| Year |
Citation |
Score |
| 2022 |
Xi W, Sun H, Bastow KF, Xiao Z, Lee KH. Identification of Novel 4'--Demethyl-epipodophyllotoxin Derivatives as Antitumor Agents Targeting Topoisomerase II. Molecules (Basel, Switzerland). 27. PMID 35956979 DOI: 10.3390/molecules27155029 |
0.476 |
|
| 2013 |
Wang XF, Ohkoshi E, Wang SB, Hamel E, Bastow KF, Morris-Natschke SL, Lee KH, Xie L. Synthesis and biological evaluation of N-alkyl-N-(4-methoxyphenyl)pyridin-2-amines as a new class of tubulin polymerization inhibitors. Bioorganic & Medicinal Chemistry. 21: 632-42. PMID 23274123 DOI: 10.1016/j.bmc.2012.11.047 |
0.4 |
|
| 2013 |
Wang Q, Chen TH, Bastow KF, Morris-Natschke SL, Lee KH, Chen DF. Songaricalarins A-E, cytotoxic oplopane sesquiterpenes from Ligularia songarica. Journal of Natural Products. 76: 305-10. PMID 23043462 DOI: 10.1021/np300532p |
0.301 |
|
| 2012 |
Wang XF, Tian XT, Ohkoshi E, Qin B, Liu YN, Wu PC, Hour MJ, Hung HY, Qian K, Huang R, Bastow KF, Janzen WP, Jin J, Morris-Natschke SL, Lee KH, et al. Design and synthesis of diarylamines and diarylethers as cytotoxic antitumor agents. Bioorganic & Medicinal Chemistry Letters. 22: 6224-8. PMID 22932313 DOI: 10.1016/J.Bmcl.2012.08.014 |
0.422 |
|
| 2012 |
Yang X, Shi Q, Lai CY, Chen CY, Ohkoshi E, Yang SC, Wang CY, Bastow KF, Wu TS, Pan SL, Teng CM, Yang PC, Lee KH. Antitumor agents 295. E-ring hydroxylated antofine and cryptopleurine analogues as antiproliferative agents: design, synthesis, and mechanistic studies. Journal of Medicinal Chemistry. 55: 6751-61. PMID 22823514 DOI: 10.1021/jm3001218 |
0.384 |
|
| 2012 |
Hung HY, Ohkoshi E, Goto M, Bastow KF, Nakagawa-Goto K, Lee KH. Antitumor agents. 293. Nontoxic dimethyl-4,4'-dimethoxy-5,6,5',6'-dimethylenedioxybiphenyl-2,2'-dicarboxylate (DDB) analogues chemosensitize multidrug-resistant cancer cells to clinical anticancer drugs. Journal of Medicinal Chemistry. 55: 5413-24. PMID 22612652 DOI: 10.1021/jm300378k |
0.355 |
|
| 2012 |
Yen CT, Nakagawa-Goto K, Hwang TL, Morris-Natschke SL, Bastow KF, Wu YC, Lee KH. Design and synthesis of gambogic acid analogs as potent cytotoxic and anti-inflammatory agents. Bioorganic & Medicinal Chemistry Letters. 22: 4018-22. PMID 22595179 DOI: 10.1016/j.bmcl.2012.04.084 |
0.38 |
|
| 2012 |
Zhou T, Ohkoshi E, Shi Q, Bastow KF, Lee KH. Anti-AIDS agents 89. Identification of DCX derivatives as anti-HIV and chemosensitizing dual function agents to overcome P-gp-mediated drug resistance for AIDS therapy. Bioorganic & Medicinal Chemistry Letters. 22: 3219-22. PMID 22465634 DOI: 10.1016/j.bmcl.2012.03.037 |
0.304 |
|
| 2012 |
Dong Y, Nakagawa-Goto K, Lai CY, Morris-Natschke SL, Bastow KF, Kim Y, Lee EY, Lee KH. Antitumor agents. 289. Design, synthesis, and anti-breast cancer activity in vivo of 4-amino-2H-benzo[h]chromen-2-one and 4-amino-7,8,9,10-tetrahydro-2H-benzo[h]chromen-2-one analogues with improved water solubility. Journal of Natural Products. 75: 370-7. PMID 22304236 DOI: 10.1021/Np2007878 |
0.35 |
|
| 2012 |
Wada K, Ohkoshi E, Morris-Natschke SL, Bastow KF, Lee KH. Cytotoxic esterified diterpenoid alkaloid derivatives with increased selectivity against a drug-resistant cancer cell line. Bioorganic & Medicinal Chemistry Letters. 22: 249-52. PMID 22142543 DOI: 10.1055/S-0032-1320369 |
0.465 |
|
| 2012 |
Vijaya Bhaskar Reddy M, Shen YC, Ohkoshi E, Bastow KF, Qian K, Lee KH, Wu TS. Bis-chalcone analogues as potent NO production inhibitors and as cytotoxic agents. European Journal of Medicinal Chemistry. 47: 97-103. PMID 22115618 DOI: 10.1016/J.Ejmech.2011.10.026 |
0.495 |
|
| 2011 |
Nakagawa-Goto K, Bastow KF, Ohkoshi E, Morris-Natschke SL, Lee KH. Antitumor Agents 291 Expanded B-Ring Modification Study of 6,8,8-Triethyl Desmosdumotin B Analogues as Multidrug-Resistance Selective Agents. Medicinal Chemistry. 1. PMID 23293751 DOI: 10.4172/2161-0444.1000101 |
0.429 |
|
| 2011 |
Yang X, Shi Q, Yang SC, Chen CY, Yu SL, Bastow KF, Morris-Natschke SL, Wu PC, Lai CY, Wu TS, Pan SL, Teng CM, Lin JC, Yang PC, Lee KH. Antitumor agents 288: design, synthesis, SAR, and biological studies of novel heteroatom-incorporated antofine and cryptopleurine analogues as potent and selective antitumor agents. Journal of Medicinal Chemistry. 54: 5097-107. PMID 21668000 DOI: 10.1021/jm200330s |
0.486 |
|
| 2011 |
Dong Y, Nakagawa-Goto K, Lai CY, Morris-Natschke SL, Bastow KF, Lee KH. Antitumor agents 287. Substituted 4-amino-2H-pyran-2-one (APO) analogs reveal a new scaffold from neo-tanshinlactone with in vitro anticancer activity. Bioorganic & Medicinal Chemistry Letters. 21: 2341-4. PMID 21420855 DOI: 10.1016/J.Bmcl.2011.02.084 |
0.358 |
|
| 2011 |
Chan HH, Hwang TL, Reddy MV, Li DT, Qian K, Bastow KF, Lee KH, Wu TS. Bioactive constituents from the roots of Panax japonicus var. major and development of a LC-MS/MS method for distinguishing between natural and artifactual compounds. Journal of Natural Products. 74: 796-802. PMID 21417387 DOI: 10.1021/Np100851S |
0.322 |
|
| 2011 |
Reddy MV, Shen YC, Yang JS, Hwang TL, Bastow KF, Qian K, Lee KH, Wu TS. New bichalcone analogs as NF-κB inhibitors and as cytotoxic agents inducing Fas/CD95-dependent apoptosis. Bioorganic & Medicinal Chemistry. 19: 1895-906. PMID 21377368 DOI: 10.1016/J.Bmc.2011.02.004 |
0.439 |
|
| 2011 |
Nakagawa-Goto K, Wu PC, Bastow KF, Yang SC, Yu SL, Chen HY, Lin JC, Goto M, Morris-Natschke SL, Yang PC, Lee KH. Antitumor agents 283. Further elaboration of desmosdumotin C analogs as potent antitumor agents: activation of spindle assembly checkpoint as possible mode of action. Bioorganic & Medicinal Chemistry. 19: 1816-22. PMID 21296579 DOI: 10.1016/j.bmc.2011.01.001 |
0.417 |
|
| 2011 |
Nakagawa-Goto K, Wu PC, Lai CY, Hamel E, Zhu H, Zhang L, Kozaka T, Ohkoshi E, Goto M, Bastow KF, Lee KH. Antitumor agents. 284. New desmosdumotin B analogues with bicyclic B-ring as cytotoxic and antitubulin agents. Journal of Medicinal Chemistry. 54: 1244-55. PMID 21284385 DOI: 10.1021/Jm1011947 |
0.35 |
|
| 2011 |
Dong Y, Nakagawa-Goto K, Lai CY, Kim Y, Morris-Natschke SL, Lee EY, Bastow KF, Lee KH. Antitumor agents 279. Structure-activity relationship and in vivo studies of novel 2-(furan-2-yl)naphthalen-1-ol (FNO) analogs as potent and selective anti-breast cancer agents. Bioorganic & Medicinal Chemistry Letters. 21: 52-7. PMID 21147529 DOI: 10.1016/J.Bmcl.2010.11.077 |
0.361 |
|
| 2011 |
Dong Y, Nakagawa-Goto K, Lai CY, Morris-Natschke SL, Bastow KF, Lee KH. Antitumor agents 281. Design, synthesis, and biological activity of substituted 4-amino-7,8,9,10-tetrahydro-2H-benzo[h]chromen-2-one analogs (ATBO) as potent in vitro anticancer agents. Bioorganic & Medicinal Chemistry Letters. 21: 546-9. PMID 21087859 DOI: 10.1016/J.Bmcl.2010.10.074 |
0.431 |
|
| 2011 |
Dong Y, Nakagawa-Goto K, Lai C, Morris-Natschke SL, Bastow KF, Lee K. ChemInform Abstract: Antitumor Agents. Part 287. Substituted 4-Amino-2H-pyran-2-one (APO) Analogues Reveal a New Scaffold from Neo-Tanshinlactone with in vitro Anticancer Activity. Cheminform. 42: no-no. DOI: 10.1002/CHIN.201134207 |
0.35 |
|
| 2010 |
Zhou T, Shi Q, Bastow KF, Lee KH. Antitumor agents 286. Design, synthesis, and structure-activity relationships of 3'R,4'R-disubstituted-2',2'-dimethyldihydropyrano[2,3-f]chromone (DSP) analogues as potent chemosensitizers to overcome multidrug resistance. Journal of Medicinal Chemistry. 53: 8700-8. PMID 21082774 DOI: 10.1021/jm101249z |
0.341 |
|
| 2010 |
Wu SJ, Leu YL, Chen CH, Chao CH, Shen DY, Chan HH, Lee EJ, Wu TS, Wang YH, Shen YC, Qian K, Bastow KF, Lee KH. Camphoratins A-J, potent cytotoxic and anti-inflammatory triterpenoids from the fruiting body of Taiwanofungus camphoratus. Journal of Natural Products. 73: 1756-62. PMID 21028898 DOI: 10.1021/Np1002143 |
0.443 |
|
| 2010 |
Usami Y, Nakagawa-Goto K, Lang JY, Kim Y, Lai CY, Goto M, Sakurai N, Taniguchi M, Akiyama T, Morris-Natschke SL, Bastow KF, Cragg G, Newman DJ, Fujitake M, Takeya K, et al. Antitumor Agents. 282. 2'-(R)-O-acetylglaucarubinone, a quassinoid from Odyendyea gabonensis as a potential anti-breast and anti-ovarian cancer agent. Journal of Natural Products. 73: 1553-8. PMID 20738103 DOI: 10.1021/np100406d |
0.301 |
|
| 2010 |
Nakagawa-Goto K, Chang PC, Lai CY, Hung HY, Chen TH, Wu PC, Zhu H, Sedykh A, Bastow KF, Lee KH. Antitumor agents. 280. Multidrug resistance-selective desmosdumotin B analogues. Journal of Medicinal Chemistry. 53: 6699-705. PMID 20735140 DOI: 10.1021/Jm100846R |
0.371 |
|
| 2010 |
Dong Y, Nakagawa-Goto K, Lai CY, Morris-Natschke SL, Bastow KF, Lee KH. Antitumor agents 278. 4-Amino-2H-benzo[h]chromen-2-one (ABO) analogs as potent in vitro anti-cancer agents. Bioorganic & Medicinal Chemistry Letters. 20: 4085-7. PMID 20542429 DOI: 10.1016/J.Bmcl.2010.05.079 |
0.395 |
|
| 2010 |
Kozaka T, Nakagawa-Goto K, Shi Q, Lai CY, Hamel E, Bastow KF, Brossi A, Lee KH. Antitumor agents 273. Design and synthesis of N-alkyl-thiocolchicinoids as potential antitumor agents Bioorganic and Medicinal Chemistry Letters. 20: 4091-4094. PMID 20542428 DOI: 10.1016/j.bmcl.2010.05.081 |
0.368 |
|
| 2010 |
Zhang LJ, Chiou CT, Cheng JJ, Huang HC, Kuo LM, Liao CC, Bastow KF, Lee KH, Kuo YH. Cytotoxic polyisoprenyl benzophenonoids from Garcinia subelliptica. Journal of Natural Products. 73: 557-62. PMID 20232858 DOI: 10.1021/np900620y |
0.397 |
|
| 2010 |
Dong Y, Shi Q, Pai HC, Peng CY, Pan SL, Teng CM, Nakagawa-Goto K, Yu D, Liu YN, Wu PC, Bastow KF, Morris-Natschke SL, Brossi A, Lang JY, Hsu JL, et al. Antitumor agents. 272. Structure-activity relationships and in vivo selective anti-breast cancer activity of novel neo-tanshinlactone analogues. Journal of Medicinal Chemistry. 53: 2299-308. PMID 20148565 DOI: 10.1021/Jm1000858 |
0.444 |
|
| 2010 |
Yen CT, Nakagawa-Goto K, Hwang TL, Wu PC, Morris-Natschke SL, Lai WC, Bastow KF, Chang FR, Wu YC, Lee KH. Antitumor agents. 271: total synthesis and evaluation of brazilein and analogs as anti-inflammatory and cytotoxic agents. Bioorganic & Medicinal Chemistry Letters. 20: 1037-9. PMID 20036537 DOI: 10.1016/j.bmcl.2009.12.041 |
0.428 |
|
| 2010 |
Dong Y, Shi Q, Nakagawa-Goto K, Wu PC, Morris-Natschke SL, Brossi A, Bastow KF, Lang JY, Hung MC, Lee KH. Antitumor agents 270. Novel substituted 6-phenyl-4H-furo[3,2-c]pyran-4-one derivatives as potent and highly selective anti-breast cancer agents. Bioorganic & Medicinal Chemistry. 18: 803-8. PMID 20034799 DOI: 10.1016/J.Bmc.2009.11.049 |
0.314 |
|
| 2010 |
Nishiyama Y, Iwasa K, Okada S, Takeuchi S, Moriyasu M, Kamigauchi M, Koyama J, Takeuchi A, Tokuda H, Kim HS, Wataya Y, Takeda K, Liu YN, Wu PC, Bastow KF, et al. Geranyl derivatives of isoquinoline alkaloids show increased biological activities Heterocycles. 81: 1193-1229. DOI: 10.3987/COM-10-11912 |
0.382 |
|
| 2009 |
Dong Y, Shi Q, Nakagawa-Goto K, Wu PC, Bastow KF, Morris-Natschke SL, Lee KH. Antitumor agents 269. Non-aromatic ring-A neotanshinlactone analog, TNO, as a new class of potent antitumor agents. Bioorganic & Medicinal Chemistry Letters. 19: 6289-92. PMID 19819136 DOI: 10.1016/J.Bmcl.2009.09.092 |
0.479 |
|
| 2009 |
Yang X, Shi Q, Liu YN, Zhao G, Bastow KF, Lin JC, Yang SC, Yang PC, Lee KH. Antitumor agents 268. Design, synthesis, and mechanistic studies of new 9-substituted phenanthrene-based tylophorine analogues as potent cytotoxic agents. Journal of Medicinal Chemistry. 52: 5262-8. PMID 19645447 DOI: 10.1021/Jm9009263 |
0.483 |
|
| 2009 |
Su CR, Yeh SF, Liu CM, Damu AG, Kuo TH, Chiang PC, Bastow KF, Lee KH, Wu TS. Anti-HBV and cytotoxic activities of pyranocoumarin derivatives. Bioorganic & Medicinal Chemistry. 17: 6137-43. PMID 19635670 DOI: 10.1016/j.bmc.2008.12.007 |
0.442 |
|
| 2009 |
Dong Y, Shi Q, Liu YN, Wang X, Bastow KF, Lee KH. Antitumor agents. 266. Design, synthesis, and biological evaluation of novel 2-(furan-2-yl)naphthalen-1-ol derivatives as potent and selective antibreast cancer agents. Journal of Medicinal Chemistry. 52: 3586-90. PMID 19425534 DOI: 10.1021/Jm9001567 |
0.432 |
|
| 2009 |
Lee CL, Chang FR, Yen MH, Yu D, Liu YN, Bastow KF, Morris-Natschke SL, Wu YC, Lee KH. Cytotoxic phenanthrenequinones and 9,10-dihydrophenanthrenes from Calanthe arisanensis. Journal of Natural Products. 72: 210-3. PMID 19193043 DOI: 10.1021/Np800622A |
0.388 |
|
| 2008 |
Wu G, Guo HF, Gao K, Liu YN, Bastow KF, Morris-Natschke SL, Lee KH, Xie L. Synthesis of unsymmetrical biphenyls as potent cytotoxic agents. Bioorganic & Medicinal Chemistry Letters. 18: 5272-6. PMID 18782668 DOI: 10.1016/j.bmcl.2008.08.050 |
0.486 |
|
| 2008 |
Lee CL, Nakagawa-Goto K, Yu D, Liu YN, Bastow KF, Morris-Natschke SL, Chang FR, Wu YC, Lee KH. Cytotoxic calanquinone A from Calanthe arisanensis and its first total synthesis. Bioorganic & Medicinal Chemistry Letters. 18: 4275-7. PMID 18640035 DOI: 10.1016/j.bmcl.2008.06.099 |
0.323 |
|
| 2008 |
Reddy MV, Su CR, Chiou WF, Liu YN, Chen RY, Bastow KF, Lee KH, Wu TS. Design, synthesis, and biological evaluation of Mannich bases of heterocyclic chalcone analogs as cytotoxic agents. Bioorganic & Medicinal Chemistry. 16: 7358-70. PMID 18602831 DOI: 10.1016/j.bmc.2008.06.018 |
0.467 |
|
| 2008 |
Nakagawa-Goto K, Bastow KF, Chen TH, Morris-Natschke SL, Lee KH. Antitumor agents 260. New desmosdumotin B analogues with improved in vitro anticancer activity. Journal of Medicinal Chemistry. 51: 3297-303. PMID 18473435 DOI: 10.1021/jm701208v |
0.49 |
|
| 2008 |
Su CR, Damu AG, Chiang PC, Bastow KF, Morris-Natschke SL, Lee KH, Wu TS. Total synthesis of phenanthroindolizidine alkaloids (+/-)-antofine, (+/-)-deoxypergularinine, and their dehydro congeners and evaluation of their cytotoxic activity. Bioorganic & Medicinal Chemistry. 16: 6233-41. PMID 18456501 DOI: 10.1016/j.bmc.2008.04.032 |
0.368 |
|
| 2008 |
Usami Y, Liu YN, Lin AS, Shibano M, Akiyama T, Itokawa H, Morris-Natschke SL, Bastow K, Kasai R, Lee KH. Antitumor agents. 261. 20(S)-protopanaxadiol and 20(s)-protopanaxatriol as antiangiogenic agents and total assignment of (1)H NMR spectra. Journal of Natural Products. 71: 478-81. PMID 18271556 DOI: 10.1021/Np070613Q |
0.381 |
|
| 2008 |
Peng CY, Pan SL, Lee KH, Bastow KF, Teng CM. Molecular mechanism of the inhibitory effect of KS-5 on bFGF-induced angiogenesis in vitro and in vivo. Cancer Letters. 263: 114-21. PMID 18243528 DOI: 10.1016/j.canlet.2007.12.028 |
0.301 |
|
| 2008 |
Wei L, Brossi A, Morris-Natschke SL, Bastow KF, Lee KH. Antitumor agents 248. Chemistry and antitumor activity of tylophorinerelated alkaloids Studies in Natural Products Chemistry. 34: 3-34. DOI: 10.1016/S1572-5995(08)80023-3 |
0.437 |
|
| 2007 |
Nakagawa-Goto K, Yamada K, Nakamura S, Chen TH, Chiang PC, Bastow KF, Wang SC, Spohn B, Hung MC, Lee FY, Lee FC, Lee KH. Antitumor agents. 258. Syntheses and evaluation of dietary antioxidant--taxoid conjugates as novel cytotoxic agents. Bioorganic & Medicinal Chemistry Letters. 17: 5204-9. PMID 17643301 DOI: 10.1016/j.bmcl.2007.06.083 |
0.419 |
|
| 2007 |
Zhou LB, Chen TH, Bastow KF, Shibano M, Lee KH, Chen DF. Filiasparosides A-D, cytotoxic steroidal saponins from the roots of Asparagus filicinus. Journal of Natural Products. 70: 1263-7. PMID 17629328 DOI: 10.1021/Np070138W |
0.351 |
|
| 2007 |
Wei L, Shi Q, Bastow KF, Brossi A, Morris-Natschke SL, Nakagawa-Goto K, Wu TS, Pan SL, Teng CM, Lee KH. Antitumor agents 253. Design, synthesis, and antitumor evaluation of novel 9-substituted phenanthrene-based tylophorine derivatives as potential anticancer agents. Journal of Medicinal Chemistry. 50: 3674-80. PMID 17585747 DOI: 10.1021/Jm061366A |
0.443 |
|
| 2007 |
Damu AG, Kuo PC, Su CR, Kuo TH, Chen TH, Bastow KF, Lee KH, Wu TS. Isolation, structures, and structure - cytotoxic activity relationships of withanolides and physalins from Physalis angulata. Journal of Natural Products. 70: 1146-52. PMID 17580910 DOI: 10.1021/np0701374 |
0.401 |
|
| 2007 |
Nakagawa-Goto K, Chen TH, Peng CY, Bastow KF, Wu JH, Lee KH. Antitumor agents 259. Design, syntheses, and structure-activity relationship study of desmosdumotin C analogs. Journal of Medicinal Chemistry. 50: 3354-8. PMID 17569518 DOI: 10.1021/jm0702534 |
0.445 |
|
| 2007 |
Rosselli S, Bruno M, Maggio A, Bellone G, Chen TH, Bastow KF, Lee KH. Cytotoxic activity of some natural and synthetic ent-kauranes. Journal of Natural Products. 70: 347-52. PMID 17378530 DOI: 10.1021/Np060504W |
0.463 |
|
| 2007 |
Nakagawa-Goto K, Nakamura S, Bastow KF, Nyarko A, Peng CY, Lee FY, Lee FC, Lee KH. Antitumor agents. 256. Conjugation of paclitaxel with other antitumor agents: evaluation of novel conjugates as cytotoxic agents. Bioorganic & Medicinal Chemistry Letters. 17: 2894-8. PMID 17350834 DOI: 10.1016/j.bmcl.2007.02.051 |
0.394 |
|
| 2006 |
Wu PL, Hsu YL, Wu TS, Bastow KF, Lee KH. Kalanchosides A-C, new cytotoxic bufadienolides from the aerial parts of Kalanchoe gracilis. Organic Letters. 8: 5207-10. PMID 17078679 DOI: 10.1021/Ol061873M |
0.425 |
|
| 2006 |
Tatsuzaki J, Bastow KF, Nakagawa-Goto K, Nakamura S, Itokawa H, Lee KH. Dehydrozingerone, chalcone, and isoeugenol analogues as in vitro anticancer agents. Journal of Natural Products. 69: 1445-9. PMID 17067159 DOI: 10.1021/np060252z |
0.418 |
|
| 2006 |
Horiuch M, Murakami C, Fukamiya N, Yu D, Chen TH, Bastow KF, Zhang DC, Takaishi Y, Imakura Y, Lee KH. Tripfordines A-C, sesquiterpene pyridine alkaloids from Tripterygium wilfordii, and structure anti-HIV activity relationships of Tripterygium alkaloids. Journal of Natural Products. 69: 1271-4. PMID 16989518 DOI: 10.1021/Np060124A |
0.302 |
|
| 2006 |
Wang X, Nakagawa-Goto K, Bastow KF, Don MJ, Lin YL, Wu TS, Lee KH. Antitumor agents. 254. Synthesis and biological evaluation of novel neo-tanshinlactone analogues as potent anti-breast cancer agents. Journal of Medicinal Chemistry. 49: 5631-4. PMID 16942038 DOI: 10.1021/Jm060184D |
0.425 |
|
| 2006 |
Wei L, Brossi A, Kendall R, Bastow KF, Morris-Natschke SL, Shi Q, Lee KH. Antitumor agents 251: synthesis, cytotoxic evaluation, and structure-activity relationship studies of phenanthrene-based tylophorine derivatives (PBTs) as a new class of antitumor agents. Bioorganic & Medicinal Chemistry. 14: 6560-9. PMID 16809043 DOI: 10.1016/J.Bmc.2006.06.009 |
0.459 |
|
| 2006 |
Lin L, Shi Q, Nyarko AK, Bastow KF, Wu CC, Su CY, Shih CC, Lee KH. Antitumor agents. 250. Design and synthesis of new curcumin analogues as potential anti-prostate cancer agents. Journal of Medicinal Chemistry. 49: 3963-72. PMID 16789753 DOI: 10.1021/jm051043z |
0.345 |
|
| 2006 |
Sakurai Y, Sakurai N, Taniguchi M, Nakanishi Y, Bastow KF, Wang X, Cragg GM, Lee KH. Rautandiols A and B, pterocarpans and cytotoxic constituents from Neorautanenia mitis. Journal of Natural Products. 69: 397-9. PMID 16562843 DOI: 10.1021/Np058070C |
0.399 |
|
| 2006 |
Sakurai N, Nakagawa-Goto K, Ito J, Sakurai Y, Nakanishi Y, Bastow KF, Cragg G, Lee KH. Cytotoxic Alangium alkaloids from Alangium longiflorum. Phytochemistry. 67: 894-7. PMID 16530796 DOI: 10.1016/j.phytochem.2006.01.009 |
0.364 |
|
| 2006 |
Akanitapichat P, Wangmaneerat A, Wilairat P, Bastow KF. Anti-herpes virus activity of Dunbaria bella Prain. Journal of Ethnopharmacology. 105: 64-8. PMID 16298095 DOI: 10.1016/j.jep.2005.09.035 |
0.41 |
|
| 2005 |
Bruno M, Rosselli S, Maggio A, Raccuglia RA, Bastow KF, Wu CC, Lee KH. Cytotoxic activity of some natural and synthetic sesquiterpene lactones. Planta Medica. 71: 1176-8. PMID 16395659 DOI: 10.1055/s-2005-873139 |
0.403 |
|
| 2005 |
Bruno M, Rosselli S, Maggio A, Raccuglia RA, Bastow KF, Lee KH. Cytotoxic activity of some natural and synthetic guaianolides. Journal of Natural Products. 68: 1042-6. PMID 16038545 DOI: 10.1021/np0500575 |
0.465 |
|
| 2005 |
Nakamura S, Kozuka M, Bastow KF, Tokuda H, Nishino H, Suzuki M, Tatsuzaki J, Morris Natschke SL, Kuo SC, Lee KH. Cancer preventive agents, Part 2: Synthesis and evaluation of 2-phenyl-4-quinolone and 9-oxo-9,10-dihydroacridine derivatives as novel antitumor promoters. Bioorganic & Medicinal Chemistry. 13: 4396-401. PMID 15914009 DOI: 10.1016/J.Bmc.2005.04.078 |
0.486 |
|
| 2005 |
Nakagawa-Goto K, Bastow KF, Wu JH, Tokuda H, Lee KH. Total synthesis and bioactivity of unique flavone desmosdumotin B and its analogs. Bioorganic & Medicinal Chemistry Letters. 15: 3016-9. PMID 15913998 DOI: 10.1016/j.bmcl.2005.04.070 |
0.463 |
|
| 2005 |
Nakagawa-Goto K, Wu JH, Bastow KF, Wu CC, Lee KH. Antitumor agents 243. Syntheses and cytotoxicity of desmosdumotin C derivatives. Bioorganic & Medicinal Chemistry. 13: 2325-30. PMID 15727881 DOI: 10.1016/j.bmc.2004.12.040 |
0.411 |
|
| 2005 |
Lai YY, Huang LJ, Lee KH, Xiao Z, Bastow KF, Yamori T, Kuo SC. Synthesis and biological relationships of 3',6-substituted 2-phenyl-4-quinolone-3-carboxylic acid derivatives as antimitotic agents. Bioorganic & Medicinal Chemistry. 13: 265-75. PMID 15582470 DOI: 10.1016/j.bmc.2004.09.041 |
0.367 |
|
| 2005 |
Nakagawa-Goto K, Jung MK, Hamel E, Wu CC, Bastow KF, Brossi A, Ohta S, Lee KH. Antitumor agents 238. Anti-tubulin and in vitrocytotoxic effects of N-substituted allocolchicinoids Heterocycles. 65: 541-550. DOI: 10.3987/Com-04-10244 |
0.402 |
|
| 2004 |
Bastow KF. New acridone inhibitors of human herpes virus replication Current Drug Targets - Infectious Disorders. 4: 323-330. PMID 15578973 DOI: 10.2174/1568005043340533 |
0.435 |
|
| 2004 |
Tanaka N, Takaishi Y, Shikishima Y, Nakanishi Y, Bastow K, Lee KH, Honda G, Ito M, Takeda Y, Kodzhimatov OK, Ashurmetov O. Prenylated benzophenones and xanthones from Hypericum scabrum. Journal of Natural Products. 67: 1870-5. PMID 15568778 DOI: 10.1021/Np040024+ |
0.417 |
|
| 2004 |
Wang X, Bastow KF, Sun CM, Lin YL, Yu HJ, Don MJ, Wu TS, Nakamura S, Lee KH. Antitumor Agents. 239. Isolation, structure elucidation, total synthesis, and anti-breast cancer activity of neo-tanshinlactone from Salvia miltiorrhiza. Journal of Medicinal Chemistry. 47: 5816-9. PMID 15509181 DOI: 10.1021/Jm040112R |
0.325 |
|
| 2004 |
Xiao Z, Bastow KF, Vance JR, Sidwell RS, Wang HK, Chen MS, Shi Q, Lee KH. Antitumor agents. 234. Design, synthesis, and biological evaluation of novel 4β-[(4″-benzamido)-amino]-4′-O-demethyl- epipodophyllotoxin derivatives Journal of Medicinal Chemistry. 47: 5140-5148. PMID 15456257 DOI: 10.1021/jm030609l |
0.474 |
|
| 2004 |
Murakami C, Fukamiya N, Tamura S, Okano M, Bastow KF, Tokuda H, Mukainaka T, Nishino H, Lee KH. Multidrug-resistant cancer cell susceptibility to cytotoxic quassinoids, and cancer chemopreventive effects of quassinoids and canthin alkaloids. Bioorganic & Medicinal Chemistry. 12: 4963-8. PMID 15336275 DOI: 10.1016/j.bmc.2004.06.045 |
0.444 |
|
| 2004 |
Tanaka N, Ooba N, Duan H, Takaishi Y, Nakanishi Y, Bastow K, Lee KH. Kaurane and abietane diterpenoids from Tripterygium doianum (Celastraceae). Phytochemistry. 65: 2071-6. PMID 15279974 DOI: 10.1016/J.Phytochem.2004.04.032 |
0.434 |
|
| 2004 |
Hayashi KI, Chang FR, Nakanishi Y, Bastow KF, Cragg G, McPhail AT, Nozaki H, Lee KH. Antitumor agents. 233.1 Lantalucratins A-F, new cytotoxic naphthoquinones from Lantana involucrata Journal of Natural Products. 67: 990-993. PMID 15217280 DOI: 10.1021/np030450f |
0.356 |
|
| 2004 |
Xiao Z, Vance JR, Bastow KF, Brossi A, Wang HK, Lee KH. Antitumor agents. Part 235: Novel 4′-ester etoposide analogues as potent DNA topoisomerase II inhibitors with improved therapeutic potential Bioorganic and Medicinal Chemistry. 12: 3363-3369. PMID 15158805 DOI: 10.1016/j.bmc.2004.03.056 |
0.488 |
|
| 2004 |
Xiao Z, Bastow KF, Vance JR, Lee KH. Antitumor agents. Part 227: Studies on novel 4′-O-demethyl- epipodophyllotoxins as antitumor agents targeting topoisomerase II Bioorganic and Medicinal Chemistry. 12: 3339-3344. PMID 15158802 DOI: 10.1016/j.bmc.2004.03.067 |
0.436 |
|
| 2004 |
Han S, Xiao Z, Bastow KF, Lee KH. Antitumor agents. Part 230: C4'-esters of GL-331 as cytotoxic agents and DNA topoisomerase II inhibitors. Bioorganic & Medicinal Chemistry Letters. 14: 2979-82. PMID 15125972 DOI: 10.1016/j.bmcl.2004.02.102 |
0.48 |
|
| 2004 |
Xiao Z, Han S, Bastow KF, Lee KH. Antitumor agents. Part 232: Synthesis of cyclosulfite podophyllotoxin analogues as novel prototype antitumor agents. Bioorganic & Medicinal Chemistry Letters. 14: 1581-4. PMID 15006408 DOI: 10.1016/j.bmcl.2003.12.096 |
0.476 |
|
| 2003 |
Chang FR, Hayashi KI, Chen IH, Liaw CC, Bastow KF, Nakanishi Y, Nozaki H, Cragg GM, Wu YC, Lee KH. Antitumor Agents. 228. Five New Agarofurans, Reissantins A-E, and Cytotoxic Principles from Reissantia buchananii Journal of Natural Products. 66: 1416-1420. PMID 14640511 DOI: 10.1021/Np030241V |
0.354 |
|
| 2003 |
Lowden CT, Bastow KF. Anti-herpes simplex virus activity of substituted 1-hydroxyacridones. Journal of Medicinal Chemistry. 46: 5015-20. PMID 14584951 DOI: 10.1021/Jm030206L |
0.712 |
|
| 2003 |
Lowden CT, Bastow KF. Cell culture replication of herpes simplex virus and, or human cytomegalovirus is inhibited by 3,7-dialkoxylated, 1-hydroxyacridone derivatives. Antiviral Research. 59: 143-54. PMID 12927304 DOI: 10.1016/S0166-3542(03)00106-2 |
0.738 |
|
| 2003 |
Nakanishi Y, Chang FR, Liaw CC, Wu YC, Bastow KF, Lee KH. Acetogenins as selective inhibitors of the human ovarian 1A9 tumor cell line. Journal of Medicinal Chemistry. 46: 3185-8. PMID 12852747 DOI: 10.1021/jm020548b |
0.322 |
|
| 2003 |
Wu JH, Chang FR, Hayashi Ki, Shiraki H, Liaw CC, Nakanishi Y, Bastow KF, Yu D, Chen IS, Lee KH. Antitumor agents. Part 218: Cappamensin A, a new In vitro anticancer principle, from Capparis sikkimensis. Bioorganic & Medicinal Chemistry Letters. 13: 2223-5. PMID 12798338 DOI: 10.1016/S0960-894X(03)00379-2 |
0.391 |
|
| 2003 |
Ohtsu H, Nakanishi Y, Bastow KF, Lee FY, Lee KH. Antitumor agents 216. Synthesis and evaluation of paclitaxel-camptothecin conjugates as novel cytotoxic agents. Bioorganic & Medicinal Chemistry. 11: 1851-7. PMID 12659771 DOI: 10.1016/S0968-0896(03)00040-3 |
0.568 |
|
| 2003 |
Oyama M, Bastow KF, Tachibana Y, Shirataki Y, Yamaguchi S, Cragg GM, Wu TS, Lee KH. Antitumor agents 225. Acrofoliones A and B, two novel cytotoxic acetophenone dimers, from Acronychia trifoliolata Chinese Pharmaceutical Journal. 55: 239-245. |
0.408 |
|
| 2002 |
Han S, Hamel E, Bastow KF, McPhail AT, Brossi A, Lee KH. Antitumor agents. Part 215: antitubulin effects of cytotoxic B-ring modified allocolchicinoids. Bioorganic & Medicinal Chemistry Letters. 12: 2851-3. PMID 12270161 DOI: 10.1016/S0960-894X(02)00635-2 |
0.415 |
|
| 2002 |
Shinozaki Y, Fukamiya N, Uchiyama C, Okano M, Tagahara K, Bastow KF, Lee KH. Multidrug resistant cancer cells susceptibility to cytotoxic taxane diterpenes from Taxus yunnanensis and Taxus chinensis. Bioorganic & Medicinal Chemistry Letters. 12: 2785-8. PMID 12217376 DOI: 10.1016/S0960-894X(02)00528-0 |
0.344 |
|
| 2002 |
Ishida J, Ohtsu H, Tachibana Y, Nakanishi Y, Bastow KF, Nagai M, Wang HK, Itokawa H, Lee KH. Antitumor agents. Part 214: synthesis and evaluation of curcumin analogues as cytotoxic agents. Bioorganic & Medicinal Chemistry. 10: 3481-7. PMID 12213462 DOI: 10.1016/S0968-0896(02)00249-3 |
0.376 |
|
| 2002 |
Wongsinkongman P, Brossi A, Wang HK, Bastow KF, Lee KH. Antitumor agents. Part 209: Pheophorbide-a derivatives as photo-Independent cytotoxic agents. Bioorganic & Medicinal Chemistry. 10: 583-91. PMID 11814846 DOI: 10.1016/S0968-0896(01)00305-4 |
0.66 |
|
| 2002 |
Hayashi KI, Nakanishi Y, Bastow KF, Cragg G, Nozaki H, Lee KH. Antitumor agents. Part 212: Bucidarasins A-C, three new cytotoxic clerodane diterpenes from Bucida buceras Bioorganic and Medicinal Chemistry Letters. 12: 345-348. PMID 11814793 DOI: 10.1016/S0960-894X(01)00742-9 |
0.383 |
|
| 2002 |
Akanitapichat P, Bastow KF. The antiviral agent 5-chloro-1,3-dihydroxyacridone interferes with assembly and maturation of herpes simplex virus Antiviral Research. 53: 113-126. PMID 11750937 DOI: 10.1016/S0166-3542(01)00203-0 |
0.371 |
|
| 2001 |
Shi Q, Wang HK, Bastow KF, Tachibana Y, Chen K, Lee FY, Lee KH. Antitumor agents 210. synthesis and evaluation of taxoid-epipodophyllotoxin conjugates as novel cytotoxic agents Bioorganic and Medicinal Chemistry. 9: 2999-3004. PMID 11597482 DOI: 10.1016/S0968-0896(01)00206-1 |
0.541 |
|
| 2001 |
Iwasa K, Moriyasu M, Tachibana Y, Kim HS, Wataya Y, Wiegrebe W, Bastow KF, Cosentino LM, Kozuka M, Lee KH. Simple isoquinoline and benzylisoquinoline alkaloids as potential antimicrobial, antimalarial, cytotoxic, and anti-HIV agents Bioorganic and Medicinal Chemistry. 9: 2871-2884. PMID 11597468 DOI: 10.1016/S0968-0896(01)00154-7 |
0.311 |
|
| 2001 |
Na Y, Li VS, Nakanishi Y, Bastow KF, Kohn H. Synthesis, DNA cross-linking activity, and cytotoxicity of dimeric mitomycins. Journal of Medicinal Chemistry. 44: 3453-62. PMID 11585450 DOI: 10.1021/Jm010090Y |
0.314 |
|
| 2001 |
Cheng HH, Wang HK, Ito J, Bastow KF, Tachibana Y, Nakanishi Y, Xu Z, Luo TY, Lee KH. Cytotoxic pheophorbide-related compounds from Clerodendrum calamitosum and C. cyrtophyllum Journal of Natural Products. 64: 915-919. PMID 11473423 DOI: 10.1021/Np000595B |
0.361 |
|
| 2001 |
Mishra L, Sinha R, Itokawa H, Bastow KF, Tachibana Y, Nakanishi Y, Kilgore N, Lee KH. Anti-HIV and cytotoxic activities of Ru(II)/Ru(III) polypyridyl complexes containing 2,6-(2′-benzimidazolyl)-pyridine/chalcone as co-ligand Bioorganic and Medicinal Chemistry. 9: 1667-1671. PMID 11425566 DOI: 10.1016/S0968-0896(01)00074-8 |
0.343 |
|
| 2001 |
Xia Y, Yang ZY, Hour MJ, Kuo SC, Xia P, Bastow KF, Nakanishi Y, Nampoothiri P, Hackl T, Hamel E, Lee KH. Antitumor agents. Part 204: Synthesis and biological evaluation of substituted 2-aryl quinazolinones Bioorganic and Medicinal Chemistry Letters. 11: 1193-1196. PMID 11354375 DOI: 10.1016/S0960-894X(01)00190-1 |
0.473 |
|
| 2001 |
Krishnan P, Bastow KF. Novel mechanism of cellular DNA topoisomerase II inhibition by the pyranonaphthoquinone derivatives alpha-lapachone and beta-lapachone. Cancer Chemotherapy and Pharmacology. 47: 187-98. PMID 11320661 DOI: 10.1007/S002800000221 |
0.512 |
|
| 2001 |
VanVliet DS, Tachibana Y, Bastow KF, Huang ES, Lee KH. Antitumor agents. 207. Design, synthesis, and biological testing of 4β-anilino-2-fluoro-4′-demethylpodophyllotoxin analogues as cytotoxic and antiviral agents Journal of Medicinal Chemistry. 44: 1422-1428. PMID 11311065 DOI: 10.1021/Jm000377F |
0.492 |
|
| 2000 |
Krishnan P, Bastow KF. The 9-position in berberine analogs is an important determinant of DNA topoisomerase II inhibition. Anti-Cancer Drug Design. 15: 255-64. PMID 11200501 |
0.619 |
|
| 2000 |
Xu Z, Chang FR, Wang HK, Kashiwada Y, McPhail AT, Bastow KF, Tachibana Y, Cosentino M, Lee KH. Anti-HIV agents 451 and antitumor agents 205.2 Two new sesquiterpenes, leitneridanins A and B, and the cytotoxic and anti-HIV principles from Leitneria floridana Journal of Natural Products. 63: 1712-1715. PMID 11141127 DOI: 10.1021/Np000260U |
0.353 |
|
| 2000 |
Hour MJ, Huang LJ, Kuo SC, Xia Y, Bastow K, Nakanishi Y, Hamel E, Lee KH. 6-alkylamino- and 2,3-dihydro-3′-methoxy-2-phenyl-4-quinazolinones and related compounds: Their synthesis, cytotoxicity, and inhibition of tubulin polymerization Journal of Medicinal Chemistry. 43: 4479-4487. PMID 11087572 DOI: 10.1021/Jm000151C |
0.558 |
|
| 2000 |
Krishnan P, Bastow KF. Novel mechanisms of DNA topoisomerase II inhibition by pyranonaphthoquinone derivatives-eleutherin, alpha lapachone, and beta lapachone. Biochemical Pharmacology. 60: 1367-79. PMID 11008131 DOI: 10.1016/S0006-2952(00)00437-8 |
0.642 |
|
| 2000 |
Itoigawa M, Kashiwada Y, Ito C, Furukawa H, Tachibana Y, Bastow KF, Lee KH. Antitumor agents. 203. Carbazole alkaloid murrayaquinone A and related synthetic carbazolequinones as cytotoxic agent Journal of Natural Products. 63: 896-897. PMID 10924160 |
0.422 |
|
| 2000 |
Akanitapichat P, Lowden CT, Bastow KF. 1,3-Dihydroxyacridone derivatives as inhibitors of herpes virus replication. Antiviral Research. 45: 123-34. PMID 10809021 DOI: 10.1016/S0166-3542(00)00068-1 |
0.733 |
|
| 2000 |
Xia Y, Yang ZY, Xia P, Bastow KF, Nakanishi Y, Lee KH. Antitumor agents. Part 202: Novel 2'-amino chalcones: Design, synthesis and biological evaluation Bioorganic and Medicinal Chemistry Letters. 10: 699-701. PMID 10782667 DOI: 10.1016/S0960-894X(00)00072-X |
0.414 |
|
| 2000 |
Tachibana Y, Zhu XK, Krishnan P, Lee KH, Bastow KF. Characterization of human lung cancer cells resistant to 4'-O-demethyl-4beta-(2"-nitro-4"-fluoroanilino)-4-desoxypodophyllotoxin , a unique compound in the epipodophyllotoxin antitumor class. Anti-Cancer Drugs. 11: 19-28. PMID 10757559 DOI: 10.1097/00001813-200001000-00004 |
0.622 |
|
| 2000 |
Chang JY, Guo X, Chen HX, Jiang Z, Fu Q, Wang HK, Bastow KF, Zhu XK, Guan J, Lee KH, Cheng YC. Unique biochemical, cytotoxic, and antitumor activity of camptothecin and 4β-amino-4'-O-demethylepipodophyllotoxin conjugates Biochemical Pharmacology. 59: 497-508. PMID 10660116 DOI: 10.1016/S0006-2952(99)00363-9 |
0.362 |
|
| 1999 |
Ohyama M, Tanaka T, Ito T, Iinuma M, Bastow KF, Lee KH. Antitumor agents 200. Cytotoxicity of naturally occurring resveratrol oligomers and their acetate derivatives Bioorganic and Medicinal Chemistry Letters. 9: 3057-3060. PMID 10571175 DOI: 10.1016/S0960-894X(99)00520-X |
0.398 |
|
| 1999 |
Zhang SX, Bastow KF, Tachibana Y, Kuo SC, Hamel E, Mauger A, Narayanan VL, Lee KH. Antitumor agents. 196. Substituted 2-thienyl-1,8-naphthyridin-4-ones: Their synthesis, cytotoxicity, and inhibition of tubulin polymerization Journal of Medicinal Chemistry. 42: 4081-4087. PMID 10514278 DOI: 10.1021/jm990208z |
0.503 |
|
| 1999 |
Vance JR, Bastow KF. Inhibition of DNA topoisomerase II catalytic activity by the antiviral agents 7-chloro-1,3-dihydroxyacridone and 1,3,7-trihydroxyacridone Biochemical Pharmacology. 58: 703-708. PMID 10413309 DOI: 10.1016/S0006-2952(99)00140-9 |
0.489 |
|
| 1999 |
Zhu XK, Guan J, Tachibana Y, Bastow KF, Sung Jin Cho, Cheng H.- H, Cheng YC, Gurwith M, Lee KH. Antitumor agents. 194. Synthesis and biological evaluations of 4-β- mono-, -di-, and -trisubstituted aniline-4'-O-demethyl-podophyllotoxin and related compounds with improved pharmacological profiles Journal of Medicinal Chemistry. 42: 2441-2446. PMID 10395485 DOI: 10.1021/Jm990055F |
0.4 |
|
| 1999 |
Yang ZY, Xia Y, Xia P, Tachibana Y, Bastow KF, Lee KH. Antitumor agents 187: Synthesis and cytotoxicity of substituted 8,8- dimethyl-2H,8H-pyrano[6,5-h]quinoline-2-one and related compounds Bioorganic and Medicinal Chemistry Letters. 9: 713-716. PMID 10201834 DOI: 10.1016/S0960-894X(99)00065-7 |
0.348 |
|
| 1999 |
Guan J, Zhu XK, Brossi A, Tachibana Y, Bastow KF, Verdier-Pinard P, Hamel E, McPhail AT, Lee KH. Antitumor agents. 192. Antitubulin effect and cytotoxicity of C(7)-oxygenated allocolchicinoids Collection of Czechoslovak Chemical Communications. 64: 217-228. |
0.435 |
|
| 1998 |
Guan J, Zhu XK, Tachibana Y, Bastow KF, Brossi A, Hamel E, Lee KH. Antitumor agents. Part 186: Synthesis and biological evaluation of demethylcolchiceinamide analogues as cytotoxic DNA topoisomerase II inhibitors Bioorganic and Medicinal Chemistry. 6: 2127-2131. PMID 9881102 DOI: 10.1016/S0968-0896(98)00165-5 |
0.44 |
|
| 1998 |
Miller MC, Bastow KF, Stineman CN, Vance JR, Song SC, West DX, Hall IH. The cytotoxicity of 2-formyl and 2-acetyl-(6-picolyl)-4N-substituted thiosemicarbazones and their copper(II) complexes Archiv Der Pharmazie. 331: 121-127. PMID 9648520 DOI: 10.1002/(Sici)1521-4184(199804)331:4<121::Aid-Ardp121>3.0.Co;2-T |
0.409 |
|
| 1998 |
Guan J, Zhu XK, Tachibana Y, Bastow KF, Brossi A, Hamel E, Lee KH. Antitumor agents. 185. Synthesis and biological evaluation of tridemethylthiocolchicine analogues as novel topoisomerase II inhibitors Journal of Medicinal Chemistry. 41: 1956-1961. PMID 9599244 DOI: 10.1021/Jm980007F |
0.479 |
|
| 1998 |
Xia Y, Yang ZY, Xia P, Bastow KF, Tachibana Y, Kuo SC, Hamel E, Hackl T, Lee KH. Antitumor agents. 181. Synthesis and biological evaluation of 6,7,2',3',4'-substituted-1,2,3,4-tetrahydro-2-phenyl-4-quinolones as a new class of antimitotic antitumor agents Journal of Medicinal Chemistry. 41: 1155-1162. PMID 9544215 DOI: 10.1021/jm9707479 |
0.431 |
|
| 1997 |
Bastow KF, Wang HK, Cheng YC, Lee KH. Antitumor Agents-CLXXIII. Synthesis and evaluation of camptothecin-4β-amino-4'-O-demethyl epipodophyllotoxin conjugates as inhibitors of mammalian DNA topoisomerases and as cytotoxic agents Bioorganic and Medicinal Chemistry. 5: 1481-1488. PMID 9313854 DOI: 10.1016/S0968-0896(97)00102-8 |
0.502 |
|
| 1997 |
Miller MC, Sood A, Spielvogel BF, Bastow K, Hall IH. Cytotoxic action of carboxyborane heterocyclic amine adducts Metal-Based Drugs. 4: 229-241. DOI: 10.1155/Mbd.1997.229 |
0.405 |
|
| 1997 |
Ji Z, Wang HK, Bastow KF, Zhu XK, Cho SJ, Cheng YC, Lee KH. Antitumor agents. 177. Design, syntheses, and biological evaluation of novel etoposide analogs bearing pyrrolecarboxamidino group as DNA topoisomerase II inhibitors Bioorganic and Medicinal Chemistry Letters. 7: 607-612. DOI: 10.1016/S0960-894X(97)00060-7 |
0.467 |
|
| 1996 |
Chen X, Bastow K, Goz B, Kucera LS, Morris-Natschke SL, Ishaq KS. Synthesis and evaluation of novel thymidine analogs as antitumor and antiviral agents Journal of Medicinal Chemistry. 39: 3412-3417. PMID 8765526 DOI: 10.1021/Jm9601260 |
0.537 |
|
| 1996 |
Cho SJ, Kashiwada Y, Bastow KF, Cheng YC, Lee KH. Antitumor agents. 164. Podophenazine, 2″,3″-dichloropodophenazine, benzopodophenazine, and their 4β-p-nitroaniline derivatives as novel DNA topoisomerase II inhibitors Journal of Medicinal Chemistry. 39: 1396-1402. PMID 8691469 |
0.344 |
|
| 1996 |
Wang HK, Bastow KF, Cosentino LM, Lee KH. Antitumor agents. 166. Synthesis and biological evaluation of 5,6,7,8-substituted-2-phenylthiochromen-4-ones Journal of Medicinal Chemistry. 39: 1975-1980. PMID 8642556 DOI: 10.1021/jm960008c |
0.548 |
|
| 1996 |
Chen X, Bastow K, Goz B, Kucera L, Morris-Natschke SL, Ishaq KS. Boronic acid derivatives targeting HIV-1 Antiviral Chemistry and Chemotherapy. 7: 108-114. DOI: 10.1177/095632029600700208 |
0.397 |
|
| 1995 |
Kitanaka S, Yasuda I, Kashiwada Y, Hu CQ, Bastow KF, Bori ID, Lee KH. Antitumor agents, 162. Cell-based assays for identifying novel DNA topoisomerase inhibitors: Studies on the constituents of Fatsia japonica Journal of Natural Products. 58: 1647-1654. PMID 8594141 |
0.402 |
|
| 1995 |
Fukushima Y, Bastow KF, Ohba T, Lee KH. Antiviral activity of dammarane saponins against herpes simplex virus I International Journal of Pharmacognosy. 33: 2-6. DOI: 10.3109/13880209509088139 |
0.389 |
|
| 1995 |
Kashiwada Y, Bastow KF, Lee KH. Novel lignan derivatives as selective inhibitors of DNA topoisomerase II Bioorganic and Medicinal Chemistry Letters. 5: 905-908. DOI: 10.1016/0960-894X(95)00138-J |
0.4 |
|
| 1994 |
Sood A, Spielvogel BF, Powell WJ, Bastow KF, Miller MC, Hall IH. Cytotoxicity of ribo - and arabinoside boron nucleosides in tissue culture cells Anticancer Research. 14: 1483-1488. PMID 7979174 |
0.406 |
|
| 1994 |
Bastow KF, Itoigawa M, Furukawa H, Kashiwada Y, Bori ID, Ballas LM, Lee KH. Antiproliferative actions of 7-substituted 1,3-dihydroxyacridones; possible involvement of DNA topoisomerase II and protein kinase C as biochemical targets Bioorganic and Medicinal Chemistry. 2: 1403-1411. PMID 7788303 DOI: 10.1016/S0968-0896(00)82092-1 |
0.446 |
|
| 1993 |
Kashiwada Y, Nonaka G‐, Nishioka I, Lee KJ, Bori I, Fukushima Y, Bastow KF, Lee K‐. Tannins as potent inhibitors of DNA topoisomerase II in vitro Journal of Pharmaceutical Sciences. 82: 487-492. PMID 8395599 DOI: 10.1002/jps.2600820511 |
0.5 |
|
| 1993 |
Bastow KF, Bori ID, Fukushima Y, Kashiwada Y, Tanaka T, Nonaka G, Nishioka I, Lee KH. Inhibition of DNA topoisomerases by sanguiin H-6, a cytotoxic dimeric ellagitannin from Sanguisorba officinalis Planta Medica. 59: 240-245. PMID 8391144 |
0.387 |
|
| 1993 |
Bastow KF, Tatematsu H, Sun L, Fukushima Y, Lee KH. Synthesis and biological evaluation of tetrademethyl isocolchicine derivatives as inhibitors of DNA topoisomerase action in vitro Bioorganic and Medicinal Chemistry. 1: 227-234. PMID 8081856 DOI: 10.1016/S0968-0896(00)82125-2 |
0.409 |
|
| 1993 |
Bastow KF, Tatematsu H, Bori ID, Fukushima Y, Sun L, Goz B, Lee KH. Induction of reversible protein-linked DNA breaks in human osteogenic sarcoma cells by novel cytocidal colchicine derivatives which inhibit DNA topoisomerase II in vitro: Absence of cross-resistance in a colchicine-resistant sub-clone Bioorganic and Medicinal Chemistry Letters. 3: 1045-1050. DOI: 10.1016/S0960-894X(00)80284-X |
0.34 |
|
| 1985 |
Cheng YC, Grill SP, Dutschman GE, Frank KB, Chiou JF, Bastow KF, Nakayama K. Effects of 9-(1,3-dihydroxy-2-propoxymethyl)guanine, a new antiherpesvirus compound, on synthesis of macromolecules in herpes simplex virus-infected cells. Antimicrobial Agents and Chemotherapy. 26: 283-8. PMID 6095751 DOI: 10.1128/AAC.26.3.283 |
0.387 |
|
| 1984 |
Frank KB, Derse DD, Bastow KF, Cheng YC. Novel interaction of aphidicolin with herpes simplex virus DNA polymerase and polymerase-associated exonuclease Journal of Biological Chemistry. 259: 13282-13286. PMID 6092371 |
0.331 |
|
| 1983 |
Cheng YC, Grill SP, Dutschman GE, Nakayama K, Bastow KF. Metabolism of 9-(1,3-dihydroxy-2-propoxymethyl)guanine, a new anti-herpes virus compound, in herpes simplex virus-infected cells Journal of Biological Chemistry. 258: 12460-12464. PMID 6313660 |
0.374 |
|
| 1980 |
Bastow KF, Darby G, Wildy P, Minson AC. Properties of cells carrying the herpes simplex virus type 2 thymidine kinase gene: Mechanisms of reversion to a thymidine kinase-negative phenotype Journal of Virology. 36: 746-755. |
0.317 |
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