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Eric S. Dawson, Ph.D. - Publications

Affiliations: 
2001 Vanderbilt University, Nashville, TN 
Area:
Pharmacology, Biochemistry, Molecular Biology
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19/55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Li J, Smith JA, Dawson ES, Fu A, Nickels M, Schulte ML, Manning HC. An Optimized Translocator Protein Ligand for Optical Molecular Imaging and Screening. Bioconjugate Chemistry. PMID 28156095 DOI: 10.1021/Acs.Bioconjchem.6B00711  0.335
2015 Schulte ML, Dawson ES, Saleh SA, Cuthbertson ML, Manning HC. 2-Substituted Nγ-glutamylanilides as novel probes of ASCT2 with improved potency. Bioorganic & Medicinal Chemistry Letters. 25: 113-6. PMID 25435145 DOI: 10.1016/J.Bmcl.2014.10.098  0.392
2013 Turlington M, Chun A, Tomar S, Eggler A, Grum-Tokars V, Jacobs J, Daniels JS, Dawson E, Saldanha A, Chase P, Baez-Santos YM, Lindsley CW, Hodder P, Mesecar AD, Stauffer SR. Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding. Bioorganic & Medicinal Chemistry Letters. 23: 6172-7. PMID 24080461 DOI: 10.1016/J.Bmcl.2013.08.112  0.346
2013 Jacobs J, Grum-Tokars V, Zhou Y, Turlington M, Saldanha SA, Chase P, Eggler A, Dawson ES, Baez-Santos YM, Tomar S, Mielech AM, Baker SC, Lindsley CW, Hodder P, Mesecar A, et al. Discovery, synthesis, and structure-based optimization of a series of N-(tert-butyl)-2-(N-arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease. Journal of Medicinal Chemistry. 56: 534-46. PMID 23231439 DOI: 10.1021/Jm301580N  0.322
2012 Rodriguez AL, Zhou Y, Williams R, Weaver CD, Vinson PN, Dawson ES, Steckler T, Lavreysen H, Mackie C, Bartolomé JM, Macdonald GJ, Daniels JS, Niswender CM, Jones CK, Conn PJ, et al. Discovery and SAR of a novel series of non-MPEP site mGluâ‚… PAMs based on an aryl glycine sulfonamide scaffold. Bioorganic & Medicinal Chemistry Letters. 22: 7388-92. PMID 23142615 DOI: 10.1016/J.Bmcl.2012.10.068  0.349
2012 Mueller R, Dawson ES, Niswender CM, Butkiewicz M, Hopkins CR, Weaver CD, Lindsley CW, Conn PJ, Meiler J. Iterative experimental and virtual high-throughput screening identifies metabotropic glutamate receptor subtype 4 positive allosteric modulators. Journal of Molecular Modeling. 18: 4437-46. PMID 22592386 DOI: 10.1007/S00894-012-1441-0  0.36
2012 Mueller R, Dawson ES, Meiler J, Rodriguez AL, Chauder BA, Bates BS, Felts AS, Lamb JP, Menon UN, Jadhav SB, Kane AS, Jones CK, Gregory KJ, Niswender CM, Conn PJ, et al. Discovery of 2-(2-benzoxazoyl amino)-4-aryl-5-cyanopyrimidine as negative allosteric modulators (NAMs) of metabotropic glutamate receptor 5 (mGluâ‚…): from an artificial neural network virtual screen to an in vivo tool compound. Chemmedchem. 7: 406-14. PMID 22267125 DOI: 10.1002/Cmdc.201100510  0.358
2012 Zdravkovic I, Henry KL, Dawson ES, Noskov SY. Molecular Dynamics Approach to Determine the Importance of an Asparagine Residue on Chloride-Dependence in the Human Serotonin Transporter Biophysical Journal. 102: 523a. DOI: 10.1016/J.Bpj.2011.11.2859  0.327
2011 Bhave G, Chauder BA, Liu W, Dawson ES, Kadakia R, Nguyen TT, Lewis LM, Meiler J, Weaver CD, Satlin LM, Lindsley CW, Denton JS. Development of a selective small-molecule inhibitor of Kir1.1, the renal outer medullary potassium channel. Molecular Pharmacology. 79: 42-50. PMID 20926757 DOI: 10.1124/Mol.110.066928  0.342
2010 Lebois EP, Bridges TM, Lewis LM, Dawson ES, Kane AS, Xiang Z, Jadhav SB, Yin H, Kennedy JP, Meiler J, Niswender CM, Jones CK, Conn PJ, Weaver CD, Lindsley CW. Discovery and characterization of novel subtype-selective allosteric agonists for the investigation of M(1) receptor function in the central nervous system. Acs Chemical Neuroscience. 1: 104-121. PMID 21961051 DOI: 10.1021/Cn900003H  0.344
2010 Mueller R, Rodriguez AL, Dawson ES, Butkiewicz M, Nguyen TT, Oleszkiewicz S, Bleckmann A, Weaver CD, Lindsley CW, Conn PJ, Meiler J. Identification of Metabotropic Glutamate Receptor Subtype 5 Potentiators Using Virtual High-Throughput Screening. Acs Chemical Neuroscience. 1: 288-305. PMID 20414370 DOI: 10.1021/Cn9000389  0.363
2010 Denton JS, Chauder BA, Kadakia R, Dawson ES, Lindsley C, Weaver CD, Bhave G. Chemical Synthesis of a Highly Selective Probe of the Renal Outer Medullary Potassium Channel (ROMK) Biophysical Journal. 98: 755a. DOI: 10.1016/J.Bpj.2009.12.4144  0.377
2009 Kaufmann KW, Dawson ES, Henry LK, Field JR, Blakely RD, Meiler J. Structural determinants of species-selective substrate recognition in human and Drosophila serotonin transporters revealed through computational docking studies. Proteins. 74: 630-42. PMID 18704946 DOI: 10.1002/Prot.22178  0.359
2008 Hanson SM, Dawson ES, Francis DJ, Van Eps N, Klug CS, Hubbell WL, Meiler J, Gurevich VV. A model for the solution structure of the rod arrestin tetramer. Structure (London, England : 1993). 16: 924-34. PMID 18547524 DOI: 10.1016/J.Str.2008.03.006  0.302
2007 Rigsby RE, Brown DW, Dawson E, Lybrand TP, Armstrong RN. A model for glutathione binding and activation in the fosfomycin resistance protein, FosA. Archives of Biochemistry and Biophysics. 464: 277-83. PMID 17537395 DOI: 10.1016/J.Abb.2007.04.035  0.312
2006 Hadac EM, Dawson ES, Darrow JW, Sugg EE, Lybrand TP, Miller LJ. Novel benzodiazepine photoaffinity probe stereoselectively labels a site deep within the membrane-spanning domain of the cholecystokinin receptor. Journal of Medicinal Chemistry. 49: 850-63. PMID 16451051 DOI: 10.1021/Jm049072H  0.42
2004 Harikumar KG, Pinon DI, Wessels WS, Dawson ES, Lybrand TP, Prendergast FG, Miller LJ. Measurement of intermolecular distances for the natural agonist Peptide docked at the cholecystokinin receptor expressed in situ using fluorescence resonance energy transfer. Molecular Pharmacology. 65: 28-35. PMID 14722234 DOI: 10.1124/Mol.65.1.28  0.375
2002 Dawson ES, Henne RM, Miller LJ, Lybrand TP. Moleular models for cholecystokinin-A receptor. Pharmacology & Toxicology. 91: 290-6. PMID 12688371 DOI: 10.1034/J.1600-0773.2002.910605.X  0.333
2001 Dawson ES, Wells JN. Determination of amino acid residues that are accessible from the ligand binding crevice in the seventh transmembrane-spanning region of the human A(1) adenosine receptor. Molecular Pharmacology. 59: 1187-95. PMID 11306703 DOI: 10.1124/Mol.59.5.1187  0.527
Low-probability matches (unlikely to be authored by this person)
2011 Wang HR, Wu M, Yu H, Long S, Stevens A, Engers DW, Sackin H, Daniels JS, Dawson ES, Hopkins CR, Lindsley CW, Li M, McManus OB. Selective inhibition of the K(ir)2 family of inward rectifier potassium channels by a small molecule probe: the discovery, SAR, and pharmacological characterization of ML133. Acs Chemical Biology. 6: 845-56. PMID 21615117 DOI: 10.1021/Cb200146A  0.278
2011 Henry LK, Iwamoto H, Field JR, Kaufmann K, Dawson ES, Jacobs MT, Adams C, Felts B, Zdravkovic I, Armstrong V, Combs S, Solis E, Rudnick G, Noskov SY, DeFelice LJ, et al. A conserved asparagine residue in transmembrane segment 1 (TM1) of serotonin transporter dictates chloride-coupled neurotransmitter transport. The Journal of Biological Chemistry. 286: 30823-36. PMID 21730057 DOI: 10.1074/Jbc.M111.250308  0.271
2012 Theriault JR, Felts AS, Bates BS, Perez JR, Palmer M, Gilbert SR, Dawson ES, Engers JL, Lindsley CW, Emmitte KA. Discovery of a new molecular probe ML228: an activator of the hypoxia inducible factor (HIF) pathway. Bioorganic & Medicinal Chemistry Letters. 22: 76-81. PMID 22172704 DOI: 10.1016/J.Bmcl.2011.11.077  0.268
2009 Lebois EP, Bridges TM, Dawson ES, Kennedy JP, Xiang Z, Jadhav SB, Yin H, Meiler J, Jones CK, Conn PJ, Weaver CD, Lindsley CW. P2-256: Towards the treatment of Alzheimer's disease: Discovery and development of novel subtype-specific M1 allosteric agonists Alzheimer's & Dementia. 5: P335-P335. DOI: 10.1016/J.Jalz.2009.04.570  0.266
2011 Xiang Z, Thompson AD, Brogan JT, Schulte ML, Melancon BJ, Mi D, Lewis LM, Zou B, Yang L, Morrison R, Santomango T, Byers F, Brewer K, Aldrich JS, Yu H, ... Dawson ES, et al. The Discovery and Characterization of ML218: A Novel, Centrally Active T-Type Calcium Channel Inhibitor with Robust Effects in STN Neurons and in a Rodent Model of Parkinson's Disease. Acs Chemical Neuroscience. 2: 730-742. PMID 22368764 DOI: 10.1021/Cn200090Z  0.262
2010 Bhave G, Chauder BA, Kadakia R, Dawson ES, Lindsley CW, Weaver CD, Denton JS. 55: Rational Synthesis of a Selective Renal Outer Medullary Potassium Channel (ROMK) Antagonist American Journal of Kidney Diseases. 55: B45. DOI: 10.1053/J.Ajkd.2010.02.062  0.261
2014 de Souza A, Bittker JA, Lahr DL, Brudz S, Chatwin S, Oprea TI, Waller A, Yang JJ, Southall N, Guha R, Schürer SC, Vempati UD, Southern MR, Dawson ES, Clemons PA, et al. An Overview of the Challenges in Designing, Integrating, and Delivering BARD: A Public Chemical-Biology Resource and Query Portal for Multiple Organizations, Locations, and Disciplines. Journal of Biomolecular Screening. 19: 614-627. PMID 24441647 DOI: 10.1177/1087057113517139  0.252
2014 Hight MR, Cheung YY, Nickels ML, Dawson ES, Zhao P, Saleh S, Buck JR, Tang D, Washington MK, Coffey RJ, Manning HC. A peptide-based positron emission tomography probe for in vivo detection of caspase activity in apoptotic cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 2126-35. PMID 24573549 DOI: 10.1158/1078-0432.Ccr-13-2444  0.245
2010 Aldrich LN, Dawson ES, Lindsley CW. Evaluation of the biosynthetic proposal for the synthesis of marineosins A and B. Organic Letters. 12: 1048-51. PMID 20141121 DOI: 10.1021/Ol100034P  0.213
2010 Da Paula AC, Sousa M, Xu Z, Dawson ES, Boyd AC, Sheppard DN, Amaral MD. Folding and rescue of a cystic fibrosis transmembrane conductance regulator trafficking mutant identified using human-murine chimeric proteins. The Journal of Biological Chemistry. 285: 27033-44. PMID 20551307 DOI: 10.1074/Jbc.M110.120352  0.173
2006 Codreanu SG, Adams DG, Dawson ES, Wadzinski BE, Liebler DC. Inhibition of protein phosphatase 2A activity by selective electrophile alkylation damage. Biochemistry. 45: 10020-9. PMID 16906760 DOI: 10.1021/Bi060551N  0.161
2007 Scott-Ward TS, Cai Z, Dawson ES, Doherty A, Da Paula AC, Davidson H, Porteous DJ, Wainwright BJ, Amaral MD, Sheppard DN, Boyd AC. Chimeric constructs endow the human CFTR Cl- channel with the gating behavior of murine CFTR. Proceedings of the National Academy of Sciences of the United States of America. 104: 16365-70. PMID 17913891 DOI: 10.1073/Pnas.0701562104  0.132
2010 Lamb DC, Lei L, Zhao B, Yuan H, Jackson CJ, Warrilow AG, Skaug T, Dyson PJ, Dawson ES, Kelly SL, Hachey DL, Waterman MR. Streptomyces coelicolor A3(2) CYP102 protein, a novel fatty acid hydroxylase encoded as a heme domain without an N-terminal redox partner. Applied and Environmental Microbiology. 76: 1975-80. PMID 20097805 DOI: 10.1128/Aem.03000-09  0.123
1996 Atwood JL, Barbour LJ, Dawson ES, Junk PC, Kienzle J. X-ray Structure of the Water Soluble [Adeninium]-[p-Sulfonatocalix[4]arene] which Displays Cationic and Anionic Bilayers Supramolecular Chemistry. 7: 271-274. DOI: 10.1080/10610279608035197  0.113
1996 Atwood JL, Barbour LJ, Dawson ES, Junk PC, Kienzle J. X-ray structure of the water soluble [adeninium]-[p-sulfonatocalix[4]arene] which displays cationic and anionic bilayers Supramolecular Chemistry. 7: 271-274.  0.113
2014 Wu G, Dawson E, Duong A, Haw R, Stein L. ReactomeFIViz: a Cytoscape app for pathway and network-based data analysis. F1000research. 3: 146. PMID 25309732 DOI: 10.12688/f1000research.4431.2  0.104
2020 Chapman LM, Spies N, Pai P, Lim CS, Carroll A, Narzisi G, Watson CM, Proukakis C, Clarke WE, Nariai N, Dawson E, Jones G, Blankenberg D, Brueffer C, Xiao C, et al. A crowdsourced set of curated structural variants for the human genome. Plos Computational Biology. 16: e1007933. PMID 32559231 DOI: 10.1371/Journal.Pcbi.1007933  0.092
2022 Whitley P, LaRue L, Fernandez SA, Passik SD, Dawson E, Jackson RD. Analysis of Urine Drug Test Results From Substance Use Disorder Treatment Practices and Overdose Mortality Rates, 2013-2020. Jama Network Open. 5: e2215425. PMID 35657623 DOI: 10.1001/jamanetworkopen.2022.15425  0.073
2020 Stanton JD, Whitley P, LaRue L, Bundy WL, Dawson E, Huskey A. Fentanyl analog positivity among near-real-time urine drug test results in patients seeking health care. Drug and Alcohol Dependence. 217: 108264. PMID 32980789 DOI: 10.1016/j.drugalcdep.2020.108264  0.072
2023 Sadasivan H, Maric M, Dawson E, Iyer V, Israeli J, Narayanasamy S. Accelerating Minimap2 for Accurate Long Read Alignment on GPUs. Journal of Biotechnology and Biomedicine. 6: 13-23. PMID 36937168 DOI: 10.26502/jbb.2642-91280067  0.069
2020 Zhu GD, Dawson E, Huskey A, Gordon RJ, Del Tredici AL. Genetic Testing for Variants Identifies Patients at Risk of Prolonged Neuromuscular Blockade in Response to Succinylcholine. Pharmacogenomics and Personalized Medicine. 13: 405-414. PMID 33061533 DOI: 10.2147/PGPM.S263741  0.066
2020 LaRue L, Guevara MG, Whitley P, Dawson E, Twillman RK, Huskey A. The Cyclical and Evolving Nature of Methamphetamine Use: An Evaluation of Near Real-time Urine Drug Test Results. Journal of Addiction Medicine. PMID 33298749 DOI: 10.1097/ADM.0000000000000778  0.059
2023 Pytell JD, Whitley P, Passik SD, Bundy WL, Dawson E, Saloner B. Association of Patients' Direct Addition of Buprenorphine to Urine Drug Test Specimens With Clinical Factors in Opioid Use Disorder. Jama Psychiatry. PMID 36947029 DOI: 10.1001/jamapsychiatry.2023.0234  0.059
2021 Zhu GD, Whitley P, LaRue L, Adkins B, Dawson E, Huskey A, Capparelli EV, Del Tredici AL. Impact of genetic variation in CYP2C19, CYP2D6, and CYP3A4 on oxycodone and its metabolites in a large database of clinical urine drug tests. The Pharmacogenomics Journal. PMID 34480108 DOI: 10.1038/s41397-021-00253-5  0.058
2023 Saloner B, Whitley P, Dawson E, Passik S, Gordon AJ, Stein BD. Polydrug use among patients on methadone medication treatment: Evidence from urine drug testing to inform patient safety. Addiction (Abingdon, England). PMID 37158468 DOI: 10.1111/add.16180  0.053
2020 Wainwright JJ, Mikre M, Whitley P, Dawson E, Huskey A, Lukowiak A, Giroir BP. Analysis of Drug Test Results Before and After the US Declaration of a National Emergency Concerning the COVID-19 Outbreak. Jama. PMID 32945855 DOI: 10.1001/jama.2020.17694  0.053
2019 LaRue L, Twillman RK, Dawson E, Whitley P, Frasco MA, Huskey A, Guevara MG. Rate of Fentanyl Positivity Among Urine Drug Test Results Positive for Cocaine or Methamphetamine. Jama Network Open. 2: e192851. PMID 31026029 DOI: 10.1001/jamanetworkopen.2019.2851  0.051
2010 Lillis JV, Dawson ES, Chang R, White CR. Disseminated dermal Trichophyton rubrum infection - An expression of dermatophyte dimorphism? Journal of Cutaneous Pathology. 37: 1168-1169. PMID 19615031 DOI: 10.1111/j.1600-0560.2009.01355.x  0.046
2022 Guevara MG, LaRue L, Zacharoff KL, Whitley P, Dawson E, Passik SD. Definitive urine drug test findings in patients prescribed opioids for pain from a large national database. Journal of Opioid Management. 18: 361-375. PMID 36052933 DOI: 10.5055/jom.2022.0723  0.042
2021 Saloner B, Whitley P, LaRue L, Dawson E, Huskey A. Polysubstance Use Among Patients Treated With Buprenorphine From a National Urine Drug Test Database. Jama Network Open. 4: e2123019. PMID 34505888 DOI: 10.1001/jamanetworkopen.2021.23019  0.038
1998 Soto-Aguilar MC, deShazo RD, Dawson ES. APPROACH TO THE PATIENT WITH SUSPECTED LOCAL ANESTHETIC SENSITIVITY Immunology and Allergy Clinics of North America. 18: 851-865. DOI: 10.1016/S0889-8561(05)70044-8  0.035
2021 Olson KL, Whitley P, Velasco J, LaRue L, Dawson E, Huskey A. Seasonal and Regional Influences on Alcohol Consumption: An Analysis of Near-Real-Time Urine Drug Test Results in Those Seeking Health Care. Drug and Alcohol Dependence. 227: 108908. PMID 34352493 DOI: 10.1016/j.drugalcdep.2021.108908  0.033
2020 Twillman RK, Dawson E, LaRue L, Guevara MG, Whitley P, Huskey A. Evaluation of Trends of Near-Real-Time Urine Drug Test Results for Methamphetamine, Cocaine, Heroin, and Fentanyl. Jama Network Open. 3: e1918514. PMID 31899527 DOI: 10.1001/jamanetworkopen.2019.18514  0.031
1979 Dawson ES, Dunstan MRH. TRIALS FOR A PROTOTYPE ROLLED CONCRETE DAM Technology Review. 1: 647-660.  0.028
1998 Dawson E, Bernbeck J. The Surgical Treatment of Low Back Pain Physical Medicine and Rehabilitation Clinics of North America. 9: 489-495. DOI: 10.1016/S1047-9651(18)30270-5  0.016
1975 Symonds M, Dawson ES. The co therapist approach to group treatment with institutionalized early adolescent girls Groups: a Journal of Group Dynamics and Psychotherapy. 6: 27-36.  0.014
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