Erin Heinzen, Ph.D. - Publications

Affiliations: 
2004 University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Pharmacy, Pharmacology

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Helbig I, Heinzen EL, Mefford HC. Primer Part 1-The building blocks of epilepsy genetics. Epilepsia. PMID 27226047 DOI: 10.1111/epi.13381  1
2016 Griffin NG, Wang Y, Hulette CM, Halvorsen M, Cronin KD, Walley NM, Haglund MM, Radtke RA, Skene JH, Sinha SR, Heinzen EL. Differential gene expression in dentate granule cells in mesial temporal lobe epilepsy with and without hippocampal sclerosis. Epilepsia. PMID 26799155 DOI: 10.1111/epi.13305  1
2015 Heinzen EL, Neale BM, Traynelis SF, Allen AS, Goldstein DB. The Genetics of Neuropsychiatric Diseases: Looking In and Beyond the Exome. Annual Review of Neuroscience. 38: 47-68. PMID 25840007 DOI: 10.1146/annurev-neuro-071714-034136  1
2015 Li M, Jazayeri D, Corry B, McSweeney KM, Heinzen EL, Goldstein DB, Petrou S. A functional correlate of severity in alternating hemiplegia of childhood. Neurobiology of Disease. 77: 88-93. PMID 25681536 DOI: 10.1016/j.nbd.2015.02.002  1
2014 Jiang Y, Satten GA, Han Y, Epstein MP, Heinzen EL, Goldstein DB, Allen AS. Utilizing population controls in rare-variant case-parent association tests. American Journal of Human Genetics. 94: 845-53. PMID 24836453 DOI: 10.1016/j.ajhg.2014.04.014  1
2014 Heinzen EL, Arzimanoglou A, Brashear A, Clapcote SJ, Gurrieri F, Goldstein DB, Jóhannesson SH, Mikati MA, Neville B, Nicole S, Ozelius LJ, Poulsen H, Schyns T, Sweadner KJ, van den Maagdenberg A, et al. Distinct neurological disorders with ATP1A3 mutations. The Lancet. Neurology. 13: 503-14. PMID 24739246 DOI: 10.1016/S1474-4422(14)70011-0  1
2014 Sánchez Fernández I, Abend NS, Agadi S, An S, Arya R, Carpenter JL, Chapman KE, Gaillard WD, Glauser TA, Goldstein DB, Goldstein JL, Goodkin HP, Hahn CD, Heinzen EL, Mikati MA, et al. Gaps and opportunities in refractory status epilepticus research in children: a multi-center approach by the Pediatric Status Epilepticus Research Group (pSERG). Seizure. 23: 87-97. PMID 24183923 DOI: 10.1016/j.seizure.2013.10.004  1
2013 Poduri A, Heinzen EL, Chitsazzadeh V, Lasorsa FM, Elhosary PC, LaCoursiere CM, Martin E, Yuskaitis CJ, Hill RS, Atabay KD, Barry B, Partlow JN, Bashiri FA, Zeidan RM, Elmalik SA, et al. SLC25A22 is a novel gene for migrating partial seizures in infancy. Annals of Neurology. 74: 873-82. PMID 24596948 DOI: 10.1002/ana.23998  1
2013 Petrovski S, Wang Q, Heinzen EL, Allen AS, Goldstein DB. Genic intolerance to functional variation and the interpretation of personal genomes. Plos Genetics. 9: e1003709. PMID 23990802 DOI: 10.1371/journal.pgen.1003709  1
2013 Allen AS, Berkovic SF, Cossette P, Delanty N, Dlugos D, Eichler EE, Epstein MP, Glauser T, Goldstein DB, Han Y, Heinzen EL, Hitomi Y, Howell KB, et al. De novo mutations in epileptic encephalopathies. Nature. 501: 217-21. PMID 23934111 DOI: 10.1038/nature12439  1
2013 Hitomi Y, Heinzen EL, Donatello S, Dahl HH, Damiano JA, McMahon JM, Berkovic SF, Scheffer IE, Legros B, Rai M, Weckhuysen S, Suls A, De Jonghe P, Pandolfo M, Goldstein DB, et al. Mutations in TNK2 in severe autosomal recessive infantile onset epilepsy. Annals of Neurology. 74: 496-501. PMID 23686771 DOI: 10.1002/ana.23934  1
2012 Manzini MC, Tambunan DE, Hill RS, Yu TW, Maynard TM, Heinzen EL, Shianna KV, Stevens CR, Partlow JN, Barry BJ, Rodriguez J, Gupta VA, Al-Qudah AK, Eyaid WM, Friedman JM, et al. Exome sequencing and functional validation in zebrafish identify GTDC2 mutations as a cause of Walker-Warburg syndrome. American Journal of Human Genetics. 91: 541-7. PMID 22958903 DOI: 10.1016/j.ajhg.2012.07.009  1
2012 Zhu M, Need AC, Han Y, Ge D, Maia JM, Zhu Q, Heinzen EL, Cirulli ET, Pelak K, He M, Ruzzo EK, Gumbs C, Singh A, Feng S, Shianna KV, et al. Using ERDS to infer copy-number variants in high-coverage genomes. American Journal of Human Genetics. 91: 408-21. PMID 22939633 DOI: 10.1016/j.ajhg.2012.07.004  1
2012 Zhu Q, Ge D, Heinzen EL, Dickson SP, Urban TJ, Zhu M, Maia JM, He M, Zhao Q, Shianna KV, Goldstein DB. Prioritizing genetic variants for causality on the basis of preferential linkage disequilibrium. American Journal of Human Genetics. 91: 422-34. PMID 22939045 DOI: 10.1016/j.ajhg.2012.07.010  1
2012 Need AC, McEvoy JP, Gennarelli M, Heinzen EL, Ge D, Maia JM, Shianna KV, He M, Cirulli ET, Gumbs CE, Zhao Q, Campbell CR, Hong L, Rosenquist P, Putkonen A, et al. Exome sequencing followed by large-scale genotyping suggests a limited role for moderately rare risk factors of strong effect in schizophrenia. American Journal of Human Genetics. 91: 303-12. PMID 22863191 DOI: 10.1016/j.ajhg.2012.06.018  1
2012 Heinzen EL, Depondt C, Cavalleri GL, Ruzzo EK, Walley NM, Need AC, Ge D, He M, Cirulli ET, Zhao Q, Cronin KD, Gumbs CE, Campbell CR, Hong LK, Maia JM, et al. Exome sequencing followed by large-scale genotyping fails to identify single rare variants of large effect in idiopathic generalized epilepsy. American Journal of Human Genetics. 91: 293-302. PMID 22863189 DOI: 10.1016/j.ajhg.2012.06.016  1
2012 Heinzen EL, Swoboda KJ, Hitomi Y, Gurrieri F, Nicole S, de Vries B, Tiziano FD, Fontaine B, Walley NM, Heavin S, Panagiotakaki E, Fiori S, et al. De novo mutations in ATP1A3 cause alternating hemiplegia of childhood. Nature Genetics. 44: 1030-4. PMID 22842232 DOI: 10.1038/ng.2358  1
2012 Poduri A, Evrony GD, Cai X, Elhosary PC, Beroukhim R, Lehtinen MK, Hills LB, Heinzen EL, Hill A, Hill RS, Barry BJ, Bourgeois BF, Riviello JJ, Barkovich AJ, Black PM, et al. Somatic activation of AKT3 causes hemispheric developmental brain malformations. Neuron. 74: 41-8. PMID 22500628 DOI: 10.1016/j.neuron.2012.03.010  1
2012 McCormack M, Urban TJ, Shianna KV, Walley N, Pandolfo M, Depondt C, Chaila E, O'Conner GD, Kasperavičiūtė D, Radtke RA, Heinzen EL, Sisodiya SM, Delanty N, Cavalleri GL. Genome-wide mapping for clinically relevant predictors of lamotrigine- and phenytoin-induced hypersensitivity reactions. Pharmacogenomics. 13: 399-405. PMID 22379998 DOI: 10.2217/pgs.11.165  1
2011 Cirulli ET, Heinzen EL, Dietrich FS, Shianna KV, Singh A, Maia JM, Goedert JJ, Goldstein DB. A whole-genome analysis of premature termination codons. Genomics. 98: 337-42. PMID 21803148 DOI: 10.1016/j.ygeno.2011.07.001  1
2011 Catarino CB, Kasperavičiūtė D, Thom M, Cavalleri GL, Martinian L, Heinzen EL, Dorn T, Grunwald T, Chaila E, Depondt C, Krämer G, Delanty N, Goldstein DB, Sisodiya SM. Genomic microdeletions associated with epilepsy: not a contraindication to resective surgery. Epilepsia. 52: 1388-92. PMID 21635232 DOI: 10.1111/j.1528-1167.2011.03087.x  1
2011 Ge D, Ruzzo EK, Shianna KV, He M, Pelak K, Heinzen EL, Need AC, Cirulli ET, Maia JM, Dickson SP, Zhu M, Singh A, Allen AS, Goldstein DB. SVA: software for annotating and visualizing sequenced human genomes. Bioinformatics (Oxford, England). 27: 1998-2000. PMID 21624899 DOI: 10.1093/bioinformatics/btr317  1
2011 Zhu Q, Ge D, Maia JM, Zhu M, Petrovski S, Dickson SP, Heinzen EL, Shianna KV, Goldstein DB. A genome-wide comparison of the functional properties of rare and common genetic variants in humans. American Journal of Human Genetics. 88: 458-68. PMID 21457907 DOI: 10.1016/j.ajhg.2011.03.008  1
2011 McCormack M, Alfirevic A, Bourgeois S, Farrell JJ, KasperavičiÅ«tÄ— D, Carrington M, Sills GJ, Marson T, Jia X, de Bakker PI, Chinthapalli K, Molokhia M, Johnson MR, O'Connor GD, Chaila E, ... ... Heinzen EL, et al. HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans. The New England Journal of Medicine. 364: 1134-43. PMID 21428769 DOI: 10.1056/NEJMoa1013297  1
2010 Pelak K, Shianna KV, Ge D, Maia JM, Zhu M, Smith JP, Cirulli ET, Fellay J, Dickson SP, Gumbs CE, Heinzen EL, Need AC, Ruzzo EK, Singh A, Campbell CR, et al. The characterization of twenty sequenced human genomes. Plos Genetics. 6: e1001111. PMID 20838461 DOI: 10.1371/journal.pgen.1001111  1
2010 Cirulli ET, Singh A, Shianna KV, Ge D, Smith JP, Maia JM, Heinzen EL, Goedert JJ, Goldstein DB. Screening the human exome: a comparison of whole genome and whole transcriptome sequencing. Genome Biology. 11: R57. PMID 20598109 DOI: 10.1186/gb-2010-11-5-r57  1
2010 Kasperavici?te D, Catarino CB, Heinzen EL, Depondt C, Cavalleri GL, Caboclo LO, Tate SK, Jamnadas-Khoda J, Chinthapalli K, Clayton LM, Shianna KV, Radtke RA, Mikati MA, Gallentine WB, Husain AM, et al. Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study. Brain : a Journal of Neurology. 133: 2136-47. PMID 20522523 DOI: 10.1093/brain/awq130  1
2010 Beskow LM, Linney KN, Radtke RA, Heinzen EL, Goldstein DB. Ethical challenges in genotype-driven research recruitment. Genome Research. 20: 705-9. PMID 20418491 DOI: 10.1101/gr.104455.109  1
2010 Heinzen EL, Radtke RA, Urban TJ, Cavalleri GL, Depondt C, Need AC, Walley NM, Nicoletti P, Ge D, Catarino CB, Duncan JS, Kasperavici?te D, Tate SK, Caboclo LO, Sander JW, et al. Rare deletions at 16p13.11 predispose to a diverse spectrum of sporadic epilepsy syndromes. American Journal of Human Genetics. 86: 707-18. PMID 20398883 DOI: 10.1016/j.ajhg.2010.03.018  1
2010 Rotger M, Dang KK, Fellay J, Heinzen EL, Feng S, Descombes P, Shianna KV, Ge D, Günthard HF, Goldstein DB, Telenti A. Genome-wide mRNA expression correlates of viral control in CD4+ T-cells from HIV-1-infected individuals. Plos Pathogens. 6: e1000781. PMID 20195503 DOI: 10.1371/journal.ppat.1000781  1
2010 Heinzen EL, Need AC, Hayden KM, Chiba-Falek O, Roses AD, Strittmatter WJ, Burke JR, Hulette CM, Welsh-Bohmer KA, Goldstein DB. Genome-wide scan of copy number variation in late-onset Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 19: 69-77. PMID 20061627 DOI: 10.3233/JAD-2010-1212  1
2009 Need AC, Attix DK, McEvoy JM, Cirulli ET, Linney KL, Hunt P, Ge D, Heinzen EL, Maia JM, Shianna KV, Weale ME, Cherkas LF, Clement G, Spector TD, Gibson G, et al. A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB. Human Molecular Genetics. 18: 4650-61. PMID 19734545 DOI: 10.1093/hmg/ddp413  1
2009 Ge D, Fellay J, Thompson AJ, Simon JS, Shianna KV, Urban TJ, Heinzen EL, Qiu P, Bertelsen AH, Muir AJ, Sulkowski M, McHutchison JG, Goldstein DB. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature. 461: 399-401. PMID 19684573 DOI: 10.1038/nature08309  1
2009 Need AC, Ge D, Weale ME, Maia J, Feng S, Heinzen EL, Shianna KV, Yoon W, KasperaviciÅ«te D, Gennarelli M, Strittmatter WJ, Bonvicini C, Rossi G, Jayathilake K, Cola PA, et al. A genome-wide investigation of SNPs and CNVs in schizophrenia. Plos Genetics. 5: e1000373. PMID 19197363 DOI: 10.1371/journal.pgen.1000373  1
2008 Heinzen EL, Ge D, Cronin KD, Maia JM, Shianna KV, Gabriel WN, Welsh-Bohmer KA, Hulette CM, Denny TN, Goldstein DB. Tissue-specific genetic control of splicing: implications for the study of complex traits. Plos Biology. 6: e1. PMID 19222302 DOI: 10.1371/journal.pbio.1000001  1
2007 Ervin JF, Heinzen EL, Cronin KD, Goldstein D, Szymanski MH, Burke JR, Welsh-Bohmer KA, Hulette CM. Postmortem delay has minimal effect on brain RNA integrity. Journal of Neuropathology and Experimental Neurology. 66: 1093-9. PMID 18090918 DOI: 10.1097/nen.0b013e31815c196a  1
2007 Heinzen EL, Yoon W, Tate SK, Sen A, Wood NW, Sisodiya SM, Goldstein DB. Nova2 interacts with a cis-acting polymorphism to influence the proportions of drug-responsive splice variants of SCN1A. American Journal of Human Genetics. 80: 876-83. PMID 17436242 DOI: 10.1086/516650  1
2007 Heinzen EL, Yoon W, Weale ME, Sen A, Wood NW, Burke JR, Welsh-Bohmer KA, Hulette CM, Sisodiya SM, Goldstein DB. Alternative ion channel splicing in mesial temporal lobe epilepsy and Alzheimer's disease. Genome Biology. 8: R32. PMID 17343748 DOI: 10.1186/gb-2007-8-3-r32  1
2005 Heinzen EL, Booth RG, Pollack GM. Neuronal nitric oxide modulates morphine antinociceptive tolerance by enhancing constitutive activity of the mu-opioid receptor. Biochemical Pharmacology. 69: 679-88. PMID 15670586 DOI: 10.1016/j.bcp.2004.11.004  1
2005 Naderer OJ, Dupuis RE, Heinzen EL, Wiwattanawongsa K, Johnson MW, Smith PC. The influence of norfloxacin and metronidazole on the disposition of mycophenolate mofetil. Journal of Clinical Pharmacology. 45: 219-26. PMID 15647415 DOI: 10.1177/0091270004271555  1
2004 Heinzen EL, Pollack GM. Pharmacodynamics of morphine-induced neuronal nitric oxide production and antinociceptive tolerance development. Brain Research. 1023: 175-84. PMID 15374743 DOI: 10.1016/j.brainres.2004.07.015  1
2004 Heinzen EL, Pollack GM. The development of morphine antinociceptive tolerance in nitric oxide synthase-deficient mice. Biochemical Pharmacology. 67: 735-41. PMID 14757173 DOI: 10.1016/j.bcp.2003.08.046  1
2003 Heinzen EL, Pollack GM. Pharmacokinetics and pharmacodynamics of L-arginine in rats: a model of stimulated neuronal nitric oxide synthesis. Brain Research. 989: 67-75. PMID 14519513 DOI: 10.1016/S0006-8993(03)03370-5  1
2002 Heinzen EL, Pollack GM. Use of an electrochemical nitric oxide sensor to detect neuronal nitric oxide production in conscious, unrestrained rats. Journal of Pharmacological and Toxicological Methods. 48: 139-46. PMID 14986862 DOI: 10.1016/S1056-8719(03)00043-1  1
2001 Wiwattanawongsa K, Heinzen EL, Kemp DC, Dupuis RE, Smith PC. Determination of mycophenolic acid and its phenol glucuronide metabolite in human plasma and urine by high-performance liquid chromatography Journal of Chromatography B: Biomedical Sciences and Applications. 763: 35-45. PMID 11710581 DOI: 10.1016/S0378-4347(01)00354-1  1
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