Jerold Last - Publications

Affiliations: 
University of California, Davis, Davis, CA 
Area:
Toxicology, Biochemistry, Pharmacology

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Cagle L, Linderholm A, Franzi L, Hoehne S, Last J, Kenyon N, Illek B, Harper R. Role of Dual Oxidases in Ventilator-induced Lung Injury. American Journal of Respiratory Cell and Molecular Biology. PMID 33253594 DOI: 10.1165/rcmb.2020-0197OC  0.356
2018 Bratt JM, Chang KY, Rabowsky M, Franzi LM, Ott SP, Filosto S, Goldkorn T, Arif M, Last JA, Kenyon NJ, Zeki AA. Farnesyltransferase Inhibition Exacerbates Eosinophilic Inflammation and Airway Hyperreactivity in Mice with Experimental Asthma: The Complex Roles of Ras GTPase and Farnesylpyrophosphate in Type 2 Allergic Inflammation. Journal of Immunology (Baltimore, Md. : 1950). PMID 29703864 DOI: 10.4049/Jimmunol.1601317  0.732
2015 Zeki AA, Bratt JM, Chang KY, Franzi LM, Ott S, Silveria M, Fiehn O, Last JA, Kenyon NJ. Intratracheal instillation of pravastatin for the treatment of murine allergic asthma: a lung-targeted approach to deliver statins. Physiological Reports. 3. PMID 25969462 DOI: 10.14814/Phy2.12352  0.78
2013 Zeki AA, Oldham J, Wilson M, Fortenko O, Goyal V, Last M, Last A, Patel A, Last JA, Kenyon NJ. Statin use and asthma control in patients with severe asthma. Bmj Open. 3. PMID 23943778 DOI: 10.1136/bmjopen-2013-003314  0.347
2013 Williams KM, Franzi LM, Last JA. Cell-specific oxidative stress and cytotoxicity after wildfire coarse particulate matter instillation into mouse lung. Toxicology and Applied Pharmacology. 266: 48-55. PMID 23142465 DOI: 10.1016/J.Taap.2012.10.017  0.623
2011 Bratt JM, Zeki AA, Last JA, Kenyon NJ. Competitive metabolism of L-arginine: arginase as a therapeutic target in asthma. Journal of Biomedical Research. 25: 299-308. PMID 23554705 DOI: 10.1016/S1674-8301(11)60041-9  0.757
2011 Franzi LM, Bratt JM, Williams KM, Last JA. Why is particulate matter produced by wildfires toxic to lung macrophages? Toxicology and Applied Pharmacology. 257: 182-8. PMID 21945489 DOI: 10.1016/J.Taap.2011.09.003  0.744
2011 Filosto S, Castillo S, Danielson A, Franzi L, Khan E, Kenyon N, Last J, Pinkerton K, Tuder R, Goldkorn T. Neutral sphingomyelinase 2: a novel target in cigarette smoke-induced apoptosis and lung injury. American Journal of Respiratory Cell and Molecular Biology. 44: 350-60. PMID 20448054 DOI: 10.1165/Rcmb.2009-0422Oc  0.363
2010 Zeki AA, Bratt JM, Rabowsky M, Last JA, Kenyon NJ. Simvastatin inhibits goblet cell hyperplasia and lung arginase in a mouse model of allergic asthma: a novel treatment for airway remodeling? Translational Research : the Journal of Laboratory and Clinical Medicine. 156: 335-49. PMID 21078495 DOI: 10.1016/J.Trsl.2010.09.003  0.775
2010 Bratt JM, Williams K, Rabowsky MF, Last MS, Franzi LM, Last JA, Kenyon NJ. Nitric oxide synthase enzymes in the airways of mice exposed to ovalbumin: NOS2 expression is NOS3 dependent. Mediators of Inflammation. 2010. PMID 20953358 DOI: 10.1155/2010/321061  0.79
2010 Wegesser TC, Franzi LM, Mitloehner FM, Eiguren-Fernandez A, Last JA. Lung antioxidant and cytokine responses to coarse and fine particulate matter from the great California wildfires of 2008. Inhalation Toxicology. 22: 561-70. PMID 20388000 DOI: 10.3109/08958370903571849  0.351
2010 Bratt JM, Franzi LM, Linderholm AL, O'Roark EM, Kenyon NJ, Last JA. Arginase inhibition in airways from normal and nitric oxide synthase 2-knockout mice exposed to ovalbumin. Toxicology and Applied Pharmacology. 242: 1-8. PMID 19800904 DOI: 10.1016/J.Taap.2009.09.018  0.789
2009 Zeki AA, Franzi L, Last J, Kenyon NJ. Simvastatin inhibits airway hyperreactivity: implications for the mevalonate pathway and beyond. American Journal of Respiratory and Critical Care Medicine. 180: 731-40. PMID 19608720 DOI: 10.1164/rccm.200901-0018OC  0.416
2009 Bratt JM, Franzi LM, Linderholm AL, Last MS, Kenyon NJ, Last JA. Arginase enzymes in isolated airways from normal and nitric oxide synthase 2-knockout mice exposed to ovalbumin. Toxicology and Applied Pharmacology. 234: 273-80. PMID 19027033 DOI: 10.1016/J.Taap.2008.10.007  0.801
2008 Kenyon NJ, Bratt JM, Linderholm AL, Last MS, Last JA. Arginases I and II in lungs of ovalbumin-sensitized mice exposed to ovalbumin: sources and consequences. Toxicology and Applied Pharmacology. 230: 269-75. PMID 18439639 DOI: 10.1016/J.Taap.2008.03.004  0.799
2008 Wegesser TC, Last JA. Lung response to coarse PM: bioassay in mice. Toxicology and Applied Pharmacology. 230: 159-66. PMID 18384828 DOI: 10.1016/j.taap.2008.02.013  0.344
2007 Mathrani VC, Kenyon NJ, Zeki A, Last JA. Mouse models of asthma: can they give us mechanistic insights into the role of nitric oxide? Current Medicinal Chemistry. 14: 2204-13. PMID 17691958 DOI: 10.2174/092986707781389628  0.717
2006 Kenyon NJ, Last MS, Eiserich JP, Morrissey BM, Temple LM, Last JA. Differentiation of the roles of NO from airway epithelium and inflammatory cells in ozone-induced lung inflammation. Toxicology and Applied Pharmacology. 215: 250-9. PMID 16643973 DOI: 10.1016/J.Taap.2006.03.005  0.448
2005 Lee K, Smith JL, Last JA. Absence of respiratory inflammatory reaction of elemental sulfur using the California Pesticide Illness Database and a mouse model. Journal of Agromedicine. 10: 41-7. PMID 16537315 DOI: 10.1300/J096v10n03_05  0.326
2005 Last JA, Gohil K, Mathrani VC, Kenyon NJ. Systemic responses to inhaled ozone in mice: cachexia and down-regulation of liver xenobiotic metabolizing genes. Toxicology and Applied Pharmacology. 208: 117-26. PMID 16183385 DOI: 10.1016/J.Taap.2005.02.001  0.692
2005 Kenyon NJ, Last JA. Reversible and irreversible airway inflammation and fibrosis in mice exposed to inhaled ovalbumin Inflammation Research. 54: 57-65. PMID 15750712 DOI: 10.1007/s00011-004-1325-6  0.492
2004 Last JA, Ward R, Temple L, Pinkerton KE, Kenyon NJ. Ovalbumin-induced airway inflammation and fibrosis in mice also exposed to ultrafine particles. Inhalation Toxicology. 16: 93-102. PMID 15204782 DOI: 10.1080/08958370490265077  0.481
2004 Last JA, Ward R, Temple L, Kenyon NJ. Ovalbumin-induced airway inflammation and fibrosis in mice also exposed to ozone. Inhalation Toxicology. 16: 33-43. PMID 14744663 DOI: 10.1080/08958370490258237  0.478
2003 Kenyon NJ, Ward RW, McGrew G, Last JA. TGF-β1 causes airway fibrosis and increased collagen I and III mRNA in mice Thorax. 58: 772-777. PMID 12947136 DOI: 10.1136/thorax.58.9.772  0.319
2003 Kenyon NJ, Gohil K, Last JA. Susceptibility to ovalbumin-induced airway inflammation and fibrosis in inducible nitric oxide synthetase-deficient mice: mechanisms and consequences. Toxicology and Applied Pharmacology. 191: 2-11. PMID 12915099 DOI: 10.1016/S0041-008X(03)00227-8  0.406
2003 Gohil K, Cross CE, Last JA. Ozone-induced disruptions of lung transcriptomes. Biochemical and Biophysical Research Communications. 305: 719-28. PMID 12763052 DOI: 10.1016/S0006-291X(03)00815-5  0.358
2003 Kenyon NJ, Ward RW, Last JA. Airway fibrosis in a mouse model of airway inflammation. Toxicology and Applied Pharmacology. 186: 90-100. PMID 12639500 DOI: 10.1016/S0041-008X(02)00025-X  0.506
2002 Kenyon NJ, van der Vliet A, Schock BC, Okamoto T, McGrew GM, Last JA. Susceptibility to ozone-induced acute lung injury in iNOS-deficient mice. American Journal of Physiology. Lung Cellular and Molecular Physiology. 282: L540-5. PMID 11839550 DOI: 10.1152/ajplung.00297.2001  0.444
2001 Samimi A, Last JA. Mechanism of inhibition of lysyl hydroxylase activity by the organophosphates malathion and malaoxon. Toxicology and Applied Pharmacology. 176: 181-6. PMID 11714250 DOI: 10.1006/taap.2001.9275  0.512
2001 Samimi A, Last JA. Inhibition of lysyl hydroxylase by malathion and malaoxon. Toxicology and Applied Pharmacology. 172: 203-9. PMID 11312648 DOI: 10.1006/taap.2001.9147  0.558
1995 Last JA, Sun WM, Witschi H. Ozone, NO, and NO2: oxidant air pollutants and more. Environmental Health Perspectives. 179-84. PMID 7705295 DOI: 10.1289/ehp.94102s10179  0.33
1992 Gelzleichter TR, Witschi H, Last JA. Concentration-response relationships of rat lungs to exposure to oxidant air pollutants: a critical test of Haber's Law for ozone and nitrogen dioxide. Toxicology and Applied Pharmacology. 112: 73-80. PMID 1733050 DOI: 10.1016/0041-008X(92)90281-V  0.303
1992 Gelzleichter TR, Witschi H, Last JA. Synergistic interaction of nitrogen dioxide and ozone on rat lungs: acute responses. Toxicology and Applied Pharmacology. 116: 1-9. PMID 1529441 DOI: 10.1016/0041-008X(92)90137-H  0.31
1990 Reiser KM, Tryka AF, Lindenschmidt RC, Last JA, Witschi HR. Changes in collagen cross-linking in bleomycin-induced pulmonary fibrosis. Journal of Biochemical Toxicology. 1: 83-91. PMID 2482891 DOI: 10.1002/jbt.2570010109  0.327
1990 Last JA, King TE, Nerlich AG, Reiser KM. Collagen cross-linking in adult patients with acute and chronic fibrotic lung disease. Molecular markers for fibrotic collagen. The American Review of Respiratory Disease. 141: 307-13. PMID 2301849 DOI: 10.1164/ajrccm/141.2.307  0.31
1990 Last JA, Gerriets JE, Armstrong LC, Gelzleichter TR, Reiser KM. Hydroxylation of collagen by lungs of rats administered bleomycin. American Journal of Respiratory Cell and Molecular Biology. 2: 543-8. PMID 1693282 DOI: 10.1165/ajrcmb/2.6.543  0.3
1987 Last JA, Warren DL, Pecquet-Goad E, Witschi H. Modification by ozone of lung tumor development in mice. Journal of the National Cancer Institute. 78: 149-54. PMID 3467123 DOI: 10.1093/jnci/78.1.149  0.349
1985 Last JA, Hyde DM, Chang DP. A mechanism of synergistic lung damage by ozone and a respirable aerosol. Experimental Lung Research. 7: 223-35. PMID 6525988 DOI: 10.3109/01902148409087915  0.326
1983 Last JA, Gerriets JE, Hyde DM. Synergistic effects on rat lungs of mixtures of oxidant air pollutants (ozone or nitrogen dioxide) and respirable aerosols. The American Review of Respiratory Disease. 128: 539-44. PMID 6614649 DOI: 10.1164/Arrd.1983.128.3.539  0.318
1981 Cross CE, Hesterberg TW, Reiser KM, Last JA. Ozone toxicity as a model of lung fibrosis. Chest. 80: 52-4. PMID 7249741 DOI: 10.1378/chest.80.1_Supplement.52S  0.305
1981 Dubick MA, Rucker RB, Last JA, Lollini LO, Cross CE. Elastin turnover in murine lung after repeated ozone exposure. Toxicology and Applied Pharmacology. 58: 203-10. PMID 7245196 DOI: 10.1016/0041-008X(81)90424-5  0.306
1981 Dubick MA, Rucker RB, Cross CE, Last JA. Elastin metabolism in rodent lung. Biochimica Et Biophysica Acta. 672: 303-6. PMID 7213816 DOI: 10.1016/0304-4165(81)90297-X  0.323
1979 Last JA, Greenberg DB, Castleman WL. Ozone-induced alterations in collagen metabolism of rat lungs Toxicology and Applied Pharmacology. 51: 247-258. PMID 531890 DOI: 10.1016/0041-008X(79)90467-8  0.306
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