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R. Bruce Merrifield - Publications

Affiliations: 
Rockefeller University, New York, NY, United States 
Area:
Biochemistry
Website:
http://nobelprize.org/nobel_prizes/chemistry/laureates/1984/merrifield.html

125 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2005 Barany MJ, Hammer RP, Merrifield RB, Barany G. Efficient synthesis of 1,2,4-dithiazolidine-3,5-diones [dithiasuccinoyl-amines] from bis(chlorocarbonyl)disulfane plus bis(trimethylsilyl)amines. Journal of the American Chemical Society. 127: 508-9. PMID 15643859 DOI: 10.1021/ja0455446  1
2002 Unson CG, Wu CR, Jiang Y, Yoo B, Cheung C, Sakmar TP, Merrifield RB. Roles of specific extracellular domains of the glucagon receptor in ligand binding and signaling. Biochemistry. 41: 11795-803. PMID 12269822 DOI: 10.1021/bi025711j  1
2001 Jiang Y, Cypess AM, Muse ED, Wu CR, Unson CG, Merrifield RB, Sakmar TP. Glucagon receptor activates extracellular signal-regulated protein kinase 1/2 via cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 98: 10102-7. PMID 11517300 DOI: 10.1073/pnas.131200398  1
2001 Robinson NE, Robinson AB, Merrifield RB. Mass spectrometric evaluation of synthetic peptides as primary structure models for peptide and protein deamidation. The Journal of Peptide Research : Official Journal of the American Peptide Society. 57: 483-93. PMID 11437952 DOI: 10.1034/j.1399-3011.2001.00863.x  1
2000 Unson CG, Wu CR, Sakmar TP, Merrifield RB. Selective stabilization of the high affinity binding conformation of glucagon receptor by the long splice variant of Galpha(s). The Journal of Biological Chemistry. 275: 21631-8. PMID 10791965 DOI: 10.1074/jbc.M002093200  1
1999 Marassi FM, Opella SJ, Juvvadi P, Merrifield RB. Orientation of cecropin A helices in phospholipid bilayers determined by solid-state NMR spectroscopy. Biophysical Journal. 77: 3152-5. PMID 10585936 DOI: 10.1016/S0006-3495(99)77145-6  1
1999 Juvvadi P, Vunnam S, Yoo B, Merrifield RB. Structure-activity studies of normal and retro pig cecropin-melittin hybrids. The Journal of Peptide Research : Official Journal of the American Peptide Society. 53: 244-51. PMID 10231712 DOI: 10.1034/j.1399-3011.1999.00020.x  1
1998 Unson CG, Wu CR, Cheung CP, Merrifield RB. Positively charged residues at positions 12, 17, and 18 of glucagon ensure maximum biological potency. The Journal of Biological Chemistry. 273: 10308-12. PMID 9553084 DOI: 10.1074/jbc.273.17.10308  1
1998 Vunnam S, Juvvadi P, Rotondi KS, Merrifield RB. Synthesis and study of normal, enantio, retro, and retroenantio isomers of cecropin A-melittin hybrids, their end group effects and selective enzyme inactivation. The Journal of Peptide Research : Official Journal of the American Peptide Society. 51: 38-44. PMID 9495589  1
1997 Vunnam S, Juvvadi P, Merrifield RB. Synthesis and antibacterial action of cecropin and proline-arginine-rich peptides from pig intestine. The Journal of Peptide Research : Official Journal of the American Peptide Society. 49: 59-66. PMID 9128101  1
1997 Durvasula RV, Gumbs A, Panackal A, Kruglov O, Aksoy S, Merrifield RB, Richards FF, Beard CB. Prevention of insect-borne disease: an approach using transgenic symbiotic bacteria. Proceedings of the National Academy of Sciences of the United States of America. 94: 3274-8. PMID 9096383 DOI: 10.1073/pnas.94.7.3274  1
1996 Juvvadi P, Vunnam S, Merrifield EL, Boman HG, Merrifield RB. Hydrophobic effects on antibacterial and channel-forming properties of cecropin A-melittin hybrids. Journal of Peptide Science : An Official Publication of the European Peptide Society. 2: 223-32. PMID 9231329 DOI: 10.1002/psc.63  1
1996 Unson CG, Cypess AM, Wu CR, Goldsmith PK, Merrifield RB, Sakmar TP. Antibodies against specific extracellular epitopes of the glucagon receptor block glucagon binding. Proceedings of the National Academy of Sciences of the United States of America. 93: 310-5. PMID 8552628 DOI: 10.1073/pnas.93.1.310  1
1996 Juvvadi P, Vunnam S, Merrifield RB. Synthetic melittin, its enantio, retro, and retroenantio isomers, and selected chimeric analogs: Their antibacterial, hemolytic, and lipid bilayer action Journal of the American Chemical Society. 118: 8989-8997. DOI: 10.1021/ja9542911  1
1995 Merrifield EL, Mitchell SA, Ubach J, Boman HG, Andreu D, Merrifield RB. D-enantiomers of 15-residue cecropin A-melittin hybrids. International Journal of Peptide and Protein Research. 46: 214-20. PMID 8537174  1
1995 Merrifield RB, Juvvadi P, Andreu D, Ubach J, Boman A, Boman HG. Retro and retroenantio analogs of cecropin-melittin hybrids. Proceedings of the National Academy of Sciences of the United States of America. 92: 3449-53. PMID 7724582  1
1995 Unson CG, Cypess AM, Kim HN, Goldsmith PK, Carruthers CJ, Merrifield RB, Sakmar TP. Characterization of deletion and truncation mutants of the rat glucagon receptor. Seven transmembrane segments are necessary for receptor transport to the plasma membrane and glucagon binding. The Journal of Biological Chemistry. 270: 27720-7. PMID 7499239 DOI: 10.1074/jbc.270.46.27720  1
1994 Unson CG, Merrifield RB. Identification of an essential serine residue in glucagon: implication for an active site triad. Proceedings of the National Academy of Sciences of the United States of America. 91: 454-8. PMID 8290548  1
1994 Unson CG, Wu CR, Merrifield RB. Roles of aspartic acid 15 and 21 in glucagon action: receptor anchor and surrogates for aspartic acid 9. Biochemistry. 33: 6884-7. PMID 8204623  0.68
1994 Unson CG, Wu CR, Fitzpatrick KJ, Merrifield RB. Multiple-site replacement analogs of glucagon. A molecular basis for antagonist design. The Journal of Biological Chemistry. 269: 12548-51. PMID 8175663  1
1994 Merrifield RB, Merrifield EL, Juvvadi P, Andreu D, Boman HG. Design and synthesis of antimicrobial peptides. Ciba Foundation Symposium. 186: 5-20; discussion 20-. PMID 7768157  1
1993 Unson CG, Macdonald D, Merrifield RB. The role of histidine-1 in glucagon action. Archives of Biochemistry and Biophysics. 300: 747-50. PMID 8382034 DOI: 10.1006/abbi.1993.1103  1
1993 Kaiser E, Picart F, Kubiak T, Tam JP, Merrifield RB. Selective deprotection of the Nα-tert-butyloxycarbonyl group in solid phase peptide synthesis with chlorotrimethylsilane and phenol Journal of Organic Chemistry. 58: 5167-5175.  1
1992 Andreu D, Ubach J, Boman A, WÃ¥hlin B, Wade D, Merrifield RB, Boman HG. Shortened cecropin A-melittin hybrids. Significant size reduction retains potent antibiotic activity. Febs Letters. 296: 190-4. PMID 1733777 DOI: 10.1016/0014-5793(92)80377-S  1
1992 Wade D, Andreu D, Mitchell SA, Silveira AM, Boman A, Boman HG, Merrifield RB. Antibacterial peptides designed as analogs or hybrids of cecropins and melittin. International Journal of Peptide and Protein Research. 40: 429-36. PMID 1483838  1
1991 Unson CG, Macdonald D, Ray K, Durrah TL, Merrifield RB. Position 9 replacement analogs of glucagon uncouple biological activity and receptor binding. The Journal of Biological Chemistry. 266: 2763-6. PMID 1847133  1
1990 Wade D, Boman A, WÃ¥hlin B, Drain CM, Andreu D, Boman HG, Merrifield RB. All-D amino acid-containing channel-forming antibiotic peptides. Proceedings of the National Academy of Sciences of the United States of America. 87: 4761-5. PMID 1693777  1
1989 Boman HC, Boman IA, Andreu D, Li ZQ, Merrifield RB, Schlenstedt G, Zimmermann R. Chemical synthesis and enzymic processing of precursor forms of cecropins A and B. The Journal of Biological Chemistry. 264: 5852-60. PMID 2925637  1
1989 Fink J, Boman A, Boman HG, Merrifield RB. Design, synthesis and antibacterial activity of cecropin-like model peptides. International Journal of Peptide and Protein Research. 33: 412-21. PMID 2777475  1
1989 Boman HG, Wade D, Boman IA, WÃ¥hlin B, Merrifield RB. Antibacterial and antimalarial properties of peptides that are cecropin-melittin hybrids. Febs Letters. 259: 103-6. PMID 2689223 DOI: 10.1016/0014-5793(89)81505-4  1
1989 Unson CG, Gurzenda EM, Merrifield RB. Biological activities of des-His1[Glu9]glucagon amide, a glucagon antagonist. Peptides. 10: 1171-7. PMID 2560175 DOI: 10.1016/0196-9781(89)90010-7  1
1989 Unson CG, Gurzenda EM, Iwasa K, Merrifield RB. Glucagon antagonists: contribution to binding and activity of the amino-terminal sequence 1-5, position 12, and the putative alpha-helical segment 19-27. The Journal of Biological Chemistry. 264: 789-94. PMID 2536024  1
1989 Fink J, Merrifield RB, Boman A, Boman HG. The chemical synthesis of cecropin D and an analog with enhanced antibacterial activity. The Journal of Biological Chemistry. 264: 6260-7. PMID 2495282  1
1989 Stenflo J, Holme E, Lindstedt S, Chandramouli N, Huang LH, Tam JP, Merrifield RB. Hydroxylation of aspartic acid in domains homologous to the epidermal growth factor precursor is catalyzed by a 2-oxoglutarate-dependent dioxygenase. Proceedings of the National Academy of Sciences of the United States of America. 86: 444-7. PMID 2492106  1
1989 Berg RH, Almdal K, Pedersen WB, Holm A, Tam JP, Merrifield RB. Long-chain polystyrene-grafted polyethylene film matrix: a new support-phase peptide synthesis Journal of the American Chemical Society. 111: 8024-8026.  1
1988 Li ZQ, Merrifield RB, Boman IA, Boman HG. Effects on electrophoretic mobility and antibacterial spectrum of removal of two residues from synthetic sarcotoxin IA and addition of the same residues to cecropin B. Febs Letters. 231: 299-302. PMID 3360136 DOI: 10.1016/0014-5793(88)80837-8  1
1988 Merrifield RB, Singer J, Chait BT. Mass spectrometric evaluation of synthetic peptides for deletions and insertions. Analytical Biochemistry. 174: 399-414. PMID 3239745 DOI: 10.1016/0003-2697(88)90039-5  1
1988 Steiner H, Andreu D, Merrifield RB. Binding and action of cecropin and cecropin analogues: antibacterial peptides from insects. Biochimica Et Biophysica Acta. 939: 260-6. PMID 3128324 DOI: 10.1016/0005-2736(88)90069-7  1
1988 Kofod H, Unson CG, Merrifield RB. Potentiation of glucose-induced insulin release in islets by desHis1[Glu9]glucagon amide. International Journal of Peptide and Protein Research. 32: 436-40. PMID 3073146  1
1988 Tam JP, Riemen MW, Merrifield RB. Mechanisms of aspartimide formation: the effects of protecting groups, acid, base, temperature and time. Peptide Research. 1: 6-18. PMID 2980781  1
1988 Kofod H, Andreu D, Thams P, Merrifield RB, Hedeskov CJ, Hansen B, Lernmark A. Insulin release by glucagon and secretin: studies with secretin-glucagon hybrids. The American Journal of Physiology. 254: E454-8. PMID 2833112  1
1988 Christensen B, Fink J, Merrifield RB, Mauzerall D. Channel-forming properties of cecropins and related model compounds incorporated into planar lipid membranes. Proceedings of the National Academy of Sciences of the United States of America. 85: 5072-6. PMID 2455891  1
1988 Kaiser E, Tam JP, Kubiak TM, Merrifield RB. Chlorotrimethylsilane-phenol as a mild deprotection reagent for the tert-butyl based protecting groups in peptide synthesis Tetrahedron Letters. 29: 303-306. DOI: 10.1016/S0040-4039(00)80080-5  1
1987 Murphy J, Zhang WJ, Macaulay W, Fasman G, Merrifield RB. The relation of predicted structure to observed conformation and activity of glucagon analogs containing replacements at positions 19, 22, and 23. The Journal of Biological Chemistry. 262: 17304-12. PMID 3693354  1
1987 Lu GS, Mojsov S, Merrifield RB. Synthesis and hormonal activity of [Tyr22] glucagon and [desHis1, Tyr22] glucagon. International Journal of Peptide and Protein Research. 29: 545-57. PMID 3454664  1
1987 Wang SS, Chen ST, Wang KT, Merrifield RB. 4-Methoxybenzyloxycarbonyl amino acids in solid phase peptide synthesis. International Journal of Peptide and Protein Research. 30: 662-7. PMID 3436702  1
1987 Kubiak T, Whitney DB, Merrifield RB. Synthetic peptides VH(27-68) and VH(16-68) of the myeloma immunoglobulin M603 heavy chain and their association with the natural light chain to form an antigen binding site. Biochemistry. 26: 7849-55. PMID 3122833  1
1987 Unson CG, Andreu D, Gurzenda EM, Merrifield RB. Synthetic peptide antagonists of glucagon. Proceedings of the National Academy of Sciences of the United States of America. 84: 4083-7. PMID 3035568  1
1987 Andreu D, Merrifield RB. Glucagon antagonists. Synthesis and inhibitory properties of Asp3-containing glucagon analogs. European Journal of Biochemistry / Febs. 164: 585-90. PMID 3032623  1
1987 Trimble ER, Bruzzone R, Biden TJ, Meehan CJ, Andreu D, Merrifield RB. Secretin stimulates cyclic AMP and inositol trisphosphate production in rat pancreatic acinar tissue by two fully independent mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 84: 3146-50. PMID 2437575 DOI: 10.1073/pnas.84.10.3146  1
1986 Chandramouli N, Bhargava KK, Incefy GS, Modak MJ, Merrifield RB. Solid phase synthesis of thymosin beta 9. International Journal of Peptide and Protein Research. 28: 536-41. PMID 3818171  1
1986 Heath WF, Merrifield RB. A synthetic approach to structure-function relationships in the murine epidermal growth factor molecule. Proceedings of the National Academy of Sciences of the United States of America. 83: 6367-71. PMID 3018729  1
1986 Tam JP, Heath WF, Merrifield RB. Mechanisms for the removal of benzyl protecting groups in synthetic peptides by Trifluoromethanesulfonic Acid-Trifluoroacetic Acid-Dimethyl Sulfide Journal of the American Chemical Society. 108: 5242-5251.  1
1986 Heath WF, Tam JP, Merrifield RB. Improved deprotection of cysteine-containing peptides in HF International Journal of Peptide and Protein Research. 28: 498-507.  1
1985 Tam JP, Merrifield RB. Solid phase synthesis of gastrin I. Comparison of methods utilizing strong acid for deprotection and cleavage. International Journal of Peptide and Protein Research. 26: 262-73. PMID 4055234  1
1985 Andreu D, Merrifield RB, Steiner H, Boman HG. N-terminal analogues of cecropin A: synthesis, antibacterial activity, and conformational properties. Biochemistry. 24: 1683-8. PMID 3924096  1
1985 van Hofsten P, Faye I, Kockum K, Lee JY, Xanthopoulos KG, Boman IA, Boman HG, Engström A, Andreu D, Merrifield RB. Molecular cloning, cDNA sequencing, and chemical synthesis of cecropin B from Hyalophora cecropia. Proceedings of the National Academy of Sciences of the United States of America. 82: 2240-3. PMID 3857578  1
1985 Boman HG, Faye I, von Hofsten P, Kockum K, Lee JY, Xanthopoulos KG, Bennich H, Engström A, Merrifield RB, Andreu D. On the primary structures of lysozyme, cecropins and attacins from Hyalophora cecropia. Developmental and Comparative Immunology. 9: 551-8. PMID 3840100 DOI: 10.1016/0145-305X(85)90018-7  1
1985 Andreu D, Aschauer H, Kreil G, Merrifield RB. Solid-phase synthesis of PYLa and isolation of its natural counterpart, PGLa [PYLa-(4-24)] from skin secretion of Xenopus laevis. European Journal of Biochemistry / Febs. 149: 531-5. PMID 3839186  1
1984 Mojsov S, Merrifield RB. An improved synthesis of crystalline mammalian glucagon. European Journal of Biochemistry / Febs. 145: 601-5. PMID 6510418  1
1984 Whitney DB, Tam JP, Merrifield RB. A new base-catalyzed cleavage reaction for the preparation of protected peptides Tetrahedron. 40: 4237-4244. DOI: 10.1016/S0040-4020(01)98798-8  1
1984 Sarin V, Kent SBH, Mitchell AR, Merrifield RB. GENERAL APPROACH TO THE QUANTITATION OF SYNTHETIC EFFICIENCY IN SOLID-PHASE PEPTIDE SYNTHESIS AS A FUNCTION OF CHAIN LENGTH Journal of the American Chemical Society. 106: 7845-7850.  1
1983 Kent SB, Merrifield RB. Chemical mechanism to account for artifactual formation of shortened peptides with free alpha-amino groups in solid phase peptide synthesis. International Journal of Peptide and Protein Research. 22: 57-65. PMID 6885250  1
1983 Tam JP, Heath WF, Merrifield RB. SN 1 and SN 2 mechanisms for the deprotection of synthetic peptides by hydrogen fluoride. Studies to minimize the tyrosine alkylation side reaction. International Journal of Peptide and Protein Research. 21: 57-65. PMID 6826283  1
1983 Voss C, Dimarchi R, Whitney DB, Tjoeng FS, Merrifield RB, Tam JP. Synthesis of the protected tridecapeptide (56-68) of the VH domain of mouse myeloma immunoglobulin M603 and its reattachment to resin supports. International Journal of Peptide and Protein Research. 22: 204-13. PMID 6618764  1
1983 Andreu D, Merrifield RB, Steiner H, Boman HG. Solid-phase synthesis of cecropin A and related peptides. Proceedings of the National Academy of Sciences of the United States of America. 80: 6475-9. PMID 6579533  1
1983 Tam JP, Heath WF, Merrifield RB. SN2 deprotection of synthetic peptides with a low concentration of HF in dimethyl sulfide: Evidence and application in peptide synthesis Journal of the American Chemical Society. 105: 6442-6455.  1
1983 Bhargava KK, Sarin VK, Trang NL, Cerami A, Merrifield RB. Synthesis of a cyclic analogue of oxidized glutathione by an intersite reaction in a swollen polymer network Journal of the American Chemical Society. 105: 3247-3251.  1
1982 Kumar GK, Bahler CR, Wood HG, Merrifield RB. The amino acid sequences of the biotinyl subunit essential for the association of transcarboxylase. The Journal of Biological Chemistry. 257: 13828-34. PMID 7142178  1
1982 Dimarchi RD, Tam JP, Kent SB, Merrifield RB. Weak acid-catalyzed pyrrolidone carboxylic acid formation from glutamine during solid phase peptide synthesis. Minimization by rapid coupling. International Journal of Peptide and Protein Research. 19: 88-93. PMID 7118385  1
1982 Merrifield RB, Vizioli LD, Boman HG. Synthesis of the antibacterial peptide cecropin A (1-33). Biochemistry. 21: 5020-31. PMID 6814482  1
1982 Dimarchi RD, Tam JP, Merrifield RB. Solid phase synthesis of the protected 43-55 tridecapeptide of the heavy chain of myeloma immunoglobin M603, employing cyclohexyl ester protection for glutamic acid. International Journal of Peptide and Protein Research. 19: 270-9. PMID 6811468  1
1982 Heath WF, Tam JP, Merrifield RB. Improved deprotection in solid phase peptide synthesis: Deprotection of Ni-formyl-tryptophan to tryptophan in low concentrations of HF in Me2S-p-thiocresol mixtures Journal of the Chemical Society - Series Chemical Communications. 896-897. DOI: 10.1039/C39820000896  1
1982 Tam JP, Heath WF, Merrifield RB. Improved deprotection in solid phase peptide synthesis: quantitative reduction of methionine sulfoxide to methionine during HF cleavage Tetrahedron Letters. 23: 2939-2942. DOI: 10.1016/S0040-4039(00)87499-7  1
1982 Tam JP, Heath WF, Merrifield RB. Improved deprotection in solid phase reptide synthesis: removal of protecting groups from synthetic peptides by an SN2 mechanism with low concentrations of HF in dimethylsulfide Tetrahedron Letters. 23: 4435-4438. DOI: 10.1016/S0040-4039(00)85621-X  1
1982 Isied SS, Kuehn CG, Lyon JM, Merrifield RB. Specific peptide sequences for metal ion coordination. 1. Solid-phase synthesis of cyclo-(gly-his)3 Journal of the American Chemical Society. 104: 2632-2634.  1
1981 Wang SS, Tam JP, Wang BS, Merrifield RB. Enhancement of peptide coupling reactions by 4-dimethylaminopyridine. International Journal of Peptide and Protein Research. 18: 459-67. PMID 7341528  1
1981 Sarin VK, Kent SB, Tam JP, Merrifield RB. Quantitative monitoring of solid-phase peptide synthesis by the ninhydrin reaction. Analytical Biochemistry. 117: 147-57. PMID 7316187 DOI: 10.1016/0003-2697(81)90704-1  1
1981 Mojsov S, Merrifield RB. Solid-phase synthesis of crystalline glucagon. Biochemistry. 20: 2950-6. PMID 7248261  1
1981 Tam JP, DiMarchi RD, Merrifield RB. Design and synthesis of a multi-detachable benzhydrylamine-resin for solid phase peptide synthesis Tetrahedron Letters. 22: 2851-2854. DOI: 10.1016/S0040-4039(01)81767-6  1
1981 Lu GS, Mojsov S, Tam JP, Merrifield RB. Improved synthesis of 4-alkoxybenzyl alcohol resin Journal of Organic Chemistry. 46: 3433-3436.  1
1980 Wang SS, Makofske R, Bach A, Merrifield RB. Automated solid phase synthesis of thymosin alpha 1. International Journal of Peptide and Protein Research. 15: 1-4. PMID 7358454  1
1980 Tam JP, Dimarchi RD, Merrifield RB. Photolabile multi-detachable p-alkoxybenzyl alcohol resin supports for peptide fragment or semi-synthesis. International Journal of Peptide and Protein Research. 16: 412-25. PMID 7216616  1
1980 Wong TW, Merrifield RB. Solid-phase synthesis of thymosin alpha 1 using tert-butyloxycarbonylaminoacyl-4-(oxymethyl)phenylacetamidomethyl-resin. Biochemistry. 19: 3233-8. PMID 7190831  1
1980 Mojsov S, Mitchell AR, Merrifield RB. A quantitative evaluation of methods for coupling asparagine Journal of Organic Chemistry. 45: 555-560.  1
1980 Tam JP, Tjoeng FS, Merrifield RB. Design and synthesis of multidetachable resin supports for solid-phase peptide synthesis Journal of the American Chemical Society. 102: 6117-6127.  1
1980 Barany G, Merrifield RB. Kinetics and mechanism of the thiolytic removal of the dithiasuccinoyl (Dts) amino protecting group Journal of the American Chemical Society. 102: 3084-3095.  1
1980 Sarin VK, Kent SBH, Merrifield RB. Properties of swollen polymer networks. Solvation and swelling of peptide-containing resins in solid-phase peptide synthesis Journal of the American Chemical Society. 102: 5463-5470.  1
1979 Barany G, Merrifield RB. A chromatographic method for the quantitative analysis of the deprotection of dithiasuccinoyl (Dts) amino acids. Analytical Biochemistry. 95: 160-70. PMID 495950 DOI: 10.1016/0003-2697(79)90199-4  1
1979 Kent SB, Mitchell AR, Engelhard M, Merrifield RB. Mechanisms and prevention of trifluoroacetylation in solid-phase peptide synthesis. Proceedings of the National Academy of Sciences of the United States of America. 76: 2180-4. PMID 287055  1
1979 Simon EJ, Bonnet KA, Hiller JM, Rieman MW, Merrifield RB. Opioid activity of synthetic and naturally occurring enkephalin peptides. Biochemical Pharmacology. 28: 3333-7. PMID 230849 DOI: 10.1016/0006-2952(79)90129-1  1
1979 Tjoeng FS, Tam JP, Merrifield RB. Solid phase synthesis of the protected 27--42 hexadecapeptide of the heavy chain from myeloma immunoglobulin M603. Elimination of side reactions associated with glycyl-2-oxypropionyl-resin. International Journal of Peptide and Protein Research. 14: 262-74. PMID 42624  1
1979 Tam JP, Kent SBH, Wong TW, Merrifield RB. Improved synthesis of 4-(Boc-aminoacyloxymethyi)-phenylacetic acids for use in solid phase peptide synthesis Synthesis (Germany). 1979: 955-957. DOI: 10.1055/s-1979-28887  1
1979 Tam JP, Tjoeng FS, Merrifield RB. Multi-detachable resin supports for solid phase fragment synthesis Tetrahedron Letters. 20: 4935-4938. DOI: 10.1016/S0040-4039(01)86754-X  1
1979 Tam JP, Wong TW, Riemen MW, Tjoeng FS, Merrifield RB. Cyclohexyl ester as a new protecting group for aspartyl peptides to minimize aspartimide formation in acidic and basic treatments Tetrahedron Letters. 20: 4033-4036. DOI: 10.1016/S0040-4039(01)86496-0  1
1979 Krieger DE, Vidali G, Erickson BW, Allfrey VG, Merrifield RB. The synthesis of diacetylated histone H4-(1-37) for studies on the mechanism of histone deacetylation Bioorganic Chemistry. 8: 409-427. DOI: 10.1016/0045-2068(79)90044-0  1
1978 Merrifield RB. Biopolymer synthesis on solid supports Pure and Applied Chemistry. 50: 643-653. DOI: 10.1351/pac197850070643  1
1978 Engelhard M, Merrifield RB. Tyrosine protecting groups: Minimization of rearrangement to 3-alkyltyrosine during acidolysis Journal of the American Chemical Society. 100: 3559-3563.  1
1978 Merrifield RB, Bach AE. 9-(2-Sulfo)fluorenylmethyloxycarbonyl chloride, a new reagent for the purification of synthetic peptides Journal of Organic Chemistry. 43: 4808-4816.  1
1978 Mitchell AR, Kent SBH, Engelhard M, Merrifield RB. A new synthetic route to tert-butyloxycarbonylaminoacyl-4-(oxymethyl)phenylacetamidomethyl-resin, an improved support for solid-phase peptide synthesis Journal of Organic Chemistry. 43: 2845-2852.  1
1977 Barany G, Merrifield RB. A new amino protecting group removable by reduction. Chemistry of the dithiasuccinoyl (Dts) function. Journal of the American Chemical Society. 99: 7363-5. PMID 915158  1
1977 Kagan NE, Mauzerall D, Merrifield RB. strati-Bisporphyrins. A novel cyclophane system [6] Journal of the American Chemical Society. 99: 5484-5486. PMID 886108  1
1976 Krieger DE, Erickson BW, Merrifield RB. Affinity purification of synthetic peptides. Proceedings of the National Academy of Sciences of the United States of America. 73: 3160-4. PMID 1067609  1
1976 Mitchell AR, Erickson BW, Ryabtsev MN, Hodges RS, Merrifield RB. Tert-butoxycarbonylaminoacyl-4-(oxymethyl)-phenylacetamidomethyl-resin, a more acid-resistant support for solid-phase peptide synthesis. Journal of the American Chemical Society. 98: 7357-62. PMID 10319  1
1975 Hodges RS, Merrifield RB. Monitoring of solid phase peptide synthesis by an automated spectrophotometric picrate method. Analytical Biochemistry. 65: 241-72. PMID 1130679  1
1975 Hodges RS, Merrifield RB. The role of serine-123 in the activity and specificity of ribonuclease. Reactivation of ribonuclease 1-118 by the synthetic COOH-terminal tetradecapeptide, ribonuclease 111-124, and its O-methylserine and alanine analogs. The Journal of Biological Chemistry. 250: 1231-41. PMID 1112802  1
1974 Krieger DE, Levine R, Merrifield RB, Vidali G, Allfrey VG. Chemical studies of histone acetylation. Substrate specificity of a histone deacetylase from calf thymus nuclei. The Journal of Biological Chemistry. 249: 332-4. PMID 4855628  1
1974 Hodges RS, Merrifield RB. Synthesis of O-methyl-L-serine and Nalpha-tert-butyloxycarbonyl-O-methyl-L-serine. The Journal of Organic Chemistry. 39: 1870-2. PMID 4854587  1
1974 Merrifield RB, Mitchell AR, Clarke JE. Detection and prevention of urethane acylation during solid-phase peptide synthesis by anhydride methods. The Journal of Organic Chemistry. 39: 660-8. PMID 4833502  1
1974 Hodges RS, Merrifield RB. Synthetic study of the effect of tyrosine at position 120 of ribonuclease. International Journal of Peptide and Protein Research. 6: 397-405. PMID 4455636  1
1973 Erickson BW, Merrifield RB. Use of chlorinated benzyloxycarbonyl protecting groups to eliminate N -branching at lysine during solid-phase peptide synthesis. Journal of the American Chemical Society. 95: 3757-63. PMID 4708381  1
1973 Erickson BW, Merrifield RB. Acid stability of several benzylic protecting groups used in solid-phase peptide synthesis. Rearrangement of O-benzyltyrosine to 3-benzyltyrosine. Journal of the American Chemical Society. 95: 3750-6. PMID 4708380  1
1972 Wang SS, Merrifield RB. A solid phase-fragment approach to peptide synthesis. The application of a t-alkyloxycarbonylhydrazide resin and a t-alkyl alcohol resin. International Journal of Peptide and Protein Research. 4: 309-18. PMID 4648858  1
1970 Felix AM, Merrifield RB. Azide solid phase peptide synthesis. Journal of the American Chemical Society. 92: 1385-91. PMID 5414748  1
1969 Wang SS, Merrifield RB. Preparation of some new biphenylisopropyloxycarbonyl amino acids and their application to the solid phase synthesis of a tryptophan-containing heptapeptide of bovine parathyroid hormone. International Journal of Protein Research. 1: 235-44. PMID 5408675  1
1968 Takashima H, Du Vigneaud V, Merrifield RB. The synthesis of deamino-oxytocin by the solid phase method. Journal of the American Chemical Society. 90: 1323-5. PMID 5636536  1
1963 WOOLLEY DW, MERRIFIELD RB. Anomalies of the structural specificity of peptides. Annals of the New York Academy of Sciences. 104: 161-71. PMID 14001849  1
1958 WOOLLEY DW, MERRIFIELD RB. Specificity of peptides; new aspects of the specificity of peptides with vitamin and hormone action are described. Science (New York, N.Y.). 128: 238-40. PMID 13568768  1
1955 MERRIFIELD RB, WOOLLEY DW. Isolation and determination of structure of a peptide with strepogenin activity. Archives of Biochemistry and Biophysics. 56: 265-6. PMID 14377574  1
1955 WOOLLEY DW, MERRIFIELD RB, RESSLER C, DU VIGNEAUD V. Strepogenin activity of synthetic peptides related to oxytocin. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 89: 669-73. PMID 13254861  1
1954 WOOLLEY D, MERRIFIELD RB. [Demonstration of a new action of thiamine by the use of pyrithiamine]. Bulletin De La SociéTé De Chimie Biologique. 36: 1207-12. PMID 13230775  0.92
1952 MERRIFIELD RB, WOOLLEY DW. The structure and microbiological activity of some dinucleotides isolated from yeast ribonucleic acid. The Journal of Biological Chemistry. 197: 521-37. PMID 12981083  1
1950 MERRIFIELD RB, DUNN MS. The microbiological determination of pyrimidines with lactobacilli. The Journal of Biological Chemistry. 186: 331-41. PMID 14778836  0.96
1949 DUNN MS, McCLURE LE, MERRIFIELD RB. The determination of proline in protein hydrolysates with Lactobacillus brevis. The Journal of Biological Chemistry. 179: 11-8. PMID 18119214  0.96
1948 MERRIFIELD RB, DUNN MS. Microbiological determination of cytosine, uracil and thymine. Archives of Biochemistry. 16: 339-41. PMID 18903702  0.96
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