Year |
Citation |
Score |
2018 |
Mulcahy MJ, Paulo JA, Hawrot E. Proteomic Investigation of Murine Neuronal α7-Nicotinic Acetylcholine Receptor Interacting Proteins. Journal of Proteome Research. PMID 30285449 DOI: 10.1021/Acs.Jproteome.8B00618 |
0.578 |
|
2015 |
Mulcahy MJ, Blattman SB, Barrantes FJ, Lukas RJ, Hawrot E. Resistance to Inhibitors of Cholinesterase 3 (Ric-3) Expression Promotes Selective Protein Associations with the Human α7-Nicotinic Acetylcholine Receptor Interactome. Plos One. 10: e0134409. PMID 26258666 DOI: 10.1371/Journal.Pone.0134409 |
0.359 |
|
2013 |
Hawrot E. Connecting the dots between G proteins, G protein coupled receptors, and neuronal nicotinic acetylcholine receptors (Comment on DOI 10.1002/bies.201300082). Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 1022. PMID 24242098 DOI: 10.1002/Bies.201300148 |
0.59 |
|
2013 |
Mulcahy MJ, Lukas RJ, Barrantes FJ, Hawrot E. Proteomic investigation of human α7-nicotinic acetylcholine receptor signaling mechanisms Biochemical Pharmacology. 86: 1227-1228. DOI: 10.1016/J.Bcp.2013.08.037 |
0.417 |
|
2010 |
Peng C, Chen W, Sanders T, Chew G, Liu J, Hawrot E, Chi C. Chemical synthesis and characterization of two α4/7-conotoxins. Acta Biochimica Et Biophysica Sinica. 42: 745-53. PMID 20801929 DOI: 10.1093/Abbs/Gmq074 |
0.46 |
|
2010 |
Peng C, Ye M, Wang Y, Shao X, Yuan D, Liu J, Hawrot E, Wang C, Chi C. A new subfamily of conotoxins belonging to the A-superfamily. Peptides. 31: 2009-16. PMID 20691232 DOI: 10.1016/J.Peptides.2010.07.011 |
0.348 |
|
2010 |
Moise L, Liu J, Pryazhnikov E, Khiroug L, Jeromin A, Hawrot E. K(V)4.2 channels tagged in the S1-S2 loop for alpha-bungarotoxin binding provide a new tool for studies of channel expression and localization. Channels (Austin, Tex.). 4: 115-23. PMID 20139708 DOI: 10.4161/Chan.4.2.10878 |
0.629 |
|
2009 |
Caffery PM, Krishnaswamy A, Sanders T, Liu J, Hartlaub H, Klysik J, Cooper E, Hawrot E. Engineering neuronal nicotinic acetylcholine receptors with functional sensitivity to alpha-bungarotoxin: a novel alpha3-knock-in mouse. The European Journal of Neuroscience. 30: 2064-76. PMID 20128845 DOI: 10.1111/J.1460-9568.2009.07016.X |
0.794 |
|
2009 |
Peng C, Chen W, Han Y, Sanders T, Chew G, Liu J, Hawrot E, Chi C, Wang C. Characterization of a novel alpha4/4-conotoxin, Qc1.2, from vermivorous Conus quercinus. Acta Biochimica Et Biophysica Sinica. 41: 858-64. PMID 19779652 DOI: 10.1093/Abbs/Gmp077 |
0.581 |
|
2009 |
Paulo JA, Brucker WJ, Hawrot E. Proteomic analysis of an alpha7 nicotinic acetylcholine receptor interactome. Journal of Proteome Research. 8: 1849-58. PMID 19714875 DOI: 10.1021/Pr800731Z |
0.715 |
|
2009 |
Paulo JA, Hawrot E. Effect of homologous serotonin receptor loop substitutions on the heterologous expression in Pichia of a chimeric acetylcholine-binding protein with alpha-bungarotoxin-binding activity. Protein Expression and Purification. 67: 76-81. PMID 19427904 DOI: 10.1016/J.Pep.2009.05.001 |
0.534 |
|
2009 |
Paulo JA, Hawrot E. A radioisotope label-free alpha-bungarotoxin-binding assay using BIAcore sensor chip technology for real-time analysis. Analytical Biochemistry. 389: 86-8. PMID 19289092 DOI: 10.1016/J.Ab.2009.03.011 |
0.682 |
|
2008 |
Peng C, Han Y, Sanders T, Chew G, Liu J, Hawrot E, Chi C, Wang C. alpha4/7-conotoxin Lp1.1 is a novel antagonist of neuronal nicotinic acetylcholine receptors. Peptides. 29: 1700-7. PMID 18588930 DOI: 10.1016/J.Peptides.2008.05.028 |
0.564 |
|
2007 |
Liu L, Chew G, Hawrot E, Chi C, Wang C. Two potent alpha3/5 conotoxins from piscivorous Conus achatinus. Acta Biochimica Et Biophysica Sinica. 39: 438-44. PMID 17558449 DOI: 10.1111/J.1745-7270.2007.00301.X |
0.605 |
|
2004 |
Sanders T, Hawrot E. A novel pharmatope tag inserted into the beta4 subunit confers allosteric modulation to neuronal nicotinic receptors. The Journal of Biological Chemistry. 279: 51460-5. PMID 15448163 DOI: 10.1074/Jbc.M409533200 |
0.668 |
|
2002 |
Zeng H, Hawrot E. NMR-based binding screen and structural analysis of the complex formed between alpha-cobratoxin and an 18-mer cognate peptide derived from the alpha 1 subunit of the nicotinic acetylcholine receptor from Torpedo californica. The Journal of Biological Chemistry. 277: 37439-45. PMID 12133834 DOI: 10.1074/Jbc.M205483200 |
0.738 |
|
2002 |
Moise L, Piserchio A, Basus VJ, Hawrot E. NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 277: 12406-17. PMID 11790782 DOI: 10.1074/Jbc.M110320200 |
0.782 |
|
2002 |
Moise L, Zeng H, Caffery P, Rogowski RS, Hawrot E. Structure and function of α-Bungarotoxin Journal of Toxicology - Toxin Reviews. 21: 293-317. DOI: 10.1081/Txr-120014407 |
0.729 |
|
2001 |
Zeng H, Moise L, Grant MA, Hawrot E. The solution structure of the complex formed between alpha-bungarotoxin and an 18-mer cognate peptide derived from the alpha 1 subunit of the nicotinic acetylcholine receptor from Torpedo californica. The Journal of Biological Chemistry. 276: 22930-40. PMID 11312275 DOI: 10.1074/Jbc.M102300200 |
0.798 |
|
2000 |
Blein S, Hawrot E, Barlow P. The metabotropic GABA receptor: Molecular insights and their functional consequences Cellular and Molecular Life Sciences. 57: 635-650. PMID 11130463 DOI: 10.1007/Pl00000725 |
0.374 |
|
2000 |
Spura A, Riel RU, Freedman ND, Agrawal S, Seto C, Hawrot E. Biotinylation of substituted cysteines in the nicotinic acetylcholine receptor reveals distinct binding modes for α-bungarotoxin and erabutoxin a Journal of Biological Chemistry. 275: 22452-22460. PMID 10791957 DOI: 10.1074/Jbc.M001283200 |
0.803 |
|
2000 |
Levandoski MM, Caffery PM, Rogowski RS, Lin Y, Shi QL, Hawrot E. Recombinant expression of alpha-bungarotoxin in Pichia pastoris facilitates identification of mutant toxins engineered to recognize neuronal nicotinic acetylcholine receptors. Journal of Neurochemistry. 74: 1279-89. PMID 10693962 DOI: 10.1046/J.1471-4159.2000.741279.X |
0.798 |
|
1999 |
Levandoski MM, Lin Y, Moise L, McLaughlin JT, Cooper E, Hawrot E. Chimeric analysis of a neuronal nicotinic acetylcholine receptor reveals amino acids conferring sensitivity to alpha-bungarotoxin. The Journal of Biological Chemistry. 274: 26113-9. PMID 10473561 DOI: 10.1074/jbc.274.37.26113 |
0.743 |
|
1999 |
Grant MA, Gentile LN, Shi QL, Pellegrini M, Hawrot E. Expression and spectroscopic analysis of soluble nicotinic acetylcholine receptor fragments derived from the extracellular domain of the alpha-subunit. Biochemistry. 38: 10730-42. PMID 10451368 DOI: 10.1021/Bi983007Q |
0.623 |
|
1999 |
Rosenthal JA, Levandoski MM, Chang B, Potts JF, Shi QL, Hawrot E. The functional role of positively charged amino acid side chains in α- bungarotoxin revealed by site-directed mutagenesis of a His-tagged recombinant α-bungarotoxin Biochemistry. 38: 7847-7855. PMID 10387025 DOI: 10.1021/Bi990045G |
0.503 |
|
1999 |
Spura A, Russin TS, Freedman ND, Grant M, McLaughlin JT, Hawrot E. Probing the agonist domain of the nicotinic acetylcholine receptor by cysteine scanning mutagenesis reveals residues in proximity to the alpha-bungarotoxin binding site. Biochemistry. 38: 4912-21. PMID 10213592 DOI: 10.1021/Bi982656Z |
0.802 |
|
1998 |
Hawrot E, Xiao Y, Shi QL, Norman D, Kirkitadze M, Barlow PN. Demonstration of a tandem pair of complement protein modules in GABA(B) receptor 1a. Febs Letters. 432: 103-8. PMID 9720905 DOI: 10.1016/S0014-5793(98)00794-7 |
0.339 |
|
1998 |
Blein S, Barlow PN, Hawrot E. Structural study of the N-terminal membrane distal region of GABAB receptor GABABR1a Molecular Immunology. 35: 384. DOI: 10.1016/S0161-5890(98)90746-5 |
0.346 |
|
1995 |
Gentile LN, Basus VJ, Shi QL, Hawrot E. Preliminary two-dimensional [1H]NMR characterization of the complex formed between an 18-amino acid peptide fragment of the α-subunit of the nicotinic acetylcholine receptor and α-bungarotoxin Annals of the New York Academy of Sciences. 757: 222-237. PMID 7611677 DOI: 10.1111/J.1749-6632.1995.Tb17479.X |
0.429 |
|
1995 |
Gentile LN, Hawrot E. Methods for increasing the expression level of a soluble fusion protein encoding a 62 amino acid fragment of the α-subunit of the nicotinic acetylcholine receptor Annals of the New York Academy of Sciences. 757: 117-119. PMID 7611668 DOI: 10.1111/J.1749-6632.1995.Tb17468.X |
0.454 |
|
1995 |
McLaughlin JT, Hawrot E, Yellen G. Covalent modification of engineered cysteines in the nicotinic acetylcholine receptor agonist-binding domain inhibits receptor activation. The Biochemical Journal. 310: 765-9. PMID 7575408 DOI: 10.1042/Bj3100765 |
0.62 |
|
1994 |
Rosenthal JA, Hsu SH, Schneider D, Gentile LN, Messier NJ, Vaslet CA, Hawrot E. Functional expression and site-directed mutagenesis of a synthetic gene for alpha-bungarotoxin. The Journal of Biological Chemistry. 269: 11178-85. PMID 8157645 |
0.523 |
|
1993 |
Basus VJ, Song G, Hawrot E. NMR solution structure of an α-bungarotoxin/nicotinic receptor peptide complex Biochemistry. 32: 12290-12298. PMID 8241115 DOI: 10.1021/Bi00097A004 |
0.522 |
|
1993 |
Shi QL, Hawrot E. Exploration of the possible role in agonist and antagonist binding activities of the disulfide bond between cys-192 and cys-193 in the α-subunit of the torpedo californiea acetylcholine receptor Protein Engineering, Design and Selection. 6: 82. DOI: 10.1093/protein/6.Supplement.82-b |
0.356 |
|
1992 |
Schlyer BD, Maki AH, Hawrot E. alpha-Bungarotoxin binding to two acetylcholine receptor alpha-peptides and their methylmercury-modified analogs: intrinsic phosphorescence and optically detected magnetic resonance studies. Febs Letters. 297: 87-90. PMID 1551443 DOI: 10.1016/0014-5793(92)80333-C |
0.489 |
|
1992 |
Tringali AE, Pearce SFA, Hawrot E, Brenner HC. Phosphorescence and ODMR study of the binding interactions of acetylcholine receptor α-subunit peptides with α-cobratoxin Febs Letters. 308: 225-228. PMID 1499734 DOI: 10.1016/0014-5793(92)81279-U |
0.591 |
|
1991 |
Tomaselli GF, McLaughlin JT, Jurman ME, Hawrot E, Yellen G. Mutations affecting agonist sensitivity of the nicotinic acetylcholine receptor. Biophysical Journal. 60: 721-7. PMID 1718469 DOI: 10.1016/S0006-3495(91)82102-6 |
0.493 |
|
1991 |
Horne WA, Hawrot E, Tsien RW. omega-Conotoxin GVIA receptors of Discopyge electric organ. Characterization of omega-conotoxin binding to the nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 266: 13719-25. PMID 1649828 |
0.504 |
|
1990 |
Song GQ, Armitage IM, Hawrot E. A binding site peptide fragment of the nicotinic acetylcholine receptor. Sequence-specific assignment of 1H-NMR resonances in the dodecamer alpha 185-196. Biochemical Pharmacology. 40: 63-5. PMID 2372313 DOI: 10.1016/0006-2952(90)90179-O |
0.507 |
|
1990 |
Preston-Hurlburt P, Wilson PT, Dowding AJ, Hawrot E. Monoclonal antibodies directed against a synthetic peptide corresponding to the α-bungarotoxin binding region of the acetylcholine receptor Bba - General Subjects. 1033: 324-328. PMID 2317509 DOI: 10.1016/0304-4165(90)90141-I |
0.427 |
|
1990 |
Pearce SF, Hawrot E. Intrinsic fluorescence of binding-site fragments of the nicotinic acetylcholine receptor: Perturbations produced upon binding α-bungarotoxin Biochemistry. 29: 10649-10659. PMID 2271674 DOI: 10.1021/Bi00499A011 |
0.418 |
|
1990 |
Pearce SFA, Preston-Hurlburt P, Hawrot E. The role of tyrosine at the ligand-binding site of the nicotinic acetylcholine receptor Proceedings of the Royal Society B: Biological Sciences. 241: 207-213. PMID 1979446 DOI: 10.1098/Rspb.1990.0087 |
0.497 |
|
1989 |
Chiles C, Hawrot E, Gore J, Byck R. Magnetic field modulation of receptor binding Magnetic Resonance in Medicine. 10: 241-245. PMID 2761382 DOI: 10.1002/Mrm.1910100208 |
0.325 |
|
1989 |
McLaughlin JT, Hawrot E. Structural characterization of alpha-bungarotoxin-binding proteins from Aplysia californica. Molecular Pharmacology. 35: 593-8. PMID 2542757 |
0.478 |
|
1988 |
Wilson PT, Hawrot E, Lentz TL. Distribution of α-bungarotoxin binding sites over residues 173-204 of the α subunit of the acetylcholine receptor Molecular Pharmacology. 34: 643-650. PMID 3193956 |
0.324 |
|
1988 |
Lentz TL, Hawrot E, Donnelly-Roberts D, Wilson PT. Synthetic peptides in the study of the interaction of rabies virus and the acetylcholine receptor Advances in Biochemical Psychopharmacology. 44: 57-71. PMID 3041753 |
0.361 |
|
1988 |
Hawrot E, Colson KL, Lentz TL, Wilson PT. Chapter 9 Synthetic Peptides in the Study of the Nicotinic Acetylcholine Receptor Current Topics in Membranes and Transport. 33: 165-195. DOI: 10.1016/S0070-2161(08)60899-0 |
0.39 |
|
1987 |
Lentz TL, Hawrot E, Wilson PT. Synthetic peptides corresponding to sequences of snake venom neurotoxins and rabies virus glycoprotein bind to the nicotinic acetylcholine receptor Proteins: Structure, Function and Genetics. 2: 298-307. PMID 3448605 DOI: 10.1002/Prot.340020406 |
0.442 |
|
1987 |
Deutch AY, Holliday J, Roth RH, Chun LL, Hawrot E. Immunohistochemical localization of a neuronal nicotinic acetylcholine receptor in mammalian brain. Proceedings of the National Academy of Sciences of the United States of America. 84: 8697-701. PMID 3317419 DOI: 10.1073/Pnas.84.23.8697 |
0.476 |
|
1987 |
Rosenberg MB, Breakefield XO, Hawrot E. Targeting of Liposomes to Cells Bearing Nerve Growth Factor Receptors Mediated by Biotinylated Nerve Growth Factor Journal of Neurochemistry. 48: 865-875. PMID 3027260 DOI: 10.1111/J.1471-4159.1987.Tb05597.X |
0.306 |
|
1987 |
Chase BA, Holliday J, Reese JH, Chun LL, Hawrot E. Monoclonal antibodies with defined specificities for Torpedo nicotinic acetylcholine receptor cross-react with Drosophila neural tissue. Neuroscience. 21: 959-76. PMID 2442658 DOI: 10.1016/0306-4522(87)90051-0 |
0.364 |
|
1986 |
Lentz TL, Benson RJ, Klimowicz D, Wilson PT, Hawrot E. Binding of rabies virus to purified Torpedo acetylcholine receptor. Brain Research. 387: 211-9. PMID 3828757 DOI: 10.1016/0169-328X(86)90027-6 |
0.424 |
|
1986 |
Hawrot E, Wilson PT, Gershoni JM, Reese JH, Lentz TL. α-Bungarotoxin binding to a high molecular weight component from lower vertebrate brain identified on dodecyl sulfate protein-blots Brain Research. 373: 227-234. PMID 3719308 DOI: 10.1016/0006-8993(86)90335-5 |
0.422 |
|
1986 |
Rosenberg MB, Hawrot E, Breakefield XO. Receptor Binding Activities of Biotinylated Derivatives of β‐Nerve Growth Factor Journal of Neurochemistry. 46: 641-648. PMID 3001230 DOI: 10.1111/J.1471-4159.1986.Tb13015.X |
0.367 |
|
1986 |
WILSON PT, LENTZ TL, HAWROT E. Mapping of the Alpha‐Bungarotoxin Binding Site on the Primary Amino Acid Sequence of the Torpedo Acetylcholine Receptor Annals of the New York Academy of Sciences. 463: 243-246. DOI: 10.1111/J.1749-6632.1986.Tb21559.X |
0.377 |
|
1985 |
Lentz TL, Chester J, Benson RJ, Hawrot E, Tignor GH, Smith AL. Rabies virus binding to cellular membranes measured by enzyme immunoassay. Muscle & Nerve. 8: 336-45. PMID 16758601 DOI: 10.1002/Mus.880080411 |
0.343 |
|
1985 |
Wilson PT, Lentz TL, Hawrot E. Determination of the primary amino acid sequence specifying the α-bungarotoxin binding site on the α subunit of the acetylcholine receptor from Torpedo californica Proceedings of the National Academy of Sciences of the United States of America. 82: 8790-8794. PMID 3866252 DOI: 10.1073/Pnas.82.24.8790 |
0.453 |
|
1984 |
Lentz TL, Wilson PT, Hawrot E, Speicher DW. Amino acid sequence similarity between rabies virus glycoprotein and snake venom curaremimetic neurotoxins Science. 226: 847-848. PMID 6494916 DOI: 10.1126/Science.6494916 |
0.412 |
|
1984 |
Wilson PT, Gershoni JM, Hawrot E, Lentz TL. Binding of α-bungarotoxin to proteolytic fragments of the α subunit of Torpedo acetylcholine receptor analyzed by protein transfer on positively charged membrane filters Proceedings of the National Academy of Sciences of the United States of America. 81: 2553-2557. PMID 6371817 DOI: 10.1073/Pnas.81.8.2553 |
0.463 |
|
1983 |
Gershoni JM, Hawrot E, Lentz TL. Binding of alpha-bungarotoxin to isolated alpha subunit of the acetylcholine receptor of Torpedo californica: quantitative analysis with protein blots Proceedings of the National Academy of Sciences of the United States of America. 80: 4973-4977. PMID 6576369 DOI: 10.1073/Pnas.80.16.4973 |
0.63 |
|
1982 |
Langley KE, Hawrot E, Kennedy EP. Membrane assembly: movement of phosphatidylserine between the cytoplasmic and outer membranes of Escherichia coli. Journal of Bacteriology. 152: 1033-41. PMID 6754694 |
0.477 |
|
1982 |
Gershoni JM, Palade GE, Hawrot E. Analysis of α-bungarotoxin binding to torpedo acetylcholine receptor by electrophoretic transfer techniques Journal of Cell Biology. 95: no. 21046. |
0.307 |
|
1979 |
Hawrot E, Patterson PH. Long-term culture of dissociated sympathetic neurons. Methods in Enzymology. 58: 574-84. PMID 423793 DOI: 10.1016/S0076-6879(79)58174-9 |
0.48 |
|
1979 |
Tyhach RJ, Hawrot E, Satre M, Kennedy EP. Increased synthesis of phosphatidylserine decarboxylase in a strain of Escherichia coli bearing a hybrid plasmid. Altered association of enzyme with the membrane. The Journal of Biological Chemistry. 254: 627-33. PMID 368058 |
0.489 |
|
1978 |
Hawrot E, Kennedy EP. Phospholipid composition and membrane function in phosphatidylserine decarboxylase mutants of Escherichia coli. The Journal of Biological Chemistry. 253: 8213-20. PMID 361737 |
0.48 |
|
1976 |
Hawrot E, Kennedy EP. Conditional lethal phosphatidylserine decarboxylase mutants of Escherichia coli. Mapping of the structural gene for phosphatidylserine decarboxylase. Molecular & General Genetics : Mgg. 148: 271-9. PMID 796663 DOI: 10.1007/Bf00332901 |
0.544 |
|
1975 |
Hawrot E, Kennedy EP. Biogenesis of membrane lipids: mutants of Escherichia coli with temperature-sensitive phosphatidylserine decarboxylase. Proceedings of the National Academy of Sciences of the United States of America. 72: 1112-6. PMID 1093166 DOI: 10.1073/Pnas.72.3.1112 |
0.542 |
|
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