Stephanie A. Leavitt, Ph.D. - Publications

Affiliations: 
2006 Johns Hopkins University, Baltimore, MD 
Area:
General Biophysics

15 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Velazquez-Campoy A, Leavitt SA, Freire E. Characterization of protein-protein interactions by isothermal titration calorimetry. Methods in Molecular Biology (Clifton, N.J.). 1278: 183-204. PMID 25859950 DOI: 10.1007/978-1-4939-2425-7_11  0.84
2014 Lazerwith SE, Lew W, Zhang J, Morganelli P, Liu Q, Canales E, Clarke MO, Doerffler E, Byun D, Mertzman M, Ye H, Chong L, Xu L, Appleby T, Chen X, ... ... Leavitt SA, et al. Discovery of GS-9669, a thumb site II non-nucleoside inhibitor of NS5B for the treatment of genotype 1 chronic hepatitis C infection. Journal of Medicinal Chemistry. 57: 1893-901. PMID 24144213 DOI: 10.1021/jm401420j  0.84
2013 Fenaux M, Eng S, Leavitt SA, Lee YJ, Mabery EM, Tian Y, Byun D, Canales E, Clarke MO, Doerffler E, Lazerwith SE, Lew W, Liu Q, Mertzman M, Morganelli P, et al. Preclinical characterization of GS-9669, a thumb site II inhibitor of the hepatitis C virus NS5B polymerase. Antimicrobial Agents and Chemotherapy. 57: 804-10. PMID 23183437 DOI: 10.1128/AAC.02052-12  0.84
2012 Clarke MO, Byun D, Chen X, Doerffler E, Leavitt SA, Sheng XC, Yang CY, Kim CU. Novel, potent and orally bioavailable indolizidinone-derived inhibitors of the hepatitis C virus NS3 protease. Bioorganic & Medicinal Chemistry Letters. 22: 1095-8. PMID 22189140 DOI: 10.1016/j.bmcl.2011.11.107  0.84
2011 Lansdon EB, Liu Q, Leavitt SA, Balakrishnan M, Perry JK, Lancaster-Moyer C, Kutty N, Liu X, Squires NH, Watkins WJ, Kirschberg TA. Structural and binding analysis of pyrimidinol carboxylic acid and N-hydroxy quinazolinedione HIV-1 RNase H inhibitors. Antimicrobial Agents and Chemotherapy. 55: 2905-15. PMID 21464257 DOI: 10.1128/AAC.01594-10  0.84
2011 Callebaut C, Stray K, Tsai L, Williams M, Yang ZY, Cannizzaro C, Leavitt SA, Liu X, Wang K, Murray BP, Mulato A, Hatada M, Priskich T, Parkin N, Swaminathan S, et al. In vitro characterization of GS-8374, a novel phosphonate-containing inhibitor of HIV-1 protease with a favorable resistance profile. Antimicrobial Agents and Chemotherapy. 55: 1366-76. PMID 21245449 DOI: 10.1128/AAC.01183-10  0.84
2010 Khaki AR, Field C, Malik S, Niedziela-Majka A, Leavitt SA, Wang R, Hung M, Sakowicz R, Brendza KM, Fischer CJ. The macroscopic rate of nucleic acid translocation by hepatitis C virus helicase NS3h is dependent on both sugar and base moieties. Journal of Molecular Biology. 400: 354-78. PMID 20451531 DOI: 10.1016/j.jmb.2010.04.065  0.84
2006 Cihlar T, He GX, Liu X, Chen JM, Hatada M, Swaminathan S, McDermott MJ, Yang ZY, Mulato AS, Chen X, Leavitt SA, Stray KM, Lee WA. Suppression of HIV-1 protease inhibitor resistance by phosphonate-mediated solvent anchoring. Journal of Molecular Biology. 363: 635-47. PMID 16979654 DOI: 10.1016/j.jmb.2006.07.073  0.84
2004 Bacha U, Barrila J, Velazquez-Campoy A, Leavitt SA, Freire E. Identification of novel inhibitors of the SARS coronavirus main protease 3CLpro. Biochemistry. 43: 4906-12. PMID 15109248 DOI: 10.1021/bi0361766  0.84
2004 Velazquez-Campoy A, Leavitt SA, Freire E. Characterization of protein-protein interactions by isothermal titration calorimetry. Methods in Molecular Biology (Clifton, N.J.). 261: 35-54. PMID 15064448 DOI: 10.1385/1-59259-762-9:035  0.84
2004 Leavitt SA, SchOn A, Klein JC, Manjappara U, Chaiken IM, Freire E. Interactions of HIV-1 proteins gp120 and Nef with cellular partners define a novel allosteric paradigm. Current Protein & Peptide Science. 5: 1-8. PMID 14965316 DOI: 10.2174/1389203043486955  0.84
2002 Kwong PD, Doyle ML, Casper DJ, Cicala C, Leavitt SA, Majeed S, Steenbeke TD, Venturi M, Chaiken I, Fung M, Katinger H, Parren PWIH, Robinson J, Van Ryk D, Wang L, et al. HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites Nature. 420: 678-682. PMID 12478295 DOI: 10.1038/nature01188  0.84
2002 Luque I, Leavitt SA, Freire E. The linkage between protein folding and functional cooperativity: two sides of the same coin? Annual Review of Biophysics and Biomolecular Structure. 31: 235-56. PMID 11988469 DOI: 10.1146/annurev.biophys.31.082901.134215  0.84
2000 Summerhill E, Leavitt SA, Gidley H, Parry R, Solway J, Ober C. beta(2)-adrenergic receptor Arg16/Arg16 genotype is associated with reduced lung function, but not with asthma, in the Hutterites. American Journal of Respiratory and Critical Care Medicine. 162: 599-602. PMID 10934093 DOI: 10.1164/ajrccm.162.2.9910108  0.84
2000 Ober C, Leavitt SA, Tsalenko A, Howard TD, Hoki DM, Daniel R, Newman DL, Wu X, Parry R, Lester LA, Solway J, Blumenthal M, King RA, Xu J, Meyers DA, et al. Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations. American Journal of Human Genetics. 66: 517-26. PMID 10677312 DOI: 10.1086/302781  0.84
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