Year |
Citation |
Score |
2020 |
Lothstein L, Soberman J, Parke D, Gandhi J, Sweatman T, Seagroves T. Pivarubicin is more effective than doxorubicin against triple-negative breast cancer in vivo. Oncology Research. PMID 32430093 DOI: 10.3727/096504020X15898794315356 |
0.302 |
|
2013 |
Kim TK, Kleszczynski K, Janjetovic Z, Sweatman T, Lin Z, Li W, Reiter RJ, Fischer TW, Slominski AT. Metabolism of melatonin and biological activity of intermediates of melatoninergic pathway in human skin cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 2742-55. PMID 23620527 DOI: 10.1096/Fj.12-224691 |
0.322 |
|
2012 |
Slominski AT, Kim TK, Chen J, Nguyen MN, Li W, Yates CR, Sweatman T, Janjetovic Z, Tuckey RC. Cytochrome P450scc-dependent metabolism of 7-dehydrocholesterol in placenta and epidermal keratinocytes. The International Journal of Biochemistry & Cell Biology. 44: 2003-18. PMID 22877869 DOI: 10.1016/J.Biocel.2012.07.027 |
0.302 |
|
2011 |
Zmijewski MA, Li W, Chen J, Kim TK, Zjawiony JK, Sweatman TW, Miller DD, Slominski AT. Synthesis and photochemical transformation of 3β,21-dihydroxypregna-5,7-dien-20-one to novel secosteroids that show anti-melanoma activity. Steroids. 76: 193-203. PMID 21070794 DOI: 10.1016/J.Steroids.2010.10.009 |
0.317 |
|
2011 |
Estes AM, McAllen K, Parker MS, Sah R, Sweatman T, Park EA, Balasubramaniam A, Sallee FR, Walker MW, Parker SL. Maintenance of Y receptor dimers in epithelial cells depends on interaction with G-protein heterotrimers. Amino Acids. 40: 371-80. PMID 20577889 DOI: 10.1007/S00726-010-0642-Z |
0.305 |
|
2010 |
Li W, Chen J, Janjetovic Z, Kim TK, Sweatman T, Lu Y, Zjawiony J, Tuckey RC, Miller D, Slominski A. Chemical synthesis of 20S-hydroxyvitamin D3, which shows antiproliferative activity. Steroids. 75: 926-35. PMID 20542050 DOI: 10.1016/J.Steroids.2010.05.021 |
0.308 |
|
2009 |
Zmijewski MA, Sweatman TW, Slominski AT. The melatonin-producing system is fully functional in retinal pigment epithelium (ARPE-19). Molecular and Cellular Endocrinology. 307: 211-6. PMID 19409957 DOI: 10.1016/J.Mce.2009.04.010 |
0.302 |
|
2009 |
Slominski AT, Zmijewski MA, Semak I, Sweatman T, Janjetovic Z, Li W, Zjawiony JK, Tuckey RC. Sequential metabolism of 7-dehydrocholesterol to steroidal 5,7-dienes in adrenal glands and its biological implication in the skin. Plos One. 4: e4309. PMID 19190754 DOI: 10.1371/Journal.Pone.0004309 |
0.32 |
|
2009 |
Zmijewski MA, Li W, Zjawiony JK, Sweatman TW, Chen J, Miller DD, Slominski AT. Photo-conversion of two epimers (20R and 20S) of pregna-5,7-diene-3beta, 17alpha, 20-triol and their bioactivity in melanoma cells. Steroids. 74: 218-28. PMID 19028513 DOI: 10.1016/J.Steroids.2008.10.017 |
0.315 |
|
2008 |
Zmijewski MA, Li W, Zjawiony JK, Sweatman TW, Chen J, Miller DD, Slominski AT. Synthesis and photo-conversion of androsta- and pregna-5,7-dienes to vitamin D3-like derivatives. Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society For Photobiology. 7: 1570-6. PMID 19037511 DOI: 10.1039/B809005J |
0.316 |
|
2007 |
Hofmann PA, Israel M, Koseki Y, Laskin J, Gray J, Janik A, Sweatman TW, Lothstein L. N-Benzyladriamycin-14-valerate (AD 198): a non-cardiotoxic anthracycline that is cardioprotective through PKC-epsilon activation. The Journal of Pharmacology and Experimental Therapeutics. 323: 658-64. PMID 17693586 DOI: 10.1124/Jpet.107.126110 |
0.383 |
|
2007 |
He Y, Liu J, Grossman D, Durrant D, Sweatman T, Lothstein L, Epand RF, Epand RM, Lee RM. Phosphorylation of mitochondrial phospholipid scramblase 3 by protein kinase C-delta induces its activation and facilitates mitochondrial targeting of tBid. Journal of Cellular Biochemistry. 101: 1210-21. PMID 17226776 DOI: 10.1002/Jcb.21243 |
0.378 |
|
2007 |
Lothstein L, Savranskaya L, Sweatman TW. N-Benzyladriamycin-14-valerate (AD 198) cytotoxicty circumvents Bcr-Abl anti-apoptotic signaling in human leukemia cells and also potentiates imatinib cytotoxicity. Leukemia Research. 31: 1085-95. PMID 17187856 DOI: 10.1016/J.Leukres.2006.11.003 |
0.487 |
|
2006 |
Fischer TW, Zmijewski MA, Zbytek B, Sweatman TW, Slominski RM, Wortsman J, Slominski A. Oncostatic effects of the indole melatonin and expression of its cytosolic and nuclear receptors in cultured human melanoma cell lines International Journal of Oncology. 29: 665-672. PMID 16865283 DOI: 10.3892/Ijo.29.3.665 |
0.311 |
|
2006 |
Fischer TW, Sweatman TW, Semak I, Sayre RM, Wortsman J, Slominski A. Constitutive and UV-induced metabolism of melatonin in keratinocytes and cell-free systems. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1564-6. PMID 16793870 DOI: 10.1096/Fj.05-5227Fje |
0.314 |
|
2006 |
Lothstein L, Savranskaya L, Barrett CM, Israel M, Sweatman TW. N-benzyladriamycin-14-valerate (AD 198) activates protein kinase C-delta holoenzyme to trigger mitochondrial depolarization and cytochrome c release independently of permeability transition pore opening and Ca2+ influx. Anti-Cancer Drugs. 17: 495-502. PMID 16702805 DOI: 10.1097/00001813-200606000-00002 |
0.484 |
|
2006 |
Fischer TW, Zbytek B, Sayre RM, Apostolov EO, Basnakian AG, Sweatman TW, Wortsman J, Elsner P, Slominski A. Melatonin increases survival of HaCaT keratinocytes by suppressing UV-induced apoptosis Journal of Pineal Research. 40: 18-26. PMID 16313494 DOI: 10.1111/J.1600-079X.2005.00273.X |
0.343 |
|
2005 |
He Y, Liu J, Durrant D, Yang HS, Sweatman T, Lothstein L, Lee RM. N-benzyladriamycin-14-valerate (AD198) induces apoptosis through protein kinase C-delta-induced phosphorylation of phospholipid scramblase 3. Cancer Research. 65: 10016-23. PMID 16267027 DOI: 10.1158/0008-5472.CAN-05-1688 |
0.342 |
|
2004 |
Slominski A, Zjawiony J, Wortsman J, Semak I, Stewart J, Pisarchik A, Sweatman T, Marcos J, Dunbar C, C Tuckey R. A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin. European Journal of Biochemistry / Febs. 271: 4178-88. PMID 15511223 DOI: 10.1111/J.1432-1033.2004.04356.X |
0.324 |
|
2004 |
Bilyeu JD, Panta GR, Cavin LG, Barrett CM, Turner EJ, Sweatman TW, Israel M, Lothstein L, Arsura M. Circumvention of nuclear factor kappaB-induced chemoresistance by cytoplasmic-targeted anthracyclines. Molecular Pharmacology. 65: 1038-47. PMID 15044634 DOI: 10.1124/Mol.65.4.1038 |
0.399 |
|
2004 |
Panta GR, Kaur S, Cavin LG, Cortés ML, Mercurio F, Lothstein L, Sweatman TW, Israel M, Arsura M. ATM and the catalytic subunit of DNA-dependent protein kinase activate NF-kappaB through a common MEK/extracellular signal-regulated kinase/p90(rsk) signaling pathway in response to distinct forms of DNA damage. Molecular and Cellular Biology. 24: 1823-35. PMID 14966265 DOI: 10.1128/Mcb.24.5.1823-1835.2004 |
0.344 |
|
2002 |
Roaten JB, Kazanietz MG, Caloca MJ, Bertics PJ, Lothstein L, Parrill AL, Israel M, Sweatman TW. Interaction of the novel anthracycline antitumor agent N-benzyladriamycin-14-valerate with the C1-regulatory domain of protein kinase C: structural requirements, isoform specificity, and correlation with drug cytotoxicity. Molecular Cancer Therapeutics. 1: 483-92. PMID 12479266 |
0.745 |
|
2002 |
Barrett CM, Lewis FL, Roaten JB, Sweatman TW, Israel M, Cleveland JL, Lothstein L. Novel extranuclear-targeted anthracyclines override the antiapoptotic functions of Bcl-2 and target protein kinase C pathways to induce apoptosis. Molecular Cancer Therapeutics. 1: 469-81. PMID 12479265 |
0.728 |
|
2002 |
Slominski A, Semak I, Pisarchik A, Sweatman T, Szczesniewski A, Wortsman J. Conversion of L-tryptophan to serotonin and melatonin in human melanoma cells. Febs Letters. 511: 102-6. PMID 11821057 DOI: 10.1016/S0014-5793(01)03319-1 |
0.325 |
|
2001 |
Lothstein L, Israel M, Sweatman TW. Anthracycline drug targeting: Cytoplasmic versus nuclear - A fork in the road Drug Resistance Updates. 4: 169-177. PMID 11768330 DOI: 10.1054/Drup.2001.0201 |
0.39 |
|
2001 |
Roaten JB, Kazanietz MG, Sweatman TW, Lothstein L, Israel M, Parrill AL. Molecular models of N-benzyladriamycin-14-valerate (AD 198) in complex with the phorbol ester-binding C1b domain of protein kinase C-delta. Journal of Medicinal Chemistry. 44: 1028-34. PMID 11297449 DOI: 10.1021/Jm000289V |
0.727 |
|
2000 |
Wani MK, Koseki Y, Yarber RH, Sweatman TW, Ahmed A, Samant S, Hengesteg A, Israel M, Robbins KT. Rationale for intralesional valrubicin in chemoradiation of squamous cell carcinoma of the head and neck Laryngoscope. 110: 2026-2032. PMID 11129014 DOI: 10.1097/00005537-200012000-00009 |
0.329 |
|
2000 |
Lothstein L, Suttle DP, Roaten JB, Koseki Y, Israel M, Sweatman TW. Catalytic inhibition of DNA topoisomerase II by N-benzyladriamycin (AD 288). Biochemical Pharmacology. 60: 1621-8. PMID 11077044 DOI: 10.1016/S0006-2952(00)00472-X |
0.714 |
|
1999 |
Sweatman TW, Seshadri R, Israel M. Pharmacology of N-benzyladriamycin-14-valerate in the rat Cancer Chemotherapy and Pharmacology. 43: 419-426. PMID 10100599 DOI: 10.1007/S002800050917 |
0.437 |
|
1998 |
Pawlik CA, Israel M, Sweatman TW, Lothstein L. Cellular resistance against the novel hybrid anthracycline N-(2-Chloroethyl)-N-nitrosoureidodaunorubicin (AD 312) is mediated by combined altered topoisomerase II and O6-methylguanine-DNA methyltransferase activities Oncology Research. 10: 209-217. PMID 9778692 |
0.356 |
|
1998 |
Lothstein L, Rodrigues PJ, Sweatman TW, Israel M. Cytotoxicity and intracellular biotransformation of N-benzyladriamycin- 14-valerate (AD 198) are modulated by changes in 14-O-acyl chain length Anti-Cancer Drugs. 9: 58-66. PMID 9491793 DOI: 10.1097/00001813-199801000-00007 |
0.442 |
|
1997 |
Greenberg RE, Bahnson RR, Wood D, Childs SJ, Bellingham C, Edson M, Bamberger MH, Steinberg GD, Israel M, Sweatman T, Giantonio B, O'Dwyer PJ. Initial report on intravesical administration of N- trifluoroacetyladriamycin-14-valerate (AD 32) to patients with refractory superficial transitional cell carcinoma of the urinary bladder Urology. 49: 471-475. PMID 9123721 DOI: 10.1016/S0090-4295(96)00621-8 |
0.39 |
|
1996 |
Markman M, Homesley H, Norberts DA, Schink J, Abbas F, Miller A, Soper J, Teng N, Hammond N, Muggia F, Israel M, Sweatman T. Phase 1 Trial of Intraperitoneal AD-32 in Gynecologic Malignancies Gynecologic Oncology. 61: 90-93. PMID 8626124 DOI: 10.1006/Gyno.1996.0102 |
0.358 |
|
1996 |
Han G, Israel M, Seshadri R, Dalton JT, Sweatman TW. Pharmacology of N,N-di(n-butyl)adriamycin-14-valerate in the rat. Cancer Chemotherapy and Pharmacology. 37: 472-8. PMID 8599871 DOI: 10.1007/S002800050414 |
0.353 |
|
1995 |
Lothstein L, Sweatman TW, Priebe W. Hydroxylation at C-3′ of doxorubicin alters the selected phenotype of cellular drug resistance Bioorganic and Medicinal Chemistry Letters. 5: 1807-1812. DOI: 10.1016/0960-894X(95)00300-I |
0.325 |
|
1994 |
Lothstein L, Koseki Y, Sweatman TW. P-glycoprotein overexpression in mouse cells does not correlate with resistance to N-benzyladriamycin-14-valerate (AD 198) Anti-Cancer Drugs. 5: 623-633. PMID 7888699 DOI: 10.1097/00001813-199412000-00003 |
0.391 |
|
1992 |
Lothstein L, Wright HM, Sweatman TW, Israel M. N-Benzyladriamycin-14-valerate and drug resistance: Correlation of anthracycline structural modification with intracellular accumulation and distribution in multidrug resistant cells Oncology Research. 4: 341-347. PMID 1362503 |
0.324 |
|
1992 |
Lothstein L, Sweatman TW, Dockter ME, Israel M. Resistance to iV-Benzyladriamycin-14-valerate in Mouse J774.2 Cells: P-Glycoprotein Expression without Reduced 7V-Benzyladriamycin-14-valerate Accumulation Cancer Research. 52: 3409-3417. PMID 1350753 |
0.343 |
|
1991 |
Sweatman TW, Parker RF, Israel M. Pharmacologic rationale for intravesical N-Trifluoroacetyladriamycin-14-valerate (AD 32): a preclinical study Cancer Chemotherapy and Pharmacology. 28: 1-6. PMID 2040028 DOI: 10.1007/Bf00684948 |
0.398 |
|
1990 |
Kashfi K, Israel M, Sweatman TW, Seshadri R, Cook GA. Inhibition of mitochondrial carnitine palmitoyltransferases by adriamycin and adriamycin analogues Biochemical Pharmacology. 40: 1441-1448. PMID 2222502 DOI: 10.1016/0006-2952(90)90438-Q |
0.364 |
|
1989 |
Israel M, Sweatman TW, Seshadri R, Koseki Y. Comparative uptake and retention of adriamycin and N-benzyladriamycin-14-valerate in human CEM leukemic lymphocyte cell cultures Cancer Chemotherapy and Pharmacology. 25: 177-183. PMID 2598408 DOI: 10.1007/Bf00689579 |
0.414 |
|
1987 |
Sweatman TW, Israel M. Comparative metabolism and elimination of adriamycin and 4′-epiadriamycin in the rat Cancer Chemotherapy and Pharmacology. 19: 201-206. PMID 3472675 DOI: 10.1007/Bf00252973 |
0.306 |
|
1987 |
Israel M, Seshadri R, Koseki Y, Sweatman TW, Idriss JM. Amelioration of adriamycin toxicity through modification of drug-DNA binding properties Cancer Treatment Reviews. 14: 163-167. PMID 3440247 DOI: 10.1016/0305-7372(87)90003-X |
0.332 |
|
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