Gerrit L. Scherphof, Ph.D. - Publications

Affiliations: 
University of Groningen, Groningen, Netherlands 
Area:
Physiological chemistry
Website:
http://hoogleraren.ub.rug.nl/index.php?page=showPerson&type=hoogleraar&hoogleraar_id=2088

129 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Kowalski PS, Leus NG, Scherphof GL, Ruiters MH, Kamps JA, Molema G. Targeted siRNA delivery to diseased microvascular endothelial cells: cellular and molecular concepts. Iubmb Life. 63: 648-58. PMID 21766413 DOI: 10.1002/Iub.487  0.312
2007 Weeke-Klimp AH, Bartsch M, Morselt HW, Van Veen-Hof I, Meijer DK, Scherphof GL, Kamps JA. Targeting of stabilized plasmid lipid particles to hepatocytes in vivo by means of coupled lactoferrin. Journal of Drug Targeting. 15: 585-94. PMID 17968712 DOI: 10.1080/10611860701502889  0.444
2007 Adrian JE, Kamps JA, Scherphof GL, Meijer DK, van Loenen-Weemaes AM, Reker-Smit C, Terpstra P, Poelstra K. A novel lipid-based drug carrier targeted to the non-parenchymal cells, including hepatic stellate cells, in the fibrotic livers of bile duct ligated rats. Biochimica Et Biophysica Acta. 1768: 1430-9. PMID 17493581 DOI: 10.1016/J.Bbamem.2007.03.027  0.489
2007 Adrian JE, Kamps JA, Poelstra K, Scherphof GL, Meijer DK, Kaneda Y. Delivery of viral vectors to hepatic stellate cells in fibrotic livers using HVJ envelopes fused with targeted liposomes. Journal of Drug Targeting. 15: 75-82. PMID 17365276 DOI: 10.1080/10611860601141481  0.436
2007 Adrian JE, Poelstra K, Scherphof GL, Meijer DK, van Loenen-Weemaes AM, Reker-Smit C, Morselt HW, Zwiers P, Kamps JA. Effects of a new bioactive lipid-based drug carrier on cultured hepatic stellate cells and liver fibrosis in bile duct-ligated rats. The Journal of Pharmacology and Experimental Therapeutics. 321: 536-43. PMID 17314198 DOI: 10.1124/Jpet.106.117945  0.462
2006 Adrian JE, Poelstra K, Scherphof GL, Molema G, Meijer DK, Reker-Smit C, Morselt HW, Kamps JA. Interaction of targeted liposomes with primary cultured hepatic stellate cells: Involvement of multiple receptor systems. Journal of Hepatology. 44: 560-7. PMID 16368158 DOI: 10.1016/J.Jhep.2005.08.027  0.474
2005 Bartsch M, Weeke-Klimp AH, Meijer DK, Scherphof GL, Kamps JA. Cell-specific targeting of lipid-based carriers for ODN and DNA. Journal of Liposome Research. 15: 59-92. PMID 16194928 DOI: 10.1081/Lpr-64961  0.351
2005 Yan X, Kuipers F, Havekes LM, Havinga R, Dontje B, Poelstra K, Scherphof GL, Kamps JA. The role of apolipoprotein E in the elimination of liposomes from blood by hepatocytes in the mouse. Biochemical and Biophysical Research Communications. 328: 57-62. PMID 15670750 DOI: 10.1016/J.Bbrc.2004.12.137  0.317
2005 Rothkopf C, Fahr A, Fricker G, Scherphof GL, Kamps JA. Uptake of phosphatidylserine-containing liposomes by liver sinusoidal endothelial cells in the serum-free perfused rat liver. Biochimica Et Biophysica Acta. 1668: 10-6. PMID 15670726 DOI: 10.1016/J.Bbamem.2004.10.013  0.473
2005 Bartsch M, Weeke-Klimp AH, Morselt HW, Kimpfler A, Asgeirsdóttir SA, Schubert R, Meijer DK, Scherphof GL, Kamps JA. Optimized targeting of polyethylene glycol-stabilized anti-intercellular adhesion molecule 1 oligonucleotide/lipid particles to liver sinusoidal endothelial cells. Molecular Pharmacology. 67: 883-90. PMID 15598973 DOI: 10.1124/Mol.104.004523  0.387
2004 Bartsch M, Weeke-Klimp AH, Hoenselaar EP, Stuart MC, Meijer DK, Scherphof GL, Kamps JA. Stabilized lipid coated lipoplexes for the delivery of antisense oligonucleotides to liver endothelial cells in vitro and in vivo. Journal of Drug Targeting. 12: 613-21. PMID 15621687 DOI: 10.1080/10611860400013519  0.437
2004 Yan X, Morselt HW, Scherphof GL, Poelstra K, Kamps JA. The role of beta2-glycoprotein I in liposome-hepatocyte interaction. Biochimica Et Biophysica Acta. 1667: 208-14. PMID 15581857 DOI: 10.1016/J.Bbamem.2004.10.008  0.41
2004 Yan X, Poelstra K, Scherphof GL, Kamps JA. A role for scavenger receptor B-I in selective transfer of rhodamine-PE from liposomes to cells. Biochemical and Biophysical Research Communications. 325: 908-14. PMID 15541376 DOI: 10.1016/J.Bbrc.2004.10.104  0.323
2004 Kamps JA, Scherphof GL. Biodistribution and uptake of liposomes in vivo. Methods in Enzymology. 387: 257-66. PMID 15172169 DOI: 10.1016/S0076-6879(04)87016-2  0.347
2004 Braet F, Vekemans K, Morselt H, De Zanger R, Wisse E, Scherphof G, Kamps J. The effect of cytochalasin B - Loaded liposomes on the ultrastructure of the liver sieve. Comparative Hepatology. S27. PMID 14960179 DOI: 10.1186/1476-5926-2-S1-S27  0.424
2003 Koning GA, Morselt HW, Gorter A, Allen TM, Zalipsky S, Scherphof GL, Kamps JA. Interaction of differently designed immunoliposomes with colon cancer cells and Kupffer cells. An in vitro comparison. Pharmaceutical Research. 20: 1249-57. PMID 12948023 DOI: 10.1023/A:1025009300562  0.375
2003 Bartsch M, Meijer DKF, Scherphof GL, Kamps JAAM. Targeted Delivery of Antisense Oligodeoxynucleotides In Vivo by Means of Coated Cationic Lipoplexes Journal of Liposome Research. 13: 37-38. PMID 12784824 DOI: 10.1081/Lpr-120017489  0.451
2003 Bendas G, Rothe U, Scherphof GL, Kamps JA. The influence of repeated injections on pharmacokinetics and biodistribution of different types of sterically stabilized immunoliposomes. Biochimica Et Biophysica Acta. 1609: 63-70. PMID 12507759 DOI: 10.1016/S0005-2736(02)00655-7  0.307
2002 Koning GA, Kamps JA, Scherphof GL. Interference of macrophages with immunotargeting of liposomes. Journal of Liposome Research. 12: 107-19. PMID 12604044 DOI: 10.1081/Lpr-120004782  0.423
2002 Koning GA, Kamps JA, Scherphof GL. Efficient intracellular delivery of 5-fluorodeoxyuridine into colon cancer cells by targeted immunoliposomes. Cancer Detection and Prevention. 26: 299-307. PMID 12430634 DOI: 10.1016/S0361-090X(02)00087-9  0.387
2002 Klimp AH, de Vries EG, Scherphof GL, Daemen T. A potential role of macrophage activation in the treatment of cancer. Critical Reviews in Oncology/Hematology. 44: 143-61. PMID 12413632 DOI: 10.1016/S1040-8428(01)00203-7  0.312
2002 Scherphof GL, Koning G, Bartsch M, Yan X, Kamps J. Targeting liposomes and lipoplexes to cells in the liver. Cellular & Molecular Biology Letters. 7: 251-4. PMID 12097938  0.327
2002 Bartsch M, Weeke-Klimp AH, Meijer DK, Scherphof GL, Kamps JA. Massive and selective delivery of lipid-coated cationic lipoplexes of oligonucleotides targeted in vivo to hepatic endothelial cells. Pharmaceutical Research. 19: 676-80. PMID 12069172 DOI: 10.1023/A:1015318415705  0.455
2001 Koning GA, Morselt HW, Kamps JA, Scherphof GL. Uptake and intracellular processing of PEG-liposomes and PEG-immunoliposomes by kupffer cells in vitro 1 *. Journal of Liposome Research. 11: 195-209. PMID 19530933 DOI: 10.1081/Lpr-100108462  0.451
2001 Koning GA, Morselt HW, Gorter A, Allen TM, Zalipsky S, Kamps JA, Scherphof GL. Pharmacokinetics of differently designed immunoliposome formulations in rats with or without hepatic colon cancer metastases. Pharmaceutical Research. 18: 1291-8. PMID 11683242 DOI: 10.1023/A:1013085811044  0.378
2001 Klimp AH, van der Vaart E, Lansink PO, Withoff S, de Vries EG, Scherphof GL, Wilschut J, Daemen T. Activation of peritoneal cells upon in vivo transfection with a recombinant alphavirus expressing GM-CSF. Gene Therapy. 8: 300-7. PMID 11313804 DOI: 10.1038/Sj.Gt.3301385  0.33
2001 Scherphof GL, Kamps JA. The role of hepatocytes in the clearance of liposomes from the blood circulation. Progress in Lipid Research. 40: 149-66. PMID 11275265 DOI: 10.1016/S0163-7827(00)00020-5  0.398
2000 Kamps JA, Koning GA, Velinova MJ, Morselt HW, Wilkens M, Gorter A, Donga J, Scherphof GL. Uptake of long-circulating immunoliposomes, directed against colon adenocarcinoma cells, by liver metastases of colon cancer. Journal of Drug Targeting. 8: 235-45. PMID 11144234 DOI: 10.3109/10611860008997902  0.456
2000 Scherphof GL, Daemen T, Romero EL, Kamps JAAM. Liposome elimination by non-phagocytic cells of the liver Journal of Liposome Research. 10: 431-442. DOI: 10.3109/08982100009031109  0.435
1999 Koning GA, Gorter A, Scherphof GL, Kamps JA. Antiproliferative effect of immunoliposomes containing 5-fluorodeoxyuridine-dipalmitate on colon cancer cells. British Journal of Cancer. 80: 1718-25. PMID 10468287 DOI: 10.1038/Sj.Bjc.6690588  0.416
1999 Koning GA, Morselt HW, Velinova MJ, Donga J, Gorter A, Allen TM, Zalipsky S, Kamps JA, Scherphof GL. Selective transfer of a lipophilic prodrug of 5-fluorodeoxyuridine from immunoliposomes to colon cancer cells. Biochimica Et Biophysica Acta. 1420: 153-67. PMID 10446299 DOI: 10.1016/S0005-2736(99)00091-7  0.446
1999 Klimp AH, Regts J, Scherphof GL, de Vries EG, Daemen T. Effect of intraperitoneally administered recombinant murine granulocyte-macrophage colony-stimulating factor (rmGM-CSF) on the cytotoxic potential of murine peritoneal cells. British Journal of Cancer. 79: 89-94. PMID 10408698 DOI: 10.1038/Sj.Bjc.6690016  0.356
1999 Romero EL, Morilla MJ, Regts J, Koning GA, Scherphof GL. On the mechanism of hepatic transendothelial passage of large liposomes. Febs Letters. 448: 193-6. PMID 10217439 DOI: 10.1016/S0014-5793(99)00364-6  0.381
1999 Kamps JA, Morselt HW, Scherphof GL. Uptake of liposomes containing phosphatidylserine by liver cells in vivo and by sinusoidal liver cells in primary culture: in vivo-in vitro differences. Biochemical and Biophysical Research Communications. 256: 57-62. PMID 10066422 DOI: 10.1006/Bbrc.1999.0290  0.494
1998 Kamps JA, Scherphof GL. Receptor versus non-receptor mediated clearance of liposomes. Advanced Drug Delivery Reviews. 32: 81-97. PMID 10837637 DOI: 10.1016/S0169-409X(97)00133-6  0.387
1998 de Jong KP, Brouwers MA, van Veen ML, Brinker M, de Vries EG, Daemen T, Scherphof GL, Slooff MJ. Serum obtained from rats after partial hepatectomy enhances growth of cultured colon carcinoma cells. Invasion & Metastasis. 18: 155-64. PMID 10474028 DOI: 10.1159/000024508  0.318
1997 Kamps JA, Morselt HW, Swart PJ, Meijer DK, Scherphof GL. Massive targeting of liposomes, surface-modified with anionized albumins, to hepatic endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 94: 11681-5. PMID 9326670 DOI: 10.1073/Pnas.94.21.11681  0.497
1997 Daemen T, Velinova M, Regts J, de Jager M, Kalicharan R, Donga J, van der Want JJ, Scherphof GL. Different intrahepatic distribution of phosphatidylglycerol and phosphatidylserine liposomes in the rat. Hepatology (Baltimore, Md.). 26: 416-23. PMID 9252153 DOI: 10.1002/Hep.510260223  0.469
1997 Shimada K, Kamps JA, Regts J, Ikeda K, Shiozawa T, Hirota S, Scherphof GL. Biodistribution of liposomes containing synthetic galactose-terminated diacylglyceryl-poly(ethyleneglycol)s. Biochimica Et Biophysica Acta. 1326: 329-41. PMID 9218563 DOI: 10.1016/S0005-2736(97)00036-9  0.468
1997 Scherphof GL, Kamps JAAM, Koning Groningen GA. In vivo targeting of surface-modified liposomes to metastatically growing colon carcinoma cells and sinusoidal endothelial cells in the rat liver Journal of Liposome Research. 7: 419-432. DOI: 10.3109/08982109709035510  0.438
1997 Scherphof GL, Velinova M, Kamps J, Donga J, Van der Want H, Kuipers F, Havekes L, Daemen T. Modulation of pharmacokinetic behavior of liposomes Advanced Drug Delivery Reviews. 24: 179-191. DOI: 10.1016/S0169-409X(96)00457-7  0.448
1997 Crommelin DJA, Daemen T, Scherphof GL, Vingerhoeds MH, Heeremans JLM, Kluft C, Storm G. Liposomes: Vehicles for the targeted and controlled delivery of peptides and proteins Journal of Controlled Release. 46: 165-175. DOI: 10.1016/S0168-3659(96)01583-0  0.319
1997 Daemen T, Regts J, Meesters M, Ten Kate MT, Bakker-Woudenberg IAJM, Scherphof GL. Toxicity of doxorubicin entrapped within long-circulating liposomes Journal of Controlled Release. 44: 1-9. DOI: 10.1016/S0168-3659(96)01501-5  0.453
1996 Daemen T, Regts J, Scherphof GL. Liposomal phosphatidylserine inhibits tumor cytotoxicity of liver macrophages induced by muramyl dipeptide and lipopolysaccharide. Biochimica Et Biophysica Acta. 1285: 219-28. PMID 8972706 DOI: 10.1016/S0005-2736(96)00164-2  0.403
1996 Kamps JA, Swart PJ, Morselt HW, Pauwels R, De Béthune MP, De Clercq E, Meijer DK, Scherphof GL. Preparation and characterization of conjugates of (modified) human serum albumin and liposomes: drug carriers with an intrinsic anti-HIV activity. Biochimica Et Biophysica Acta. 1278: 183-90. PMID 8593275 DOI: 10.1016/0005-2736(95)00218-9  0.372
1996 Scherphof GL, Crommelin DJA. Cells involved in removing liposomes from the blood circulation: Why are they so special? Journal of Liposome Research. 6: 19-32. DOI: 10.3109/08982109609037200  0.35
1995 Hoedemakers RM, Morselt HW, Scherphof GL, Daemen T. Heterogeneity in secretory responses of rat liver macrophages of different size. Liver. 15: 313-9. PMID 8609811 DOI: 10.1111/J.1600-0676.1995.Tb00691.X  0.398
1995 Mori A, Kennel SJ, van Borssum Waalkes M, Scherphof GL, Huang L. Characterization of organ-specific immunoliposomes for delivery of 3',5'-O-dipalmitoyl-5-fluoro-2'-deoxyuridine in a mouse lung-metastasis model. Cancer Chemotherapy and Pharmacology. 35: 447-56. PMID 7882453 DOI: 10.1007/Bf00686828  0.323
1995 Daemen T, Hofstede G, Ten Kate MT, Bakker-Woudenberg IA, Scherphof GL. Liposomal doxorubicin-induced toxicity: depletion and impairment of phagocytic activity of liver macrophages. International Journal of Cancer. Journal International Du Cancer. 61: 716-21. PMID 7768646 DOI: 10.1002/Ijc.2910610520  0.457
1995 Hoedemakers RM, Atmosoerodjo-Briggs JE, Morselt HW, Daemen T, Scherphof GL, Hardonk MJ. Histochemical and electron microscopic characterization of hepatic macrophage subfractions isolated from normal and liposomal muramyl dipeptide treated rats. Liver. 15: 113-20. PMID 7674837 DOI: 10.1111/J.1600-0676.1995.Tb00656.X  0.459
1995 Thomas K, Nijenhuis AM, Dontje BH, Daemen T, Scherphof GL. Antitumor reactivity induced by liposomal MTP-PE in a liver metastasis model of colon cancer in the rat. Clinical & Experimental Metastasis. 13: 328-36. PMID 7641418 DOI: 10.1007/BF00121909  0.323
1995 Thomas C, Nijenhuis AM, Dontje B, Daemen T, Scherphof GL. Tumoricidal response of liver macrophages isolated from rats bearing liver metastases of colon adenocarcinoma. Journal of Leukocyte Biology. 57: 617-23. PMID 7536789  0.329
1995 Hoedemakers RMJ, Scherphof GL, Daemen T. Repeated intravenous administration of liposome-encapsulated muramyl tripeptide-phosphatidyl-ethanolamine diminishes cytotoxic potential of subpopulations of rat liver macrophages Journal of Liposome Research. 5: 581-603. DOI: 10.3109/08982109509010243  0.478
1995 Crommelin DJA, Scherphof G, Storm G. Active targeting with particulate carrier systems in the blood compartment Advanced Drug Delivery Reviews. 17: 49-60. DOI: 10.1016/0169-409X(95)00040-E  0.309
1995 Daemen T, Hoedemakers R, Storm G, Scherphof GL. Opportunities in targeted drug delivery to Kupffer cells: delivery of immunomodulators to Kupffer cells-activation of tumoricidal properties Advanced Drug Delivery Reviews. 17: 21-30. DOI: 10.1016/0169-409X(95)00038-9  0.353
1994 Hoedemakers RM, Scherphof GL, Daemen T. Proliferation of rat liver macrophages in vitro: influence of hemopoietic growth factors. Hepatology (Baltimore, Md.). 19: 666-74. PMID 8119691 DOI: 10.1002/Hep.1840190318  0.386
1994 Hoedemakers RM, Morselt HW, Scherphof GL, Daemen T. Secretion pattern of the rat liver macrophage population following activation with liposomal muramyl dipeptide in vivo and in vitro. Journal of Immunotherapy With Emphasis On Tumor Immunology : Official Journal of the Society For Biological Therapy. 15: 265-72. PMID 8061899 DOI: 10.1097/00002371-199405000-00005  0.417
1994 Scherphof GL, Van Borssum Waalkes M. Release of active drug from intracellular liposomal prodrug depots in macrophages controlled by liposome composition Journal of Liposome Research. 4: 427-437. DOI: 10.3109/08982109409037053  0.403
1994 Scherphof GL, Morselt H, Allen TM. Intrahepatic distribution of long-circulating liposomes containing polyethylene glycol) distearoyl phosphatidylethanolamine Journal of Liposome Research. 4: 213-228. DOI: 10.3109/08982109409037038  0.401
1994 Daemen T, Dontje BHJ, Regts J, Morselt H, Scherphof GL. Chemo-emmunotherapy of liver metastases; the in vitro and in vivo effects of 5-fluorouracil combined with liposome-encapsulated muramyl dipeptide Journal of Liposome Research. 4: 27-42. DOI: 10.3109/08982109409037028  0.407
1993 van Borssum Waalkes M, van Galen M, Morselt H, Sternberg B, Scherphof GL. In-vitro stability and cytostatic activity of liposomal formulations of 5-fluoro-2'-deoxyuridine and its diacylated derivatives. Biochimica Et Biophysica Acta. 1148: 161-72. PMID 8499464 DOI: 10.1016/0005-2736(93)90174-X  0.412
1993 van Borssum Waalkes M, Kuipers F, Havinga R, Scherphof GL. Conversion of liposomal 5-fluoro-2'-deoxyuridine and its dipalmitoyl derivative to bile acid conjugates of alpha-fluoro-beta-alanine and their excretion into rat bile. Biochimica Et Biophysica Acta. 1176: 43-50. PMID 8452878 DOI: 10.1016/0167-4889(93)90175-O  0.401
1993 Daemen T, Dontje BH, Regts J, Scherphof GL. Chemoimmunotherapy of murine liver metastases with 5-fluorouracil in combination with liposome-encapsulated muramyl dipeptide. Journal of Immunotherapy With Emphasis On Tumor Immunology : Official Journal of the Society For Biological Therapy. 13: 31-5. PMID 8435429 DOI: 10.1097/00002371-199301000-00004  0.385
1993 Hoedemakers RM, Vossebeld PJ, Daemen T, Scherphof GL. Functional characteristics of the rat liver macrophage population after a single intravenous injection of liposome-encapsulated muramyl peptides. Journal of Immunotherapy With Emphasis On Tumor Immunology : Official Journal of the Society For Biological Therapy. 13: 252-60. PMID 8334109 DOI: 10.1097/00002371-199305000-00004  0.443
1993 Thomas C, Nijenhuis AM, Timens W, Kuppen PJ, Daemen T, Scherphof GL. Liver metastasis model of colon cancer in the rat: immunohistochemical characterization. Invasion & Metastasis. 13: 102-12. PMID 8225852  0.317
1992 Van Borssum Waalkes M, Fichtner I, Dontje B, Lemm M, Becker M, Arndt D, Scherphof GL. In vivo distribution and antitumour activity of liposomal 3',5'-O-dipalmitoyl-5-fluoro-2'-deoxyuridine. Journal of Microencapsulation. 9: 335-46. PMID 1403484 DOI: 10.3109/02652049209021248  0.378
1992 Daemen T, Regts J, Morselt H, Scherphof GL. The effect of liver macrophages on in vitro cytolytic activity of 5FU and FUdR on colon carcinoma cells: evidence of macrophage activation. International Journal of Immunopharmacology. 14: 857-64. PMID 1387390 DOI: 10.1016/0192-0561(92)90084-X  0.382
1991 Daemen T, Veninga A, Regts J, Scherphof GL. Maintenance of tumoricidal activity and susceptibility to reactivation of subpopulations of rat liver macrophages. Journal of Immunotherapy : Official Journal of the Society For Biological Therapy. 10: 200-6. PMID 1868044 DOI: 10.1097/00002371-199106000-00006  0.379
1990 Van Borssum Waalkes M, Scherphof GL. Liposome-incorporated 3',5'-O-dipalmitoyl-5-fluoro-2'-deoxyuridine as a slow-release anti-tumor drug depot in rat liver macrophages. Selective Cancer Therapeutics. 6: 15-22. PMID 2140463  0.379
1989 Roerdink FH, Regts J, Handel T, Sullivan SM, Baldeschwieler JD, Scherphof GL. Effect of cholesterol on the uptake and intracellular degradation of liposomes by liver and spleen; a combined biochemical and gamma-ray perturbed angular correlation study. Biochimica Et Biophysica Acta. 980: 234-40. PMID 2930790 DOI: 10.1016/0005-2736(89)90404-5  0.495
1989 Daemen T, Veninga A, Dijkstra J, Scherphof G. Differential effects of liposome-incorporation on liver macrophage activating potencies of rough lipopolysaccharide, lipid A, and muramyl dipeptide. Differences in susceptibility to lysosomal enzymes Journal of Immunology. 142: 2469-2474. PMID 2926140  0.352
1989 Daemen T, Veninga A, Roerdink FH, Scherphof GL. Conditions controlling tumor cytotoxicity of rat liver macrophages mediated by liposomal muramyl dipeptide. Biochimica Et Biophysica Acta. 991: 145-51. PMID 2713416 DOI: 10.1016/0304-4165(89)90040-8  0.426
1989 Lázár G, van Galen M, Scherphof GL. Gadolinium chloride-induced shifts in intrahepatic distributions of liposomes. Biochimica Et Biophysica Acta. 1011: 97-101. PMID 2713404 DOI: 10.1016/0167-4889(89)90194-8  0.307
1989 Scherphof GL, Spanjer HH, Derksen JT, Lázár G, Roerdink FH. Targeting of liposomes to liver cells. Horizons in Biochemistry and Biophysics. 9: 281-91. PMID 2656479  0.326
1989 Daemen T, Veninga A, Roerdink FH, Scherphof GL. Endocytic and tumoricidal heterogeneity of rat liver macrophage populations. Selective Cancer Therapeutics. 5: 157-67. PMID 2623381 DOI: 10.1089/Sct.1989.5.157  0.494
1988 Derksen JT, Baldeschwieler JD, Scherphof GL. In vivo stability of ester- and ether-linked phospholipid-containing liposomes as measured by perturbed angular correlation spectroscopy. Proceedings of the National Academy of Sciences of the United States of America. 85: 9768-72. PMID 3200855 DOI: 10.1073/Pnas.85.24.9768  0.49
1988 Derksen JT, Morselt HW, Scherphof GL. Uptake and processing of immunoglobulin-coated liposomes by subpopulations of rat liver macrophages. Biochimica Et Biophysica Acta. 971: 127-36. PMID 2844282 DOI: 10.1016/0167-4889(88)90184-X  0.488
1987 Stegmann T, Morselt HW, Booy FP, van Breemen JF, Scherphof G, Wilschut J. Functional reconstitution of influenza virus envelopes Embo Journal. 6: 2651-2659. PMID 3678202 DOI: 10.1002/J.1460-2075.1987.Tb02556.X  0.315
1987 Kuipers F, Derksen JP, Gerding A, Scherphof GL, Vonk RJ. Biliary lipid secretion in the rat. The uncoupling of biliary cholesterol and phospholipid secretion from bile acid secretion by sulfated glycolithocholic acid. Biochimica Et Biophysica Acta. 922: 136-44. PMID 3676338 DOI: 10.1016/0005-2760(87)90147-0  0.388
1987 Derksen JT, Morselt HW, Scherphof GL. Processing of different liposome markers after in vitro uptake of immunoglobulin-coated liposomes by rat liver macrophages. Biochimica Et Biophysica Acta. 931: 33-40. PMID 3651512 DOI: 10.1016/0167-4889(87)90047-4  0.466
1987 Scherphof GL, Spanjer HH, Derksen JT, Kuipers F, Vonk RJ, Daemen T, Roerdink FH. Delivery of liposome-associated drugs to liver cells. Biochemical Society Transactions. 15: 345-8. PMID 3622912 DOI: 10.1042/Bst0150345  0.407
1987 Derksen JT, Morselt HW, Kalicharan D, Hulstaert CE, Scherphof GL. Interaction of immunoglobulin-coupled liposomes with rat liver macrophages in vitro. Experimental Cell Research. 168: 105-15. PMID 3023116 DOI: 10.1016/0014-4827(87)90420-4  0.479
1987 Scherphof GL, Daemen T, Spanjer HH, Roerdink FH. Liposomes in chemo- and immunotherapy of cancer. Lipids. 22: 891-6. PMID 2965295 DOI: 10.1007/Bf02535550  0.461
1986 Spanjer HH, van Galen M, Roerdink FH, Regts J, Scherphof GL. Intrahepatic distribution of small unilamellar liposomes as a function of liposomal lipid composition. Biochimica Et Biophysica Acta. 863: 224-30. PMID 3790559 DOI: 10.1016/0005-2736(86)90262-2  0.5
1986 Daemen T, Veninga A, Roerdink FH, Scherphof GL. In vitro activation of rat liver macrophages to tumoricidal activity by free or liposome-encapsulated muramyl dipeptide. Cancer Research. 46: 4330-5. PMID 3731091  0.391
1986 Kuipers F, Spanjer HH, Havinga R, Scherphof GL, Vonk RJ. Lipoproteins and liposomes as in vivo cholesterol vehicles in the rat: preferential use of cholesterol carried by small unilamellar liposomes for the formation of muricholic acids. Biochimica Et Biophysica Acta. 876: 559-66. PMID 3707985 DOI: 10.1016/0005-2760(86)90044-5  0.399
1985 Dijkstra J, Galen MV, Regts D, Scherphof G. Uptake and processing of liposomal phospholipids by Kupffer cells in vitro. Febs Journal. 148: 391-397. PMID 3987696 DOI: 10.1111/J.1432-1033.1985.Tb08851.X  0.439
1985 Dijkstra J, Galen Mv, Scherphof G. Effects Of (Dihydro)Cytochalasin-B, Colchicine, Monensin And Trifluoperazine On Uptake And Processing Of Liposomes By Kupffer Cells In Culture Biochimica Et Biophysica Acta. 845: 34-42. PMID 3978127 DOI: 10.1016/0167-4889(85)90051-5  0.424
1985 Dijkstra J, Galen Mv, Scherphof G. Influence of liposome charge on the association of liposomes with Kupffer cells in vitro. Effects of divalent cations and competition with latex particles. Biochimica Et Biophysica Acta. 813: 287-297. PMID 3918567 DOI: 10.1016/0005-2736(85)90244-5  0.384
1985 Spanjer HH, van Berkel TJ, Scherphof GL, Kempen HJ. The effect of a water-soluble tris-galactoside terminated cholesterol derivative on the in vivo fate of small unilamellar vesicles in rats. Biochimica Et Biophysica Acta. 816: 396-402. PMID 3890947 DOI: 10.1016/0005-2736(85)90507-3  0.443
1985 Scherphof GL, Dijkstra J, Spanjer HH, Derksen JT, Roerdink FH. Uptake and intracellular processing of targeted and nontargeted liposomes by rat Kupffer cells in vivo and in vitro. Annals of the New York Academy of Sciences. 446: 368-84. PMID 2409883 DOI: 10.1111/J.1749-6632.1985.Tb18414.X  0.396
1985 Harmsen MC, Wilschut J, Scherphof G, Hulstaert C, Hoekstra D. Reconstitution and fusogenic properties of Sendai virus envelopes Febs Journal. 149: 591-599. PMID 2408889 DOI: 10.1111/J.1432-1033.1985.Tb08966.X  0.302
1984 Spanjer HH, Morselt H, Scherphof GL. Lactosylceramide-induced stimulation of liposome uptake by Kupffer cells in vivo. Biochimica Et Biophysica Acta. 774: 49-55. PMID 6733104 DOI: 10.1016/0005-2736(84)90273-6  0.498
1984 Roerdink FH, Dijkstra J, Spanjer HH, Scherphof GL. Interaction of liposomes with hepatocytes and Kupffer cells in vivo and in vitro. Biochemical Society Transactions. 12: 335-6. PMID 6724117 DOI: 10.1042/Bst0120335  0.379
1984 Dijkstra J, Van Galen M, Scherphof GL. Effects of ammonium chloride and chloroquine on endocytic uptake of liposomes by Kupffer cells in vitro. Biochimica Et Biophysica Acta. 804: 58-67. PMID 6722184 DOI: 10.1016/0167-4889(84)90099-5  0.432
1984 Roerdink F, Regts J, Van Leeuwen B, Scherphof G. Intrahepatic uptake and processing of intravenously injected small unilamellar phospholipid vesicles in rats. Biochimica Et Biophysica Acta. 770: 195-202. PMID 6696907 DOI: 10.1016/0005-2736(84)90130-5  0.463
1984 Dijkstra J, van Galen WJ, Hulstaert CE, Kalicharan D, Roerdink FH, Scherphof GL. Interaction of liposomes with Kupffer cells in vitro. Experimental Cell Research. 150: 161-76. PMID 6692845 DOI: 10.1016/0014-4827(84)90711-0  0.46
1983 Scherphof G, Leeuwen BV, Wilschut J, Damen J. Exchange of phosphatidylcholine between small unilamellar liposomes and human plasma high-density lipoprotein involves exclusively the phospholipid in the outer monolayer of the liposomal membrane Biochimica Et Biophysica Acta. 732: 595-599. PMID 6871217 DOI: 10.1016/0005-2736(83)90236-5  0.36
1983 Soriano P, Dijkstra J, Legrand A, Spanjer H, Londos-Gagliardi D, Roerdink F, Scherphof G, Nicolau C. Targeted and nontargeted liposomes for in vivo transfer to rat liver cells of a plasmid containing the preproinsulin I gene. Proceedings of the National Academy of Sciences of the United States of America. 80: 7128-31. PMID 6580630 DOI: 10.1073/Pnas.80.23.7128  0.468
1983 Hoekstra D, Wilschut J, Scherphof G. Kinetics of calcium phosphate-induced fusion of human erythrocyte ghosts monitored by mixing of aqueous contents. Biochimica Et Biophysica Acta. 732: 327-331. PMID 6409147 DOI: 10.1016/0005-2736(83)90222-5  0.301
1983 Spanjer HH, Scherphof GL. Targeting of lactosylceramide-containing liposomes to hepatocytes in vivo. Biochimica Et Biophysica Acta. 734: 40-7. PMID 6193809 DOI: 10.1016/0005-2736(83)90072-X  0.51
1982 Roerdink F, Dijkstra J, Hartman G, Bolscher B, Scherphof G. The involvement of parenchymal, Kupffer and endothelial liver cells in the hepatic uptake of intravenously injected liposomes. Effects of lanthanum and gadolinium salts. Biochimica Et Biophysica Acta. 677: 79-89. PMID 7295792 DOI: 10.1016/0304-4165(81)90148-3  0.504
1982 Damen J, Regts J, Scherphof G. Transfer of [14C]phosphatidylcholine between liposomes and human plasma high density lipoprotein Partial purification of a transfer-stimulating plasma factor using a rapid transfer assay Biochimica Et Biophysica Acta. 712: 444-452. PMID 7126618 DOI: 10.1016/0005-2760(82)90271-5  0.333
1982 Fonck K, Scherphof GL, Konings AW. The effect of X-irradiation on membrane lipids of lymphosarcoma cells in vivo and in vitro. Journal of Radiation Research. 23: 371-84. PMID 6897658 DOI: 10.1269/Jrr.23.371  0.412
1982 Fonck K, Scherphof GL, Konings AW. Control of fatty acid incorporation in membrane phospholipids. X-ray-induced changes in fatty acid uptake by tumor cells. Biochimica Et Biophysica Acta. 692: 406-14. PMID 6816280 DOI: 10.1016/0005-2736(82)90391-1  0.39
1981 Damen J, Regts J, Scherphof G. Transfer And Exchange Of Phospholipid Between Small Unilamellar Liposomes And Rat Plasma High-Density Lipoproteins - Dependence On Cholesterol Content And Phospholipid-Composition Biochimica Et Biophysica Acta. 665: 538-545. PMID 7295749 DOI: 10.1016/0005-2760(81)90268-X  0.372
1981 Ellens H, Morselt H, Scherphof G. In vivo fate of large unilamellar sphingomyelin-cholesterol liposomes after intraperitoneal and intravenous injection into rats. Biochimica Et Biophysica Acta. 674: 10-8. PMID 7236723 DOI: 10.1016/0304-4165(81)90341-X  0.476
1980 Hoekstra D, Tomasini R, Scherphof G. Interactions of phospholipid vesicles with rat hepatocytes in vitro. Influence of vesicle-incorporated glycolipids Biochimica Et Biophysica Acta. 603: 336-346. PMID 7459359 DOI: 10.1016/0005-2736(80)90379-X  0.442
1980 Damen J, Dijkstra J, Regts J, Scherphof G. Effect of lipoprotein-free plasma on the interaction of human plasma high density lipoprotein with egg yolk phosphatidylcholine liposomes. Biochimica Et Biophysica Acta. 620: 90-99. PMID 7191326 DOI: 10.1016/0005-2760(80)90188-5  0.309
1980 Dijkstra J, Hartman GA, Roerdink FH, Scherphof GL. Uptake of intravenously injected liposomes by parenchymal and non-parenchymal liver cells European Journal of Cell Biology. 22: M655.  0.343
1979 Scherphof G, Morselt H, Regts J, Wilschut JC. The involvement of the lipid phase transition in the plasma-induced dissolution of multilamellar phosphatidylcholine vesicles Biochimica Et Biophysica Acta. 556: 196-207. PMID 534623 DOI: 10.1016/0005-2736(79)90042-7  0.332
1979 van Renswoude AJ, Westenberg P, Scherphof GL. In vitro interaction of Zajdela ascites hepatoma cells with lipid vesicles. Biochimica Et Biophysica Acta. 558: 22-40. PMID 497196 DOI: 10.1016/0005-2736(79)90312-2  0.415
1979 Hoekstra D, Scherphof G. Effect of fetal calf serum and serum protein fractions on the uptake of liposomal phosphatidylcholine by rat hepatocytes in primary monolayer culture. Biochimica Et Biophysica Acta. 551: 109-121. PMID 427147 DOI: 10.1016/0005-2736(79)90357-2  0.447
1978 Hoekstra D, Tomasini R, Scherphof G. Interaction of phospholipid vesicles with rat hepatocytes in primary monolayer culture. Biochimica Et Biophysica Acta. 542: 456-469. PMID 687666 DOI: 10.1016/0304-4165(78)90376-8  0.477
1978 Scherphof G, Roerdink F, Waite M, Parks J. Disintegration of phosphatidylcholine liposomes in plasma as a result of interaction with high-density lipoproteins. Biochimica Et Biophysica Acta. 542: 296-307. PMID 210837 DOI: 10.1016/0304-4165(78)90025-9  0.41
1978 Roerdink FH, Scherphof GL, Wisse E. Cellular distribution in the rat liver of injected liposomal lipid and entrapped proteins: Correlation with the interaction of liposomes with plasma lipoproteins Annals of the New York Academy of Sciences. 433-434.  0.327
1977 Zborowski J, Roerdink F, Scherphof G. Leakage of sucrose from phosphatidylcholine liposomes induced by interaction with serum albumin. Biochimica Et Biophysica Acta. 497: 183-191. PMID 849477 DOI: 10.1016/0304-4165(77)90151-9  0.423
1976 Wilschut JC, Regts J, Westenberg H, Scherphof G. Hydrolysis Of Phosphatidylcholine Liposomes By Phospholipases A2 - Effects Of Local-Anesthetic Dibucaine Biochimica Et Biophysica Acta. 433: 20-31. PMID 1260059 DOI: 10.1016/0005-2736(76)90174-7  0.346
1976 de Goede GW, Samallo J, Holtrop M, Scherphof GL. Lysophospholipase activity in cell-wall fragments contaminating mitochondrial fractions of Neurospora crassa. Biochimica Et Biophysica Acta. 424: 195-203. PMID 3219 DOI: 10.1016/0005-2760(76)90188-0  0.313
1975 Scherphof G, Westenberg H. Stimulation and inhibition of pancreatic phospholipase A2 by local anesthetics as a result of their interaction with the substrate. Biochimica Et Biophysica Acta. 398: 442-451. PMID 240410 DOI: 10.1016/0005-2760(75)90195-2  0.368
1975 Scherphof GL, Roerdink FH, Zborowski J. The use of liposomes to facilitate uptake of external substances by living cells: possible therapeutic applications The Histochemical Journal. 7: 508-510. DOI: 10.1007/Bf01003787  0.33
1974 Wilschut JC, Scherphof GL. The effect of partial degradation of mitochondrial phospholipids by phospholipase A on the temperature dependence of succinate-cytochrome c reductase and cytochrome c oxidase. Biochimica Et Biophysica Acta. 356: 91-9. PMID 4366818 DOI: 10.1016/0005-2736(74)90296-X  0.355
1973 van Schijndel BC, Reitsema A, Scherphof GL. In vitro stimulation of lecithin synthesis in rat liver mitochondria and microsomes after treatment with phospholipase C. Biochemical and Biophysical Research Communications. 55: 568-73. PMID 4202546 DOI: 10.1016/0006-291X(73)91181-9  0.378
1971 Blok MC, Wirtz KW, Scherphof GL. Exchange of phospholipids between microsomes and inner and outer mitochondrial membranes of rat liver. Biochimica Et Biophysica Acta. 233: 61-75. PMID 5579138 DOI: 10.1016/0005-2736(71)90358-0  0.514
1969 van Golde LM, Scherphof GL, van Deenen LL. Biosynthetic pathways in the formation of individual molecular species of rat liver phospholipids. Biochimica Et Biophysica Acta. 176: 635-7. PMID 5800052 DOI: 10.1016/0005-2760(69)90231-8  0.66
1969 Waite M, Scherphof GL, Boshouwers FM, van Deenen LL. Differentiation of phospholipases A in mitochondria and lysosomes of rat liver. Journal of Lipid Research. 10: 411-20. PMID 5797528  0.495
1969 Possmayer F, Scherphof GL, Dubbelman TM, van Golde LM, van Deenen LL. Positional specificity of saturated and unsaturated fatty acids in phosphatidic acid from rat liver. Biochimica Et Biophysica Acta. 176: 95-110. PMID 5766031 DOI: 10.1016/0005-2760(69)90078-2  0.663
1966 Scherphof GL, van Deenen LL. On the pathways of fatty acid incorporation into the lipids of subcellular particles of rat liver and into erythrocytes. Biochimica Et Biophysica Acta. 113: 417-20. PMID 5942444 DOI: 10.1016/S0926-6593(66)80087-5  0.599
1966 Scherphof GL, Waite M, Van Deenen LLM. Formation of lysophosphatidyl ethanolamines in cell fractions of rat liver Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 125: 406-409. DOI: 10.1016/0005-2760(66)90084-1  0.436
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