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Christopher D. Wiley, Ph.D. - Publications

Affiliations: 
2002-2008 University of California, Irvine, Irvine, CA 
 2008-2020 Buck Institute for Research on Aging 
 2020- Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, MA, United States 
Area:
Genetics, Anatomy Biology, Molecular Biology
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Mogck BA, Jezak ST, Wiley CD. Mitochondria-Targeted Catalase Does Not Suppress Development of Cellular Senescence during Aging. Biomedicines. 12. PMID 38398016 DOI: 10.3390/biomedicines12020414  0.317
2023 Kuehnemann C, Wiley CD. Senescent cells at the crossroads of aging, disease, and tissue homeostasis. Aging Cell. e13988. PMID 37731189 DOI: 10.1111/acel.13988  0.327
2023 Faggioli F, Velarde MC, Wiley CD. Cellular Senescence, a Novel Area of Investigation for Metastatic Diseases. Cells. 12. PMID 36980201 DOI: 10.3390/cells12060860  0.637
2022 Kuehnemann C, Hughes JB, Desprez PY, Melov S, Wiley CD, Campisi J. Antiretroviral protease inhibitors induce features of cellular senescence that are reversible upon drug removal. Aging Cell. e13750. PMID 36539941 DOI: 10.1111/acel.13750  0.463
2021 Wiley CD, Campisi J. The metabolic roots of senescence: mechanisms and opportunities for intervention. Nature Metabolism. 3: 1290-1301. PMID 34663974 DOI: 10.1038/s42255-021-00483-8  0.475
2021 Wiley CD, Sharma R, Davis SS, Lopez-Dominguez JA, Mitchell KP, Wiley S, Alimirah F, Kim DE, Payne T, Rosko A, Aimontche E, Deshpande SM, Neri F, Kuehnemann C, Demaria M, et al. Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis. Cell Metabolism. PMID 33811820 DOI: 10.1016/j.cmet.2021.03.008  0.505
2020 Covarrubias AJ, Kale A, Perrone R, Lopez-Dominguez JA, Pisco AO, Kasler HG, Schmidt MS, Heckenbach I, Kwok R, Wiley CD, Wong HS, Gibbs E, Iyer SS, Basisty N, Wu Q, et al. Author Correction: Senescent cells promote tissue NAD decline during ageing via the activation of CD38 macrophages. Nature Metabolism. PMID 33303985 DOI: 10.1038/s42255-020-00328-w  0.459
2020 Covarrubias AJ, Kale A, Perrone R, Lopez-Dominguez JA, Pisco AO, Kasler HG, Schmidt MS, Heckenbach I, Kwok R, Wiley CD, Wong HS, Gibbs E, Iyer SS, Basisty N, Wu Q, et al. Senescent cells promote tissue NAD decline during ageing via the activation of CD38 macrophages. Nature Metabolism. 2: 1265-1283. PMID 33199924 DOI: 10.1038/s42255-020-00305-3  0.476
2020 Alimirah F, Pulido T, Valdovinos A, Alptekin S, Chang E, Jones E, Diaz DA, Flores J, Velarde MC, Demaria M, Davalos AR, Wiley CD, Limbad C, Desprez PY, Campisi J. Cellular senescence promotes skin carcinogenesis through p38MAPK and p44/p42MAPK signaling. Cancer Research. PMID 32641409 DOI: 10.1158/0008-5472.CAN-20-0108  0.679
2019 Kim DE, Dollé MET, Vermeij WP, Gyenis A, Vogel K, Hoeijmakers JHJ, Wiley CD, Davalos AR, Hasty P, Desprez PY, Campisi J. Deficiency in the DNA repair protein ERCC1 triggers a link between senescence and apoptosis in human fibroblasts and mouse skin. Aging Cell. e13072. PMID 31737985 DOI: 10.1111/Acel.13072  0.556
2019 Wiley CD, Brumwell AN, Davis SS, Jackson JR, Valdovinos A, Calhoun C, Alimirah F, Castellanos CA, Ruan R, Wei Y, Chapman HA, Ramanathan A, Campisi J, Jourdan Le Saux C. Secretion of leukotrienes by senescent lung fibroblasts promotes pulmonary fibrosis. Jci Insight. PMID 31687975 DOI: 10.1172/Jci.Insight.130056  0.483
2019 Wiley CD, Liu S, Limbad C, Zawadzka AM, Beck J, Demaria M, Artwood R, Alimirah F, Lopez-Dominguez JA, Kuehnemann C, Danielson SR, Basisty N, Kasler HG, Oron TR, Desprez PY, et al. SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells. Cell Reports. 28: 3329-3337.e5. PMID 31553904 DOI: 10.1016/J.Celrep.2019.08.049  0.544
2019 Patil P, Dong Q, Wang D, Chang J, Wiley C, Demaria M, Lee J, Kang J, Niedernhofer LJ, Robbins PD, Sowa G, Campisi J, Zhou D, Vo N. Systemic clearance of p16 -positive senescent cells mitigates age-associated intervertebral disc degeneration. Aging Cell. e12927. PMID 30900385 DOI: 10.1111/Acel.12927  0.504
2018 Wiley CD, Schaum N, Alimirah F, Lopez-Dominguez JA, Orjalo AV, Scott G, Desprez PY, Benz C, Davalos AR, Campisi J. Small-molecule MDM2 antagonists attenuate the senescence-associated secretory phenotype. Scientific Reports. 8: 2410. PMID 29402901 DOI: 10.1038/S41598-018-20000-4  0.537
2017 Wiley CD, Flynn JM, Morrissey C, Lebofsky R, Shuga J, Dong X, Unger MA, Vijg J, Melov S, Campisi J. Analysis of individual cells identifies cell-to-cell variability following induction of cellular senescence. Aging Cell. PMID 28699239 DOI: 10.1111/Acel.12632  0.537
2017 Perrott KM, Wiley CD, Desprez PY, Campisi J. Apigenin suppresses the senescence-associated secretory phenotype and paracrine effects on breast cancer cells. Geroscience. PMID 28378188 DOI: 10.1007/s11357-017-9970-1  0.539
2016 Hodes RJ, Sierra F, Austad SN, Epel E, Neigh GN, Erlandson KM, Schafer MJ, LeBrasseur NK, Wiley C, Campisi J, Sehl ME, Scalia R, Eguchi S, Kasinath BS, Halter JB, et al. Disease drivers of aging. Annals of the New York Academy of Sciences. 1386: 45-68. PMID 27943360 DOI: 10.1111/Nyas.13299  0.446
2016 Wiley CD, Campisi J. From Ancient Pathways to Aging Cells-Connecting Metabolism and Cellular Senescence. Cell Metabolism. 23: 1013-21. PMID 27304503 DOI: 10.1016/j.cmet.2016.05.010  0.54
2016 Lecot P, Alimirah F, Desprez PY, Campisi J, Wiley C. Context-dependent effects of cellular senescence in cancer development. British Journal of Cancer. PMID 27140310 DOI: 10.1038/bjc.2016.115  0.533
2015 Wiley CD, Velarde MC, Lecot P, Liu S, Sarnoski EA, Freund A, Shirakawa K, Lim HW, Davis SS, Ramanathan A, Gerencser AA, Verdin E, Campisi J. Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype. Cell Metabolism. PMID 26686024 DOI: 10.1016/J.Cmet.2015.11.011  0.692
2015 Ziegler DV, Wiley CD, Velarde MC. Mitochondrial effectors of cellular senescence: beyond the free radical theory of aging. Aging Cell. 14: 1-7. PMID 25399755 DOI: 10.1111/Acel.12287  0.631
2014 Vrana PB, Shorter KR, Szalai G, Felder MR, Crossland JP, Veres M, Allen JE, Wiley CD, Duselis AR, Dewey MJ, Dawson WD. Peromyscus (deer mice) as developmental models. Wiley Interdisciplinary Reviews. Developmental Biology. 3: 211-30. PMID 24896658 DOI: 10.1002/Wdev.132  0.662
2014 Wiley C, Campisi J. NAD+ controls neural stem cell fate in the aging brain. The Embo Journal. 33: 1289-91. PMID 24894550 DOI: 10.15252/embj.201488969  0.44
2009 Kingsley EP, Manceau M, Wiley CD, Hoekstra HE. Melanism in peromyscus is caused by independent mutations in agouti. Plos One. 4: e6435. PMID 19649329 DOI: 10.1371/Journal.Pone.0006435  0.318
2008 Oriel RC, Wiley CD, Dewey MJ, Vrana PB. Adaptive genetic variation, stress and glucose regulation. Disease Models & Mechanisms. 1: 255-63. PMID 19093033 DOI: 10.1242/Dmm.000661  0.66
2008 Wiley CD, Matundan HH, Duselis AR, Isaacs AT, Vrana PB. Patterns of hybrid loss of imprinting reveal tissue- and cluster-specific regulation. Plos One. 3: e3572. PMID 18958286 DOI: 10.1371/Journal.Pone.0003572  0.673
2008 Pan Z, Sikandar S, Witherspoon M, Dizon D, Nguyen T, Benirschke K, Wiley C, Vrana P, Lipkin SM. Impaired placental trophoblast lineage differentiation in Alkbh1(-/-) mice. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 316-27. PMID 18163532 DOI: 10.1002/Dvdy.21418  0.661
2005 Duselis AR, Wiley CD, O'Neill MJ, Vrana PB. Genetic evidence for a maternal effect locus controlling genomic imprinting and growth. Genesis (New York, N.Y. : 2000). 43: 155-65. PMID 16283622 DOI: 10.1002/Gene.20166  0.671
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