Mcm2 and Mcm3 are constitutive nuclear proteins that exhibit distinct isoforms and bind chromatin during specific cell cycle stages of Saccharomyces cerevisiae Molecular Biology of the Cell. 8: 1587-1601. PMID 9285827  1
1997 Merchant AM, Kawasaki Y, Chen Y, Lei M, Tye BK. A lesion in the DNA replication initiation factor Mcm10 induces pausing of elongation forks through chromosomal replication origins in Saccharomyces cerevisiae Molecular and Cellular Biology. 17: 3261-3271. PMID 9154825  1
1997 Tye B, Goh K, Lin W, Powell G, Ohya T, Adachi S. DSP implementation of very low bit rate videoconferencing system Proceedings of the International Conference On Information, Communications and Signal Processing, Icics. 3: 1275-1278.  0.32
1997 Lin W, Goh KH, Tye BJ, Powell GA, Ohya T, Adachi S. Real time H.263 video codec using parallel DSP Ieee International Conference On Image Processing. 2: 586-589.  0.32
1996 Lei M, Kawasaki Y, Tye BK. Physical interactions among Mcm proteins and effects of Mcm dosage on DNA replication in Saccharomyces cerevisiae Molecular and Cellular Biology. 16: 5081-5090. PMID 8756666  1
1995 Chen Y, Tye BK. The yeast Mcm1 protein is regulated posttranscriptionally by the flux of glycolysis Molecular and Cellular Biology. 15: 4631-4639. PMID 7623855  1
1994 Tye BK. The MCM2-3-5 proteins: are they replication licensing factors? Trends in Cell Biology. 4: 160-166. DOI: 10.1016/0962-8924(94)90200-3  1
1993 Liu Z, Frantz JD, Gilbert W, Tye BK. Identification and characterization of a nuclease activity specific for G4 tetrastranded DNA Proceedings of the National Academy of Sciences of the United States of America. 90: 3157-3161. PMID 8475054  1
1993 Yan H, Merchant AM, Tye BK. Cell cycle-regulated nuclear localization of MCM2 and MCM3, which are required for the initiation of DNA synthesis at chromosomal replication origins in yeast Genes and Development. 7: 2149-2160. PMID 8224843  1
1992 Chen Y, Hennessy KM, Botstein D, Tye BK. CDC46/MCM5, a yeast protein whose subcellular localization is cell cycle-regulated, is involved in DNA replication at autonomously replicating sequences. Proceedings of the National Academy of Sciences of the United States of America. 89: 10459-63. PMID 1438234 DOI: 10.1073/pnas.89.21.10459  1
1992 Elble R, Tye BK. Chromosome loss, hyperrecombination, and cell cycle arrest in a yeast mcm1 mutant Molecular Biology of the Cell. 3: 971-980. PMID 1421579  1
1991 Yan H, Gibson S, Tye BK. Mcm2 and Mcm37 two proteins important for ARS activity, are related in structure and function Genes and Development. 5: 944-957. PMID 2044961  1
1991 Liu Z, Tye BK. A yeast protein that binds to vertebrate telomeres and conserved yeast telomeric junctions Genes and Development. 5: 49-59. PMID 1989906  1
1991 Elble R, Tye BK. Both activation and repression of a-mating-type-specific genes in yeast require transcription factor Mcm1 Proceedings of the National Academy of Sciences of the United States of America. 88: 10966-10970. PMID 1961765  1
1991 Christ C, Tye BK. Functional domains of the yeast transcription/replication factor MCM1 Genes and Development. 5: 751-763. PMID 1851120  1
1990 Gibson SI, Surosky RT, Tye BK. The phenotype of the minichromosome maintenance mutant mcm3 is characteristic of mutants defective in DNA replication Molecular and Cellular Biology. 10: 5707-5720. PMID 2233713  1
1989 Walker SS, Francesconi SC, Tye BK, Eisenberg S. The OBF1 protein and its DNA-binding site are important for the function of an autonomously replicating sequence in Saccharomyces cerevisiae. Molecular and Cellular Biology. 9: 2914-21. PMID 2674674  1
1989 Passmore S, Elble R, Tye BK. A protein involved in minichromosome maintenance in yeast binds a transcriptional enhancer conserved in eukaryotes Genes &Amp; Development. 3: 921-935. PMID 2673922  1
1989 Surosky RT, Tye BK. Meiotic segregation of normal and deletion chromosomes in Saccharomyces cerevisiae Progress in Clinical and Biological Research. 311: 327-348. PMID 2672031  1
1988 Surosky RT, Tye BK. Meiotic disjunction of homologs in Saccharomyces cerevisiae is directed by pairing and recombination of the chromosome arms but not by pairing of the centromeres Genetics. 119: 273-287. PMID 3294102  1
1988 Eisenberg S, Civalier C, Tye BK. Specific interaction between a Saccharomyces cerevisiae protein and a DNA element associated with certain autonomously replicating sequences Proceedings of the National Academy of Sciences of the United States of America. 85: 743-746. PMID 3277180  1
1988 Passmore S, Maine GT, Elble R, Christ C, Tye BK. Saccharomyces cerevisiae protein involved in plasmid maintenance is necessary for mating of MATα cells Journal of Molecular Biology. 204: 593-606. PMID 3066908 DOI: 10.1016/0022-2836(88)90358-0  1
1987 Berman J, Eisenberg S, Tye BK. [32] An agarose gel electrophoresis assay for the detection of DNA-binding activities in yeast cell extracts Methods in Enzymology. 155: 528-537. PMID 3323822 DOI: 10.1016/0076-6879(87)55034-0  1
1987 Surosky RT, Tye BK. [14] Site-directed chromosomal rearrangements in yeast Methods in Enzymology. 153: 243-253. PMID 3323802 DOI: 10.1016/0076-6879(87)53057-9  1
1986 Tye BK, Sinha P, Surosky R, Gibson S, Maine G, Eisenberg S. Host factors in nuclear plasmid maintenance in Saccharomyces cerevisiae Basic Life Sciences. 40: 499-510. PMID 3551921  1
1986 Berman J, Tachibana CY, Tye BK. Identification of a telomere-binding activity from yeast Proceedings of the National Academy of Sciences of the United States of America. 83: 3713-3717. PMID 3520552  1
1986 Surosky RT, Newlon CS, Tye BK. The mitotic stability of deletion derivatives of chromosome III in yeast Proceedings of the National Academy of Sciences of the United States of America. 83: 414-418. PMID 3510434  1
1986 Sinha P, Chang V, Tye BK. A mutant that affects the function of autonomously replicating sequences in yeast Journal of Molecular Biology. 192: 805-814. PMID 3295255 DOI: 10.1016/0022-2836(86)90030-6  1
1985 Surosky RT, Tye BK. Construction of telocentric chromosomes in Saccharomyces cerevisiae Proceedings of the National Academy of Sciences of the United States of America. 82: 2106-2110. PMID 3885221  1
1985 Surosky RT, Tye BK. Resolution of dicentric chromosomes by TY-mediated recombination in yeast Genetics. 110: 397-419. PMID 2991081  1
1984 Walmsley RW, Chan CS, Tye BK, Petes TD. Unusual DNA sequences associated with the ends of yeast chromosomes. Nature. 310: 157-60. PMID 6377091 DOI: 10.1038/310157a0  1
1984 Maine GT, Surosky RT, Tye BK. Isolation and characterization of the centromere from chromosome V (CEN5) of Saccharomyces cerevisiae Molecular and Cellular Biology. 4: 86-91. PMID 6366514  1
1983 Chan CS, Tye BK. Organization of DNA sequences and replication origins at yeast telomeres. Cell. 33: 563-73. PMID 6345000 DOI: 10.1016/0092-8674(83)90437-3  1
1983 Chan CS, Tye BK. A family of Saccharomyces cerevisiae repetitive autonomously replicating sequences that have very similar genomic environments. Journal of Molecular Biology. 168: 505-23. PMID 6310122 DOI: 10.1016/S0022-2836(83)80299-X  1
1980 Chan CS, Tye BK. Autonomously replicating sequences in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 77: 6329-33. PMID 7005897  1
1979 Szostak JW, Stiles JI, Tye BK, Chiu P, Sherman F, Wu R. [29] Hybridization with synthetic oligonucleotides Methods in Enzymology. 68: 419-428. PMID 161605 DOI: 10.1016/0076-6879(79)68031-X  1
1975 Kleckner N, Chan RK, Tye BK, Botstein D. Mutagenesis by insertion of a drug-resistance element carrying an inverted repetition Journal of Molecular Biology. 97. PMID 1102715 DOI: 10.1016/S0022-2836(75)80059-3  0.4
1974 Tye BK, Chan RK, Botstein D. Packaging of an oversize transducing genome by Salmonella phage P22 Journal of Molecular Biology. 85. PMID 4853525 DOI: 10.1016/0022-2836(74)90311-8  0.4
1974 Tye BK, Huberman JA, Botstein D. Non-random circular permutation of phage P22 DNA. Journal of Molecular Biology. 85: 501-28. PMID 4853363 DOI: 10.1016/0022-2836(74)90312-X  0.4
1974 Young IT, Levinstone D, Eden M, Tye BK, Botstein D. Alignment of partial denaturation maps of circularly permuted DNA by computer Journal of Molecular Biology. 85: 528-532. PMID 4850477 DOI: 10.1016/0022-2836(74)90313-1  0.4
1974 Tye BK, Botstein D. P22 morphogenesis. II: Mechanism of DNA encapsulation Journal of Supramolecular Structure. 2: 225-238. PMID 4612248 DOI: 10.1002/jss.400020216  0.4
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