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Thomas Tuschl, Ph.D. - Publications

Affiliations: 
Molecular Biology Rockefeller University, New York, NY, United States 
Area:
RNAi
Website:
http://www.hhmi.org/research/investigators/tuschl_bio.html

225 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ghisays F, Garzia A, Wang H, Canasto-Chibuque C, Hohl M, Savage SA, Tuschl T, Petrini JHJ. RTEL1 influences the abundance and localization of TERRA RNA. Nature Communications. 12: 3016. PMID 34021146 DOI: 10.1038/s41467-021-23299-2  0.4
2021 Muthukumar T, Akat KM, Yang H, Schwartz JE, Li C, Bang H, Ben-Dov IZ, Lee JR, Ikle D, Demetris AJ, Tuschl T, Suthanthiran M. Serum MicroRNA Transcriptomics and Acute Rejection or Recurrent Hepatitis C Virus in Human Liver Allograft Recipients: A Pilot Study. Transplantation. PMID 33979314 DOI: 10.1097/TP.0000000000003815  0.52
2021 Thrun A, Garzia A, Kigoshi-Tansho Y, Patil PR, Umbaugh CS, Dallinger T, Liu J, Kreger S, Patrizi A, Cox GA, Tuschl T, Joazeiro CAP. Convergence of mammalian RQC and C-end rule proteolytic pathways via alanine tailing. Molecular Cell. PMID 33909987 DOI: 10.1016/j.molcel.2021.03.004  0.4
2021 Sacramento CQ, Fintelman-Rodrigues N, Temerozo JR, Da Silva APD, Dias SDSG, da Silva CDS, Ferreira AC, Mattos M, Pão CRR, de Freitas CS, Soares VC, Hoelz LVB, Fernandes TVA, Branco FSC, Bastos MM, ... ... Tuschl T, et al. In vitro antiviral activity of the anti-HCV drugs daclatasvir and sofosbuvir against SARS-CoV-2, the aetiological agent of COVID-19. The Journal of Antimicrobial Chemotherapy. PMID 33880524 DOI: 10.1093/jac/dkab072  0.4
2020 Wong JJM, Ginter PS, Tyryshkin K, Yang X, Nanayakkara J, Zhou Z, Tuschl T, Chen YT, Renwick N. Classifying Lung Neuroendocrine Neoplasms through MicroRNA Sequence Data Mining. Cancers. 12. PMID 32957587 DOI: 10.3390/Cancers12092653  0.4
2020 Nanayakkara J, Tyryshkin K, Yang X, Wong JJM, Vanderbeck K, Ginter PS, Scognamiglio T, Chen YT, Panarelli N, Cheung NK, Dijk F, Ben-Dov IZ, Kim MK, Singh S, Morozov P, ... ... Tuschl T, et al. Characterizing and classifying neuroendocrine neoplasms through microRNA sequencing and data mining. Nar Cancer. 2: zcaa009. PMID 32743554 DOI: 10.1093/narcan/zcaa009  0.52
2020 Qin LX, Zou J, Shi J, Lee A, Mihailovic A, Farazi TA, Tuschl T, Singer S. Statistical Assessment of Depth Normalization for Small RNA Sequencing. Jco Clinical Cancer Informatics. 4: 567-582. PMID 32598180 DOI: 10.1200/CCI.19.00118  0.52
2020 Stanley S, Vanarsa K, Soliman S, Habazi D, Pedroza C, Gidley G, Zhang T, Mohan S, Der E, Suryawanshi H, Tuschl T, Buyon J, Putterman C, Mok CC, Petri M, et al. Author Correction: Comprehensive aptamer-based screening identifies a spectrum of urinary biomarkers of lupus nephritis across ethnicities. Nature Communications. 11: 3131. PMID 32546742 DOI: 10.1038/S41467-020-16944-9  0.52
2020 Stanley S, Vanarsa K, Soliman S, Habazi D, Pedroza C, Gidley G, Zhang T, Mohan S, Der E, Suryawanshi H, Tuschl T, Buyon J, Putterman C, Mok CC, Petri M, et al. Comprehensive aptamer-based screening identifies a spectrum of urinary biomarkers of lupus nephritis across ethnicities. Nature Communications. 11: 2197. PMID 32366845 DOI: 10.1038/S41467-020-15986-3  0.52
2020 He H, Suryawanshi H, Morozov P, Gay-Mimbrera J, Del Duca E, Kim HJ, Kameyama N, Estrada Y, Der E, Krueger JG, Ruano J, Tuschl T, Guttman-Yassky E. Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis. The Journal of Allergy and Clinical Immunology. PMID 32035984 DOI: 10.1016/J.Jaci.2020.01.042  0.52
2020 Meyer C, Garzia A, Morozov P, Molina H, Tuschl T. The G3BP1-Family-USP10 Deubiquitinase Complex Rescues Ubiquitinated 40S Subunits of Ribosomes Stalled in Translation from Lysosomal Degradation. Molecular Cell. PMID 31981475 DOI: 10.1016/j.molcel.2019.12.024  0.4
2019 Gupta MP, Tandalam S, Ostrager S, Lever AS, Fung AR, Hurley DD, Alegre GB, Espinal JE, Remmel HL, Mukherjee S, Levine BM, Robins RP, Molina H, Dill BD, Kenific CM, ... Tuschl T, et al. Non-reversible tissue fixation retains extracellular vesicles for in situ imaging. Nature Methods. PMID 31712780 DOI: 10.1038/S41592-019-0623-4  0.4
2019 Der E, Suryawanshi H, Morozov P, Kustagi M, Goilav B, Ranabothu S, Izmirly P, Clancy R, Belmont HM, Koenigsberg M, Mokrzycki M, Rominieki H, Graham JA, Rocca JP, Bornkamp N, ... ... Tuschl T, et al. Author Correction: Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways. Nature Immunology. PMID 31605099 DOI: 10.1038/S41590-019-0529-4  0.52
2019 Nikolaou KC, Vatandaslar H, Meyer C, Schmid MW, Tuschl T, Stoffel M. The RNA-Binding Protein A1CF Regulates Hepatic Fructose and Glycerol Metabolism via Alternative RNA Splicing. Cell Reports. 29: 283-300.e8. PMID 31597092 DOI: 10.1016/J.Celrep.2019.08.100  0.4
2019 Suryawanshi H, Clancy R, Morozov P, Halushka MK, Buyon JP, Tuschl T. Cell atlas of the fetal human heart and implications for autoimmune-mediated congenital heart block. Cardiovascular Research. PMID 31589297 DOI: 10.1093/Cvr/Cvz257  0.52
2019 Der E, Suryawanshi H, Buyon J, Tuschl T, Putterman C. Single-cell RNA sequencing for the study of lupus nephritis. Lupus Science & Medicine. 6: e000329. PMID 31245017 DOI: 10.1136/Lupus-2019-000329  0.52
2019 Lama L, Adura C, Xie W, Tomita D, Kamei T, Kuryavyi V, Gogakos T, Steinberg JI, Miller M, Ramos-Espiritu L, Asano Y, Hashizume S, Aida J, Imaeda T, Okamoto R, ... ... Tuschl T, et al. Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression. Nature Communications. 10: 2261. PMID 31113940 DOI: 10.1038/S41467-019-08620-4  0.4
2019 Der E, Suryawanshi H, Morozov P, Kustagi M, Goilav B, Ranabathou S, Izmirly P, Clancy R, Belmont HM, Koenigsberg M, Mokrzycki M, Rominieki H, Graham JA, Rocca JP, Bornkamp N, ... ... Tuschl T, et al. Tubular cell and keratinocyte single-cell transcriptomics applied to lupus nephritis reveal type I IFN and fibrosis relevant pathways. Nature Immunology. PMID 31110316 DOI: 10.1038/S41590-019-0386-1  0.52
2019 Akat KM, Lee YA, Hurley A, Morozov P, Max KE, Brown M, Bogardus K, Sopeyin A, Hildner K, Diacovo TG, Neurath MF, Borggrefe M, Tuschl T. Detection of circulating extracellular mRNAs by modified small-RNA-sequencing analysis. Jci Insight. 5. PMID 30973829 DOI: 10.1172/jci.insight.127317  0.52
2019 Der E, Suryawanshi H, Morozov P, Kustagi M, Goilav B, Ranabothu S, Izmirly P, Clancy R, Belmont M, Koenigsberg M, Mokrzycki M, Rominiecki H, Graham J, Rocca J, Bornkamp N, ... ... Tuschl T, et al. 300 Insights from single-cell RNA sequencing of skin and kidney in lupus nephritis Lupus Science & Medicine. 6. DOI: 10.1136/Lupus-2019-Lsm.300  0.52
2019 Clancy R, Suryawanshi H, Belmont M, Izmirly P, Tuschl T, Buyon J. 194 Transcriptome analysis of skin fibroblasts derived from lupus nephritis patients demonstrates fibrotic and interferon-related cellular biomarkers Lupus Science & Medicine. 6. DOI: 10.1136/Lupus-2019-Lsm.194  0.52
2018 Mukherjee N, Wessels HH, Lebedeva S, Sajek M, Ghanbari M, Garzia A, Munteanu A, Yusuf D, Farazi T, Hoell JI, Akat KM, Akalin A, Tuschl T, Ohler U. Deciphering human ribonucleoprotein regulatory networks. Nucleic Acids Research. PMID 30517751 DOI: 10.1093/Nar/Gky1185  0.4
2018 Suryawanshi H, Morozov P, Straus A, Sahasrabudhe N, Max KEA, Garzia A, Kustagi M, Tuschl T, Williams Z. A single-cell survey of the human first-trimester placenta and decidua. Science Advances. 4: eaau4788. PMID 30402542 DOI: 10.1126/sciadv.aau4788  0.52
2018 Panarelli N, Tyryshkin K, Wong J, Majewski A, Yang X, Scognamiglio T, Kim MK, Bogardus K, Tuschl T, Chen YT, Renwick N. Evaluating gastroenteropancreatic neuroendocrine tumors through microRNA sequencing. Endocrine-Related Cancer. PMID 30021866 DOI: 10.1530/ERC-18-0244  0.4
2018 Watt K, Newsted D, Voorand E, Gooding RJ, Majewski A, Truesdell P, Yao B, Tuschl T, Renwick N, Craig AW. MicroRNA-206 suppresses TGF-β signalling to limit tumor growth and metastasis in lung adenocarcinoma. Cellular Signalling. 50: 25-36. PMID 29935234 DOI: 10.1016/J.Cellsig.2018.06.008  0.4
2018 Max KEA, Bertram K, Akat KM, Bogardus KA, Li J, Morozov P, Ben-Dov IZ, Li X, Weiss ZR, Azizian A, Sopeyin A, Diacovo TG, Adamidi C, Williams Z, Tuschl T. Human plasma and serum extracellular small RNA reference profiles and their clinical utility. Proceedings of the National Academy of Sciences of the United States of America. PMID 29777089 DOI: 10.1073/pnas.1714397115  0.52
2018 Meyer C, Garzia A, Mazzola M, Gerstberger S, Molina H, Tuschl T. The TIA1 RNA-Binding Protein Family Regulates EIF2AK2-Mediated Stress Response and Cell Cycle Progression. Molecular Cell. 69: 622-635.e6. PMID 29429924 DOI: 10.1016/J.Molcel.2018.01.011  0.68
2018 Jafarnejad SM, Chapat C, Matta-Camacho E, Gelbart IA, Hesketh GG, Arguello M, Garzia A, Kim SH, Attig J, Shapiro M, Morita M, Khoutorsky A, Alain T, Gkogkas C, Stern-Ginossar N, ... Tuschl T, et al. Translational control of ERK signaling through miRNA/4EHP-directed silencing. Elife. 7. PMID 29412140 DOI: 10.7554/Elife.35034  0.4
2018 Mok-Lin E, Ascano M, Serganov A, Rosenwaks Z, Tuschl T, Williams Z. Premature recruitment of oocyte pool and increased mTOR activity in Fmr1 knockout mice and reversal of phenotype with rapamycin. Scientific Reports. 8: 588. PMID 29330421 DOI: 10.1038/S41598-017-18598-Y  0.52
2018 Garzia A, Morozov P, Sajek M, Meyer C, Tuschl T. PAR-CLIP for Discovering Target Sites of RNA-Binding Proteins. Methods in Molecular Biology (Clifton, N.J.). 1720: 55-75. PMID 29236251 DOI: 10.1007/978-1-4939-7540-2_5  0.4
2017 Vincent J, Adura C, Gao P, Luz A, Lama L, Asano Y, Okamoto R, Imaeda T, Aida J, Rothamel K, Gogakos T, Steinberg J, Reasoner S, Aso K, Tuschl T, et al. Publisher Correction: Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. Nature Communications. 8: 1827. PMID 29170402 DOI: 10.1038/S41467-017-01770-3  0.52
2017 Gerstberger S, Meyer C, Benjamin-Hong S, Rodriguez J, Briskin D, Bognanni C, Bogardus K, Steller H, Tuschl T. The Conserved RNA Exonuclease Rexo5 Is Required for 3' End Maturation of 28S rRNA, 5S rRNA, and snoRNAs. Cell Reports. 21: 758-772. PMID 29045842 DOI: 10.1016/J.Celrep.2017.09.067  0.68
2017 Vincent J, Adura C, Gao P, Luz A, Lama L, Asano Y, Okamoto R, Imaeda T, Aida J, Rothamel K, Gogakos T, Steinberg J, Reasoner S, Aso K, Tuschl T, et al. Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. Nature Communications. 8: 750. PMID 28963528 DOI: 10.1038/S41467-017-00833-9  0.52
2017 Sheng G, Gogakos T, Wang J, Zhao H, Serganov A, Juranek S, Tuschl T, Patel DJ, Wang Y. Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes. Nucleic Acids Research. 45: 9149-9163. PMID 28911094 DOI: 10.1093/Nar/Gkx547  0.4
2017 Mazzu YZ, Hu Y, Soni RK, Mojica KM, Qin LX, Agius P, Waxman ZM, Mihailovic A, Socci ND, Hendrickson RC, Tuschl T, Singer S. miR-193b-regulated signaling networks serve as tumor suppressors in liposarcoma and promote adipogenesis in adipose-derived stem cells. Cancer Research. PMID 28882999 DOI: 10.1158/0008-5472.Can-16-2253  0.36
2017 Gogakos T, Brown M, Garzia A, Meyer C, Hafner M, Tuschl T. Characterizing Expression and Processing of Precursor and Mature Human tRNAs by Hydro-tRNAseq and PAR-CLIP. Cell Reports. 20: 1463-1475. PMID 28793268 DOI: 10.1016/J.Celrep.2017.07.029  0.68
2017 Garzia A, Jafarnejad SM, Meyer C, Chapat C, Gogakos T, Morozov P, Amiri M, Shapiro M, Molina H, Tuschl T, Sonenberg N. The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs. Nature Communications. 8: 16056. PMID 28685749 DOI: 10.1038/Ncomms16056  0.4
2017 Wang X, Liu H, Ge H, Ajiro M, Sharma NR, Meyers C, Morozov P, Tuschl T, Klar A, Court D, Zheng ZM. Viral DNA Replication Orientation and hnRNPs Regulate Transcription of the Human Papillomavirus 18 Late Promoter. Mbio. 8. PMID 28559488 DOI: 10.1128/Mbio.00713-17  0.4
2017 Der E, Ranabothu S, Suryawanshi H, Akat KM, Clancy R, Morozov P, Kustagi M, Czuppa M, Izmirly P, Belmont HM, Wang T, Jordan N, Bornkamp N, Nwaukoni J, Martinez J, ... ... Tuschl T, et al. Single cell RNA sequencing to dissect the molecular heterogeneity in lupus nephritis. Jci Insight. 2. PMID 28469080 DOI: 10.1172/Jci.Insight.93009  0.52
2017 Yamaji M, Jishage M, Meyer C, Suryawanshi H, Der E, Yamaji M, Garzia A, Morozov P, Manickavel S, McFarland HL, Roeder RG, Hafner M, Tuschl T. DND1 maintains germline stem cells via recruitment of the CCR4-NOT complex to target mRNAs. Nature. PMID 28297718 DOI: 10.1038/Nature21690  0.68
2016 Garzia A, Meyer C, Morozov P, Sajek M, Tuschl T. Optimization of PAR-CLIP for transcriptome-wide identification of binding sites of RNA-binding proteins. Methods (San Diego, Calif.). PMID 27765618 DOI: 10.1016/J.Ymeth.2016.10.007  0.4
2016 Mobin MB, Gerstberger S, Teupser D, Campana B, Charisse K, Heim MH, Manoharan M, Tuschl T, Stoffel M. The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation. Nature Communications. 7: 12848. PMID 27665711 DOI: 10.1038/Ncomms12848  0.68
2016 Meyer C, Garzia A, Tuschl T. Simultaneous detection of the subcellular localization of RNAs and proteins in cultured cells by combined multicolor RNA-FISH and IF. Methods (San Diego, Calif.). PMID 27664292 DOI: 10.1016/J.Ymeth.2016.09.010  0.4
2016 Tu S, Narendra V, Yamaji M, Vidal SE, Rojas LA, Wang X, Kim SY, Garcia BA, Tuschl T, Stadtfeld M, Reinberg D. Co-repressor CBFA2T2 regulates pluripotency and germline development. Nature. PMID 27281218 DOI: 10.1038/Nature18004  1
2016 Ben-Dov IZ, Whalen VM, Goilav B, Max KE, Tuschl T. Cell and Microvesicle Urine microRNA Deep Sequencing Profiles from Healthy Individuals: Observations with Potential Impact on Biomarker Studies. Plos One. 11: e0147249. PMID 26785265 DOI: 10.1371/Journal.Pone.0147249  0.52
2016 Gao P, Ascano M, Zillinger T, Barchet W, Tuschl T, Patel DJ. Abstract B030: Structure-function studies of cytosolic DNA sensing pathway Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-B030  0.52
2015 Williams Z, Morozov P, Mihailovic A, Lin C, Puvvula PK, Juranek S, Rosenwaks Z, Tuschl T. Discovery and Characterization of piRNAs in the Human Fetal Ovary. Cell Reports. 13: 854-63. PMID 26489470 DOI: 10.1016/j.celrep.2015.09.030  1
2015 Hauptmann J, Schraivogel D, Bruckmann A, Manickavel S, Jakob L, Eichner N, Pfaff J, Urban M, Sprunck S, Hafner M, Tuschl T, Deutzmann R, Meister G. Biochemical isolation of Argonaute protein complexes by Ago-APP. Proceedings of the National Academy of Sciences of the United States of America. 112: 11841-5. PMID 26351695 DOI: 10.1073/Pnas.1506116112  0.68
2015 Teplova M, Farazi TA, Tuschl T, Patel DJ. Structural basis underlying CAC RNA recognition by the RRM domain of dimeric RNA-binding protein RBPMS. Quarterly Reviews of Biophysics. 1-11. PMID 26347403 DOI: 10.1017/S0033583515000207  0.52
2015 Yoon JH, Jo MH, White EJ, De S, Hafner M, Zucconi BE, Abdelmohsen K, Martindale JL, Yang X, Wood WH, Shin YM, Song JJ, Tuschl T, Becker KG, Wilson GM, et al. AUF1 promotes let-7b loading on Argonaute 2. Genes & Development. 29: 1599-604. PMID 26253535 DOI: 10.1101/Gad.263749.115  0.68
2015 Gulati N, Løvendorf MB, Zibert JR, Akat KM, Renwick N, Tuschl T, Krueger JG. Unique microRNAs appear at different times during the course of a delayed-type hypersensitivity reaction in human skin. Experimental Dermatology. PMID 26205579 DOI: 10.1111/Exd.12813  0.4
2015 Latreille M, Herrmanns K, Renwick N, Tuschl T, Malecki MT, McCarthy MI, Owen KR, Rülicke T, Stoffel M. miR-375 gene dosage in pancreatic β-cells: implications for regulation of β-cell mass and biomarker development. Journal of Molecular Medicine (Berlin, Germany). PMID 26013143 DOI: 10.1007/S00109-015-1296-9  1
2015 Anchan R, Gerami-Naini B, Lindsey JS, Ho JW, Kiezun A, Lipskind S, Ng N, LiCausi JA, Kim CS, Brezina P, Tuschl T, Maas R, Kearns WG, Williams Z. Efficient differentiation of steroidogenic and germ-like cells from epigenetically-related iPSCs derived from ovarian granulosa cells. Plos One. 10: e0119275. PMID 25751620 DOI: 10.1371/Journal.Pone.0119275  1
2015 Santa-Maria I, Alaniz ME, Renwick N, Cela C, Fulga TA, Van Vactor D, Tuschl T, Clark LN, Shelanski ML, McCabe BD, Crary JF. Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau. The Journal of Clinical Investigation. 125: 681-6. PMID 25574843 DOI: 10.1172/Jci78421  0.4
2015 La Rocca G, Olejniczak SH, González AJ, Briskin D, Vidigal JA, Spraggon L, DeMatteo RG, Radler MR, Lindsten T, Ventura A, Tuschl T, Leslie CS, Thompson CB. In vivo, Argonaute-bound microRNAs exist predominantly in a reservoir of low molecular weight complexes not associated with mRNA. Proceedings of the National Academy of Sciences of the United States of America. 112: 767-72. PMID 25568082 DOI: 10.1073/Pnas.1424217112  1
2015 Lai JY, Luo J, O'Connor C, Jing X, Nair V, Ju W, Randolph A, Ben-Dov IZ, Matar RN, Briskin D, Zavadil J, Nelson RG, Tuschl T, Brosius FC, Kretzler M, et al. MicroRNA-21 in glomerular injury. Journal of the American Society of Nephrology : Jasn. 26: 805-16. PMID 25145934 DOI: 10.1681/Asn.2013121274  1
2014 Lu YC, Chang SH, Hafner M, Li X, Tuschl T, Elemento O, Hla T. ELAVL1 modulates transcriptome-wide miRNA binding in murine macrophages. Cell Reports. 9: 2330-43. PMID 25533351 DOI: 10.1016/J.Celrep.2014.11.030  1
2014 Yoon JH, De S, Srikantan S, Abdelmohsen K, Grammatikakis I, Kim J, Kim KM, Noh JH, White EJ, Martindale JL, Yang X, Kang MJ, Wood WH, Noren Hooten N, Evans MK, ... ... Tuschl T, et al. PAR-CLIP analysis uncovers AUF1 impact on target RNA fate and genome integrity. Nature Communications. 5: 5248. PMID 25366541 DOI: 10.1038/Ncomms6248  0.68
2014 Gerstberger S, Hafner M, Tuschl T. A census of human RNA-binding proteins. Nature Reviews. Genetics. 15: 829-45. PMID 25365966 DOI: 10.1038/Nrg3813  1
2014 Renwick N, Cekan P, Bognanni C, Tuschl T. Multiplexed miRNA fluorescence in situ hybridization for formalin-fixed paraffin-embedded tissues. Methods in Molecular Biology (Clifton, N.J.). 1211: 171-87. PMID 25218385 DOI: 10.1007/978-1-4939-1459-3_14  1
2014 Gerstberger S, Hafner M, Ascano M, Tuschl T. Evolutionary conservation and expression of human RNA-binding proteins and their role in human genetic disease. Advances in Experimental Medicine and Biology. 825: 1-55. PMID 25201102 DOI: 10.1007/978-1-4939-1221-6_1  1
2014 Gao P, Zillinger T, Wang W, Ascano M, Dai P, Hartmann G, Tuschl T, Deng L, Barchet W, Patel DJ. Binding-pocket and lid-region substitutions render human STING sensitive to the species-specific drug DMXAA. Cell Reports. 8: 1668-76. PMID 25199835 DOI: 10.1016/J.Celrep.2014.08.010  1
2014 Santulli G, Wronska A, Uryu K, Diacovo TG, Gao M, Marx SO, Kitajewski J, Chilton JM, Akat KM, Tuschl T, Marks AR, Totary-Jain H. A selective microRNA-based strategy inhibits restenosis while preserving endothelial function. The Journal of Clinical Investigation. 124: 4102-14. PMID 25133430 DOI: 10.1172/Jci76069  1
2014 Akat KM, Moore-McGriff D, Morozov P, Brown M, Gogakos T, Correa Da Rosa J, Mihailovic A, Sauer M, Ji R, Ramarathnam A, Totary-Jain H, Williams Z, Tuschl T, Schulze PC. Comparative RNA-sequencing analysis of myocardial and circulating small RNAs in human heart failure and their utility as biomarkers. Proceedings of the National Academy of Sciences of the United States of America. 111: 11151-6. PMID 25012294 DOI: 10.1073/Pnas.1401724111  1
2014 Cheung IY, Farazi TA, Ostrovnaya I, Xu H, Tran H, Mihailovic A, Tuschl T, Cheung NK. Deep MicroRNA sequencing reveals downregulation of miR-29a in neuroblastoma central nervous system metastasis. Genes, Chromosomes & Cancer. 53: 803-14. PMID 24898736 DOI: 10.1002/Gcc.22189  1
2014 Farazi TA, Leonhardt CS, Mukherjee N, Mihailovic A, Li S, Max KE, Meyer C, Yamaji M, Cekan P, Jacobs NC, Gerstberger S, Bognanni C, Larsson E, Ohler U, Tuschl T. Identification of the RNA recognition element of the RBPMS family of RNA-binding proteins and their transcriptome-wide mRNA targets. Rna (New York, N.Y.). 20: 1090-102. PMID 24860013 DOI: 10.1261/Rna.045005.114  1
2014 Karaca E, Weitzer S, Pehlivan D, Shiraishi H, Gogakos T, Hanada T, Jhangiani SN, Wiszniewski W, Withers M, Campbell IM, Erdin S, Isikay S, Franco LM, Gonzaga-Jauregui C, Gambin T, ... ... Tuschl T, et al. Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function. Cell. 157: 636-50. PMID 24766809 DOI: 10.1016/J.Cell.2014.02.058  1
2014 Goldeck M, Tuschl T, Hartmann G, Ludwig J. Efficient solid-phase synthesis of pppRNA by using product-specific labeling. Angewandte Chemie (International Ed. in English). 53: 4694-8. PMID 24668741 DOI: 10.1002/Anie.201400672  1
2014 Wang X, Wang HK, Li Y, Hafner M, Banerjee NS, Tang S, Briskin D, Meyers C, Chow LT, Xie X, Tuschl T, Zheng ZM. microRNAs are biomarkers of oncogenic human papillomavirus infections. Proceedings of the National Academy of Sciences of the United States of America. 111: 4262-7. PMID 24591631 DOI: 10.1073/Pnas.1401430111  1
2014 Spitzer J, Hafner M, Landthaler M, Ascano M, Farazi T, Wardle G, Nusbaum J, Khorshid M, Burger L, Zavolan M, Tuschl T. PAR-CLIP (Photoactivatable Ribonucleoside-Enhanced Crosslinking and Immunoprecipitation): a step-by-step protocol to the transcriptome-wide identification of binding sites of RNA-binding proteins. Methods in Enzymology. 539: 113-61. PMID 24581442 DOI: 10.1016/B978-0-12-420120-0.00008-6  1
2014 Ben-Dov IZ, Tan YC, Morozov P, Wilson PD, Rennert H, Blumenfeld JD, Tuschl T. Urine microRNA as potential biomarkers of autosomal dominant polycystic kidney disease progression: description of miRNA profiles at baseline. Plos One. 9: e86856. PMID 24489795 DOI: 10.1371/Journal.Pone.0086856  1
2014 Prosdocimo DA, Anand P, Liao X, Zhu H, Shelkay S, Artero-Calderon P, Zhang L, Kirsh J, Moore D, Rosca MG, Vazquez E, Kerner J, Akat KM, Williams Z, Zhao J, ... ... Tuschl T, et al. Kruppel-like factor 15 is a critical regulator of cardiac lipid metabolism. The Journal of Biological Chemistry. 289: 5914-24. PMID 24407292 DOI: 10.1074/Jbc.M113.531384  1
2014 Mukherjee N, Jacobs NC, Hafner M, Kennington EA, Nusbaum JD, Tuschl T, Blackshear PJ, Ohler U. Global target mRNA specification and regulation by the RNA-binding protein ZFP36. Genome Biology. 15: R12. PMID 24401661 DOI: 10.1186/Gb-2014-15-1-R12  1
2014 Farazi TA, Ten Hoeve JJ, Brown M, Mihailovic A, Horlings HM, van de Vijver MJ, Tuschl T, Wessels LF. Identification of distinct miRNA target regulation between breast cancer molecular subtypes using AGO2-PAR-CLIP and patient datasets. Genome Biology. 15: R9. PMID 24398324 DOI: 10.1186/Gb-2014-15-1-R9  1
2014 Farazi TA, Leonhardt CS, Tuschl T. MicroRNA expression in breast cancer revealed by deep sequencing technology Next Generation Sequencing in Cancer Research. 1: 233-261. DOI: 10.1007/978-1-4614-7645-0_12  1
2013 Spitzer J, Landthaler M, Tuschl T. Rapid creation of stable mammalian cell lines for regulated expression of proteins using the Gateway® recombination cloning technology and Flp-In T-REx® lines. Methods in Enzymology. 529: 99-124. PMID 24011039 DOI: 10.1016/B978-0-12-418687-3.00008-2  1
2013 Mosquera JM, Sboner A, Zhang L, Chen CL, Sung YS, Chen HW, Agaram NP, Briskin D, Basha BM, Singer S, Rubin MA, Tuschl T, Antonescu CR. Novel MIR143-NOTCH fusions in benign and malignant glomus tumors. Genes, Chromosomes & Cancer. 52: 1075-87. PMID 23999936 DOI: 10.1002/Gcc.22102  1
2013 Gerstberger S, Hafner M, Tuschl T. Learning the language of post-transcriptional gene regulation. Genome Biology. 14: 130. PMID 23998708 DOI: 10.1186/Gb-2013-14-8-130  1
2013 Brown M, Suryawanshi H, Hafner M, Farazi TA, Tuschl T. Mammalian miRNA curation through next-generation sequencing. Frontiers in Genetics. 4: 145. PMID 23935604 DOI: 10.3389/Fgene.2013.00145  1
2013 Gao P, Ascano M, Zillinger T, Wang W, Dai P, Serganov AA, Gaffney BL, Shuman S, Jones RA, Deng L, Hartmann G, Barchet W, Tuschl T, Patel DJ. Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA. Cell. 154: 748-62. PMID 23910378 DOI: 10.1016/J.Cell.2013.07.023  1
2013 Nakanishi K, Ascano M, Gogakos T, Ishibe-Murakami S, Serganov AA, Briskin D, Morozov P, Tuschl T, Patel DJ. Eukaryote-specific insertion elements control human ARGONAUTE slicer activity. Cell Reports. 3: 1893-900. PMID 23809764 DOI: 10.1016/J.Celrep.2013.06.010  1
2013 Renwick N, Cekan P, Masry PA, McGeary SE, Miller JB, Hafner M, Li Z, Mihailovic A, Morozov P, Brown M, Gogakos T, Mobin MB, Snorrason EL, Feilotter HE, Zhang X, ... ... Tuschl T, et al. Multicolor microRNA FISH effectively differentiates tumor types. The Journal of Clinical Investigation. 123: 2694-702. PMID 23728175 DOI: 10.1172/Jci68760  1
2013 Fritz EL, Rosenberg BR, Lay K, Mihailovi? A, Tuschl T, Papavasiliou FN. A comprehensive analysis of the effects of the deaminase AID on the transcriptome and methylome of activated B cells. Nature Immunology. 14: 749-55. PMID 23708250 DOI: 10.1038/Ni.2616  1
2013 Gao P, Ascano M, Wu Y, Barchet W, Gaffney BL, Zillinger T, Serganov AA, Liu Y, Jones RA, Hartmann G, Tuschl T, Patel DJ. Cyclic [G(2',5')pA(3',5')p] is the metazoan second messenger produced by DNA-activated cyclic GMP-AMP synthase. Cell. 153: 1094-107. PMID 23647843 DOI: 10.1016/J.Cell.2013.04.046  1
2013 Teplova M, Hafner M, Teplov D, Essig K, Tuschl T, Patel DJ. Structure-function studies of STAR family Quaking proteins bound to their in vivo RNA target sites. Genes & Development. 27: 928-40. PMID 23630077 DOI: 10.1101/Gad.216531.113  1
2013 Qin LX, Tuschl T, Singer S. An Empirical Evaluation of Normalization Methods for MicroRNA Arrays in a Liposarcoma Study. Cancer Informatics. 12: 83-101. PMID 23589668 DOI: 10.4137/CIN.S11384  1
2013 Hafner M, Max KE, Bandaru P, Morozov P, Gerstberger S, Brown M, Molina H, Tuschl T. Identification of mRNAs bound and regulated by human LIN28 proteins and molecular requirements for RNA recognition. Rna (New York, N.Y.). 19: 613-26. PMID 23481595 DOI: 10.1261/Rna.036491.112  1
2013 Ascano M, Gerstberger S, Tuschl T. Multi-disciplinary methods to define RNA-protein interactions and regulatory networks. Current Opinion in Genetics & Development. 23: 20-8. PMID 23453689 DOI: 10.1016/J.Gde.2013.01.003  1
2013 Williams Z, Ben-Dov IZ, Elias R, Mihailovic A, Brown M, Rosenwaks Z, Tuschl T. Comprehensive profiling of circulating microRNA via small RNA sequencing of cDNA libraries reveals biomarker potential and limitations. Proceedings of the National Academy of Sciences of the United States of America. 110: 4255-60. PMID 23440203 DOI: 10.1073/Pnas.1214046110  1
2013 Trompeter HI, Dreesen J, Hermann E, Iwaniuk KM, Hafner M, Renwick N, Tuschl T, Wernet P. MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood. Bmc Genomics. 14: 111. PMID 23418963 DOI: 10.1186/1471-2164-14-111  1
2013 Farazi TA, Hoell JI, Morozov P, Tuschl T. MicroRNAs in human cancer. Advances in Experimental Medicine and Biology. 774: 1-20. PMID 23377965 DOI: 10.1007/978-94-007-5590-1_1  1
2013 Totary-Jain H, Sanoudou D, Ben-Dov IZ, Dautriche CN, Guarnieri P, Marx SO, Tuschl T, Marks AR. Reprogramming of the microRNA transcriptome mediates resistance to rapamycin. The Journal of Biological Chemistry. 288: 6034-44. PMID 23300087 DOI: 10.1074/Jbc.M112.416446  1
2013 John B, Enright AJ, Aravin A, Tuschl T, Sander C, Marks DS. Potential miRNA Target Sites in the 3′ UTRs of Selected Genes Plos Biology. DOI: 10.1371/Journal.Pbio.0020363.G004  0.36
2013 Mok-Lin E, Ascano M, Rosenwaks Z, Tuschl T, Williams Z. A mouse model for fragile X- associated primary ovarian insufficiency Fertility and Sterility. 100. DOI: 10.1016/J.Fertnstert.2013.07.1841  0.52
2012 Luo GZ, Hafner M, Shi Z, Brown M, Feng GH, Tuschl T, Wang XJ, Li X. Genome-wide annotation and analysis of zebra finch microRNA repertoire reveal sex-biased expression. Bmc Genomics. 13: 727. PMID 23268654 DOI: 10.1186/1471-2164-13-727  1
2012 Ascano M, Mukherjee N, Bandaru P, Miller JB, Nusbaum JD, Corcoran DL, Langlois C, Munschauer M, Dewell S, Hafner M, Williams Z, Ohler U, Tuschl T. FMRP targets distinct mRNA sequence elements to regulate protein expression. Nature. 492: 382-6. PMID 23235829 DOI: 10.1038/Nature11737  1
2012 Ben-Dov IZ, Muthukumar T, Morozov P, Mueller FB, Tuschl T, Suthanthiran M. MicroRNA sequence profiles of human kidney allografts with or without tubulointerstitial fibrosis. Transplantation. 94: 1086-94. PMID 23131772 DOI: 10.1097/Tp.0B013E3182751Efd  1
2012 Hafner M, Lianoglou S, Tuschl T, Betel D. Genome-wide identification of miRNA targets by PAR-CLIP. Methods (San Diego, Calif.). 58: 94-105. PMID 22926237 DOI: 10.1016/J.Ymeth.2012.08.006  1
2012 Hafner M, Renwick N, Farazi TA, Mihailovi? A, Pena JT, Tuschl T. Barcoded cDNA library preparation for small RNA profiling by next-generation sequencing. Methods (San Diego, Calif.). 58: 164-70. PMID 22885844 DOI: 10.1016/J.Ymeth.2012.07.030  1
2012 Scheibe M, Butter F, Hafner M, Tuschl T, Mann M. Quantitative mass spectrometry and PAR-CLIP to identify RNA-protein interactions. Nucleic Acids Research. 40: 9897-902. PMID 22885304 DOI: 10.1093/Nar/Gks746  1
2012 Farazi TA, Brown M, Morozov P, Ten Hoeve JJ, Ben-Dov IZ, Hovestadt V, Hafner M, Renwick N, Mihailovi? A, Wessels LF, Tuschl T. Bioinformatic analysis of barcoded cDNA libraries for small RNA profiling by next-generation sequencing. Methods (San Diego, Calif.). 58: 171-87. PMID 22836126 DOI: 10.1016/J.Ymeth.2012.07.020  1
2012 Rajasethupathy P, Antonov I, Sheridan R, Frey S, Sander C, Tuschl T, Kandel ER. A role for neuronal piRNAs in the epigenetic control of memory-related synaptic plasticity. Cell. 149: 693-707. PMID 22541438 DOI: 10.1016/J.Cell.2012.02.057  1
2012 Italiano A, Thomas R, Breen M, Zhang L, Crago AM, Singer S, Khanin R, Maki RG, Mihailovic A, Hafner M, Tuschl T, Antonescu CR. The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification. Genes, Chromosomes & Cancer. 51: 569-78. PMID 22383169 DOI: 10.1002/Gcc.21943  1
2012 Juranek S, Eban T, Altuvia Y, Brown M, Morozov P, Tuschl T, Margalit H. A genome-wide view of the expression and processing patterns of Thermus thermophilus HB8 CRISPR RNAs. Rna (New York, N.Y.). 18: 783-94. PMID 22355165 DOI: 10.1261/Rna.031468.111  1
2012 Skalsky RL, Corcoran DL, Gottwein E, Frank CL, Kang D, Hafner M, Nusbaum JD, Feederle R, Delecluse HJ, Luftig MA, Tuschl T, Ohler U, Cullen BR. The viral and cellular microRNA targetome in lymphoblastoid cell lines. Plos Pathogens. 8: e1002484. PMID 22291592 DOI: 10.1371/Journal.Ppat.1002484  1
2012 Ascano M, Hafner M, Cekan P, Gerstberger S, Tuschl T. Identification of RNA-protein interaction networks using PAR-CLIP. Wiley Interdisciplinary Reviews. Rna. 3: 159-77. PMID 22213601 DOI: 10.1002/Wrna.1103  1
2011 Gottwein E, Corcoran DL, Mukherjee N, Skalsky RL, Hafner M, Nusbaum JD, Shamulailatpam P, Love CL, Dave SS, Tuschl T, Ohler U, Cullen BR. Viral microRNA targetome of KSHV-infected primary effusion lymphoma cell lines. Cell Host & Microbe. 10: 515-26. PMID 22100165 DOI: 10.1016/J.Chom.2011.09.012  1
2011 Hoell JI, Larsson E, Runge S, Nusbaum JD, Duggimpudi S, Farazi TA, Hafner M, Borkhardt A, Sander C, Tuschl T. RNA targets of wild-type and mutant FET family proteins. Nature Structural & Molecular Biology. 18: 1428-31. PMID 22081015 DOI: 10.1038/Nsmb.2163  1
2011 Hafner M, Ascano M, Tuschl T. New insights in the mechanism of microRNA-mediated target repression. Nature Structural & Molecular Biology. 18: 1181-2. PMID 22056803 DOI: 10.1038/Nsmb.2170  1
2011 Lipchina I, Elkabetz Y, Hafner M, Sheridan R, Mihailovic A, Tuschl T, Sander C, Studer L, Betel D. Genome-wide identification of microRNA targets in human ES cells reveals a role for miR-302 in modulating BMP response. Genes & Development. 25: 2173-86. PMID 22012620 DOI: 10.1101/Gad.17221311  1
2011 Zhang X, Yalcin S, Lee DF, Yeh TY, Lee SM, Su J, Mungamuri SK, Rimmelé P, Kennedy M, Sellers R, Landthaler M, Tuschl T, Chi NW, Lemischka I, Keller G, et al. FOXO1 is an essential regulator of pluripotency in human embryonic stem cells. Nature Cell Biology. 13: 1092-9. PMID 21804543 DOI: 10.1038/Ncb2293  1
2011 Fiedler J, Jazbutyte V, Kirchmaier BC, Gupta SK, Lorenzen J, Hartmann D, Galuppo P, Kneitz S, Pena JT, Sohn-Lee C, Loyer X, Soutschek J, Brand T, Tuschl T, Heineke J, et al. MicroRNA-24 regulates vascularity after myocardial infarction. Circulation. 124: 720-30. PMID 21788589 DOI: 10.1161/Circulationaha.111.039008  1
2011 Hafner M, Renwick N, Brown M, Mihailovi? A, Holoch D, Lin C, Pena JT, Nusbaum JD, Morozov P, Ludwig J, Ojo T, Luo S, Schroth G, Tuschl T. RNA-ligase-dependent biases in miRNA representation in deep-sequenced small RNA cDNA libraries. Rna (New York, N.Y.). 17: 1697-712. PMID 21775473 DOI: 10.1261/Rna.2799511  1
2011 Mukherjee N, Corcoran DL, Nusbaum JD, Reid DW, Georgiev S, Hafner M, Ascano M, Tuschl T, Ohler U, Keene JD. Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability. Molecular Cell. 43: 327-39. PMID 21723170 DOI: 10.1016/J.Molcel.2011.06.007  1
2011 Ugras S, Brill E, Jacobsen A, Hafner M, Socci ND, Decarolis PL, Khanin R, O'Connor R, Mihailovic A, Taylor BS, Sheridan R, Gimble JM, Viale A, Crago A, Antonescu CR, ... ... Tuschl T, et al. Small RNA sequencing and functional characterization reveals MicroRNA-143 tumor suppressor activity in liposarcoma. Cancer Research. 71: 5659-69. PMID 21693658 DOI: 10.1158/0008-5472.Can-11-0890  1
2011 Farazi TA, Horlings HM, Ten Hoeve JJ, Mihailovic A, Halfwerk H, Morozov P, Brown M, Hafner M, Reyal F, van Kouwenhove M, Kreike B, Sie D, Hovestadt V, Wessels LF, van de Vijver MJ, ... Tuschl T, et al. MicroRNA sequence and expression analysis in breast tumors by deep sequencing. Cancer Research. 71: 4443-53. PMID 21586611 DOI: 10.1158/0008-5472.Can-11-0608  1
2011 Tian Y, Simanshu DK, Ascano M, Diaz-Avalos R, Park AY, Juranek SA, Rice WJ, Yin Q, Robinson CV, Tuschl T, Patel DJ. Multimeric assembly and biochemical characterization of the Trax-translin endonuclease complex. Nature Structural & Molecular Biology. 18: 658-64. PMID 21552261 DOI: 10.1038/Nsmb.2069  1
2011 Wang H, Zhang X, Liu J, Kiba T, Woo J, Ojo T, Hafner M, Tuschl T, Chua NH, Wang XJ. Deep sequencing of small RNAs specifically associated with Arabidopsis AGO1 and AGO4 uncovers new AGO functions. The Plant Journal : For Cell and Molecular Biology. 67: 292-304. PMID 21457371 DOI: 10.1111/J.1365-313X.2011.04594.X  1
2011 Bissels U, Wild S, Tomiuk S, Hafner M, Scheel H, Mihailovic A, Choi YH, Tuschl T, Bosio A. Combined characterization of microRNA and mRNA profiles delineates early differentiation pathways of CD133+ and CD34+ hematopoietic stem and progenitor cells. Stem Cells (Dayton, Ohio). 29: 847-57. PMID 21394831 DOI: 10.1002/Stem.627  1
2011 Spitzer JI, Ugras S, Runge S, Decarolis P, Antonescu C, Tuschl T, Singer S. mRNA and protein levels of FUS, EWSR1, and TAF15 are upregulated in liposarcoma. Genes, Chromosomes & Cancer. 50: 338-47. PMID 21344536 DOI: 10.1002/gcc.20858  1
2011 Trompeter HI, Abbad H, Iwaniuk KM, Hafner M, Renwick N, Tuschl T, Schira J, Müller HW, Wernet P. MicroRNAs MiR-17, MiR-20a, and MiR-106b act in concert to modulate E2F activity on cell cycle arrest during neuronal lineage differentiation of USSC. Plos One. 6: e16138. PMID 21283765 DOI: 10.1371/Journal.Pone.0016138  1
2011 Farazi TA, Spitzer JI, Morozov P, Tuschl T. miRNAs in human cancer. The Journal of Pathology. 223: 102-15. PMID 21125669 DOI: 10.1002/Path.2806  1
2011 Ben-Dov IZ, Brown M, Whalen VM, Tuschl T. 30 Profiling Urine Cell and Exosome Microrna Using a Barcoded Small RNA Deep Sequencing Approach American Journal of Kidney Diseases. 57. DOI: 10.1053/J.Ajkd.2011.02.033  0.52
2010 Hafner M, Landthaler M, Burger L, Khorshid M, Hausser J, Berninger P, Rothballer A, Ascano M, Jungkamp AC, Munschauer M, Ulrich A, Wardle GS, Dewell S, Zavolan M, Tuschl T. PAR-CliP--a method to identify transcriptome-wide the binding sites of RNA binding proteins. Journal of Visualized Experiments : Jove. PMID 20644507 DOI: 10.3791/2034  1
2010 Wang Y, Ludwig J, Schuberth C, Goldeck M, Schlee M, Li H, Juranek S, Sheng G, Micura R, Tuschl T, Hartmann G, Patel DJ. Structural and functional insights into 5'-ppp RNA pattern recognition by the innate immune receptor RIG-I. Nature Structural & Molecular Biology. 17: 781-7. PMID 20581823 DOI: 10.1038/Nsmb.1863  1
2010 Wibrand K, Panja D, Tiron A, Ofte ML, Skaftnesmo KO, Lee CS, Pena JT, Tuschl T, Bramham CR. Differential regulation of mature and precursor microRNA expression by NMDA and metabotropic glutamate receptor activation during LTP in the adult dentate gyrus in vivo. The European Journal of Neuroscience. 31: 636-45. PMID 20384810 DOI: 10.1111/J.1460-9568.2010.07112.X  1
2010 Hafner M, Landthaler M, Burger L, Khorshid M, Hausser J, Berninger P, Rothballer A, Ascano M, Jungkamp AC, Munschauer M, Ulrich A, Wardle GS, Dewell S, Zavolan M, Tuschl T. Transcriptome-wide identification of RNA-binding protein and microRNA target sites by PAR-CLIP. Cell. 141: 129-41. PMID 20371350 DOI: 10.1016/J.Cell.2010.03.009  1
2010 Angeles CV, Hafner M, Socci ND, DeCarolis P, Tuschl T, Singer S. Abstract 3100: The RNA-binding protein insulin-like growth factor 2 mRNA-binding protein 3 is oncogenic in liposarcoma Cancer Research. 70: 3100-3100. DOI: 10.1158/1538-7445.Am10-3100  0.68
2009 Bissels U, Wild S, Tomiuk S, Holste A, Hafner M, Tuschl T, Bosio A. Absolute quantification of microRNAs by using a universal reference. Rna (New York, N.Y.). 15: 2375-84. PMID 19861428 DOI: 10.1261/Rna.1754109  1
2009 Wang Y, Juranek S, Li H, Sheng G, Wardle GS, Tuschl T, Patel DJ. Nucleation, propagation and cleavage of target RNAs in Ago silencing complexes. Nature. 461: 754-61. PMID 19812667 DOI: 10.1038/Nature08434  1
2009 Rajasethupathy P, Fiumara F, Sheridan R, Betel D, Puthanveettil SV, Russo JJ, Sander C, Tuschl T, Kandel E. Characterization of small RNAs in Aplysia reveals a role for miR-124 in constraining synaptic plasticity through CREB. Neuron. 63: 803-17. PMID 19778509 DOI: 10.1016/J.Neuron.2009.05.029  1
2009 Taulli R, Bersani F, Foglizzo V, Linari A, Vigna E, Ladanyi M, Tuschl T, Ponzetto C. The muscle-specific microRNA miR-206 blocks human rhabdomyosarcoma growth in xenotransplanted mice by promoting myogenic differentiation. The Journal of Clinical Investigation. 119: 2366-78. PMID 19620785 DOI: 10.1172/Jci38075  1
2009 Schlee M, Roth A, Hornung V, Hagmann CA, Wimmenauer V, Barchet W, Coch C, Janke M, Mihailovic A, Wardle G, Juranek S, Kato H, Kawai T, Poeck H, Fitzgerald KA, ... ... Tuschl T, et al. Recognition of 5' triphosphate by RIG-I helicase requires short blunt double-stranded RNA as contained in panhandle of negative-strand virus. Immunity. 31: 25-34. PMID 19576794 DOI: 10.1016/J.Immuni.2009.05.008  1
2009 Huse JT, Brennan C, Hambardzumyan D, Wee B, Pena J, Rouhanifard SH, Sohn-Lee C, le Sage C, Agami R, Tuschl T, Holland EC. The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo. Genes & Development. 23: 1327-37. PMID 19487573 DOI: 10.1101/Gad.1777409  1
2009 Pena JT, Sohn-Lee C, Rouhanifard SH, Ludwig J, Hafner M, Mihailovic A, Lim C, Holoch D, Berninger P, Zavolan M, Tuschl T. miRNA in situ hybridization in formaldehyde and EDC-fixed tissues. Nature Methods. 6: 139-41. PMID 19137005 DOI: 10.1038/Nmeth.1294  1
2009 Yi R, Pasolli HA, Landthaler M, Hafner M, Ojo T, Sheridan R, Sander C, O'Carroll D, Stoffel M, Tuschl T, Fuchs E. DGCR8-dependent microRNA biogenesis is essential for skin development. Proceedings of the National Academy of Sciences of the United States of America. 106: 498-502. PMID 19114655 DOI: 10.1073/Pnas.0810766105  1
2009 Martin R, Smibert P, Yalcin A, Tyler DM, Schäfer U, Tuschl T, Lai EC. A Drosophila pasha mutant distinguishes the canonical microRNA and mirtron pathways. Molecular and Cellular Biology. 29: 861-70. PMID 19047376 DOI: 10.1128/Mcb.01524-08  1
2009 Zhang Y, Landthaler M, Schlussman SD, Yuferov V, Ho A, Tuschl T, Kreek MJ. Mu opioid receptor knockdown in the substantia nigra/ventral tegmental area by synthetic small interfering RNA blocks the rewarding and locomotor effects of heroin. Neuroscience. 158: 474-83. PMID 18938225 DOI: 10.1016/J.Neuroscience.2008.09.039  1
2009 MAJ, Landthaler M, Khorshid M, Burger L, Hafner M, Zavolan M, Tuschl T. Transcriptome-wide Identification of the mRNA target sites of the Fragile-X Mental Retardation Proteins The Faseb Journal. 23. DOI: 10.1096/Fasebj.23.1_Supplement.666.2  0.68
2008 Wang Y, Juranek S, Li H, Sheng G, Tuschl T, Patel DJ. Structure of an argonaute silencing complex with a seed-containing guide DNA and target RNA duplex. Nature. 456: 921-6. PMID 19092929 DOI: 10.1038/Nature07666  1
2008 Thum T, Gross C, Fiedler J, Fischer T, Kissler S, Bussen M, Galuppo P, Just S, Rottbauer W, Frantz S, Castoldi M, Soutschek J, Koteliansky V, Rosenwald A, Basson MA, ... ... Tuschl T, et al. MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature. 456: 980-4. PMID 19043405 DOI: 10.1038/Nature07511  1
2008 Landthaler M, Gaidatzis D, Rothballer A, Chen PY, Soll SJ, Dinic L, Ojo T, Hafner M, Zavolan M, Tuschl T. Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs. Rna (New York, N.Y.). 14: 2580-96. PMID 18978028 DOI: 10.1261/Rna.1351608  1
2008 Wang Y, Sheng G, Juranek S, Tuschl T, Patel DJ. Structure of the guide-strand-containing argonaute silencing complex. Nature. 456: 209-13. PMID 18754009 DOI: 10.1038/Nature07315  1
2008 Connolly E, Melegari M, Landgraf P, Tchaikovskaya T, Tennant BC, Slagle BL, Rogler LE, Zavolan M, Tuschl T, Rogler CE. Elevated expression of the miR-17-92 polycistron and miR-21 in hepadnavirus-associated hepatocellular carcinoma contributes to the malignant phenotype. The American Journal of Pathology. 173: 856-64. PMID 18688024 DOI: 10.2353/Ajpath.2008.080096  1
2008 Nie K, Gomez M, Landgraf P, Garcia JF, Liu Y, Tan LH, Chadburn A, Tuschl T, Knowles DM, Tam W. MicroRNA-mediated down-regulation of PRDM1/Blimp-1 in Hodgkin/Reed-Sternberg cells: a potential pathogenetic lesion in Hodgkin lymphomas. The American Journal of Pathology. 173: 242-52. PMID 18583325 DOI: 10.2353/Ajpath.2008.080009  1
2008 Teng G, Hakimpour P, Landgraf P, Rice A, Tuschl T, Casellas R, Papavasiliou FN. MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase. Immunity. 28: 621-9. PMID 18450484 DOI: 10.1016/J.Immuni.2008.03.015  1
2008 Farazi TA, Juranek SA, Tuschl T. The growing catalog of small RNAs and their association with distinct Argonaute/Piwi family members. Development (Cambridge, England). 135: 1201-14. PMID 18287206 DOI: 10.1242/Dev.005629  1
2008 Hafner M, Landgraf P, Ludwig J, Rice A, Ojo T, Lin C, Holoch D, Lim C, Tuschl T. Identification of microRNAs and other small regulatory RNAs using cDNA library sequencing. Methods (San Diego, Calif.). 44: 3-12. PMID 18158127 DOI: 10.1016/J.Ymeth.2007.09.009  1
2008 Chen PY, Weinmann L, Gaidatzis D, Pei Y, Zavolan M, Tuschl T, Meister G. Strand-specific 5'-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity. Rna (New York, N.Y.). 14: 263-74. PMID 18094121 DOI: 10.1261/Rna.789808  1
2007 Klenov MS, Lavrov SA, Stolyarenko AD, Ryazansky SS, Aravin AA, Tuschl T, Gvozdev VA. Repeat-associated siRNAs cause chromatin silencing of retrotransposons in the Drosophila melanogaster germline. Nucleic Acids Research. 35: 5430-8. PMID 17702759 DOI: 10.1093/Nar/Gkm576  1
2007 Ye JD, Barth CD, Anjaneyulu PS, Tuschl T, Piccirilli JA. Reactions of phosphate and phosphorothiolate diesters with nucleophiles: comparison of transition state structures. Organic & Biomolecular Chemistry. 5: 2491-7. PMID 17637971 DOI: 10.1039/B707205H  1
2007 Randall G, Panis M, Cooper JD, Tellinghuisen TL, Sukhodolets KE, Pfeffer S, Landthaler M, Landgraf P, Kan S, Lindenbach BD, Chien M, Weir DB, Russo JJ, Ju J, Brownstein MJ, ... ... Tuschl T, et al. Cellular cofactors affecting hepatitis C virus infection and replication. Proceedings of the National Academy of Sciences of the United States of America. 104: 12884-9. PMID 17616579 DOI: 10.1073/Pnas.0704894104  1
2007 Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, ... ... Tuschl T, et al. A mammalian microRNA expression atlas based on small RNA library sequencing. Cell. 129: 1401-14. PMID 17604727 DOI: 10.1016/J.Cell.2007.04.040  1
2007 Krützfeldt J, Kuwajima S, Braich R, Rajeev KG, Pena J, Tuschl T, Manoharan M, Stoffel M. Specificity, duplex degradation and subcellular localization of antagomirs. Nucleic Acids Research. 35: 2885-92. PMID 17439965 DOI: 10.1093/Nar/Gkm024  1
2007 Fulci V, Chiaretti S, Goldoni M, Azzalin G, Carucci N, Tavolaro S, Castellano L, Magrelli A, Citarella F, Messina M, Maggio R, Peragine N, Santangelo S, Mauro FR, Landgraf P, ... Tuschl T, et al. Quantitative technologies establish a novel microRNA profile of chronic lymphocytic leukemia. Blood. 109: 4944-51. PMID 17327404 DOI: 10.1182/Blood-2006-12-062398  1
2007 Tuschl T, Landgraf P, Ludwig J, Landthaler M, Sander C, Zavolan M. Mechanisms of small RNA mediated mammalian gene silencing The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A149-C  0.76
2006 Patel DJ, Ma JB, Yuan YR, Ye K, Pei Y, Kuryavyi V, Malinina L, Meister G, Tuschl T. Structural biology of RNA silencing and its functional implications. Cold Spring Harbor Symposia On Quantitative Biology. 71: 81-93. PMID 17381284 DOI: 10.1101/Sqb.2006.71.053  1
2006 Zhang X, Yuan YR, Pei Y, Lin SS, Tuschl T, Patel DJ, Chua NH. Cucumber mosaic virus-encoded 2b suppressor inhibits Arabidopsis Argonaute1 cleavage activity to counter plant defense. Genes & Development. 20: 3255-68. PMID 17158744 DOI: 10.1101/Gad.1495506  1
2006 Hossbach M, Gruber J, Osborn M, Weber K, Tuschl T. Gene silencing with siRNA duplexes composed of target-mRNA-complementary and partially palindromic or partially complementary single-stranded siRNAs. Rna Biology. 3: 82-9. PMID 17114944 DOI: 10.4161/Rna.3.2.3110  1
2006 Yuan YR, Pei Y, Chen HY, Tuschl T, Patel DJ. A potential protein-RNA recognition event along the RISC-loading pathway from the structure of A. aeolicus Argonaute with externally bound siRNA. Structure (London, England : 1993). 14: 1557-65. PMID 17027504 DOI: 10.1016/J.Str.2006.08.009  1
2006 Pei Y, Tuschl T. On the art of identifying effective and specific siRNAs. Nature Methods. 3: 670-6. PMID 16929310 DOI: 10.1038/Nmeth911  1
2006 Aravin A, Gaidatzis D, Pfeffer S, Lagos-Quintana M, Landgraf P, Iovino N, Morris P, Brownstein MJ, Kuramochi-Miyagawa S, Nakano T, Chien M, Russo JJ, Ju J, Sheridan R, Sander C, ... ... Tuschl T, et al. A novel class of small RNAs bind to MILI protein in mouse testes. Nature. 442: 203-7. PMID 16751777 DOI: 10.1038/Nature04916  1
2006 Tuschl T, Rossi J. Preface and overview Annals of the New York Academy of Sciences. 1082: xi-xiii. DOI: 10.1196/Annals.1348.067  1
2006 Borkhardt A, Fuchs U, Tuschl T. MicroRNA in chronic lymphocytic leukemia [1] New England Journal of Medicine. 354: 524. DOI: 10.1056/NEJMc053266  1
2005 Pfeffer S, Lagos-Quintana M, Tuschl T. Cloning of small RNA molecules. Current Protocols in Molecular Biology / Edited by Frederick M. Ausubel ... [Et Al.]. Unit 26.4. PMID 18265364 DOI: 10.1002/0471142727.Mb2604S72  1
2005 Gruber J, Manninga H, Tuschl T, Osborn M, Weber K. Specific RNAi mediated gene knockdown in zebrafish cell lines. Rna Biology. 2: 101-5. PMID 17114924 DOI: 10.4161/Rna.2.3.2060  1
2005 Meister G, Landthaler M, Peters L, Chen PY, Urlaub H, Lührmann R, Tuschl T. Identification of novel argonaute-associated proteins. Current Biology : Cb. 15: 2149-55. PMID 16289642 DOI: 10.1016/J.Cub.2005.10.048  1
2005 Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M. Identification of clustered microRNAs using an ab initio prediction method. Bmc Bioinformatics. 6: 267. PMID 16274478 DOI: 10.1186/1471-2105-6-267  1
2005 Krützfeldt J, Rajewsky N, Braich R, Rajeev KG, Tuschl T, Manoharan M, Stoffel M. Silencing of microRNAs in vivo with 'antagomirs' Nature. 438: 685-689. PMID 16258535 DOI: 10.1038/Nature04303  1
2005 Aravin A, Tuschl T. Identification and characterization of small RNAs involved in RNA silencing Febs Letters. 579: 5830-5840. PMID 16153643 DOI: 10.1016/J.Febslet.2005.08.009  1
2005 Yuan YR, Pei Y, Ma JB, Kuryavyi V, Zhadina M, Meister G, Chen HY, Dauter Z, Tuschl T, Patel DJ. Crystal structure of A. aeolicus argonaute, a site-specific DNA-guided endoribonuclease, provides insights into RISC-mediated mRNA cleavage. Molecular Cell. 19: 405-19. PMID 16061186 DOI: 10.1016/J.Molcel.2005.07.011  1
2005 Leaman D, Chen PY, Fak J, Yalcin A, Pearce M, Unnerstall U, Marks DS, Sander C, Tuschl T, Gaul U. Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development. Cell. 121: 1097-108. PMID 15989958 DOI: 10.1016/J.Cell.2005.04.016  1
2005 Chen PY, Manninga H, Slanchev K, Chien M, Russo JJ, Ju J, Sheridan R, John B, Marks DS, Gaidatzis D, Sander C, Zavolan M, Tuschl T. The developmental miRNA profiles of zebrafish as determined by small RNA cloning. Genes & Development. 19: 1288-93. PMID 15937218 DOI: 10.1101/Gad.1310605  1
2005 Altuvia Y, Landgraf P, Lithwick G, Elefant N, Pfeffer S, Aravin A, Brownstein MJ, Tuschl T, Margalit H. Clustering and conservation patterns of human microRNAs. Nucleic Acids Research. 33: 2697-706. PMID 15891114 DOI: 10.1093/Nar/Gki567  1
2005 Ma JB, Yuan YR, Meister G, Pei Y, Tuschl T, Patel DJ. Structural basis for 5'-end-specific recognition of guide RNA by the A. fulgidus Piwi protein. Nature. 434: 666-70. PMID 15800629 DOI: 10.1038/Nature03514  1
2005 Pfeffer S, Sewer A, Lagos-Quintana M, Sheridan R, Sander C, Grässer FA, van Dyk LF, Ho CK, Shuman S, Chien M, Russo JJ, Ju J, Randall G, Lindenbach BD, Rice CM, ... ... Tuschl T, et al. Identification of microRNAs of the herpesvirus family. Nature Methods. 2: 269-76. PMID 15782219 DOI: 10.1038/Nmeth746  1
2005 Paludan C, Schmid D, Landthaler M, Vockerodt M, Kube D, Tuschl T, Münz C. Endogenous MHC class II processing of a viral nuclear antigen after autophagy Science. 307: 593-596. PMID 15591165 DOI: 10.1126/Science.1104904  1
2005 Landgraf P, Rice A, Iovino N, Fulci V, Sheridan R, Fuchs U, Schmid I, Sander C, Chen M, Russo JJ, Ju J, Tam W, Macino G, Zavolan M, Borkhardt A, ... Tuschl T, et al. miRNA Profiling of Pediatric ALL and Non-Hodgkin Lymphomas. Blood. 106: 2719-2719. DOI: 10.1182/Blood.V106.11.2719.2719  0.36
2004 Landthaler M, Yalcin A, Tuschl T. The human DiGeorge syndrome critical region gene 8 and Its D. melanogaster homolog are required for miRNA biogenesis. Current Biology : Cb. 14: 2162-7. PMID 15589161 DOI: 10.1016/J.Cub.2004.11.001  1
2004 Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M. A pancreatic islet-specific microRNA regulates insulin secretion. Nature. 432: 226-30. PMID 15538371 DOI: 10.1038/Nature03076  1
2004 John B, Enright AJ, Aravin A, Tuschl T, Sander C, Marks DS. Human MicroRNA targets. Plos Biology. 2: e363. PMID 15502875 DOI: 10.1371/Journal.Pbio.0020363  1
2004 Meister G, Tuschl T. Mechanisms of gene silencing by double-stranded RNA. Nature. 431: 343-9. PMID 15372041 DOI: 10.1038/Nature02873  1
2004 Gruber J, Boese G, Tuschl T, Osborn M, Weber K. RNA interference by osmotic lysis of pinosomes: liposome-independent transfection of siRNAs into mammalian cells. Biotechniques. 37: 96-102. PMID 15283206 DOI: 10.2144/04371Rr01  1
2004 Meister G, Landthaler M, Patkaniowska A, Dorsett Y, Teng G, Tuschl T. Human Argonaute2 mediates RNA cleavage targeted by miRNAs and siRNAs. Molecular Cell. 15: 185-97. PMID 15260970 DOI: 10.1016/J.Molcel.2004.07.007  1
2004 Yuan B, Latek R, Hossbach M, Tuschl T, Lewitter F. siRNA selection server: An automated siRNA oligonucleotide predicition server Nucleic Acids Research. 32: W130-W134. PMID 15215365 DOI: 10.1093/Nar/Gkh366  1
2004 Will CL, Schneider C, Hossbach M, Urlaub H, Rauhut R, Elbashir S, Tuschl T, Lührmann R. The human 18S U11/U12 snRNP contains a set of novel proteins not found in the U2-dependent spliceosome Rna. 10: 929-941. PMID 15146077 DOI: 10.1261/Rna.7320604  1
2004 Pfeffer S, Zavolan M, Grässer FA, Chien M, Russo JJ, Ju J, John B, Enright AJ, Marks D, Sander C, Tuschl T. Identification of virus-encoded microRNAs. Science (New York, N.Y.). 304: 734-6. PMID 15118162 DOI: 10.1126/Science.1096781  1
2004 Martinez J, Tuschl T. RISC is a 5′ phosphomonoester-producing RNA endonuclease Genes and Development. 18: 975-980. PMID 15105377 DOI: 10.1101/Gad.1187904  1
2004 Dorsett Y, Tuschl T. siRNAs: Applications in functional genomics and potential as therapeutics Nature Reviews Drug Discovery. 3: 318-329. PMID 15060527 DOI: 10.1038/Nrd1345  1
2004 Meister G, Landthaler M, Dorsett Y, Tuschl T. Sequence-specific inhibition of microRNA-and siRNA-induced RNA silencing Rna. 10: 544-550. PMID 14970398 DOI: 10.1261/Rna.5235104  1
2003 Enright AJ, John B, Gaul U, Tuschl T, Sander C, Marks DS. MicroRNA targets in Drosophila. Genome Biology. 5: R1. PMID 14709173 DOI: 10.1186/Gb-2003-5-1-R1  1
2003 Martinez J, Patkaniowska A, Elbashir SM, Harborth J, Hossbach M, Urlaub H, Meyer J, Weber K, Vandenburgh K, Manninga H, Scaringe SA, Luehrmann R, Tuschl T. Analysis of mammalian gene function using small interfering RNAs Nucleic Acids Research. Supplement (2001). 333. PMID 14510516  1
2003 Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B, Gaasterland T, Meyer J, Tuschl T. The small RNA profile during Drosophila melanogaster development. Developmental Cell. 5: 337-50. PMID 12919683 DOI: 10.1016/S1534-5807(03)00228-4  1
2003 Harborth J, Elbashir SM, Vandenburgh K, Manninga H, Scaringe SA, Weber K, Tuschl T. Sequence, chemical, and structural variation of small interfering RNAs and short hairpin RNAs and the effect on mammalian gene silencing Antisense and Nucleic Acid Drug Development. 13: 83-105. PMID 12804036 DOI: 10.1089/108729003321629638  1
2003 Ambros V, Bartel B, Bartel DP, Burge CB, Carrington JC, Chen X, Dreyfuss G, Eddy SR, Griffiths-Jones S, Marshall M, Matzke M, Ruvkun G, Tuschl T. A uniform system for microRNA annotation. Rna (New York, N.Y.). 9: 277-9. PMID 12592000 DOI: 10.1261/Rna.2183803  1
2003 Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T. New microRNAs from mouse and human Rna. 9: 175-179. PMID 12554859 DOI: 10.1261/Rna.2146903  1
2003 Tuschl T. Functional genomics: RNA sets the standard Nature. 421: 220-221. PMID 12529623 DOI: 10.1038/421220A  1
2002 Tuschl T, Borkhardt A. Small interfering RNAs: a revolutionary tool for the analysis of gene function and gene therapy Mol Interv. 2: 158-167. PMID 14993376 DOI: 10.1124/Mi.2.3.158  1
2002 Martinez J, Patkaniowska A, Urlaub H, Lührmann R, Tuschl T. Single-stranded antisense siRNAs guide target RNA cleavage in RNAi Cell. 110: 563-574. PMID 12230974 DOI: 10.1016/S0092-8674(02)00908-X  1
2002 Elbashir SM, Harborth J, Weber K, Tuschl T. Analysis of gene function in somatic mammalian cells using small interfering RNAs Methods. 26: 199-213. PMID 12054897 DOI: 10.1016/S1046-2023(02)00023-3  1
2002 Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T. Identification of tissue-specific microRNAs from mouse. Current Biology : Cb. 12: 735-9. PMID 12007417 DOI: 10.1016/S0960-9822(02)00809-6  1
2002 Tuschl T. Expanding small RNA interference Nature Biotechnology. 20: 446-448. PMID 11981553 DOI: 10.1038/Nbt0502-446  1
2001 Tuschl T. RNA interference and small interfering RNAs Chembiochem. 2: 239-245. PMID 11828450 DOI: 10.1002/1439-7633(20010401)2:4<239::Aid-Cbic239>3.0.Co;2-R  1
2001 Harborth J, Elbashir SM, Bechert K, Tuschl T, Weber K. Identification of essential genes in cultured mammalian cells using small interfering RNAs Journal of Cell Science. 114: 4557-4565. PMID 11792820  1
2001 Elbashir SM, Martinez J, Patkaniowska A, Lendeckel W, Tuschl T. Functional anatomy of siRNAs for mediating efficient RNAi in Drosophila melanogaster embryo lysate Embo Journal. 20: 6877-6888. PMID 11726523 DOI: 10.1093/Emboj/20.23.6877  1
2001 Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T. Identification of novel genes coding for small expressed RNAs Science. 294: 853-858. PMID 11679670 DOI: 10.1126/Science.1064921  1
2001 Hutvágner G, McLachlan J, Pasquinelli AE, Bálint E, Tuschl T, Zamore PD. A cellular function for the RNA-interference enzyme Dicer in the maturation of the let-7 small temporal RNA. Science (New York, N.Y.). 293: 834-8. PMID 11452083 DOI: 10.1126/Science.1062961  1
2001 Elbashir SM, Harborth J, Lendeckel W, Yalcin A, Weber K, Tuschl T. Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells Nature. 411: 494-498. PMID 11373684 DOI: 10.1038/35078107  1
2001 Tuschl T, Sharp PA, Bartel DP. A ribozyme selected from variants of U6 snRNA promotes 2',5'-branch formation. Rna (New York, N.Y.). 7: 29-43. PMID 11214178 DOI: 10.1017/S1355838201001510  1
2001 Elbashir SM, Lendeckel W, Tuschl T. RNA interference is mediated by 21- and 22-nucleotide RNAs Genes and Development. 15: 188-200. PMID 11157775 DOI: 10.1101/Gad.862301  1
2000 Zamore PD, Tuschl T, Sharp PA, Bartel DP. RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell. 101: 25-33. PMID 10778853 DOI: 10.1016/S0092-8674(00)80620-0  1
1999 Tuschl T, Zamore PD, Lehmann R, Bartel DP, Sharp PA. Targeted mRNA degradation by double-stranded RNA in vitro. Genes & Development. 13: 3191-7. PMID 10617568 DOI: 10.1101/Gad.13.24.3191  1
1999 Burge CB, Tuschl T, Sharp PA. 20 Splicing of Precursors to mRNAs by the Spliceosomes Cold Spring Harbor Monograph Archive. 37: 525-560. DOI: 10.1101/087969589.37.525  0.96
1998 Tuschl T, Sharp PA, Bartel DP. Selection in vitro of novel ribozymes from a partially randomized U2 and U6 snRNA library. The Embo Journal. 17: 2637-50. PMID 9564046 DOI: 10.1093/Emboj/17.9.2637  1
1996 Menger M, Tuschl T, Eckstein F, Porschke D. Mg(2+)-dependent conformational changes in the hammerhead ribozyme. Biochemistry. 35: 14710-6. PMID 8942631 DOI: 10.1021/Bi960440W  1
1995 Tuschl T, Thomson JB, Eckstein F. RNA cleavage by small catalytic RNAs. Current Opinion in Structural Biology. 5: 296-302. PMID 7583627 DOI: 10.1016/0959-440X(95)80090-5  1
1995 Sigurdsson ST, Tuschl T, Eckstein F. Probing RNA tertiary structure: interhelical crosslinking of the hammerhead ribozyme. Rna (New York, N.Y.). 1: 575-83. PMID 7489517  1
1994 Aurup H, Tuschl T, Benseler F, Ludwig J, Eckstein F. Oligonucleotide duplexes containing 2'-amino-2'-deoxycytidines: thermal stability and chemical reactivity. Nucleic Acids Research. 22: 20-4. PMID 8127651 DOI: 10.1093/Nar/22.1.20  1
1994 Tuschl T, Gohlke C, Jovin TM, Westhof E, Eckstein F. A three-dimensional model for the hammerhead ribozyme based on fluorescence measurements. Science (New York, N.Y.). 266: 785-9. PMID 7973630 DOI: 10.1126/Science.7973630  1
1994 Ng MM, Benseler F, Tuschl T, Eckstein F. Isoguanosine substitution of conserved adenosines in the hammerhead ribozyme. Biochemistry. 33: 12119-26. PMID 7918433 DOI: 10.1021/Bi00206A015  1
1994 Aurup H, Tuschl T, Benseler F, Ludwig J, Eckstein F. Oligonucleotide duplexes containing 2′-amino-2′deoxycytidines: Thermal stability and chemical reactivity Nucleic Acids Research. 22: 701. DOI: 10.1093/nar/22.4.701  1
1993 Tuschl T, Eckstein F. Hammerhead ribozymes: importance of stem-loop II for activity. Proceedings of the National Academy of Sciences of the United States of America. 90: 6991-4. PMID 8346207 DOI: 10.1073/Pnas.90.15.6991  1
1993 Eckstein F, Aurup H, Benseler F, Heidenreich O, Marschall P, Ng M, Thomson J, Tuschl T. Design of hammerhead ribozymes for the inhibition of gene expression ex vivo by exogenous application. Nucleic Acids Symposium Series. 115. PMID 8247729  1
1993 Tuschl T, Ng MM, Pieken W, Benseler F, Eckstein F. Importance of exocyclic base functional groups of central core guanosines for hammerhead ribozyme activity. Biochemistry. 32: 11658-68. PMID 8218233 DOI: 10.1021/Bi00094A023  1
1993 Thomson JB, Tuschl T, Eckstein F. Activity of hammerhead ribozymes containing non-nucleotidic linkers. Nucleic Acids Research. 21: 5600-3. PMID 7506829 DOI: 10.1093/Nar/21.24.5600  1
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