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Year Citation  Score
2016 Panda JJ, Yandrapu S, Kadam RS, Chauhan VS, Kompella UB. Retracted: Self-assembled Phenylalanine-α,β-dehydrophenylalanine Nanotubes for Sustained Intravitreal Delivery of a Multi-targeted Tyrosine Kinase Inhibitor. Journal of Controlled Release : Official Journal of the Controlled Release Society. 237: 186. PMID 27521264 DOI: 10.1016/j.jconrel.2016.07.039  0.6
2016 Muralidharan R, Babu A, Amreddy N, Basalingappa K, Mehta M, Chen A, Zhao YD, Kompella UB, Munshi A, Ramesh R. Folate receptor-targeted nanoparticle delivery of HuR-RNAi suppresses lung cancer cell proliferation and migration. Journal of Nanobiotechnology. 14: 47. PMID 27328938 DOI: 10.1186/s12951-016-0201-1  1
2015 Malik P, Kadam RS, Cheruvu NP, Kompella UB. Retraction of "Hydrophilic Prodrug Approach for Reduced Pigment Binding and Enhanced Transscleral Retinal Delivery of Celecoxib". Molecular Pharmaceutics. 12: 2558. PMID 26027478 DOI: 10.1021/acs.molpharmaceut.5b00366  1
2015 Wang Z, Cheng R, Lee K, Tyagi P, Ding L, Kompella UB, Chen J, Xu X, Ma JX. Nanoparticle-mediated expression of a Wnt pathway inhibitor ameliorates ocular neovascularization. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 855-64. PMID 25657312 DOI: 10.1161/ATVBAHA.114.304627  1
2015 Kadam RS, Ramamoorthy P, LaFlamme DJ, McKinsey TA, Kompella UB. Retraction of "Hypoxia Alters Ocular Drug Transporter Expression and Activity in Rat and Calf Models: Implications for Drug Delivery", Molecular Pharmaceutics. 12: 2559. DOI: 10.1021/acs.molpharmaceut.5b00367  1
2014 Kulkarni SS, Kompella UB. Potential drug delivery approaches for XFS-associated and XFS-associated glaucoma. Journal of Glaucoma. 23: S77-9. PMID 25275914 DOI: 10.1097/IJG.0000000000000109  1
2014 Clapp T, Munks MW, Trivedi R, Kompella UB, Braun LJ. Freeze-thaw stress of Alhydrogel ® alone is sufficient to reduce the immunogenicity of a recombinant hepatitis B vaccine containing native antigen. Vaccine. 32: 3765-71. PMID 24856785 DOI: 10.1016/j.vaccine.2014.05.037  1
2014 Rowe-Rendleman CL, Durazo SA, Kompella UB, Rittenhouse KD, Di Polo A, Weiner AL, Grossniklaus HE, Naash MI, Lewin AS, Horsager A, Edelhauser HF. Drug and gene delivery to the back of the eye: from bench to bedside. Investigative Ophthalmology & Visual Science. 55: 2714-30. PMID 24777644 DOI: 10.1167/iovs.13-13707  1
2014 Rajashekhar G, Shivanna M, Kompella UB, Wang Y, Srinivas SP. Role of MMP-9 in the breakdown of barrier integrity of the corneal endothelium in response to TNF-α. Experimental Eye Research. 122: 77-85. PMID 24667088 DOI: 10.1016/j.exer.2014.03.004  1
2014 Kim SJ, Toma H, Shah R, Kompella UB, Vooturi SK, Sheng J. The safety, pharmacokinetics, and efficacy of intraocular celecoxib. Investigative Ophthalmology & Visual Science. 55: 1409-18. PMID 24458149 DOI: 10.1167/iovs.13-13667  1
2014 Kulkarni SS, Kompella UB. Nanoparticles for drug and gene delivery in treating diseases of the eye Methods in Pharmacology and Toxicology. 291-316. DOI: 10.1007/7653-2013-11  1
2013 Yandrapu SK, Upadhyay AK, Petrash JM, Kompella UB. Nanoparticles in porous microparticles prepared by supercritical infusion and pressure quench technology for sustained delivery of bevacizumab. Molecular Pharmaceutics. 10: 4676-86. PMID 24131101 DOI: 10.1021/mp400487f  1
2013 Panda JJ, Yandrapu S, Kadam RS, Chauhan VS, Kompella UB. Self-assembled phenylalanine-α,β-dehydrophenylalanine nanotubes for sustained intravitreal delivery of a multi-targeted tyrosine kinase inhibitor. Journal of Controlled Release : Official Journal of the Controlled Release Society. 172: 1151-60. PMID 24075925 DOI: 10.1016/j.jconrel.2013.09.016  1
2013 Rao VR, Upadhyay AK, Kompella UB. pH shift assembly of adenoviral serotype 5 capsid protein nanosystems for enhanced delivery of nanoparticles, proteins and nucleic acids. Journal of Controlled Release : Official Journal of the Controlled Release Society. 172: 341-50. PMID 24004886 DOI: 10.1016/j.jconrel.2013.08.023  1
2013 Chowdhury S, Guha R, Trivedi R, Kompella UB, Konar A, Hazra S. Pirfenidone nanoparticles improve corneal wound healing and prevent scarring following alkali burn. Plos One. 8: e70528. PMID 23940587 DOI: 10.1371/journal.pone.0070528  1
2013 Tari SR, Youssif M, Samson CM, Harris RL, Lin CM, Kompella UB, Antonetti DA, Barile GR. Polychromatic angiography for the assessment of VEGF-induced BRB dysfunction in the rabbit retina. Investigative Ophthalmology & Visual Science. 54: 5550-8. PMID 23882687 DOI: 10.1167/iovs.13-12144  1
2013 Tyagi P, Barros M, Stansbury JW, Kompella UB. Light-activated, in situ forming gel for sustained suprachoroidal delivery of bevacizumab. Molecular Pharmaceutics. 10: 2858-67. PMID 23734705 DOI: 10.1021/mp300716t  1
2013 Kadam RS, Williams J, Tyagi P, Edelhauser HF, Kompella UB. Suprachoroidal delivery in a rabbit ex vivo eye model: influence of drug properties, regional differences in delivery, and comparison with intravitreal and intracameral routes. Molecular Vision. 19: 1198-210. PMID 23734089  1
2013 Bargagna-Mohan P, Deokule SP, Thompson K, Wizeman J, Srinivasan C, Vooturi S, Kompella UB, Mohan R. Withaferin A effectively targets soluble vimentin in the glaucoma filtration surgical model of fibrosis. Plos One. 8: e63881. PMID 23667686 DOI: 10.1371/journal.pone.0063881  1
2013 Baid R, Upadhyay AK, Shinohara T, Kompella UB. Biosynthesis, characterization, and efficacy in retinal degenerative diseases of lens epithelium-derived growth factor fragment (LEDGF1-326), a novel therapeutic protein. The Journal of Biological Chemistry. 288: 17372-83. PMID 23640891 DOI: 10.1074/jbc.M112.441618  1
2013 Kadam RS, Ramamoorthy P, LaFlamme DJ, McKinsey TA, Kompella UB. Hypoxia alters ocular drug transporter expression and activity in rat and calf models: implications for drug delivery. Molecular Pharmaceutics. 10: 2350-61. PMID 23607566 DOI: 10.1021/mp3007133  1
2013 Kompella UB, Amrite AC, Pacha Ravi R, Durazo SA. Nanomedicines for back of the eye drug delivery, gene delivery, and imaging. Progress in Retinal and Eye Research. 36: 172-98. PMID 23603534 DOI: 10.1016/j.preteyeres.2013.04.001  1
2013 Dhanda DS, Tyagi P, Mirvish SS, Kompella UB. Supercritical fluid technology based large porous celecoxib-PLGA microparticles do not induce pulmonary fibrosis and sustain drug delivery and efficacy for several weeks following a single dose. Journal of Controlled Release : Official Journal of the Controlled Release Society. 168: 239-50. PMID 23562638 DOI: 10.1016/j.jconrel.2013.03.027  1
2013 Kompella UB. Nanotechnology and drug delivery. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 29: 89. PMID 23485089 DOI: 10.1089/jop.2013.1504  1
2013 Luo L, Zhang X, Hirano Y, Tyagi P, Barabás P, Uehara H, Miya TR, Singh N, Archer B, Qazi Y, Jackman K, Das SK, Olsen T, Chennamaneni SR, Stagg BC, ... ... Kompella UB, et al. Targeted intraceptor nanoparticle therapy reduces angiogenesis and fibrosis in primate and murine macular degeneration. Acs Nano. 7: 3264-75. PMID 23464925 DOI: 10.1021/nn305958y  1
2013 Yandrapu S, Kompella UB. Development of sustained-release microspheres for the delivery of SAR 1118, an LFA-1 antagonist intended for the treatment of vascular complications of the eye. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 29: 236-48. PMID 23256487 DOI: 10.1089/jop.2012.0210  1
2013 Kadam RS, Vooturi SK, Kompella UB. Immunohistochemical and functional characterization of peptide, organic cation, neutral and basic amino acid, and monocarboxylate drug transporters in human ocular tissues. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 466-74. PMID 23169611 DOI: 10.1124/dmd.112.045674  1
2013 Aquilante CL, Kosmiski LA, Bourne DW, Bushman LR, Daily EB, Hammond KP, Hopley CW, Kadam RS, Kanack AT, Kompella UB, Le M, Predhomme JA, Rower JE, Sidhom MS. Impact of the CYP2C8 *3 polymorphism on the drug-drug interaction between gemfibrozil and pioglitazone. British Journal of Clinical Pharmacology. 75: 217-26. PMID 22625877 DOI: 10.1111/j.1365-2125.2012.04343.x  1
2012 Baltazar GC, Guha S, Lu W, Lim J, Boesze-Battaglia K, Laties AM, Tyagi P, Kompella UB, Mitchell CH. Acidic nanoparticles are trafficked to lysosomes and restore an acidic lysosomal pH and degradative function to compromised ARPE-19 cells. Plos One. 7: e49635. PMID 23272048 DOI: 10.1371/journal.pone.0049635  1
2012 Trivedi R, Redente EF, Thakur A, Riches DW, Kompella UB. Local delivery of biodegradable pirfenidone nanoparticles ameliorates bleomycin-induced pulmonary fibrosis in mice. Nanotechnology. 23: 505101. PMID 23186914 DOI: 10.1088/0957-4484/23/50/505101  1
2012 Tyagi P, Kadam RS, Kompella UB. Comparison of suprachoroidal drug delivery with subconjunctival and intravitreal routes using noninvasive fluorophotometry. Plos One. 7: e48188. PMID 23118950 DOI: 10.1371/journal.pone.0048188  1
2012 Kadam RS, Scheinman RI, Kompella UB. Pigmented-MDCK (P-MDCK) cell line with tunable melanin expression: an in vitro model for the outer blood-retinal barrier. Molecular Pharmaceutics. 9: 3228-35. PMID 23003570 DOI: 10.1021/mp300305f  1
2012 Vooturi SK, Kadam RS, Kompella UB. Transporter targeted gatifloxacin prodrugs: synthesis, permeability, and topical ocular delivery. Molecular Pharmaceutics. 9: 3136-46. PMID 23003105 DOI: 10.1021/mp300245r  1
2012 Yang H, Tyagi P, Kadam RS, Holden CA, Kompella UB. Hybrid dendrimer hydrogel/PLGA nanoparticle platform sustains drug delivery for one week and antiglaucoma effects for four days following one-time topical administration. Acs Nano. 6: 7595-606. PMID 22876910 DOI: 10.1021/nn301873v  1
2012 Tewari-Singh N, Jain AK, Inturi S, Ammar DA, Agarwal C, Tyagi P, Kompella UB, Enzenauer RW, Petrash JM, Agarwal R. Silibinin, dexamethasone, and doxycycline as potential therapeutic agents for treating vesicant-inflicted ocular injuries. Toxicology and Applied Pharmacology. 264: 23-31. PMID 22841772 DOI: 10.1016/j.taap.2012.07.014  1
2012 Kadam RS, Tyagi P, Edelhauser HF, Kompella UB. Influence of choroidal neovascularization and biodegradable polymeric particle size on transscleral sustained delivery of triamcinolone acetonide. International Journal of Pharmaceutics. 434: 140-7. PMID 22633904 DOI: 10.1016/j.ijpharm.2012.05.025  1
2012 Kadam RS, Bourne DW, Kompella UB. Nano-advantage in enhanced drug delivery with biodegradable nanoparticles: contribution of reduced clearance. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 1380-8. PMID 22498894 DOI: 10.1124/dmd.112.044925  1
2012 Qazi Y, Stagg B, Singh N, Singh S, Zhang X, Luo L, Simonis J, Kompella UB, Ambati BK. Nanoparticle-mediated delivery of shRNA.VEGF-a plasmids regresses corneal neovascularization. Investigative Ophthalmology & Visual Science. 53: 2837-44. PMID 22467572 DOI: 10.1167/iovs.11-9139  1
2012 Durairaj C, Chastain JE, Kompella UB. Intraocular distribution of melanin in human, monkey, rabbit, minipig and dog eyes. Experimental Eye Research. 98: 23-7. PMID 22440812 DOI: 10.1016/j.exer.2012.03.004  1
2012 Cho YK, Uehara H, Young JR, Tyagi P, Kompella UB, Zhang X, Luo L, Singh N, Archer B, Ambati BK. Flt23k nanoparticles offer additive benefit in graft survival and anti-angiogenic effects when combined with triamcinolone. Investigative Ophthalmology & Visual Science. 53: 2328-36. PMID 22427553 DOI: 10.1167/iovs.11-8393  1
2012 Malik P, Kadam RS, Cheruvu NP, Kompella UB. Hydrophilic prodrug approach for reduced pigment binding and enhanced transscleral retinal delivery of celecoxib. Molecular Pharmaceutics. 9: 605-14. PMID 22256989 DOI: 10.1021/mp2005164  1
2012 Durazo SA, Kompella UB. Functionalized nanosystems for targeted mitochondrial delivery. Mitochondrion. 12: 190-201. PMID 22138492 DOI: 10.1016/j.mito.2011.11.001  1
2012 Holden CA, Tyagi P, Thakur A, Kadam R, Jadhav G, Kompella UB, Yang H. Polyamidoamine dendrimer hydrogel for enhanced delivery of antiglaucoma drugs. Nanomedicine : Nanotechnology, Biology, and Medicine. 8: 776-83. PMID 21930109 DOI: 10.1016/j.nano.2011.08.018  1
2011 Shelke NB, Kadam R, Tyagi P, Rao VR, Kompella UB. Intravitreal Poly(L-lactide) Microparticles Sustain Retinal and Choroidal Delivery of TG-0054, a Hydrophilic Drug Intended for Neovascular Diseases. Drug Delivery and Translational Research. 1: 76-90. PMID 22888471 DOI: 10.1007/s13346-010-0009-8  1
2011 Scheinman RI, Trivedi R, Vermillion S, Kompella UB. Functionalized STAT1 siRNA nanoparticles regress rheumatoid arthritis in a mouse model. Nanomedicine (London, England). 6: 1669-82. PMID 22087799 DOI: 10.2217/nnm.11.90  1
2011 Thakur A, Scheinman RI, Rao VR, Kompella UB. Pazopanib, a multitargeted tyrosine kinase inhibitor, reduces diabetic retinal vascular leukostasis and leakage. Microvascular Research. 82: 346-50. PMID 21945644 DOI: 10.1016/j.mvr.2011.09.001  1
2011 Baid R, Scheinman RI, Shinohara T, Singh DP, Kompella UB. LEDGF(1-326) decreases P23H and wild type rhodopsin aggregates and P23H rhodopsin mediated cell damage in human retinal pigment epithelial cells. Plos One. 6: e24616. PMID 21915354 DOI: 10.1371/journal.pone.0024616  1
2011 Durazo SA, Kadam RS, Drechsel D, Patel M, Kompella UB. Brain mitochondrial drug delivery: influence of drug physicochemical properties. Pharmaceutical Research. 28: 2833-47. PMID 21796482 DOI: 10.1007/s11095-011-0532-4  1
2011 Vasireddy V, Chavali VR, Joseph VT, Kadam R, Lin JH, Jamison JA, Kompella UB, Reddy GB, Ayyagari R. Rescue of photoreceptor degeneration by curcumin in transgenic rats with P23H rhodopsin mutation. Plos One. 6: e21193. PMID 21738619 DOI: 10.1371/journal.pone.0021193  1
2011 Kadam RS, Jadhav G, Ogidigben M, Kompella UB. Ocular pharmacokinetics of dorzolamide and brinzolamide after single and multiple topical dosing: implications for effects on ocular blood flow. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 1529-37. PMID 21673129 DOI: 10.1124/dmd.111.040055  1
2011 Pan CK, Durairaj C, Kompella UB, Agwu O, Oliver SC, Quiroz-Mercado H, Mandava N, Olson JL. Comparison of long-acting bevacizumab formulations in the treatment of choroidal neovascularization in a rat model. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 27: 219-24. PMID 21574814 DOI: 10.1089/jop.2010.0158  1
2011 Thakur A, Kadam R, Kompella UB. Trabecular meshwork and lens partitioning of corticosteroids: implications for elevated intraocular pressure and cataracts. Archives of Ophthalmology (Chicago, Ill. : 1960). 129: 914-20. PMID 21402977 DOI: 10.1001/archophthalmol.2011.39  1
2011 Jin J, Zhou KK, Park K, Hu Y, Xu X, Zheng Z, Tyagi P, Kompella UB, Ma JX. Anti-inflammatory and antiangiogenic effects of nanoparticle-mediated delivery of a natural angiogenic inhibitor. Investigative Ophthalmology & Visual Science. 52: 6230-7. PMID 21357401 DOI: 10.1167/iovs.10-6229  1
2011 Thakur A, Kadam RS, Kompella UB. Influence of drug solubility and lipophilicity on transscleral retinal delivery of six corticosteroids. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 39: 771-81. PMID 21346004 DOI: 10.1124/dmd.110.037408  1
2011 Kadam RS, Cheruvu NP, Edelhauser HF, Kompella UB. Sclera-choroid-RPE transport of eight β-blockers in human, bovine, porcine, rabbit, and rat models. Investigative Ophthalmology & Visual Science. 52: 5387-99. PMID 21282583 DOI: 10.1167/iovs.10-6233  1
2011 Pfeifer T, Buchebner M, Chandak PG, Patankar J, Kratzer A, Obrowsky S, Rechberger GN, Kadam RS, Kompella UB, Kostner GM, Kratky D, Levak-Frank S. Synthetic LXR agonist suppresses endogenous cholesterol biosynthesis and efficiently lowers plasma cholesterol. Current Pharmaceutical Biotechnology. 12: 285-92. PMID 21190543  1
2010 Kompella UB, Kadam RS, Lee VH. Recent advances in ophthalmic drug delivery. Therapeutic Delivery. 1: 435-56. PMID 21399724 DOI: 10.4155/TDE.10.40  1
2010 Edelhauser HF, Rowe-Rendleman CL, Robinson MR, Dawson DG, Chader GJ, Grossniklaus HE, Rittenhouse KD, Wilson CG, Weber DA, Kuppermann BD, Csaky KG, Olsen TW, Kompella UB, Holers VM, Hageman GS, et al. Ophthalmic drug delivery systems for the treatment of retinal diseases: basic research to clinical applications. Investigative Ophthalmology & Visual Science. 51: 5403-20. PMID 20980702 DOI: 10.1167/iovs.10-5392  1
2010 Durairaj C, Kadam RS, Chandler JW, Hutcherson SL, Kompella UB. Nanosized dendritic polyguanidilyated translocators for enhanced solubility, permeability, and delivery of gatifloxacin. Investigative Ophthalmology & Visual Science. 51: 5804-16. PMID 20484584 DOI: 10.1167/iovs.10-5388  1
2010 Rao VR, Prescott E, Shelke NB, Trivedi R, Thomas P, Struble C, Gadek T, O'Neill CA, Kompella UB. Delivery of SAR 1118 to the retina via ophthalmic drops and its effectiveness in a rat streptozotocin (STZ) model of diabetic retinopathy (DR). Investigative Ophthalmology & Visual Science. 51: 5198-204. PMID 20445119 DOI: 10.1167/iovs.09-5144  1
2010 Trivedi R, Kompella UB. Nanomicellar formulations for sustained drug delivery: strategies and underlying principles. Nanomedicine (London, England). 5: 485-505. PMID 20394539 DOI: 10.2217/nnm.10.10  1
2010 Mayo AS, Ambati BK, Kompella UB. Gene delivery nanoparticles fabricated by supercritical fluid extraction of emulsions. International Journal of Pharmaceutics. 387: 278-85. PMID 20025945 DOI: 10.1016/j.ijpharm.2009.12.024  1
2010 Kadam RS, Kompella UB. Influence of lipophilicity on drug partitioning into sclera, choroid-retinal pigment epithelium, retina, trabecular meshwork, and optic nerve. The Journal of Pharmacology and Experimental Therapeutics. 332: 1107-20. PMID 19926800 DOI: 10.1124/jpet.109.161570  1
2010 Sunkara G, Ayalasomayajula SP, DeRuiter J, Kompella UB. Probenecid treatment enhances retinal and brain delivery of N-4-benzoylaminophenylsulfonylglycine: an anionic aldose reductase inhibitor. Brain Research Bulletin. 81: 327-32. PMID 19761819 DOI: 10.1016/j.brainresbull.2009.09.001  1
2009 Sundaram S, Trivedi R, Durairaj C, Ramesh R, Ambati BK, Kompella UB. Targeted drug and gene delivery systems for lung cancer therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 7299-308. PMID 19920099 DOI: 10.1158/1078-0432.CCR-09-1745  1
2009 Kang SJ, Durairaj C, Kompella UB, O'Brien JM, Grossniklaus HE. Subconjunctival nanoparticle carboplatin in the treatment of murine retinoblastoma. Archives of Ophthalmology (Chicago, Ill. : 1960). 127: 1043-7. PMID 19667343 DOI: 10.1001/archophthalmol.2009.185  1
2009 Barañano DE, Kim SJ, Edelhauser HF, Durairaj C, Kompella UB, Handa JT. Efficacy and pharmacokinetics of intravitreal non-steroidal anti-inflammatory drugs for intraocular inflammation. The British Journal of Ophthalmology. 93: 1387-90. PMID 19628498 DOI: 10.1136/bjo.2009.157297  1
2009 Sundaram S, Roy SK, Ambati BK, Kompella UB. Surface-functionalized nanoparticles for targeted gene delivery across nasal respiratory epithelium. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 3752-65. PMID 19608628 DOI: 10.1096/fj.09-129825  1
2009 Durairaj C, Kim SJ, Edelhauser HF, Shah JC, Kompella UB. Influence of dosage form on the intravitreal pharmacokinetics of diclofenac. Investigative Ophthalmology & Visual Science. 50: 4887-97. PMID 19516015 DOI: 10.1167/iovs.09-3565  1
2009 Sundaram S, Durairaj C, Kadam R, Kompella UB. Luteinizing hormone-releasing hormone receptor-targeted deslorelin-docetaxel conjugate enhances efficacy of docetaxel in prostate cancer therapy. Molecular Cancer Therapeutics. 8: 1655-65. PMID 19509261 DOI: 10.1158/1535-7163.MCT-08-0988  1
2009 Park K, Chen Y, Hu Y, Mayo AS, Kompella UB, Longeras R, Ma JX. Nanoparticle-mediated expression of an angiogenic inhibitor ameliorates ischemia-induced retinal neovascularization and diabetes-induced retinal vascular leakage. Diabetes. 58: 1902-13. PMID 19491211 DOI: 10.2337/db08-1327  1
2009 Ayalasomayajula SP, Ashton P, Kompella UB. Fluocinolone inhibits VEGF expression via glucocorticoid receptor in human retinal pigment epithelial (ARPE-19) cells and TNF-alpha-induced angiogenesis in chick chorioallantoic membrane (CAM). Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 25: 97-103. PMID 19284324 DOI: 10.1089/jop.2008.0090  1
2009 Kim ES, Durairaj C, Kadam RS, Lee SJ, Mo Y, Geroski DH, Kompella UB, Edelhauser HF. Human scleral diffusion of anticancer drugs from solution and nanoparticle formulation. Pharmaceutical Research. 26: 1155-61. PMID 19194787 DOI: 10.1007/s11095-009-9835-0  1
2009 Singh SR, Grossniklaus HE, Kang SJ, Edelhauser HF, Ambati BK, Kompella UB. Intravenous transferrin, RGD peptide and dual-targeted nanoparticles enhance anti-VEGF intraceptor gene delivery to laser-induced CNV. Gene Therapy. 16: 645-59. PMID 19194480 DOI: 10.1038/gt.2008.185  1
2009 Kadam RS, Kompella UB. Cassette analysis of eight beta-blockers in bovine eye sclera, choroid-RPE, retina, and vitreous by liquid chromatography-tandem mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 877: 253-60. PMID 19117816 DOI: 10.1016/j.jchromb.2008.12.027  1
2009 Sundaram S, Roy SK, Kompella UB. Differential expression of LHRH-receptor in bovine nasal tissue and its role in deslorelin delivery. Peptides. 30: 351-8. PMID 18992782 DOI: 10.1016/j.peptides.2008.10.005  1
2009 Cheruvu NP, Amrite AC, Kompella UB. Effect of diabetes on transscleral delivery of celecoxib. Pharmaceutical Research. 26: 404-14. PMID 18987961 DOI: 10.1007/s11095-008-9757-2  1
2009 Durairaj C, Shah JC, Senapati S, Kompella UB. Prediction of vitreal half-life based on drug physicochemical properties: quantitative structure-pharmacokinetic relationships (QSPKR). Pharmaceutical Research. 26: 1236-60. PMID 18841448 DOI: 10.1007/s11095-008-9728-7  1
2009 Kratzer A, Buchebner M, Pfeifer T, Becker TM, Uray G, Miyazaki M, Miyazaki-Anzai S, Ebner B, Chandak PG, Kadam RS, Calayir E, Rathke N, Ahammer H, Radovic B, Trauner M, ... ... Kompella UB, et al. Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia. Journal of Lipid Research. 50: 312-26. PMID 18812595 DOI: 10.1194/jlr.M800376-JLR200  1
2009 Durairaj C, Kompella UB. Dendritic polyguanidilyated translocators for ocular drug delivery Drug Delivery Technology. 9: 36-43.  1
2008 Amrite AC, Edelhauser HF, Singh SR, Kompella UB. Effect of circulation on the disposition and ocular tissue distribution of 20 nm nanoparticles after periocular administration. Molecular Vision. 14: 150-60. PMID 18334929  1
2008 Christie JG, Kompella UB. Ophthalmic light sensitive nanocarrier systems. Drug Discovery Today. 13: 124-34. PMID 18275910 DOI: 10.1016/j.drudis.2007.12.005  1
2008 Cheruvu NP, Amrite AC, Kompella UB. Effect of eye pigmentation on transscleral drug delivery. Investigative Ophthalmology & Visual Science. 49: 333-41. PMID 18172110 DOI: 10.1167/iovs.07-0214  1
2008 Amrite AC, Edelhauser HF, Kompella UB. Modeling of corneal and retinal pharmacokinetics after periocular drug administration. Investigative Ophthalmology & Visual Science. 49: 320-32. PMID 18172109 DOI: 10.1167/iovs.07-0593  1
2008 Amrite AC, Kompella UB. Celecoxib inhibits proliferation of retinal pigment epithelial and choroid-retinal endothelial cells by a cyclooxygenase-2-independent mechanism. The Journal of Pharmacology and Experimental Therapeutics. 324: 749-58. PMID 18032574 DOI: 10.1124/jpet.107.128918  1
2007 Kompella UB. Drug delivery to the back of the eye Archivos De La Sociedad Espanola De Oftalmologia. 82: 669-670. PMID 17979032  1
2007 Mo Y, Barnett ME, Takemoto D, Davidson H, Kompella UB. Human serum albumin nanoparticles for efficient delivery of Cu, Zn superoxide dismutase gene. Molecular Vision. 13: 746-57. PMID 17563725  1
2007 Raghava S, Kompella UB. AQ4, an antitumor anthracenedione, inhibits endothelial cell proliferation and vascular endothelial growth factor secretion: implications for the therapy of ocular neovascular disorders. European Journal of Pharmacology. 568: 68-74. PMID 17543940 DOI: 10.1016/j.ejphar.2007.04.044  1
2007 Jani PD, Singh N, Jenkins C, Raghava S, Mo Y, Amin S, Kompella UB, Ambati BK. Nanoparticles sustain expression of Flt intraceptors in the cornea and inhibit injury-induced corneal angiogenesis. Investigative Ophthalmology & Visual Science. 48: 2030-6. PMID 17460257 DOI: 10.1167/iovs.06-0853  1
2007 Kador PF, Randazzo J, Babb T, Koushik K, Takamura Y, Zhu W, Blessing K, Kompella UB. Topical aldose reductase inhibitor formulations for effective lens drug delivery in a rat model for sugar cataracts. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. 23: 116-23. PMID 17444799 DOI: 10.1089/jop.2006.0112  1
2007 Marra M, Gukasyan HJ, Raghava S, Kompella UB. 2nd Ophthalmic Drug Development and Delivery Summit. Expert Opinion On Drug Delivery. 4: 77-85. PMID 17184164 DOI: 10.1517/17425247.4.1.77  1
2006 Kompella UB, Sundaram S, Raghava S, Escobar ER. Luteinizing hormone-releasing hormone agonist and transferrin functionalizations enhance nanoparticle delivery in a novel bovine ex vivo eye model. Molecular Vision. 12: 1185-98. PMID 17102798  1
2006 Cheruvu NP, Kompella UB. Bovine and porcine transscleral solute transport: influence of lipophilicity and the Choroid-Bruch's layer. Investigative Ophthalmology & Visual Science. 47: 4513-22. PMID 17003447 DOI: 10.1167/iovs.06-0404  1
2006 Margalit E, Kugler LJ, Brumm MV, Meza JL, Kompella UB, Escobar ER, Christensen GR. The safety of intraocular ketorolac in rabbits. Investigative Ophthalmology & Visual Science. 47: 2093-9. PMID 16639020 DOI: 10.1167/iovs.05-0764  1
2006 Amrite AC, Ayalasomayajula SP, Cheruvu NP, Kompella UB. Single periocular injection of celecoxib-PLGA microparticles inhibits diabetes-induced elevations in retinal PGE2, VEGF, and vascular leakage. Investigative Ophthalmology & Visual Science. 47: 1149-60. PMID 16505053 DOI: 10.1167/iovs.05-0531  1
2005 Amrite AC, Kompella UB. Size-dependent disposition of nanoparticles and microparticles following subconjunctival administration. The Journal of Pharmacy and Pharmacology. 57: 1555-63. PMID 16354399 DOI: 10.1211/jpp.57.12.0005  1
2005 Bandi N, Ayalasomayajula SP, Dhanda DS, Iwakawa J, Cheng PW, Kompella UB. Intratracheal budesonide-poly(lactide-co-glycolide) microparticles reduce oxidative stress, VEGF expression, and vascular leakage in a benzo(a)pyrene-fed mouse model. The Journal of Pharmacy and Pharmacology. 57: 851-60. PMID 15969944 DOI: 10.1211/0022357056334  1
2005 Ayalasomayajula SP, Kompella UB. Subconjunctivally administered celecoxib-PLGA microparticles sustain retinal drug levels and alleviate diabetes-induced oxidative stress in a rat model. European Journal of Pharmacology. 511: 191-8. PMID 15792788 DOI: 10.1016/j.ejphar.2005.02.019  1
2005 Dhanda DS, Kompella UB. Metered dose inhalers (MDIs) and dry powder inhalers (DPIs) for pulmonary drug delivery: CMC issues Clinical Research and Regulatory Affairs. 22: 31-55. DOI: 10.1081/CRP-200062268  1
2004 Raghava S, Hammond M, Kompella UB. Periocular routes for retinal drug delivery. Expert Opinion On Drug Delivery. 1: 99-114. PMID 16296723 DOI: 10.1517/17425247.1.1.99  1
2004 Ayalasomayajula SP, Kompella UB. Retinal delivery of celecoxib is several-fold higher following subconjunctival administration compared to systemic administration. Pharmaceutical Research. 21: 1797-804. PMID 15553225 DOI: 10.1023/B:PHAM.0000045231.51924.e8  1
2004 Bandi N, Wei W, Roberts CB, Kotra LP, Kompella UB. Preparation of budesonide- and indomethacin-hydroxypropyl-beta-cyclodextrin (HPBCD) complexes using a single-step, organic-solvent-free supercritical fluid process. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 23: 159-68. PMID 15451004 DOI: 10.1016/j.ejps.2004.06.007  1
2004 Ayalasomayajula SP, Amrite AC, Kompella UB. Inhibition of cyclooxygenase-2, but not cyclooxygenase-1, reduces prostaglandin E2 secretion from diabetic rat retinas. European Journal of Pharmacology. 498: 275-8. PMID 15364005 DOI: 10.1016/j.ejphar.2004.07.046  1
2004 Koushik K, Dhanda DS, Cheruvu NP, Kompella UB. Pulmonary delivery of deslorelin: large-porous PLGA particles and HPbetaCD complexes. Pharmaceutical Research. 21: 1119-26. PMID 15290850 DOI: 10.1023/B:PHAM.0000032997.96823.88  1
2004 Koushik KN, Kompella UB. Transport of deslorelin, an LHRH agonist, is vectorial and exhibits regional variation in excised bovine nasal tissue. The Journal of Pharmacy and Pharmacology. 56: 861-8. PMID 15233864 DOI: 10.1211/0022357023646  1
2004 Koushik K, Bandi N, Sundaram S, Kompella UB. Evidence for LHRH-receptor expression in human airway epithelial (Calu-3) cells and its role in the transport of an LHRH agonist. Pharmaceutical Research. 21: 1034-46. PMID 15212170 DOI: 10.1023/B:PHAM.0000029294.70707.74  1
2004 Koushik K, Kompella UB. Preparation of large porous deslorelin-PLGA microparticles with reduced residual solvent and cellular uptake using a supercritical carbon dioxide process. Pharmaceutical Research. 21: 524-35. PMID 15070105 DOI: 10.1023/B:PHAM.0000019308.25479.a4  1
2004 Sunkara G, Ayalasomayajula SP, Rao CS, Vennerstrom JL, DeRuiter J, Kompella UB. Systemic and ocular pharmacokinetics of N-4-benzoylaminophenylsulfonylglycine (BAPSG), a novel aldose reductase inhibitor. The Journal of Pharmacy and Pharmacology. 56: 351-8. PMID 15025860 DOI: 10.1211/0022357022908  1
2004 Tammara VK, Kompella UB. Implantable microchip approval, flu vaccine shortage, and Vioxx® withdrawal Clinical Research and Regulatory Affairs. 21: 97-99. DOI: 10.1081/CRP-200044141  1
2004 Amrite AC, Cheruvu NPS, Sundaram S, Aravalli RN, Cheng PW, Kompella UB. Lung gene therapy: Clinical and regulatory issues Clinical Research and Regulatory Affairs. 21: 1-28. DOI: 10.1081/CRP-120039559  1
2004 Sundaram S, Bontha S, Koushik K, Kompella UB. Nasal and pulmonary delivery of deslorrelin, a peptide drug American Pharmaceutical Review. 7: 130-139.  1
2004 Tammara VK, Kompella UB. Clinical research and regulatory affairs: Editorial Clinical Research and Regulatory Affairs. 21.  1
2003 Aukunuru JV, Ayalasomayajula SP, Kompella UB. Nanoparticle formulation enhances the delivery and activity of a vascular endothelial growth factor antisense oligonucleotide in human retinal pigment epithelial cells. The Journal of Pharmacy and Pharmacology. 55: 1199-206. PMID 14604462 DOI: 10.1211/0022357021701  1
2003 Koushik K, Sunkara G, Gwilt P, Kompella UB. Pathways and kinetics of deslorelin degradation in an airway epithelial cell line (Calu-1). Pharmaceutical Research. 20: 779-87. PMID 12751634 DOI: 10.1023/A:1023489620394  1
2003 Kompella UB, Bandi N, Ayalasomayajula SP. Subconjunctival nano- and microparticles sustain retinal delivery of budesonide, a corticosteroid capable of inhibiting VEGF expression. Investigative Ophthalmology & Visual Science. 44: 1192-201. PMID 12601049 DOI: 10.1167/iovs.02-0791  1
2003 Ayalasomayajula SP, Kompella UB. Celecoxib, a selective cyclooxygenase-2 inhibitor, inhibits retinal vascular endothelial growth factor expression and vascular leakage in a streptozotocin-induced diabetic rat model. European Journal of Pharmacology. 458: 283-9. PMID 12504784 DOI: 10.1016/S0014-2999(02)02793-0  1
2002 Martin TM, Bandi N, Shulz R, Roberts CB, Kompella UB. Preparation of budesonide and budesonide-PLA microparticles using supercritical fluid precipitation technology. Aaps Pharmscitech. 3: E18. PMID 12916933 DOI: 10.1208/pt030318  1
2002 Zhang L, Parsons DL, Navarre C, Kompella UB. Development and in-vitro evaluation of sustained release poloxamer 407 (P407) gel formulations of ceftiofur. Journal of Controlled Release : Official Journal of the Controlled Release Society. 85: 73-81. PMID 12480313 DOI: 10.1016/S0168-3659(02)00273-0  1
2002 Wenzel JG, Balaji KS, Koushik K, Navarre C, Duran SH, Rahe CH, Kompella UB. Pluronic F127 gel formulations of deslorelin and GnRH reduce drug degradation and sustain drug release and effect in cattle. Journal of Controlled Release : Official Journal of the Controlled Release Society. 85: 51-9. PMID 12480311  1
2002 Ayalasomayajula SP, Kompella UB. Induction of vascular endothelial growth factor by 4-hydroxynonenal and its prevention by glutathione precursors in retinal pigment epithelial cells. European Journal of Pharmacology. 449: 213-20. PMID 12167462 DOI: 10.1016/S0014-2999(02)02043-5  1
2002 Aukunuru JV, Sunkara G, Ayalasomayajula SP, DeRuiter J, Clark RC, Kompella UB. A biodegradable injectable implant sustains systemic and ocular delivery of an aldose reductase inhibitor and ameliorates biochemical changes in a galactose-fed rat model for diabetic complications. Pharmaceutical Research. 19: 278-85. PMID 11934234 DOI: 10.1023/A:1014438800893  1
2002 Bandi N, Kompella UB. Budesonide reduces multidrug resistance-associated protein 1 expression in an airway epithelial cell line (Calu-1). European Journal of Pharmacology. 437: 9-17. PMID 11864633 DOI: 10.1016/S0014-2999(02)01267-0  1
2002 Wenzel JGW, Balaji KSS, Koushik K, Navarre C, Duran SH, Rahe CH, Kompella UB. Pluronic® F127 gel formulations of deslorelin and GnRH reduce drug degradation and sustain drug release and effect in cattle Journal of Controlled Release. 85: 51-59. DOI: 10.1016/S0168-3659(02)00271-7  1
2001 Sunkara G, Kompella UB. Controlled release of bioactive materials--28th international symposium. Carbohydrate drug carriers: cyclodextrins and chitosans. Idrugs : the Investigational Drugs Journal. 4: 1014-6. PMID 15965845  1
2001 Koushik KN, Bandi N, Kompella UB. Interaction of [D-Trp6, Des-Gly10] LHRH ethylamide and hydroxy propyl beta-cyclodextrin (HPbetaCD): thermodynamics of interaction and protection from degradation by alpha-chymotrypsin. Pharmaceutical Development and Technology. 6: 595-606. PMID 11775960 DOI: 10.1081/PDT-120000297  1
2001 Bandi N, Kompella UB. Budesonide reduces vascular endothelial growth factor secretion and expression in airway (Calu-1) and alveolar (A549) epithelial cells. European Journal of Pharmacology. 425: 109-16. PMID 11502275 DOI: 10.1016/S0014-2999(01)01192-X  1
2001 Aukunuru JV, Sunkara G, Bandi N, Thoreson WB, Kompella UB. Expression of multidrug resistance-associated protein (MRP) in human retinal pigment epithelial cells and its interaction with BAPSG, a novel aldose reductase inhibitor. Pharmaceutical Research. 18: 565-72. PMID 11465409 DOI: 10.1023/A:1011060705599  1
2001 Kompella UB, Koushik K. Preparation of drug delivery systems using supercritical fluid technology. Critical Reviews in Therapeutic Drug Carrier Systems. 18: 173-99. PMID 11325031  1
2001 Kompella UB, Lee VHL. Delivery systems for penetration enhancement of peptide and protein drugs: Design considerations Advanced Drug Delivery Reviews. 46: 211-245. PMID 11259842 DOI: 10.1016/S0169-409X(00)00137-X  0.36
2000 Ayalasomayajula SP, Kompella UB. Drug efflux pumps: challenges and opportunities. 14-18 November 1999, New Orleans, LA, USA. Idrugs : the Investigational Drugs Journal. 3: 148-9. PMID 16107925  1
2000 Sunkara G, Deruiter J, Clark CR, Kompella UB. In-vitro hydrolysis, permeability, and ocular uptake of prodrugs of N-[4-(benzoylamino)phenylsulfonyl]glycine, a novel aldose reductase inhibitor. The Journal of Pharmacy and Pharmacology. 52: 1113-22. PMID 11045892  1
2000 Aukunuru JV, Kompella UB, Betageri GV. Simultaneous high performance liquid chromatographic analysis of acetaminophen, salicylamide, phenyltoloxamine, and related products Journal of Liquid Chromatography and Related Technologies. 23: 565-578. DOI: 10.1081/JLC-100101473  1
1999 Kompella UB, Sunkara G, Thomas E, Clark CR, Deruiter J. Rabbit corneal and conjunctival permeability of the novel aldose reductase inhibitors: N-[[4-(benzoylamino)phenyl] sulphonyl]glycines and N-benzoyl-N-phenylglycines. The Journal of Pharmacy and Pharmacology. 51: 921-7. PMID 10504031 DOI: 10.1211/0022357991773357  1
1999 Sunkara G, Navarre CB, Kompella UB. Influence of pH and temperature on kinetics of ceftiofur degradation in aqueous solutions. The Journal of Pharmacy and Pharmacology. 51: 249-55. PMID 10344624  1
1999 Navarre CB, Zhang L, Sunkara G, Duran SH, Kompella UB. Ceftiofur distribution in plasma and joint fluid following regional limb injection in cattle. Journal of Veterinary Pharmacology and Therapeutics. 22: 13-9. PMID 10211712 DOI: 10.1046/j.1365-2885.1999.00186.x  1
1999 Kompella UB. Disposition of non-viral gene delivery systems and oligonucleotides Idrugs. 2: 31-32.  1
1999 Kompella UB. Drug delivery applications of supercritical fluid technology Idrugs. 2: 33-34.  1
1999 Kompella UB, Aukunuru JV, Betageri GV. Effect of neutral liposomes on corneal and conjunctival transport of didanosine Drug Delivery: Journal of Delivery and Targeting of Therapeutic Agents. 6: 9-14.  1
1998 Dani BA, Kompella UB. Inhibition of corneal metabolism of deslorelin by EDTA and ZnCl2 Drug Development and Industrial Pharmacy. 24: 11-17. PMID 15605592  1
1998 Mathison S, Nagilla R, Kompella UB. Nasal route for direct delivery of solutes to the central nervous system: fact or fiction? Journal of Drug Targeting. 5: 415-41. PMID 9783675 DOI: 10.3109/10611869808997870  1
1998 Kompella UB, Katragadda AK, Aukunuru JV, Betageri GV. Effect of liposomal charge on stavudine transport across rabbit cornea and conjunctiva Pharmacy and Pharmacology Communications. 4: 339-343.  1
1997 Kompella UB, Dani BA. Metabolism of [des-Gly10, D-Trp6]LHRH ethylamide in the rabbit conjunctiva Journal of Ocular Pharmacology and Therapeutics. 13: 163-170. PMID 9090616  1
1996 Kompella UB, Kim KJ, Shiue MHI, Lee VHL. Cyclic AMP modulation of active ion transport in the pigmented rabbit conjunctiva Journal of Ocular Pharmacology and Therapeutics. 12: 281-287. PMID 8875334  0.36
1996 Hosoya KI, Kompella UB, Kim KJ, Lee VHL. Contribution of Na+-glucose cotransport to the short-circuit current in the pigmented rabbit conjunctiva Current Eye Research. 15: 447-451. PMID 8670745  0.36
1996 Kompella UB, Dani BA. Metabolism of [Des-Gly10, D-Trp6]LHRH ethylamide in rabbit nasal tissue Life Sciences. 58: 2201-2207. PMID 8649206 DOI: 10.1016/0024-3205(96)00214-7  1
1995 Kompella UB, Kim KJ, Shiue MH, Lee VH. Possible existence of Na(+)-coupled amino acid transport in the pigmented rabbit conjunctiva. Life Sciences. 57: 1427-31. PMID 7674833 DOI: 10.1016/0024-3205(95)02105-R  0.36
1993 Kompella UB, Kim KJ, Lee VHL. Active chloride transport in the pigmented rabbit conjunctiva Current Eye Research. 12: 1041-1048. PMID 7511088 DOI: 10.3109/02713689309033501  0.36
1991 Lee VHL, Yamamoto A, Kompella UB. Mucosal penetration enhancers for facilitation of peptide and protein drug absorption Critical Reviews in Therapeutic Drug Carrier Systems. 8: 91-192. PMID 1934087  0.36
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