cached image

Jerome Karle - Publications

Affiliations: 
US Naval Research Laboratory 
Area:
Physical chemistry, structural chemistry
Website:
http://nobelprize.org/nobel_prizes/chemistry/laureates/1985/karle.html

126 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Huang L, Massa L, Karle J. Discovery of energetic materials by a theoretical method (DEMTM) International Journal of Energetic Materials and Chemical Propulsion. 10: 33-44. DOI: 10.1615/IntJEnergeticMaterialsChemProp.2011003997  0.96
2010 Massa L, Matta CF, Yonath A, Karle J. Quantum Transition State for Peptide Bond Formation in the Ribosome Quantum Biochemistry. 499-515. DOI: 10.1002/9783527629213.ch16  0.96
2010 Huang L, Massa L, Karle J. Quantum Kernels and Quantum Crystallography: Applications in Biochemistry Quantum Biochemistry. 1-60. DOI: 10.1002/9783527629213.ch1  0.96
2009 Huang L, Massa L, Karle I, Karle J. Calculation of strong and weak interactions in TDA1 and RangDP52 by the kernel energy method. Proceedings of the National Academy of Sciences of the United States of America. 106: 3664-9. PMID 19234108 DOI: 10.1073/pnas.0900403106  0.96
2009 Huang L, Massa L, Karle J. Kernel energy method applied to vesicular stomatitis virus nucleoprotein. Proceedings of the National Academy of Sciences of the United States of America. 106: 1731-6. PMID 19188588 DOI: 10.1073/pnas.0811959106  0.96
2008 Huang L, Massa L, Karle J. Calculated interactions of a nitro group with aromatic rings of crystalline picryl bromide. Proceedings of the National Academy of Sciences of the United States of America. 105: 13720-3. PMID 18780785 DOI: 10.1073/pnas.0807218105  0.96
2008 Huang L, Massa L, Karle J. The kernel energy method of quantum mechanical approximation carried to fourth-order terms. Proceedings of the National Academy of Sciences of the United States of America. 105: 1849-54. PMID 18250333 DOI: 10.1073/pnas.0711297105  0.96
2008 Huang L, Massa L, Bernal I, Karle J. The OH-anion acting as an acid. The Journal of Chemical Physics. 128: 024703. PMID 18205462 DOI: 10.1063/1.2821105  0.96
2007 Wallace S, Huang L, Massa L, Mukhopadhyay U, Bernal I, Karle J. The structures of cyclic dihydronium cations. Proceedings of the National Academy of Sciences of the United States of America. 104: 16798-803. PMID 17942671 DOI: 10.1073/pnas.0708249104  0.96
2007 Huang L, Massa L, Karle J. Drug target interaction energies by the kernel energy method in aminoglycoside drugs and ribosomal A site RNA targets. Proceedings of the National Academy of Sciences of the United States of America. 104: 4261-6. PMID 17360512 DOI: 10.1073/pnas.0610533104  0.96
2007 Tang Y, Dong Y, Wittlin S, Charman SA, Chollet J, Chiu FC, Charman WN, Matile H, Urwyler H, Dorn A, Bajpai S, Wang X, Padmanilayam M, Karle JM, Brun R, et al. Weak base dispiro-1,2,4-trioxolanes: potent antimalarial ozonides. Bioorganic & Medicinal Chemistry Letters. 17: 1260-5. PMID 17189686 DOI: 10.1016/j.bmcl.2006.12.007  1
2007 Huang L, Massa L, Karle J. Kernel energy method: The interaction energy of the collagen triple helix Journal of Chemical Theory and Computation. 3: 1337-1341. DOI: 10.1021/ct7000649  0.96
2006 Gindulyte A, Bashan A, Agmon I, Massa L, Yonath A, Karle J. The transition state for formation of the peptide bond in the ribosome. Proceedings of the National Academy of Sciences of the United States of America. 103: 13327-32. PMID 16938893 DOI: 10.1073/pnas.0606027103  0.96
2006 Huang L, Massa L, Karle J. The Kernel Energy Method: application to a tRNA. Proceedings of the National Academy of Sciences of the United States of America. 103: 1233-7. PMID 16432197 DOI: 10.1073/pnas.0510342103  0.96
2006 Huang L, Massa L, Karle J. Kernel energy method: Basis functions and quantum methods International Journal of Quantum Chemistry. 106: 447-457. DOI: 10.1002/qua.20760  0.96
2005 Huang L, Massa L, Karle J. Kernel energy method: application to DNA. Biochemistry. 44: 16747-52. PMID 16342965 DOI: 10.1021/bi051655l  0.96
2005 Huang L, Massa L, Karle J. Kernel energy method: application to insulin. Proceedings of the National Academy of Sciences of the United States of America. 102: 12690-3. PMID 16120673 DOI: 10.1073/pnas.0506378102  0.96
2005 Dong Y, Chollet J, Matile H, Charman SA, Chiu FC, Charman WN, Scorneaux B, Urwyler H, Santo Tomas J, Scheurer C, Snyder C, Dorn A, Wang X, Karle JM, Tang Y, et al. Spiro and dispiro-1,2,4-trioxolanes as antimalarial peroxides: charting a workable structure-activity relationship using simple prototypes. Journal of Medicinal Chemistry. 48: 4953-61. PMID 16033274 DOI: 10.1021/jm049040u  1
2005 Guan J, Zhang Q, Montip G, Karle JM, Ditusa CA, Milhous WK, Skillman DR, Lin AJ. Structure identification and prophylactic antimalarial efficacy of 2-guanidinoimidazolidinedione derivatives. Bioorganic & Medicinal Chemistry. 13: 699-704. PMID 15653337 DOI: 10.1016/j.bmc.2004.10.052  1
2005 Karle I, Karle J. Gas electron diffraction and its influence on the solution of the phase problem in crystal structure determination Structural Chemistry. 16: 5-16. DOI: 10.1007/s11224-005-1075-2  0.96
2004 Tang Y, Dong Y, Karle JM, DiTusa CA, Vennerstrom JL. Synthesis of tetrasubstituted ozonides by the Griesbaum coozonolysis reaction: diastereoselectivity and functional group transformations by post-ozonolysis reactions. The Journal of Organic Chemistry. 69: 6470-3. PMID 15357611 DOI: 10.1021/jo040171c  1
2003 Karle J, Huang L. The glue that holds crystals together: A review Journal of Molecular Structure. 647: 9-16. DOI: 10.1016/S0022-2860(02)00516-1  0.96
2003 Gindulyte A, Massa L, Huang L, Karle J. Decomposition Mechanism of 1,1-Diamino Dinitroethylene (Fox-7): An Overview of the Quantum Chemical Calculation Theoretical and Computational Chemistry. 12: 91-109.  0.96
2002 Karle JM, Karle IL. Crystal structure of (-)-mefloquine hydrochloride reveals consistency of configuration with biological activity. Antimicrobial Agents and Chemotherapy. 46: 1529-34. PMID 11959592 DOI: 10.1128/AAC.46.5.1529-1534.2002  1
2002 Karle JM, Bhattacharjee AK, Vennerstrom JL. Crystal structure of the potent bisquinoline antimalarial agent (±)-trans-N1,N2-bis(7-chloroquinolin-4-yl) cyclohexane-1,2-diamine dimethanesulfonate salt hydrate in relation to its biological properties Journal of Chemical Crystallography. 32: 133-139. DOI: 10.1023/A:1015602002694  1
2002 Wu B, Karle JM, Watkins EB, Avery MA. Toward the total synthesis of pseudolaric acid B. Preparation of a key intermediate by degradation and its use in the reassembly of the natural product Tetrahedron Letters. 43: 4095-4098. DOI: 10.1016/S0040-4039(02)00596-8  1
2001 Huang L, Massa L, Karle J. Quantum crystallography, a developing area of computational chemistry extending to macromolecules Ibm Journal of Research and Development. 45: 409-415. DOI: 10.1016/S0022-2860(98)00555-9  0.96
2000 Bhattacharjee AK, Gupta RK, Ma D, Karle JM. Molecular similarity analysis between insect juvenile hormone and N, N-diethyl-m-toluamide (DEET) analogs may aid design of novel insect repellents. Journal of Molecular Recognition : Jmr. 13: 213-20. PMID 10931558 DOI: 10.1002/1099-1352(200007/08)13:4<213::AID-JMR500>3.0.CO;2-T  1
2000 Panicker B, Karle JM, Avery MA. An unusual reversal of stereoselectivity in a boron mediated aldol reaction: Enantioselective synthesis of the C1-C6 segment of the epothilones Tetrahedron. 56: 7859-7868. DOI: 10.1016/S0040-4020(00)00708-0  1
2000 Karle J. Structural Chemistry: Foreword Structural Chemistry. 11: 91-93.  0.96
1999 Vippagunta SR, Dorn A, Matile H, Bhattacharjee AK, Karle JM, Ellis WY, Ridley RG, Vennerstrom JL. Structural specificity of chloroquine-hematin binding related to inhibition of hematin polymerization and parasite growth. Journal of Medicinal Chemistry. 42: 4630-9. PMID 10579825 DOI: 10.1021/jm9902180  1
1999 Karle JM, Bhattacharjee AK. Stereoelectronic features of the cinchona alkaloids determine their differential antimalarial activity. Bioorganic & Medicinal Chemistry. 7: 1769-74. PMID 10530923 DOI: 10.1016/S0968-0896(99)00120-0  1
1999 Bhattacharjee AK, Karle JM. Stereoelectronic properties of antimalarial artemisinin analogues in relation to neurotoxicity. Chemical Research in Toxicology. 12: 422-8. PMID 10328752 DOI: 10.1021/tx9802116  1
1999 Konnert J, Karle J, Karle IL, Uma K, Balaram P. Isomorphous replacement combined with anomalous dispersion in the linear equations: application to a crystal containing four nonapeptide conformers. Acta Crystallographica. Section D, Biological Crystallography. 55: 448-57. PMID 10089354 DOI: 10.1107/S0907444998011081  0.96
1999 Ma D, Bhattacharjee AK, Gupta RK, Karle JM. Predicting mosquito repellent potency of N,N-diethyl-m-toluamide (DEET) analogs from molecular electronic properties. The American Journal of Tropical Medicine and Hygiene. 60: 1-6. PMID 9988314  1
1999 Gindulyte A, Massa L, Huang L, Karle J. Proposed mechanism of 1,1-diamino-dinitroethylene decomposition: A density functional theory study Journal of Physical Chemistry A. 103: 11045-11051.  0.96
1999 Gindulyté A, Massa L, Huang L, Karle J. Ab initio study of unimolecular decomposition of nitroethylene Journal of Physical Chemistry A. 103: 11040-11044.  0.96
1999 Huang L, Massa L, Karle J. Quantum crystallography applied to crystalline maleic anhydride International Journal of Quantum Chemistry. 73: 439-450.  0.96
1998 Bhattacharjee AK, Karle JM. Functional correlation of molecular electronic properties with potency of synthetic carbinolamine antimalarial agents. Bioorganic & Medicinal Chemistry. 6: 1927-33. PMID 9839022 DOI: 10.1016/S0968-0896(98)00146-1  1
1998 Bhattacharjee AK, Karle JM. Molecular electronic properties to aid the design of reversal agents for multidrug resistance of the antimalarial mefloquine Faseb Journal. 12: A773.  1
1998 Karle J, Huang L, Massa L. Quantum crystallography, a technique for extending the concept of structure Pure and Applied Chemistry. 70: 319-324.  0.96
1997 Karle JM. X-ray crystal structure of the antimalarial agent (-)-halofantrine hydrochloride supports stereospecificity for cardiotoxicity. Antimicrobial Agents and Chemotherapy. 41: 791-4. PMID 9087491  1
1997 Karle J. The role of motivation in scientific research IV: The nature of basic research and its implications Interdisciplinary Science Reviews. 22: 78-84. DOI: 10.1179/isr.1988.13.1.18  0.96
1997 Haraldson CA, Karle JM, Freeman SG, Duvadie RK, Avery MA. The synthesis of 8,8-disubstituted tricyclic analogs of artemisinin Bioorganic and Medicinal Chemistry Letters. 7: 2357-2362. DOI: 10.1016/S0960-894X(97)00432-0  1
1996 Bhattacharjee AK, Karle JM. Molecular electronic properties of a series of 4-quinolinecarbinolamines define antimalarial activity profile. Journal of Medicinal Chemistry. 39: 4622-9. PMID 8917651 DOI: 10.1021/jm960358z  1
1996 Avery MA, Fan P, Karle JM, Bonk JD, Miller R, Goins DK. Structure-activity relationships of the antimalarial agent artemisinin. 3. Total synthesis of (+)-13-carbaartemisinin and related tetra- and tricyclic structures. Journal of Medicinal Chemistry. 39: 1885-97. PMID 8627612 DOI: 10.1021/jm950921y  1
1996 Huang L, Massa L, Karle J. Kernel projector matrices for Leu1-zervamicin International Journal of Quantum Chemistry. 60: 1691-1700.  0.96
1996 Karle JM, Bhattacharjee AK. Trifluoromethyl group disorder in crystalline 2,8-bis(trifluoromethyl)-4-hydroxymethylquinoline Journal of Chemical Crystallography. 26: 615-619.  1
1995 Karle JM, Olmeda R, Freeman SG, Schroeder AC. Quantification of the individual enantiomer plasma concentrations of the candidate antimalarial agent N4-[2,6-dimethoxy-4-methyl-5-[(3-trifluoromethyl)phenoxy]-8-quinolinyl] - 1,4-pentanediamine (WR 238,605). Journal of Chromatography. B, Biomedical Applications. 670: 251-7. PMID 8548015 DOI: 10.1016/0378-4347(95)00166-2  1
1995 Karle J. New approaches to structure analysis. Acta Crystallographica. Section B, Structural Science. 51: 411-5. PMID 7646837 DOI: 10.1107/S0108768195000024  0.96
1995 Avery MA, Fan P, Karle JM, Miller R, Goins K. Replacement of the nonperoxidic trioxane oxygen atom of artemisinin by carbon: Total synthesis of (+)-13-carbaartemisinin and related structures Tetrahedron Letters. 36: 3965-3968. DOI: 10.1016/0040-4039(95)00689-A  1
1994 Karle J. Applications of mathematics to structural chemistry Journal of Chemical Information and Computer Sciences. 34: 381-390.  0.96
1993 Karle JM, Olmeda R, Park AS. Aminosulfhydryl and aminodisulfide compounds enhance binding of the glucocorticoid receptor complex to deoxyribonucleic acid-coated cellulose and to chromatin. The Journal of Steroid Biochemistry and Molecular Biology. 46: 289-97. PMID 9831477 DOI: 10.1016/0960-0760(93)90218-L  1
1993 Karle JM, Olmeda R, Gerena L, Milhous WK. Plasmodium falciparum: role of absolute stereochemistry in the antimalarial activity of synthetic amino alcohol antimalarial agents. Experimental Parasitology. 76: 345-51. PMID 8513873 DOI: 10.1006/expr.1993.1042  1
1993 Acton N, Karle JM, Miller RE. Synthesis and antimalarial activity of some 9-substituted artemisinin derivatives. Journal of Medicinal Chemistry. 36: 2552-7. PMID 8355254  1
1993 Gilardi R, George C, Karle J, Eaton PE, Fisher AM. Aza-analogues of cage compounds: Potential precursors to azacubanes and 1- azahomocubanes Journal of Heterocyclic Chemistry. 30: 1385-1388.  0.96
1992 Karle JM, Karle IL, Gordon RK, Chiang PK. Relationship of three-dimensional structure of muscarinic antagonists to antimuscarinic activity: structure of thiodeacylaprophen hydrochloride. Acta Crystallographica. Section B, Structural Science. 48: 208-13. PMID 1515109 DOI: 10.1107/S0108768191013149  1
1992 Karle JM, Karle IL, Gerena L, Milhous WK. Stereochemical evaluation of the relative activities of the cinchona alkaloids against Plasmodium falciparum. Antimicrobial Agents and Chemotherapy. 36: 1538-44. PMID 1510452  1
1992 Karle JM, Karle IL. Structure of 9-epiquinine hydrochloride dihydrate versus antimalarial activity. Acta Crystallographica. Section C, Crystal Structure Communications. 48: 1975-80. PMID 1457075 DOI: 10.1107/S0108270192002373  1
1992 Karle JM, Karle IL, Leader H, Breuer E, Newman AH, Gordon RK, Chiang PK. Relationship of the crystal structure of γ-N,N-dimethylaminopropyl 2,2-diphenylpropionate hydrochloride to antimuscarinic activity Journal of Crystallographic and Spectroscopic Research. 22: 485-491. DOI: 10.1007/BF01195411  1
1991 Karle J. Direct calculation of atomic coordinates from diffraction intensities: space group P1. Proceedings of the National Academy of Sciences of the United States of America. 88: 10099-103. PMID 1946429  0.96
1991 Karle JM, Karle IL. Crystal structure and molecular structure of mefloquine methylsulfonate monohydrate: implications for a malaria receptor. Antimicrobial Agents and Chemotherapy. 35: 2238-45. PMID 1803997  1
1991 Karle J. Some additional features of one-wavelength anomalous dispersion. Acta Crystallographica. Section a, Foundations of Crystallography. 47: 537-43. PMID 1659427 DOI: 10.1107/S0108767391003914  0.96
1990 Karle JM, Karle IL, Chiang PK. Structural comparison of the potent antimuscarinic agent azaprophen hydrochloride with aprophen hydrochloride and structurally related antimuscarinic agents. Acta Crystallographica. Section B, Structural Science. 46: 215-22. PMID 2344395 DOI: 10.1107/S0108768189010967  1
1989 Karle JM, Olmeda R, Ridder WE, Park AS, Nielsen CJ. Structure-activity relationship of the preservation and restoration of glucocorticoid receptors in rat hepatocytes and rat liver homogenates by sulfhydryl, phosphorothioate and disulfide compounds. Journal of Steroid Biochemistry. 33: 503-13. PMID 2811360 DOI: 10.1016/0022-4731(89)90034-4  1
1989 Karle JM, Karle IL. Crystal and molecular structure of the antimalarial agent enpiroline. Antimicrobial Agents and Chemotherapy. 33: 1081-9. PMID 2782859  1
1989 Karle J. Direct methods in protein crystallography. Acta Crystallographica. Section a, Foundations of Crystallography. 45: 765-81. PMID 2692631 DOI: 10.1107/S0108767389007403  0.96
1989 Karle JM, Karle IL. Structure of the antimalarial halofantrine hydrochloride. Acta Crystallographica. Section C, Crystal Structure Communications. 45: 1248-50. PMID 2604946 DOI: 10.1107/S0108270189002210  1
1989 Karle J. Linear algebraic analyses of structures with one predominant type of anomalous scatterer. Acta Crystallographica. Section a, Foundations of Crystallography. 45: 303-7. PMID 2559755 DOI: 10.1107/S0108767388013042  0.96
1989 Karle J. Macromolecular structure from anomalous dispersion Physics Today. 42: 22-29. DOI: 10.1063/1.881170  0.96
1988 Karle JM, Olmeda R. Rapid and sensitive quantitative analysis of the new antimalarial N4-[2,6-dimethoxy-4-methyl-5-[(3-trifluoromethyl)phenoxy]-8- quinolinyl]-1,4-pentanediamine in plasma by liquid chromatography and electrochemical detection. Journal of Chromatography. 424: 347-56. PMID 3372627 DOI: 10.1016/S0378-4347(00)81111-1  1
1988 Karle JM, Karle IL. Crystal and molecular structure of the antimalarial agent 4-(tert-butyl)-2-(tert-butylaminomethyl)-6-(4-chlorophenyl)phenol dihydrogen phosphate (WR 194,965 phosphate). Antimicrobial Agents and Chemotherapy. 32: 540-6. PMID 3288114  1
1988 Karle JM, Karle IL. Structure of the radiation protection agent S-3-(3-methylaminopropylamino)propylphosphorothioic acid (WR 151,327). Acta Crystallographica. Section C, Crystal Structure Communications. 44: 1218-21. PMID 3271548 DOI: 10.1107/S0108270188002203  1
1988 Karle JM, Karle IL. Redetermination of the crystal and molecular structure of the antimalarial chloroquine bis(dihydrogenphosphate) dihydrate. Acta Crystallographica. Section C, Crystal Structure Communications. 44: 1605-8. PMID 3271099 DOI: 10.1107/S0108270188004652  1
1988 Karle JM, Karle IL. Structure of the radiation protection agent S-2-(3-aminopropylamino)ethylphosphorothioic acid (WR 2721). Acta Crystallographica. Section C, Crystal Structure Communications. 44: 135-8. PMID 2856039 DOI: 10.1107/S0108270187007911  1
1988 Karle J. Origin specification by use of phases Computers and Mathematics With Applications. 16: 397-406. DOI: 10.1016/0898-1221(88)90230-1  0.96
1986 Karle J. Recovering phase information from intensity data. Science (New York, N.Y.). 232: 837-43. PMID 17755964 DOI: 10.1126/science.232.4752.837  0.96
1985 George C, Lowrey AH, Karle J. Molecular structure of 3,3-bisazidomethyloxetane Journal of Molecular Structure. 127: 107-114. DOI: 10.1016/0022-2860(85)80154-X  0.96
1984 Karle J. Crystallographic science Accounts of Chemical Research. 17: 378.  0.96
1983 Camerman A, Mastropaolo D, Karle I, Karle J, Camerman N. Crystal structure of leucine-enkephalin. Nature. 306: 447-50. PMID 6646225 DOI: 10.1038/306447a0  0.96
1981 Karle IL, Karle J. Anomalous dispersion of sulfur in quinidine sulfate, (C(20)H(25)N(2)O(2))(2)SO(4).2H(2)O: Implications for structure analysis. Proceedings of the National Academy of Sciences of the United States of America. 78: 5938-41. PMID 16593097  1
1981 Karle IL, Karle J. Conformation of cyclo(Gly-L-Pro-L-Pro-Gly-L-Pro-L-Pro)(2)Mg complex crystallized from CH(3)CN solution. Proceedings of the National Academy of Sciences of the United States of America. 78: 681-5. PMID 16592971  1
1980 Karle J. Determination of molecular formula and stereoconfiguration of unique steroids by X-ray diffraction analysis. Lipids. 15: 793-7. PMID 7421433 DOI: 10.1007/BF02534033  0.96
1980 Levin W, Buening MK, Wood AW, Chang RL, Kedzierski B, Thakker DR, Boyd DR, Gadaginamath GS, Armstrong RN, Yagi H, Karle JM, Slaga TJ, Jerina DM, Conney AH. An enantiomeric interaction in the metabolism and tumorigenicity of (+)- and (-)-benzo[a]pyrene 7,8-oxide. The Journal of Biological Chemistry. 255: 9067-74. PMID 7410412  1
1979 Buening MK, Levin W, Karle JM, Yagi H, Jerina DM, Conney AH. Tumorigenicity of bay-region epoxides and other derivatives of chrysene and phenanthrene in newborn mice. Cancer Research. 39: 5063-8. PMID 498133  1
1979 Thakker DR, Levin W, Yagi H, Ryan D, Thomas PE, Karle JM, Lehr RE, Jerina DM, Conney AH. Metabolism of benzo[a]anthracene to its tumorigenic 3,4-dihydrodiol. Molecular Pharmacology. 15: 138-53. PMID 423885  1
1979 Buening MK, Levin W, Wood AW, Chang RL, Yagi H, Karle JM, Jerina DM, Conney AH. Tumorigenicity of the dihydrodiols of dibenzo(a,h)anthracene on mouse skin and in newborn mice. Cancer Research. 39: 1310-4. PMID 421214  1
1979 Wood AW, Chang RL, Levin W, Ryan DE, Thomas PE, Mah HD, Karle JM, Yagi H, Jerina DM, Conney AH. Mutagenicity and tumorigenicity of phenanthrene and chrysene epoxides and diol epoxides. Cancer Research. 39: 4069-77. PMID 383279  1
1978 Wislocki PG, Kapitulnik J, Levin W, Lehr R, Schaefer-Ridder M, Karle JM, Jerina DM, Conney AH. Exceptional carcinogenic activity of benz[a]anthracene 3,4-dihydrodiol in the newborn mouse and the bay region theory. Cancer Research. 38: 693-6. PMID 626973  1
1978 Wood AW, Levin W, Thomas PE, Ryan D, Karle JM, Yagi H, Jerina DM, Conney AH. Metabolic activation of dibenzo(a,h)anthracene and its dihydrodiols to bacterial mutagens. Cancer Research. 38: 1967-73. PMID 350381  1
1978 Jeffs PW, Karle JM, Martin NH. Cinnamic acid intermediates as precursors to mesembrine and some observations on the late stages in the biosynthesis of the mesembrine alkaloids Phytochemistry. 17: 719-728. DOI: 10.1016/S0031-9422(00)94215-8  1
1978 Whalen DL, Ross AM, Yagi H, Karle JM, Jerina DM. Stereoelectronic factors in the solvolysis of bay region diol epoxides of polycyclic aromatic hydrocarbons [8] Journal of the American Chemical Society. 100: 5218-5221.  1
1977 Karle IL, Karle JM, Egan W, Zon G, Brandt JA. Absolute configuration of (+)-cyclophosphamide. A crystal and molecular structure determination by X-ray diffraction. Journal of the American Chemical Society. 99: 4803-7. PMID 874232  1
1977 Wood AW, Chang RL, Levin W, Lehr RE, Schaefer-Ridder M, Karle JM, Jerina DM, Conney AH. Mutagenicity and cytotoxicity of benz[a]anthracene diol epoxides and tetrahydro-epoxides: exceptional activity of the bay region 1,2-epoxides Proceedings of the National Academy of Sciences of the United States of America. 74: 2746-2750. PMID 331315 DOI: 10.1073/pnas.74.7.2746  1
1977 Wood AW, Levin W, Chang RL, Lehr RE, Schaefer-Ridder M, Karle JM, Jerina DM, Conney AH. Tumorigenicity of five dihydrodiols of benz(a)anthracene on mouse skin: exceptional activity of benz(a)anthracene 3,4-dihydrodiol. Proceedings of the National Academy of Sciences of the United States of America. 74: 3176-9. PMID 269381 DOI: 10.1073/pnas.74.8.3176  1
1977 Jeffs PW, Karle JM. Late stages in the biosynthesis of mesembrine: Sceletenone as a precursor to the cis-3a-(3,4-dimethoxyphenyl)octahydroindole alkaloids Journal of the Chemical Society, Chemical Communications. 60-61. DOI: 10.1039/C39770000060  1
1977 Karle JM, Mah HD, Jerina DM, Yagi H. Synthesis of dihydrodiols from chrysene and dibenzo[a,h]anthracene Tetrahedron Letters. 18: 4021-4024. DOI: 10.1016/S0040-4039(01)83415-8  1
1975 Moriarty RM, Gopal H, Flippen JL, Karle J. The molecular structure of 7-syn-6-endo-dihydroxybicyclo [2.2.1]heptane 2-endo-carboxylic acid-α-lactone Tetrahedron Letters. 13: 351-354. DOI: 10.1016/S0040-4039(01)84322-7  1
1974 Jeffs PW, Capps T, Johnson DB, Karle JM, Martin NH, Rauckman B. Sceletium alkaloids. VI. Minor alkaloids of S. namaquense and S. strictum Journal of Organic Chemistry. 39: 2703-2710.  1
1973 Hendrickson WA, Karle J. Carp muscle calcium-binding protein. 3. Phase refinement using the tangent formula. The Journal of Biological Chemistry. 248: 3327-34. PMID 4735582  0.96
1973 Hendrickson WA, Love WE, Karle J. Crystal structure analysis of sea lamprey hemoglobin at 2 angstrom resolution. Journal of Molecular Biology. 74: 331-61. PMID 4692855 DOI: 10.1016/0022-2836(73)90377-X  0.96
1972 Oliver JE, Flippen JL, Karle J. X-Ray crystal structure of 3,5-bis(thiocarbamoyl)-1,2,4-dithiazolidines Journal of the Chemical Society, Chemical Communications. 1153-1154. DOI: 10.1039/C39720001153  1
1972 Karle JM, Le Quesne PW. Crystal structure of sewarine N4-methiodide Journal of the Chemical Society, Chemical Communications. 416-417. DOI: 10.1039/C39720000416  1
1972 Karle JM, Karle IL. Correlation of reaction rate acceleration with rotational restriction. Crystal-structure analysis of compounds with a trialkyl lock Journal of the American Chemical Society. 94: 9182-9189.  1
1972 Moriarty RM, Yeh EL, Curtis VA, Yeh CL, Flippen JL, Karle J, Ramey KC. Molecular structures of medium- and large-membered N-methylthiolactams and the dynamics of their syn-anti interconversion [13] Journal of the American Chemical Society. 94: 6871-6872.  1
1971 Moriarty RM, Mukherjee R, Flippen JL, Karle J. Synthesis and X-ray molecular structure of a mesoionic 2-methylene-1,3,4- thiadiazole Journal of the Chemical Society D: Chemical Communications. 1436-1437. DOI: 10.1039/C29710001436  1
1971 Fujimoto Y, Irreverre F, Karle JM, Karle IL, Witkop B. Synthesis and x-ray analysis of cis-3,4-methylene-L-proline, the new natural amino acid from horse chestnuts, and of its trans isomer Journal of the American Chemical Society. 93: 3471-3477.  1
1971 Flippen JL, Karle J. Heptanol as a guest molecule in Dianin's compound Journal of Physical Chemistry. 75: 3566-3567.  1
1970 Karle IL, Karle J. The identification and crystal structure of 7-hydroxy-1,9,10-trimethoxy-4-azabicyclo[5.2.2] undeca-8,10-dien-3-one, a photolysis product from N-chloroacetylmescaline Acta Crystallographica. Section B: Structural Crystallography and Crystal Chemistry. 26: 1276-1282. PMID 5537183 DOI: 10.1107/S0567740870004004  1
1970 Konnert J, Karle IL, Karle J. The structure of dihydrothymidine Acta Crystallographica. Section B: Structural Crystallography and Crystal Chemistry. 26: 770-778. PMID 5536178 DOI: 10.1107/S0567740870003102  1
1970 Karle IL, Gibson JW, Karle J. The conformation and crystal structure of the cyclic polypeptide Gly-Gly-D-Ala-D-Ala-Gly-Gly·3H2O Journal of the American Chemical Society. 92: 3755-3760. PMID 5422773  1
1970 Flippen JL, Karle J, Karle IL. The crystal structure of a versatile organic clathrate. 4-p-hydroxyphenyl-2,2,4-trimethylchroman (Dianin's compound) Journal of the American Chemical Society. 92: 3749-3755.  1
1969 Karle IL, Karle J. The crystal structure of digitoxigenin, C23H34O4 Acta Crystallographica. Section B: Structural Crystallography and Crystal Chemistry. 25: 434-442. PMID 5820224  1
1969 Karle II, Karle J. The structural formula and crystal structure of the O-p-bromobenzoate derivative of batrachotoxinin A, C31H38NO6Br, a frog venom and steroidal alkaloid Acta Crystallographica. Section B: Structural Crystallography and Crystal Chemistry. 25: 428-434. PMID 5820223  1
1968 Karle IL, Karle J. The crystal structure of the alkaloid reserpine, C33H40N209 Acta Crystallographica. Section B: Structural Crystallography and Crystal Chemistry. 24: 81-91. PMID 5694643 DOI: 10.1107/S0567740868001731  1
1968 Tokuyama T, Daly J, Witkop B, Karle IL, Karle J. The structure of batrachotoxinin A, a novel steroidal alkaloid from the Colombian arrow poison frog, Phyllobates aurotaenia. Journal of the American Chemical Society. 90: 1917-8. PMID 5689118  1
1967 Karle J, Estlin JA, Karle IL. The structure of 6-hydroxycrinamine Journal of the American Chemical Society. 89: 6510-6515.  1
1967 Karle J, Karle IL. The crystal and molecular structure of 7-chloro-5- (2,4-dichlorophenyl )-4,5-dihydro1,4-dimethyl-3H-1,4-benzodiazepin-2-one, C17H15C3N2O Journal of the American Chemical Society. 89: 804-807.  1
1966 Karle IL, Karle J. The crystal structure of the quasi-racemate from (+)-m-methoxyphenoxypropionic acid and (-)-m-bromophenoxypropionic acid Journal of the American Chemical Society. 88: 24-27.  1
1966 Karle IL, Karle J, Britts K. The crystal structures of the isomers trans- and cis-1,2-Dibromo-1,2-dicarbomethoxycyclobutane Journal of the American Chemical Society. 88: 2918-2921.  1
1966 Karle IL, Karle J. On the structutre and stereoconfiguration of panamine, C20H33N3, by X-ray analysis Tetrahedron Letters. 7: 1659-1661.  1
1965 Karle IL, Karle J. The crystal and molecular structure of congressane, C14H20, by X-ray diffraction [5] Journal of the American Chemical Society. 87: 918-920.  1
1965 Moriarty RM, Romain CR, Karle IL, Karle J. The structure of anemonin [7] Journal of the American Chemical Society. 87: 3251-3252.  1
1964 Karle IL, Karle J, Moriarty RM. The structure and stereochemistry of 2-p-methoxyphenyl-3,4-dibenzyl-1,3,4-thiadiazolidine-5-thione by x-ray analysis Tetrahedron Letters. 5: 3579-3582.  1
1964 Karle IL, Karle J, Owen TB, Broge RW, Fox AH, Hoard JL. The configuration of C8F12, a saturated dimer of hexafluorobutadiene [9] Journal of the American Chemical Society. 86: 2523.  1
1963 Karle IL, Karle J. The structure and stereochemistry of Jamine, C21H35N3, by x-ray analysis Tetrahedron Letters. 4: 2065-2067.  1
Show low-probability matches.