Zhiyan Xiao, Ph.D. - Publications

Affiliations: 
2003 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pharmacy

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Cao H, Xiao Z, Zhang Y, Kwong T, Danish SF, Weiner J, Wang X, Yue N, Dai Z, Kuang Y, Bai Y, Nie K. Dosimetric comparisons of different hypofractionated stereotactic radiotherapy techniques in treating intracranial tumors > 3 cm in longest diameter. Journal of Neurosurgery. 1-9. PMID 30901747 DOI: 10.3171/2018.12.JNS181578  0.36
2018 Huang Q, Jabbour SK, Xiao Z, Yue N, Wang X, Cao H, Kuang Y, Zhang Y, Nie K. Dosimetric feasibility of 4DCT-ventilation imaging guided proton therapy for locally advanced non-small-cell lung cancer. Radiation Oncology (London, England). 13: 78. PMID 29695284 DOI: 10.1186/s13014-018-1018-x  0.36
2018 Jing L, Tang Y, Goto M, Lee KH, Xiao Z. SAR study on ,-disubstituted pyrimidine-2,4-diamines as effective CDK2/CDK9 inhibitors and antiproliferative agents. Rsc Advances. 8: 11871-11885. PMID 29682280 DOI: 10.1039/c8ra01440j  0.88
2018 Xiao Z, Zou WJ, Chen T, Yue NJ, Jabbour SK, Parikh R, Zhang M. Using gEUD based plan analysis method to evaluate proton vs. photon plans for lung cancer radiation therapy. Journal of Applied Clinical Medical Physics. PMID 29436163 DOI: 10.1002/acm2.12281  0.36
2017 Zhou A, Yan L, Lai F, Chen X, Goto M, Lee KH, Xiao Z. Design, synthesis and biological evaluation of novel indolin-2-ones as potent anticancer compounds. Bioorganic & Medicinal Chemistry Letters. PMID 28625363 DOI: 10.1016/j.bmcl.2017.06.019  0.88
2015 Fang C, Xiao Z. Receptor-based 3D-QSAR in Drug Design: Methods and Applications in Kinase Studies. Current Topics in Medicinal Chemistry. PMID 26369822  0.88
2015 Xiao Z, Morris-Natschke SL, Lee KH. Strategies for the Optimization of Natural Leads to Anticancer Drugs or Drug Candidates. Medicinal Research Reviews. PMID 26359649 DOI: 10.1002/med.21377  0.88
2015 Xu K, Wang K, Yang Y, Yan DA, Huang L, Chen CH, Xiao Z. Discovery of novel non-covalent inhibitors selective to the β5-subunit of the human 20S proteasome. European Journal of Medicinal Chemistry. 98: 61-8. PMID 26005024 DOI: 10.1016/j.ejmech.2015.05.023  0.4
2015 Gao J, Fang C, Xiao Z, Huang L, Chen CH, Wang LT, Lee KH. Discovery of novel 5-fluoro-N (2),N (4)-diphenylpyrimidine-2,4-diamines as potent inhibitors against CDK2 and CDK9. Medchemcomm. 6: 444-454. PMID 25914804 DOI: 10.1039/C4MD00412D  0.88
2015 Xiao Z, Mazur TR, Driewer JP, Li HH. The role of oxygen in the photostimulation luminescence process of europium doped potassium chloride. Radiation Measurements. 76: 23-28. PMID 25897274 DOI: 10.1016/j.radmeas.2015.03.013  0.64
2014 Wu SY, Pan SL, Xiao ZY, Hsu JL, Chen MC, Lee KH, Teng CM. NPRL-Z-1, as a new topoisomerase II poison, induces cell apoptosis and ROS generation in human renal carcinoma cells. Plos One. 9: e112220. PMID 25372714 DOI: 10.1371/journal.pone.0112220  0.88
2014 Xiao Z, Hansel R, Zhang L, Li HH. Temperature dependence of the photostimulated luminescence in KCl:Eu(2+) Nuclear Instruments & Methods in Physics Research. Section B, Beam Interactions With Materials and Atoms. 326: 182-184. PMID 24778461 DOI: 10.1016/j.nimb.2013.09.031  0.64
2014 Hansel RA, Xiao Z, Zhang L, Li HH. X ray storage performance of KCl:Eu(2+) with high cumulated dose. Nuclear Instruments & Methods in Physics Research. Section B, Beam Interactions With Materials and Atoms. 326: 178-181. PMID 24778460 DOI: 10.1016/j.nimb.2013.08.067  0.64
2014 Li HH, Driewer JP, Han Z, Low DA, Yang D, Xiao Z. Two-dimensional high spatial-resolution dosimeter using europium doped potassium chloride: a feasibility study. Physics in Medicine and Biology. 59: 1899-909. PMID 24651448 DOI: 10.1088/0031-9155/59/8/1899  0.64
2014 Tang YB, Liu JZ, Zhang SE, Du X, Nie F, Tian JY, Ye F, Huang K, Hu JP, Li Y, Xiao Z. 3-Phenylpropanoic acid-based phosphotyrosine (pTyr) mimetics: hit evolution to a novel orally active protein tyrosine phosphatase 1B (PTP1B) inhibitor. Chemmedchem. 9: 918-21. PMID 24644278 DOI: 10.1002/cmdc.201400007  0.48
2013 Liu JZ, Zhang SE, Nie F, Yang Y, Tang YB, Yin W, Tian JY, Ye F, Xiao Z. Discovery of novel PTP1B inhibitors via pharmacophore-oriented scaffold hopping from Ertiprotafib. Bioorganic & Medicinal Chemistry Letters. 23: 6217-22. PMID 24148325 DOI: 10.1016/j.bmcl.2013.10.002  0.48
2013 Hansel RA, Xiao Z, Hu Y, Green O, Yang D, Harold Li H. The role of activator concentration and precipitate formation on optical and dosimetric properties of KCl:Eu(2+) storage phosphor detectors. Medical Physics. 40: 092104. PMID 24007173 DOI: 10.1118/1.4817522  0.64
2013 Wei S, Tang YB, Hua H, Ohkoshi E, Goto M, Wang LT, Lee KH, Xiao Z. Discovery of novel andrographolide derivatives as cytotoxic agents. Bioorganic & Medicinal Chemistry Letters. 23: 4056-60. PMID 23768904 DOI: 10.1016/j.bmcl.2013.05.061  0.88
2013 Li HH, Xiao Z, Hansel R, Knutson N, Yang D. Performance of KCl:Eu2+ storage phosphor dosimeters for low-dose measurements. Physics in Medicine and Biology. 58: 4357-66. PMID 23735856 DOI: 10.1088/0031-9155/58/12/4357  0.64
2013 Tang YB, Lu D, Chen Z, Hu C, Yang Y, Tian JY, Ye F, Wu L, Zhang ZY, Xiao Z. Design, synthesis and insulin-sensitising effects of novel PTP1B inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 2313-8. PMID 23499238 DOI: 10.1016/j.bmcl.2013.02.073  0.48
2013 Xiao Z, Hansel R, Chen H, Du D, Yang D, Li HH. Temporal signal stability of KCl:Eu(2+) storage phosphor dosimeters. Medical Physics. 40: 021721. PMID 23387744 DOI: 10.1118/1.4789482  0.64
2012 Li J, Hua HM, Tang YB, Zhang S, Ohkoshi E, Lee KH, Xiao Zy. Synthesis and evaluation of novel podophyllotoxin analogs. Bioorganic & Medicinal Chemistry Letters. 22: 4293-5. PMID 22658864 DOI: 10.1016/j.bmcl.2012.05.033  0.88
2012 Xu K, Xiao Z, Tang YB, Huang L, Chen CH, Ohkoshi E, Lee KH. Design and synthesis of naphthoquinone derivatives as antiproliferative agents and 20S proteasome inhibitors. Bioorganic & Medicinal Chemistry Letters. 22: 2772-4. PMID 22437113 DOI: 10.1016/j.bmcl.2012.02.086  0.88
2012 Chen MC, Pan SL, Shi Q, Xiao Z, Lee KH, Li TK, Teng CM. QS-ZYX-1-61 induces apoptosis through topoisomerase II in human non-small-cell lung cancer A549 cells. Cancer Science. 103: 80-7. PMID 21920000 DOI: 10.1111/j.1349-7006.2011.02103.x  0.88
2011 Wang J, Xiao Z. Research on key technique of microscopy three-dimensional image reconstruction based on piezoelectric ceramics Proceedings of Spie - the International Society For Optical Engineering. 8202. DOI: 10.1117/12.907209  0.32
2005 Lai YY, Huang LJ, Lee KH, Xiao Z, Bastow KF, Yamori T, Kuo SC. Synthesis and biological relationships of 3',6-substituted 2-phenyl-4-quinolone-3-carboxylic acid derivatives as antimitotic agents. Bioorganic & Medicinal Chemistry. 13: 265-75. PMID 15582470 DOI: 10.1016/j.bmc.2004.09.041  0.88
2005 Xiao ZX. Optics system design of eyeground television Guangxue Jishu/Optical Technique. 31: 170-172.  0.32
2004 Xiao Z, Bastow KF, Vance JR, Sidwell RS, Wang HK, Chen MS, Shi Q, Lee KH. Antitumor agents. 234. Design, synthesis, and biological evaluation of novel 4β-[(4″-benzamido)-amino]-4′-O-demethyl- epipodophyllotoxin derivatives Journal of Medicinal Chemistry. 47: 5140-5148. PMID 15456257 DOI: 10.1021/jm030609l  0.88
2004 Xiao Z, Varma S, Xiao YD, Tropsha A. Modeling of p38 mitogen-activated protein kinase inhibitors using the Catalyst HypoGen and k-nearest neighbor QSAR methods. Journal of Molecular Graphics & Modelling. 23: 129-38. PMID 15363455 DOI: 10.1016/j.jmgm.2004.05.001  0.88
2004 Zhu XK, Guan J, Xiao Z, Cosentino LM, Lee KH. Anti-AIDS agents. Part 61: Anti-HIV activity of new podophyllotoxin derivatives. Bioorganic & Medicinal Chemistry. 12: 4267-73. PMID 15246103 DOI: 10.1016/j.bmc.2004.04.048  0.88
2004 Xiao Z, Vance JR, Bastow KF, Brossi A, Wang HK, Lee KH. Antitumor agents. Part 235: Novel 4′-ester etoposide analogues as potent DNA topoisomerase II inhibitors with improved therapeutic potential Bioorganic and Medicinal Chemistry. 12: 3363-3369. PMID 15158805 DOI: 10.1016/j.bmc.2004.03.056  0.88
2004 Xiao Z, Bastow KF, Vance JR, Lee KH. Antitumor agents. Part 227: Studies on novel 4′-O-demethyl- epipodophyllotoxins as antitumor agents targeting topoisomerase II Bioorganic and Medicinal Chemistry. 12: 3339-3344. PMID 15158802 DOI: 10.1016/j.bmc.2004.03.067  0.88
2004 Han S, Xiao Z, Bastow KF, Lee KH. Antitumor agents. Part 230: C4'-esters of GL-331 as cytotoxic agents and DNA topoisomerase II inhibitors. Bioorganic & Medicinal Chemistry Letters. 14: 2979-82. PMID 15125972 DOI: 10.1016/j.bmcl.2004.02.102  0.88
2004 Xiao Z, Han S, Bastow KF, Lee KH. Antitumor agents. Part 232: Synthesis of cyclosulfite podophyllotoxin analogues as novel prototype antitumor agents. Bioorganic & Medicinal Chemistry Letters. 14: 1581-4. PMID 15006408 DOI: 10.1016/j.bmcl.2003.12.096  0.88
2003 Ohtsu H, Itokawa H, Xiao Z, Su CY, Shih CC, Chiang T, Chang E, Lee Y, Chiu SY, Chang C, Lee KH. Antitumor agents 222. Synthesis and anti-androgen activity of new diarylheptanoids. Bioorganic & Medicinal Chemistry. 11: 5083-90. PMID 14604672  0.88
2003 Golbraikh A, Shen M, Xiao Z, Xiao YD, Lee KH, Tropsha A. Rational selection of training and test sets for the development of validated QSAR models. Journal of Computer-Aided Molecular Design. 17: 241-53. PMID 13677490 DOI: 10.1023/A:1025386326946  0.88
2002 Ohtsu H, Xiao Z, Ishida J, Nagai M, Wang HK, Itokawa H, Su CY, Shih C, Chiang T, Chang E, Lee Y, Tsai MY, Chang C, Lee KH. Antitumor agents. 217. Curcumin analogues as novel androgen receptor antagonists with potential as anti-prostate cancer agents. Journal of Medicinal Chemistry. 45: 5037-42. PMID 12408714  0.88
2002 Xiao Z, Xiao YD, Feng J, Golbraikh A, Tropsha A, Lee KH. Antitumor agents. 213. Modeling of epipodophyllotoxin derivatives using variable selection k nearest neighbor QSAR method. Journal of Medicinal Chemistry. 45: 2294-309. PMID 12014968 DOI: 10.1021/jm0105427  0.88
1997 Yi F, Xiao Z. Evolution of gravity waves through resonant and nonresonant interactions in a dissipative atmosphere Journal of Atmospheric and Solar-Terrestrial Physics. 59: 305-317.  0.36
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