Stephen James Lippard - Publications

Affiliations: 
1966-1983 Columbia University, New York, NY 
 1983- Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
bioinorganic chemistry
Website:
http://lippardlab.mit.edu/stephen-j-lippard

351 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Barandov A, Bartelle BB, Williamson CG, Loucks ES, Lippard SJ, Jasanoff A. Sensing intracellular calcium ions using a manganese-based MRI contrast agent. Nature Communications. 10: 897. PMID 30796208 DOI: 10.1038/s41467-019-08558-7  0.56
2019 Almaqwashi AA, Zhou W, Naufer MN, Riddell IA, Yilmaz ÖH, Lippard SJ, Williams MC. DNA intercalation facilitates efficient DNA-targeted covalent binding of phenanthriplatin. Journal of the American Chemical Society. PMID 30599508 DOI: 10.1021/jacs.8b10252  0.6
2018 Richardson CER, Nolan EM, Shoulders MD, Lippard SJ. A sensitive, non-radioactive assay for Zn(II) uptake into metazoan cells. Biochemistry. PMID 30381945 DOI: 10.1021/acs.biochem.8b01043  1
2018 Han Y, Goldberg JM, Lippard SJ, Palmer AE. Superiority of SpiroZin2 Versus FluoZin-3 for monitoring vesicular Zn allows tracking of lysosomal Zn pools. Scientific Reports. 8: 15034. PMID 30302024 DOI: 10.1038/s41598-018-33102-w  1
2018 Lin X, Chen X, Riddell IA, Tao W, Wang J, Hollett G, Lippard SJ, Farokhzad OC, Shi J, Wu J. Glutathione-scavenging Poly(disulfide amide) Nanoparticles for Effective Delivery of Pt(IV) Prodrugs and Reversal of Cisplatin Resistance. Nano Letters. PMID 29902013 DOI: 10.1021/acs.nanolett.8b01924  0.6
2018 Hucke A, Park GY, Bauer OB, Beyer G, Köppen C, Zeeh D, Wehe CA, Sperling M, Schröter R, Kantauskaitè M, Hagos Y, Karst U, Lippard SJ, Ciarimboli G. Interaction of the New Monofunctional Anticancer Agent Phenanthriplatin With Transporters for Organic Cations. Frontiers in Chemistry. 6: 180. PMID 29888219 DOI: 10.3389/fchem.2018.00180  0.8
2018 Goldberg JM, Lippard SJ. New Tools Uncover New Functions for Mobile Zinc in the Brain. Biochemistry. PMID 29553247 DOI: 10.1021/acs.biochem.8b00108  1
2018 Zhou W, Almeqdadi M, Xifaras ME, Riddell IA, Yilmaz ÖH, Lippard SJ. The effect of geometric isomerism on the anticancer activity of the monofunctional platinum complex trans-[Pt(NH)(phenanthridine)Cl]NO. Chemical Communications (Cambridge, England). PMID 29484327 DOI: 10.1039/c8cc00393a  0.6
2018 Goldberg JM, Wang F, Sessler CD, Vogler NW, Zhang DY, Loucks WH, Tzounopoulos T, Lippard SJ. Photoactivatable Sensors for Detecting Mobile Zinc. Journal of the American Chemical Society. PMID 29384658 DOI: 10.1021/jacs.7b12766  1
2018 Richardson CER, Cunden LS, Butty VL, Nolan EM, Lippard SJ, Shoulders MD. A Method for Selective Depletion of Zn(II) Ions from Complex Biological Media and Evaluation of Cellular Consequences of Zn(II) Deficiency. Journal of the American Chemical Society. PMID 29334734 DOI: 10.1021/jacs.7b12897  1
2017 Goldberg JM, Lippard SJ. Challenges and Opportunities in Brain Bioinorganic Chemistry. Accounts of Chemical Research. 50: 577-579. PMID 28945403 DOI: 10.1021/acs.accounts.6b00561  1
2017 Sessler CD, Rahm M, Becker S, Goldberg JM, Wang F, Lippard SJ. CF2H, a Hydrogen Bond Donor. Journal of the American Chemical Society. PMID 28576078 DOI: 10.1021/jacs.7b04457  1
2017 Bruno PM, Liu Y, Park GY, Murai J, Koch CE, Eisen TJ, Pritchard JR, Pommier Y, Lippard SJ, Hemann MT. A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress. Nature Medicine. PMID 28263311 DOI: 10.1038/nm.4291  1
2017 Awuah SG, Riddell IA, Lippard SJ. Repair shielding of platinum-DNA lesions in testicular germ cell tumors by high-mobility group box protein 4 imparts cisplatin hypersensitivity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28096358 DOI: 10.1073/pnas.1615327114  1
2017 Li Y, Andereggen L, Yuki K, Omura K, Yin Y, Gilbert HY, Erdogan B, Asdourian MS, Shrock C, de Lima S, Apfel UP, Zhuo Y, Hershfinkel M, Lippard SJ, Rosenberg PA, et al. Mobile zinc increases rapidly in the retina after optic nerve injury and regulates ganglion cell survival and optic nerve regeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 28049831 DOI: 10.1073/pnas.1616811114  0.68
2016 Goldberg JM, Loas A, Lippard SJ. Metalloneurochemistry and the Pierian Spring: 'Shallow Draughts Intoxicate the Brain'. Israel Journal of Chemistry. 56: 791-802. PMID 28190893 DOI: 10.1002/ijch.201600034  1
2016 Zheng YR, Suntharalingam K, Bruno PM, Lin W, Wang W, Hemann MT, Lippard SJ. Mechanistic Studies of the Anticancer Activity of An Octahedral Hexanuclear Pt(II) Cage. Inorganica Chimica Acta. 452: 125-129. PMID 27818526 DOI: 10.1016/j.ica.2016.03.021  1
2016 Riddell IA, Agama K, Park GY, Pommier Y, Lippard SJ. Phenanthriplatin Acts as a Covalent Poison of Topoisomerase II Cleavage Complexes. Acs Chemical Biology. PMID 27648475 DOI: 10.1021/acschembio.6b00565  0.8
2016 Patra M, Awuah SG, Lippard SJ. Chemical approach to positional isomers of glucose-platinum conjugates reveals specific cancer targeting through glucose-transporter mediated uptake in vitro and in vivo. Journal of the American Chemical Society. PMID 27570149 DOI: 10.1021/jacs.6b06937  1
2016 Riddell IA, Johnstone TC, Park GY, Lippard SJ. Nucleotide Binding Preference of the Monofunctional Platinum Anticancer-Agent Phenanthriplatin. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27111128 DOI: 10.1002/chem.201600236  1
2016 Barandov A, Bartelle BB, Gonzalez BA, White WL, Lippard SJ, Jasanoff A. Membrane-permeable Mn(III) complexes for molecular MRI of intracellular targets. Journal of the American Chemical Society. PMID 27088782 DOI: 10.1021/jacs.5b13337  0.56
2016 Czapar AE, Zheng YR, Riddell IA, Shukla S, Awuah SG, Lippard SJ, Steinmetz NF. Tobacco mosaic virus delivery of phenanthriplatin for cancer therapy. Acs Nano. PMID 26982250 DOI: 10.1021/acsnano.5b07360  1
2016 Kim S, Minier MA, Loas A, Becker S, Wang F, Lippard SJ. Addition to "Achieving Reversible Sensing of Nitroxyl by Tuning the Ligand Environment of Azamacrocyclic Copper(II) Complexes". Journal of the American Chemical Society. PMID 26977776 DOI: 10.1021/jacs.6b01932  1
2016 Awuah SG, Zheng YR, Bruno PM, Hemann MT, Lippard SJ. Correction to "A Pt(IV) Pro-drug Preferentially Targets Indoleamine-2,3-dioxygenase, Providing Enhanced Ovarian Cancer Immuno-Chemotherapy". Journal of the American Chemical Society. PMID 26916820 DOI: 10.1021/jacs.6b01316  1
2016 Zastrow ML, Radford RJ, Chyan W, Anderson CT, Zhang DY, Loas A, Tzounopoulos T, Lippard SJ. Reaction-Based Probes for Imaging Mobile Zinc in Live Cells and Tissues. Acs Sensors. 1: 32-39. PMID 26878065 DOI: 10.1021/acssensors.5b00022  1
2016 Johnstone TC, Suntharalingam K, Lippard SJ. The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs. Chemical Reviews. PMID 26865551 DOI: 10.1021/acs.chemrev.5b00597  1
2016 Kim S, Minier MA, Loas A, Becker S, Wang F, Lippard SJ. Achieving Reversible Sensing of Nitroxyl (HNO) by Tuning the Ligand Environment of Azamacrocyclic Copper(II) Com-plexes. Journal of the American Chemical Society. PMID 26836121 DOI: 10.1021/jacs.5b12825  1
2016 Patra M, Johnstone TC, Suntharalingam K, Lippard SJ. A Potent Glucose-Platinum Conjugate Exploits Glucose Transporters and Preferentially Accumulates in Cancer Cells. Angewandte Chemie (International Ed. in English). PMID 26749149 DOI: 10.1002/anie.201510551  1
2015 Loas A, Radford RJ, Deliz Liang A, Lippard SJ. Solid-phase synthesis provides a modular, lysine-based platform for fluorescent discrimination of nitroxyl and biological thiols. Chemical Science. 6: 4131-4140. PMID 28717469 DOI: 10.1039/c5sc00880h  1
2015 Kalappa BI, Anderson CT, Goldberg JM, Lippard SJ, Tzounopoulos T. AMPA receptor inhibition by synaptically released zinc. Proceedings of the National Academy of Sciences of the United States of America. PMID 26647187 DOI: 10.1073/pnas.1512296112  1
2015 Awuah SG, Zheng YR, Bruno PM, Hemann MT, Lippard SJ. A Platinum(IV) Pro-drug Preferentially Targets IDO Providing Enhanced Ovarian Cancer Immuno-Chemotherapy. Journal of the American Chemical Society. PMID 26561720 DOI: 10.1021/jacs.5b10182  1
2015 Rivera-Fuentes P, Lippard SJ. Metal-Based Optical Probes for Live Cell Imaging of Nitroxyl (HNO). Accounts of Chemical Research. PMID 26550842 DOI: 10.1021/acs.accounts.5b00388  1
2015 Miller MA, Zheng YR, Gadde S, Pfirschke C, Zope H, Engblom C, Kohler RH, Iwamoto Y, Yang KS, Askevold B, Kolishetti N, Pittet M, Lippard SJ, Farokhzad OC, Weissleder R. Tumour-associated macrophages act as a slow-release reservoir of nano-therapeutic Pt(IV) pro-drug. Nature Communications. 6: 8692. PMID 26503691 DOI: 10.1038/ncomms9692  1
2015 Karlin KD, Lippard SJ, Valentine JS, Burrows CJ. Solving 21st Century Problems in Biological Inorganic Chemistry Using Synthetic Models. Accounts of Chemical Research. 48: 2659-60. PMID 26481328 DOI: 10.1021/acs.accounts.5b00447  1
2015 Minier MA, Lippard SJ. (19)F NMR study of ligand dynamics in carboxylate-bridged diiron(ii) complexes supported by a macrocyclic ligand. Dalton Transactions (Cambridge, England : 2003). 44: 18111-21. PMID 26418547 DOI: 10.1039/c5dt02138c  1
2015 Wang W, Liang AD, Lippard SJ. Coupling Oxygen Consumption with Hydrocarbon Oxidation in Bacterial Multicomponent Monooxygenases. Accounts of Chemical Research. PMID 26293615 DOI: 10.1021/acs.accounts.5b00312  1
2015 Liang AD, Lippard SJ. Single Turnover Reveals Oxygenated Intermediates in Toluene/o-Xylene Monooxygenase in the Presence of the Native Redox Partners. Journal of the American Chemical Society. PMID 26267757 DOI: 10.1021/jacs.5b07055  1
2015 Hopmann KH, Conradie J, Tangen E, Tonzetich ZJ, Lippard SJ, Ghosh A. Singlet-Triplet Gaps of Cobalt Nitrosyls: Insights from Tropocoronand Complexes. Inorganic Chemistry. 54: 7362-7. PMID 26203786 DOI: 10.1021/acs.inorgchem.5b00901  1
2015 Anderson CT, Radford RJ, Zastrow ML, Zhang DY, Apfel UP, Lippard SJ, Tzounopoulos T. Modulation of extrasynaptic NMDA receptors by synaptic and tonic zinc. Proceedings of the National Academy of Sciences of the United States of America. 112: E2705-14. PMID 25947151 DOI: 10.1073/pnas.1503348112  1
2015 Rivera-Fuentes P, Wrobel AT, Zastrow ML, Khan M, Georgiou J, Luyben TT, Roder JC, Okamoto K, Lippard SJ. A Far-Red Emitting Probe for Unambiguous Detection of Mobile Zinc in Acidic Vesicles and Deep Tissue. Chemical Science (Royal Society of Chemistry : 2010). 6: 1944-1948. PMID 25815162 DOI: 10.1039/C4SC03388D  1
2015 Perez-Rosello T, Anderson CT, Ling C, Lippard SJ, Tzounopoulos T. Tonic zinc inhibits spontaneous firing in dorsal cochlear nucleus principal neurons by enhancing glycinergic neurotransmission. Neurobiology of Disease. PMID 25796568 DOI: 10.1016/j.nbd.2015.03.012  1
2015 Sazinsky MH, Lippard SJ. Methane monooxygenase: functionalizing methane at iron and copper. Metal Ions in Life Sciences. 15: 205-56. PMID 25707469 DOI: 10.1007/978-3-319-12415-5_6  1
2015 Suntharalingam K, Awuah SG, Bruno PM, Johnstone TC, Wang F, Lin W, Zheng YR, Page JE, Hemann MT, Lippard SJ. Necroptosis-inducing rhenium(V) oxo complexes. Journal of the American Chemical Society. 137: 2967-74. PMID 25698398 DOI: 10.1021/ja511978y  1
2015 Johnstone TC, Suntharalingam K, Lippard SJ. Third row transition metals for the treatment of cancer. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 373. PMID 25666060 DOI: 10.1098/rsta.2014.0185  1
2015 Zheng YR, Suntharalingam K, Johnstone TC, Lippard SJ. Encapsulation of Pt(IV) Prodrugs within a Pt(II) Cage for Drug Delivery. Chemical Science (Royal Society of Chemistry : 2010). 6: 1189-1193. PMID 25621144 DOI: 10.1039/C4SC01892C  1
2015 Kozhukh J, Minier MA, Lippard SJ. Synthesis and characterization of mononuclear, pseudotetrahedral cobalt(III) compounds. Inorganic Chemistry. 54: 418-24. PMID 25531129 DOI: 10.1021/ic5009279  1
2015 Johnstone TC, Lippard SJ. Improvements in the Synthesis and Understanding of the Iodo-bridged Intermediate en Route to the Pt(IV) Prodrug Satraplatin. Inorganica Chimica Acta. 424: 254-259. PMID 25435590 DOI: 10.1016/j.ica.2014.08.047  1
2015 Zhang DY, Azrad M, Demark-Wahnefried W, Frederickson CJ, Lippard SJ, Radford RJ. Peptide-based, two-fluorophore, ratiometric probe for quantifying mobile zinc in biological solutions. Acs Chemical Biology. 10: 385-9. PMID 25382858 DOI: 10.1021/cb500617c  1
2015 Johnstone TC, Alexander SM, Wilson JJ, Lippard SJ. Oxidative halogenation of cisplatin and carboplatin: synthesis, spectroscopy, and crystal and molecular structures of Pt(IV) prodrugs. Dalton Transactions (Cambridge, England : 2003). 44: 119-29. PMID 25367395 DOI: 10.1039/c4dt02627f  1
2015 Loas A, Radford RJ, Deliz Liang A, Lippard SJ. Solid-phase synthesis provides a modular, lysine-based platform for fluorescent discrimination of nitroxyl and biological thiols Chemical Science. 6: 4131-4140. DOI: 10.1039/c5sc00880h  1
2014 Radford RJ, Chyan W, Lippard SJ. Peptide Targeting of Fluorescein-Based Sensors to Discrete Intracellular Locales. Chemical Science (Royal Society of Chemistry : 2010). 5: 4512-4516. PMID 25512838 DOI: 10.1039/C4SC01280A  1
2014 Victor E, Kim S, Lippard SJ. Synthesis of bis(imidazole) metal complexes and their use in rapid NO detection and quantification devices. Inorganic Chemistry. 53: 12809-21. PMID 25419858 DOI: 10.1021/ic501765g  1
2014 Liang AD, Lippard SJ. Component interactions and electron transfer in toluene/o-xylene monooxygenase. Biochemistry. 53: 7368-75. PMID 25402597 DOI: 10.1021/bi500892n  1
2014 Suntharalingam K, Lin W, Johnstone TC, Bruno PM, Zheng YR, Hemann MT, Lippard SJ. A breast cancer stem cell-selective, mammospheres-potent osmium(VI) nitrido complex. Journal of the American Chemical Society. 136: 14413-6. PMID 25247635 DOI: 10.1021/ja508808v  1
2014 Jiang Y, Hayashi T, Matsumura H, Do LH, Majumdar A, Lippard SJ, Moënne-Loccoz P. Light-induced N₂O production from a non-heme iron-nitrosyl dimer. Journal of the American Chemical Society. 136: 12524-7. PMID 25158917 DOI: 10.1021/ja504343t  1
2014 Wang W, Iacob RE, Luoh RP, Engen JR, Lippard SJ. Electron transfer control in soluble methane monooxygenase. Journal of the American Chemical Society. 136: 9754-62. PMID 24937475 DOI: 10.1021/ja504688z  1
2014 Gregory MT, Park GY, Johnstone TC, Lee YS, Yang W, Lippard SJ. Structural and mechanistic studies of polymerase η bypass of phenanthriplatin DNA damage. Proceedings of the National Academy of Sciences of the United States of America. 111: 9133-8. PMID 24927576 DOI: 10.1073/pnas.1405739111  1
2014 Loas A, Radford RJ, Lippard SJ. Addition of a second binding site increases the dynamic range but alters the cellular localization of a red fluorescent probe for mobile zinc. Inorganic Chemistry. 53: 6491-3. PMID 24915285 DOI: 10.1021/ic500732z  1
2014 Zheng YR, Suntharalingam K, Johnstone TC, Yoo H, Lin W, Brooks JG, Lippard SJ. Pt(IV) prodrugs designed to bind non-covalently to human serum albumin for drug delivery. Journal of the American Chemical Society. 136: 8790-8. PMID 24902769 DOI: 10.1021/ja5038269  1
2014 Liang AD, Wrobel AT, Lippard SJ. A flexible glutamine regulates the catalytic activity of toluene o-xylene monooxygenase. Biochemistry. 53: 3585-92. PMID 24873259 DOI: 10.1021/bi500387y  1
2014 Victor E, Lippard SJ. A tetranitrosyl [4Fe-4S] cluster forms en route to Roussin's black anion: nitric oxide reactivity of [Fe4S4(LS3)L'](2-). Inorganic Chemistry. 53: 5311-20. PMID 24773390 DOI: 10.1021/ic500586g  1
2014 Minier MA, Lippard SJ. Conversion Between Doubly and Triply Carboxylate-Bridged Di(ethylzinc) Complexes and Formation of the (μ-Oxo)tetrazinc Carboxylate [Zn4O(Ar(Tol)CO2)6]. Organometallics. 33: 1462-1466. PMID 24761049 DOI: 10.1021/om5000503  1
2014 Khan M, Goldsmith CR, Huang Z, Georgiou J, Luyben TT, Roder JC, Lippard SJ, Okamoto K. Two-photon imaging of Zn2+ dynamics in mossy fiber boutons of adult hippocampal slices. Proceedings of the National Academy of Sciences of the United States of America. 111: 6786-91. PMID 24757053 DOI: 10.1073/pnas.1405154111  1
2014 Rivera-Fuentes P, Lippard SJ. SpiroZin1: a reversible and pH-Insensitive, reaction-based, red-fluorescent probe for imaging biological mobile zinc. Chemmedchem. 9: 1238-43. PMID 24616292 DOI: 10.1002/cmdc.201400014  1
2014 Wrobel AT, Johnstone TC, Deliz Liang A, Lippard SJ, Rivera-Fuentes P. A fast and selective near-infrared fluorescent sensor for multicolor imaging of biological nitroxyl (HNO). Journal of the American Chemical Society. 136: 4697-705. PMID 24564324 DOI: 10.1021/ja500315x  1
2014 Johnstone TC, Lippard SJ. Reinterpretation of the vibrational spectroscopy of the medicinal bioinorganic synthon c,c,t-[Pt(NH3)2Cl2(OH)2]. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 19: 667-74. PMID 24515615 DOI: 10.1007/s00775-014-1109-6  1
2014 Suntharalingam K, Wilson JJ, Lin W, Lippard SJ. A dual-targeting, p53-independent, apoptosis-inducing platinum(II) anticancer complex, [Pt(BDI(QQ))]Cl. Metallomics : Integrated Biometal Science. 6: 437-43. PMID 24514456 DOI: 10.1039/c3mt00364g  1
2014 Wang W, Lippard SJ. Diiron oxidation state control of substrate access to the active site of soluble methane monooxygenase mediated by the regulatory component. Journal of the American Chemical Society. 136: 2244-7. PMID 24476336 DOI: 10.1021/ja412351b  1
2014 Suntharalingam K, Song Y, Lippard SJ. Conjugation of vitamin E analog α-TOS to Pt(IV) complexes for dual-targeting anticancer therapy. Chemical Communications (Cambridge, England). 50: 2465-8. PMID 24452361 DOI: 10.1039/c3cc48740g  1
2014 Johnstone TC, Lippard SJ. The chiral potential of phenanthriplatin and its influence on guanine binding. Journal of the American Chemical Society. 136: 2126-34. PMID 24417436 DOI: 10.1021/ja4125115  1
2014 Johnstone TC, Park GY, Lippard SJ. Understanding and improving platinum anticancer drugs--phenanthriplatin. Anticancer Research. 34: 471-6. PMID 24403503  1
2014 Johnstone TC, Alexander SM, Lin W, Lippard SJ. Effects of monofunctional platinum agents on bacterial growth: a retrospective study. Journal of the American Chemical Society. 136: 116-8. PMID 24364388 DOI: 10.1021/ja411742c  1
2014 Majumdar A, Apfel UP, Jiang Y, Moënne-Loccoz P, Lippard SJ. Versatile reactivity of a solvent-coordinated diiron(II) compound: synthesis and dioxygen reactivity of a mixed-valent Fe(II)Fe(III) species. Inorganic Chemistry. 53: 167-81. PMID 24359397 DOI: 10.1021/ic4019585  1
2014 Chyan W, Zhang DY, Lippard SJ, Radford RJ. Reaction-based fluorescent sensor for investigating mobile Zn2+ in mitochondria of healthy versus cancerous prostate cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 143-8. PMID 24335702 DOI: 10.1073/pnas.1310583110  1
2014 Wilson JJ, Lippard SJ. Synthetic methods for the preparation of platinum anticancer complexes. Chemical Reviews. 114: 4470-95. PMID 24283498 DOI: 10.1021/cr4004314  1
2014 Victor E, Minier MA, Lippard SJ. Synthesis and characterization of a linear dinitrosyl-triiron complex European Journal of Inorganic Chemistry. 2014: 5640-5645. DOI: 10.1002/ejic.201402543  1
2013 Wilson JJ, Lippard SJ. Oxidative Reactivity and Cytotoxic Properties of a Platinum(II) Complex Prepared by Outer-Sphere Amide Bond Coupling. Polyhedron. 58: 71-78. PMID 24489429 DOI: 10.1016/j.poly.2012.07.097  1
2013 Majumdar A, Lippard SJ. Non-heme mononitrosyldiiron complexes: importance of iron oxidation state in controlling the nature of the nitrosylated products. Inorganic Chemistry. 52: 13292-4. PMID 24246021 DOI: 10.1021/ic4019508  1
2013 Wisnovsky SP, Wilson JJ, Radford RJ, Pereira MP, Chan MR, Laposa RR, Lippard SJ, Kelley SO. Targeting mitochondrial DNA with a platinum-based anticancer agent. Chemistry & Biology. 20: 1323-8. PMID 24183971 DOI: 10.1016/j.chembiol.2013.08.010  1
2013 Xu X, Xie K, Zhang XQ, Pridgen EM, Park GY, Cui DS, Shi J, Wu J, Kantoff PW, Lippard SJ, Langer R, Walker GC, Farokhzad OC. Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug. Proceedings of the National Academy of Sciences of the United States of America. 110: 18638-43. PMID 24167294 DOI: 10.1073/pnas.1303958110  1
2013 Chung CY, Khurana V, Auluck PK, Tardiff DF, Mazzulli JR, Soldner F, Baru V, Lou Y, Freyzon Y, Cho S, Mungenast AE, Muffat J, Mitalipova M, Pluth MD, Jui NT, ... ... Lippard SJ, et al. Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons. Science (New York, N.Y.). 342: 983-7. PMID 24158904 DOI: 10.1126/science.1245296  1
2013 Ghosh M, van den Akker NM, Wijnands KA, Poeze M, Weber C, McQuade LE, Pluth MD, Lippard SJ, Post MJ, Molin DG, van Zandvoort MA. Specific visualization of nitric oxide in the vasculature with two-photon microscopy using a copper based fluorescent probe. Plos One. 8: e75331. PMID 24086509 DOI: 10.1371/journal.pone.0075331  1
2013 Suntharalingam K, Johnstone TC, Bruno PM, Lin W, Hemann MT, Lippard SJ. Bidentate ligands on osmium(VI) nitrido complexes control intracellular targeting and cell death pathways. Journal of the American Chemical Society. 135: 14060-3. PMID 24041161 DOI: 10.1021/ja4075375  1
2013 Song Y, Suntharalingam K, Yeung JS, Royzen M, Lippard SJ. Synthesis and characterization of Pt(IV) fluorescein conjugates to investigate Pt(IV) intracellular transformations. Bioconjugate Chemistry. 24: 1733-40. PMID 23957697 DOI: 10.1021/bc400281a  1
2013 Kellinger MW, Park GY, Chong J, Lippard SJ, Wang D. Effect of a monofunctional phenanthriplatin-DNA adduct on RNA polymerase II transcriptional fidelity and translesion synthesis. Journal of the American Chemical Society. 135: 13054-61. PMID 23927577 DOI: 10.1021/ja405475y  1
2013 Lin W, Buccella D, Lippard SJ. Visualization of peroxynitrite-induced changes of labile Zn2+ in the endoplasmic reticulum with benzoresorufin-based fluorescent probes. Journal of the American Chemical Society. 135: 13512-20. PMID 23902285 DOI: 10.1021/ja4059487  1
2013 Radford RJ, Chyan W, Lippard SJ. Peptide-based Targeting of Fluorescent Zinc Sensors to the Plasma Membrane of Live Cells. Chemical Science (Royal Society of Chemistry : 2010). 4: 3080-3084. PMID 23878718 DOI: 10.1039/C3SC50974E  1
2013 Johnstone TC, Lippard SJ. The effect of ligand lipophilicity on the nanoparticle encapsulation of Pt(IV) prodrugs. Inorganic Chemistry. 52: 9915-20. PMID 23859129 DOI: 10.1021/ic4010642  1
2013 Johnstone TC, Wilson JJ, Lippard SJ. Monofunctional and higher-valent platinum anticancer agents. Inorganic Chemistry. 52: 12234-49. PMID 23738524 DOI: 10.1021/ic400538c  1
2013 Huang Z, Zhang XA, Bosch M, Smith SJ, Lippard SJ. Tris(2-pyridylmethyl)amine (TPA) as a membrane-permeable chelator for interception of biological mobile zinc. Metallomics : Integrated Biometal Science. 5: 648-55. PMID 23715510 DOI: 10.1039/c3mt00103b  1
2013 Johnstone TC, Kulak N, Pridgen EM, Farokhzad OC, Langer R, Lippard SJ. Nanoparticle encapsulation of mitaplatin and the effect thereof on in vivo properties. Acs Nano. 7: 5675-83. PMID 23697579 DOI: 10.1021/nn401905g  1
2013 Zhu G, Song L, Lippard SJ. Visualizing inhibition of nucleosome mobility and transcription by cisplatin-DNA interstrand crosslinks in live mammalian cells. Cancer Research. 73: 4451-60. PMID 23695549 DOI: 10.1158/0008-5472.CAN-13-0198  1
2013 Li Y, Myae Soe CM, Wilson JJ, Tuang SL, Apfel UP, Lippard SJ. Triptycene-based Bis(benzimidazole) Carboxylate-Bridged Biomimetic Diiron(II) Complexes. European Journal of Inorganic Chemistry. 2013: 2011-2019. PMID 23585728 DOI: 10.1002/ejic.201201387  1
2013 Johnstone TC, Lippard SJ. Conformational Isomerism of trans-[Pt(NH2C6H11)2I2] and the Classical Wernerian Chemistry of [Pt(NH2C6H11)4]X2 (X = Cl, Br, I). Polyhedron. 52: 565-575. PMID 23554544 DOI: 10.1016/j.poly.2012.08.010  1
2013 Radford RJ, Lippard SJ. Chelators for investigating zinc metalloneurochemistry. Current Opinion in Chemical Biology. 17: 129-36. PMID 23478014 DOI: 10.1016/j.cbpa.2013.01.009  1
2013 Apfel UP, Buccella D, Wilson JJ, Lippard SJ. Detection of nitric oxide and nitroxyl with benzoresorufin-based fluorescent sensors. Inorganic Chemistry. 52: 3285-94. PMID 23461436 DOI: 10.1021/ic302793w  1
2013 Lu TT, Lee SJ, Apfel UP, Lippard SJ. Aging-associated enzyme human clock-1: substrate-mediated reduction of the diiron center for 5-demethoxyubiquinone hydroxylation. Biochemistry. 52: 2236-44. PMID 23445365 DOI: 10.1021/bi301674p  1
2013 Lee SJ, McCormick MS, Lippard SJ, Cho US. Control of substrate access to the active site in methane monooxygenase. Nature. 494: 380-4. PMID 23395959 DOI: 10.1038/nature11880  1
2013 Blakemore LJ, Tomat E, Lippard SJ, Trombley PQ. Zinc released from olfactory bulb glomeruli by patterned electrical stimulation of the olfactory nerve. Metallomics : Integrated Biometal Science. 5: 208-13. PMID 23392381 DOI: 10.1039/c3mt20158a  1
2013 Hope JM, Wilson JJ, Lippard SJ. Photoluminescent DNA binding and cytotoxic activity of a platinum(II) complex bearing a tetradentate β-diketiminate ligand. Dalton Transactions (Cambridge, England : 2003). 42: 3176-80. PMID 23143731 DOI: 10.1039/c2dt32462h  1
2013 Royzen M, Wilson JJ, Lippard SJ. Physical and structural properties of [Cu(BOT1)Cl]Cl, a fluorescent imaging probe for HNO. Journal of Inorganic Biochemistry. 118: 162-70. PMID 23102502 DOI: 10.1016/j.jinorgbio.2012.08.025  1
2013 Valencia PM, Pridgen EM, Perea B, Gadde S, Sweeney C, Kantoff PW, Bander NH, Lippard SJ, Langer R, Karnik R, Farokhzad OC. Synergistic cytotoxicity of irinotecan and cisplatin in dual-drug targeted polymeric nanoparticles. Nanomedicine (London, England). 8: 687-98. PMID 23075285 DOI: 10.2217/nnm.12.134  1
2012 Pluth MD, Lippard SJ. Reversible binding of nitric oxide to an Fe(III) complex of a tetra-amido macrocycle. Chemical Communications (Cambridge, England). 48: 11981-3. PMID 23133836 DOI: 10.1039/c2cc37221e  1
2012 Sartoretto JL, Kalwa H, Shiroto T, Sartoretto SM, Pluth MD, Lippard SJ, Michel T. Role of Ca2+ in the control of H2O2-modulated phosphorylation pathways leading to eNOS activation in cardiac myocytes. Plos One. 7: e44627. PMID 22970272 DOI: 10.1371/journal.pone.0044627  1
2012 Wilson JJ, Lippard SJ. Acetate-bridged platinum(III) complexes derived from cisplatin. Inorganic Chemistry. 51: 9852-64. PMID 22946515 DOI: 10.1021/ic301289j  1
2012 Park S, Lippard SJ. Binding interaction of HMGB4 with cisplatin-modified DNA. Biochemistry. 51: 6728-37. PMID 22901013 DOI: 10.1021/bi300649v  1
2012 Kozhukh J, Lippard SJ. Variable nitric oxide reactivity of tropocoronand cobalt(III) nitrite complexes as a function of the polymethylene linker chain length. Inorganic Chemistry. 51: 9416-22. PMID 22897687 DOI: 10.1021/ic3012266  1
2012 Wilson JJ, Lippard SJ. Modulation of Ligand Fluorescence by the Pt(II)/Pt(IV) Redox Couple. Inorganica Chimica Acta. 389: 77-84. PMID 22837584 DOI: 10.1016/j.ica.2011.12.034  1
2012 Park GY, Wilson JJ, Song Y, Lippard SJ. Phenanthriplatin, a monofunctional DNA-binding platinum anticancer drug candidate with unusual potency and cellular activity profile. Proceedings of the National Academy of Sciences of the United States of America. 109: 11987-92. PMID 22773807 DOI: 10.1073/pnas.1207670109  1
2012 Li Y, Wilson JJ, Do LH, Apfel UP, Lippard SJ. A C2-symmetric, basic Fe(III) carboxylate complex derived from a novel triptycene-based chelating carboxylate ligand. Dalton Transactions (Cambridge, England : 2003). 41: 9272-5. PMID 22751622 DOI: 10.1039/c2dt31260c  1
2012 Kozhukh J, Lippard SJ. Influence of tetraazamacrocyclic ligands on the nitric oxide reactivity of their cobalt(II) complexes. Journal of the American Chemical Society. 134: 11120-3. PMID 22742582 DOI: 10.1021/ja305011g  1
2012 Filipovic MR, Miljkovic JLj, Nauser T, Royzen M, Klos K, Shubina T, Koppenol WH, Lippard SJ, Ivanovi?-Burmazovi? I. Chemical characterization of the smallest S-nitrosothiol, HSNO; cellular cross-talk of H2S and S-nitrosothiols. Journal of the American Chemical Society. 134: 12016-27. PMID 22741609 DOI: 10.1021/ja3009693  1
2012 Kozhukh J, Lippard SJ. Zinc thiolate reactivity toward nitrogen oxides: insights into the interaction of Zn2+ with S-nitrosothiols and implications for nitric oxide synthase. Inorganic Chemistry. 51: 7346-53. PMID 22702952 DOI: 10.1021/ic3007684  1
2012 Lippard SJ. Bert Vallee, an extraordinary scientist. Journal of Inorganic Biochemistry. 111: 99. PMID 22677210 DOI: 10.1016/j.jinorgbio.2012.05.003  1
2012 Wilson JJ, Lippard SJ. In vitro anticancer activity of cis-diammineplatinum(II) complexes with β-diketonate leaving group ligands. Journal of Medicinal Chemistry. 55: 5326-36. PMID 22606945 DOI: 10.1021/jm3002857  1
2012 Graf N, Bielenberg DR, Kolishetti N, Muus C, Banyard J, Farokhzad OC, Lippard SJ. α(V)β(3) integrin-targeted PLGA-PEG nanoparticles for enhanced anti-tumor efficacy of a Pt(IV) prodrug. Acs Nano. 6: 4530-9. PMID 22584163 DOI: 10.1021/nn301148e  1
2012 Graf N, Mokhtari TE, Papayannopoulos IA, Lippard SJ. Platinum(IV)-chlorotoxin (CTX) conjugates for targeting cancer cells. Journal of Inorganic Biochemistry. 110: 58-63. PMID 22465700 DOI: 10.1016/j.jinorgbio.2012.02.012  1
2012 Graf N, Lippard SJ. Redox activation of metal-based prodrugs as a strategy for drug delivery. Advanced Drug Delivery Reviews. 64: 993-1004. PMID 22289471 DOI: 10.1016/j.addr.2012.01.007  1
2012 Huang Z, Lippard SJ. Illuminating mobile zinc with fluorescence from cuvettes to live cells and tissues. Methods in Enzymology. 505: 445-68. PMID 22289467 DOI: 10.1016/B978-0-12-388448-0.00031-0  1
2012 Do LH, Xue G, Que L, Lippard SJ. Evaluating the identity and diiron core transformations of a (μ-oxo)diiron(III) complex supported by electron-rich tris(pyridyl-2-methyl)amine ligands. Inorganic Chemistry. 51: 2393-402. PMID 22264120 DOI: 10.1021/ic202379b  1
2012 Zhu G, Myint M, Ang WH, Song L, Lippard SJ. Monofunctional platinum-DNA adducts are strong inhibitors of transcription and substrates for nucleotide excision repair in live mammalian cells. Cancer Research. 72: 790-800. PMID 22180496 DOI: 10.1158/0008-5472.CAN-11-3151  1
2012 Kozhukh J, Fedoce Lopes J, Dos Santos HF, Lippard SJ. Reactions of organozinc thiolates with nitrosonium ion: C -nitroso formation by possible transnitrosation Organometallics. 31: 8063-8066. DOI: 10.1021/om300922m  1
2011 Rosenthal J, Nepomnyashchii AB, Kozhukh J, Bard AJ, Lippard SJ. Synthesis, Photophysics, Electrochemistry and Electrogenerated Chemiluminescence of a Homologous Set of BODIPY-Appended Bipyridine Derivatives. The Journal of Physical Chemistry. C, Nanomaterials and Interfaces. 115: 17993-18001. PMID 23181151 DOI: 10.1021/jp204487r  1
2011 McCormick MS, Lippard SJ. Analysis of substrate access to active sites in bacterial multicomponent monooxygenase hydroxylases: X-ray crystal structure of xenon-pressurized phenol hydroxylase from Pseudomonas sp. OX1. Biochemistry. 50: 11058-69. PMID 22136180 DOI: 10.1021/bi201248b  1
2011 Do LH, Lippard SJ. Evolution of strategies to prepare synthetic mimics of carboxylate-bridged diiron protein active sites. Journal of Inorganic Biochemistry. 105: 1774-85. PMID 22113107 DOI: 10.1016/j.jinorgbio.2011.08.025  1
2011 Tennyson AG, Lippard SJ. Generation, translocation, and action of nitric oxide in living systems. Chemistry & Biology. 18: 1211-20. PMID 22035790 DOI: 10.1016/j.chembiol.2011.09.009  1
2011 You Y, Lee S, Kim T, Ohkubo K, Chae WS, Fukuzumi S, Jhon GJ, Nam W, Lippard SJ. Phosphorescent sensor for biological mobile zinc. Journal of the American Chemical Society. 133: 18328-42. PMID 22023085 DOI: 10.1021/ja207163r  1
2011 Pan E, Zhang XA, Huang Z, Krezel A, Zhao M, Tinberg CE, Lippard SJ, McNamara JO. Vesicular zinc promotes presynaptic and inhibits postsynaptic long-term potentiation of mossy fiber-CA3 synapse. Neuron. 71: 1116-26. PMID 21943607 DOI: 10.1016/j.neuron.2011.07.019  1
2011 Do LH, Wang H, Tinberg CE, Dowty E, Yoda Y, Cramer SP, Lippard SJ. Characterization of a synthetic peroxodiiron(III) protein model complex by nuclear resonance vibrational spectroscopy. Chemical Communications (Cambridge, England). 47: 10945-7. PMID 21897991 DOI: 10.1039/c1cc13836g  1
2011 Sartoretto JL, Kalwa H, Pluth MD, Lippard SJ, Michel T. Hydrogen peroxide differentially modulates cardiac myocyte nitric oxide synthesis. Proceedings of the National Academy of Sciences of the United States of America. 108: 15792-7. PMID 21896719 DOI: 10.1073/pnas.1111331108  1
2011 Pluth MD, Chan MR, McQuade LE, Lippard SJ. Seminaphthofluorescein-based fluorescent probes for imaging nitric oxide in live cells. Inorganic Chemistry. 50: 9385-92. PMID 21895023 DOI: 10.1021/ic200986v  1
2011 Li Y, Cao R, Lippard SJ. Design and synthesis of a novel triptycene-based ligand for modeling carboxylate-bridged diiron enzyme active sites. Organic Letters. 13: 5052-5. PMID 21875093 DOI: 10.1021/ol201882v  1
2011 Cao R, McCarthy BD, Lippard SJ. Immobilization, trapping, and anion exchange of perrhenate ion using copper-based tripodal complexes. Inorganic Chemistry. 50: 9499-507. PMID 21870794 DOI: 10.1021/ic201172r  1
2011 Song WJ, Gucinski G, Sazinsky MH, Lippard SJ. Tracking a defined route for Oâ‚‚ migration in a dioxygen-activating diiron enzyme. Proceedings of the National Academy of Sciences of the United States of America. 108: 14795-800. PMID 21859951 DOI: 10.1073/pnas.1106514108  1
2011 Lovejoy KS, Serova M, Bieche I, Emami S, D'Incalci M, Broggini M, Erba E, Gespach C, Cvitkovic E, Faivre S, Raymond E, Lippard SJ. Spectrum of cellular responses to pyriplatin, a monofunctional cationic antineoplastic platinum(II) compound, in human cancer cells. Molecular Cancer Therapeutics. 10: 1709-19. PMID 21750216 DOI: 10.1158/1535-7163.MCT-11-0250  1
2011 You Y, Han Y, Lee YM, Park SY, Nam W, Lippard SJ. Phosphorescent sensor for robust quantification of copper(II) ion. Journal of the American Chemical Society. 133: 11488-91. PMID 21749087 DOI: 10.1021/ja204997c  1
2011 Do LH, Lippard SJ. Toward functional carboxylate-bridged diiron protein mimics: achieving structural stability and conformational flexibility using a macrocylic ligand framework. Journal of the American Chemical Society. 133: 10568-81. PMID 21682286 DOI: 10.1021/ja2021312  1
2011 Pluth MD, Tomat E, Lippard SJ. Biochemistry of mobile zinc and nitric oxide revealed by fluorescent sensors. Annual Review of Biochemistry. 80: 333-55. PMID 21675918 DOI: 10.1146/annurev-biochem-061009-091643  1
2011 Song WJ, Lippard SJ. Mechanistic studies of reactions of peroxodiiron(III) intermediates in T201 variants of toluene/o-xylene monooxygenase hydroxylase. Biochemistry. 50: 5391-9. PMID 21595439 DOI: 10.1021/bi200340f  1
2011 Bochevarov AD, Li J, Song WJ, Friesner RA, Lippard SJ. Insights into the different dioxygen activation pathways of methane and toluene monooxygenase hydroxylases. Journal of the American Chemical Society. 133: 7384-97. PMID 21517016 DOI: 10.1021/ja110287y  1
2011 Graf N, Ang WH, Zhu G, Myint M, Lippard SJ. Role of endonucleases XPF and XPG in nucleotide excision repair of platinated DNA and cisplatin/oxaliplatin cytotoxicity. Chembiochem : a European Journal of Chemical Biology. 12: 1115-23. PMID 21452186 DOI: 10.1002/cbic.201000724  1
2011 Tinberg CE, Lippard SJ. Dioxygen activation in soluble methane monooxygenase. Accounts of Chemical Research. 44: 280-8. PMID 21391602 DOI: 10.1021/ar1001473  1
2011 Tinberg CE, Song WJ, Izzo V, Lippard SJ. Multiple roles of component proteins in bacterial multicomponent monooxygenases: phenol hydroxylase and toluene/o-xylene monooxygenase from Pseudomonas sp. OX1. Biochemistry. 50: 1788-98. PMID 21366224 DOI: 10.1021/bi200028z  1
2011 Wilson JJ, Lippard SJ. Synthesis, characterization, and cytotoxicity of platinum(IV) carbamate complexes. Inorganic Chemistry. 50: 3103-15. PMID 21361279 DOI: 10.1021/ic2000816  1
2011 Park S, Lippard SJ. Redox state-dependent interaction of HMGB1 and cisplatin-modified DNA. Biochemistry. 50: 2567-74. PMID 21355578 DOI: 10.1021/bi2000214  1
2011 Buccella D, Horowitz JA, Lippard SJ. Understanding zinc quantification with existing and advanced ditopic fluorescent Zinpyr sensors. Journal of the American Chemical Society. 133: 4101-14. PMID 21351756 DOI: 10.1021/ja110907m  1
2011 Tonzetich ZJ, Héroguel F, Do LH, Lippard SJ. Chemistry of nitrosyliron complexes supported by a β-diketiminate ligand. Inorganic Chemistry. 50: 1570-9. PMID 21244036 DOI: 10.1021/ic102300d  1
2011 Dhar S, Kolishetti N, Lippard SJ, Farokhzad OC. Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 108: 1850-5. PMID 21233423 DOI: 10.1073/pnas.1011379108  1
2011 Dhar S, Lippard SJ. Current Status and Mechanism of Action of Platinum-Based Anticancer Drugs Bioinorganic Medicinal Chemistry. 79-95. DOI: 10.1002/9783527633104.ch3  1
2011 Lippard SJ. Foreword Letters to a Young Chemist. vii-xi. DOI: 10.1002/9781118007099  1
2010 Bochevarov AD, Friesner RA, Lippard SJ. The prediction of Fe Mössbauer parameters by the density functional theory: a benchmark study. Journal of Chemical Theory and Computation. 6: 3735-3749. PMID 21258606 DOI: 10.1021/ct100398m  1
2010 Todd RC, Lippard SJ. Consequences of cisplatin binding on nucleosome structure and dynamics Chemistry and Biology. 17: 1334-1343. PMID 21168769 DOI: 10.1016/j.chembiol.2010.10.018  1
2010 Tinberg CE, Tonzetich ZJ, Wang H, Do LH, Yoda Y, Cramer SP, Lippard SJ. Characterization of iron dinitrosyl species formed in the reaction of nitric oxide with a biological Rieske center. Journal of the American Chemical Society. 132: 18168-76. PMID 21133361 DOI: 10.1021/ja106290p  1
2010 Cao R, Müller P, Lippard SJ. Tripodal tris-tacn and tris-dpa platforms for assembling phosphate-templated trimetallic centers Journal of the American Chemical Society. 132: 17366-17369. PMID 21090678 DOI: 10.1021/ja108212v  1
2010 Du P, Lippard SJ. A highly selective turn-on colorimetric, red fluorescent sensor for detecting mobile zinc in living cells. Inorganic Chemistry. 49: 10753-5. PMID 21028775 DOI: 10.1021/ic101569a  1
2010 Lippard SJ. The interface of inorganic chemistry and biology Journal of the American Chemical Society. 132: 14689-14693. PMID 20923238 DOI: 10.1021/ja108523h  1
2010 Behan RK, Lippard SJ. The aging-associated enzyme CLK-1 is a member of the carboxylate-bridged diiron family of proteins Biochemistry. 49: 9679-9681. PMID 20923139 DOI: 10.1021/bi101475z  1
2010 Kolishetti N, Dhar S, Valencia PM, Lin LQ, Karnik R, Lippard SJ, Langer R, Farokhzad OC. Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy. Proceedings of the National Academy of Sciences of the United States of America. 107: 17939-44. PMID 20921363 DOI: 10.1073/pnas.1011368107  1
2010 Tomat E, Lippard SJ. Ratiometric and intensity-based zinc sensors built on rhodol and rhodamine platforms. Inorganic Chemistry. 49: 9113-5. PMID 20860360 DOI: 10.1021/ic101513a  1
2010 McQuade LE, Lippard SJ. Cell-trappable quinoline-derivatized fluoresceins for selective and reversible biological Zn(II) detection Inorganic Chemistry. 49: 9535-9545. PMID 20849126 DOI: 10.1021/ic1012507  1
2010 Song WJ, McCormick MS, Behan RK, Sazinsky MH, Jiang W, Lin J, Krebs C, Lippard SJ. Active site threonine facilitates proton transfer during dioxygen activation at the diiron center of toluene/o-xylene monooxygenase hydroxylase. Journal of the American Chemical Society. 132: 13582-5. PMID 20839885 DOI: 10.1021/ja1063795  1
2010 McQuade LE, Pluth MD, Lippard SJ. Mechanism of nitric oxide reactivity and fluorescence enhancement of the NO-specific probe CuFL1. Inorganic Chemistry. 49: 8025-33. PMID 20704359 DOI: 10.1021/ic101054u  1
2010 McQuade LE, Lippard SJ. Fluorescence-based nitric oxide sensing by Cu(II) complexes that can be trapped in living cells Inorganic Chemistry. 49: 7464-7471. PMID 20690755 DOI: 10.1021/ic100802q  1
2010 Tinberg CE, Lippard SJ. Oxidation reactions performed by soluble methane monooxygenase hydroxylase intermediates Hperoxo and Q proceed by distinct mechanisms Biochemistry. 49: 7902-7912. PMID 20681546 DOI: 10.1021/bi1009375  1
2010 Tonzetich ZJ, McQuade LE, Lippard SJ. Detecting and understanding the roles of nitric oxide in biology. Inorganic Chemistry. 49: 6338-48. PMID 20666391 DOI: 10.1021/ic9022757  1
2010 Ghosh SK, Kim P, Zhang XA, Yun SH, Moore A, Lippard SJ, Medarova Z. A novel imaging approach for early detection of prostate cancer based on endogenous zinc sensing. Cancer Research. 70: 6119-27. PMID 20610630 DOI: 10.1158/0008-5472.CAN-10-1008  1
2010 Lee T, Zhang XA, Dhar S, Faas H, Lippard SJ, Jasanoff A. In vivo imaging with a cell-permeable porphyrin-based MRI contrast agent. Chemistry & Biology. 17: 665-73. PMID 20609416 DOI: 10.1016/j.chembiol.2010.05.009  1
2010 Zhu G, Chang P, Lippard SJ. Recognition of platinum-DNA damage by poly(ADP-ribose) polymerase-1. Biochemistry. 49: 6177-83. PMID 20550106 DOI: 10.1021/bi100775t  1
2010 Todd RC, Lippard SJ. Structure of duplex DNA containing the cisplatin 1,2-{Pt(NH3)2}2+-d(GpG) cross-link at 1.77Å resolution Journal of Inorganic Biochemistry. 104: 902-908. PMID 20541266 DOI: 10.1016/j.jinorgbio.2010.04.005  1
2010 Friedle S, Reisner E, Lippard SJ. Current challenges of modeling diiron enzyme active sites for dioxygen activation by biomimetic synthetic complexes Chemical Society Reviews. 39: 2768-2779. PMID 20485834 DOI: 10.1039/c003079c  1
2010 You Y, Tomat E, Hwang K, Atanasijevic T, Nam W, Jasanoff AP, Lippard SJ. Manganese displacement from Zinpyr-1 allows zinc detection by fluorescence microscopy and magnetic resonance imaging. Chemical Communications (Cambridge, England). 46: 4139-41. PMID 20454746 DOI: 10.1039/c0cc00179a  1
2010 Wang D, Zhu G, Huang X, Lippard SJ. X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct. Proceedings of the National Academy of Sciences of the United States of America. 107: 9584-9. PMID 20448203 DOI: 10.1073/pnas.1002565107  1
2010 Ang WH, Myint M, Lippard SJ. Transcription inhibition by platinum-DNA cross-links in live mammalian cells Journal of the American Chemical Society. 132: 7429-7435. PMID 20443565 DOI: 10.1021/ja101495v  1
2010 Tonzetich ZJ, Wang H, Mitra D, Tinberg CE, Do LH, Jenney FE, Adams MW, Cramer SP, Lippard SJ. Identification of protein-bound dinitrosyl iron complexes by nuclear resonance vibrational spectroscopy. Journal of the American Chemical Society. 132: 6914-6. PMID 20429508 DOI: 10.1021/ja101002f  1
2010 Wilson JJ, Fedoce Lopes J, Lippard SJ. Synthesis, characterization, and photophysical properties of three platinum(II) complexes bearing fluorescent analogues of the Di-2-pyridylmethane ligand. Inorganic Chemistry. 49: 5303-15. PMID 20423108 DOI: 10.1021/ic100411p  1
2010 McQuade LE, Ma J, Lowe G, Ghatpande A, Gelperin A, Lippard SJ. Visualization of nitric oxide production in the mouse main olfactory bulb by a cell-trappable copper(II) fluorescent probe. Proceedings of the National Academy of Sciences of the United States of America. 107: 8525-30. PMID 20413724 DOI: 10.1073/pnas.0914794107  1
2010 Pluth MD, McQuade LE, Lippard SJ. Cell-trappable fluorescent probes for nitric oxide visualization in living cells. Organic Letters. 12: 2318-21. PMID 20405852 DOI: 10.1021/ol1006289  1
2010 Oliver TG, Mercer KL, Sayles LC, Burke JR, Mendus D, Lovejoy KS, Cheng MH, Subramanian A, Mu D, Powers S, Crowley D, Bronson RT, Whittaker CA, Bhutkar A, Lippard SJ, et al. Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer. Genes & Development. 24: 837-52. PMID 20395368 DOI: 10.1101/gad.1897010  1
2010 Rosenthal J, Lippard SJ. Direct detection of nitroxyl in aqueous solution using a tripodal copper(II) BODIPY complex. Journal of the American Chemical Society. 132: 5536-7. PMID 20355724 DOI: 10.1021/ja909148v  1
2010 Tangen E, Conradie J, Franz K, Friedle S, Telser J, Lippard SJ, Ghosh A. Electronic structure of a paramagnetic {MNO}6 complex: MnNO 5,5-tropocoronand Inorganic Chemistry. 49: 2701-2705. PMID 20166686 DOI: 10.1021/ic901860x  1
2010 Atanasijevic T, Zhang XA, Lippard SJ, Jasanoff A. MRI sensing based on the displacement of paramagnetic ions from chelated complexes. Inorganic Chemistry. 49: 2589-91. PMID 20141114 DOI: 10.1021/ic100150e  1
2010 Tomat E, Lippard SJ. Imaging mobile zinc in biology. Current Opinion in Chemical Biology. 14: 225-30. PMID 20097117 DOI: 10.1016/j.cbpa.2009.12.010  1
2010 Do LH, Hayashi T, Moënne-Loccoz P, Lippard SJ. Carboxylate as the protonation site in (Peroxo)diiron(III) model complexes of soluble methane monooxygenase and related diiron proteins. Journal of the American Chemical Society. 132: 1273-5. PMID 20055391 DOI: 10.1021/ja909718f  1
2010 McQuade LE, Lippard SJ. Fluorescent probes to investigate nitric oxide and other reactive nitrogen species in biology (truncated form: fluorescent probes of reactive nitrogen species) Current Opinion in Chemical Biology. 14: 43-49. PMID 19926519 DOI: 10.1016/j.cbpa.2009.10.004  1
2009 Todd RC, Lippard SJ. Inhibition of transcription by platinum antitumor compounds Metallomics. 1: 280-291. PMID 20046924 DOI: 10.1039/b907567d  1
2009 Lovejoy KS, Lippard SJ. Non-traditional platinum compounds for improved accumulation, oral bioavailability, and tumor targeting Dalton Transactions. 10651-10659. PMID 20023892 DOI: 10.1039/b913896j  1
2009 Dhar S, Lippard SJ. Mitaplatin, a potent fusion of cisplatin and the orphan drug dichloroacetate Proceedings of the National Academy of Sciences of the United States of America. 106: 22199-22204. PMID 20007777 DOI: 10.1073/pnas.0912276106  1
2009 Tinberg CE, Lippard SJ. Revisiting the mechanism of dioxygen activation in soluble methane monooxygenase from M. capsulatus (Bath): Evidence for a multi-step, proton-dependent reaction pathway Biochemistry. 48: 12145-12158. PMID 19921958 DOI: 10.1021/bi901672n  1
2009 Do LH, Lippard SJ. 2-Phenoxypyridyl dinucleating ligands for assembly of diiron(II) complexes: efficient reactivity with O(2) to form (mu-Oxo)diiron(III) units. Inorganic Chemistry. 48: 10708-19. PMID 19845332 DOI: 10.1021/ic901711c  1
2009 Ang WH, Lippard SJ. Functional consequence of plasmid DNA modified site-specifically with 7-deaza-deoxyadenosine at a single, programmable site Chemical Communications. 5820-5822. PMID 19787108 DOI: 10.1039/b914843d  1
2009 Dhar S, Daniel WL, Giljohann DA, Mirkin CA, Lippard SJ. Polyvalent oligonucleotide gold nanoparticle conjugates as delivery vehicles for platinum(IV) warheads. Journal of the American Chemical Society. 131: 14652-3. PMID 19778015 DOI: 10.1021/ja9071282  1
2009 Friedle S, Kodanko JJ, Morys AJ, Hayashi T, Moënne-Loccoz P, Lippard SJ. Modeling the syn disposition of nitrogen donors in non-heme diiron enzymes. Synthesis, characterization, and hydrogen peroxide reactivity of diiron(III) complexes with the syn N-donor ligand H2BPG2DEV. Journal of the American Chemical Society. 131: 14508-20. PMID 19757795 DOI: 10.1021/ja906137y  1
2009 Wong BA, Friedle S, Lippard SJ. Subtle modification of 2.2-dipicolylamine lowers the affinity and improves the turn-on of Zn(II)-selective fluorescent sensors Inorganic Chemistry. 48: 7009-7011. PMID 19572729 DOI: 10.1021/ic900990w  1
2009 Tonzetich ZJ, Do LH, Lippard SJ. Dinitrosyl iron complexes relevant to Rieske cluster nitrosylation. Journal of the American Chemical Society. 131: 7964-5. PMID 19459625 DOI: 10.1021/ja9030159  1
2009 Wong BA, Friedle S, Lippard SJ. Solution and fluorescence properties of symmetric dipicolylamine-containing dichlorofluorescein-based Zn sensors Journal of the American Chemical Society. 131: 7142-7152. PMID 19405465 DOI: 10.1021/ja900980u  1
2009 Zhu G, Lippard SJ. Photoaffinity labeling reveals nuclear proteins that uniquely recognize cisplatin-DNA interstrand cross-links. Biochemistry. 48: 4916-25. PMID 19364127 DOI: 10.1021/bi900389b  1
2009 Song WJ, Behan RK, Naik SG, Huynh BH, Lippard SJ. Characterization of a peroxodiiron(III) intermediate in the T201S variant of toluene/o-xylene monooxygenase hydroxylase from Pseudomonas sp. OX1. Journal of the American Chemical Society. 131: 6074-5. PMID 19354250 DOI: 10.1021/ja9011782  1
2009 Wee HA, Brown WW, Lippard SJ. Preparation of mammalian expression vectors incorporating site-specifically platinated-DNA lesions Bioconjugate Chemistry. 20: 1058-1063. PMID 19351185 DOI: 10.1021/bc900031a  1
2009 Altmann KH, Buchner J, Kessler H, Diederich F, Kräutler B, Lippard S, Liskamp R, Müller K, Nolan EM, Samori B, Schneider G, Schreiber SL, Schwalbe H, Toniolo C, van Boeckel CA, et al. The state of the art of chemical biology. Chembiochem : a European Journal of Chemical Biology. 10: 16-29. PMID 19115274 DOI: 10.1002/cbic.200800758  1
2009 Guggenheim ER, Xu D, Zhang CX, Chang PV, Lippard SJ. Photoaffinity isolation and identification of proteins in cancer cell extracts that bind to platinum-modified DNA. Chembiochem : a European Journal of Chemical Biology. 10: 141-57. PMID 19053130 DOI: 10.1002/cbic.200800471  1
2009 Nolan EM, Lippard SJ. Small-molecule fluorescent sensors for investigating zinc metalloneurochemistry. Accounts of Chemical Research. 42: 193-203. PMID 18989940 DOI: 10.1021/ar8001409  1
2009 Friedle S, Lippard SJ. Synthesis, characterization, and oxygenation studies of carboxlate-bridged diiron(II) complexes with aromatic substrates tethered to pyridine ligands and the formation of a unique trinuclear complex European Journal of Inorganic Chemistry. 5506-5515. DOI: 10.1002/ejic.200900821  1
2008 Friedle S, Kodanko JJ, Fornace KL, Lippard SJ. 9-Triptycenecarboxylate-Bridged Diiron(II) Complexes: Capture of the Paddlewheel Geometric Isomer. Journal of Molecular Structure. 890: 317-327. PMID 19915653 DOI: 10.1016/j.molstruc.2008.05.030  1
2008 Dhar S, Gu FX, Langer R, Farokhza OC, Lippard SJ. Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA - PEG nanoparticles Proceedings of the National Academy of Sciences of the United States of America. 105: 17356-17361. PMID 18978032 DOI: 10.1073/pnas.0809154105  1
2008 Guggenheim ER, Ondrus AE, Movassaghi M, Lippard SJ. Poly(ADP-ribose) polymerase-1 activity facilitates the dissociation of nuclear proteins from platinum-modified DNA Bioorganic and Medicinal Chemistry. 16: 10121-10128. PMID 18977144 DOI: 10.1016/j.bmc.2008.09.074  1
2008 Zhang XA, Hayes D, Smith SJ, Friedle S, Lippard SJ. New strategy for quantifying biological zinc by a modified zinpyr fluorescence sensor. Journal of the American Chemical Society. 130: 15788-9. PMID 18975868 DOI: 10.1021/ja807156b  1
2008 Tomat E, Nolan EM, Jaworski J, Lippard SJ. Organelle-specific zinc detection using zinpyr-labeled fusion proteins in live cells. Journal of the American Chemical Society. 130: 15776-7. PMID 18973293 DOI: 10.1021/ja806634e  1
2008 Harrop TC, Tonzetich ZJ, Reisner E, Lippard SJ. Reactions of synthetic [2Fe-2S] and [4Fe-4S] clusters with nitric oxide and nitrosothiols. Journal of the American Chemical Society. 130: 15602-10. PMID 18939795 DOI: 10.1021/ja8054996  1
2008 Tennyson AG, Dhar S, Lippard SJ. Synthesis and characterization of {Ni(NO)}10 and {Co(NO) 2}10 complexes supported by thiolate ligands Journal of the American Chemical Society. 130: 15087-15098. PMID 18928257 DOI: 10.1021/ja803992y  1
2008 Dhar S, Liu Z, Thomale J, Dai H, Lippard SJ. Targeted single-wall carbon nanotube-mediated Pt(IV) prodrug delivery using folate as a homing device. Journal of the American Chemical Society. 130: 11467-76. PMID 18661990 DOI: 10.1021/ja803036e  1
2008 Nolan EM, Lippard SJ. Tools and tactics for the optical detection of mercuric ion. Chemical Reviews. 108: 3443-80. PMID 18652512 DOI: 10.1021/cr068000q  1
2008 Lovejoy KS, Todd RC, Zhang S, McCormick MS, D'Aquino JA, Reardon JT, Sancar A, Giacomini KM, Lippard SJ. cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects. Proceedings of the National Academy of Sciences of the United States of America. 105: 8902-7. PMID 18579768 DOI: 10.1073/pnas.0803441105  1
2008 Kodanko JJ, Lippard SJ. Synthesis and Characterization of a Ditriflate-Bridged, Diiron(II) Complex with Syn-N-Donor Ligands: [Fe(2)(μ-OTf)(2)(PIC(2)DET)(2)](BARF)(2). Inorganica Chimica Acta. 361: 894-900. PMID 18458751 DOI: 10.1016/j.ica.2007.02.029  1
2008 Zhao M, Helms B, Slonkina E, Friedle S, Lee D, Dubois J, Hedman B, Hodgson KO, Fréchet JM, Lippard SJ. Iron complexes of dendrimer-appended carboxylates for activating dioxygen and oxidizing hydrocarbons. Journal of the American Chemical Society. 130: 4352-63. PMID 18331028 DOI: 10.1021/ja076817a  1
2008 Ober M, Lippard SJ. A 1,2-d(GpG) cisplatin intrastrand cross-link influences the rotational and translational setting of DNA in nucleosomes Journal of the American Chemical Society. 130: 2851-2861. PMID 18269283 DOI: 10.1021/ja710220x  1
2008 Shatalin K, Gusarov I, Avetissova E, Shatalina Y, McQuade LE, Lippard SJ, Nudler E. Bacillus anthracis-derived nitric oxide is essential for pathogen virulence and survival in macrophages Proceedings of the National Academy of Sciences of the United States of America. 105: 1009-1013. PMID 18215992 DOI: 10.1073/pnas.0710950105  1
2008 Zhang XA, Song D, Lippard SJ. A reversible pH-dependent intramolecular pyridine-aldehyde cyclization. The Journal of Organic Chemistry. 73: 734-7. PMID 18081350 DOI: 10.1021/jo702394v  0.76
2008 Gusarov I, Starodubtseva M, Wang ZQ, McQuade L, Lippard SJ, Stuehr DJ, Nudler E. Bacterial nitric-oxide synthases operate without a dedicated redox partner (Journal of Biological Chemistry (2008) 283, (13140-13147)) Journal of Biological Chemistry. 283: 19164. DOI: 10.1074/jbc.M710178200  1
2008 Tinberg CE, Beauvais LG, Lippard SJ. Hydrocarbon oxidation by the catalytic intermediates in soluble methane monooxygenase from Methylococcus capsulatus (Bath) Acs National Meeting Book of Abstracts 1
2007 Murray LJ, García-Serres R, McCormick MS, Davydov R, Naik SG, Kim SH, Hoffman BM, Huynh BH, Lippard SJ. Dioxygen activation at non-heme diiron centers: oxidation of a proximal residue in the I100W variant of toluene/o-xylene monooxygenase hydroxylase. Biochemistry. 46: 14795-809. PMID 18044971 DOI: 10.1021/bi7017128  1
2007 Murray LJ, Naik SG, Ortillo DO, García-Serres R, Lee JK, Huynh BH, Lippard SJ. Characterization of the arene-oxidizing intermediate in ToMOH as a diiron(III) species. Journal of the American Chemical Society. 129: 14500-10. PMID 17967027 DOI: 10.1021/ja076121h  1
2007 Conradie J, Quarless DA, Hsu HF, Harrop TC, Lippard SJ, Koch SA, Ghosh A. Electronic structure and FeNO conformation of nonheme iron-thiolate-NO complexes: an experimental and DFT study. Journal of the American Chemical Society. 129: 10446-56. PMID 17685516 DOI: 10.1021/ja0719982  1
2007 Harrop TC, Song D, Lippard SJ. Reactivity pathways for nitric oxide and nitrosonium with iron complexes in biologically relevant sulfur coordination spheres. Journal of Inorganic Biochemistry. 101: 1730-8. PMID 17618690 DOI: 10.1016/j.jinorgbio.2007.05.006  1
2007 Zhang XA, Lovejoy KS, Jasanoff A, Lippard SJ. Water-soluble porphyrins as a dual-function molecular imaging platform for MRI and fluorescence zinc sensing. Proceedings of the National Academy of Sciences of the United States of America. 104: 10780-5. PMID 17578918 DOI: 10.1073/pnas.0702393104  1
2007 Murray LJ, Lippard SJ. Substrate trafficking and dioxygen activation in bacterial multicomponent monooxygenases. Accounts of Chemical Research. 40: 466-74. PMID 17518435 DOI: 10.1021/ar600040e  0.68
2007 Nolan EM, Lippard SJ. Turn-on and ratiometric mercury sensing in water with a red-emitting probe. Journal of the American Chemical Society. 129: 5910-8. PMID 17429971 DOI: 10.1021/ja068879r  1
2007 Mantri Y, Lippard SJ, Baik MH. Bifunctional binding of cisplatin to DNA: why does cisplatin form 1,2-intrastrand cross-links with ag but not with GA? Journal of the American Chemical Society. 129: 5023-30. PMID 17402732 DOI: 10.1021/ja067631z  1
2007 Rinaldo D, Philipp DM, Lippard SJ, Friesner RA. Intermediates in dioxygen activation by methane monooxygenase: a QM/MM study. Journal of the American Chemical Society. 129: 3135-47. PMID 17326634 DOI: 10.1021/ja0654074  1
2007 Newcomb M, Lansakara-P DS, Kim HY, Chandrasena RE, Lippard SJ, Beauvais LG, Murray LJ, Izzo V, Hollenberg PF, Coon MJ. Products from enzyme-catalyzed oxidations of norcarenes. The Journal of Organic Chemistry. 72: 1128-33. PMID 17288367 DOI: 10.1021/jo061865j  1
2007 Newcomb M, Chandrasena RE, Lansakara-P DS, Kim HY, Lippard SJ, Beauvais LG, Murray LJ, Izzo V, Hollenberg PF, Coon MJ. Desaturase reactions complicate the use of norcarane as a mechanistic probe. Unraveling the mixture of twenty-plus products formed in enzyme-catalyzed oxidations of norcarane. The Journal of Organic Chemistry. 72: 1121-7. PMID 17288366 DOI: 10.1021/jo061864r  1
2007 Lim MH, Lippard SJ. Metal-based turn-on fluorescent probes for sensing nitric oxide. Accounts of Chemical Research. 40: 41-51. PMID 17226944 DOI: 10.1021/ar950149t  1
2006 Nolan EM, Ryu JW, Jaworski J, Feazell RP, Sheng M, Lippard SJ. Zinspy sensors with enhanced dynamic range for imaging neuronal cell zinc uptake and mobilization. Journal of the American Chemical Society. 128: 15517-28. PMID 17132019 DOI: 10.1021/ja065759a  1
2006 Nolan EM, Jaworski J, Racine ME, Sheng M, Lippard SJ. Midrange affinity fluorescent Zn(II) sensors of the Zinpyr family: syntheses, characterization, and biological imaging applications. Inorganic Chemistry. 45: 9748-57. PMID 17112271 DOI: 10.1021/ic061137e  1
2006 Smith RC, Tennyson AG, Won AC, Lippard SJ. Conjugated metallopolymers for fluorescent turn-on detection of nitric oxide. Inorganic Chemistry. 45: 9367-73. PMID 17083235 DOI: 10.1021/ic061099z  1
2006 Lim MH, Wong BA, Pitcock WH, Mokshagundam D, Baik MH, Lippard SJ. Direct nitric oxide detection in aqueous solution by copper(II) fluorescein complexes. Journal of the American Chemical Society. 128: 14364-73. PMID 17076510 DOI: 10.1021/ja064955e  1
2006 Do L, Smith RC, Tennyson AG, Lippard SJ. Luminescent properties of water-soluble conjugated metallopolymers and their application to fluorescent nitric oxide detection. Inorganic Chemistry. 45: 8998-9005. PMID 17054360 DOI: 10.1021/ic060998k  1
2006 Lim MH, Lippard SJ. Fluorescent nitric oxide detection by copper complexes bearing anthracenyl and dansyl fluorophore ligands. Inorganic Chemistry. 45: 8980-9. PMID 17054358 DOI: 10.1021/ic0609913  1
2006 Lieberman RL, Kondapalli KC, Shrestha DB, Hakemian AS, Smith SM, Telser J, Kuzelka J, Gupta R, Borovik AS, Lippard SJ, Hoffman BM, Rosenzweig AC, Stemmler TL. Characterization of the particulate methane monooxygenase metal centers in multiple redox states by X-ray absorption spectroscopy. Inorganic Chemistry. 45: 8372-81. PMID 16999437 DOI: 10.1021/ic060739v  1
2006 Goldsmith CR, Lippard SJ. Analogues of Zinpyr-1 provide insight into the mechanism of zinc sensing. Inorganic Chemistry. 45: 6474-8. PMID 16878961 DOI: 10.1021/ic060378j  1
2006 Smith RC, Tennyson AG, Lippard SJ. Polymer-bound dirhodium tetracarboxylate films for fluorescent detection of nitric oxide. Inorganic Chemistry. 45: 6222-6. PMID 16878931 DOI: 10.1021/ic060070s  1
2006 Lim MH, Kuang C, Lippard SJ. Nitric oxide-induced fluorescence enhancement by displacement of dansylated ligands from cobalt. Chembiochem : a European Journal of Chemical Biology. 7: 1571-6. PMID 16789059 DOI: 10.1002/cbic.200600042  1
2006 Murray LJ, García-Serres R, Naik S, Huynh BH, Lippard SJ. Dioxygen activation at non-heme diiron centers: characterization of intermediates in a mutant form of toluene/o-xylene monooxygenase hydroxylase. Journal of the American Chemical Society. 128: 7458-9. PMID 16756297 DOI: 10.1021/ja062762l  1
2006 Lim MH, Xu D, Lippard SJ. Visualization of nitric oxide in living cells by a copper-based fluorescent probe. Nature Chemical Biology. 2: 375-80. PMID 16732295 DOI: 10.1038/nchembio794  1
2006 Harrop TC, Song D, Lippard SJ. Interaction of nitric oxide with tetrathiolato iron(II) complexes: relevance to the reaction pathways of iron nitrosyls in sulfur-rich biological coordination environments. Journal of the American Chemical Society. 128: 3528-9. PMID 16536520 DOI: 10.1021/ja060186n  1
2006 Nolan EM, Racine ME, Lippard SJ. Selective Hg(II) detection in aqueous solution with thiol derivatized fluoresceins. Inorganic Chemistry. 45: 2742-9. PMID 16529499 DOI: 10.1021/ic052083w  1
2006 Goldsmith CR, Lippard SJ. 6-methylpyridyl for pyridyl substitution tunes the properties of fluorescent zinc sensors of the Zinpyr family. Inorganic Chemistry. 45: 555-61. PMID 16411690 DOI: 10.1021/ic051113s  1
2006 Goldsmith CR, Jaworski J, Sheng M, Lippard SJ. Selective labeling of extracellular proteins containing polyhistidine sequences by a fluorescein-nitrilotriacetic acid conjugate. Journal of the American Chemical Society. 128: 418-9. PMID 16402822 DOI: 10.1021/ja0559754  1
2006 Giblin LJ, Chang CJ, Bentley AF, Frederickson C, Lippard SJ, Frederickson CJ. Zinc-secreting Paneth cells studied by ZP fluorescence. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 54: 311-6. PMID 16260591 DOI: 10.1369/jhc.5A6724.2005  1
2005 Nolan EM, Jaworski J, Okamoto K, Hayashi Y, Sheng M, Lippard SJ. QZ1 and QZ2: rapid, reversible quinoline-derivatized fluoresceins for sensing biological Zn(II). Journal of the American Chemical Society. 127: 16812-23. PMID 16316228 DOI: 10.1021/ja052184t  1
2005 Kodanko JJ, Xu D, Song D, Lippard SJ. Iron substitution for sodium in a carboxylate-bridged, heterodinuclear sodium-iron complex. Journal of the American Chemical Society. 127: 16004-5. PMID 16287269 DOI: 10.1021/ja054943d  1
2005 Kodanko JJ, Morys AJ, Lippard SJ. Synthesis of diethynyltriptycene-linked dipyridyl ligands. Organic Letters. 7: 4585-8. PMID 16209485 DOI: 10.1021/ol051700h  1
2005 Lim MH, Lippard SJ. Copper complexes for fluorescence-based NO detection in aqueous solution. Journal of the American Chemical Society. 127: 12170-1. PMID 16131164 DOI: 10.1021/ja053150o  1
2005 Danford AJ, Wang D, Wang Q, Tullius TD, Lippard SJ. Platinum anticancer drug damage enforces a particular rotational setting of DNA in nucleosomes. Proceedings of the National Academy of Sciences of the United States of America. 102: 12311-6. PMID 16116097 DOI: 10.1073/pnas.0506025102  1
2005 Smith RC, Tennyson AG, Lim MH, Lippard SJ. Conjugated polymer-based fluorescence turn-on sensor for nitric oxide. Organic Letters. 7: 3573-5. PMID 16048345 DOI: 10.1021/ol0513903  1
2005 Gherman BF, Lippard SJ, Friesner RA. Substrate hydroxylation in methane monooxygenase: quantitative modeling via mixed quantum mechanics/molecular mechanics techniques. Journal of the American Chemical Society. 127: 1025-37. PMID 15656641 DOI: 10.1021/ja049847b  1
2004 Nolan EM, Lippard SJ. The zinspy family of fluorescent zinc sensors: syntheses and spectroscopic investigations. Inorganic Chemistry. 43: 8310-7. PMID 15606177 DOI: 10.1021/ic048778z  1
2004 Chang CJ, Nolan EM, Jaworski J, Okamoto K, Hayashi Y, Sheng M, Lippard SJ. ZP8, a neuronal zinc sensor with improved dynamic range; imaging zinc in hippocampal slices with two-photon microscopy. Inorganic Chemistry. 43: 6774-9. PMID 15476377 DOI: 10.1021/ic049293d  1
2004 Lim MH, Lippard SJ. Fluorescence-based nitric oxide detection by ruthenium porphyrin fluorophore complexes. Inorganic Chemistry. 43: 6366-70. PMID 15446885 DOI: 10.1021/ic035418n  1
2004 Zhang CX, Chang PV, Lippard SJ. Identification of nuclear proteins that interact with platinum-modified DNA by photoaffinity labeling. Journal of the American Chemical Society. 126: 6536-7. PMID 15161265 DOI: 10.1021/ja049533o  0.84
2004 Chang CJ, Nolan EM, Jaworski J, Burdette SC, Sheng M, Lippard SJ. Bright fluorescent chemosensor platforms for imaging endogenous pools of neuronal zinc. Chemistry & Biology. 11: 203-10. PMID 15123282 DOI: 10.1016/j.chembiol.2004.01.017  1
2004 Hilderbrand SA, Lim MH, Lippard SJ. Dirhodium tetracarboxylate scaffolds as reversible fluorescence-based nitric oxide sensors. Journal of the American Chemical Society. 126: 4972-8. PMID 15080703 DOI: 10.1021/ja038471j  1
2004 Nolan EM, Burdette SC, Harvey JH, Hilderbrand SA, Lippard SJ. Synthesis and characterization of zinc sensors based on a monosubstituted fluorescein platform. Inorganic Chemistry. 43: 2624-35. PMID 15074981 DOI: 10.1021/ic035158+  1
2004 Gherman BF, Baik MH, Lippard SJ, Friesner RA. Dioxygen activation in methane monooxygenase: a theoretical study. Journal of the American Chemical Society. 126: 2978-90. PMID 14995216 DOI: 10.1021/ja036506+  1
2004 Kuzelka J, Mukhopadhyay S, Spingler B, Lippard SJ. Synthesis and characterization of Cu(2)(I,I), Cu(2)(I,II), and Cu(2)(II,II) compounds supported by two phthalazine-based ligands: influence of a hydrophobic pocket. Inorganic Chemistry. 43: 1751-61. PMID 14989668 DOI: 10.1021/ic035009r  1
2004 Chang CJ, Jaworski J, Nolan EM, Sheng M, Lippard SJ. A tautomeric zinc sensor for ratiometric fluorescence imaging: application to nitric oxide-induced release of intracellular zinc. Proceedings of the National Academy of Sciences of the United States of America. 101: 1129-34. PMID 14734801 DOI: 10.1073/pnas.0308079100  1
2003 Baik MH, Friesner RA, Lippard SJ. cis-[Pt(NH3)2(L)]2+/+ (L = Cl, H2O, NH3) binding to purines and CO: does pi-back-donation play a role? Inorganic Chemistry. 42: 8615-7. PMID 14686835 DOI: 10.1021/ic035022b  1
2003 Nolan EM, Lippard SJ. A "turn-on" fluorescent sensor for the selective detection of mercuric ion in aqueous media. Journal of the American Chemical Society. 125: 14270-1. PMID 14624563 DOI: 10.1021/ja037995g  1
2003 Baik MH, Friesner RA, Lippard SJ. Theoretical study of cisplatin binding to purine bases: why does cisplatin prefer guanine over adenine? Journal of the American Chemical Society. 125: 14082-92. PMID 14611245 DOI: 10.1021/ja036960d  1
2003 Kuzelka J, Mukhopadhyay S, Spingler B, Lippard SJ. Modeling features of the non-heme diiron cores in O2-activating enzymes through the synthesis, characterization, and oxidation of 1,8-naphthyridine-based complexes. Inorganic Chemistry. 42: 6447-57. PMID 14514321 DOI: 10.1021/ic0345976  1
2003 Zhang CX, Lippard SJ. New metal complexes as potential therapeutics. Current Opinion in Chemical Biology. 7: 481-9. PMID 12941423  0.84
2003 Baik MH, Newcomb M, Friesner RA, Lippard SJ. Mechanistic studies on the hydroxylation of methane by methane monooxygenase. Chemical Reviews. 103: 2385-419. PMID 12797835 DOI: 10.1021/cr950244f  1
2003 Clark MA, Duffy K, Tibrewala J, Lippard SJ. Synthesis and metal-binding properties of chelating fluorescein derivatives. Organic Letters. 5: 2051-4. PMID 12790526 DOI: 10.1021/ol0344570  1
2003 Guallar V, Baik MH, Lippard SJ, Friesner RA. Peripheral heme substituents control the hydrogen-atom abstraction chemistry in cytochromes P450. Proceedings of the National Academy of Sciences of the United States of America. 100: 6998-7002. PMID 12771375 DOI: 10.1073/pnas.0732000100  1
2003 Wirstam M, Lippard SJ, Friesner RA. Reversible dioxygen binding to hemerythrin. Journal of the American Chemical Society. 125: 3980-7. PMID 12656634 DOI: 10.1021/ja017692r  1
2003 Boerzel H, Koeckert M, Bu W, Spingler B, Lippard SJ. Zinc-bound thiolate-disulfide exchange: a strategy for inhibiting metallo-beta-lactamases. Inorganic Chemistry. 42: 1604-15. PMID 12611529 DOI: 10.1021/ic025624f  1
2002 Baik MH, Gherman BF, Friesner RA, Lippard SJ. Hydroxylation of methane by non-heme diiron enzymes: molecular orbital analysis of C-H bond activation by reactive intermediate Q. Journal of the American Chemical Society. 124: 14608-15. PMID 12465971 DOI: 10.1021/ja026794u  1
2002 Silverman AP, Bu W, Cohen SM, Lippard SJ. 2.4-A crystal structure of the asymmetric platinum complex [Pt(ammine)(cyclohexylamine)]2+ bound to a dodecamer DNA duplex. The Journal of Biological Chemistry. 277: 49743-9. PMID 12377787 DOI: 10.1074/jbc.M206979200  0.92
2002 Zamble DB, Mikata Y, Eng CH, Sandman KE, Lippard SJ. Testis-specific HMG-domain protein alters the responses of cells to cisplatin. Journal of Inorganic Biochemistry. 91: 451-62. PMID 12175937 DOI: 10.1016/S0162-0134(02)00472-5  1
2002 Lee D, DuBois JL, Pierce B, Hedman B, Hodgson KO, Hendrich MP, Lippard SJ. Structural and spectroscopic studies of valence-delocalized diiron(II,III) complexes dupported by carboxylate-only bridging ligands. Inorganic Chemistry. 41: 3172-82. PMID 12054996 DOI: 10.1021/ic011050n  1
2002 Guallar V, Gherman BF, Lippard SJ, Friesner RA. Quantum chemical studies of methane monooxygenase: comparision with P450. Current Opinion in Chemical Biology. 6: 236-42. PMID 12039010 DOI: 10.1016/S1367-5931(02)00310-1  1
2002 Lee D, Lippard SJ. Modeling dioxygen-activating centers in non-heme diiron enzymes: carboxylate shifts in diiron(II) complexes supported by sterically hindered carboxylate ligands. Inorganic Chemistry. 41: 2704-19. PMID 12005495 DOI: 10.1021/ic020186y  1
2002 Bino A, Ardon M, Lee D, Spingler B, Lippard SJ. Synthesis and structure of [Fe(13)O(4)F(24)(OMe)(12)](5-): the first open-shell Keggin ion. Journal of the American Chemical Society. 124: 4578-9. PMID 11971702 DOI: 10.1021/ja025590a  1
2002 Baik MH, Friesner RA, Lippard SJ. Theoretical study on the stability of N-glycosyl bonds: why does N7-platination not promote depurination? Journal of the American Chemical Society. 124: 4495-503. PMID 11960480 DOI: 10.1021/ja017588+  1
2002 Lee D, Pierce B, Krebs C, Hendrich MP, Huynh BH, Lippard SJ. Functional mimic of dioxygen-activating centers in non-heme diiron enzymes: mechanistic implications of paramagnetic intermediates in the reactions between diiron(II) complexes and dioxygen. Journal of the American Chemical Society. 124: 3993-4007. PMID 11942838 DOI: 10.1021/ja012251t  1
2002 Smoukov SK, Kopp DA, Valentine AM, Davydov R, Lippard SJ, Hoffman BM. Product binding to the diiron(III) and mixed-valence diiron centers of methane monooxygenase hydroxylase studied by (1,2)H and (19)F ENDOR spectroscopy. Journal of the American Chemical Society. 124: 2657-63. PMID 11890816 DOI: 10.1021/ja010123z  1
2002 Tshuva EY, Lee D, Bu W, Lippard SJ. Catalytic oxidation by a carboxylate-bridged non-heme diiron complex. Journal of the American Chemical Society. 124: 2416-7. PMID 11890772 DOI: 10.1021/ja017890i  1
2002 Lee D, Lippard SJ. Synthetic analogue of the [Fe(2)(mu-OH)(2)(mu-O(2)CR)](3+) core of soluble methane monooxygenase hydroxylase via synthesis and dioxygen reactivity of carboxylate-bridged diiron(II) complexes. Inorganic Chemistry. 41: 827-37. PMID 11849083 DOI: 10.1021/ic011008s  1
2002 Lee D, Hung PL, Spingler B, Lippard SJ. Sterically hindered carboxylate ligands support water-bridged dimetallic centers that model features of metallohydrolase active sites. Inorganic Chemistry. 41: 521-31. PMID 11825079 DOI: 10.1021/ic0107431  1
2001 He C, DuBois JL, Hedman B, Hodgson KO, Lippard SJ. A Short Copper-Copper Distance in a (μ-1,2-Peroxo)dicopper(II) Complex Having a 1,8-Naphthyridine Unit as an Additional Bridge. Angewandte Chemie (International Ed. in English). 40: 1484-1487. PMID 29712360 DOI: 10.1002/1521-3773(20010417)40:8<1484::AID-ANIE1484>3.0.CO;2-Z  1
2001 Merkx M, Kopp DA, Sazinsky MH, Blazyk JL, Müller J, Lippard SJ. Dioxygen Activation and Methane Hydroxylation by Soluble Methane Monooxygenase: A Tale of Two Irons and Three Proteins. Angewandte Chemie (International Ed. in English). 40: 2782-2807. PMID 29711993 DOI: 10.1002/1521-3773(20010803)40:15<2782::AID-ANIE2782>3.0.CO;2-P  0.56
2001 Lee D, Sorace L, Caneschi A, Lippard SJ. Hydroxo-bridged Cubane-type tetrairon(II) clusters supported by sterically-hindered carboxylate ligands. Inorganic Chemistry. 40: 6774-81. PMID 11735490 DOI: 10.1021/ic010726b  1
2001 Spingler B, Whittington DA, Lippard SJ. 2.4 A crystal structure of an oxaliplatin 1,2-d(GpG) intrastrand cross-link in a DNA dodecamer duplex. Inorganic Chemistry. 40: 5596-602. PMID 11599959 DOI: 10.1021/ic010790t  1
2001 Cohen SM, Lippard SJ. Cisplatin: from DNA damage to cancer chemotherapy. Progress in Nucleic Acid Research and Molecular Biology. 67: 93-130. PMID 11525387  0.92
2001 Wei M, Cohen SM, Silverman AP, Lippard SJ. Effects of spectator ligands on the specific recognition of intrastrand platinum-DNA cross-links by high mobility group box and TATA-binding proteins. The Journal of Biological Chemistry. 276: 38774-80. PMID 11514569 DOI: 10.1074/jbc.M106374200  0.92
2001 Mizoguchi TJ, Kuzelka J, Spingler B, DuBois JL, Davydov RM, Hedman B, Hodgson KO, Lippard SJ. Synthesis and spectroscopic studies of non-heme diiron(III) species with a terminal hydroperoxide ligand: models for hemerythrin. Inorganic Chemistry. 40: 4662-73. PMID 11511213 DOI: 10.1021/ic010076b  1
2001 Burdette SC, Walkup GK, Spingler B, Tsien RY, Lippard SJ. Fluorescent sensors for Zn(2+) based on a fluorescein platform: synthesis, properties and intracellular distribution. Journal of the American Chemical Society. 123: 7831-41. PMID 11493056 DOI: 10.1021/ja010059l  1
2001 Lee D, Lippard SJ. Oxidative N-dealkylation of a carboxylate-bridged diiron(II) precursor complex by reaction with O2 affords the elusive [Fe2(mu-OH)2(mu-O2CR)](3+) core of soluble methane monooxygenase hydroxylase. Journal of the American Chemical Society. 123: 4611-2. PMID 11457252 DOI: 10.1021/ja0100930  1
2001 Gherman BF, Dunietz BD, Whittington DA, Lippard SJ, Friesner RA. Activation of the C-H bond of methane by intermediate Q of methane monooxygenase: a theoretical study. Journal of the American Chemical Society. 123: 3836-7. PMID 11457123 DOI: 10.1021/ja0055108  1
2001 Franz KJ, Doerrer LH, Spingler B, Lippard SJ. Pentacoordinate cobalt(III) thiolate and nitrosyl tropocoronand compounds. Inorganic Chemistry. 40: 3774-80. PMID 11442376 DOI: 10.1021/ic010181l  1
2001 Kaminskaia NV, Spingler B, Lippard SJ. Intermediate in beta-lactam hydrolysis catalyzed by a dinuclear zinc(II) complex: relevance to the mechanism of metallo-beta-lactamase. Journal of the American Chemical Society. 123: 6555-63. PMID 11439042 DOI: 10.1021/ja002699e  1
2001 He C, DuBois JL, Hedman B, Hodgson KO, Lippard SJ. A Short Copper-Copper Distance in a (µ-1,2-Peroxo)dicopper(II) Complex Having a 1,8-Naphthyridine Unit as an Additional Bridge This work was supported by grants from the National Science Foundation and the National Institutes of Health. We thank A. M. Barrios for help in acquiring resonance Raman spectra. X-ray absorption spectroscopic data were measured at SSRL. SSRL is funded by the Department of Energy, Office of Basic Energy Science. The SSRL Structural Molecular Biology Program is supported by the National Institute of Health, National Center for Research Resources, Biomedical Technology Program, and by the Department of Energy, Office of Biological and Environmental Research. Angewandte Chemie (International Ed. in English). 40: 1484-1487. PMID 11317309 DOI: 10.1002/1521-3773(20010417)40:8<1484::AID-ANIE1484>3.0.CO;2-Z  1
2001 Whittington DA, Rosenzweig AC, Frederick CA, Lippard SJ. Xenon and halogenated alkanes track putative substrate binding cavities in the soluble methane monooxygenase hydroxylase. Biochemistry. 40: 3476-82. PMID 11297413 DOI: 10.1021/bi0022487  1
2001 He C, Lippard SJ. Synthesis and electrochemical studies of diiron complexes of 1,8-naphthyridine-based dinucleating ligands to model features of the active sites of non-heme diiron enzymes. Inorganic Chemistry. 40: 1414-20. PMID 11261945  1
2001 Stahl SS, Francisco WA, Merkx M, Klinman JP, Lippard SJ. Oxygen kinetic isotope effects in soluble methane monooxygenase. The Journal of Biological Chemistry. 276: 4549-53. PMID 11073959 DOI: 10.1074/jbc.M008301200  1
2000 Franz KJ, Singh N, Spingler B, Lippard SJ. Aminotroponiminates as ligands for potential metal-based nitric oxide sensors. Inorganic Chemistry. 39: 4081-92. PMID 11198863 DOI: 10.1021/ic000344q  1
2000 He C, Gomez V, Spingler B, Lippard SJ. Monodentate-bridged phosphodiester and sulfate complexes: structural insights into the biological activation of phosphodiesters, sulfate, and sulfate esters. Inorganic Chemistry. 39: 4188-9. PMID 11196909 DOI: 10.1021/ic000391i  1
2000 Kaminskaia NV, He C, Lippard SJ. Reactivity of mu-hydroxodizinc(II) centers in enzymatic catalysis through model studies. Inorganic Chemistry. 39: 3365-73. PMID 11196876  1
2000 Franz KJ, Lippard SJ. Nitrosyl transfer from manganese to iron in tropocoronand complexes. Inorganic Chemistry. 39: 3722-3. PMID 11196841 DOI: 10.1021/ic000360n  1
2000 He C, Lippard SJ. Synthesis and characterization of several dicopper(I) complexes and a spin-delocalized dicopper(I,II) mixed-valence complex using a 1,8-naphthyridine-based dinucleating ligand. Inorganic Chemistry. 39: 5225-31. PMID 11154580  1
2000 Ziegler CJ, Silverman AP, Lippard SJ. High-throughput synthesis and screening of platinum drug candidates. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 5: 774-83. PMID 11129005 DOI: 10.1007/s007750000170  0.68
2000 Burstyn JN, Heiger-Bernays WJ, Cohen SM, Lippard SJ. Formation of cis-diamminedichloroplatinum(II) 1,2-intrastrand cross-links on DNA is flanking-sequence independent. Nucleic Acids Research. 28: 4237-43. PMID 11058123  1
2000 Cohen SM, Mikata Y, He Q, Lippard SJ. HMG-domain protein recognition of cisplatin 1,2-intrastrand d(GpG) cross-links in purine-rich sequence contexts. Biochemistry. 39: 11771-6. PMID 10995245  0.92
2000 Zhang XX, Lippard SJ. Synthesis of PDK, a novel porphyrin-linked dicarboxylate ligand. The Journal of Organic Chemistry. 65: 5298-305. PMID 10993359  0.32
2000 Franz KJ, Singh N, Lippard SJ. Metal-Based NO Sensing by Selective Ligand Dissociation This work was supported by a grant from the National Science Foundation and a fellowship to N.S. from the Undergraduate Research Opportunity Program (MIT). We thank Prof. Roger Tsien for valuable discussions at the inception of this project. Angewandte Chemie (International Ed. in English). 39: 2120-2122. PMID 10941035 DOI: 10.1002/1521-3773(20000616)39:12<2120::AID-ANIE2120>3.0.CO;2-M  1
2000 Cohen SM, Jamieson ER, Lippard SJ. Enhanced binding of the TATA-binding protein to TATA boxes containing flanking cisplatin 1,2-cross-links. Biochemistry. 39: 8259-65. PMID 10889034  0.92
2000 Coufal DE, Blazyk JL, Whittington DA, Wu WW, Rosenzweig AC, Lippard SJ. Sequencing and analysis of the Mmethylococcus capsulatus (Bath) solublemethane monooxygenase genes. European Journal of Biochemistry / Febs. 267: 2174-85. PMID 10759840 DOI: 10.1046/j.1432-1327.2000.01210.x  1
1999 Wilker JJ, Lippard SJ. Methylation of Iron-Sulfur Complexes by Trimethyl Phosphate. Inorganic Chemistry. 38: 3569-3574. PMID 11671106 DOI: 10.1021/ic9808899  1
1999 Ziegler CJ, Sandman KE, Liang CH, Lippard SJ. Toxicity of platinum(II) amino acid (N,O) complexes parallels their binding to DNA as measured in a new solid phase assay involving a fluorescent HMG1 protein construct readout. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 4: 402-11. PMID 10555574  0.68
1999 Valentine AM, LeTadic-Biadatti MH, Toy PH, Newcomb M, Lippard SJ. Oxidation of ultrafast radical clock substrate probes by the soluble methane monooxygenase from Methylococcus capsulatus (Bath). The Journal of Biological Chemistry. 274: 10771-6. PMID 10196150 DOI: 10.1074/jbc.274.16.10771  1
1999 Davydov R, Valentine AM, Komar-Panicucci S, Hoffman BM, Lippard SJ. An EPR study of the dinuclear iron site in the soluble methane monooxygenase from Methylococcus capsulatus (Bath) reduced by one electron at 77 K: the effects of component interactions and the binding of small molecules to the diiron(III) center. Biochemistry. 38: 4188-97. PMID 10194335 DOI: 10.1021/bi982391o  1
1997 Doerrer LH, Bautista MT, Lippard SJ. Tuning of Electronic Properties and Reactivity in Four-Coordinate Cobalt(III) Complexes by the Tetraazamacrocyclic Tropocoronand Ligand. Inorganic Chemistry. 36: 3578-3579. PMID 11670045  1
1997 Wilker JJ, Wetterhahn KE, Lippard SJ. Methyl Transfer to Mercury Thiolates: Effects of Coordination Number and Ligand Dissociation. Inorganic Chemistry. 36: 2079-2083. PMID 11669826  1
1997 Wilker JJ, Lippard SJ. Alkyl Transfer to Metal Thiolates: Kinetics, Active Species Identification, and Relevance to the DNA Methyl Phosphotriester Repair Center of Escherichia coli Ada. Inorganic Chemistry. 36: 969-978. PMID 11669658  1
1997 Rosenzweig AC, Brandstetter H, Whittington DA, Nordlund P, Lippard SJ, Frederick CA. Crystal structures of the methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath): implications for substrate gating and component interactions. Proteins. 29: 141-52. PMID 9329079 DOI: 10.1002/(SICI)1097-0134(199710)29:2<141::AID-PROT2>3.0.CO;2-G  1
1996 Feig AL, Bautista MT, Lippard SJ. A Carboxylate-Bridged Non-Heme Diiron Dinitrosyl Complex. Inorganic Chemistry. 35: 6892-6898. PMID 11666858  1
1996 Jaynes BS, Doerrer LH, Liu S, Lippard SJ. Synthesis, Tuning of the Stereochemistry, and Physical Properties of Cobalt(II) Tropocoronand Complexes. Inorganic Chemistry. 35: 6630. PMID 11666816  1
1996 Feig AL, Becker M, Schindler S, van Eldik R, Lippard SJ. Mechanistic Studies of the Formation and Decay of Diiron(III) Peroxo Complexes in the Reaction of Diiron(II) Precursors with Dioxygen. Inorganic Chemistry. 35: 2590-2601. PMID 11666474  1
1995 Rosenzweig AC, Nordlund P, Takahara PM, Frederick CA, Lippard SJ. Geometry of the soluble methane monooxygenase catalytic diiron center in two oxidation states. Chemistry & Biology. 2: 409-18. PMID 9432288 DOI: 10.1016/1074-5521(95)90222-8  1
1995 Rosenzweig AC, Nordlund P, Takahara PM, Frederick CA, Lippard SJ. Geometry of the soluble methane monooxygenase catalytic diiron center in two oxidation states. Chemistry & Biology. 2: 409-18. PMID 9383443  1
1995 Takahara PM, Rosenzweig AC, Frederick CA, Lippard SJ. Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin. Nature. 377: 649-52. PMID 7566180 DOI: 10.1038/377649a0  1
1994 Bender CJ, Rosenzweig AC, Lippard SJ, Peisach J. Nuclear hyperfine coupling of nitrogen in the coordination sphere of the diiron center of methane monooxygenase hydroxylase. The Journal of Biological Chemistry. 269: 15993-8. PMID 8206895  1
1993 Rosenzweig AC, Frederick CA, Lippard SJ, Nordlund P. Crystal structure of a bacterial non-haem iron hydroxylase that catalyses the biological oxidation of methane. Nature. 366: 537-43. PMID 8255292 DOI: 10.1038/366537a0  1
1992 Rosenzweig AC, Frederick CA, Lippard SJ. Crystallization and preliminary X-ray analysis of the methane monooxygenase hydroxylase protein from Methylococcus capsulatus (Bath). Journal of Molecular Biology. 227: 583-5. PMID 1404375 DOI: 10.1016/0022-2836(92)90913-5  1
1992 Comess KM, Burstyn JN, Essigmann JM, Lippard SJ. Replication inhibition and translesion synthesis on templates containing site-specifically placed cis-diamminedichloroplatinum(II) DNA adducts. Biochemistry. 31: 3975-90. PMID 1314653  1
1991 Hollis LS, Sundquist WI, Burstyn JN, Heiger-Bernays WJ, Bellon SF, Ahmed KJ, Amundsen AR, Stern EW, Lippard SJ. Mechanistic studies of a novel class of trisubstituted platinum(II) antitumor agents. Cancer Research. 51: 1866-75. PMID 2004370  1
1990 Coll M, Sherman SE, Gibson D, Lippard SJ, Wang AH. Molecular structure of the complex formed between the anticancer drug cisplatin and d(pGpG): C222(1) crystal form. Journal of Biomolecular Structure & Dynamics. 8: 315-30. PMID 2268406 DOI: 10.1080/07391102.1990.10507808  1
1987 O'Halloran TV, Lippard SJ, Richmond TJ, Klug A. Multiple heavy-atom reagents for macromolecular X-ray structure determination. Application to the nucleosome core particle. Journal of Molecular Biology. 194: 705-12. PMID 3656403 DOI: 10.1016/0022-2836(87)90248-8  1
1986 Armstrong WH, Spool A, Papaefthymiou GC, Frankel RB, Lippard SJ. Correction. Assembly and characterization of an accurate model for the dron center in hemerythrin. Journal of the American Chemical Society. 108: 557. PMID 22175507 DOI: 10.1021/ja00263a600  0.6
1986 Bowler BE, Lippard SJ. Modulation of platinum antitumor drug binding to DNA by linked and free intercalators. Biochemistry. 25: 3031-8. PMID 3718938  1
1985 Sherman SE, Gibson D, Wang AH, Lippard SJ. X-ray structure of the major adduct of the anticancer drug cisplatin with DNA: cis-[Pt(NH3)2(d(pGpG))]. Science (New York, N.Y.). 230: 412-7. PMID 4048939  1
1983 Mascharak PK, Sugiura Y, Kuwahara J, Suzuki T, Lippard SJ. Alteration and activation of sequence-specific cleavage of DNA by bleomycin in the presence of the antitumor drug cis-diamminedichloroplatinum(II). Proceedings of the National Academy of Sciences of the United States of America. 80: 6795-8. PMID 6196777  0.32
1982 Ushay HM, Santella RM, Caradonna JP, Grunberger D, Lippard SJ. Binding of [(dien)PtCl] Cl to poly(dG-dC)-poly(dG-dC) facilitates the B goes to Z conformational transition. Nucleic Acids Research. 10: 3573-88. PMID 7201636 DOI: 10.1093/nar/10.11.3573  1
1982 Tullius TD, Lippard SJ. Ethidium bromide changes the nuclease-sensitive DNA binding sites of the antitumor drug cis-diamminedichloroplatinum(II). Proceedings of the National Academy of Sciences of the United States of America. 79: 3489-92. PMID 6954494  1
1981 Ushay HM, Tullius TD, Lippard SJ. Inhibition of the BamHI cleavage and unwinding of pBR322 deoxyribonucleic acid by the antitumor drug cis-dichlorodiammineplatinum(II). Biochemistry. 20: 3744-8. PMID 6268142  1
1979 Barton JK, Lippard SJ. Cooperative binding of a platinum metallointercalation reagent to poly(A).poly(U). Biochemistry. 18: 2661-8. PMID 444486  1
1979 Cohen GL, Bauer WR, Barton JK, Lippard SJ. Binding of cis- and trans-dichlorodiammineplatinum(II) to DNA: evidence for unwinding and shortening of the double helix. Science (New York, N.Y.). 203: 1014-6. PMID 370979  1
1978 Barton JK, Lippard SJ. A crystalline platinum blue: its molecular structure, chemical reactivity, and possible relevance to the mode of action of antitumor platinum drugs. Annals of the New York Academy of Sciences. 313: 686-7. PMID 216295  1
1975 Jennette KW, Lippard SJ, Ucko DA. 13C magnetic resonance investigation of mercury (II) binding to nucleosides and thiolated nucleosides in dimethyl sulfoxide. Biochimica Et Biophysica Acta. 402: 403-12. PMID 1164524 DOI: 10.1016/0005-2787(75)90275-0  1
1975 Bond PJ, Langridge R, Jennette KW, Lippard SJ. X-ray fiber diffraction evidence for neighbor exclusion binding of a platinum metallointercalation reagent to DNA. Proceedings of the National Academy of Sciences of the United States of America. 72: 4825-9. PMID 1061071  1
1974 Jennette KW, Lippard SJ, Vassiliades GA, Bauer WR. Metallointercalation reagents. 2-hydroxyethanethiolato(2,2',2'-terpyridine)-platinum(II) monocation binds strongly to DNA by intercalation. Proceedings of the National Academy of Sciences of the United States of America. 71: 3839-43. PMID 4530265  1
1964 Cotton FA, Curtis NF, Harris CB, Johnson BF, Lippard SJ, Mague JT, Robinson WR, Wood JS. Mononuclear and Polynuclear Chemistry of Rhenium (III): Its Pronounced Homophilicity. Science (New York, N.Y.). 145: 1305-7. PMID 17802015 DOI: 10.1126/science.145.3638.1305  1
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