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Deborah A. O'Brien - Publications

Affiliations: 
Cell & Developmental Biology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Cell Biology, Evolution and Development Biology, Genetics
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52 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Goodson SG, White S, Stevans AM, Bhat S, Kao CY, Jaworski S, Marlowe TR, Kohlmeier M, McMillan L, Zeisel SH, O'Brien DA. CASAnova: a multiclass support vector machine model for the classification of human sperm motility patterns. Biology of Reproduction. PMID 29036474 DOI: 10.1093/Biolre/Iox120  0.758
2017 Huang Z, Danshina PV, Mohr K, Qu W, Goodson SG, O'Connell TM, O'Brien DA. Sperm function, protein phosphorylation and metabolism differ in mice lacking successive sperm-specific glycolytic enzymes. Biology of Reproduction. PMID 29025010 DOI: 10.1093/Biolre/Iox103  0.778
2016 Danshina PV, Qu W, Temple BR, Rojas RJ, Miley MJ, Machius M, Betts L, O'Brien DA. Structural analyses to identify selective inhibitors of glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme. Molecular Human Reproduction. PMID 26921398 DOI: 10.1093/Molehr/Gaw016  0.349
2015 Odet F, Pan W, Bell TA, Goodson SG, Stevans AM, Yun Z, Aylor DL, Kao CY, McMillan L, Pardo-Manuel de Villena F, O'Brien DA. The Founder Strains of the Collaborative Cross Express a Complex Combination of Advantageous and Deleterious Traits for Male Reproduction. G3 (Bethesda, Md.). PMID 26483008 DOI: 10.1534/G3.115.020172  0.751
2015 Didion JP, Morgan AP, Clayshulte AM, Mcmullan RC, Yadgary L, Petkov PM, Bell TA, Gatti DM, Crowley JJ, Hua K, Aylor DL, Bai L, Calaway M, Chesler EJ, French JE, et al. A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2. Plos Genetics. 11: e1004850. PMID 25679959 DOI: 10.1371/Journal.Pgen.1004850  0.352
2012 Goodson SG, Qiu Y, Sutton KA, Xie G, Jia W, O'Brien DA. Metabolic substrates exhibit differential effects on functional parameters of mouse sperm capacitation. Biology of Reproduction. 87: 75. PMID 22837480 DOI: 10.1095/Biolreprod.112.102673  0.758
2012 Iraqi FA, Mahajne M, Salaymah Y, Sandovski H, Tayem H, Vered K, Balmer L, Hall M, Manship G, Morahan G, Pettit K, Scholten J, Tweedie K, Wallace A, Weerasekera L, et al. The genome architecture of the collaborative cross mouse genetic reference population Genetics. 190: 389-401. PMID 22345608 DOI: 10.1534/Genetics.111.132639  0.726
2011 Sexton JZ, Danshina PV, Lamson DR, Hughes M, House AJ, Yeh LA, O'Brien DA, Williams KP. Development and Implementation of a High Throughput Screen for the Human Sperm-Specific Isoform of Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDHS). Current Chemical Genomics. 5: 30-41. PMID 21760877 DOI: 10.2174/1875397301105010030  0.333
2011 Goodson SG, Zhang Z, Tsuruta JK, Wang W, O'Brien DA. Classification of mouse sperm motility patterns using an automated multiclass support vector machines model. Biology of Reproduction. 84: 1207-15. PMID 21349820 DOI: 10.1095/Biolreprod.110.088989  0.759
2011 Lamson DR, House AJ, Danshina PV, Sexton JZ, Sanyang K, O'Brien DA, Yeh LA, Williams KP. Recombinant human sperm-specific glyceraldehyde-3-phosphate dehydrogenase (GAPDHS) is expressed at high yield as an active homotetramer in baculovirus-infected insect cells. Protein Expression and Purification. 75: 104-13. PMID 20828617 DOI: 10.1016/J.Pep.2010.09.003  0.378
2011 Goodson SG, Qiu Y, Xie G, Jia W, O'Brien DA. Glycolytic Substrates Have Differential Effects on Mouse Sperm Capacitation and Hyperactivation. Biology of Reproduction. 85: 187-187. DOI: 10.1093/Biolreprod/85.S1.187  0.753
2010 Goto M, O'Brien DA, Eddy EM. Speriolin is a novel human and mouse sperm centrosome protein. Human Reproduction (Oxford, England). 25: 1884-94. PMID 20542897 DOI: 10.1093/humrep/deq138  0.303
2010 Vemuganti SA, de Villena FP, O'Brien DA. Frequent and recent retrotransposition of orthologous genes plays a role in the evolution of sperm glycolytic enzymes. Bmc Genomics. 11: 285. PMID 20459611 DOI: 10.1186/1471-2164-11-285  0.764
2010 Danshina PV, Geyer CB, Dai Q, Goulding EH, Willis WD, Kitto GB, McCarrey JR, Eddy EM, O'Brien DA. Phosphoglycerate kinase 2 (PGK2) is essential for sperm function and male fertility in mice. Biology of Reproduction. 82: 136-45. PMID 19759366 DOI: 10.1095/Biolreprod.109.079699  0.493
2010 Goodson SG, Zhang Z, Tsuruta JK, Wang W, O'Brien DA. A Multiclass Support Vector Machine Model for the Identification of Sperm Motility Patterns in Heterogeneous Populations. Biology of Reproduction. 83: 140-140. DOI: 10.1093/Biolreprod/83.S1.140  0.73
2009 Hu Y, Yu H, Pask AJ, O'Brien DA, Shaw G, Renfree MB. A-kinase anchoring protein 4 has a conserved role in mammalian spermatogenesis. Reproduction (Cambridge, England). 137: 645-53. PMID 19139142 DOI: 10.1530/Rep-08-0337  0.354
2008 Kaneto M, Krisfalusi M, Eddy EM, O'Brien DA, Miki K. Bicarbonate-induced phosphorylation of p270 protein in mouse sperm by cAMP-dependent protein kinase. Molecular Reproduction and Development. 75: 1045-53. PMID 18357561 DOI: 10.1002/Mrd.20839  0.367
2008 Sawyer GM, Monzingo AF, Poteet EC, O'Brien DA, Robertus JD. X-ray analysis of phosphoglycerate kinase 2, a sperm-specific isoform from Mus musculus. Proteins. 71: 1134-44. PMID 18004764 DOI: 10.1002/Prot.21801  0.323
2008 Nakamura N, Shibata H, O'Brien DA, Mori C, Eddy EM. Spermatogenic cell-specific type 1 hexokinase is the predominant hexokinase in sperm. Molecular Reproduction and Development. 75: 632-40. PMID 17924400 DOI: 10.1002/Mrd.20791  0.418
2008 O'Brien DA. Novel Sperm Glycolytic Enzymes as Contraceptive Targets. Biology of Reproduction. 78: 273-274. DOI: 10.1093/Biolreprod/78.S1.273C  0.319
2007 Vemuganti SA, Bell TA, Scarlett CO, Parker CE, de Villena FP, O'Brien DA. Three male germline-specific aldolase A isozymes are generated by alternative splicing and retrotransposition. Developmental Biology. 309: 18-31. PMID 17659271 DOI: 10.1016/J.Ydbio.2007.06.010  0.77
2007 Buchold GM, Magyar PL, O'Brien DA. Mice lacking cyclin-dependent kinase inhibitor p19Ink4d show strain-specific effects on male reproduction. Molecular Reproduction and Development. 74: 1008-20. PMID 17393423 DOI: 10.1002/Mrd.20715  0.766
2007 Buchold GM, Magyar PL, Arumugam R, Lee MM, O'Brien DA. p19Ink4d and p18Ink4c cyclin-dependent kinase inhibitors in the male reproductive axis. Molecular Reproduction and Development. 74: 997-1007. PMID 17342741 DOI: 10.1002/Mrd.20716  0.755
2007 O'Brien D. NOVEL GLYCOLYTIC ENZYMES ARE ESSENTIAL FOR SPERM FUNCTION AND MALE FERTILITY Biology of Reproduction. 77: 64-65. DOI: 10.1093/Biolreprod/77.S1.64D  0.4
2006 Yuan W, Leisner TM, McFadden AW, Clark S, Hiller S, Maeda N, O'Brien DA, Parise LV. CIB1 is essential for mouse spermatogenesis. Molecular and Cellular Biology. 26: 8507-14. PMID 16982698 DOI: 10.1128/Mcb.01488-06  0.419
2006 Welch JE, Barbee RR, Magyar PL, Bunch DO, O'Brien DA. Expression of the spermatogenic cell-specific glyceraldehyde 3-phosphate dehydrogenase (GAPDS) in rat testis. Molecular Reproduction and Development. 73: 1052-60. PMID 16700075 DOI: 10.1002/Mrd.20235  0.331
2006 Krisfalusi M, Miki K, Magyar PL, O'Brien DA. Multiple glycolytic enzymes are tightly bound to the fibrous sheath of mouse spermatozoa. Biology of Reproduction. 75: 270-8. PMID 16687649 DOI: 10.1095/Biolreprod.105.049684  0.374
2005 Holsberger DR, Buchold GM, Leal MC, Kiesewetter SE, O'Brien DA, Hess RA, França LR, Kiyokawa H, Cooke PS. Cell-cycle inhibitors p27Kip1 and p21Cip1 regulate murine Sertoli cell proliferation. Biology of Reproduction. 72: 1429-36. PMID 15728790 DOI: 10.1095/Biolreprod.105.040386  0.745
2004 Miki K, Qu W, Goulding EH, Willis WD, Bunch DO, Strader LF, Perreault SD, Eddy EM, O'Brien DA. Glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme, is required for sperm motility and male fertility. Proceedings of the National Academy of Sciences of the United States of America. 101: 16501-6. PMID 15546993 DOI: 10.1073/Pnas.0407708101  0.49
2003 Eddy EM, Toshimori K, O'Brien DA. Fibrous sheath of mammalian spermatozoa. Microscopy Research and Technique. 61: 103-15. PMID 12672126 DOI: 10.1002/Jemt.10320  0.411
2003 Yang G, Zhang YL, Buchold GM, Jetten AM, O'Brien DA. Analysis of germ cell nuclear factor transcripts and protein expression during spermatogenesis. Biology of Reproduction. 68: 1620-30. PMID 12606326 DOI: 10.1095/Biolreprod.102.012013  0.742
2000 Franklin DS, Godfrey VL, O'Brien DA, Deng C, Xiong Y. Functional collaboration between different cyclin-dependent kinase inhibitors suppresses tumor growth with distinct tissue specificity Molecular and Cellular Biology. 20: 6147-6158. PMID 10913196 DOI: 10.1128/Mcb.20.16.6147-6158.2000  0.331
2000 Welch JE, Brown PL, O'Brien DA, Magyar PL, Bunch DO, Mori C, Eddy EM. Human glyceraldehyde 3-phosphate dehydrogenase-2 gene is expressed specifically in spermatogenic cells Journal of Andrology. 21: 328-338. PMID 10714828 DOI: 10.1002/J.1939-4640.2000.Tb02111.X  0.367
1999 McCarrey JR, O'Brien DA, Skinner MK. Construction and preliminary characterization of a series of mouse and rat testis cDNA libraries Journal of Andrology. 20: 635-639. PMID 10520576 DOI: 10.1002/J.1939-4640.1999.Tb02565.X  0.313
1998 Zhang YL, Akmal KM, Tsuruta JK, Shang Q, Hirose T, Jetten AM, Kim KH, O'Brien DA. Expression of germ cell nuclear factor (GCNF/RTR) during spermatogenesis Molecular Reproduction and Development. 50: 93-102. PMID 9547515 DOI: 10.1002/(Sici)1098-2795(199805)50:1<93::Aid-Mrd12>3.0.Co;2-Z  0.337
1998 Bunch DO, Welch JE, Magyar PL, Eddy EM, O'Brien DA. Glyceraldehyde 3-phosphate dehydrogenase-S protein distribution during mouse spermatogenesis Biology of Reproduction. 58: 834-841. PMID 9510974 DOI: 10.1095/Biolreprod58.3.834  0.336
1998 Eddy EM, O'Brien DA. Gene expression during mammalian meiosis Current Topics in Developmental Biology. 37: 141-200. PMID 9352186 DOI: 10.1016/S0070-2153(08)60174-X  0.348
1997 Joseph DR, O'Brien DA, Sullivan PM, Becchis M, Tsuruta JK, Petrusz P. Overexpression of androgen-binding protein/sex hormone-binding globulin in male transgenic mice: Tissue distribution and phenotypic disorders Biology of Reproduction. 56: 21-32. PMID 9002629 DOI: 10.1095/Biolreprod56.1.21  0.379
1996 O'Brien DA, Welch JE, Goulding EH, Taylor AA, Baba T, Hecht NB, Eddy EM. Boar proacrosin expressed in spermatids of transgenic mice does not reach the acrosome and disrupts spermatogenesis. Molecular Reproduction and Development. 43: 236-47. PMID 8824922 DOI: 10.1002/(Sici)1098-2795(199602)43:2<236::Aid-Mrd13>3.0.Co;2-1  0.419
1995 Fulcher KD, Welch JE, Klapper DG, O'Brien DA, Eddy EM. Identification of a unique μ-class glutathione S-transferase in mouse spermatogenic cells Molecular Reproduction and Development. 42: 415-424. PMID 8607970 DOI: 10.1002/Mrd.1080420407  0.358
1995 Hirose T, O'Brien DA, Jetten AM. RTR: a new member of the nuclear receptor superfamily that is highly expressed in murine testis Gene. 152: 247-251. PMID 7835709 DOI: 10.1016/0378-1119(94)00656-D  0.335
1995 Krege JH, John SW, Langenbach LL, Hodgin JB, Hagaman JR, Bachman ES, Jennette JC, O'Brien DA, Smithies O. Male-female differences in fertility and blood pressure in ACE-deficient mice. Nature. 375: 146-8. PMID 7753170 DOI: 10.1038/375146A0  0.355
1995 Welch JE, Brown PR, O'Brien DA, Eddy EM. Genomic organization of a mouse glyceraldehyde 3-phosphate dehydrogenase gene (Gapd-s) expressed in post-meiotic spermatogenic cells Developmental Genetics. 16: 179-189. PMID 7736666 DOI: 10.1002/Dvg.1020160210  0.358
1995 Hirose T, O'Brien DA, Jetten AM. Cloning of the gene encoding the murine orphan receptor TAK1 and cell-type-specific expression in testis Gene. 163: 239-242. PMID 7590273 DOI: 10.1016/0378-1119(95)00414-2  0.355
1995 Raburn DJ, Hamil KG, Tsuruta JK, O'Brien DA, Hall SH. Stage-specific expression of B cell translocation gene 1 in rat testis Endocrinology. 136: 5769-5777. PMID 7588335 DOI: 10.1210/Endo.136.12.7588335  0.334
1992 Rosario MO, Perkins SL, O'Brien DA, Allen RL, Eddy EM. Identification of the gene for the developmentally expressed 70 kDa heat-shock protein (P70) of mouse spermatogenic cells. Developmental Biology. 150: 1-11. PMID 1537426 DOI: 10.1016/0012-1606(92)90002-X  0.347
1992 Welch JE, Schatte EC, O'Brien DA, Eddy EM. Expression of a glyceraldehyde 3-phosphate dehydrogenase gene specific to mouse spermatogenic cells Biology of Reproduction. 46: 869-878. PMID 1375514 DOI: 10.1095/Biolreprod46.5.869  0.38
1992 Welch JE, Swinnen JV, O'Brien DA, Eddy EM, Conti M. Unique adenosine 3',5' cyclic monophosphate phosphodiesterase messenger ribonucleic acids in rat spermatogenic cells: Evidence for differential gene expression during spermatogenesis Biology of Reproduction. 46: 1027-1033. PMID 1327199 DOI: 10.1095/Biolreprod46.6.1027  0.366
1991 Eddy EM, O'Brien DA, Fenderson BA, Welch JE. Intermediate filament-like proteins in the fibrous sheath of the mouse sperm flagellum Annals of the New York Academy of Sciences. 637: 224-239. PMID 1723852 DOI: 10.1111/J.1749-6632.1991.Tb27312.X  0.351
1991 O'Brien DA, Gabel CA, Welch JE, Eddy EM. Mannose 6-phosphate receptors: Potential mediators of germ cell-Sertoli cell interactions Annals of the New York Academy of Sciences. 637: 327-339. PMID 1664679 DOI: 10.1111/J.1749-6632.1991.Tb27320.X  0.327
1988 Allen RL, O'Brien DA, Eddy EM. A novel hsp70-like protein (P70) is present in mouse spermatogenic cells. Molecular and Cellular Biology. 8: 828-32. PMID 3352605 DOI: 10.1128/Mcb.8.2.828  0.312
1988 Allen RL, O'Brien DA, Jones CC, Rockett DL, Eddy EM. Expression of heat shock proteins by isolated mouse spermatogenic cells. Molecular and Cellular Biology. 8: 3260-6. PMID 3211143 DOI: 10.1128/Mcb.8.8.3260  0.317
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