Steven Estus - Publications

Affiliations: 
University of Kentucky, Lexington, KY 
Area:
Neuroscience Biology, Molecular Biology, Cell Biology

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Turner AK, Shaw BC, Simpson JF, Estus S. Identification and Quantitation of Novel Isoforms Relative to Alzheimer's Disease Genetics and Neuropathology. Genes. 13. PMID 36140776 DOI: 10.3390/genes13091607  0.33
2020 Parikh IJ, Estus JL, Zajac DJ, Malik M, Maldonado Weng J, Tai LM, Chlipala GE, LaDu MJ, Green SJ, Estus S. Murine Gut Microbiome Association With Alleles. Frontiers in Immunology. 11: 200. PMID 32117315 DOI: 10.3389/Fimmu.2020.00200  0.404
2019 Maldonado Weng J, Parikh I, Naqib A, York J, Green SJ, Estus S, LaDu MJ. Synergistic effects of APOE and sex on the gut microbiome of young EFAD transgenic mice. Molecular Neurodegeneration. 14: 47. PMID 31861986 DOI: 10.1186/S13024-019-0352-2  0.392
2019 Katsumata Y, Fardo DW, Bachstetter AD, Artiushin SC, Wang WX, Wei A, Brzezinski LJ, Nelson BG, Huang Q, Abner EL, Anderson S, Patel I, Shaw BC, Price DA, Niedowicz DM, ... ... Estus S, et al. Alzheimer Disease Pathology-Associated Polymorphism in a Complex Variable Number of Tandem Repeat Region Within the MUC6 Gene, Near the AP2A2 Gene. Journal of Neuropathology and Experimental Neurology. PMID 31748784 DOI: 10.1093/Jnen/Nlz116  0.371
2019 Estus S, Shaw BC, Devanney N, Katsumata Y, Press EE, Fardo DW. Evaluation of CD33 as a genetic risk factor for Alzheimer's disease. Acta Neuropathologica. PMID 30949760 DOI: 10.1007/S00401-019-02000-4  0.336
2018 Katsumata Y, Nelson PT, Estus S, Fardo DW. Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs. Neurobiology of Aging. 74: 135-146. PMID 30448613 DOI: 10.1016/J.Neurobiolaging.2018.10.017  0.43
2018 Koren S, Meier SE, Nation GK, Chishti E, Blalock E, Zhu H, Estus S, Abisambra JF. P4-265: Tau Modifies Ribosomal Dynamics Shifting Translational Profiles In Ad Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.07.087  0.322
2017 Vasquez JB, Simpson JF, Harpole R, Estus S. Alzheimer's Disease Genetics and ABCA7 Splicing. Journal of Alzheimer's Disease : Jad. PMID 28655137 DOI: 10.3233/Jad-170872  0.437
2016 De Rossi P, Buggia-Prévot V, Clayton BL, Vasquez JB, van Sanford C, Andrew RJ, Lesnick R, Botté A, Deyts C, Salem S, Rao E, Rice RC, Parent A, Kar S, Popko B, ... ... Estus S, et al. Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts. Molecular Neurodegeneration. 11: 59. PMID 27488240 DOI: 10.1186/S13024-016-0124-1  0.409
2016 Kang SS, Kurti A, Wojtas A, Baker KE, Liu CC, Kanekiyo T, Deming Y, Cruchaga C, Estus S, Bu G, Fryer JD. Identification of Plexin A4 as a novel Clusterin receptor links two Alzheimer's disease risk genes. Human Molecular Genetics. PMID 27378688 DOI: 10.1093/Hmg/Ddw188  0.381
2015 Malik M, Parikh I, Vasquez JB, Smith C, Tai L, Bu G, LaDu MJ, Fardo DW, Rebeck GW, Estus S. Genetics ignite focus on microglial inflammation in Alzheimer's disease. Molecular Neurodegeneration. 10: 52. PMID 26438529 DOI: 10.1186/S13024-015-0048-1  0.376
2015 Malik M, Chiles J, Xi HS, Medway C, Simpson J, Potluri S, Howard D, Liang Y, Paumi CM, Mukherjee S, Crane P, Younkin S, Fardo DW, Estus S. Genetics of CD33 in Alzheimer's disease and acute myeloid leukemia. Human Molecular Genetics. 24: 3557-70. PMID 25762156 DOI: 10.1093/Hmg/Ddv092  0.331
2015 Chester DS, DeWall CN, Derefinko KJ, Estus S, Peters JR, Lynam DR, Jiang Y. Monoamine oxidase A (MAOA) genotype predicts greater aggression through impulsive reactivity to negative affect. Behavioural Brain Research. 283: 97-101. PMID 25637908 DOI: 10.1016/J.Bbr.2015.01.034  0.3
2014 Liu CC, Tsai CW, Deak F, Rogers J, Penuliar M, Sung YM, Maher JN, Fu Y, Li X, Xu H, Estus S, Hoe HS, Fryer JD, Kanekiyo T, Bu G. Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease. Neuron. 84: 63-77. PMID 25242217 DOI: 10.1016/J.Neuron.2014.08.048  0.42
2014 Parikh I, Medway C, Younkin S, Fardo DW, Estus S. An intronic PICALM polymorphism, rs588076, is associated with allelic expression of a PICALM isoform. Molecular Neurodegeneration. 9: 32. PMID 25169757 DOI: 10.1186/1750-1326-9-32  0.421
2014 Gold BT, Zhu Z, Brown CA, Andersen AH, LaDu MJ, Tai L, Jicha GA, Kryscio RJ, Estus S, Nelson PT, Scheff SW, Abner E, Schmitt FA, Van Eldik LJ, Smith CD. White matter integrity is associated with cerebrospinal fluid markers of Alzheimer's disease in normal adults. Neurobiology of Aging. 35: 2263-71. PMID 24866404 DOI: 10.1016/J.Neurobiolaging.2014.04.030  0.309
2014 Nelson PT, Estus S, Abner EL, Parikh I, Malik M, Neltner JH, Ighodaro E, Wang WX, Wilfred BR, Wang LS, Kukull WA, Nandakumar K, Farman ML, Poon WW, Corrada MM, et al. ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology. Acta Neuropathologica. 127: 825-43. PMID 24770881 DOI: 10.1007/S00401-014-1282-2  0.364
2014 Parikh I, Fardo DW, Estus S. Genetics of PICALM expression and Alzheimer's disease. Plos One. 9: e91242. PMID 24618820 DOI: 10.1371/Journal.Pone.0091242  0.447
2014 Tai LM, Mehra S, Shete V, Estus S, Rebeck GW, Bu G, LaDu MJ. Soluble apoE/Aβ complex: mechanism and therapeutic target for APOE4-induced AD risk. Molecular Neurodegeneration. 9: 2. PMID 24386905 DOI: 10.1186/1750-1326-9-2  0.412
2013 Vasquez JB, Fardo DW, Estus S. ABCA7 expression is associated with Alzheimer's disease polymorphism and disease status. Neuroscience Letters. 556: 58-62. PMID 24141082 DOI: 10.1016/J.Neulet.2013.09.058  0.455
2013 Malik M, Simpson JF, Parikh I, Wilfred BR, Fardo DW, Nelson PT, Estus S. CD33 Alzheimer's risk-altering polymorphism, CD33 expression, and exon 2 splicing. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13320-5. PMID 23946390 DOI: 10.1523/Jneurosci.1224-13.2013  0.361
2013 Nelson PT, Pious NM, Jicha GA, Wilcock DM, Fardo DW, Estus S, Rebeck GW. APOE-ε2 and APOE-ε4 correlate with increased amyloid accumulation in cerebral vasculature. Journal of Neuropathology and Experimental Neurology. 72: 708-15. PMID 23771217 DOI: 10.1097/Nen.0B013E31829A25B9  0.345
2012 Ling IF, Bhongsatiern J, Simpson JF, Fardo DW, Estus S. Genetics of clusterin isoform expression and Alzheimer's disease risk. Plos One. 7: e33923. PMID 22506010 DOI: 10.1371/Journal.Pone.0033923  0.468
2012 Holler CJ, Webb RL, Laux AL, Beckett TL, Niedowicz DM, Ahmed RR, Liu Y, Simmons CR, Dowling AL, Spinelli A, Khurgel M, Estus S, Head E, Hersh LB, Murphy MP. BACE2 expression increases in human neurodegenerative disease. The American Journal of Pathology. 180: 337-50. PMID 22074738 DOI: 10.1016/J.Ajpath.2011.09.034  0.422
2012 Estus S. Elucidating the mechanisms underlying Alzheimer's disease-associated genetic polymorphisms Molecular Neurodegeneration. 7: L12. DOI: 10.1186/1750-1326-7-S1-L12  0.459
2011 Simmons CR, Zou F, Younkin SG, Estus S. Evaluation of the global association between cholesterol-associated polymorphisms and Alzheimer's disease suggests a role for rs3846662 and HMGCR splicing in disease risk. Molecular Neurodegeneration. 6: 62. PMID 21867541 DOI: 10.1186/1750-1326-6-62  0.446
2011 Simmons CR, Zou F, Younkin SG, Estus S. Rheumatoid arthritis-associated polymorphisms are not protective against Alzheimer's disease. Molecular Neurodegeneration. 6: 33. PMID 21595938 DOI: 10.1186/1750-1326-6-33  0.422
2010 Dieter LS, Estus S. Isoform of APOE with retained intron 3; quantitation and identification of an associated single nucleotide polymorphism. Molecular Neurodegeneration. 5: 34. PMID 20822524 DOI: 10.1186/1750-1326-5-34  0.393
2010 Ling IF, Gopalraj RK, Simpson JF, Estus S. Expression and regulation of a low-density lipoprotein receptor exon 12 splice variant. Journal of Neurochemistry. 115: 614-24. PMID 20807319 DOI: 10.1111/J.1471-4159.2010.06972.X  0.757
2010 Ling IF, Estus S. Role of SFRS13A in low-density lipoprotein receptor splicing. Human Mutation. 31: 702-9. PMID 20232416 DOI: 10.1002/Humu.21244  0.428
2009 Grear KE, Ling IF, Simpson JF, Furman JL, Simmons CR, Peterson SL, Schmitt FA, Markesbery WR, Liu Q, Crook JE, Younkin SG, Bu G, Estus S. Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain. Molecular Neurodegeneration. 4: 46. PMID 19889229 DOI: 10.1186/1750-1326-4-46  0.439
2009 Liu Q, Zhang J, Tran H, Verbeek MM, Reiss K, Estus S, Bu G. LRP1 shedding in human brain: roles of ADAM10 and ADAM17. Molecular Neurodegeneration. 4: 17. PMID 19371428 DOI: 10.1186/1750-1326-4-17  0.313
2008 Zou F, Gopalraj RK, Lok J, Zhu H, Ling IF, Simpson JF, Tucker HM, Kelly JF, Younkin SG, Dickson DW, Petersen RC, Graff-Radford NR, Bennett DA, Crook JE, Younkin SG, ... Estus S, et al. Sex-dependent association of a common low-density lipoprotein receptor polymorphism with RNA splicing efficiency in the brain and Alzheimer's disease. Human Molecular Genetics. 17: 929-35. PMID 18065781 DOI: 10.1093/Hmg/Ddm365  0.772
2008 Zhu H, Taylor JW, Bennett DA, Younkin SG, Estus S. Lack of association of hepatic lipase polymorphisms with late-onset Alzheimer's disease. Neurobiology of Aging. 29: 793-4. PMID 17175070 DOI: 10.1016/J.Neurobiolaging.2006.11.015  0.366
2008 Ling I-, Estus S. P4-229: SNP regulation of LDLR splicing efficiency Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.2297  0.307
2008 Estus S. S1-04-01: Functional polymorphisms in low-density lipoprotein receptor, brain APOE receptor, and Alzheimer's disease risk Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.204  0.362
2007 Zhu H, Tucker HM, Grear KE, Simpson JF, Manning AK, Cupples LA, Estus S. A common polymorphism decreases low-density lipoprotein receptor exon 12 splicing efficiency and associates with increased cholesterol. Human Molecular Genetics. 16: 1765-72. PMID 17517690 DOI: 10.1093/Hmg/Ddm124  0.384
2006 Rebeck GW, LaDu MJ, Estus S, Bu G, Weeber EJ. The generation and function of soluble apoE receptors in the CNS. Molecular Neurodegeneration. 1: 15. PMID 17062143 DOI: 10.1186/1750-1326-1-15  0.385
2005 Zhu H, Gopalraj RK, Kelly JF, Bennett DA, Estus S. Lack of genetic association of cholesteryl ester transfer protein polymorphisms with late onset Alzheimers disease. Neuroscience Letters. 381: 36-41. PMID 15882786 DOI: 10.1016/J.Neulet.2005.01.078  0.769
2005 Gopalraj RK, Zhu H, Kelly JF, Mendiondo M, Pulliam JF, Bennett DA, Estus S. Genetic association of low density lipoprotein receptor and Alzheimer's disease. Neurobiology of Aging. 26: 1-7. PMID 15585340 DOI: 10.1016/J.Neurobiolaging.2004.09.001  0.771
2004 McCollum AT, Estus S. NGF acts via p75 low-affinity neurotrophin receptor and calpain inhibition to reduce UV neurotoxicity. Journal of Neuroscience Research. 77: 552-64. PMID 15264225 DOI: 10.1002/Jnr.20184  0.755
2004 Estus S, Goplaraj RK, Zhu H, Tucker M, Simpson J, Bennett DA. P4-098 Evaluation of polymorphisms in LDLR for altering risk of late onset Alzheimers disease Neurobiology of Aging. 25: S502. DOI: 10.1016/S0197-4580(04)81656-7  0.355
2004 Schmitt FA, Estus S. Alzheimer's disease genetic susceptibility and causality: What is ApoE's impact? Neurobiology of Aging. 25: 661-662. DOI: 10.1016/J.Neurobiolaging.2004.02.008  0.314
2003 Bruckner SR, Perry G, Estus S. 4-hydroxynonenal contributes to NGF withdrawal-induced neuronal apoptosis. Journal of Neurochemistry. 85: 999-1005. PMID 12716431 DOI: 10.1046/J.1471-4159.2003.01749.X  0.761
2003 Bu J, Bruckner SR, Sengoku T, Geddes JW, Estus S. Glutamate regulates caveolin expression in rat hippocampal neurons. Journal of Neuroscience Research. 72: 185-90. PMID 12671992 DOI: 10.1002/Jnr.10556  0.749
2002 Tucker HM, Estus S. Evolution and the scientific method. Neurobiology of Aging. 23: 1093-5. PMID 12470808 DOI: 10.1016/S0197-4580(02)00039-8  0.397
2002 Bruckner SR, Estus S. JNK3 contributes to c-jun induction and apoptosis in 4-hydroxynonenal-treated sympathetic neurons. Journal of Neuroscience Research. 70: 665-70. PMID 12424734 DOI: 10.1002/Jnr.10437  0.76
2002 Bruce-Keller AJ, Estus S. Concern over the amyloid vaccine: amyloid heterogeneity and Fc receptor signaling. Neurobiology of Aging. 23: 667-70; discussion 6. PMID 12392768 DOI: 10.1016/S0197-4580(02)00032-5  0.394
2002 McCollum AT, Nasr P, Estus S. Calpain activates caspase-3 during UV-induced neuronal death but only calpain is necessary for death. Journal of Neurochemistry. 82: 1208-20. PMID 12358768 DOI: 10.1046/J.1471-4159.2002.01057.X  0.752
2002 Tucker HM, Kihiko-Ehmann M, Estus S. Urokinase-type plasminogen activator inhibits amyloid-beta neurotoxicity and fibrillogenesis via plasminogen. Journal of Neuroscience Research. 70: 249-55. PMID 12271474 DOI: 10.1002/Jnr.10417  0.356
2002 Okazawa H, Estus S. The JNK/c-Jun cascade and Alzheimer's disease. American Journal of Alzheimer's Disease and Other Dementias. 17: 79-88. PMID 11954673 DOI: 10.1177/153331750201700209  0.426
2001 Bruckner SR, Tammariello SP, Kuan CY, Flavell RA, Rakic P, Estus S. JNK3 contributes to c-Jun activation and apoptosis but not oxidative stress in nerve growth factor-deprived sympathetic neurons. Journal of Neurochemistry. 78: 298-303. PMID 11461965 DOI: 10.1046/J.1471-4159.2001.00400.X  0.757
2001 Dhillon HS, Dong GX, Yurek DM, Estus S, Rangnekar VM, Dendle P, Prasad RM. Regional expression of Par-4 mRNA and protein after fluid percussion brain injury in the rat. Experimental Neurology. 170: 140-8. PMID 11421591 DOI: 10.1006/Exnr.2001.7685  0.351
2001 Tammariello SP, Landreth GE, Estus S. The role of Jun kinases in apoptosis Advances in Cell Aging and Gerontology. 5: 197-214. DOI: 10.1016/S1566-3124(01)05007-6  0.318
2000 Tucker HM, Kihiko-Ehmann M, Wright S, Rydel RE, Estus S. Tissue plasminogen activator requires plasminogen to modulate amyloid-β neurotoxicity and deposition Journal of Neurochemistry. 75: 2172-2177. PMID 11032907 DOI: 10.1046/J.1471-4159.2000.0752172.X  0.399
2000 Nair P, Tammariello SP, Estus S. Ceramide selectively inhibits apoptosis-associated events in NGF-deprived sympathetic neurons Cell Death and Differentiation. 7: 207-214. PMID 10713735 DOI: 10.1038/Sj.Cdd.4400628  0.448
2000 Tammariello SP, Quinn MT, Estus S. NADPH oxidase contributes directly to oxidative stress and apoptosis in nerve growth factor-deprived sympathetic neurons The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20. PMID 10627630 DOI: 10.1523/Jneurosci.20-01-J0006.2000  0.409
2000 Tucker HM, Kihiko M, Caldwell JN, Wright S, Kawarabayashi T, Price D, Walker D, Scheff S, McGillis JP, Rydel RE, Estus S. The Plasmin System Is Induced by and Degrades Amyloid-β Aggregates The Journal of Neuroscience. 20: 3937-3946. DOI: 10.1523/Jneurosci.20-11-03937.2000  0.383
1999 Kihiko ME, Tucker HM, Rydel RE, Estus S. c-Jun contributes to amyloid β-induced neuronal apoptosis but is not necessary for amyloid β-induced c-jun induction Journal of Neurochemistry. 73: 2609-2612. PMID 10582624 DOI: 10.1046/J.1471-4159.1999.0732609.X  0.419
1999 Aksenov MY, Tucker HM, Nair P, Aksenova MV, Butterfield DA, Estus S, Markesbery WR. The expression of several mitochondrial and nuclear genes encoding the subunits of electron transport chain enzyme complexes, cytochrome c oxidase, and NADH dehydrogenase, in different brain regions in Alzheimer's disease. Neurochemical Research. 24: 767-74. PMID 10447460 DOI: 10.1023/A:1020783614031  0.369
1998 Aksenov MY, Tucker HM, Nair P, Aksenova MV, Butterfield DA, Estus S, Markesbery WR. The expression of key oxidative stress-handling genes in different brain regions in Alzheimer's disease. Journal of Molecular Neuroscience : Mn. 11: 151-64. PMID 10096042 DOI: 10.1385/Jmn:11:2:151  0.363
1998 Tucker HM, Rydel RE, Wright S, Estus S. Human amylin induces 'apoptotic' pattern of gene expression concomitant with cortical neuronal apoptosis Journal of Neurochemistry. 71: 506-516. PMID 9681440 DOI: 10.1046/J.1471-4159.1998.71020506.X  0.415
1997 Estus S, Tucker HM, Van Rooyen C, Wright S, Brigham EF, Wogulis M, Rydel RE. Aggregated amyloid-β protein induces cortical neuronal apoptosis and concomitant 'apoptotic' pattern of gene induction Journal of Neuroscience. 17: 7736-7745. PMID 9315895  0.334
1997 Furukawa K, Estus S, Fu W, Mark RJ, Mattson MP. Neuroprotective action of cycloheximide involves induction of bcl-2 and antioxidant pathways. The Journal of Cell Biology. 136: 1137-49. PMID 9060477 DOI: 10.1083/Jcb.136.5.1137  0.424
1997 Estus S, Tucker HM, Rooyen Cv, Wright S, Brigham EF, Wogulis M, Rydel RE. Aggregated Amyloid-Beta Protein Induces Cortical Neuronal Apoptosis and Concomitant "Apoptotic" Pattern of Gene Induction The Journal of Neuroscience. 17: 7736-7745. DOI: 10.1523/Jneurosci.17-20-07736.1997  0.445
1996 Rydel RE, Bard F, Brigham EF, Wogulis M, Wright S, vanRooyen C, Estus S. 410 Molecular characterization of cellular responses to amyloid-β peptide: Studies utilizing human cortical neurons and microglial cells Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80412-X  0.313
1994 Kotzbauer PT, Lampe PA, Estus S, Milbrandt J, Johnson EM. Postnatal development of survival responsiveness in rat sympathetic neurons to leukemia inhibitory factor and ciliary neurotrophic factor Neuron. 12: 763-773. PMID 8161448 DOI: 10.1016/0896-6273(94)90329-8  0.379
1994 Freeman RS, Estus S, Johnson EM. Analysis of cell cycle-related gene expression in postmitotic neurons: selective induction of Cyclin D1 during programmed cell death. Neuron. 12: 343-55. PMID 8110463 DOI: 10.1016/0896-6273(94)90276-3  0.386
1994 Estus S, Zaks WJ, Freeman RS, Gruda M, Bravo R, Johnson EM. Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis. The Journal of Cell Biology. 127: 1717-27. PMID 7798322 DOI: 10.1083/Jcb.127.6.1717  0.412
1992 Estus S, Golde TE, Younkin SG. Normal processing of the Alzheimer's disease amyloid beta protein precursor generates potentially amyloidogenic carboxyl-terminal derivatives. Annals of the New York Academy of Sciences. 674: 138-48. PMID 1288359 DOI: 10.1111/J.1749-6632.1992.Tb27483.X  0.312
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