Francisco Lopera, M.D. - Publications

Affiliations: 
Neurosciences University Of Antioquia 
Area:
Alzheimer, Dementias

230 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Sepulveda-Falla D, Vélez JI, Acosta-Baena N, Baena A, Moreno S, Krasemann S, Lopera F, Mastronardi CA, Arcos-Burgos M. Genetic modifiers of cognitive decline in PSEN1 E280A Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38450831 DOI: 10.1002/alz.13754  0.733
2024 Almeida MC, Eger SJ, He C, Audouard M, Nikitina A, Glasauer SMK, Han D, Mejía-Cupajita B, Acosta-Uribe J, Villalba-Moreno ND, Littau JL, Elcheikhali M, Rivera EK, Carrettiero DC, Villegas-Lanau CA, ... ... Lopera F, et al. Single-nucleus RNA sequencing demonstrates an autosomal dominant Alzheimer's disease profile and possible mechanisms of disease protection. Neuron. PMID 38417436 DOI: 10.1016/j.neuron.2024.02.009  0.739
2023 Millar PR, Gordon BA, Wisch JK, Schultz SA, Benzinger TL, Cruchaga C, Hassenstab JJ, Ibanez L, Karch C, Llibre-Guerra JJ, Morris JC, Perrin RJ, Supnet-Bell C, Xiong C, Allegri RF, ... ... Lopera F, et al. Advanced structural brain aging in preclinical autosomal dominant Alzheimer disease. Molecular Neurodegeneration. 18: 98. PMID 38111006 DOI: 10.1186/s13024-023-00688-3  0.314
2023 Nelson MR, Liu P, Agrawal A, Yip O, Blumenfeld J, Traglia M, Kim MJ, Koutsodendris N, Rao A, Grone B, Hao Y, Yoon SY, Xu Q, De Leon S, Choenyi T, ... ... Lopera F, et al. The APOE-R136S mutation protects against APOE4-driven Tau pathology, neurodegeneration and neuroinflammation. Nature Neuroscience. PMID 37957317 DOI: 10.1038/s41593-023-01480-8  0.325
2023 Marino C, Perez-Corredor P, O'Hare M, Heuer A, Chmielewska N, Gordon H, Chandrahas AS, Gonzalez-Buendia L, Delgado-Tirado S, Doan TH, Vanderleest TE, Arevalo-Alquichire S, Obar RA, Ortiz-Cordero C, Villegas A, ... ... Lopera F, et al. APOE Christchurch-mimetic therapeutic antibody reduces APOE-mediated toxicity and tau phosphorylation. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37791598 DOI: 10.1002/alz.13436  0.703
2023 Wagemann O, Li Y, Hassenstab J, Aschenbrenner AJ, McKay NS, Gordon BA, Benzinger TLS, Xiong C, Cruchaga C, Renton AE, Perrin RJ, Berman SB, Chhatwal JP, Farlow MR, Day GS, ... ... Lopera F, et al. Investigation of sex differences in mutation carriers of the Dominantly Inherited Alzheimer Network. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37740921 DOI: 10.1002/alz.13460  0.377
2023 Ramos C, Madrigal C, Aguirre-Acevedo DC, Giraldo-Chica M, Acosta-Baena N, Aponte C, Aguillón D, Gómez M, Espinosa A, Madrigal L, Uribe C, Saldarriaga A, Alzate D, Ruiz A, Andrade A, ... ... Lopera F, et al. Psychological Status of the Participants in Alzheimer's Prevention Initiative Autosomal Dominant Alzheimer's Disease Colombia. Journal of Alzheimer's Disease : Jad. PMID 37638430 DOI: 10.3233/JAD-220941  0.371
2023 Langella S, Barksdale NG, Vasquez D, Aguillon D, Chen Y, Su Y, Acosta-Baena N, Acosta-Uribe J, Baena AY, Garcia-Ospina G, Giraldo-Chica M, Tirado V, Muñoz C, Ríos-Romenets S, Guzman-Martínez C, ... ... Lopera F, et al. Effect of apolipoprotein genotype and educational attainment on cognitive function in autosomal dominant Alzheimer's disease. Nature Communications. 14: 5120. PMID 37612284 DOI: 10.1038/s41467-023-40775-z  0.328
2023 Gomez-Sequeda N, Mendivil-Perez M, Jimenez-Del-Rio M, Lopera F, Velez-Pardo C. Cholinergic-like neurons and cerebral spheroids bearing the PSEN1 p.Ile416Thr variant mirror Alzheimer's disease neuropathology. Scientific Reports. 13: 12833. PMID 37553376 DOI: 10.1038/s41598-023-39630-4  0.305
2023 Lopera F, Custodio N, Rico-Restrepo M, Allegri RF, Barrientos JD, Garcia Batres E, Calandri IL, Calero Moscoso C, Caramelli P, Duran Quiroz JC, Jansen AM, Mimenza Alvarado AJ, Nitrini R, Parodi JF, Ramos C, et al. A task force for diagnosis and treatment of people with Alzheimer's disease in Latin America. Frontiers in Neurology. 14: 1198869. PMID 37497015 DOI: 10.3389/fneur.2023.1198869  0.309
2023 Vila-Castelar C, Chen Y, Langella S, Lopera F, Zetterberg H, Hansson O, Dage JL, Janelidzde S, Su Y, Chen K, Pluim McDowell C, Martinez JE, Ramirez-Gomez L, Garcia G, Aguillon D, et al. Sex differences in blood biomarkers and cognitive performance in individuals with autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37279390 DOI: 10.1002/alz.13314  0.402
2023 Lopera F, Marino C, Chandrahas AS, O'Hare M, Villalba-Moreno ND, Aguillon D, Baena A, Sanchez JS, Vila-Castelar C, Ramirez Gomez L, Chmielewska N, Oliveira GM, Littau JL, Hartmann K, Park K, et al. Resilience to autosomal dominant Alzheimer's disease in a Reelin-COLBOS heterozygous man. Nature Medicine. PMID 37188781 DOI: 10.1038/s41591-023-02318-3  0.768
2023 Yucebas D, Fox-Fuller JT, Badillo Cabrera A, Baena A, Pluim McDowell C, Aduen P, Vila-Castelar C, Bocanegra Y, Tirado V, Sanchez JS, Cronin-Golomb A, Lopera F, Quiroz YT. Associations of category fluency clustering performance with brain pathology in autosomal dominant Alzheimer's disease. Journal of the International Neuropsychological Society : Jins. 1-7. PMID 37185154 DOI: 10.1017/S1355617723000243  0.351
2023 Cochran JN, Acosta-Uribe J, Esposito BT, Madrigal L, Aguillón D, Giraldo MM, Taylor JW, Bradley J, Fulton-Howard B, Andrews SJ, Acosta-Baena N, Alzate D, Garcia GP, Piedrahita F, Lopez HE, ... ... Lopera F, et al. Genetic associations with age at dementia onset in the PSEN1 E280A Colombian kindred. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36951251 DOI: 10.1002/alz.13021  0.329
2023 Maestre G, Carrillo M, Kalaria R, Acosta D, Adams L, Adoukonou T, Akinwande K, Akinyemi J, Akinyemi R, Akpa O, Alladi S, Allegri R, Arizaga R, Arshad F, Arulogun O, ... ... Lopera F, et al. The Nairobi Declaration-Reducing the burden of dementia in low- and middle-income countries (LMICs): Declaration of the 2022 Symposium on Dementia and Brain Aging in LMICs. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36905253 DOI: 10.1002/alz.13025  0.671
2023 Acosta-Baena N, Lopera-Gómez CM, Jaramillo-Elorza MC, Velilla-Jiménez L, Villegas-Lanau CA, Sepúlveda-Falla D, Arcos-Burgos M, Lopera F. Early Depressive Symptoms Predict Faster Dementia Progression in Autosomal-Dominant Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 36847011 DOI: 10.3233/JAD-221294  0.711
2022 Bubak AN, Merle L, Niemeyer CS, Baxter BD, Gentile Polese A, Ramakrishnan V, Gomez J, Madrigal L, Villegas-Lanau A, Lopera F, Macklin W, Frietze S, Nagel MA, Restrepo D. Signatures for viral infection and inflammation in the proximal olfactory system in familial Alzheimer's disease. Neurobiology of Aging. 123: 75-82. PMID 36638683 DOI: 10.1016/j.neurobiolaging.2022.12.004  0.311
2022 Maito MA, Santamaría-García H, Moguilner S, Possin KL, Godoy ME, Avila-Funes JA, Behrens MI, Brusco IL, Bruno MA, Cardona JF, Custodio N, García AM, Javandel S, Lopera F, Matallana DL, et al. Classification of Alzheimer's disease and frontotemporal dementia using routine clinical and cognitive measures across multicentric underrepresented samples: A cross sectional observational study. Lancet Regional Health. Americas. 17. PMID 36583137 DOI: 10.1016/j.lana.2022.100387  0.339
2022 Aguillon D, Langella S, Chen Y, Sanchez JS, Su Y, Vila-Castelar C, Vasquez D, Zetterberg H, Hansson O, Dage JL, Janelidze S, Chen K, Fox-Fuller JT, Aduen P, Martinez JE, ... ... Lopera F, et al. Plasma p-tau217 predicts in vivo brain pathology and cognition in autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36571821 DOI: 10.1002/alz.12906  0.353
2022 Reiman EM, Pruzin JJ, Rios-Romenets S, Brown C, Giraldo M, Acosta-Baena N, Tobon C, Hu N, Chen Y, Ghisays V, Enos J, Goradia DD, Lee W, Luo J, Malek-Ahmadi M, ... ... Lopera F, et al. A public resource of baseline data from the Alzheimer's Prevention Initiative Autosomal-Dominant Alzheimer's Disease Trial. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36373344 DOI: 10.1002/alz.12843  0.378
2022 Henao-Restrepo J, López-Murillo C, Valderrama-Carmona P, Orozco-Santa N, Gomez J, Gutiérrez-Vargas J, Moraga R, Toledo J, Littau JL, Härtel S, Arboleda-Velásquez JF, Sepulveda-Falla D, Lopera F, Cardona-Gómez GP, Villegas A, et al. Gliovascular alterations in sporadic and familial Alzheimer's disease: APOE3 Christchurch homozygote glioprotection. Brain Pathology (Zurich, Switzerland). e13119. PMID 36130084 DOI: 10.1111/bpa.13119  0.739
2022 Sepulveda-Falla D, Sanchez JS, Almeida MC, Boassa D, Acosta-Uribe J, Vila-Castelar C, Ramirez-Gomez L, Baena A, Aguillon D, Villalba-Moreno ND, Littau JL, Villegas A, Beach TG, White CL, Ellisman M, ... ... Lopera F, et al. Distinct tau neuropathology and cellular profiles of an APOE3 Christchurch homozygote protected against autosomal dominant Alzheimer's dementia. Acta Neuropathologica. PMID 35838824 DOI: 10.1007/s00401-022-02467-8  0.757
2022 Schoemaker D, Zanon Zotin MC, Chen K, Igwe KC, Vila-Castelar C, Martinez J, Baena A, Fox-Fuller JT, Lopera F, Reiman EM, Brickman AM, Quiroz YT. White matter hyperintensities are a prominent feature of autosomal dominant Alzheimer's disease that emerge prior to dementia. Alzheimer's Research & Therapy. 14: 89. PMID 35768838 DOI: 10.1186/s13195-022-01030-7  0.386
2022 Littau JL, Velilla L, Hase Y, Villalba-Moreno ND, Hagel C, Drexler D, Osorio Restrepo S, Villegas A, Lopera F, Vargas S, Glatzel M, Krasemann S, Quiroz YT, Arboleda-Velasquez JF, Kalaria R, et al. Evidence of beta amyloid independent small vessel disease in familial Alzheimer's disease. Brain Pathology (Zurich, Switzerland). e13097. PMID 35695802 DOI: 10.1111/bpa.13097  0.776
2022 Gomez LR, Albers MW, Baena A, Vila-Castelar C, Fox-Fuller JT, Sanchez J, Jain F, Albers AD, Lopera F, Quiroz YT. Olfactory Function and Markers of Brain Pathology in Non-Demented Individuals with Autosomal Dominant Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 35694921 DOI: 10.3233/JAD-220075  0.408
2022 Guzmán-Vélez E, Diez I, Schoemaker D, Pardilla-Delgado E, Vila-Castelar C, Fox-Fuller JT, Baena A, Sperling RA, Johnson KA, Lopera F, Sepulcre J, Quiroz YT. Amyloid-β and tau pathologies relate to distinctive brain dysconnectomics in preclinical autosomal-dominant Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 119: e2113641119. PMID 35380901 DOI: 10.1073/pnas.2113641119  0.394
2022 Jacobs HIL, Becker JA, Kwong K, Munera D, Ramirez-Gomez L, Engels-Domínguez N, Sanchez JS, Vila-Castelar C, Baena A, Sperling RA, Johnson KA, Lopera F, Quiroz YT. Waning locus coeruleus integrity precedes cortical tau accrual in preclinical autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35298083 DOI: 10.1002/alz.12656  0.402
2022 Levin J, Vöglein J, Quiroz YT, Bateman RJ, Ghisays V, Lopera F, McDade E, Reiman E, Tariot PN, Morris JC. Testing the amyloid cascade hypothesis: Prevention trials in autosomal dominant Alzheimer disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35212149 DOI: 10.1002/alz.12624  0.381
2022 Quiroz YT, Solis M, Aranda MP, Arbaje AI, Arroyo-Miranda M, Cabrera LY, Carrasquillo MM, Corrada MM, Crivelli L, Diminich ED, Dorsman KA, Gonzales M, González HM, Gonzalez-Seda AL, Grinberg LT, ... ... Lopera F, et al. Addressing the disparities in dementia risk, early detection and care in Latino populations: Highlights from the second Latinos & Alzheimer's Symposium. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35199931 DOI: 10.1002/alz.12589  0.343
2022 Vila-Castelar C, Tariot PN, Sink KM, Clayton D, Langbaum JB, Thomas RG, Chen Y, Su Y, Chen K, Hu N, Giraldo-Chica M, Tobón C, Acosta-Baena N, Luna E, Londoño M, ... ... Lopera F, et al. Sex differences in cognitive resilience in preclinical autosomal-dominant Alzheimer's disease carriers and non-carriers: Baseline findings from the API ADAD Colombia Trial. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35103388 DOI: 10.1002/alz.12552  0.408
2021 Ramos C, Villalba C, García J, Lanata S, López H, Aguillón D, Cordano C, Madrigal L, Aguirre-Acevedo DC, Lopera F. Substance Use-Related Cognitive Decline in Families with Autosomal Dominant Alzheimer's Disease: A Cohort Study. Journal of Alzheimer's Disease : Jad. PMID 34924385 DOI: 10.3233/JAD-215169  0.359
2021 Fox-Fuller JT, Torrico-Teave H, d'Oleire Uquillas F, Chen K, Su Y, Chen Y, Brickhouse M, Sanchez JS, Aguero C, Jacobs HIL, Hampton O, Guzmán-Vélez E, Vila-Castelar C, Aguirre-Acevedo DC, Baena A, ... ... Lopera F, et al. Cortical thickness across the lifespan in a Colombian cohort with autosomal-dominant Alzheimer's disease: A cross-sectional study. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12233. PMID 34541287 DOI: 10.1002/dad2.12233  0.38
2021 Ghisays V, Lopera F, Goradia DD, Protas HD, Malek-Ahmadi MH, Chen Y, Devadas V, Luo J, Lee W, Baena A, Bocanegra Y, Guzmán-Vélez E, Pardilla-Delgado E, Vila-Castelar C, Fox-Fuller JT, et al. PET evidence of preclinical cerebellar amyloid plaque deposition in autosomal dominant Alzheimer's disease-causing Presenilin-1 E280A mutation carriers. Neuroimage. Clinical. 31: 102749. PMID 34252876 DOI: 10.1016/j.nicl.2021.102749  0.427
2021 Baena A, Bocanegra Y, Torres V, Vila-Castelar C, Guzmán-Vélez E, Fox-Fuller JT, Gatchel JR, Sánchez J, Pluim CF, Ramirez-Gómez L, Martínez J, Pineda D, Lopera F, Quiroz YT. Neuroticism Is Associated with Tau Pathology in Cognitively Unimpaired Individuals with Autosomal Dominant Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 34219716 DOI: 10.3233/JAD-210185  0.418
2021 Martinez JE, Pardilla-Delgado E, Guzmán-Vélez E, Vila-Castelar C, Amariglio R, Gatchel J, Aguirre-Acevedo DC, Bocanegra Y, Baena A, Henao E, Tirado V, Muñoz C, Giraldo-Chica M, Lopera F, Quiroz YT. Subjective Cognitive Decline and its Relation to Verbal Memory and Sex in Cognitively Unimpaired Individuals from a Colombian Cohort with Autosomal-Dominant Alzheimer's Disease. Journal of the International Neuropsychological Society : Jins. 1-9. PMID 34187609 DOI: 10.1017/S1355617721000801  0.348
2021 Pardilla-Delgado E, Torrico-Teave H, Sanchez JS, Ramirez-Gomez LA, Baena A, Bocanegra Y, Vila-Castelar C, Fox-Fuller JT, Guzmán-Vélez E, Martínez J, Alvarez S, Ochoa-Escudero M, Lopera F, Quiroz YT. Associations between subregional thalamic volume and brain pathology in autosomal dominant Alzheimer's disease. Brain Communications. 3: fcab101. PMID 34095834 DOI: 10.1093/braincomms/fcab101  0.443
2021 Guzmán-Vélez E, Zetterberg H, Fox-Fuller JT, Vila-Castelar C, Sanchez JS, Baena A, Garcia-Ospina G, Aguillon D, Pardilla-Delgado E, Gatchel JR, Sperling RA, Johnson K, Reiman EM, Blennow K, Lopera F, et al. Associations between plasma neurofilament light, in vivo brain pathology, and cognition in non-demented individuals with autosomal-dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33527648 DOI: 10.1002/alz.12248  0.41
2021 Sanchez JS, Hanseeuw BJ, Lopera F, Sperling RA, Baena A, Bocanegra Y, Aguillon D, Guzmán-Vélez E, Pardilla-Delgado E, Ramirez-Gomez L, Vila-Castelar C, Martinez JE, Fox-Fuller JT, Ramos C, Ochoa-Escudero M, et al. Longitudinal amyloid and tau accumulation in autosomal dominant Alzheimer's disease: findings from the Colombia-Boston (COLBOS) biomarker study. Alzheimer's Research & Therapy. 13: 27. PMID 33451357 DOI: 10.1186/s13195-020-00765-5  0.392
2020 Sepulveda-Falla D, Chavez-Gutierrez L, Portelius E, Vélez JI, Dujardin S, Barrera-Ocampo A, Dinkel F, Hagel C, Puig B, Mastronardi C, Lopera F, Hyman BT, Blennow K, Arcos-Burgos M, de Strooper B, et al. A multifactorial model of pathology for age of onset heterogeneity in familial Alzheimer's disease. Acta Neuropathologica. PMID 33319314 DOI: 10.1007/s00401-020-02249-0  0.817
2020 Vannini P, Hanseeuw BJ, Gatchel JR, Sikkes SAM, Alzate D, Zuluaga Y, Moreno S, Mendez L, Baena A, Ospina-Lopera P, Tirado V, Henao E, Acosta-Baena N, Giraldo M, Lopera F, et al. Trajectory of Unawareness of Memory Decline in Individuals With Autosomal Dominant Alzheimer Disease. Jama Network Open. 3: e2027472. PMID 33263761 DOI: 10.1001/jamanetworkopen.2020.27472  0.366
2020 Llibre-Guerra JJ, Li Y, Allegri RF, Mendez PC, Surace EI, Llibre-Rodriguez JJ, Sosa AL, Aláez-Verson C, Longoria EM, Tellez A, Carrillo-Sánchez K, Flores-Lagunes LL, Sánchez V, Takada LT, Nitrini R, ... ... Lopera F, et al. Dominantly inherited Alzheimer's disease in Latin America: Genetic heterogeneity and clinical phenotypes. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33226734 DOI: 10.1002/alz.12227  0.373
2020 Armstrong GW, Kim LA, Vingopoulos F, Park JY, Garg I, Kasetty M, Silverman RF, Zeng R, Douglas VP, Lopera F, Baena A, Giraldo M, Norton D, Cronin-Golomb A, Arboleda-Velasquez JF, et al. Retinal Imaging Findings in Carriers With PSEN1-Associated Early-Onset Familial Alzheimer Disease Before Onset of Cognitive Symptoms. Jama Ophthalmology. PMID 33180114 DOI: 10.1001/jamaophthalmol.2020.4909  0.396
2020 Ramos C, Aguillon D, Cordano C, Lopera F. Genetics of dementia: insights from Latin America. Dementia & Neuropsychologia. 14: 223-236. PMID 32973976 DOI: 10.1590/1980-57642020dn14-030004  0.445
2020 Vila-Castelar C, Guzmán-Vélez E, Pardilla-Delgado E, Buckley R, Bocanegra Y, Baena A, Fox-Fuller JT, Tirado V, Munoz C, Giraldo M, Acosta-Baena N, Rios-Romenets S, Langbaum JB, Tariot PN, Lopera F, et al. Examining Sex Differences in Markers of Cognition and Neurodegeneration in Autosomal Dominant Alzheimer's Disease: Preliminary Findings from the Colombian Alzheimer's Prevention Initiative Biomarker Study. Journal of Alzheimer's Disease : Jad. PMID 32925067 DOI: 10.3233/Jad-200723  0.538
2020 Vila-Castelar C, Muñoz N, Papp KV, Amariglio RE, Baena A, Guzmán-Vélez E, Bocanegra Y, Sanchez JS, Reiman EM, Johnson KA, Sperling RA, Lopera F, Rentz DM, Quiroz YT. The Latin American Spanish version of the Face-Name Associative Memory Exam is sensitive to cognitive and pathological changes in preclinical autosomal dominant Alzheimer's disease. Alzheimer's Research & Therapy. 12: 104. PMID 32912283 DOI: 10.1186/s13195-020-00671-w  0.5
2020 Dinkel F, Trujillo-Rodriguez D, Villegas A, Streffer J, Mercken M, Lopera F, Glatzel M, Sepulveda-Falla D. Decreased Deposition of Beta-Amyloid 1-38 and Increased Deposition of Beta-Amyloid 1-42 in Brain Tissue of Presenilin-1 E280A Familial Alzheimer's Disease Patients. Frontiers in Aging Neuroscience. 12: 220. PMID 32848702 DOI: 10.3389/Fnagi.2020.00220  0.742
2020 Norton DJ, Parra MA, Sperling RA, Baena A, Guzman-Velez E, Jin DS, Andrea N, Khang J, Schultz A, Rentz DM, Pardilla-Delgado E, Fuller J, Johnson K, Reiman EM, Lopera F, et al. Visual short-term memory relates to tau and amyloid burdens in preclinical autosomal dominant Alzheimer's disease. Alzheimer's Research & Therapy. 12: 99. PMID 32825838 DOI: 10.1186/S13195-020-00660-Z  0.442
2020 Bocanegra Y, Fox-Fuller JT, Baena A, Guzmán-Vélez E, Vila-Castelar C, Martínez J, Torrico-Teave H, Lopera F, Quiroz YT. Association Between Visual Memory and Amyloid and Tau Pathology in Preclinical Autosomal Dominant Alzheimer's Disease. Journal of the International Neuropsychological Society : Jins. 1-9. PMID 32762790 DOI: 10.1017/S1355617720000673  0.5
2020 Palmqvist S, Janelidze S, Quiroz YT, Zetterberg H, Lopera F, Stomrud E, Su Y, Chen Y, Serrano GE, Leuzy A, Mattsson-Carlgren N, Strandberg O, Smith R, Villegas A, Sepulveda-Falla D, et al. Discriminative Accuracy of Plasma Phospho-tau217 for Alzheimer Disease vs Other Neurodegenerative Disorders. Jama. PMID 32722745 DOI: 10.1001/Jama.2020.12134  0.737
2020 Kivipelto M, Mangialasche F, Snyder HM, Allegri R, Andrieu S, Arai H, Baker L, Belleville S, Brodaty H, Brucki SM, Calandri I, Caramelli P, Chen C, Chertkow H, Chew E, ... ... Lopera F, et al. World-Wide FINGERS Network: A global approach to risk reduction and prevention of dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32627328 DOI: 10.1002/Alz.12123  0.351
2020 Guzmán-Vélez E, Martínez J, Papp K, Baena A, Vila-Castelar C, Artola A, Schultz AP, Bocanegra Y, Sanchez J, Rentz D, Tariot PN, Reiman EM, Sperling R, Johnson KA, Lopera F, et al. Associative memory and in vivo brain pathology in asymptomatic presenilin-1 E280A carriers. Neurology. PMID 32611637 DOI: 10.1212/Wnl.0000000000010177  0.395
2020 Schoemaker D, Zuluaga Y, Viswanathan A, Shrimer M, Torrico-Teave H, Velilla L, Ospina C, Ospina GG, Lopera F, Arboleda-Velasquez JF, Quiroz YT. The INECO Frontal Screening for the Evaluation of Executive Dysfunction in Cerebral Small Vessel Disease: Evidence from Quantitative MRI in a CADASIL Cohort from Colombia. Journal of the International Neuropsychological Society : Jins. 1-13. PMID 32487276 DOI: 10.1017/S1355617720000533  0.338
2020 Quiroz YT, Zetterberg H, Reiman EM, Chen Y, Su Y, Fox-Fuller JT, Garcia G, Villegas A, Sepulveda-Falla D, Villada M, Arboleda-Velasquez JF, Guzmán-Vélez E, Vila-Castelar C, Gordon BA, Schultz SA, ... ... Lopera F, et al. Plasma neurofilament light chain in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional and longitudinal cohort study. The Lancet. Neurology. 19: 513-521. PMID 32470423 DOI: 10.1016/S1474-4422(20)30137-X  0.705
2020 Soto-Mercado V, Mendivil-Perez M, Velez-Pardo C, Lopera F, Jimenez-Del-Rio M. Cholinergic-like neurons carrying PSEN1 E280A mutation from familial Alzheimer's disease reveal intraneuronal sAPPβ fragments accumulation, hyperphosphorylation of TAU, oxidative stress, apoptosis and Ca2+ dysregulation: Therapeutic implications. Plos One. 15: e0221669. PMID 32437347 DOI: 10.1371/Journal.Pone.0221669  0.47
2020 Rios-Romenets S, Lopera F, Sink KM, Hu N, Lian Q, Guthrie H, Smith J, Cho W, Mackey H, Langbaum JB, Thomas RG, Giraldo-Chica M, Tobon C, Acosta-Baena N, Muñoz C, et al. Baseline demographic, clinical, and cognitive characteristics of the Alzheimer's Prevention Initiative (API) Autosomal-Dominant Alzheimer's Disease Colombia Trial. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32418361 DOI: 10.1002/Alz.12109  0.425
2020 Borda MG, Lopera F, Buritica O, Cerquera-Cleves C, Gonzalez MC, Garcia-Cifuentes E, Jaramillo-Jimenez A, Aguillon D, Bocanegra Y, Munoz-Ospina BE, Cano-Gutierrez CA, Patiño-Hernandez D, Tobón C, Santamaría-García H, Santacruz JM, et al. Colombian consortium for the study of Lewy body dementia COL-DLB. Journal of the Neurological Sciences. 412: 116807. PMID 32247904 DOI: 10.1016/J.Jns.2020.116807  0.33
2020 Pardilla-Delgado E, Gomez LR, Baena AY, Montes MI, Bocanegra Y, Martinez JE, Lopera F, Quiroz YT. 0421 Decreased Actigraphic Daytime Activity is Associated with Lower Memory Performance in Cognitively-Unimpaired Individuals with Autosomal Dominant Alzheimer’s Disease Sleep. 43. DOI: 10.1093/Sleep/Zsaa056.418  0.356
2019 Gatchel JR, Lopera F, Norton DJ, Baena A, Guzman-Velez E, Sanchez JS, d'Oleire Uquillas F, Schultz A, Vannini P, Artola A, Amariglio RE, Rentz DM, Tariot PN, Reiman EM, Johnson KA, et al. Association of subjective cognitive decline with markers of brain pathology in preclinical autosomal dominant Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 31874859 DOI: 10.1136/Jnnp-2019-321205  0.448
2019 Vila-Castelar C, Papp KV, Amariglio RE, Torres VL, Baena A, Gomez D, Rendon J, Samaroo A, Lopera F, Rentz DM, Quiroz YT. Validation of the Latin American Spanish version of the face-name associative memory exam in a Colombian Sample. The Clinical Neuropsychologist. 1-12. PMID 31851865 DOI: 10.1080/13854046.2019.1690050  0.301
2019 Villalba AC, García J, Ramos C, Cuastumal AR, Aguillón D, Aguirre-Acevedo DC, Madrigal L, Lopera F. Mental Disorders in Young Adults from Families with the Presenilin-1 Gene Mutation E280A in the Preclinical Stage of Alzheimer's Disease. Journal of Alzheimer's Disease Reports. 3: 241-250. PMID 31754656 DOI: 10.3233/ADR-190139  0.389
2019 Arboleda-Velasquez JF, Lopera F, O'Hare M, Delgado-Tirado S, Marino C, Chmielewska N, Saez-Torres KL, Amarnani D, Schultz AP, Sperling RA, Leyton-Cifuentes D, Chen K, Baena A, Aguillon D, Rios-Romenets S, et al. Resistance to autosomal dominant Alzheimer's disease in an APOE3 Christchurch homozygote: a case report. Nature Medicine. PMID 31686034 DOI: 10.1038/S41591-019-0611-3  0.546
2019 Vélez JI, Lopera F, Silva CT, Villegas A, Espinosa LG, Vidal OM, Mastronardi CA, Arcos-Burgos M. Familial Alzheimer's Disease and Recessive Modifiers. Molecular Neurobiology. PMID 31664702 DOI: 10.1007/S12035-019-01798-0  0.501
2019 Villalba AC, García J, Ramos C, Cuastumal AR, Aguillón D, Aguirre-Acevedo DC, Madrigal L, Lopera F. Mental Disorders in Young Adults from Families with the Presenilin-1 Gene Mutation E280A in the Preclinical Stage of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 31381509 DOI: 10.3233/Jad-181013  0.489
2019 Torres VL, Vila-Castelar C, Bocanegra Y, Baena A, Guzmán-Vélez E, Aguirre-Acevedo DC, Tirado V, Munoz C, Henao E, Moreno S, Giraldo M, Acosta N, Rios Romenets S, Langbaum JB, Cho W, ... ... Lopera F, et al. Normative data stratified by age and education for a Spanish neuropsychological test battery: Results from the Colombian Alzheimer's prevention initiative registry. Applied Neuropsychology. Adult. 1-15. PMID 31230490 DOI: 10.1080/23279095.2019.1627357  0.378
2019 Arcos-Burgos M, Lopera F, Sepulveda-Falla D, Mastronardi C. Neural Plasticity during Aging. Neural Plasticity. 2019: 6042132. PMID 31049053 DOI: 10.1155/2019/6042132  0.625
2019 Rios-Urrego CD, Vásquez-Correa JC, Vargas-Bonilla JF, Nöth E, Lopera F, Orozco-Arroyave JR. Analysis and evaluation of handwriting in patients with Parkinson's disease using kinematic, geometrical, and non-linear features. Computer Methods and Programs in Biomedicine. 173: 43-52. PMID 31046995 DOI: 10.1016/J.Cmpb.2019.03.005  0.356
2019 Vallejo-Diez S, Fleischer A, Martín-Fernández JM, Sánchez-Gilabert A, Castresana M, Aguillón D, Villegas A, Mastronardi CA, Espinosa LG, Arcos-Burgos M, Del Pozo Á, Herrán E, Gainza E, Isaza-Ruget M, Lopera F, et al. Generation of one iPSC line (IMEDEAi006-A) from an early-onset familial Alzheimer's Disease (fAD) patient carrying the E280A mutation in the PSEN1 gene. Stem Cell Research. 37: 101440. PMID 31026686 DOI: 10.1016/J.Scr.2019.101440  0.448
2019 Mendivil-Perez M, Velez-Pardo C, Kosik KS, Lopera F, Jimenez-Del-Rio M. iPSCs-derived nerve-like cells from familial Alzheimer's disease PSEN 1 E280A reveal increased amyloid-beta levels and loss of the Y chromosome. Neuroscience Letters. PMID 30904577 DOI: 10.1016/J.Neulet.2019.03.032  0.462
2019 Ramirez Aguilar L, Acosta-Uribe J, Giraldo MM, Moreno S, Baena A, Alzate D, Cuastumal R, Aguillón D, Madrigal L, Saldarriaga A, Navarro A, Garcia GP, Aguirre-Acevedo DC, Geier EG, Cochran JN, ... ... Lopera F, et al. Genetic origin of a large family with a novel PSEN1 mutation (Ile416Thr). Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30745123 DOI: 10.1016/J.Jalz.2018.12.010  0.455
2019 Hanseeuw BJ, Lopera F, Sperling RA, Norton DJ, Guzman-Velez E, Baena A, Pardilla-Delgado E, Schultz AP, Gatchel J, Jin D, Chen K, Reiman EM, Johnson KA, Quiroz YT. Striatal amyloid is associated with tauopathy and memory decline in familial Alzheimer's disease. Alzheimer's Research & Therapy. 11: 17. PMID 30717814 DOI: 10.1186/S13195-019-0468-1  0.467
2019 Sepulveda-Falla D, Villegas A, Lopera F, Glatzel M. The Colombian-German network for neurodegenerative research: UndoAD. The Lancet. Neurology. 18: 29. PMID 30563680 DOI: 10.1016/S1474-4422(18)30458-7  0.68
2019 Bocanegra Y, Baena A, Carmona J, Aguirre DC, Pineda D, Buriticá O, Quiroz Y, Lopera F. Neuropsychiatric Symptoms in Parkinson’s Disease with and without Mild Cognitive Impairment Archives of Clinical Neuropsychology. 34: 1238-1238. DOI: 10.1093/Arclin/Acz029.05  0.338
2019 Bocanegra Y, Guzman-Velez E, Baena A, Vila-Castelar C, Artola A, Gatchel JR, Pardilla-Delgado E, Fuller J, Sperling RA, Johnson KA, Lopera F, Quiroz YT. P4-608: Tau Accumulation And Visual Memory In Cognitively Unimpaired Psen1 E280A Mutation Carriers Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.08.156  0.358
2019 Guzman-Velez E, Martínez J, Papp KV, Baena A, Schultz AP, Bocanegra Y, Sanchez JS, Rentz DM, Reiman EM, Sperling RA, Johnson KA, Lopera F, Quiroz YT. P4-607: Free And Cued Memory Is Distinctly Related To Pathology In Preclinical Autosomal-Dominant Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.08.155  0.389
2019 Vila-Castelar C, Lopera F, Baena A, Tirado V, Muñoz C, Acosta-Baena N, Giraldo M, Rios-Romenets S, Guzman-Velez E, Pardilla-Delgado E, Tariot PN, Reiman EM, Quiroz YT. P1-378: Sex-Specific Associations Between Markers Of Alzheimer'S Disease Pathology, Neurodegeneration And Cognition In Autosomal Dominant Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.933  0.493
2019 Quiroz YT, Zetterberg H, Reiman EM, Chen Y, Garcia G, L AV, Sepulveda D, Villada M, Arboleda-Velasquez JF, Giraldo M, Guzman-Velez E, Vila-Castelar C, Pardilla-Delgado E, Fuller J, Protas H, ... ... Lopera F, et al. Plasma Neurofilament Light Measurements In More Than 2,100 Presenilin-1 E280A Mutation Carriers And Non-Carriers From The World’S Largest Autosomal Dominant Alzheimer’S Disease Kindred Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4861  0.357
2019 Quiroz YT, Tariot PN, Sink K, Clayton D, Langbaum JB, Thomas RG, Giraldo M, Tobon C, Acosta-Baena N, Luna E, Londono M, Ospina P, Tirado V, Alvarez S, Chen K, ... ... Lopera F, et al. F4-04-04: Association Between Cerebral Amyloidosis And Worse Cognitive Performance In Preclinical Autosomal Dominant Alzheimer'S Disease: Baseline Findings From The Api Colombia Autosomal Dominant Ad Trial Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4728  0.472
2019 Su Y, Rios-Romenets S, Tariot PN, Sink K, Clayton D, Hu N, Guthrie H, Smith J, Cho W, Langbaum JB, Thomas RG, Giraldo M, Tobon C, Acosta-Baena N, Navarro A, ... ... Lopera F, et al. F4-04-03: Relationships Between Baseline Brain Imaging Biomarker Measurements And Age In The Api Autosomal Dominant Alzheimer'S Disease Colombia Trial Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4727  0.391
2019 Acosta-Baena N, Rios-Romenets S, Muñoz C, Bocanegra Y, Henao E, Giraldo M, Tobon C, Sink K, Hu N, Guthrie H, Smith J, Cho W, Langbaum JB, Thomas RG, Chen K, ... ... Lopera F, et al. F4-04-02: Age-Related Changes In Baseline Cognitive Measures In Unimpaired Psen1 E280A Mutation Carriers And Non-Carriers In The Api Autosomal Dominant Alzheimer'S Disease Colombia Trial Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4726  0.439
2019 Tariot PN, Lopera F, Sink K, Hu N, Guthrie H, Smith J, Cho W, Langbaum JB, Thomas RG, Giraldo M, Tobon C, Acosta-Baena N, Munoz C, Ospina P, Torado V, et al. F4-04-01: Trial Design, Data Sharing Risk Mitigation, And Baseline Clinical And Cognitive Data From The Api Autosomal Dominant Alzheimer'S Disease Colombia Trial Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4725  0.352
2019 Sanchez JS, Lopera F, Sperling RA, Becker A, Artola A, Baena A, Jacobs HI, Hanseeuw BJ, Schultz AP, Gatchel JR, Katz S, Mayblyum D, Moody K, Price JC, Bocanegra Y, et al. P4-312: LONGITUDINAL PET MEASURES OF TAU AND AMYLOID ACCUMULATION IN AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE: FINDINGS FROM THE COLBOS PROJECT Alzheimer's & Dementia. 15: P1411-P1411. DOI: 10.1016/J.Jalz.2019.06.3982  0.447
2019 Jacobs HI, Becker A, Sperling RA, Guzman-Velez E, Baena A, Uquillas Fd, Artola A, Pardilla-Delgado E, Gatchel JR, Reiman EM, Johnson KA, Lopera F, Quiroz YT. P2-425: LOCUS COERULEUS INTENSITY IS ASSOCIATED WITH EARLY AMYLOID AND TAU PATHOLOGY IN PRECLINICAL AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P774-P775. DOI: 10.1016/J.Jalz.2019.06.2832  0.5
2019 Protas H, Pardilla-Delgado E, Lopera F, Johnson KA, Sperling RA, Artola A, Baena A, Bocanegra Y, Gatchel JR, Guzman-Velez E, Fuller J, Goradia DD, Thiyyagura P, VanGilder PS, Luo J, et al. Ic-P-058: Covarying Spatial Patterns Of Tau Deposition And Gray Matter Atrophy Unearthed By The Informed Multimodal Partial Least Squares (Mmpls) In Autosomal Dominant Alzheimer'S Disease: Findings From The Colbos Project Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2767  0.387
2018 Zuluaga-Castaño Y, Montoya-Arenas DA, Velilla L, Ospina C, Arboleda-Velasquez JF, Quiroz YT, Lopera F. Cognitive performance in asymptomatic carriers of mutations R1031C and R141C in CADASIL. International Journal of Psychological Research. 11: 46-55. PMID 32612778 DOI: 10.21500/20112084.3373  0.366
2018 Rendon J, Zuluaga Y, Velilla L, Ochoa J, Arboleda-Velasquez JF, Budson A, Lopera F, Quiroz YT. Event-Related Potential Correlates of Recognition Memory in Asymptomatic Individuals with CADASIL. Brain Research. PMID 30445028 DOI: 10.1016/J.Brainres.2018.11.016  0.385
2018 García-Toro M, Sánchez-Gómez MC, Madrigal Zapata L, Lopera FJ. "In the flesh": Narratives of family caregivers at risk of Early-onset Familial Alzheimer's Disease. Dementia (London, England). 1471301218801501. PMID 30253659 DOI: 10.1177/1471301218801501  0.311
2018 Vélez JI, Lopera F, Creagh PK, Piñeros LB, Das D, Cervantes-Henríquez ML, Acosta-López JE, Isaza-Ruget MA, Espinosa LG, Easteal S, Quintero GA, Silva CT, Mastronardi CA, Arcos-Burgos M. Targeting Neuroplasticity, Cardiovascular, and Cognitive-Associated Genomic Variants in Familial Alzheimer's Disease. Molecular Neurobiology. PMID 30112632 DOI: 10.1007/S12035-018-1298-Z  0.451
2018 Rios-Romenets S, Acosta-Baena N, Lopez L, Madrigal-Zapata L, Street H, Jakimovich L, Langbaum JB, Cho W, Reiman EM, Tariot PN, Lopera F. Adherence/Retention Alzheimer's Prevention Initiative Colombia Plan. Alzheimer's & Dementia (New York, N. Y.). 4: 283-287. PMID 30090848 DOI: 10.1016/J.Trci.2018.06.010  0.364
2018 Guzmán-Vélez E, Jaimes S, Aguirre-Acevedo DC, Norton DJ, Papp KV, Amariglio R, Rentz D, Baena A, Henao E, Tirado V, Muñoz C, Giraldo M, Sperling RA, Lopera F, Quiroz YT. A Three-Factor Structure of Cognitive Functioning Among Carriers and Non-Carriers of Autosomal-Dominant Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 30040714 DOI: 10.1093/Arclin/Acw043.34  0.45
2018 Tariot PN, Lopera F, Langbaum JB, Thomas RG, Hendrix S, Schneider LS, Rios-Romenets S, Giraldo M, Acosta N, Tobon C, Ramos C, Espinosa A, Cho W, Ward M, Clayton D, et al. The Alzheimer's Prevention Initiative Autosomal-Dominant Alzheimer's Disease Trial: A study of crenezumab versus placebo in preclinical E280A mutation carriers to evaluate efficacy and safety in the treatment of autosomal-dominant Alzheimer's disease, including a placebo-treated noncarrier cohort. Alzheimer's & Dementia (New York, N. Y.). 4: 150-160. PMID 29955659 DOI: 10.1016/J.Trci.2018.02.002  0.523
2018 Quiroz YT, Sperling RA, Norton DJ, Baena A, Arboleda-Velasquez JF, Cosio D, Schultz A, Lapoint M, Guzman-Velez E, Miller JB, Kim LA, Chen K, Tariot PN, Lopera F, Reiman EM, et al. Association Between Amyloid and Tau Accumulation in Young Adults With Autosomal Dominant Alzheimer Disease. Jama Neurology. PMID 29435558 DOI: 10.1001/Jamaneurol.2017.4907  0.508
2018 Reiman EM, Sink KM, Hu N, Guthrie H, Smith J, Cho W, Knoll KL, Langbaum JB, Thomas RG, Toga AW, Chen K, Boker CA, Alvarez S, Quiroz YT, Romenets SR, ... Lopera F, et al. P4‐209: A Public Resource Of Baseline Data From The Api Autosomal Dominant Alzheimer'S Disease Colombia Trial Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.07.030  0.41
2018 Ghisays V, Protas H, Chen Y, DeMarco EL, Tariot PN, Langbaum JB, Quiroz YT, Lopera F, Reiman EM, Chen K. COMPARING CEREBRAL WHITE MATTER, CEREBELLAR, AND PONTINE REFERENCE REGIONS TO CHARACTERIZE FLORBETAPIR PET MEASUREMENTS OF AMYLOID-β BURDEN IN PSEN1 E280A MUTATION CARRIERS AND NONCARRIERS FROM THE COLOMBIAN AUTOSOMAL DOMINANT ALZHEIMER’S DISEASE KINDRED Alzheimers & Dementia. 14: 20. DOI: 10.1016/J.Jalz.2018.06.2074  0.388
2017 Villamil-Ortiz JG, Barrera-Ocampo A, Arias-Londoño JD, Villegas A, Lopera F, Cardona-Gómez GP. Differential Pattern of Phospholipid Profile in the Temporal Cortex from E280A-Familiar and Sporadic Alzheimer's Disease Brains. Journal of Alzheimer's Disease : Jad. PMID 29125487 DOI: 10.3233/Jad-170554  0.781
2017 Norton DJ, Amariglio R, Protas H, Chen K, Aguirre-Acevedo DC, Pulsifer B, Castrillon G, Tirado V, Munoz C, Tariot P, Langbaum JB, Reiman EM, Lopera F, Sperling RA, Quiroz YT. Subjective memory complaints in preclinical autosomal dominant Alzheimer disease. Neurology. PMID 28878053 DOI: 10.1212/Wnl.0000000000004533  0.386
2017 Cornejo-Olivas M, Torres L, Velit-Salazar MR, Inca-Martinez M, Mazzetti P, Cosentino C, Micheli F, Perandones C, Dieguez E, Raggio V, Tumas V, Borges V, Ferraz HB, Rieder CRM, Shumacher-Schuh A, ... ... Lopera F, et al. Variable frequency of LRRK2 variants in the Latin American research consortium on the genetics of Parkinson's disease (LARGE-PD), a case of ancestry. Npj Parkinson's Disease. 3: 19. PMID 28649619 DOI: 10.1038/S41531-017-0020-6  0.361
2017 Parra MA, Mikulan E, Trujillo N, Sala SD, Lopera F, Manes F, Starr J, Ibanez A. Brain information sharing during visual short-term memory binding yields a memory biomarker for familial Alzheimer's disease. Current Alzheimer Research. PMID 28641509 DOI: 10.2174/1567205014666170614163316  0.41
2017 Ochoa JF, Alonso JF, Duque JE, Tobón CA, Baena A, Lopera F, Mañanas MA, Hernández AM. Precuneus Failures in Subjects of the PSEN1 E280A Family at Risk of Developing Alzheimer's Disease Detected Using Quantitative Electroencephalography. Journal of Alzheimer's Disease : Jad. PMID 28550254 DOI: 10.3233/Jad-161291  0.503
2017 Moreno DJ, Pino S, Ríos Á, Lopera F, Ostos H, Via M, Bedoya G. Genetic Ancestry and Susceptibility to Late-Onset Alzheimer's Disease (LOAD) in the Admixed Colombian Population. Alzheimer Disease and Associated Disorders. PMID 28369008 DOI: 10.1097/Wad.0000000000000195  0.487
2017 Quiroz YT, Pulsifer M, Chen K, Ramirez D, Londono N, Arboleda-Velasquez J, Martinez J, Chen Y, Guzman-Velez E, Norton D, Langbaum JB, Tariot P, Reiman EM, Lopera F. Cognitive Vulnerabilities In Presenilin-1 E280A Mutation-Carrying Children From The World’S Largest Autosomal-Dominant Alzheimer’S Disease Kindred Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.07.108  0.379
2017 Gatchel JR, Norton DJ, Baena A, Guzman-Velez E, Lopera F, Johnson K, Sperling RA, Marshall GA, Quiroz YT. [P4-243]: ANXIETY, SUBJECTIVE COGNITIVE DECLINE, AND CORTICAL AMYLOID IN PRECLINICAL AUTOSOMAL DOMINANT ALZHEIMER's DISEASE: A PRELIMINARY REPORT Alzheimer's & Dementia. 13: P1369-P1370. DOI: 10.1016/J.Jalz.2017.06.2111  0.452
2017 Guzman-Velez E, Castrillon G, Chen K, Norton D, Baena A, Acosta-Uribe J, Cuastumal A, Lopera F, Sperling RA, Reiman EM, Johnson K, Quiroz YT. [P1-030]: RELATIONSHIPS BETWEEN MEMORY FUNCTION, TAU PATHOLOGY AND FUNCTIONAL CONNECTIVITY IN THE DEFAULT MODE NETWORK IN AUTOSOMAL-DOMINANT ALZHEIMER's DISEASE: A PRELIMINARY REPORT Alzheimer's & Dementia. 13: P245-P245. DOI: 10.1016/J.Jalz.2017.06.097  0.398
2016 Barrera-Ocampo A, Lopera F. Amyloid-beta immunotherapy: the hope for Alzheimer disease? Colombia Medica (Cali, Colombia). 47: 203-212. PMID 28293044 DOI: 10.25100/Cm.V47I4.2640  0.797
2016 Moreno DJ, Ruiz S, Ríos Á, Lopera F, Ostos H, Via M, Bedoya G. Association of GWAS Top Genes With Late-Onset Alzheimer's Disease in Colombian Population. American Journal of Alzheimer's Disease and Other Dementias. 1533317516679303. PMID 28084078 DOI: 10.1177/1533317516679303  0.39
2016 Cardona-Gómez GP, Lopera F. Dementia, Preclinical Studies in Neurodegeneration and its Potential for Translational Medicine in South America. Frontiers in Aging Neuroscience. 8: 304. PMID 28066230 DOI: 10.3389/Fnagi.2016.00304  0.441
2016 Ochoa JF, Alonso JF, Duque JE, Tobón CA, Mañanas MA, Lopera F, Hernández AM. Successful Scene Encoding Induces Increased Directed Connectivity in Presymptomatic Early-Onset Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 27792014 DOI: 10.3233/Jad-160803  0.48
2016 Vélez JI, Lopera F, Patel HR, Johar AS, Cai Y, Rivera D, Tobón C, Villegas A, Sepulveda-Falla D, Lehmann SG, Easteal S, Mastronardi CA, Arcos-Burgos M. Mutations modifying sporadic Alzheimer's disease age of onset. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. PMID 27573710 DOI: 10.1002/Ajmg.B.32493  0.76
2016 Pietto M, Parra MA, Trujillo N, Flores F, García AM, Bustin J, Richly P, Manes F, Lopera F, Ibáñez A, Baez S. Behavioral and Electrophysiological Correlates of Memory Binding Deficits in Patients at Different Risk Levels for Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 27372640 DOI: 10.3233/Jad-160056  0.427
2016 Uribe-Arias A, Posada-Duque RA, González-Billault C, Villegas A, Lopera F, Cardona-Gómez GP. p120-catenin is necessary for neuroprotection induced by CDK5 silencing in models of Alzheimer's disease. Journal of Neurochemistry. PMID 27273428 DOI: 10.1111/Jnc.13697  0.368
2016 Primo V, Graham M, Bigger-Allen AA, Chick JM, Ospina C, Quiroz YT, Manent J, Gygi SP, Lopera F, D'Amore PA, Arboleda-Velasquez JF. Blood Biomarkers in a Mouse Model of CADASIL. Brain Research. PMID 27174004 DOI: 10.1016/J.Brainres.2016.05.008  0.31
2016 Vélez JI, Rivera D, Mastronardi CA, Patel HR, Tobón C, Villegas A, Cai Y, Easteal S, Lopera F, Arcos-Burgos M. A Mutation in DAOA Modifies the Age of Onset in PSEN1 E280A Alzheimer's Disease. Neural Plasticity. 2016: 9760314. PMID 26949549 DOI: 10.1155/2016/9760314  0.439
2016 Aguirre-Acevedo DC, Lopera F, Henao E, Tirado V, Muñoz C, Giraldo M, Bangdiwala SI, Reiman EM, Tariot PN, Langbaum JB, Quiroz YT, Jaimes F. Cognitive Decline in a Colombian Kindred With Autosomal Dominant Alzheimer Disease: A Retrospective Cohort Study. Jama Neurology. PMID 26902171 DOI: 10.1001/Jamaneurol.2015.4851  0.405
2016 Vélez JI, Rivera D, Mastronardi CA, Patel HR, Tobón C, Villegas A, Cai Y, Easteal S, Lopera F, Arcos-Burgos M. A Mutation in DAOA Modifies the Age of Onset in PSEN1 E280A Alzheimer's Disease Neural Plasticity. 2016. DOI: 10.1155/2016/9760314  0.396
2016 Langbaum J, Tariot P, Reiman E, Cho W, Paul R, Ward M, Romenets SR, Lopera F. The Alzheimer’s Prevention Initiative (API) Autosomal Dominant Alzheimer’s Disease (ADAD) trial Neurobiology of Aging. 39. DOI: 10.1016/J.Neurobiolaging.2016.01.046  0.347
2016 Rios-Romenets S, Lopez H, Lopez L, Hincapie L, Saldarriaga A, Madrigal L, Piedrahita F, Navarro A, Acosta-Uribe J, Ramirez L, Giraldo M, Acosta-Baena N, Sánchez S, Ramos C, Muñoz C, ... ... Lopera F, et al. The Colombian Alzheimer's Prevention Initiative (API) Registry Alzheimers & Dementia. 13: 602-605. DOI: 10.1016/J.Jalz.2016.09.010  0.47
2016 Weninger S, Reiman EM, Langbaum JB, Tariot PN, Lopera F, Bateman R, Morris JC, Sperling RA, Aisen PS, Roses AD, Welsh-Bohmer KA, Carrillo M. F4-03-01: Collaboration for Alzheimer's Prevention (CAP): Advancing the Evaluation of Preclinical Alzheimer's Disease Treatments Alzheimer's & Dementia. 12: P325-P326. DOI: 10.1016/J.Jalz.2016.06.596  0.431
2016 Quiroz YT, Sperling RA, Baena A, Arboleda-Velasquez J, Schultz AP, Cosio DM, LaPoint MR, Judge K, Jaimes SY, Norton DJ, Reiman EM, Lopera F, Johnson K. IC-P-198: TAU and Amyloid PET Imaging in a Colombian Kindred with Autosomal-Dominant Alzheimer's Disease Alzheimer's & Dementia. 12: P143-P144. DOI: 10.1016/J.Jalz.2016.06.229  0.426
2016 Parra MA, Della Sala S, Lopera F, Orrego NT, Manes F, Starr JM, Cecchi M, Ibañez A. P1-372: Towards a Novel Memory Biomarker for Alzheimer’s Disease Relying on Eeg-Based Mobile Brain Imaging Technologies Alzheimer's & Dementia. 12: P574-P574. DOI: 10.1016/J.Jalz.2016.06.1124  0.306
2016 Norton DJ, Baena A, Pulsifier B, Lopera F, Quiroz YT. P1-279: Face-Name Recognition Memory in Preclinical Autosomal-Dominant Alzheimer’s Disease: An FMRI Study Alzheimer's & Dementia. 12: P525-P525. DOI: 10.1016/J.Jalz.2016.06.1029  0.308
2016 Quiroz YT, Tobon C, Muñoz C, Deason R, McKeever J, Velilla L, Arboleda-Velasquez J, Lopera F, Budson A. Neural Correlates of Recognition Memory in Preclinical Young-Onset Dementia International Journal of Psychophysiology. 108: 51. DOI: 10.1016/J.Ijpsycho.2016.07.170  0.314
2015 Giraldo-Chica M, Acosta-Baena N, Urbano L, Velilla L, Lopera F, Pineda N. Novel cerebrotendinous xanthomatosis mutation causes familial early dementia in Colombia. BioméDica : Revista Del Instituto Nacional De Salud. 35: 563-71. PMID 26844446 DOI: 10.7705/Biomedica.V35I4.2690  0.414
2015 Vélez JI, Lopera F, Sepulveda-Falla D, Patel HR, Johar AS, Chuah A, Tobón C, Rivera D, Villegas A, Cai Y, Peng K, Arkell R, Castellanos FX, Andrews SJ, Silva Lara MF, et al. APOE*E2 allele delays age of onset in PSEN1 E280A Alzheimer's disease. Molecular Psychiatry. PMID 26619808 DOI: 10.1038/Mp.2015.177  0.729
2015 Aguirre-Acevedo DC, Jaimes-Barragán F, Henao E, Tirado V, Muñoz C, Reiman EM, Tariot PN, Langbaum JB, Lopera F. Diagnostic accuracy of CERAD total score in a Colombian cohort with mild cognitive impairment and Alzheimer's disease affected by E280A mutation on presenilin-1 gene. International Psychogeriatrics / Ipa. 1-8. PMID 26478578 DOI: 10.1017/S1041610215001660  0.504
2015 Reiman EM, Langbaum JB, Tariot PN, Lopera F, Bateman RJ, Morris JC, Sperling RA, Aisen PS, Roses AD, Welsh-Bohmer KA, Carrillo MC, Weninger S. CAP-advancing the evaluation of preclinical Alzheimer disease treatments. Nature Reviews. Neurology. PMID 26416539 DOI: 10.1038/Nrneurol.2015.177  0.442
2015 Quiroz YT, Willment KC, Castrillon G, Muniz M, Lopera F, Budson A, Stern CE. Successful Scene Encoding in Presymptomatic Early-Onset Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. 47: 955-64. PMID 26401774 DOI: 10.3233/Jad-150214  0.513
2015 Lalli MA, Bettcher BM, Arcila ML, Garcia G, Guzman C, Madrigal L, Ramirez L, Acosta-Uribe J, Baena A, Wojta KJ, Coppola G, Fitch R, de Both MD, Huentelman MJ, Reiman EM, ... ... Lopera F, et al. Whole-genome sequencing suggests a chemokine gene cluster that modifies age at onset in familial Alzheimer's disease. Molecular Psychiatry. PMID 26324103 DOI: 10.1038/Mp.2015.131  0.459
2015 Langbaum JB, Hendrix S, Ayutyanont N, Bennett DA, Shah RC, Barnes LL, Lopera F, Reiman EM, Tariot PN. Establishing Composite Cognitive Endpoints for Use in Preclinical Alzheimer's Disease Trials. The Journal of Prevention of Alzheimer's Disease. 2: 2-3. PMID 26273569 DOI: 10.14283/jpad.2015.46  0.301
2015 Quiroz YT, Schultz AP, Chen K, Protas HD, Brickhouse M, Fleisher AS, Langbaum JB, Thiyyagura P, Fagan AM, Shah AR, Muniz M, Arboleda-Velasquez JF, Munoz C, Garcia G, Acosta-Baena N, ... ... Lopera F, et al. Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease: A Cross-Sectional Study. Jama Neurology. PMID 26121081 DOI: 10.1001/Jamaneurol.2015.1099  0.364
2015 Parra MA, Saarimäki H, Bastin ME, Londoño AC, Pettit L, Lopera F, Della Sala S, Abrahams S. Memory binding and white matter integrity in familial Alzheimer's disease. Brain : a Journal of Neurology. 138: 1355-69. PMID 25762465 DOI: 10.1093/Brain/Awv048  0.374
2015 Fleisher AS, Chen K, Quiroz YT, Jakimovich LJ, Gutierrez Gomez M, Langois CM, Langbaum JB, Roontiva A, Thiyyagura P, Lee W, Ayutyanont N, Lopez L, Moreno S, Muñoz C, Tirado V, ... ... Lopera F, et al. Associations between biomarkers and age in the presenilin 1 E280A autosomal dominant Alzheimer disease kindred: a cross-sectional study. Jama Neurology. 72: 316-24. PMID 25580592 DOI: 10.1001/Jamaneurol.2014.3314  0.501
2015 Kosik KS, Muñoz C, Lopez L, Arcila ML, García G, Madrigal L, Moreno S, Ríos Romenets S, Lopez H, Gutierrez M, Langbaum JB, Cho W, Suliman S, Tariot PN, Ho C, ... ... Lopera F, et al. Homozygosity of the autosomal dominant Alzheimer disease presenilin 1 E280A mutation. Neurology. 84: 206-8. PMID 25471389 DOI: 10.1212/Wnl.0000000000001130  0.438
2015 MacPherson SE, Parra MA, Moreno S, Lopera F, Della Sala S. Dual memory task impairment in E280A presenilin-1 mutation carriers. Journal of Alzheimer's Disease : Jad. 44: 481-92. PMID 25352452 DOI: 10.3233/Jad-140990  0.389
2015 Quiroz YT, Protas H, Chen K, Roontiva A, Thiyyagura P, Fagan AM, Shah A, Gutierrez M, Londono M, Giraldo M, Munoz C, Tirado V, Velilla L, Garcia G, Jaimes SY, ... ... Lopera F, et al. Relationships between baseline biomarkers and subsequent cognitive decline in cognitively unimpaired PSEN1 E280A mutation carriers from the colombian kindred with autosomal dominant Alzheimer’s disease Alzheimers & Dementia. 11: 888. DOI: 10.1016/J.Jalz.2015.08.098  0.376
2015 Quiroz YT, Amariglio R, Aguirre-Acevedo DC, Opoka S, Pulsifer B, Jaimes SY, Castrillon G, Tirado V, Munoz C, Sperling RA, Lopera F. Associations between subjective memory complaints and hippocampal volume in preclinical early-onset Alzheimer's disease Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.06.972  0.413
2014 Herrera DA, Vargas J, Ochoa JF, Duque JE, Vargas SA, Lopera F, Castillo M. Alzheimer's disease: initial clinical implementation of automated volumetry. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 41: 651-3. PMID 25373817 DOI: 10.1017/cjn.2014.23  0.325
2014 Ryman DC, Acosta-Baena N, Aisen PS, Bird T, Danek A, Fox NC, Goate A, Frommelt P, Ghetti B, Langbaum JB, Lopera F, Martins R, Masters CL, Mayeux RP, McDade E, et al. Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis. Neurology. 83: 253-60. PMID 24928124 DOI: 10.1212/Wnl.0000000000000596  0.394
2014 Ayutyanont N, Langbaum JB, Hendrix SB, Chen K, Fleisher AS, Friesenhahn M, Ward M, Aguirre C, Acosta-Baena N, Madrigal L, Muñoz C, Tirado V, Moreno S, Tariot PN, Lopera F, et al. The Alzheimer's prevention initiative composite cognitive test score: sample size estimates for the evaluation of preclinical Alzheimer's disease treatments in presenilin 1 E280A mutation carriers. The Journal of Clinical Psychiatry. 75: 652-60. PMID 24816373 DOI: 10.4088/Jcp.13M08927  0.469
2014 Sepulveda-Falla D, Barrera-Ocampo A, Hagel C, Korwitz A, Vinueza-Veloz MF, Zhou K, Schonewille M, Zhou H, Velazquez-Perez L, Rodriguez-Labrada R, Villegas A, Ferrer I, Lopera F, Langer T, De Zeeuw CI, et al. Familial Alzheimer's disease-associated presenilin-1 alters cerebellar activity and calcium homeostasis. The Journal of Clinical Investigation. 124: 1552-67. PMID 24569455 DOI: 10.1172/Jci66407  0.791
2014 Rodriguez R, Lopera F, Alvarez A, Fernandez Y, Galan L, Quiroz Y, Bobes MA. Spectral Analysis of EEG in Familial Alzheimer's Disease with E280A Presenilin-1 Mutation Gene. International Journal of Alzheimer's Disease. 2014: 180741. PMID 24551475 DOI: 10.1155/2014/180741  0.454
2014 Lalli MA, Cox HC, Arcila ML, Cadavid L, Moreno S, Garcia G, Madrigal L, Reiman EM, Arcos-Burgos M, Bedoya G, Brunkow ME, Glusman G, Roach JC, Hood L, Kosik KS, ... Lopera F, et al. Origin of the PSEN1 E280A mutation causing early-onset Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: S277-S283.e10. PMID 24239249 DOI: 10.1016/J.Jalz.2013.09.005  0.465
2014 Londono AC, Castellanos FX, Arbelaez A, Ruiz A, Aguirre-Acevedo DC, Richardson AM, Easteal S, Lidbury BA, Arcos-Burgos M, Lopera F. An 1H-MRS framework predicts the onset of Alzheimer's disease symptoms in PSEN1 mutation carriers. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 552-61. PMID 24239247 DOI: 10.1016/J.Jalz.2013.08.282  0.493
2014 Tobon C, Duque JE, Ochoa JF, Hernandez M, Quiroz YT, Lopera F. Changes In Brain Network Measures In Pre-Symptomatic Alzheimer'S Disease With E280A Presenilin-1 Mutation Gene Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.07.047  0.433
2014 Tobon C, Duque JE, Aponte C, Ochoa JF, Munoz C, Hernandez M, Quiroz YT, Lopera F. Effect Of Ps-1 E280A Mutation Of Familial Alzheimer'S Disease On Quantitative Eeg In Asymptomatic Adults Alzheimers & Dementia. 10: 885. DOI: 10.1016/J.Jalz.2014.07.046  0.458
2014 Trujillo-Rodríguez DM, Sepúlveda-Falla D, Arboleda H, Glatzel M, Lopera F. Neuropathological, Neuropsychological, And Imagenological Comparison Between Sporadic Alzheimer'S Disease And Ps1-E280A Alzheimers & Dementia. 10: 476. DOI: 10.1016/J.Jalz.2014.05.689  0.789
2013 Langbaum JB, Fleisher AS, Chen K, Ayutyanont N, Lopera F, Quiroz YT, Caselli RJ, Tariot PN, Reiman EM. Ushering in the study and treatment of preclinical Alzheimer disease. Nature Reviews. Neurology. 9: 371-81. PMID 23752908 DOI: 10.1038/Nrneurol.2013.107  0.472
2013 Giraldo M, Lopera F, Siniard AL, Corneveaux JJ, Schrauwen I, Carvajal J, Muñoz C, Ramirez-Restrepo M, Gaiteri C, Myers AJ, Caselli RJ, Kosik KS, Reiman EM, Huentelman MJ. Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease. Neurobiology of Aging. 34: 2077.e11-8. PMID 23582655 DOI: 10.1016/J.Neurobiolaging.2013.02.016  0.529
2013 Quiroz YT, Stern CE, Reiman EM, Brickhouse M, Ruiz A, Sperling RA, Lopera F, Dickerson BC. Cortical atrophy in presymptomatic Alzheimer's disease presenilin 1 mutation carriers. Journal of Neurology, Neurosurgery, and Psychiatry. 84: 556-61. PMID 23134660 DOI: 10.1136/Jnnp-2012-303299  0.502
2013 Vélez JI, Chandrasekharappa SC, Henao E, Martinez AF, Harper U, Jones M, Solomon BD, Lopez L, Garcia G, Aguirre-Acevedo DC, Acosta-Baena N, Correa JC, Lopera-Gómez CM, Jaramillo-Elorza MC, Rivera D, ... ... Lopera F, et al. Pooling/bootstrap-based GWAS (pbGWAS) identifies new loci modifying the age of onset in PSEN1 p.Glu280Ala Alzheimer's disease. Molecular Psychiatry. 18: 568-75. PMID 22710270 DOI: 10.1038/Mp.2012.81  0.434
2013 Quiroz Y, Velilla LM, Giraldo M, Lopera F. Cognitive profiles of frontotemporal dementia and Alzheimer's disease in a Colombian sample: A preliminary investigation Alzheimers & Dementia. 9: 791. DOI: 10.1016/J.Jalz.2013.05.1626  0.32
2013 Lopera F, Giraldo M, Acosta N, Munoz C, Moreno S, Tirado V, Lopez L, Ospina GPG, Langbaum J, Ho C, Suliman S, Cho W, Tariot P, Reiman E. Alzheimer's Prevention Initiative Colombia registry in the PSEN1 E280A mutation kindred Alzheimers & Dementia. 9: 321. DOI: 10.1016/J.Jalz.2013.04.151  0.454
2013 Fleisher A, Chen K, Quiroz Y, Jakimovich L, Gutierrez M, Langbaum J, Roontiva A, Thiyyagura P, Luo J, Liu X, Lee W, Ayutyanont N, Parks S, Munoz C, Moreno S, ... ... Lopera F, et al. Pre-symptomatic functional brain changes in PS1 E280A mutation carriers compared to other biomarkers: Pilot data from the Alzheimer's Prevention Initiative Biomarker project Alzheimers & Dementia. 9: 3. DOI: 10.1016/J.Jalz.2013.04.016  0.344
2012 Fleisher AS, Chen K, Quiroz YT, Jakimovich LJ, Gomez MG, Langois CM, Langbaum JB, Ayutyanont N, Roontiva A, Thiyyagura P, Lee W, Mo H, Lopez L, Moreno S, Acosta-Baena N, ... ... Lopera F, et al. Florbetapir PET analysis of amyloid-β deposition in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional study. The Lancet. Neurology. 11: 1057-65. PMID 23137949 DOI: 10.1016/S1474-4422(12)70227-2  0.525
2012 Reiman EM, Quiroz YT, Fleisher AS, Chen K, Velez-Pardo C, Jimenez-Del-Rio M, Fagan AM, Shah AR, Alvarez S, Arbelaez A, Giraldo M, Acosta-Baena N, Sperling RA, Dickerson B, Stern CE, ... ... Lopera F, et al. Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study. The Lancet. Neurology. 11: 1048-56. PMID 23137948 DOI: 10.1016/S1474-4422(12)70228-4  0.5
2012 Lalli MA, Garcia G, Madrigal L, Arcos-Burgos M, Arcila ML, Kosik KS, Lopera F. Exploratory data from complete genomes of familial alzheimer disease age-at-onset outliers. Human Mutation. 33: 1630-4. PMID 22829467 DOI: 10.1002/Humu.22167  0.448
2012 Sepulveda-Falla D, Glatzel M, Lopera F. Phenotypic profile of early-onset familial Alzheimer's disease caused by presenilin-1 E280A mutation. Journal of Alzheimer's Disease : Jad. 32: 1-12. PMID 22766738 DOI: 10.3233/Jad-2012-120907  0.799
2012 MacPherson SE, Parra MA, Moreno S, Lopera F, Della Sala S. Dual task abilities as a possible preclinical marker of Alzheimer's disease in carriers of the E280A presenilin-1 mutation. Journal of the International Neuropsychological Society : Jins. 18: 234-41. PMID 22133015 DOI: 10.1017/S1355617711001561  0.413
2012 Chen K, Fleisher AS, Ayutyanont N, Langbaum JB, Caselli R, Quiroz YT, Lopera F, Tariot PN, Reiman EM. Brain imaging biomarkers for the Alzheimer’s Prevention Initiative Journal of Translational Medicine. 10. DOI: 10.1186/1479-5876-10-S2-A28  0.476
2012 Fleisher A, Quiroz Y, Chen K, Jakimovich L, Gutierrez M, Langbaum J, Roontiva A, Thiyyagura P, Liu X, Lee W, Ayutyanont N, Nishimura M, Parks S, Alvarez S, Munoz C, ... ... Lopera F, et al. Trajectory of age-associated structural changes in early-onset Alzheimer's disease, for the Alzheimer's Prevention Initiative Alzheimers & Dementia. 8: 16. DOI: 10.1016/J.Jalz.2012.05.2128  0.47
2012 Chen K, Quiroz Y, Jakimovich L, Gutierrez M, Langbaum J, Roontiva A, Thiyyagura P, Liu X, Lee W, Ayutyanont N, Nishimura M, Parks S, Alvarez S, Lopez L, Acosta-Baena N, ... ... Lopera F, et al. Age-associated trajectories of biomarkers in early-onset Alzheimer's disease, for the Alzheimer's Prevention Initiative Alzheimers & Dementia. 8: 85. DOI: 10.1016/J.Jalz.2012.05.205  0.485
2012 Chen K, Fleisher A, Ayutyanont N, Quiroz Y, Alvarez S, Lopera F, Reiman E. Mathematical and statistical methods to model the trajectory and estimate the age at onset of Alzheimer's disease biomarker changes Alzheimers & Dementia. 8: 72. DOI: 10.1016/J.Jalz.2012.05.170  0.385
2012 Tariot PN, Ho C, Langlois C, Reiman EM, Lopera F, Langbaum JB, Jakimovich L, Ayutyanont N, High N, Paul R, Suliman S, Romenets SR, Cho W. The Alzheimer'S Prevention Initiative Alzheimers & Dementia. 10: 247. DOI: 10.1016/J.Jalz.2012.05.1136  0.434
2012 Quiroz Y, Reiman E, Brickhouse M, Chen K, Fleisher A, Munoz C, Langbaum J, Alvarez S, Tariot P, Lopera F, Dickerson B. Trajectory of the Alzheimer's-signature MRI biomarker in familial Alzheimer's disease, for the Alzheimer's Prevention Initiative Alzheimers & Dementia. 8: 36. DOI: 10.1016/J.Jalz.2012.05.092  0.48
2012 Quiroz Y, Willment K, Muniz M, Ruiz A, Castrillon G, Lopera F, Stern C. Encoding of novel complex visual scenes in presymptomatic Alzheimer's disease Alzheimers & Dementia. 8: 35. DOI: 10.1016/J.Jalz.2012.05.091  0.391
2011 Quiroz YT, Lopera F, Budson AE. Charting the path for early diagnosis and prevention of Alzheimer's disease. Expert Review of Neurotherapeutics. 11: 1665-7. PMID 22091590 DOI: 10.1586/Ern.11.162  0.446
2011 Reiman EM, Langbaum JB, Fleisher AS, Caselli RJ, Chen K, Ayutyanont N, Quiroz YT, Kosik KS, Lopera F, Tariot PN. Alzheimer's Prevention Initiative: a plan to accelerate the evaluation of presymptomatic treatments. Journal of Alzheimer's Disease : Jad. 26: 321-9. PMID 21971471 DOI: 10.3233/Jad-2011-0059  0.457
2011 Quiroz YT, Ally BA, Celone K, McKeever J, Ruiz-Rizzo AL, Lopera F, Stern CE, Budson AE. Event-related potential markers of brain changes in preclinical familial Alzheimer disease. Neurology. 77: 469-75. PMID 21775732 DOI: 10.1212/Wnl.0B013E318227B1B0  0.479
2011 Arboleda-Velasquez JF, Manent J, Lee JH, Tikka S, Ospina C, Vanderburg CR, Frosch MP, Rodríguez-Falcón M, Villen J, Gygi S, Lopera F, Kalimo H, Moskowitz MA, Ayata C, Louvi A, et al. Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease. Proceedings of the National Academy of Sciences of the United States of America. 108: E128-35. PMID 21555590 DOI: 10.1073/Pnas.1101964108  0.368
2011 Parra MA, Sala SD, Abrahams S, Logie RH, Méndez LG, Lopera F. Specific deficit of colour-colour short-term memory binding in sporadic and familial Alzheimer's disease. Neuropsychologia. 49: 1943-52. PMID 21435348 DOI: 10.1016/J.Neuropsychologia.2011.03.022  0.468
2011 Acosta-Baena N, Sepulveda-Falla D, Lopera-Gómez CM, Jaramillo-Elorza MC, Moreno S, Aguirre-Acevedo DC, Saldarriaga A, Lopera F. Pre-dementia clinical stages in presenilin 1 E280A familial early-onset Alzheimer's disease: a retrospective cohort study. The Lancet. Neurology. 10: 213-20. PMID 21296022 DOI: 10.1016/S1474-4422(10)70323-9  0.743
2011 Sepulveda-Falla D, Matschke J, Bernreuther C, Hagel C, Puig B, Villegas A, Garcia G, Zea J, Gomez-Mancilla B, Ferrer I, Lopera F, Glatzel M. Deposition of hyperphosphorylated tau in cerebellum of PS1 E280A Alzheimer's disease. Brain Pathology (Zurich, Switzerland). 21: 452-63. PMID 21159009 DOI: 10.1111/J.1750-3639.2010.00469.X  0.775
2011 Parra M, Sala SD, Logie RH, Lopera F. Working memory binding: a cognitive marker for Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.856  0.393
2011 Moreno S, Parra MA, MacPherson SE, Lopera F, Sala SD, Logie RH. Working memory binding and dual-tasking can mark onset and progression of Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.730  0.429
2011 Reiman E, Velez-Pardo C, Rio MJd, Giraldo M, Acosta-Baena N, Kosik K, Shah A, Quiroz Y, Chen K, Fagan A, Langbaum J, Tariot P, Lopera F, Fleisher A. Elevated cerebrospinal fluid amyloid-Beta42 levels in young adults at genetic risk for early-onset alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.253  0.405
2011 Ayutyanont N, Lopera F, Hendrix S, Langbaum J, Madrigal L, Moreno S, Tirado V, Munoz C, Henao E, Ruiz A, Aguirre C, Quiroz Y, Fleisher A, Chen K, Langlois C, et al. Composite cognitive endpoints with improved power to detect presymptomatic Alzheimer's disease treatment effects: Findings in the Colombian kindred with the E280A Presenilin 1 mutation and the Alzheimer's Prevention Initiative Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1729  0.471
2011 Quiroz Y, Sperling R, Lopera F, Fleisher A, Chen K, Tirado V, Munoz C, Langbaum J, Tariot P, Stern C, Reiman E. IC-P-066: Task-dependent fMRI abnormalities in young adults at genetic risk for early-onset Alzheimer's disease Alzheimer's & Dementia. 7: S34-S35. DOI: 10.1016/J.Jalz.2011.05.132  0.368
2011 Fleisher A, Quiroz Y, Chen K, Langbaum J, Thiyyagura P, Liu X, Lee W, Roontiva A, Ruiz A, Tariot P, Lopera F, Reiman E. Reduced regional gray matter in cognitively normal young adults at genetic risk for early-onset Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.063  0.391
2011 Quiroz Y, Stern C, Reiman E, Brickhouse M, Moreno S, Henao E, Sperling R, Lopera F, Dickerson B. Cortical signature of alzheimer's disease-related thinning in presymptomatic presenilin-1 mutation carriers Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.016  0.476
2010 Quiroz YT, Budson AE, Celone K, Ruiz A, Newmark R, Castrillón G, Lopera F, Stern CE. Hippocampal hyperactivation in presymptomatic familial Alzheimer's disease. Annals of Neurology. 68: 865-75. PMID 21194156 DOI: 10.1002/Ana.22105  0.496
2010 Parra MA, Abrahams S, Logie RH, Méndez LG, Lopera F, Della Sala S. Visual short-term memory binding deficits in familial Alzheimer's disease. Brain : a Journal of Neurology. 133: 2702-13. PMID 20624814 DOI: 10.1093/Brain/Awq148  0.433
2010 Bobes MA, García YF, Lopera F, Quiroz YT, Galán L, Vega M, Trujillo N, Valdes-Sosa M, Valdes-Sosa P. ERP generator anomalies in presymptomatic carriers of the Alzheimer's disease E280A PS-1 mutation. Human Brain Mapping. 31: 247-65. PMID 19650138 DOI: 10.1002/Hbm.20861  0.43
2010 Dorfman VB, Pasquini L, Riudavets M, López-Costa JJ, Villegas A, Troncoso JC, Lopera F, Castaño EM, Morelli L. Differential cerebral deposition of IDE and NEP in sporadic and familial Alzheimer's disease. Neurobiology of Aging. 31: 1743-57. PMID 19019493 DOI: 10.1016/J.Neurobiolaging.2008.09.016  0.448
2010 Moreno S, Garcia G, Saldarriaga A, Sepulveda-Falla D, Arboleda J, Kosik K, Lopera F. Genotype - phenotype correlation in CADASIL. Cognitive performance in carriers of notch3 mutations R1031C and C455R International Journal of Psychological Research. 3: 109-122. DOI: 10.21500/20112084.817  0.706
2010 Moreno S, Buriticá O, Franco A, Pineda N, Arias W, Sepúlveda D, Aguirre C, Tamayo W, Uribe S, Bedoya G, Ruiz-Linares A, Lopera F. Cognitive alterations in juvenile Parkinson´s disease caused by the C212Y mutation in the Parkin gene. International Journal of Psychological Research. 3: 55-62. DOI: 10.21500/20112084.812  0.432
2009 Quiroz YT, Stern CE, Lopera F, McKeever JD, Ally BA, Ruiz A, Budson AE. IC-P-048: Using high density event-related potentials to study recognition memory in presymptomatic individuals with familial Alzheimer's disease due to E280A presenilin-1 mutation Alzheimer's & Dementia. 5: P23-P24. DOI: 10.1016/J.Jalz.2009.05.068  0.407
2009 Quiroz YT, Budson AE, Lopera F, Celone K, Schon K, Ruiz A, Cooper S, Newmark R, Stern CE. IC-P-047: Distinct activation patterns for associative encoding in presymptomatic individuals with familial Alzheimer's disease due to E280A presenilin-1 mutation Alzheimer's & Dementia. 5: P23-P23. DOI: 10.1016/J.Jalz.2009.05.067  0.432
2008 Van Vickle GD, Esh CL, Kokjohn TA, Patton RL, Kalback WM, Luehrs DC, Beach TG, Newel AJ, Lopera F, Ghetti B, Vidal R, Castaño EM, Roher AE. Presenilin-1 280Glu-->Ala mutation alters C-terminal APP processing yielding longer abeta peptides: implications for Alzheimer's disease. Molecular Medicine (Cambridge, Mass.). 14: 184-94. PMID 18317569 DOI: 10.2119/2007-00094.Vanvickle  0.41
2008 Fernández Nin A, Fernández Y, Bobes León M, Lopera F, Quiroz Y, Ortiz Z, Leyva Medrano L, Feria M. 96. Early detection of Alzheimer disease: Electrophysiological markers based on the n400 component of the evoked related potential Clinical Neurophysiology. 119: e123. DOI: 10.1016/J.Clinph.2008.04.112  0.358
2008 Fernández Garcı´a Y, Bobes León M, Ruiz López E, Lopera F, Quiroz Y, Fernández Nin A, Iturria Y, Alemán Y. 16. ERPs and MRI study in early stage of Alzheimer’s disease Clinical Neurophysiology. 119: e103. DOI: 10.1016/J.Clinph.2008.04.032  0.315
2007 Aguirre-Acevedo DC, Gómez RD, Moreno S, Henao-Arboleda E, Motta M, Muñoz C, Arana A, Pineda DA, Lopera F. [Validity and reliability of the CERAD-Col neuropsychological battery]. Revista De Neurologia. 45: 655-60. PMID 18050096  0.303
2007 Arango-Lasprilla JC, Cuetos F, Valencia C, Uribe C, Lopera F. Cognitive changes in the preclinical phase of familial Alzheimer's disease. Journal of Clinical and Experimental Neuropsychology. 29: 892-900. PMID 17852592 DOI: 10.1080/13803390601174151  0.492
2007 Cuetos F, Arango-Lasprilla JC, Uribe C, Valencia C, Lopera F. Linguistic changes in verbal expression: a preclinical marker of Alzheimer's disease. Journal of the International Neuropsychological Society : Jins. 13: 433-9. PMID 17445292 DOI: 10.1017/S1355617707070609  0.476
2007 Villegas A, Castañeda MM, Arias LF, Vieco B, Lopera F, Bedoya G. Evaluation of amyloid-b by the E280A mutation in presenilin gene Biomedica. 27: 372-384. DOI: 10.7705/Biomedica.V27I3.200  0.395
2006 Pineda-Trujillo N, Apergi M, Moreno S, Arias W, Lesage S, Franco A, Sepulveda-Falla D, Cano D, Buriticá O, Pineda D, Uribe CS, de Yebenes JG, Lees AJ, Brice A, Bedoya G, ... Lopera F, et al. A genetic cluster of early onset Parkinson's disease in a Colombian population. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 885-9. PMID 16941654 DOI: 10.1002/Ajmg.B.30375  0.691
2006 Muñoz AM, Agudelo GM, Lopera FJ. [Nutritional condition in patients with Alzheimer-type dementia from the neurosciences' group, Medellín 2004]. Biomã©Dica : Revista Del Instituto Nacional De Salud. 26: 113-25. PMID 16929909  0.354
2006 Bustamante J, Lopera F. [Tumour of the corpus callosum: the association between interhemispheric disconnection and an anterograde amnesia syndrome]. Revista De Neurologia. 43: 207-12. PMID 16883509  0.407
2006 Arango-Lasprilla JC, Rogers H, Lengenfelder J, Deluca J, Moreno S, Lopera F. Cortical and subcortical diseases: do true neuropsychological differences exist? Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists. 21: 29-40. PMID 16143493 DOI: 10.1016/J.Acn.2005.07.004  0.418
2006 Muñoz AM, Agudelo GM, Lopera FJ. Diagnóstico del estado nutricional de los pacientes con demencia tipo Alzheimer registrados en el Grupo de Neurociencias, Medellín, 2004. BioméDica. 26: 113. DOI: 10.7705/BIOMEDICA.V26I1.1400  0.371
2006 Bustamante J, Lopera F. Tumor del cuerpo calloso: asociación de la desconexión interhemisférica con un síndrome de amnesia anterógrada Revista De Neurologia. 43: 207-212. DOI: 10.33588/Rn.4304.2005626  0.412
2006 Quiroz YT, Sperling RA, Lopera F, Baena A, Alvarez S, Guzman-Velez E, Pardilla-Delgado E, Arboleda-Velasquez J, Gatchel JR, Fuller J, Artola A, Schultz AP, Chen K, Tariot PN, Reiman EM, et al. P4-299: TAU ACCUMULATION IN THE ENTORHINAL CORTEX AND PRECUNEUS IS ASSOCIATED WITH CORTICAL AMYLOID-BETA BURDEN, AGE AND WORSE MEMORY PERFORMANCE IN PRECLINICAL AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1567-P1567. DOI: 10.1016/J.Jalz.2018.07.121  0.447
2006 Sanchez JS, Sperling RA, Lopera F, Augustinack J, Becker A, Jacobs HI, Jin D, Katz S, Luner E, Moody K, Price JC, Guzman-Velez E, Baena A, Pardilla-Delgado E, Chen K, et al. IC-P-215: TAU ACCUMULATION IN RHINAL CORTEX IS ASSOCIATED WITH MEMORY PERFORMANCE IN NON-DEMENTED YOUNG ADULTS WITH AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P176-P177. DOI: 10.1016/J.Jalz.2018.06.2282  0.401
2006 Hanseeuw BJ, Lopera F, Sperling RA, Norton D, Guzman-Velez E, Baena A, Schultz AP, Gatchel JR, Chen K, Reiman EM, Johnson KA, Quiroz YT. IC-P-140: TAU ACCUMULATION AND MEMORY DECLINE ARE MORE CLOSELY RELATED TO STRIATAL THAN CORTICAL AMYLOIDOSIS IN INDIVIDUALS WITH EARLY-ONSET AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P117-P117. DOI: 10.1016/J.Jalz.2018.06.2206  0.437
2006 Quiroz YT, Aguero C, Lopera F, Norton DJ, Aguirre-Acevedo DC, Chen K, Baena A, Gatchel JR, Guzman-Velez E, Pardilla-Delgado E, Artola A, Alvarez S, Sperling RA, Reiman EM, Johnson KA. P3-399: ASSOCIATION BETWEEN CORTICAL THINNING AND TAU PATHOLOGY IN PRECLINICAL AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1253-P1254. DOI: 10.1016/J.Jalz.2018.06.1761  0.476
2006 Jacobs HI, Lopera F, Sperling RA, Norton D, Guzman-Velez E, Baena A, Pardilla-Delgado E, Gatchel JR, Chen K, Reiman EM, Johnson KA, Quiroz YT. P2-461: ENTORHINAL TAU PATHOLOGY IS ASSOCIATED WITH WHITE MATTER ABNORMALITIES IN UNCINATE FASCICULUS IN PRECLINICAL AUTOSOMAL DOMINANT ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P897-P898. DOI: 10.1016/J.Jalz.2018.06.1154  0.46
2004 Tirado V, Muñoz C, Aguirre C, Pineda DA, Lopera F. [Performance of carriers and non-carriers of the E280A mutation for familial Alzheimer's disease in a naming test]. Revista De Neurologia. 39: 322-6. PMID 15340889 DOI: 10.33588/Rn.3904.2004037  0.409
2004 Velez-Pardo C, Rio MJ, Moreno S, Ramírez-Gomez L, Correa G, Lopera F. New mutation (T1232P) of the ATP-7B gene associated with neurologic and neuropsychiatric dominance onset of Wilson's disease in three unrelated Colombian kindred. Neuroscience Letters. 367: 360-4. PMID 15337266 DOI: 10.1016/J.Neulet.2004.06.032  0.354
2004 Velez-Pardo C, Arellano JI, Cardona-Gomez P, Jimenez Del Rio M, Lopera F, De Felipe J. CA1 hippocampal neuronal loss in familial Alzheimer's disease presenilin-1 E280A mutation is related to epilepsy. Epilepsia. 45: 751-6. PMID 15230697 DOI: 10.1111/J.0013-9580.2004.55403.X  0.348
2003 Mejía S, Giraldo M, Pineda D, Ardila A, Lopera F. Nongenetic factors as modifiers of the age of onset of familial Alzheimer's disease. International Psychogeriatrics / Ipa. 15: 337-49. PMID 15000414 DOI: 10.1017/S1041610203009591  0.403
2003 Pastor P, Roe CM, Villegas A, Bedoya G, Chakraverty S, García G, Tirado V, Norton J, Ríos S, Martínez M, Kosik KS, Lopera F, Goate AM. Apolipoprotein Eepsilon4 modifies Alzheimer's disease onset in an E280A PS1 kindred. Annals of Neurology. 54: 163-9. PMID 12891668 DOI: 10.1002/Ana.10636  0.49
2003 Arango Lasprilla JC, Iglesias J, Lopera F. Neuropsychological study of familial Alzheimer's disease caused by mutation E280A in the presenilin 1 gene. American Journal of Alzheimer's Disease and Other Dementias. 18: 137-46. PMID 12811988 DOI: 10.1177/153331750301800306  0.506
2003 García A, Lopera F, Madrigal L, Ossa J. Towards the enunciation of ethical dilemmas regarding early onset Alzheimer's disease in Antioquia, Colombia | Hacia el enunciado de dilemas éticos sobre la enfermedad de Alzheimer precoz, en Antioquia, Colombia Iatreia. 16: 174-182.  0.395
2002 Arboleda-Velasquez JF, Lopera F, Lopez E, Frosch MP, Sepulveda-Falla D, Gutierrez JE, Vargas S, Medina M, Martinez De Arrieta C, Lebo RV, Slaugenhaupt SA, Betensky RA, Villegas A, Arcos-Burgos M, Rivera D, et al. C455R notch3 mutation in a Colombian CADASIL kindred with early onset of stroke. Neurology. 59: 277-9. PMID 12136071 DOI: 10.1212/Wnl.59.2.277  0.675
2001 Velez-Pardo C, Arroyave ST, Lopera F, Castaño AD, Jimenez Del Rio M. Ultrastructure evidence of necrotic neural cell death in familial Alzheimer's disease brains bearing presenilin-1 E280A mutation. Journal of Alzheimer's Disease : Jad. 3: 409-415. PMID 12214045 DOI: 10.3233/Jad-2001-3408  0.353
2001 Johnson KA, Lopera F, Jones K, Becker A, Sperling R, Hilson J, Londono J, Siegert I, Arcos M, Moreno S, Madrigal L, Ossa J, Pineda N, Ardila A, Roselli M, et al. Presenilin-1-associated abnormalities in regional cerebral perfusion. Neurology. 56: 1545-51. PMID 11402113 DOI: 10.1212/Wnl.56.11.1545  0.406
2001 Lopera F, Rivera N, Arboleda J, Restrepo T, Arcos-Burgos M. [Analysis of complex segregation in a large family with hereditary cerebrovascular disease in Antioquia, Colombia]. Revista De Neurologia. 32: 222-5. PMID 11310272 DOI: 10.33588/Rn.3203.2000427  0.428
2001 Pineda-Trujillo N, Carvajal-Carmona LG, Buriticá O, Moreno S, Uribe C, Pineda D, Toro M, García F, Arias W, Bedoya G, Lopera F, Ruiz-Linares A. A novel Cys212Tyr founder mutation in parkin and allelic heterogeneity of juvenile Parkinsonism in a population from North West Colombia. Neuroscience Letters. 298: 87-90. PMID 11163284 DOI: 10.1016/S0304-3940(00)01733-X  0.356
2000 Ardila A, Lopera F, Rosselli M, Moreno S, Madrigal L, Arango-Lasprilla JC, Arcos M, Murcia C, Arango-Viana JC, Ossa J, Goate A, Kosik KS. Neuropsychological profile of a large kindred with familial Alzheimer's disease caused by the E280A single presenilin-1 mutation. Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists. 15: 515-28. PMID 14590205 DOI: 10.1093/Arclin/15.6.515  0.351
2000 Velez-Pardo C, Lopera F, Jimenez Del Rio M. DNA Damage does not Correlate with Amyloid-beta-Plaques and Neurofibrillary Tangles in Familial Alzheimer's Disease Presenilin-1 [E280A] Mutation. Journal of Alzheimer's Disease : Jad. 2: 47-57. PMID 12214110 DOI: 10.3233/Jad-2000-2106  0.456
2000 Velásquez M, Arcos-Burgos M, Toro ME, Castaño A, Madrigal L, Moreno S, Jaramillo N, Lopera F. [Factorial and discriminant analyses of neuropsychological variables in familial and sporadic late onset Alzheimer disease]. Revista De Neurologia. 31: 501-6. PMID 11055049 DOI: 10.1016/S0197-4580(00)83367-9  0.397
2000 Rosselli MC, Ardila AC, Moreno SC, Standish VC, Arango-Lasprilla JC, Tirado VM, Ossa JM, Goate AM, Kosik KS, Lopera F. Cognitive decline in patients with familial Alzheimer's disease associated with E280a presenilin-1 mutation: a longitudinal study. Journal of Clinical and Experimental Neuropsychology. 22: 483-95. PMID 10923058 DOI: 10.1076/1380-3395(200008)22:4;1-0;Ft483  0.375
2000 Velez-Pardo C, Lopera F, Jimenez Del Rio M. DNA damage does not correlate with amyloid-β-plaques and neurofibrillary tangles in familial Alzheimer's disease presenilin-1 [E280A] mutation Journal of Alzheimer's Disease. 2: 47-57.  0.343
1999 Toro F, Lopera F, Ossa J, Madrigal L, Mira A, Díaz A, Parra S. [Detection of antibodies to beta-amyloid in carriers of E280A mutation in the presenilin-1 gene]. Revista De Neurologia. 29: 1104-7. PMID 10652730  0.322
1999 Lopera F, Tobón N, Arcos-Burgos M, Vargas S, Gutiérrez JE, Rosselli M, Ardila A. [Image characterization of Alzheimer's disease associated with the E280A-PS1 mutation. Case-control study: MRI findings]. Revista De Neurologia. 29: 6-12. PMID 10528301  0.309
1999 Duque-Castaño A, Roldán MI, Arango-Viana JC, Arcos-Burgos M, Cubillo H, Lopera F. [Neuropathological findings in early-onset Alzheimer's disease (E280a-PS1 mutation)]. Revista De Neurologia. 29: 1-6. PMID 10528300  0.379
1999 Gómez-Isla T, Growdon WB, McNamara MJ, Nochlin D, Bird TD, Arango JC, Lopera F, Kosik KS, Lantos PL, Cairns NJ, Hyman BT. The impact of different presenilin 1 andpresenilin 2 mutations on amyloid deposition, neurofibrillary changes and neuronal loss in the familial Alzheimer's disease brain: evidence for other phenotype-modifying factors. Brain : a Journal of Neurology. 122: 1709-19. PMID 10468510 DOI: 10.1093/Brain/122.9.1709  0.515
1999 Rosselli M, Lopera F, Ardila A, Moreno S, Standish V. Cognitive decline in patients with familial Alzheimer's disease associated with a single preseniline 1 mutation: A longitudinal study Archives of Clinical Neuropsychology. 14: 620-621. DOI: 10.1016/S0887-6177(99)80009-2  0.479
1998 Velez-Pardo C, Jimenez Del Rio M, Lopera F. Familial Alzheimer's disease: oxidative stress, beta-amyloid, presenilins, and cell death. General Pharmacology. 31: 675-81. PMID 9809462 DOI: 10.1016/S0306-3623(98)00189-X  0.447
1997 Lendon CL, Martinez A, Behrens IM, Kosik KS, Madrigal L, Norton J, Neuman R, Myers A, Busfield F, Wragg M, Arcos M, Arango Viana JC, Ossa J, Ruiz A, Goate AM, ... Lopera F, et al. E280A PS-1 mutation causes Alzheimer's disease but age of onset is not modified by ApoE alleles. Human Mutation. 10: 186-95. PMID 9298817 DOI: 10.1002/(Sici)1098-1004(1997)10:3<186::Aid-Humu2>3.0.Co;2-H  0.505
1997 Lopera F, Ardilla A, Martínez A, Madrigal L, Arango-Viana JC, Lemere CA, Arango-Lasprilla JC, Hincapíe L, Arcos-Burgos M, Ossa JE, Behrens IM, Norton J, Lendon C, Goate AM, Ruiz-Linares A, et al. Clinical features of early-onset Alzheimer disease in a large kindred with an E280A presenilin-1 mutation. Jama. 277: 793-9. PMID 9052708 DOI: 10.1016/S0002-9394(14)71677-0  0.487
1996 Lemere CA, Lopera F, Kosik KS, Lendon CL, Ossa J, Saido TC, Yamaguchi H, Ruiz A, Martinez A, Madrigal L, Hincapie L, Arango JC, Anthony DC, Koo EH, Goate AM, et al. The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology. Nature Medicine. 2: 1146-50. PMID 8837617 DOI: 10.1038/Nm1096-1146  0.368
1996 Lemere CA, Lopera F, Kosikl KS, Ossa J, Saido TC, Ruiz A, Martinez A, Madrigol L, Hincapie L, Selkoe DJ. 68 Immunocytochemical characterization of plaques, tangles and vascular amyloid in the brains of 2 FAD patients with an identified psi mutation Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80070-4  0.397
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