John Clark Sheehan - Publications

Affiliations: 
Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
synthesized penicillin from scratch
Website:
http://www.nap.edu/openbook.php?record_id=4990&page=291

79 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2011 Sheehan JC, Corey EJ. The Synthesis of β‐Lactams Organic Reactions. 388-408. DOI: 10.1002/0471264180.Or009.06  0.354
2006 Sheehan JC. Activated Cyclic Derivatives Of Amino Acids In Peptide Synthesis Annals of the New York Academy of Sciences. 88: 665-668. DOI: 10.1111/J.1749-6632.1960.Tb20060.X  0.383
1981 HARA T, SHEEHAN JC. ChemInform Abstract: SYNTHESIS OF 5-ARYL-5,6,7,8-TETRAHYDROTHIAZOLO(3,4-A)PYRIDINIUM BROMIDES Chemischer Informationsdienst. 12. DOI: 10.1002/Chin.198152200  0.386
1980 Sheehan JC, Shibahara S, Chacko E. Simple beta-lactam compounds derived from 6-aminopenicillanic acid. Journal of Medicinal Chemistry. 23: 809-11. PMID 6249932 DOI: 10.1021/Jm00181A020  0.314
1980 SHEEHAN JC, SHIBAHARA S, CHACKO E. ChemInform Abstract: SIMPLE β-LACTAM COMPOUNDS DERIVED FROM 6-AMINOPENICILLANIC ACID Chemischer Informationsdienst. 11. DOI: 10.1002/Chin.198049326  0.327
1978 Sheehan JC, Commons TJ. Reaction of 6(7)-diazopenicillanates and diazocephalosporanates with sulfenyl chlorides. Preparation of 6(7)α-methoxy-substituted thiol penicillanates and thiol cephalosporanates Journal of Organic Chemistry. 43: 2203-2208. DOI: 10.1021/Jo00405A026  0.324
1977 Sheehan JC, Buku A, Chacko E, Commons TJ, Lo YS, Ponzi DR, Schwarzel WC. Derivatives of 6β-methylpenicillanic acid Journal of Organic Chemistry. 42: 4045-4048. DOI: 10.1002/Chin.197816351  0.301
1974 Sheehan JC, Lo YS, Löliger J, Podewell CC. Synthesis of 6-hydroxypenicillanates and 7-hydroxycephalosporanates. The Journal of Organic Chemistry. 39: 1444-5. PMID 4833733 DOI: 10.1021/Jo00926A034  0.375
1974 Sheehan JC, Lo YS. Total synthesis and resolution of terreic acid. Journal of Medicinal Chemistry. 17: 371-2. PMID 4811239 DOI: 10.1002/Chin.197434242  0.353
1974 Sheehan JC, Zoller U. Sulfonation of unsaturated compounds. I. Sulfonation of branched-chain ketones with sulfur trioxide. A one-step synthesis of tetramethylene sulfate through a retro pinacol-type rearrangement Journal of Organic Chemistry. 39: 3415-3416. DOI: 10.1021/Jo00937A025  0.344
1974 Sheehan JC, Zoller U, Ben-Ishai D. α-Halosulfonamides. Synthesis and base-induced reactions Journal of Organic Chemistry. 39: 1817-1819. DOI: 10.1021/Jo00927A006  0.324
1973 Sheehan JC, Guziec FS. Amino group protection in peptide synthesis. The 4,5-diphenyl-4-oxazolin-2-one group. The Journal of Organic Chemistry. 38: 3034-40. PMID 4741306 DOI: 10.1002/Chin.197348462  0.662
1973 Sheehan JC, Ledis SL. Total synthesis of a monocyclic peptide lactone antibiotic, etamycin. Journal of the American Chemical Society. 95: 875-9. PMID 4688657 DOI: 10.1021/Ja00784A041  0.356
1972 Lo YS, Sheehan JC. Synthesis of benzyl 6-oxopenicillanate and derivatives. I. Journal of the American Chemical Society. 94: 8253. PMID 5079968 DOI: 10.1021/Ja00778A064  0.391
1972 Sheehan JC, Guziec FS. 4,5-Diphenyl-4-oxazolin-2-one ring system as an amine protecting group Journal of the American Chemical Society. 94: 6561-6562. DOI: 10.1021/Ja00773A060  0.642
1972 SHEEHAN JC, WILSON RM, OXFORD AW. ChemInform Abstract: PHOTOLYSE VON METHOXYSUBSTITUIERTEN BENZOINESTERN, EINE LICHTEMPFINDLICHE SCHUTZGRUPPE FUER CARBONSAEUREN Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/Chin.197211149  0.307
1971 Sheehan JC, Wilson RM, Oxford AW. The photolysis of methoxy-substituted benzoin esters. A photosensitive protecting group for carboxylic acids Journal of the American Chemical Society. 93: 7222-7228. DOI: 10.1021/Ja00755A017  0.431
1969 Wilson RM, Sheehan JC. The acid-catalyzed solvolysis of benzoin tosylate in aromatic solvents Journal of the American Chemical Society. 91: 7378-7380. DOI: 10.1021/Ja01054A027  0.404
1969 Marschner RF, Riegel B, Mosher WA, Hanford WE, Sheehan JC, Cooke LM, Overberger CG, Leermakers JA, Lyman AL, Henze RE, Long FA, Craig PN, Newman P, Stewart J, Bailey WJ, et al. American Chemical Society official reports: 157th national meeting Minneapolis, April 13-18, 1969 Chemical and Engineering News. 47: 50-56.  0.329
1968 Sheehan JC, Dadiac M. The synthesis of oxygen analogs of cepham. A new bicyclic system Journal of Heterocyclic Chemistry. 5: 779-783. DOI: 10.1002/Jhet.5570050607  0.355
1967 Sheehan JC. The chemistry of synthetic and semisynthetic penicillins. Annals of the New York Academy of Sciences. 145: 216-23. PMID 4935171 DOI: 10.1111/J.1749-6632.1967.Tb50220.X  0.321
1967 Sheehan JC, Wilson RM. The stereospecific synthesis and electronic absorption properties of cis- and trans-4-acetoxyisopulegone Journal of the American Chemical Society. 89: 3457-3462. DOI: 10.1021/Ja00990A018  0.347
1965 SHEEHAN JC, PRESTON J, CRUICKSHANK PA. A RAPID SYNTHESIS OF OLIGOPEPTIDE DERIVATIVES WITHOUT ISOLATION OF INTERMEDIATES. Journal of the American Chemical Society. 87: 2492-3. PMID 14327157 DOI: 10.1021/Ja01089A034  0.364
1965 Sheehan JC, Brandt KG. A novel cleavage of the penicillin nucleus. Journal of the American Chemical Society. 87: 5468-9. PMID 5844823 DOI: 10.1021/Ja00951A038  0.705
1964 Sheehan JC, Wilson RM. Photolysis of desyl compounds. A new photolytic cyclization Journal of the American Chemical Society. 86: 5277-5281. DOI: 10.1021/Ja01077A046  0.373
1964 Sheehan JC, Lengyel I. The synthesis and reactions of an α-lactam, 1-t-butyl-3,3-dimethylaziridinone Journal of the American Chemical Society. 86: 1356-1359. DOI: 10.1021/Ja01061A018  0.315
1963 Sheehan JC, Howell MG. The synthesis and resolution of methylleucines Journal of Organic Chemistry. 28: 2279-2282. DOI: 10.1021/Jo01044A030  0.335
1963 Sheehan JC, Whitney JG. The synthesis of cis- and trans-3-hydroxy-L-proline, two new amino acids from the antibiotic telomycin Journal of the American Chemical Society. 85: 3863-3865. DOI: 10.1021/Ja00906A027  0.331
1962 Sheehan JC, Grenda VJ. The N-(2-hydroxyarylidene) protecting group in peptide synthesis Journal of the American Chemical Society. 84: 2417-2420. DOI: 10.1021/Ja00871A029  0.344
1962 Sheehan JC, Maeda K, Sen AK, Stock JA. The isolation, characterization and synthesis of erythro-β-hydroxy-L-leucine, a new amino acid from the antibiotic telomycin Journal of the American Chemical Society. 84: 1303-1305. DOI: 10.1021/Ja00866A048  0.343
1961 Djerassi C, Lund E, Bunnenberg E, Sheehan JC. Optical rotatory dispersion studies. LI. Absolute configurational assignments of α-amino acids and peptides through anomalous rotatory dispersion of N-phthaloyl derivatives Journal of Organic Chemistry. 26: 4509-4511. DOI: 10.1021/Jo01069A073  0.34
1961 Sheehan JC, Chandler RE. A sterically controlled synthesis of amino acids Journal of the American Chemical Society. 83: 4795-4797. DOI: 10.1021/Ja01484A024  0.342
1961 Cruickshank PA, Sheehan JC. Intramolecular assistance of decarboxylative acylation Journal of the American Chemical Society. 83: 2891-2895. DOI: 10.1021/Ja01474A024  0.32
1959 Sheehan JC, Hasspacher K, Yeh YL. Activated cyclic derivatives of amino acids [6] Journal of the American Chemical Society. 81: 6086. DOI: 10.1021/Ja01531A062  0.315
1959 Sheehan JC, Logan KRH. A General Synthesis Of The Penicillins Journal of the American Chemical Society. 81: 5838-5839. DOI: 10.1021/Ja01530A079  0.344
1958 Sheehan J, Hlavka J. Notes - A Reaction Peptide Intermediate Derived from Ethoxyacetylene The Journal of Organic Chemistry. 23: 635-636. DOI: 10.1021/Jo01098A621  0.328
1958 Sheehan JC, Zachau HG, Lawson WB. The structure of etamycin Journal of the American Chemical Society. 80: 3349-3355. DOI: 10.1021/Ja01546A039  0.461
1958 Sheehan JC, Yang DDH. A new synthesis of cysteinyl peptides Journal of the American Chemical Society. 80: 1158-1164. DOI: 10.1021/Ja01538A037  0.353
1958 Sheehan JC, Yang DDH. The use of N-formylamino acids in peptide synthesis Journal of the American Chemical Society. 80: 1154-1158. DOI: 10.1021/Ja01538A036  0.359
1957 Sheehan JC. The synthesis of substituted penicillins and simpler structural analogs. XII. 6-benzylsulfonamidopenicillanic acid Journal of the American Chemical Society. 79: 237-240. DOI: 10.1021/Ja01558A062  0.389
1956 Sheehan JC, Hlavka JJ. The use of water-soluble and basic carbodiimides in peptide synthesis Journal of Organic Chemistry. 21: 439-441. DOI: 10.1021/Jo01110A017  0.311
1956 Sheehan JC, Cruickshank PA. The synthesis of substituted penicillins and simpler structural analogs. XI. Methyl 6-benzylsulfonamidopenicillanate Journal of the American Chemical Society. 78: 3683-3686. DOI: 10.1021/Ja01596A034  0.352
1956 Sheehan JC, Cruickshank PA. The synthesis of substituted penicillins and simpler structural analogs. X. The cyclization of 4-carbomethoxy-5,5-dimethyl-α-phthalimido-2-thiazolidineacetic acid to methyl 6-phthalimidopenicillanate Journal of the American Chemical Society. 78: 3680-3683. DOI: 10.1021/Ja01596A033  0.373
1956 Sheehan JC, Cruickshank PA. The synthesis of substituted penicillins and simpler structural analogs. IX. 4-Carboxy-5,5-dimethyl-α-phthalimido-2-thiazolidineacetic acid derivatives Journal of the American Chemical Society. 78: 3677-3680. DOI: 10.1021/Ja01596A032  0.396
1956 Sheehan JC, Goodman M, Hess GP. Peptide derivatives containing hydroxyamino acids Journal of the American Chemical Society. 78: 1367-1369. DOI: 10.1021/Ja01588A029  0.693
1955 Sheehan JC, Goodman M, Richardson WL. The product derived from the cyclization of tri-glycine azide Journal of the American Chemical Society. 77: 6391. DOI: 10.1021/Ja01628A107  0.459
1955 Sheehan JC, Hess GP. A New Method of Forming Peptide Bonds Journal of the American Chemical Society. 77: 1067-1068. DOI: 10.1021/Ja01609A099  0.634
1954 Sheehan JC, Bissell ER. The synthesis of dihydrometeloidine and related compounds Journal of Organic Chemistry. 19: 270-276. DOI: 10.1021/Jo01367A014  0.312
1954 Sheehan JC, Richardson WL. A new method for the synthesis of macrocyclic peptides Journal of the American Chemical Society. 76: 6329-6330. DOI: 10.1021/Ja01653A026  0.352
1954 Sheehan JC, Johnson DA. The synthesis of substituted penicillins and simpler structural analogs. VIII. Phthalimidomalonaldehydic esters: Synthesis and condensation with penicillamine Journal of the American Chemical Society. 76: 158-160. DOI: 10.1021/Ja01630A043  0.406
1953 Sheehan JC, Coderre RC. The formation of five- and six-membered rings by the acyloin condensation. III. Cyclization of diethyl 2-carboxy-2-methylcyclohexane-1-acetate Journal of the American Chemical Society. 75: 3997-3999. DOI: 10.1021/Ja01112A035  0.325
1953 Sheehan JC, Henery-Logan KR, Johnson DA. The synthesis of substituted penicillins and simpler structural analogs. VII. The cyclization of a penicilloate derivative to methyl phthalimidopenicillanate [12] Journal of the American Chemical Society. 75: 3292-3293. DOI: 10.1021/Ja01109A526  0.374
1952 Sheehan JC, Bose AK. Attempted cyclization of N-chloroacetylthiazolidines Journal of the American Chemical Society. 74: 4957-4958. DOI: 10.1021/Ja01139A516  0.463
1952 Sheehan JC, Johnson DA. The synthesis and reactions of N-acyl thiol amino acids [2] Journal of the American Chemical Society. 74: 4726-4727. DOI: 10.1021/Ja01138A528  0.362
1952 Sheehan JC, Corey EJ. Syntheses and reactions of acyclic N,N-diacylglycines Journal of the American Chemical Society. 74: 4555-4559. DOI: 10.1021/Ja01138A030  0.389
1952 Sheehan JC, Bloom BM. The synthesis of teloidinone and 6-hydroxytropinone Journal of the American Chemical Society. 74: 3825-3828. DOI: 10.1021/Ja01135A032  0.375
1952 Sheehan JC, Chapman DW, Roth RW. The synthesis of stereochemically pure peptide derivatives by the phthaloyl method Journal of the American Chemical Society. 74: 3822-3825. DOI: 10.1021/Ja01135A031  0.362
1952 Sheehan JC, Corey EJ. The condensation products of oxalyl chloride with monosubstituted amides: Structure and reactions Journal of the American Chemical Society. 74: 360-365. DOI: 10.1021/Ja01122A021  0.418
1952 Sheehan JC, Whitney JG. The isolation, characterization and synthesis of 3-hydroxyprolines [17] Journal of the American Chemical Society. 84: 3980. DOI: 10.1021/Ja00879A048  0.32
1951 Sheehan JC, Corey EJ. The synthesis of substituted penicillins and simpler structural analogs. VI. The synthesis of a 6-phenylacetylamino-β-lactam-thiazolidine Journal of the American Chemical Society. 73: 4756-4759. DOI: 10.1021/Ja01154A082  0.497
1951 Sheehan JC, Laubach GD. The synthesis of substituted penicillins and simpler structural analogs. V. The application of 5-phenyloxazolidine-2,4-diones to the synthesis of phenylacetylamino-β-lactams Journal of the American Chemical Society. 73: 4752-4755. DOI: 10.1021/Ja01154A081  0.368
1951 Sheehan JC, Laubach GD. The synthesis of substituted penicillins and simpler structural analogs. IV. The synthesis of a 5-phenyl penicillin and α-succinimido β-lactam-thiazolidines Journal of the American Chemical Society. 73: 4376-4380. DOI: 10.1021/Ja01153A100  0.375
1951 Sheehan JC, Hill HW, Buhle EL. The synthesis of substituted penicillins and simpler structural analogs. III. Phthalimido β-lactam-thiazolidines derived from penicillamine Journal of the American Chemical Society. 73: 4373-4375. DOI: 10.1021/Ja01153A099  0.367
1951 Sheehan JC, Ryan JJ. The synthesis of substituted penicillins and simpler structural analogs. II. α-Acylamino β-lactam-thiazolidines Journal of the American Chemical Society. 73: 4367-4372. DOI: 10.1021/Ja01153A098  0.333
1951 Sheehan JC, Bose AK. The synthesis and reactions of some substituted β-lactams Journal of the American Chemical Society. 73: 1761-1765. DOI: 10.1021/Ja01148A095  0.54
1951 Sheehan JC, Robinson CA. The synthesis of phenyl-substituted triazole analogs of histamine Journal of the American Chemical Society. 73: 1207-1210. DOI: 10.1021/Ja01147A098  0.401
1951 Sheehan JC, Ryan JJ. The synthesis of substituted penicillins and simpler structural analogs. I. Alpha amino monocyclic β-lactams Journal of the American Chemical Society. 73: 1204-1206. DOI: 10.1021/Ja01147A097  0.346
1950 Sheehan JC, Bose AK. A new synthesis of β-lactams Journal of the American Chemical Society. 72: 5158-5161. DOI: 10.1021/Ja01167A099  0.524
1950 Sheehan JC, Buhle EL, Corey EJ, Laubach GD, Ryan JJ. The total synthesis of a 5-phenyl penicillin: Methyl 5-phenyl-(2-carbomethoxyethyl)-penicillinate [7] Journal of the American Chemical Society. 72: 3828-3829. DOI: 10.1021/Ja01164A534  0.461
1950 Sheehan JC, O'Neill RC, White MA. The formation of five and six-membered rings by the acyloin condensation. I. The cyclization of glutaric and adipic esters Journal of the American Chemical Society. 72: 3376-3378. DOI: 10.1021/Ja01164A016  0.344
1950 Sheehan JC, Duggins WE. The rearrangement of substituted acyl amino acids to unsaturated azlactones Journal of the American Chemical Society. 72: 2475-2477. DOI: 10.1021/Ja01162A033  0.341
1950 Sheehan JC, Bolhofer WA. The synthesis of hydroxylysine Journal of the American Chemical Society. 72: 2472-2474. DOI: 10.1021/Ja01162A032  0.375
1950 Sheehan JC. Peptide syntheses using energy-rich phosphorylated amino acid derivatives Journal of the American Chemical Society. 72: 1312-1316. DOI: 10.1021/Ja01159A066  0.332
1949 SHEEHAN JC, ROBINSON CA. The synthesis of triazole analogs of histamine and related compounds. Journal of the American Chemical Society. 71: 1436-40. PMID 18128366 DOI: 10.1021/Ja01172A083  0.317
1949 Sheehan JC, Frank VS. A new synthetic route to peptides Journal of the American Chemical Society. 71: 1856-1861. DOI: 10.1021/Ja01173A095  0.316
1949 Bachmann WE, Sheehan JC. A new method of preparing the high explosive RDX Journal of the American Chemical Society. 71: 1842-1845. DOI: 10.1021/Ja01173A092  0.519
1941 Bachmann WE, Sheehan JC. The synthesis of 1-methyl-, 1-ethyl-, and 3-ethyl-4,5-methylenephenanthrene Journal of the American Chemical Society. 63: 2598-2600. DOI: 10.1021/Ja01855A017  0.568
1941 Bachmann WE, Sheehan JC. The synthesis of 4,5-methylenephenanthrene Journal of the American Chemical Society. 13: 204-206. DOI: 10.1021/Ja01846A046  0.598
1940 Bachmann WE, Sheehan JC. The synthesis of 2-, 4- and 9-fluoreneacetic acid Journal of the American Chemical Society. 62: 2687-2690. DOI: 10.1021/Ja01867A025  0.593
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