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Stephen James Lippard - Publications

Affiliations: 
1966-1983 Columbia University, New York, NY 
 1983- Massachusetts Institute of Technology, Cambridge, MA, United States 
Area:
bioinorganic chemistry
Website:
http://lippardlab.mit.edu/stephen-j-lippard
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Year Citation  Score
2020 Kong YW, Dreaden EC, Morandell S, Zhou W, Dhara SS, Sriram G, Lam FC, Patterson JC, Quadir M, Dinh A, Shopsowitz KE, Varmeh S, Yilmaz ÖH, Lippard SJ, Reinhardt HC, et al. Enhancing chemotherapy response through augmented synthetic lethality by co-targeting nucleotide excision repair and cell-cycle checkpoints. Nature Communications. 11: 4124. PMID 32807787 DOI: 10.1038/S41467-020-17958-Z  0.375
2020 Fadzen CM, Wolfe JM, Zhou W, Cho CF, von Spreckelsen N, Hutchinson KT, Lee YC, Chiocca EA, Lawler S, Yilmaz ÖH, Lippard SJ, Pentelute BL. A Platinum(IV) Prodrug - Perfluoroaryl Macrocyclic Peptide Conjugate Enhances Platinum Uptake in the Brain. Journal of Medicinal Chemistry. PMID 32410451 DOI: 10.1021/Acs.Jmedchem.0C00022  0.355
2020 Zastrow ML, Huang Z, Lippard SJ. HaloTag-based hybrid targetable and ratiometric sensors for intracellular zinc. Acs Chemical Biology. PMID 31917534 DOI: 10.1021/Acschembio.9B00872  0.724
2019 Almaqwashi AA, Zhou W, Naufer MN, Riddell IA, Yilmaz ÖH, Lippard SJ, Williams MC. DNA intercalation facilitates efficient DNA-targeted covalent binding of phenanthriplatin. Journal of the American Chemical Society. PMID 30599508 DOI: 10.1021/Jacs.8B10252  0.427
2019 Steinhuebel DP, Lippard SJ. Synthetic and Structural Studies of Titanium Aminotroponiminate Complexes. Inorganic Chemistry. 38: 6225-6233. PMID 11671337 DOI: 10.1021/Ic9909072  0.397
2019 LeCloux DD, Davydov R, Lippard SJ. Mixed-Valence Cu(I)-Cu(II) and Heterodimetallic Cu(I)-M(II) Bis(carboxylate-bridged) Complexes: Structural, Electrochemical, and Spectroscopic Investigations. Inorganic Chemistry. 37: 6814-6826. PMID 11670817 DOI: 10.1021/Ic980763B  0.318
2019 Mizoguchi TJ, Lippard SJ. (&mgr;-Oxo)bis(&mgr;-carboxylato)bis(2,2'-bipyridyl)bis(X)diiron(III) Complexes, X = NCS(-), NCSe(-), and N(3)(-): Synthetic Models of Pseudohalide Derivatives of Carboxylate-Bridged Diiron Proteins. Inorganic Chemistry. 36: 4526-4533. PMID 11670117 DOI: 10.1021/Ic970397G  0.36
2018 Richardson CER, Nolan EM, Shoulders MD, Lippard SJ. A sensitive, non-radioactive assay for Zn(II) uptake into metazoan cells. Biochemistry. PMID 30381945 DOI: 10.1021/Acs.Biochem.8B01043  0.745
2018 Hucke A, Park GY, Bauer OB, Beyer G, Köppen C, Zeeh D, Wehe CA, Sperling M, Schröter R, Kantauskaitè M, Hagos Y, Karst U, Lippard SJ, Ciarimboli G. Interaction of the New Monofunctional Anticancer Agent Phenanthriplatin With Transporters for Organic Cations. Frontiers in Chemistry. 6: 180. PMID 29888219 DOI: 10.3389/Fchem.2018.00180  0.53
2018 Zhou W, Almeqdadi M, Xifaras ME, Riddell IA, Yilmaz ÖH, Lippard SJ. The effect of geometric isomerism on the anticancer activity of the monofunctional platinum complex trans-[Pt(NH)(phenanthridine)Cl]NO. Chemical Communications (Cambridge, England). PMID 29484327 DOI: 10.1039/C8Cc00393A  0.451
2018 Goldberg JM, Wang F, Sessler CD, Vogler NW, Zhang DY, Loucks WH, Tzounopoulos T, Lippard SJ. Photoactivatable Sensors for Detecting Mobile Zinc. Journal of the American Chemical Society. PMID 29384658 DOI: 10.1021/Jacs.7B12766  0.328
2018 Richardson CER, Cunden LS, Butty VL, Nolan EM, Lippard SJ, Shoulders MD. A Method for Selective Depletion of Zn(II) Ions from Complex Biological Media and Evaluation of Cellular Consequences of Zn(II) Deficiency. Journal of the American Chemical Society. PMID 29334734 DOI: 10.1021/Jacs.7B12897  0.75
2017 Loas A, Lippard SJ. Direct ratiometric detection of nitric oxide with Cu(II)-based fluorescent probes Journal of Materials Chemistry B. 5: 8929-8933. PMID 32264119 DOI: 10.1039/C7Tb02666H  0.309
2017 Wang F, Becker S, Minier MA, Loas A, Jackson MN, Lippard SJ. Tuning the Diiron Core Geometry in Carboxylate-Bridged Macrocyclic Model Complexes Affects Their Redox Properties and Supports Oxidation Chemistry. Inorganic Chemistry. PMID 28872846 DOI: 10.1021/Acs.Inorgchem.7B01418  0.469
2017 Bruno PM, Liu Y, Park GY, Murai J, Koch CE, Eisen TJ, Pritchard JR, Pommier Y, Lippard SJ, Hemann MT. A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress. Nature Medicine. PMID 28263311 DOI: 10.1038/Nm.4291  0.533
2016 Zheng YR, Suntharalingam K, Bruno PM, Lin W, Wang W, Hemann MT, Lippard SJ. Mechanistic Studies of the Anticancer Activity of An Octahedral Hexanuclear Pt(II) Cage. Inorganica Chimica Acta. 452: 125-129. PMID 27818526 DOI: 10.1016/J.Ica.2016.03.021  0.658
2016 Riddell IA, Agama K, Park GY, Pommier Y, Lippard SJ. Phenanthriplatin Acts as a Covalent Poison of Topoisomerase II Cleavage Complexes. Acs Chemical Biology. PMID 27648475 DOI: 10.1021/Acschembio.6B00565  0.585
2016 Patra M, Awuah SG, Lippard SJ. Chemical approach to positional isomers of glucose-platinum conjugates reveals specific cancer targeting through glucose-transporter mediated uptake in vitro and in vivo. Journal of the American Chemical Society. PMID 27570149 DOI: 10.1021/Jacs.6B06937  0.498
2016 Riddell IA, Johnstone TC, Park GY, Lippard SJ. Nucleotide Binding Preference of the Monofunctional Platinum Anticancer-Agent Phenanthriplatin. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27111128 DOI: 10.1002/Chem.201600236  0.594
2016 Barandov A, Bartelle BB, Gonzalez BA, White WL, Lippard SJ, Jasanoff A. Membrane-permeable Mn(III) complexes for molecular MRI of intracellular targets. Journal of the American Chemical Society. PMID 27088782 DOI: 10.1021/Jacs.5B13337  0.31
2016 Kim S, Minier MA, Loas A, Becker S, Wang F, Lippard SJ. Addition to "Achieving Reversible Sensing of Nitroxyl by Tuning the Ligand Environment of Azamacrocyclic Copper(II) Complexes". Journal of the American Chemical Society. PMID 26977776 DOI: 10.1021/jacs.6b01932  0.32
2016 Zastrow ML, Radford RJ, Chyan W, Anderson CT, Zhang DY, Loas A, Tzounopoulos T, Lippard SJ. Reaction-Based Probes for Imaging Mobile Zinc in Live Cells and Tissues. Acs Sensors. 1: 32-39. PMID 26878065 DOI: 10.1021/Acssensors.5B00022  0.743
2016 Johnstone TC, Suntharalingam K, Lippard SJ. The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs. Chemical Reviews. PMID 26865551 DOI: 10.1021/Acs.Chemrev.5B00597  0.644
2016 Kim S, Minier MA, Loas A, Becker S, Wang F, Lippard SJ. Achieving Reversible Sensing of Nitroxyl (HNO) by Tuning the Ligand Environment of Azamacrocyclic Copper(II) Com-plexes. Journal of the American Chemical Society. PMID 26836121 DOI: 10.1021/Jacs.5B12825  0.405
2016 Patra M, Johnstone TC, Suntharalingam K, Lippard SJ. A Potent Glucose-Platinum Conjugate Exploits Glucose Transporters and Preferentially Accumulates in Cancer Cells. Angewandte Chemie (International Ed. in English). PMID 26749149 DOI: 10.1002/Anie.201510551  0.669
2016 Zheng YR, Suntharalingam K, Bruno PM, Lin W, Wang W, Hemann MT, Lippard SJ. Mechanistic studies of the anticancer activity of an octahedral hexanuclear Pt(II) cage Inorganica Chimica Acta. 452: 125-129. DOI: 10.1016/j.ica.2016.03.021  0.626
2015 Loas A, Radford RJ, Deliz Liang A, Lippard SJ. Solid-phase synthesis provides a modular, lysine-based platform for fluorescent discrimination of nitroxyl and biological thiols. Chemical Science. 6: 4131-4140. PMID 28717469 DOI: 10.1039/C5Sc00880H  0.338
2015 Rivera-Fuentes P, Lippard SJ. Metal-Based Optical Probes for Live Cell Imaging of Nitroxyl (HNO). Accounts of Chemical Research. PMID 26550842 DOI: 10.1021/Acs.Accounts.5B00388  0.672
2015 Karlin KD, Lippard SJ, Valentine JS, Burrows CJ. Solving 21st Century Problems in Biological Inorganic Chemistry Using Synthetic Models. Accounts of Chemical Research. 48: 2659-60. PMID 26481328 DOI: 10.1021/Acs.Accounts.5B00447  0.649
2015 Minier MA, Lippard SJ. (19)F NMR study of ligand dynamics in carboxylate-bridged diiron(ii) complexes supported by a macrocyclic ligand. Dalton Transactions (Cambridge, England : 2003). 44: 18111-21. PMID 26418547 DOI: 10.1039/C5Dt02138C  0.387
2015 Wang W, Liang AD, Lippard SJ. Coupling Oxygen Consumption with Hydrocarbon Oxidation in Bacterial Multicomponent Monooxygenases. Accounts of Chemical Research. PMID 26293615 DOI: 10.1021/Acs.Accounts.5B00312  0.333
2015 Hopmann KH, Conradie J, Tangen E, Tonzetich ZJ, Lippard SJ, Ghosh A. Singlet-Triplet Gaps of Cobalt Nitrosyls: Insights from Tropocoronand Complexes. Inorganic Chemistry. 54: 7362-7. PMID 26203786 DOI: 10.1021/Acs.Inorgchem.5B00901  0.723
2015 Anderson CT, Radford RJ, Zastrow ML, Zhang DY, Apfel UP, Lippard SJ, Tzounopoulos T. Modulation of extrasynaptic NMDA receptors by synaptic and tonic zinc. Proceedings of the National Academy of Sciences of the United States of America. 112: E2705-14. PMID 25947151 DOI: 10.1073/Pnas.1503348112  0.711
2015 Rivera-Fuentes P, Wrobel AT, Zastrow ML, Khan M, Georgiou J, Luyben TT, Roder JC, Okamoto K, Lippard SJ. A Far-Red Emitting Probe for Unambiguous Detection of Mobile Zinc in Acidic Vesicles and Deep Tissue. Chemical Science (Royal Society of Chemistry : 2010). 6: 1944-1948. PMID 25815162 DOI: 10.1039/C4Sc03388D  0.767
2015 Sazinsky MH, Lippard SJ. Methane monooxygenase: functionalizing methane at iron and copper. Metal Ions in Life Sciences. 15: 205-56. PMID 25707469 DOI: 10.1007/978-3-319-12415-5_6  0.318
2015 Suntharalingam K, Awuah SG, Bruno PM, Johnstone TC, Wang F, Lin W, Zheng YR, Page JE, Hemann MT, Lippard SJ. Necroptosis-inducing rhenium(V) oxo complexes. Journal of the American Chemical Society. 137: 2967-74. PMID 25698398 DOI: 10.1021/Ja511978Y  0.659
2015 Johnstone TC, Suntharalingam K, Lippard SJ. Third row transition metals for the treatment of cancer. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 373. PMID 25666060 DOI: 10.1098/Rsta.2014.0185  0.64
2015 Zheng YR, Suntharalingam K, Johnstone TC, Lippard SJ. Encapsulation of Pt(IV) Prodrugs within a Pt(II) Cage for Drug Delivery. Chemical Science (Royal Society of Chemistry : 2010). 6: 1189-1193. PMID 25621144 DOI: 10.1039/C4Sc01892C  0.652
2015 Kozhukh J, Minier MA, Lippard SJ. Synthesis and characterization of mononuclear, pseudotetrahedral cobalt(III) compounds. Inorganic Chemistry. 54: 418-24. PMID 25531129 DOI: 10.1021/Ic5009279  0.332
2015 Johnstone TC, Lippard SJ. Improvements in the Synthesis and Understanding of the Iodo-bridged Intermediate en Route to the Pt(IV) Prodrug Satraplatin. Inorganica Chimica Acta. 424: 254-259. PMID 25435590 DOI: 10.1016/J.Ica.2014.08.047  0.333
2015 Johnstone TC, Alexander SM, Wilson JJ, Lippard SJ. Oxidative halogenation of cisplatin and carboplatin: synthesis, spectroscopy, and crystal and molecular structures of Pt(IV) prodrugs. Dalton Transactions (Cambridge, England : 2003). 44: 119-29. PMID 25367395 DOI: 10.1039/C4Dt02627F  0.327
2014 Victor E, Kim S, Lippard SJ. Synthesis of bis(imidazole) metal complexes and their use in rapid NO detection and quantification devices. Inorganic Chemistry. 53: 12809-21. PMID 25419858 DOI: 10.1021/Ic501765G  0.359
2014 Suntharalingam K, Lin W, Johnstone TC, Bruno PM, Zheng YR, Hemann MT, Lippard SJ. A breast cancer stem cell-selective, mammospheres-potent osmium(VI) nitrido complex. Journal of the American Chemical Society. 136: 14413-6. PMID 25247635 DOI: 10.1021/Ja508808V  0.612
2014 Jiang Y, Hayashi T, Matsumura H, Do LH, Majumdar A, Lippard SJ, Moënne-Loccoz P. Light-induced N₂O production from a non-heme iron-nitrosyl dimer. Journal of the American Chemical Society. 136: 12524-7. PMID 25158917 DOI: 10.1021/Ja504343T  0.789
2014 Gregory MT, Park GY, Johnstone TC, Lee YS, Yang W, Lippard SJ. Structural and mechanistic studies of polymerase η bypass of phenanthriplatin DNA damage. Proceedings of the National Academy of Sciences of the United States of America. 111: 9133-8. PMID 24927576 DOI: 10.1073/Pnas.1405739111  0.573
2014 Zheng YR, Suntharalingam K, Johnstone TC, Yoo H, Lin W, Brooks JG, Lippard SJ. Pt(IV) prodrugs designed to bind non-covalently to human serum albumin for drug delivery. Journal of the American Chemical Society. 136: 8790-8. PMID 24902769 DOI: 10.1021/Ja5038269  0.609
2014 Victor E, Lippard SJ. A tetranitrosyl [4Fe-4S] cluster forms en route to Roussin's black anion: nitric oxide reactivity of [Fe4S4(LS3)L'](2-). Inorganic Chemistry. 53: 5311-20. PMID 24773390 DOI: 10.1021/Ic500586G  0.343
2014 Minier MA, Lippard SJ. Conversion Between Doubly and Triply Carboxylate-Bridged Di(ethylzinc) Complexes and Formation of the (μ-Oxo)tetrazinc Carboxylate [Zn4O(Ar(Tol)CO2)6]. Organometallics. 33: 1462-1466. PMID 24761049 DOI: 10.1021/Om5000503  0.344
2014 Khan M, Goldsmith CR, Huang Z, Georgiou J, Luyben TT, Roder JC, Lippard SJ, Okamoto K. Two-photon imaging of Zn2+ dynamics in mossy fiber boutons of adult hippocampal slices. Proceedings of the National Academy of Sciences of the United States of America. 111: 6786-91. PMID 24757053 DOI: 10.1073/Pnas.1405154111  0.645
2014 Rivera-Fuentes P, Lippard SJ. SpiroZin1: a reversible and pH-Insensitive, reaction-based, red-fluorescent probe for imaging biological mobile zinc. Chemmedchem. 9: 1238-43. PMID 24616292 DOI: 10.1002/Cmdc.201400014  0.662
2014 Wrobel AT, Johnstone TC, Deliz Liang A, Lippard SJ, Rivera-Fuentes P. A fast and selective near-infrared fluorescent sensor for multicolor imaging of biological nitroxyl (HNO). Journal of the American Chemical Society. 136: 4697-705. PMID 24564324 DOI: 10.1021/Ja500315X  0.664
2014 Johnstone TC, Lippard SJ. Reinterpretation of the vibrational spectroscopy of the medicinal bioinorganic synthon c,c,t-[Pt(NH3)2Cl2(OH)2]. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 19: 667-74. PMID 24515615 DOI: 10.1007/S00775-014-1109-6  0.3
2014 Suntharalingam K, Wilson JJ, Lin W, Lippard SJ. A dual-targeting, p53-independent, apoptosis-inducing platinum(II) anticancer complex, [Pt(BDI(QQ))]Cl. Metallomics : Integrated Biometal Science. 6: 437-43. PMID 24514456 DOI: 10.1039/C3Mt00364G  0.632
2014 Wang W, Lippard SJ. Diiron oxidation state control of substrate access to the active site of soluble methane monooxygenase mediated by the regulatory component. Journal of the American Chemical Society. 136: 2244-7. PMID 24476336 DOI: 10.1021/Ja412351B  0.335
2014 Suntharalingam K, Song Y, Lippard SJ. Conjugation of vitamin E analog α-TOS to Pt(IV) complexes for dual-targeting anticancer therapy. Chemical Communications (Cambridge, England). 50: 2465-8. PMID 24452361 DOI: 10.1039/C3Cc48740G  0.637
2014 Johnstone TC, Lippard SJ. The chiral potential of phenanthriplatin and its influence on guanine binding. Journal of the American Chemical Society. 136: 2126-34. PMID 24417436 DOI: 10.1021/Ja4125115  0.365
2014 Johnstone TC, Park GY, Lippard SJ. Understanding and improving platinum anticancer drugs--phenanthriplatin. Anticancer Research. 34: 471-6. PMID 24403503  0.526
2014 Johnstone TC, Alexander SM, Lin W, Lippard SJ. Effects of monofunctional platinum agents on bacterial growth: a retrospective study. Journal of the American Chemical Society. 136: 116-8. PMID 24364388 DOI: 10.1021/Ja411742C  0.307
2014 Majumdar A, Apfel UP, Jiang Y, Moënne-Loccoz P, Lippard SJ. Versatile reactivity of a solvent-coordinated diiron(II) compound: synthesis and dioxygen reactivity of a mixed-valent Fe(II)Fe(III) species. Inorganic Chemistry. 53: 167-81. PMID 24359397 DOI: 10.1021/Ic4019585  0.8
2014 Chyan W, Zhang DY, Lippard SJ, Radford RJ. Reaction-based fluorescent sensor for investigating mobile Zn2+ in mitochondria of healthy versus cancerous prostate cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 143-8. PMID 24335702 DOI: 10.1073/Pnas.1310583110  0.328
2014 Wilson JJ, Lippard SJ. Synthetic methods for the preparation of platinum anticancer complexes. Chemical Reviews. 114: 4470-95. PMID 24283498 DOI: 10.1021/Cr4004314  0.362
2014 Victor E, Minier MA, Lippard SJ. Synthesis and characterization of a linear dinitrosyl-triiron complex European Journal of Inorganic Chemistry. 2014: 5640-5645. DOI: 10.1002/Ejic.201402543  0.386
2013 Wilson JJ, Lippard SJ. Oxidative Reactivity and Cytotoxic Properties of a Platinum(II) Complex Prepared by Outer-Sphere Amide Bond Coupling. Polyhedron. 58: 71-78. PMID 24489429 DOI: 10.1016/J.Poly.2012.07.097  0.377
2013 Majumdar A, Lippard SJ. Non-heme mononitrosyldiiron complexes: importance of iron oxidation state in controlling the nature of the nitrosylated products. Inorganic Chemistry. 52: 13292-4. PMID 24246021 DOI: 10.1021/Ic4019508  0.742
2013 Wisnovsky SP, Wilson JJ, Radford RJ, Pereira MP, Chan MR, Laposa RR, Lippard SJ, Kelley SO. Targeting mitochondrial DNA with a platinum-based anticancer agent. Chemistry & Biology. 20: 1323-8. PMID 24183971 DOI: 10.1016/J.Chembiol.2013.08.010  0.484
2013 Xu X, Xie K, Zhang XQ, Pridgen EM, Park GY, Cui DS, Shi J, Wu J, Kantoff PW, Lippard SJ, Langer R, Walker GC, Farokhzad OC. Enhancing tumor cell response to chemotherapy through nanoparticle-mediated codelivery of siRNA and cisplatin prodrug. Proceedings of the National Academy of Sciences of the United States of America. 110: 18638-43. PMID 24167294 DOI: 10.1073/Pnas.1303958110  0.533
2013 Chung CY, Khurana V, Auluck PK, Tardiff DF, Mazzulli JR, Soldner F, Baru V, Lou Y, Freyzon Y, Cho S, Mungenast AE, Muffat J, Mitalipova M, Pluth MD, Jui NT, ... ... Lippard SJ, et al. Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons. Science (New York, N.Y.). 342: 983-7. PMID 24158904 DOI: 10.1126/Science.1245296  0.586
2013 Ghosh M, van den Akker NM, Wijnands KA, Poeze M, Weber C, McQuade LE, Pluth MD, Lippard SJ, Post MJ, Molin DG, van Zandvoort MA. Specific visualization of nitric oxide in the vasculature with two-photon microscopy using a copper based fluorescent probe. Plos One. 8: e75331. PMID 24086509 DOI: 10.1371/Journal.Pone.0075331  0.552
2013 Suntharalingam K, Johnstone TC, Bruno PM, Lin W, Hemann MT, Lippard SJ. Bidentate ligands on osmium(VI) nitrido complexes control intracellular targeting and cell death pathways. Journal of the American Chemical Society. 135: 14060-3. PMID 24041161 DOI: 10.1021/Ja4075375  0.639
2013 Song Y, Suntharalingam K, Yeung JS, Royzen M, Lippard SJ. Synthesis and characterization of Pt(IV) fluorescein conjugates to investigate Pt(IV) intracellular transformations. Bioconjugate Chemistry. 24: 1733-40. PMID 23957697 DOI: 10.1021/Bc400281A  0.664
2013 Kellinger MW, Park GY, Chong J, Lippard SJ, Wang D. Effect of a monofunctional phenanthriplatin-DNA adduct on RNA polymerase II transcriptional fidelity and translesion synthesis. Journal of the American Chemical Society. 135: 13054-61. PMID 23927577 DOI: 10.1021/Ja405475Y  0.58
2013 Johnstone TC, Lippard SJ. The effect of ligand lipophilicity on the nanoparticle encapsulation of Pt(IV) prodrugs. Inorganic Chemistry. 52: 9915-20. PMID 23859129 DOI: 10.1021/Ic4010642  0.311
2013 Johnstone TC, Wilson JJ, Lippard SJ. Monofunctional and higher-valent platinum anticancer agents. Inorganic Chemistry. 52: 12234-49. PMID 23738524 DOI: 10.1021/Ic400538C  0.313
2013 Li Y, Myae Soe CM, Wilson JJ, Tuang SL, Apfel UP, Lippard SJ. Triptycene-based Bis(benzimidazole) Carboxylate-Bridged Biomimetic Diiron(II) Complexes. European Journal of Inorganic Chemistry. 2013: 2011-2019. PMID 23585728 DOI: 10.1002/Ejic.201201387  0.38
2013 Lu TT, Lee SJ, Apfel UP, Lippard SJ. Aging-associated enzyme human clock-1: substrate-mediated reduction of the diiron center for 5-demethoxyubiquinone hydroxylation. Biochemistry. 52: 2236-44. PMID 23445365 DOI: 10.1021/Bi301674P  0.302
2013 Lee SJ, McCormick MS, Lippard SJ, Cho US. Control of substrate access to the active site in methane monooxygenase. Nature. 494: 380-4. PMID 23395959 DOI: 10.1038/Nature11880  0.311
2013 Blakemore LJ, Tomat E, Lippard SJ, Trombley PQ. Zinc released from olfactory bulb glomeruli by patterned electrical stimulation of the olfactory nerve. Metallomics : Integrated Biometal Science. 5: 208-13. PMID 23392381 DOI: 10.1039/C3Mt20158A  0.608
2013 Hope JM, Wilson JJ, Lippard SJ. Photoluminescent DNA binding and cytotoxic activity of a platinum(II) complex bearing a tetradentate β-diketiminate ligand. Dalton Transactions (Cambridge, England : 2003). 42: 3176-80. PMID 23143731 DOI: 10.1039/C2Dt32462H  0.358
2013 Royzen M, Wilson JJ, Lippard SJ. Physical and structural properties of [Cu(BOT1)Cl]Cl, a fluorescent imaging probe for HNO. Journal of Inorganic Biochemistry. 118: 162-70. PMID 23102502 DOI: 10.1016/J.Jinorgbio.2012.08.025  0.334
2012 Pluth MD, Lippard SJ. Reversible binding of nitric oxide to an Fe(III) complex of a tetra-amido macrocycle. Chemical Communications (Cambridge, England). 48: 11981-3. PMID 23133836 DOI: 10.1039/C2Cc37221E  0.628
2012 Sartoretto JL, Kalwa H, Shiroto T, Sartoretto SM, Pluth MD, Lippard SJ, Michel T. Role of Ca2+ in the control of H2O2-modulated phosphorylation pathways leading to eNOS activation in cardiac myocytes. Plos One. 7: e44627. PMID 22970272 DOI: 10.1371/Journal.Pone.0044627  0.533
2012 Wilson JJ, Lippard SJ. Acetate-bridged platinum(III) complexes derived from cisplatin. Inorganic Chemistry. 51: 9852-64. PMID 22946515 DOI: 10.1021/Ic301289J  0.382
2012 Kozhukh J, Lippard SJ. Variable nitric oxide reactivity of tropocoronand cobalt(III) nitrite complexes as a function of the polymethylene linker chain length. Inorganic Chemistry. 51: 9416-22. PMID 22897687 DOI: 10.1021/Ic3012266  0.347
2012 Wilson JJ, Lippard SJ. Modulation of Ligand Fluorescence by the Pt(II)/Pt(IV) Redox Couple. Inorganica Chimica Acta. 389: 77-84. PMID 22837584 DOI: 10.1016/J.Ica.2011.12.034  0.37
2012 Park GY, Wilson JJ, Song Y, Lippard SJ. Phenanthriplatin, a monofunctional DNA-binding platinum anticancer drug candidate with unusual potency and cellular activity profile. Proceedings of the National Academy of Sciences of the United States of America. 109: 11987-92. PMID 22773807 DOI: 10.1073/Pnas.1207670109  0.616
2012 Li Y, Wilson JJ, Do LH, Apfel UP, Lippard SJ. A C2-symmetric, basic Fe(III) carboxylate complex derived from a novel triptycene-based chelating carboxylate ligand. Dalton Transactions (Cambridge, England : 2003). 41: 9272-5. PMID 22751622 DOI: 10.1039/C2Dt31260C  0.645
2012 Kozhukh J, Lippard SJ. Influence of tetraazamacrocyclic ligands on the nitric oxide reactivity of their cobalt(II) complexes. Journal of the American Chemical Society. 134: 11120-3. PMID 22742582 DOI: 10.1021/Ja305011G  0.395
2012 Kozhukh J, Lippard SJ. Zinc thiolate reactivity toward nitrogen oxides: insights into the interaction of Zn2+ with S-nitrosothiols and implications for nitric oxide synthase. Inorganic Chemistry. 51: 7346-53. PMID 22702952 DOI: 10.1021/Ic3007684  0.328
2012 Wilson JJ, Lippard SJ. In vitro anticancer activity of cis-diammineplatinum(II) complexes with β-diketonate leaving group ligands. Journal of Medicinal Chemistry. 55: 5326-36. PMID 22606945 DOI: 10.1021/Jm3002857  0.372
2012 Graf N, Lippard SJ. Redox activation of metal-based prodrugs as a strategy for drug delivery. Advanced Drug Delivery Reviews. 64: 993-1004. PMID 22289471 DOI: 10.1016/J.Addr.2012.01.007  0.333
2012 Do LH, Xue G, Que L, Lippard SJ. Evaluating the identity and diiron core transformations of a (μ-oxo)diiron(III) complex supported by electron-rich tris(pyridyl-2-methyl)amine ligands. Inorganic Chemistry. 51: 2393-402. PMID 22264120 DOI: 10.1021/Ic202379B  0.654
2012 Do LH, Lippard SJ. ChemInform Abstract: Evolution of Strategies to Prepare Synthetic Mimics of Carboxylate-Bridged Diiron Protein Active Sites Cheminform. 43: no-no. DOI: 10.1002/chin.201206262  0.566
2011 Rosenthal J, Nepomnyashchii AB, Kozhukh J, Bard AJ, Lippard SJ. Synthesis, Photophysics, Electrochemistry and Electrogenerated Chemiluminescence of a Homologous Set of BODIPY-Appended Bipyridine Derivatives. The Journal of Physical Chemistry. C, Nanomaterials and Interfaces. 115: 17993-18001. PMID 23181151 DOI: 10.1021/Jp204487R  0.556
2011 McCormick MS, Lippard SJ. Analysis of substrate access to active sites in bacterial multicomponent monooxygenase hydroxylases: X-ray crystal structure of xenon-pressurized phenol hydroxylase from Pseudomonas sp. OX1. Biochemistry. 50: 11058-69. PMID 22136180 DOI: 10.1021/Bi201248B  0.321
2011 Do LH, Lippard SJ. Evolution of strategies to prepare synthetic mimics of carboxylate-bridged diiron protein active sites. Journal of Inorganic Biochemistry. 105: 1774-85. PMID 22113107 DOI: 10.1016/J.Jinorgbio.2011.08.025  0.646
2011 You Y, Lee S, Kim T, Ohkubo K, Chae WS, Fukuzumi S, Jhon GJ, Nam W, Lippard SJ. Phosphorescent sensor for biological mobile zinc. Journal of the American Chemical Society. 133: 18328-42. PMID 22023085 DOI: 10.1021/Ja207163R  0.531
2011 Do LH, Wang H, Tinberg CE, Dowty E, Yoda Y, Cramer SP, Lippard SJ. Characterization of a synthetic peroxodiiron(III) protein model complex by nuclear resonance vibrational spectroscopy. Chemical Communications (Cambridge, England). 47: 10945-7. PMID 21897991 DOI: 10.1039/C1Cc13836G  0.618
2011 Sartoretto JL, Kalwa H, Pluth MD, Lippard SJ, Michel T. Hydrogen peroxide differentially modulates cardiac myocyte nitric oxide synthesis. Proceedings of the National Academy of Sciences of the United States of America. 108: 15792-7. PMID 21896719 DOI: 10.1073/Pnas.1111331108  0.549
2011 Pluth MD, Chan MR, McQuade LE, Lippard SJ. Seminaphthofluorescein-based fluorescent probes for imaging nitric oxide in live cells. Inorganic Chemistry. 50: 9385-92. PMID 21895023 DOI: 10.1021/Ic200986V  0.566
2011 Li Y, Cao R, Lippard SJ. Design and synthesis of a novel triptycene-based ligand for modeling carboxylate-bridged diiron enzyme active sites. Organic Letters. 13: 5052-5. PMID 21875093 DOI: 10.1021/Ol201882V  0.511
2011 Cao R, McCarthy BD, Lippard SJ. Immobilization, trapping, and anion exchange of perrhenate ion using copper-based tripodal complexes. Inorganic Chemistry. 50: 9499-507. PMID 21870794 DOI: 10.1021/Ic201172R  0.479
2011 You Y, Han Y, Lee YM, Park SY, Nam W, Lippard SJ. Phosphorescent sensor for robust quantification of copper(II) ion. Journal of the American Chemical Society. 133: 11488-91. PMID 21749087 DOI: 10.1021/Ja204997C  0.502
2011 Do LH, Lippard SJ. Toward functional carboxylate-bridged diiron protein mimics: achieving structural stability and conformational flexibility using a macrocylic ligand framework. Journal of the American Chemical Society. 133: 10568-81. PMID 21682286 DOI: 10.1021/Ja2021312  0.683
2011 Pluth MD, Tomat E, Lippard SJ. Biochemistry of mobile zinc and nitric oxide revealed by fluorescent sensors. Annual Review of Biochemistry. 80: 333-55. PMID 21675918 DOI: 10.1146/Annurev-Biochem-061009-091643  0.726
2011 Bochevarov AD, Li J, Song WJ, Friesner RA, Lippard SJ. Insights into the different dioxygen activation pathways of methane and toluene monooxygenase hydroxylases. Journal of the American Chemical Society. 133: 7384-97. PMID 21517016 DOI: 10.1021/Ja110287Y  0.494
2011 Tinberg CE, Lippard SJ. Dioxygen activation in soluble methane monooxygenase. Accounts of Chemical Research. 44: 280-8. PMID 21391602 DOI: 10.1021/Ar1001473  0.318
2011 Wilson JJ, Lippard SJ. Synthesis, characterization, and cytotoxicity of platinum(IV) carbamate complexes. Inorganic Chemistry. 50: 3103-15. PMID 21361279 DOI: 10.1021/Ic2000816  0.331
2011 Buccella D, Horowitz JA, Lippard SJ. Understanding zinc quantification with existing and advanced ditopic fluorescent Zinpyr sensors. Journal of the American Chemical Society. 133: 4101-14. PMID 21351756 DOI: 10.1021/Ja110907M  0.3
2011 Tonzetich ZJ, Héroguel F, Do LH, Lippard SJ. Chemistry of nitrosyliron complexes supported by a β-diketiminate ligand. Inorganic Chemistry. 50: 1570-9. PMID 21244036 DOI: 10.1021/Ic102300D  0.795
2011 Dhar S, Kolishetti N, Lippard SJ, Farokhzad OC. Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 108: 1850-5. PMID 21233423 DOI: 10.1073/Pnas.1011379108  0.592
2010 Bochevarov AD, Friesner RA, Lippard SJ. The prediction of Fe Mössbauer parameters by the density functional theory: a benchmark study. Journal of Chemical Theory and Computation. 6: 3735-3749. PMID 21258606 DOI: 10.1021/Ct100398M  0.493
2010 Todd RC, Lippard SJ. Consequences of cisplatin binding on nucleosome structure and dynamics Chemistry and Biology. 17: 1334-1343. PMID 21168769 DOI: 10.1016/J.Chembiol.2010.10.018  0.307
2010 Tinberg CE, Tonzetich ZJ, Wang H, Do LH, Yoda Y, Cramer SP, Lippard SJ. Characterization of iron dinitrosyl species formed in the reaction of nitric oxide with a biological Rieske center. Journal of the American Chemical Society. 132: 18168-76. PMID 21133361 DOI: 10.1021/Ja106290P  0.791
2010 Cao R, Müller P, Lippard SJ. Tripodal tris-tacn and tris-dpa platforms for assembling phosphate-templated trimetallic centers Journal of the American Chemical Society. 132: 17366-17369. PMID 21090678 DOI: 10.1021/Ja108212V  0.5
2010 Du P, Lippard SJ. A highly selective turn-on colorimetric, red fluorescent sensor for detecting mobile zinc in living cells. Inorganic Chemistry. 49: 10753-5. PMID 21028775 DOI: 10.1021/Ic101569A  0.511
2010 Kolishetti N, Dhar S, Valencia PM, Lin LQ, Karnik R, Lippard SJ, Langer R, Farokhzad OC. Engineering of self-assembled nanoparticle platform for precisely controlled combination drug therapy. Proceedings of the National Academy of Sciences of the United States of America. 107: 17939-44. PMID 20921363 DOI: 10.1073/Pnas.1011368107  0.596
2010 Tomat E, Lippard SJ. Ratiometric and intensity-based zinc sensors built on rhodol and rhodamine platforms. Inorganic Chemistry. 49: 9113-5. PMID 20860360 DOI: 10.1021/Ic101513A  0.643
2010 McQuade LE, Lippard SJ. Cell-trappable quinoline-derivatized fluoresceins for selective and reversible biological Zn(II) detection Inorganic Chemistry. 49: 9535-9545. PMID 20849126 DOI: 10.1021/Ic1012507  0.329
2010 McQuade LE, Pluth MD, Lippard SJ. Mechanism of nitric oxide reactivity and fluorescence enhancement of the NO-specific probe CuFL1. Inorganic Chemistry. 49: 8025-33. PMID 20704359 DOI: 10.1021/Ic101054U  0.604
2010 McQuade LE, Lippard SJ. Fluorescence-based nitric oxide sensing by Cu(II) complexes that can be trapped in living cells Inorganic Chemistry. 49: 7464-7471. PMID 20690755 DOI: 10.1021/Ic100802Q  0.334
2010 Tonzetich ZJ, McQuade LE, Lippard SJ. Detecting and understanding the roles of nitric oxide in biology. Inorganic Chemistry. 49: 6338-48. PMID 20666391 DOI: 10.1021/Ic9022757  0.703
2010 Lee T, Zhang XA, Dhar S, Faas H, Lippard SJ, Jasanoff A. In vivo imaging with a cell-permeable porphyrin-based MRI contrast agent. Chemistry & Biology. 17: 665-73. PMID 20609416 DOI: 10.1016/J.Chembiol.2010.05.009  0.588
2010 Todd RC, Lippard SJ. Structure of duplex DNA containing the cisplatin 1,2-{Pt(NH3)2}2+-d(GpG) cross-link at 1.77Å resolution Journal of Inorganic Biochemistry. 104: 902-908. PMID 20541266 DOI: 10.1016/J.Jinorgbio.2010.04.005  0.338
2010 Friedle S, Reisner E, Lippard SJ. Current challenges of modeling diiron enzyme active sites for dioxygen activation by biomimetic synthetic complexes Chemical Society Reviews. 39: 2768-2779. PMID 20485834 DOI: 10.1039/C003079C  0.589
2010 You Y, Tomat E, Hwang K, Atanasijevic T, Nam W, Jasanoff AP, Lippard SJ. Manganese displacement from Zinpyr-1 allows zinc detection by fluorescence microscopy and magnetic resonance imaging. Chemical Communications (Cambridge, England). 46: 4139-41. PMID 20454746 DOI: 10.1039/C0Cc00179A  0.687
2010 Wang D, Zhu G, Huang X, Lippard SJ. X-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adduct. Proceedings of the National Academy of Sciences of the United States of America. 107: 9584-9. PMID 20448203 DOI: 10.1073/Pnas.1002565107  0.342
2010 Ang WH, Myint M, Lippard SJ. Transcription inhibition by platinum-DNA cross-links in live mammalian cells Journal of the American Chemical Society. 132: 7429-7435. PMID 20443565 DOI: 10.1021/Ja101495V  0.304
2010 Tonzetich ZJ, Wang H, Mitra D, Tinberg CE, Do LH, Jenney FE, Adams MW, Cramer SP, Lippard SJ. Identification of protein-bound dinitrosyl iron complexes by nuclear resonance vibrational spectroscopy. Journal of the American Chemical Society. 132: 6914-6. PMID 20429508 DOI: 10.1021/Ja101002F  0.782
2010 Wilson JJ, Fedoce Lopes J, Lippard SJ. Synthesis, characterization, and photophysical properties of three platinum(II) complexes bearing fluorescent analogues of the Di-2-pyridylmethane ligand. Inorganic Chemistry. 49: 5303-15. PMID 20423108 DOI: 10.1021/Ic100411P  0.4
2010 Pluth MD, McQuade LE, Lippard SJ. Cell-trappable fluorescent probes for nitric oxide visualization in living cells. Organic Letters. 12: 2318-21. PMID 20405852 DOI: 10.1021/Ol1006289  0.545
2010 Rosenthal J, Lippard SJ. Direct detection of nitroxyl in aqueous solution using a tripodal copper(II) BODIPY complex. Journal of the American Chemical Society. 132: 5536-7. PMID 20355724 DOI: 10.1021/Ja909148V  0.58
2010 Tangen E, Conradie J, Franz K, Friedle S, Telser J, Lippard SJ, Ghosh A. Electronic structure of a paramagnetic {MNO}6 complex: MnNO 5,5-tropocoronand Inorganic Chemistry. 49: 2701-2705. PMID 20166686 DOI: 10.1021/Ic901860X  0.667
2010 Tomat E, Lippard SJ. Imaging mobile zinc in biology. Current Opinion in Chemical Biology. 14: 225-30. PMID 20097117 DOI: 10.1016/J.Cbpa.2009.12.010  0.623
2010 Do LH, Hayashi T, Moënne-Loccoz P, Lippard SJ. Carboxylate as the protonation site in (Peroxo)diiron(III) model complexes of soluble methane monooxygenase and related diiron proteins. Journal of the American Chemical Society. 132: 1273-5. PMID 20055391 DOI: 10.1021/Ja909718F  0.665
2010 Dhar S, Daniel WL, Giljohann DA, Mirkin CA, Lippard SJ. Erratum: Polyvalent oligonucleotide gold nanoparticle conjugates as delivery vehicles for platinum(IV) warheads (Journal of the American Chemical Society (2009) 131 (14652-14653)) Journal of the American Chemical Society. 132. DOI: 10.1021/Ja100560G  0.572
2010 Friedle S, Reisner E, Lippard SJ. ChemInform Abstract: Current Challenges of Modeling Diiron Enzyme Active Sites for Dioxygen Activation by Biomimetic Synthetic Complexes Cheminform. 41: no-no. DOI: 10.1002/chin.201044271  0.466
2010 FEIG AL, LIPPARD SJ. ChemInform Abstract: Reactions of Non-Heme Iron(II) Centers with Dioxygen in Biology and Chemistry. Cheminform. 26: no-no. DOI: 10.1002/chin.199505318  0.695
2010 CARNAHAN EM, PROTASIEWICZ JD, LIPPARD SJ. ChemInform Abstract: 15 Years of Reductive Coupling: What Have We Learned? Cheminform. 24: no-no. DOI: 10.1002/chin.199326259  0.619
2010 PROTASIEWICZ JD, LIPPARD SJ. ChemInform Abstract: Vanadium-Promoted Reductive Coupling of CO and Facile Hydrogenation to Form cis-Disiloxyethylenes. Cheminform. 22: no-no. DOI: 10.1002/chin.199145242  0.639
2009 Todd RC, Lippard SJ. Inhibition of transcription by platinum antitumor compounds Metallomics. 1: 280-291. PMID 20046924 DOI: 10.1039/B907567D  0.31
2009 Lovejoy KS, Lippard SJ. Non-traditional platinum compounds for improved accumulation, oral bioavailability, and tumor targeting Dalton Transactions. 10651-10659. PMID 20023892 DOI: 10.1039/B913896J  0.339
2009 Dhar S, Lippard SJ. Mitaplatin, a potent fusion of cisplatin and the orphan drug dichloroacetate Proceedings of the National Academy of Sciences of the United States of America. 106: 22199-22204. PMID 20007777 DOI: 10.1073/Pnas.0912276106  0.618
2009 Tinberg CE, Lippard SJ. Revisiting the mechanism of dioxygen activation in soluble methane monooxygenase from M. capsulatus (Bath): Evidence for a multi-step, proton-dependent reaction pathway Biochemistry. 48: 12145-12158. PMID 19921958 DOI: 10.1021/Bi901672N  0.306
2009 Do LH, Lippard SJ. 2-Phenoxypyridyl dinucleating ligands for assembly of diiron(II) complexes: efficient reactivity with O(2) to form (mu-Oxo)diiron(III) units. Inorganic Chemistry. 48: 10708-19. PMID 19845332 DOI: 10.1021/Ic901711C  0.645
2009 Dhar S, Daniel WL, Giljohann DA, Mirkin CA, Lippard SJ. Polyvalent oligonucleotide gold nanoparticle conjugates as delivery vehicles for platinum(IV) warheads. Journal of the American Chemical Society. 131: 14652-3. PMID 19778015 DOI: 10.1021/Ja9071282  0.616
2009 Friedle S, Kodanko JJ, Morys AJ, Hayashi T, Moënne-Loccoz P, Lippard SJ. Modeling the syn disposition of nitrogen donors in non-heme diiron enzymes. Synthesis, characterization, and hydrogen peroxide reactivity of diiron(III) complexes with the syn N-donor ligand H2BPG2DEV. Journal of the American Chemical Society. 131: 14508-20. PMID 19757795 DOI: 10.1021/Ja906137Y  0.691
2009 Wong BA, Friedle S, Lippard SJ. Subtle modification of 2.2-dipicolylamine lowers the affinity and improves the turn-on of Zn(II)-selective fluorescent sensors Inorganic Chemistry. 48: 7009-7011. PMID 19572729 DOI: 10.1021/Ic900990W  0.303
2009 Tonzetich ZJ, Do LH, Lippard SJ. Dinitrosyl iron complexes relevant to Rieske cluster nitrosylation. Journal of the American Chemical Society. 131: 7964-5. PMID 19459625 DOI: 10.1021/Ja9030159  0.79
2009 Wong BA, Friedle S, Lippard SJ. Solution and fluorescence properties of symmetric dipicolylamine-containing dichlorofluorescein-based Zn sensors Journal of the American Chemical Society. 131: 7142-7152. PMID 19405465 DOI: 10.1021/Ja900980U  0.317
2009 Altmann KH, Buchner J, Kessler H, Diederich F, Kräutler B, Lippard S, Liskamp R, Müller K, Nolan EM, Samori B, Schneider G, Schreiber SL, Schwalbe H, Toniolo C, van Boeckel CA, et al. The state of the art of chemical biology. Chembiochem : a European Journal of Chemical Biology. 10: 16-29. PMID 19115274 DOI: 10.1002/cbic.200800758  0.617
2009 Guggenheim ER, Xu D, Zhang CX, Chang PV, Lippard SJ. Photoaffinity isolation and identification of proteins in cancer cell extracts that bind to platinum-modified DNA. Chembiochem : a European Journal of Chemical Biology. 10: 141-57. PMID 19053130 DOI: 10.1002/Cbic.200800471  0.407
2009 Nolan EM, Lippard SJ. Small-molecule fluorescent sensors for investigating zinc metalloneurochemistry. Accounts of Chemical Research. 42: 193-203. PMID 18989940 DOI: 10.1021/Ar8001409  0.605
2009 Friedle S, Lippard SJ. Synthesis, characterization, and oxygenation studies of carboxlate-bridged diiron(II) complexes with aromatic substrates tethered to pyridine ligands and the formation of a unique trinuclear complex European Journal of Inorganic Chemistry. 5506-5515. DOI: 10.1002/Ejic.200900821  0.417
2008 Friedle S, Kodanko JJ, Fornace KL, Lippard SJ. 9-Triptycenecarboxylate-Bridged Diiron(II) Complexes: Capture of the Paddlewheel Geometric Isomer. Journal of Molecular Structure. 890: 317-327. PMID 19915653 DOI: 10.1016/J.Molstruc.2008.05.030  0.689
2008 Dhar S, Gu FX, Langer R, Farokhza OC, Lippard SJ. Targeted delivery of cisplatin to prostate cancer cells by aptamer functionalized Pt(IV) prodrug-PLGA - PEG nanoparticles Proceedings of the National Academy of Sciences of the United States of America. 105: 17356-17361. PMID 18978032 DOI: 10.1073/Pnas.0809154105  0.593
2008 Guggenheim ER, Ondrus AE, Movassaghi M, Lippard SJ. Poly(ADP-ribose) polymerase-1 activity facilitates the dissociation of nuclear proteins from platinum-modified DNA Bioorganic and Medicinal Chemistry. 16: 10121-10128. PMID 18977144 DOI: 10.1016/J.Bmc.2008.09.074  0.724
2008 Tomat E, Nolan EM, Jaworski J, Lippard SJ. Organelle-specific zinc detection using zinpyr-labeled fusion proteins in live cells. Journal of the American Chemical Society. 130: 15776-7. PMID 18973293 DOI: 10.1021/Ja806634E  0.718
2008 Harrop TC, Tonzetich ZJ, Reisner E, Lippard SJ. Reactions of synthetic [2Fe-2S] and [4Fe-4S] clusters with nitric oxide and nitrosothiols. Journal of the American Chemical Society. 130: 15602-10. PMID 18939795 DOI: 10.1021/Ja8054996  0.8
2008 Tennyson AG, Dhar S, Lippard SJ. Synthesis and characterization of {Ni(NO)}10 and {Co(NO) 2}10 complexes supported by thiolate ligands Journal of the American Chemical Society. 130: 15087-15098. PMID 18928257 DOI: 10.1021/Ja803992Y  0.671
2008 Dhar S, Liu Z, Thomale J, Dai H, Lippard SJ. Targeted single-wall carbon nanotube-mediated Pt(IV) prodrug delivery using folate as a homing device. Journal of the American Chemical Society. 130: 11467-76. PMID 18661990 DOI: 10.1021/Ja803036E  0.636
2008 Nolan EM, Lippard SJ. Tools and tactics for the optical detection of mercuric ion. Chemical Reviews. 108: 3443-80. PMID 18652512 DOI: 10.1021/Cr068000Q  0.528
2008 Lovejoy KS, Todd RC, Zhang S, McCormick MS, D'Aquino JA, Reardon JT, Sancar A, Giacomini KM, Lippard SJ. cis-Diammine(pyridine)chloroplatinum(II), a monofunctional platinum(II) antitumor agent: Uptake, structure, function, and prospects. Proceedings of the National Academy of Sciences of the United States of America. 105: 8902-7. PMID 18579768 DOI: 10.1073/Pnas.0803441105  0.365
2008 Kodanko JJ, Lippard SJ. Synthesis and Characterization of a Ditriflate-Bridged, Diiron(II) Complex with Syn-N-Donor Ligands: [Fe(2)(μ-OTf)(2)(PIC(2)DET)(2)](BARF)(2). Inorganica Chimica Acta. 361: 894-900. PMID 18458751 DOI: 10.1016/J.Ica.2007.02.029  0.697
2008 Zhao M, Helms B, Slonkina E, Friedle S, Lee D, Dubois J, Hedman B, Hodgson KO, Fréchet JM, Lippard SJ. Iron complexes of dendrimer-appended carboxylates for activating dioxygen and oxidizing hydrocarbons. Journal of the American Chemical Society. 130: 4352-63. PMID 18331028 DOI: 10.1021/Ja076817A  0.721
2008 Ober M, Lippard SJ. A 1,2-d(GpG) cisplatin intrastrand cross-link influences the rotational and translational setting of DNA in nucleosomes Journal of the American Chemical Society. 130: 2851-2861. PMID 18269283 DOI: 10.1021/Ja710220X  0.303
2008 Zhang XA, Song D, Lippard SJ. A reversible pH-dependent intramolecular pyridine-aldehyde cyclization. The Journal of Organic Chemistry. 73: 734-7. PMID 18081350 DOI: 10.1021/Jo702394V  0.517
2008 Mukhopadhyay S, Barnés CM, Haskel A, Short SM, Barnes KR, Lippard SJ. Conjugated platinum(IV)-peptide complexes for targeting angiogenic tumor vasculature. Bioconjugate Chemistry. 19: 39-49. PMID 17845003 DOI: 10.1021/Bc070031K  0.543
2008 Reisner E, Lippard SJ. Synthesis of Dicarboxylate “C-Clamp” 1,2-Diethynylarene Compounds as Potential Transition-Metal Ion Hosts European Journal of Organic Chemistry. 2008: 156-163. DOI: 10.1002/Ejoc.200700816  0.582
2008 Stahl SS, Lippard SJ. Dioxygen and alkane activation by iron-containing enzymes Iron Metabolism: Inorganic Biochemistry and Regulatory Mechanisms. 303-321. DOI: 10.1002/9783527613700.ch18  0.489
2008 Tinberg CE, Beauvais LG, Lippard SJ. Hydrocarbon oxidation by the catalytic intermediates in soluble methane monooxygenase from Methylococcus capsulatus (Bath) Acs National Meeting Book of Abstracts.  0.7
2007 Murray LJ, García-Serres R, McCormick MS, Davydov R, Naik SG, Kim SH, Hoffman BM, Huynh BH, Lippard SJ. Dioxygen activation at non-heme diiron centers: oxidation of a proximal residue in the I100W variant of toluene/o-xylene monooxygenase hydroxylase. Biochemistry. 46: 14795-809. PMID 18044971 DOI: 10.1021/Bi7017128  0.745
2007 Reisner E, Telser J, Lippard SJ. A planar carboxylate-rich tetraironII complex and its conversion to linear triironII and paddlewheel diironII complexes. Inorganic Chemistry. 46: 10754-70. PMID 17997551 DOI: 10.1021/Ic701663J  0.596
2007 Reisner E, Abikoff TC, Lippard SJ. Influence of steric hindrance on the core geometry and sulfoxidation chemistry of carboxylate-rich diiron(II) complexes. Inorganic Chemistry. 46: 10229-40. PMID 17973373 DOI: 10.1021/Ic7014176  0.616
2007 Murray LJ, Naik SG, Ortillo DO, García-Serres R, Lee JK, Huynh BH, Lippard SJ. Characterization of the arene-oxidizing intermediate in ToMOH as a diiron(III) species. Journal of the American Chemical Society. 129: 14500-10. PMID 17967027 DOI: 10.1021/Ja076121H  0.69
2007 Conradie J, Quarless DA, Hsu HF, Harrop TC, Lippard SJ, Koch SA, Ghosh A. Electronic structure and FeNO conformation of nonheme iron-thiolate-NO complexes: an experimental and DFT study. Journal of the American Chemical Society. 129: 10446-56. PMID 17685516 DOI: 10.1021/Ja0719982  0.815
2007 Harrop TC, Song D, Lippard SJ. Reactivity pathways for nitric oxide and nitrosonium with iron complexes in biologically relevant sulfur coordination spheres. Journal of Inorganic Biochemistry. 101: 1730-8. PMID 17618690 DOI: 10.1016/J.Jinorgbio.2007.05.006  0.819
2007 Kim Y, Feng X, Lippard SJ. Synthesis, structure, and properties of a mixed-valent triiron complex of tetramethyl reductic acid, an ascorbic acid analogue, and its relationship to a functional non-heme iron oxidation catalyst system. Inorganic Chemistry. 46: 6099-107. PMID 17579400 DOI: 10.1021/Ic700622A  0.398
2007 Zhang XA, Lovejoy KS, Jasanoff A, Lippard SJ. Water-soluble porphyrins as a dual-function molecular imaging platform for MRI and fluorescence zinc sensing. Proceedings of the National Academy of Sciences of the United States of America. 104: 10780-5. PMID 17578918 DOI: 10.1073/Pnas.0702393104  0.313
2007 Feazell RP, Nakayama-Ratchford N, Dai H, Lippard SJ. Soluble single-walled carbon nanotubes as longboat delivery systems for platinum(IV) anticancer drug design. Journal of the American Chemical Society. 129: 8438-9. PMID 17569542 DOI: 10.1021/Ja073231F  0.326
2007 Murray LJ, Lippard SJ. Substrate trafficking and dioxygen activation in bacterial multicomponent monooxygenases. Accounts of Chemical Research. 40: 466-74. PMID 17518435 DOI: 10.1021/Ar600040E  0.687
2007 Todd RC, Lovejoy KS, Lippard SJ. Understanding the effect of carbonate ion on cisplatin binding to DNA Journal of the American Chemical Society. 129: 6370-6371. PMID 17465550 DOI: 10.1021/Ja071143P  0.3
2007 Nolan EM, Lippard SJ. Turn-on and ratiometric mercury sensing in water with a red-emitting probe. Journal of the American Chemical Society. 129: 5910-8. PMID 17429971 DOI: 10.1021/Ja068879R  0.612
2007 Mantri Y, Lippard SJ, Baik MH. Bifunctional binding of cisplatin to DNA: why does cisplatin form 1,2-intrastrand cross-links with ag but not with GA? Journal of the American Chemical Society. 129: 5023-30. PMID 17402732 DOI: 10.1021/Ja067631Z  0.781
2007 Rinaldo D, Philipp DM, Lippard SJ, Friesner RA. Intermediates in dioxygen activation by methane monooxygenase: a QM/MM study. Journal of the American Chemical Society. 129: 3135-47. PMID 17326634 DOI: 10.1021/Ja0654074  0.529
2007 Newcomb M, Lansakara-P DS, Kim HY, Chandrasena RE, Lippard SJ, Beauvais LG, Murray LJ, Izzo V, Hollenberg PF, Coon MJ. Products from enzyme-catalyzed oxidations of norcarenes. The Journal of Organic Chemistry. 72: 1128-33. PMID 17288367 DOI: 10.1021/Jo061865J  0.779
2007 Newcomb M, Chandrasena RE, Lansakara-P DS, Kim HY, Lippard SJ, Beauvais LG, Murray LJ, Izzo V, Hollenberg PF, Coon MJ. Desaturase reactions complicate the use of norcarane as a mechanistic probe. Unraveling the mixture of twenty-plus products formed in enzyme-catalyzed oxidations of norcarane. The Journal of Organic Chemistry. 72: 1121-7. PMID 17288366 DOI: 10.1021/Jo061864R  0.784
2007 Lim MH, Lippard SJ. Metal-based turn-on fluorescent probes for sensing nitric oxide. Accounts of Chemical Research. 40: 41-51. PMID 17226944 DOI: 10.1021/Ar950149T  0.643
2007 Sazinsky MH, Lippard SJ. Correlating structure with function in bacterial multicomponent monooxygenases and related diiron proteins. Accounts of Chemical Research. 39: 558-66. PMID 16906752 DOI: 10.1021/Ar030204V  0.332
2007 Tennyson AG, Do L, Smith RC, Lippard SJ. Selective fluorescence detection of nitroxyl over nitric oxide in buffered aqueous solution using a conjugated metallopolymer Polyhedron. 26: 4625-4630. DOI: 10.1016/J.Poly.2007.04.003  0.753
2007 Kukushikin VY, Oskarsson Å, Elding LI, Farrell N, Dunham S, Lippard SJ. Facile Synthesis of Isomerically Pure cis‐Dichlorodiammineplatinum(II), Cisplatin Inorganic Syntheses. 32: 141-144. DOI: 10.1002/9780470132630.Ch23  0.314
2006 Sazinsky MH, Dunten PW, McCormick MS, DiDonato A, Lippard SJ. X-ray structure of a hydroxylase-regulatory protein complex from a hydrocarbon-oxidizing multicomponent monooxygenase, Pseudomonas sp. OX1 phenol hydroxylase. Biochemistry. 45: 15392-404. PMID 17176061 DOI: 10.1021/Bi0618969  0.383
2006 Nolan EM, Ryu JW, Jaworski J, Feazell RP, Sheng M, Lippard SJ. Zinspy sensors with enhanced dynamic range for imaging neuronal cell zinc uptake and mobilization. Journal of the American Chemical Society. 128: 15517-28. PMID 17132019 DOI: 10.1021/Ja065759A  0.611
2006 McCormick MS, Sazinsky MH, Condon KL, Lippard SJ. X-ray crystal structures of manganese(II)-reconstituted and native toluene/o-xylene monooxygenase hydroxylase reveal rotamer shifts in conserved residues and an enhanced view of the protein interior. Journal of the American Chemical Society. 128: 15108-10. PMID 17117860 DOI: 10.1021/Ja064837R  0.342
2006 Nolan EM, Jaworski J, Racine ME, Sheng M, Lippard SJ. Midrange affinity fluorescent Zn(II) sensors of the Zinpyr family: syntheses, characterization, and biological imaging applications. Inorganic Chemistry. 45: 9748-57. PMID 17112271 DOI: 10.1021/Ic061137E  0.611
2006 Smith RC, Tennyson AG, Won AC, Lippard SJ. Conjugated metallopolymers for fluorescent turn-on detection of nitric oxide. Inorganic Chemistry. 45: 9367-73. PMID 17083235 DOI: 10.1021/Ic061099Z  0.665
2006 Lim MH, Wong BA, Pitcock WH, Mokshagundam D, Baik MH, Lippard SJ. Direct nitric oxide detection in aqueous solution by copper(II) fluorescein complexes. Journal of the American Chemical Society. 128: 14364-73. PMID 17076510 DOI: 10.1021/Ja064955E  0.718
2006 Do L, Smith RC, Tennyson AG, Lippard SJ. Luminescent properties of water-soluble conjugated metallopolymers and their application to fluorescent nitric oxide detection. Inorganic Chemistry. 45: 8998-9005. PMID 17054360 DOI: 10.1021/Ic060998K  0.74
2006 Lim MH, Lippard SJ. Fluorescent nitric oxide detection by copper complexes bearing anthracenyl and dansyl fluorophore ligands. Inorganic Chemistry. 45: 8980-9. PMID 17054358 DOI: 10.1021/Ic0609913  0.623
2006 Lieberman RL, Kondapalli KC, Shrestha DB, Hakemian AS, Smith SM, Telser J, Kuzelka J, Gupta R, Borovik AS, Lippard SJ, Hoffman BM, Rosenzweig AC, Stemmler TL. Characterization of the particulate methane monooxygenase metal centers in multiple redox states by X-ray absorption spectroscopy. Inorganic Chemistry. 45: 8372-81. PMID 16999437 DOI: 10.1021/Ic060739V  0.792
2006 Goldsmith CR, Lippard SJ. Analogues of Zinpyr-1 provide insight into the mechanism of zinc sensing. Inorganic Chemistry. 45: 6474-8. PMID 16878961 DOI: 10.1021/Ic060378J  0.678
2006 Zhao M, Song D, Lippard SJ. Water induces a structural conversion and accelerates the oxygenation of carboxylate-bridged non-heme diiron enzyme synthetic analogues. Inorganic Chemistry. 45: 6323-30. PMID 16878942 DOI: 10.1021/Ic0602906  0.591
2006 Smith RC, Tennyson AG, Lippard SJ. Polymer-bound dirhodium tetracarboxylate films for fluorescent detection of nitric oxide. Inorganic Chemistry. 45: 6222-6. PMID 16878931 DOI: 10.1021/Ic060070S  0.644
2006 Yoon S, Lippard SJ. Mechanistic studies of the oxidative N-dealkylation of a substrate tethered to carboxylate-bridged diiron(II) complexes, [Fe2(mu-O2CAr(Tol))2(O2CAr(Tol))2(N,N-Bn2en)2]. Inorganic Chemistry. 45: 5438-46. PMID 16813407 DOI: 10.1021/Ic060307K  0.359
2006 Lim MH, Kuang C, Lippard SJ. Nitric oxide-induced fluorescence enhancement by displacement of dansylated ligands from cobalt. Chembiochem : a European Journal of Chemical Biology. 7: 1571-6. PMID 16789059 DOI: 10.1002/Cbic.200600042  0.635
2006 Murray LJ, García-Serres R, Naik S, Huynh BH, Lippard SJ. Dioxygen activation at non-heme diiron centers: characterization of intermediates in a mutant form of toluene/o-xylene monooxygenase hydroxylase. Journal of the American Chemical Society. 128: 7458-9. PMID 16756297 DOI: 10.1021/Ja062762L  0.693
2006 Lim MH, Xu D, Lippard SJ. Visualization of nitric oxide in living cells by a copper-based fluorescent probe. Nature Chemical Biology. 2: 375-80. PMID 16732295 DOI: 10.1038/Nchembio794  0.674
2006 Harrop TC, Song D, Lippard SJ. Interaction of nitric oxide with tetrathiolato iron(II) complexes: relevance to the reaction pathways of iron nitrosyls in sulfur-rich biological coordination environments. Journal of the American Chemical Society. 128: 3528-9. PMID 16536520 DOI: 10.1021/Ja060186N  0.814
2006 Nolan EM, Racine ME, Lippard SJ. Selective Hg(II) detection in aqueous solution with thiol derivatized fluoresceins. Inorganic Chemistry. 45: 2742-9. PMID 16529499 DOI: 10.1021/Ic052083W  0.608
2006 Carson EC, Lippard SJ. Synthesis and oxidation of carboxylate-bridged diiron(II) complexes with substrates tethered to primary alkyl amine ligands. Journal of Inorganic Biochemistry. 100: 1109-17. PMID 16439023 DOI: 10.1016/J.Jinorgbio.2005.11.019  0.394
2006 Carson EC, Lippard SJ. Dioxygen-initiated oxidation of heteroatomic substrates incorporated into ancillary pyridine ligands of carboxylate-rich diiron(II) complexes. Inorganic Chemistry. 45: 837-48. PMID 16411722 DOI: 10.1021/Ic051476S  0.345
2006 Carson EC, Lippard SJ. Synthesis, characterization, and preliminary oxygenation studies of benzyl- and ethyl-substituted pyridine ligands of carboxylate-rich diiron(II) complexes. Inorganic Chemistry. 45: 828-36. PMID 16411721 DOI: 10.1021/Ic051471V  0.338
2006 Goldsmith CR, Lippard SJ. 6-methylpyridyl for pyridyl substitution tunes the properties of fluorescent zinc sensors of the Zinpyr family. Inorganic Chemistry. 45: 555-61. PMID 16411690 DOI: 10.1021/Ic051113S  0.682
2006 Goldsmith CR, Jaworski J, Sheng M, Lippard SJ. Selective labeling of extracellular proteins containing polyhistidine sequences by a fluorescein-nitrilotriacetic acid conjugate. Journal of the American Chemical Society. 128: 418-9. PMID 16402822 DOI: 10.1021/Ja0559754  0.676
2006 Giblin LJ, Chang CJ, Bentley AF, Frederickson C, Lippard SJ, Frederickson CJ. Zinc-secreting Paneth cells studied by ZP fluorescence. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 54: 311-6. PMID 16260591 DOI: 10.1369/Jhc.5A6724.2005  0.421
2005 Nolan EM, Jaworski J, Okamoto K, Hayashi Y, Sheng M, Lippard SJ. QZ1 and QZ2: rapid, reversible quinoline-derivatized fluoresceins for sensing biological Zn(II). Journal of the American Chemical Society. 127: 16812-23. PMID 16316228 DOI: 10.1021/Ja052184T  0.623
2005 Kodanko JJ, Xu D, Song D, Lippard SJ. Iron substitution for sodium in a carboxylate-bridged, heterodinuclear sodium-iron complex. Journal of the American Chemical Society. 127: 16004-5. PMID 16287269 DOI: 10.1021/Ja054943D  0.791
2005 Jung Y, Lippard SJ. RNA polymerase II blockage by cisplatin-damaged DNA. Stability and polyubiquitylation of stalled polymerase. The Journal of Biological Chemistry. 281: 1361-70. PMID 16275646 DOI: 10.1074/Jbc.M509688200  0.308
2005 Kodanko JJ, Morys AJ, Lippard SJ. Synthesis of diethynyltriptycene-linked dipyridyl ligands. Organic Letters. 7: 4585-8. PMID 16209485 DOI: 10.1021/Ol051700H  0.657
2005 Beauvais LG, Lippard SJ. Reactions of the diiron(IV) intermediate Q in soluble methane monooxygenase with fluoromethanes. Biochemical and Biophysical Research Communications. 338: 262-6. PMID 16176805 DOI: 10.1016/J.Bbrc.2005.08.220  0.724
2005 Lim MH, Lippard SJ. Copper complexes for fluorescence-based NO detection in aqueous solution. Journal of the American Chemical Society. 127: 12170-1. PMID 16131164 DOI: 10.1021/Ja053150O  0.643
2005 Danford AJ, Wang D, Wang Q, Tullius TD, Lippard SJ. Platinum anticancer drug damage enforces a particular rotational setting of DNA in nucleosomes. Proceedings of the National Academy of Sciences of the United States of America. 102: 12311-6. PMID 16116097 DOI: 10.1073/Pnas.0506025102  0.607
2005 Smith RC, Tennyson AG, Lim MH, Lippard SJ. Conjugated polymer-based fluorescence turn-on sensor for nitric oxide. Organic Letters. 7: 3573-5. PMID 16048345 DOI: 10.1021/Ol0513903  0.756
2005 Rudd DJ, Sazinsky MH, Lippard SJ, Hedman B, Hodgson KO. X-ray absorption spectroscopic study of the reduced hydroxylases of methane monooxygenase and toluene/o-xylene monooxygenase: Differences in active site structure and effects of the coupling proteins MMOB and ToMOD Inorganic Chemistry. 44: 4546-4554. PMID 15962961 DOI: 10.1021/Ic048794W  0.493
2005 Yoon S, Lippard SJ. Water affects the stereochemistry and dioxygen reactivity of carboxylate-rich diiron(II) models for the diiron centers in dioxygen-dependent non-heme enzymes. Journal of the American Chemical Society. 127: 8386-97. PMID 15941272 DOI: 10.1021/Ja0512531  0.371
2005 Lippard SJ. Hydroxylation of C-H bonds at carboxylate-bridged diiron centres. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 363: 861-77; discussion 1. PMID 15901540 DOI: 10.1098/Rsta.2004.1532  0.349
2005 Beauvais LG, Lippard SJ. Reactions of the peroxo intermediate of soluble methane monooxygenase hydroxylase with ethers. Journal of the American Chemical Society. 127: 7370-8. PMID 15898785 DOI: 10.1021/Ja050865I  0.733
2005 Lu S, Sazinsky MH, Whittaker JW, Lippard SJ, Moënne-Loccoz P. Fourier transform infrared characterization of the azido complex of methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath). Journal of the American Chemical Society. 127: 4148-9. PMID 15783178 DOI: 10.1021/Ja044414U  0.352
2005 Gherman BF, Lippard SJ, Friesner RA. Substrate hydroxylation in methane monooxygenase: quantitative modeling via mixed quantum mechanics/molecular mechanics techniques. Journal of the American Chemical Society. 127: 1025-37. PMID 15656641 DOI: 10.1021/Ja049847B  0.492
2005 Nolan EM, Lippard SJ. MS4, a seminaphthofluorescein-based chemosensor for the ratiometric detection of Hg(II) Journal of Materials Chemistry. 15: 2778-2783. DOI: 10.1039/B501615K  0.593
2005 Woodroofe CC, Lim MH, Bu W, Lippard SJ. Synthesis of Isomerically Pure Carboxylate- and Sulfonate-Substituted Xanthene Fluorophores. Cheminform. 36. DOI: 10.1016/J.Tet.2005.01.024  0.61
2005 Woodroofe CC, Lim MH, Bu W, Lippard SJ. Synthesis of isomerically pure carboxylate- and sulfonate-substituted xanthene fluorophores Tetrahedron. 61: 3097-3105. DOI: 10.1016/j.tet.2005.01.024  0.552
2005 Burdinski D, Cheng K, Lippard SJ. Synthesis of a constrained ligand comprising carboxylate and amine donor groups via direct 1,8-functionalization of positionally protected fluorene Tetrahedron. 61: 1587-1594. DOI: 10.1016/J.Tet.2004.10.111  0.324
2004 Yoon S, Lippard SJ. Water-dependent reactions of diiron(II) carboxylate complexes. Journal of the American Chemical Society. 126: 16692-3. PMID 15612685 DOI: 10.1021/Ja044489Y  0.381
2004 Sazinsky MH, Merkx M, Cadieux E, Tang S, Lippard SJ. Preparation and X-ray structures of metal-free, dicobalt and dimanganese forms of soluble methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath). Biochemistry. 43: 16263-76. PMID 15610020 DOI: 10.1021/Bi048140Z  0.371
2004 Nolan EM, Lippard SJ. The zinspy family of fluorescent zinc sensors: syntheses and spectroscopic investigations. Inorganic Chemistry. 43: 8310-7. PMID 15606177 DOI: 10.1021/Ic048778Z  0.594
2004 Chang CJ, Nolan EM, Jaworski J, Okamoto K, Hayashi Y, Sheng M, Lippard SJ. ZP8, a neuronal zinc sensor with improved dynamic range; imaging zinc in hippocampal slices with two-photon microscopy. Inorganic Chemistry. 43: 6774-9. PMID 15476377 DOI: 10.1021/Ic049293D  0.635
2004 Lim MH, Lippard SJ. Fluorescence-based nitric oxide detection by ruthenium porphyrin fluorophore complexes. Inorganic Chemistry. 43: 6366-70. PMID 15446885 DOI: 10.1021/Ic035418N  0.641
2004 Chatwood LL, Müller J, Gross JD, Wagner G, Lippard SJ. NMR structure of the flavin domain from soluble methane monooxygenase reductase from Methylococcus capsulatus (Bath). Biochemistry. 43: 11983-91. PMID 15379538 DOI: 10.1021/Bi049066N  0.595
2004 Hilderbrand SA, Lippard SJ. Nitric oxide reactivity of fluorophore coordinated carboxylate-bridged diiron(II) and dicobalt(II) complexes. Inorganic Chemistry. 43: 5294-301. PMID 15310207 DOI: 10.1021/Ic049649L  0.405
2004 Hilderbrand SA, Lippard SJ. Cobalt chemistry with mixed aminotroponiminate salicylaldiminate ligands: synthesis, characterization, and nitric oxide reactivity. Inorganic Chemistry. 43: 4674-82. PMID 15257596 DOI: 10.1021/Ic049776H  0.414
2004 Rudd DJ, Sazinsky MH, Merkx M, Lippard SJ, Hedman B, Hodgson KO. Determination by X-ray absorption spectroscopy of the Fe-Fe separation in the oxidized form of the hydroxylase of methane monooxygenase alone and in the presence of MMOD Inorganic Chemistry. 43: 4579-4589. PMID 15257585 DOI: 10.1021/Ic049716B  0.498
2004 Moreira RF, Tshuva EY, Lippard SJ. Catalytic oxidative ring opening of THF promoted by a carboxylate-bridged diiron complex, triarylphosphines, and dioxygen. Inorganic Chemistry. 43: 4427-34. PMID 15236556 DOI: 10.1021/Ic049460+  0.366
2004 Chang CJ, Nolan EM, Jaworski J, Burdette SC, Sheng M, Lippard SJ. Bright fluorescent chemosensor platforms for imaging endogenous pools of neuronal zinc. Chemistry & Biology. 11: 203-10. PMID 15123282 DOI: 10.1016/J.Chembiol.2004.01.017  0.631
2004 Sazinsky MH, Bard J, Di Donato A, Lippard SJ. Crystal structure of the toluene/o-xylene monooxygenase hydroxylase from Pseudomonas stutzeri OX1. Insight into the substrate specificity, substrate channeling, and active site tuning of multicomponent monooxygenases. The Journal of Biological Chemistry. 279: 30600-10. PMID 15096510 DOI: 10.1074/Jbc.M400710200  0.305
2004 Hilderbrand SA, Lim MH, Lippard SJ. Dirhodium tetracarboxylate scaffolds as reversible fluorescence-based nitric oxide sensors. Journal of the American Chemical Society. 126: 4972-8. PMID 15080703 DOI: 10.1021/Ja038471J  0.64
2004 Nolan EM, Burdette SC, Harvey JH, Hilderbrand SA, Lippard SJ. Synthesis and characterization of zinc sensors based on a monosubstituted fluorescein platform. Inorganic Chemistry. 43: 2624-35. PMID 15074981 DOI: 10.1021/Ic035158+  0.597
2004 Carson EC, Lippard SJ. Oxidation of sulfide, phosphine, and benzyl substrates tethered to N-donor pyridine ligands in carboxylate-bridged diiron(II) complexes. Journal of the American Chemical Society. 126: 3412-3. PMID 15025454 DOI: 10.1021/Ja031806C  0.407
2004 Gherman BF, Baik MH, Lippard SJ, Friesner RA. Dioxygen activation in methane monooxygenase: a theoretical study. Journal of the American Chemical Society. 126: 2978-90. PMID 14995216 DOI: 10.1021/Ja036506+  0.639
2004 Yoon S, Lippard SJ. Synthesis and characterization of carboxylate-rich complexes having the [Fe2(mu-OH)2(mu-O2CR)]3+ and [Fe2(mu-O)(mu-O2CR)]3+ cores of O2-dependent diiron enzymes. Journal of the American Chemical Society. 126: 2666-7. PMID 14995160 DOI: 10.1021/Ja031603O  0.35
2004 Kuzelka J, Mukhopadhyay S, Spingler B, Lippard SJ. Synthesis and characterization of Cu(2)(I,I), Cu(2)(I,II), and Cu(2)(II,II) compounds supported by two phthalazine-based ligands: influence of a hydrophobic pocket. Inorganic Chemistry. 43: 1751-61. PMID 14989668 DOI: 10.1021/Ic035009R  0.695
2004 Chang CJ, Jaworski J, Nolan EM, Sheng M, Lippard SJ. A tautomeric zinc sensor for ratiometric fluorescence imaging: application to nitric oxide-induced release of intracellular zinc. Proceedings of the National Academy of Sciences of the United States of America. 101: 1129-34. PMID 14734801 DOI: 10.1073/Pnas.0308079100  0.645
2004 Kuzelka J, Farrell JR, Lippard SJ. Modeling the syn disposition of nitrogen donors at the active sites of carboxylate-bridged diiron enzymes. Enforcing dinuclearity and kinetic stability with a 1,2-diethynylbenzene-based ligand. Inorganic Chemistry. 42: 8652-62. PMID 14686842 DOI: 10.1021/Ic034928E  0.374
2004 Clark MA, Hilderbrand SA, Lippard SJ. Synthesis of fluorescein derivatives containing metal-coordinating heterocycles Tetrahedron Letters. 45: 7129-7131. DOI: 10.1016/J.Tetlet.2004.07.131  0.458
2004 Yoon S, Kelly AE, Lippard SJ. Di- and tetra-bridged diiron(II) complexes with four terphenyl-derived carboxylates and two water molecules Polyhedron. 23: 2805-2812. DOI: 10.1016/J.Poly.2004.06.019  0.385
2003 Baik MH, Friesner RA, Lippard SJ. cis-[Pt(NH3)2(L)]2+/+ (L = Cl, H2O, NH3) binding to purines and CO: does pi-back-donation play a role? Inorganic Chemistry. 42: 8615-7. PMID 14686835 DOI: 10.1021/Ic035022B  0.625
2003 Yoon S, Lippard SJ. Synthesis, characterization, and dioxygen reactivity of tetracarboxylate-bridged Diiron(II) complexes with coordinated substrates. Inorganic Chemistry. 42: 8606-8. PMID 14686832 DOI: 10.1021/Ic0350133  0.385
2003 Nolan EM, Lippard SJ. A "turn-on" fluorescent sensor for the selective detection of mercuric ion in aqueous media. Journal of the American Chemical Society. 125: 14270-1. PMID 14624563 DOI: 10.1021/Ja037995G  0.594
2003 Baik MH, Friesner RA, Lippard SJ. Theoretical study of cisplatin binding to purine bases: why does cisplatin prefer guanine over adenine? Journal of the American Chemical Society. 125: 14082-92. PMID 14611245 DOI: 10.1021/Ja036960D  0.64
2003 Kuzelka J, Mukhopadhyay S, Spingler B, Lippard SJ. Modeling features of the non-heme diiron cores in O2-activating enzymes through the synthesis, characterization, and oxidation of 1,8-naphthyridine-based complexes. Inorganic Chemistry. 42: 6447-57. PMID 14514321 DOI: 10.1021/Ic0345976  0.713
2003 Baik MH, Newcomb M, Friesner RA, Lippard SJ. Mechanistic studies on the hydroxylation of methane by methane monooxygenase. Chemical Reviews. 103: 2385-419. PMID 12797835 DOI: 10.1021/Cr950244F  0.594
2003 Clark MA, Duffy K, Tibrewala J, Lippard SJ. Synthesis and metal-binding properties of chelating fluorescein derivatives. Organic Letters. 5: 2051-4. PMID 12790526 DOI: 10.1021/Ol0344570  0.443
2003 Guallar V, Baik MH, Lippard SJ, Friesner RA. Peripheral heme substituents control the hydrogen-atom abstraction chemistry in cytochromes P450. Proceedings of the National Academy of Sciences of the United States of America. 100: 6998-7002. PMID 12771375 DOI: 10.1073/Pnas.0732000100  0.626
2003 Kopp DA, Berg EA, Costello CE, Lippard SJ. Structural features of covalently cross-linked hydroxylase and reductase proteins of soluble methane monooxygenase as revealed by mass spectrometric analysis Journal of Biological Chemistry. 278: 20939-20945. PMID 12660237 DOI: 10.1074/Jbc.M301581200  0.321
2003 Wirstam M, Lippard SJ, Friesner RA. Reversible dioxygen binding to hemerythrin. Journal of the American Chemical Society. 125: 3980-7. PMID 12656634 DOI: 10.1021/Ja017692R  0.493
2003 Boerzel H, Koeckert M, Bu W, Spingler B, Lippard SJ. Zinc-bound thiolate-disulfide exchange: a strategy for inhibiting metallo-beta-lactamases. Inorganic Chemistry. 42: 1604-15. PMID 12611529 DOI: 10.1021/Ic025624F  0.582
2003 Burdette SC, Frederickson CJ, Bu W, Lippard SJ. ZP4, an improved neuronal Zn2+ sensor of the Zinpyr family. Journal of the American Chemical Society. 125: 1778-87. PMID 12580603 DOI: 10.1021/Ja0287377  0.327
2003 Blazyk JL, Lippard SJ. Expression and characterization of ferredoxin and flavin adenine dinucleotide binding domains of the reductase component of soluble methane monooxygenase from Methylococcus capsulatus (Bath). Biochemistry. 41: 15780-94. PMID 12501207 DOI: 10.1021/Bi026757F  0.326
2003 Farrell JR, Stiles D, Bu W, Lippard SJ. Preparation of macrocyclic and 'C-clamp' dicarboxylate compounds Tetrahedron. 59: 2463-2469. DOI: 10.1016/S0040-4020(03)00256-4  0.3
2003 Friesner RA, Baik MH, Gherman BF, Guallar V, Wirstam M, Murphy RB, Lippard SJ. How iron-containing proteins control dioxygen chemistry: A detailed atomic level description via accurate quantum chemical and mixed quantum mechanics/molecular mechanics calculations Coordination Chemistry Reviews. 238: 267-290. DOI: 10.1016/S0010-8545(02)00284-9  0.635
2002 Baik MH, Gherman BF, Friesner RA, Lippard SJ. Hydroxylation of methane by non-heme diiron enzymes: molecular orbital analysis of C-H bond activation by reactive intermediate Q. Journal of the American Chemical Society. 124: 14608-15. PMID 12465971 DOI: 10.1021/Ja026794U  0.623
2002 Silverman AP, Bu W, Cohen SM, Lippard SJ. 2.4-A crystal structure of the asymmetric platinum complex [Pt(ammine)(cyclohexylamine)]2+ bound to a dodecamer DNA duplex. The Journal of Biological Chemistry. 277: 49743-9. PMID 12377787 DOI: 10.1074/Jbc.M206979200  0.506
2002 Zamble DB, Mikata Y, Eng CH, Sandman KE, Lippard SJ. Testis-specific HMG-domain protein alters the responses of cells to cisplatin. Journal of Inorganic Biochemistry. 91: 451-62. PMID 12175937 DOI: 10.1016/S0162-0134(02)00472-5  0.614
2002 Ambundo EA, Friesner RA, Lippard SJ. Reactions of methane monooxygenase intermediate Q with derivatized methanes. Journal of the American Chemical Society. 124: 8770-1. PMID 12137510 DOI: 10.1021/Ja0265759  0.488
2002 Lee D, DuBois JL, Pierce B, Hedman B, Hodgson KO, Hendrich MP, Lippard SJ. Structural and spectroscopic studies of valence-delocalized diiron(II,III) complexes dupported by carboxylate-only bridging ligands. Inorganic Chemistry. 41: 3172-82. PMID 12054996 DOI: 10.1021/Ic011050N  0.713
2002 Guallar V, Gherman BF, Lippard SJ, Friesner RA. Quantum chemical studies of methane monooxygenase: comparision with P450. Current Opinion in Chemical Biology. 6: 236-42. PMID 12039010 DOI: 10.1016/S1367-5931(02)00310-1  0.498
2002 Lee D, Lippard SJ. Modeling dioxygen-activating centers in non-heme diiron enzymes: carboxylate shifts in diiron(II) complexes supported by sterically hindered carboxylate ligands. Inorganic Chemistry. 41: 2704-19. PMID 12005495 DOI: 10.1021/Ic020186Y  0.673
2002 Bino A, Ardon M, Lee D, Spingler B, Lippard SJ. Synthesis and structure of [Fe(13)O(4)F(24)(OMe)(12)](5-): the first open-shell Keggin ion. Journal of the American Chemical Society. 124: 4578-9. PMID 11971702 DOI: 10.1021/Ja025590A  0.74
2002 Baik MH, Friesner RA, Lippard SJ. Theoretical study on the stability of N-glycosyl bonds: why does N7-platination not promote depurination? Journal of the American Chemical Society. 124: 4495-503. PMID 11960480 DOI: 10.1021/Ja017588+  0.617
2002 Lee D, Pierce B, Krebs C, Hendrich MP, Huynh BH, Lippard SJ. Functional mimic of dioxygen-activating centers in non-heme diiron enzymes: mechanistic implications of paramagnetic intermediates in the reactions between diiron(II) complexes and dioxygen. Journal of the American Chemical Society. 124: 3993-4007. PMID 11942838 DOI: 10.1021/Ja012251T  0.661
2002 Guallar V, Gherman BF, Miller WH, Lippard SJ, Friesner RA. Dynamics of alkane hydroxylation at the non-heme diiron center in methane monooxygenase. Journal of the American Chemical Society. 124: 3377-84. PMID 11916423 DOI: 10.1021/Ja0167248  0.489
2002 Lee KB, Wang D, Lippard SJ, Sharp PA. Transcription-coupled and DNA damage-dependent ubiquitination of RNA polymerase II in vitro. Proceedings of the National Academy of Sciences of the United States of America. 99: 4239-44. PMID 11904382 DOI: 10.1073/Pnas.072068399  0.307
2002 Smoukov SK, Kopp DA, Valentine AM, Davydov R, Lippard SJ, Hoffman BM. Product binding to the diiron(III) and mixed-valence diiron centers of methane monooxygenase hydroxylase studied by (1,2)H and (19)F ENDOR spectroscopy. Journal of the American Chemical Society. 124: 2657-63. PMID 11890816 DOI: 10.1021/Ja010123Z  0.692
2002 Tshuva EY, Lee D, Bu W, Lippard SJ. Catalytic oxidation by a carboxylate-bridged non-heme diiron complex. Journal of the American Chemical Society. 124: 2416-7. PMID 11890772 DOI: 10.1021/Ja017890I  0.657
2002 Lee D, Lippard SJ. Synthetic analogue of the [Fe(2)(mu-OH)(2)(mu-O(2)CR)](3+) core of soluble methane monooxygenase hydroxylase via synthesis and dioxygen reactivity of carboxylate-bridged diiron(II) complexes. Inorganic Chemistry. 41: 827-37. PMID 11849083 DOI: 10.1021/Ic011008S  0.659
2002 Lee D, Hung PL, Spingler B, Lippard SJ. Sterically hindered carboxylate ligands support water-bridged dimetallic centers that model features of metallohydrolase active sites. Inorganic Chemistry. 41: 521-31. PMID 11825079 DOI: 10.1021/Ic0107431  0.717
2002 Müller J, Lugovskoy AA, Wagner G, Lippard SJ. NMR structure of the [2Fe-2S] ferredoxin domain from soluble methane monooxygenase reductase and interaction with its hydroxylase. Biochemistry. 41: 42-51. PMID 11772001 DOI: 10.1021/Bi015668K  0.618
2002 Lee D, Lippard SJ. Structural flexibility within a sterically hindered ligand platform: Mononuclear iron(II) carboxylate complexes as subsite models for diiron(II) centers Inorganica Chimica Acta. 341: 1-11. DOI: 10.1016/S0020-1693(02)01200-8  0.682
2002 Kuzelka J, Spingler B, Lippard SJ. Carboxylate-bridged diiron(II) complexes with a sterically hindered phthalazine ligand Inorganica Chimica Acta. 337: 212-222. DOI: 10.1016/S0020-1693(02)00990-8  0.619
2001 He C, DuBois JL, Hedman B, Hodgson KO, Lippard SJ. A Short Copper-Copper Distance in a (μ-1,2-Peroxo)dicopper(II) Complex Having a 1,8-Naphthyridine Unit as an Additional Bridge. Angewandte Chemie (International Ed. in English). 40: 1484-1487. PMID 29712360 DOI: 10.1002/1521-3773(20010417)40:8<1484::Aid-Anie1484>3.0.Co;2-Z  0.606
2001 Merkx M, Kopp DA, Sazinsky MH, Blazyk JL, Müller J, Lippard SJ. Dioxygen Activation and Methane Hydroxylation by Soluble Methane Monooxygenase: A Tale of Two Irons and Three Proteins. Angewandte Chemie (International Ed. in English). 40: 2782-2807. PMID 29711993 DOI: 10.1002/1521-3773(20010803)40:15<2782::Aid-Anie2782>3.0.Co;2-P  0.56
2001 Lee D, Sorace L, Caneschi A, Lippard SJ. Hydroxo-bridged Cubane-type tetrairon(II) clusters supported by sterically-hindered carboxylate ligands. Inorganic Chemistry. 40: 6774-81. PMID 11735490 DOI: 10.1021/Ic010726B  0.669
2001 Kopp DA, Gassner GT, Blazyk JL, Lippard SJ. Electron-transfer reactions of the reductase component of soluble methane monooxygenase from Methylococcus capsulatus (Bath) Biochemistry. 40: 14932-14941. PMID 11732913 DOI: 10.1021/Bi015556T  0.312
2001 Spingler B, Whittington DA, Lippard SJ. 2.4 A crystal structure of an oxaliplatin 1,2-d(GpG) intrastrand cross-link in a DNA dodecamer duplex. Inorganic Chemistry. 40: 5596-602. PMID 11599959 DOI: 10.1021/Ic010790T  0.575
2001 Jung Y, Mikata Y, Lippard SJ. Kinetic studies of the TATA-binding protein interaction with cisplatin-modified DNA. The Journal of Biological Chemistry. 276: 43589-96. PMID 11568187 DOI: 10.1074/Jbc.M108299200  0.304
2001 Cohen SM, Lippard SJ. Cisplatin: from DNA damage to cancer chemotherapy. Progress in Nucleic Acid Research and Molecular Biology. 67: 93-130. PMID 11525387 DOI: 10.1016/S0079-6603(01)67026-0  0.453
2001 Wei M, Cohen SM, Silverman AP, Lippard SJ. Effects of spectator ligands on the specific recognition of intrastrand platinum-DNA cross-links by high mobility group box and TATA-binding proteins. The Journal of Biological Chemistry. 276: 38774-80. PMID 11514569 DOI: 10.1074/Jbc.M106374200  0.483
2001 Mizoguchi TJ, Kuzelka J, Spingler B, DuBois JL, Davydov RM, Hedman B, Hodgson KO, Lippard SJ. Synthesis and spectroscopic studies of non-heme diiron(III) species with a terminal hydroperoxide ligand: models for hemerythrin. Inorganic Chemistry. 40: 4662-73. PMID 11511213 DOI: 10.1021/Ic010076B  0.675
2001 Merkx M, Kopp DA, Sazinsky MH, Blazyk JL, Müller J, Lippard SJ. Dioxygen Activation and Methane Hydroxylation by Soluble Methane Monooxygenase: A Tale of Two Irons and Three Proteins A list of abbreviations can be found in Section 7. Angewandte Chemie (International Ed. in English). 40: 2782-2807. PMID 11500872 DOI: 10.1002/1521-3773(20010803)40:15<2782::AID-ANIE2782>3.0.CO;2-P  0.508
2001 Burdette SC, Walkup GK, Spingler B, Tsien RY, Lippard SJ. Fluorescent sensors for Zn(2+) based on a fluorescein platform: synthesis, properties and intracellular distribution. Journal of the American Chemical Society. 123: 7831-41. PMID 11493056 DOI: 10.1021/Ja010059L  0.568
2001 Tanase T, Inukai H, Onaka T, Kato M, Yano S, Lippard SJ. Trinuclear Zn(II) and Cu(II) homo and heterotrimetallic complexes involving D-glucopyranosyl and biscarboxylate bridging ligands. A substrate binding model of xylose isomerases. Inorganic Chemistry. 40: 3943-53. PMID 11466052 DOI: 10.1021/Ic001419T  0.35
2001 Lee D, Lippard SJ. Oxidative N-dealkylation of a carboxylate-bridged diiron(II) precursor complex by reaction with O2 affords the elusive [Fe2(mu-OH)2(mu-O2CR)](3+) core of soluble methane monooxygenase hydroxylase. Journal of the American Chemical Society. 123: 4611-2. PMID 11457252 DOI: 10.1021/Ja0100930  0.667
2001 Gherman BF, Dunietz BD, Whittington DA, Lippard SJ, Friesner RA. Activation of the C-H bond of methane by intermediate Q of methane monooxygenase: a theoretical study. Journal of the American Chemical Society. 123: 3836-7. PMID 11457123 DOI: 10.1021/Ja0055108  0.504
2001 Whittington DA, Lippard SJ. Crystal structures of the soluble methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath) demonstrating geometrical variability at the dinuclear iron active site. Journal of the American Chemical Society. 123: 827-38. PMID 11456616 DOI: 10.1021/Ja003240N  0.371
2001 Franz KJ, Doerrer LH, Spingler B, Lippard SJ. Pentacoordinate cobalt(III) thiolate and nitrosyl tropocoronand compounds. Inorganic Chemistry. 40: 3774-80. PMID 11442376 DOI: 10.1021/Ic010181L  0.758
2001 Kaminskaia NV, Spingler B, Lippard SJ. Intermediate in beta-lactam hydrolysis catalyzed by a dinuclear zinc(II) complex: relevance to the mechanism of metallo-beta-lactamase. Journal of the American Chemical Society. 123: 6555-63. PMID 11439042 DOI: 10.1021/Ja002699E  0.572
2001 He C, DuBois JL, Hedman B, Hodgson KO, Lippard SJ. A Short Copper-Copper Distance in a (µ-1,2-Peroxo)dicopper(II) Complex Having a 1,8-Naphthyridine Unit as an Additional Bridge This work was supported by grants from the National Science Foundation and the National Institutes of Health. We thank A. M. Barrios for help in acquiring resonance Raman spectra. X-ray absorption spectroscopic data were measured at SSRL. SSRL is funded by the Department of Energy, Office of Basic Energy Science. The SSRL Structural Molecular Biology Program is supported by the National Institute of Health, National Center for Research Resources, Biomedical Technology Program, and by the Department of Energy, Office of Biological and Environmental Research. Angewandte Chemie (International Ed. in English). 40: 1484-1487. PMID 11317309 DOI: 10.1002/1521-3773(20010417)40:8<1484::AID-ANIE1484>3.0.CO;2-Z  0.474
2001 Barrios AM, Lippard SJ. Decomposition of alkyl-substituted urea molecules at a hydroxide-bridged dinickel center Inorganic Chemistry. 40: 1250-1255. PMID 11300826 DOI: 10.1021/Ic000933W  0.363
2001 Whittington DA, Rosenzweig AC, Frederick CA, Lippard SJ. Xenon and halogenated alkanes track putative substrate binding cavities in the soluble methane monooxygenase hydroxylase. Biochemistry. 40: 3476-82. PMID 11297413 DOI: 10.1021/Bi0022487  0.556
2001 He C, Lippard SJ. Synthesis and electrochemical studies of diiron complexes of 1,8-naphthyridine-based dinucleating ligands to model features of the active sites of non-heme diiron enzymes. Inorganic Chemistry. 40: 1414-20. PMID 11261945 DOI: 10.1021/Ic000975K  0.526
2001 Barrios AM, Lippard SJ. Phthalazine-based dinucleating ligands afford dinuclear centers often encountered in metalloenzyme active sites Inorganic Chemistry. 40: 1060-1064. PMID 11259020 DOI: 10.1021/Ic000889K  0.36
2001 Stahl SS, Francisco WA, Merkx M, Klinman JP, Lippard SJ. Oxygen kinetic isotope effects in soluble methane monooxygenase. The Journal of Biological Chemistry. 276: 4549-53. PMID 11073959 DOI: 10.1074/Jbc.M008301200  0.418
2001 Baik M, Lee D, Friesner RA, Lippard SJ. Theoretical studies of diiron(II) complexes that model features of the dioxygen-activating centers in non-heme diiron enzymes Israel Journal of Chemistry. 41: 173-186. DOI: 10.1560/8Yug-V7Ef-Vhhp-6Ug2  0.768
2001 Franz KJ, Lippard SJ. NO Disproportionation Reactivity of Fe Tropocoronand ComplexesJ. Am. Chem. Soc.1999,121, 10504−10512. Journal of the American Chemical Society. 123: 1266-1266. DOI: 10.1021/Ja0046665  0.559
2001 Spingler B, Scanavy-Grigorieff M, Werner A, Berke H, Lippard SJ. Crystal structure determination of a (μ-amido)(μ-hydroxo)(μ-superoxo)dicobalt(III)complex from the Werner collection Inorganic Chemistry. 40: 1065-1066. DOI: 10.1021/Ic001137T  0.594
2001 He C, Lippard SJ. ChemInform Abstract: Design and Synthesis of Multidentate Dinucleating Ligands Based on 1,8-Naphthyridine. Cheminform. 32: no-no. DOI: 10.1002/chin.200109134  0.332
2000 Franz KJ, Singh N, Spingler B, Lippard SJ. Aminotroponiminates as ligands for potential metal-based nitric oxide sensors. Inorganic Chemistry. 39: 4081-92. PMID 11198863 DOI: 10.1021/Ic000344Q  0.705
2000 He C, Gomez V, Spingler B, Lippard SJ. Monodentate-bridged phosphodiester and sulfate complexes: structural insights into the biological activation of phosphodiesters, sulfate, and sulfate esters. Inorganic Chemistry. 39: 4188-9. PMID 11196909 DOI: 10.1021/ic000391i  0.592
2000 Kaminskaia NV, He C, Lippard SJ. Reactivity of mu-hydroxodizinc(II) centers in enzymatic catalysis through model studies. Inorganic Chemistry. 39: 3365-73. PMID 11196876 DOI: 10.1021/Ic000169D  0.477
2000 Franz KJ, Lippard SJ. Nitrosyl transfer from manganese to iron in tropocoronand complexes. Inorganic Chemistry. 39: 3722-3. PMID 11196841 DOI: 10.1021/Ic000360N  0.599
2000 He C, Lippard SJ. Synthesis and characterization of several dicopper(I) complexes and a spin-delocalized dicopper(I,II) mixed-valence complex using a 1,8-naphthyridine-based dinucleating ligand. Inorganic Chemistry. 39: 5225-31. PMID 11154580 DOI: 10.1021/Ic0005339  0.482
2000 Ziegler CJ, Silverman AP, Lippard SJ. High-throughput synthesis and screening of platinum drug candidates. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 5: 774-83. PMID 11129005 DOI: 10.1007/S007750000170  0.539
2000 Burstyn JN, Heiger-Bernays WJ, Cohen SM, Lippard SJ. Formation of cis-diamminedichloroplatinum(II) 1,2-intrastrand cross-links on DNA is flanking-sequence independent. Nucleic Acids Research. 28: 4237-43. PMID 11058123 DOI: 10.1093/Nar/28.21.4237  0.654
2000 Cohen SM, Mikata Y, He Q, Lippard SJ. HMG-domain protein recognition of cisplatin 1,2-intrastrand d(GpG) cross-links in purine-rich sequence contexts. Biochemistry. 39: 11771-6. PMID 10995245 DOI: 10.1021/Bi001352L  0.475
2000 Franz KJ, Singh N, Lippard SJ. Metal-Based NO Sensing by Selective Ligand Dissociation This work was supported by a grant from the National Science Foundation and a fellowship to N.S. from the Undergraduate Research Opportunity Program (MIT). We thank Prof. Roger Tsien for valuable discussions at the inception of this project. Angewandte Chemie (International Ed. in English). 39: 2120-2122. PMID 10941035 DOI: 10.1002/1521-3773(20000616)39:12<2120::Aid-Anie2120>3.0.Co;2-M  0.538
2000 Jamieson ER, Lippard SJ. Stopped-flow fluorescence studies of HMG-domain protein binding to cisplatin-modified DNA. Biochemistry. 39: 8426-38. PMID 10913248 DOI: 10.1021/Bi000342H  0.31
2000 Cohen SM, Jamieson ER, Lippard SJ. Enhanced binding of the TATA-binding protein to TATA boxes containing flanking cisplatin 1,2-cross-links. Biochemistry. 39: 8259-65. PMID 10889034 DOI: 10.1021/Bi0004495  0.458
2000 Coufal DE, Blazyk JL, Whittington DA, Wu WW, Rosenzweig AC, Lippard SJ. Sequencing and analysis of the Mmethylococcus capsulatus (Bath) solublemethane monooxygenase genes. European Journal of Biochemistry / Febs. 267: 2174-85. PMID 10759840 DOI: 10.1046/J.1432-1327.2000.01210.X  0.56
2000 Lee D, Krebs C, Huynh BH, Hendrich MP, Lippard SJ. Valence-delocalized diiron(II,III) cores supported by carboxylate-only bridging ligands [11] Journal of the American Chemical Society. 122: 5000-5001. DOI: 10.1021/Ja994448F  0.679
2000 Kaminskaia NV, Spingler B, Lippard SJ. Hydrolysis of β-lactam antibiotics catalyzed by dinuclear zinc(II) complexes: Functional mimics of metallo-β-lactamases Journal of the American Chemical Society. 122: 6411-6422. DOI: 10.1021/Ja993704L  0.568
2000 He C, Lippard SJ. Modeling Carboxylate-Bridged Dinuclear Active Sites in Metalloenzymes Using a Novel Naphthyridine-Based Dinucleating Ligand Journal of the American Chemical Society. 122: 184-185. DOI: 10.1021/Ja993125G  0.443
2000 He C, Barrios AM, Lee D, Kuzelka J, Davydov RM, Lippard SJ. Diiron complexes of 1,8-naphthyridine-based dinucleating ligands as models for hemerythrin Journal of the American Chemical Society. 122: 12683-12690. DOI: 10.1021/Ja0026861  0.731
2000 Barrios AM, Lippard SJ. Interaction of urea with a hydroxide-bridged dinuclear nickel center: An alternative model for the mechanism of urease Journal of the American Chemical Society. 122: 9172-9177. DOI: 10.1021/Ja000202V  0.368
2000 He C, Lippard SJ. Design and Synthesis of Multidentate Dinucleating Ligands Based on 1,8-Naphthyridine Tetrahedron. 56: 8245-8252. DOI: 10.1016/S0040-4020(00)00748-1  0.474
2000 Du Bois J, Mizoguchi TJ, Lippard SJ. Understanding the dioxygen reaction chemistry of diiron proteins through synthetic modeling studies Coordination Chemistry Reviews. 200: 443-485. DOI: 10.1016/S0010-8545(00)00336-2  0.556
2000 Franz K, Singh N, Lippard S. NO-Erkennung durch einen Metallkomplex als Folge der selektiven Dissoziation eines Liganden Angewandte Chemie. 112: 2194-2197. DOI: 10.1002/1521-3757(20000616)112:12<2194::Aid-Ange2194>3.0.Co;2-J  0.495
1999 Wilker JJ, Lippard SJ. Methylation of Iron-Sulfur Complexes by Trimethyl Phosphate. Inorganic Chemistry. 38: 3569-3574. PMID 11671106 DOI: 10.1021/Ic9808899  0.611
1999 Ziegler CJ, Sandman KE, Liang CH, Lippard SJ. Toxicity of platinum(II) amino acid (N,O) complexes parallels their binding to DNA as measured in a new solid phase assay involving a fluorescent HMG1 protein construct readout. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 4: 402-11. PMID 10555574 DOI: 10.1007/S007750050326  0.592
1999 Gassner GT, Lippard SJ. Component interactions in the soluble methane monooxygenase system from Methylococcus capsulatus (Bath). Biochemistry. 38: 12768-85. PMID 10504247 DOI: 10.1021/Bi990841M  0.331
1999 LeCloux DD, Barrios AM, Lippard SJ. The reactivity of well defined diiron(III) peroxo complexes toward substrates: Addition to electrophiles and hydrocarbon oxidation Bioorganic and Medicinal Chemistry. 7: 763-772. PMID 10400329 DOI: 10.1016/S0968-0896(98)00270-3  0.368
1999 Walters KJ, Gassner GT, Lippard SJ, Wagner G. Structure of the soluble methane monooxygenase regulatory protein B. Proceedings of the National Academy of Sciences of the United States of America. 96: 7877-82. PMID 10393915 DOI: 10.1073/Pnas.96.14.7877  0.451
1999 Ohndorf UM, Rould MA, He Q, Pabo CO, Lippard SJ. Basis for recognition of cisplatin-modified DNA by high-mobility-group proteins. Nature. 399: 708-12. PMID 10385126 DOI: 10.1038/21460  0.313
1999 Jamieson ER, Jacobson MP, Barnes CM, Chow CS, Lippard SJ. Structural and kinetic studies of a cisplatin-modified DNA icosamer binding to HMG1 domain B Journal of Biological Chemistry. 274: 12346-12354. PMID 10212205 DOI: 10.1074/Jbc.274.18.12346  0.684
1999 Valentine AM, LeTadic-Biadatti MH, Toy PH, Newcomb M, Lippard SJ. Oxidation of ultrafast radical clock substrate probes by the soluble methane monooxygenase from Methylococcus capsulatus (Bath). The Journal of Biological Chemistry. 274: 10771-6. PMID 10196150 DOI: 10.1074/Jbc.274.16.10771  0.658
1999 Coufal DE, Tavares P, Pereira AS, Hyunh BH, Lippard SJ. Reactions of nitric oxide with the reduced non-heme diiron center of the soluble methane monooxygenase hydroxylase Biochemistry. 38: 4504-4513. PMID 10194372 DOI: 10.1021/Bi9823378  0.311
1999 Davydov R, Valentine AM, Komar-Panicucci S, Hoffman BM, Lippard SJ. An EPR study of the dinuclear iron site in the soluble methane monooxygenase from Methylococcus capsulatus (Bath) reduced by one electron at 77 K: the effects of component interactions and the binding of small molecules to the diiron(III) center. Biochemistry. 38: 4188-97. PMID 10194335 DOI: 10.1021/Bi982391O  0.756
1999 Steinhuebel DP, Lippard SJ. Synthesis and Characterization of (Aminotroponiminato)titanium(IV) Dialkyl Complexes:  Control of Reactivity by Ligand Design Organometallics. 18: 3959-3961. DOI: 10.1021/Om9904347  0.339
1999 Steinhuebel DP, Lippard SJ. Synthesis of Unsymmetrical Vicinal Diols Using Titanium Aminotroponiminate Alkyl Complexes Organometallics. 18: 109-111. DOI: 10.1021/Om980927W  0.351
1999 Steinhuebel DP, Lippard SJ. Synthesis of Unsymmetrical Diolate, Oxametallacyclopentene, Amido-Alkoxide and Thiolato-Alkoxide Complexes Using Dialkyl and Diaryl Titanium Aminotroponiminate Complexes:  A Route to Unsymmetrical Vicinal Diols Journal of the American Chemical Society. 121: 11762-11772. DOI: 10.1021/Ja992662Y  0.359
1999 Barrios AM, Lippard SJ. Amide hydrolysis effected by a hydroxo-bridged dinickel(II) complex: Insights into the mechanism of urease Journal of the American Chemical Society. 121: 11751-11757. DOI: 10.1021/Ja992447H  0.358
1999 Lee D, Du Bois J, Petasis D, Hendrich MP, Krebs C, Huynh BH, Lippard SJ. Formation of Fe(III)Fe(IV) species from the reaction between a diiron(II) complex and dioxygen: Relevance to ribonucleotide reductase intermediate X [12] Journal of the American Chemical Society. 121: 9893-9894. DOI: 10.1021/Ja9923686  0.749
1999 Matsuo H, Walters KJ, Teruya K, Tanaka T, Gassner GT, Lippard SJ, Kyogoku Y, Wagner G. Identification by NMR Spectroscopy of Residues at Contact Surfaces in Large, Slowly Exchanging Macromolecular Complexes Journal of the American Chemical Society. 121: 9903-9904. DOI: 10.1021/Ja991881G  0.435
1999 Franz KJ, Lippard SJ. NO disproportionation reactivity of Fe tropocoronand complexes Journal of the American Chemical Society. 121: 10504-10512. DOI: 10.1021/Ja991664F  0.635
1999 Valentine AM, Stahl SS, Lippard SJ. Mechanistic studies of the reaction of reduced methane monooxygenase hydroxylase with dioxygen and substrates Journal of the American Chemical Society. 121: 3876-3887. DOI: 10.1021/Ja9839522  0.711
1999 Franz KJ, Lippard SJ, Marlin D, Mascharak P. Disproportionation of nitric oxide promoted by a Mn tropocoronand Chemtracts. 12: 135-140. DOI: 10.1021/Ja981410E  0.603
1999 Mizoguchi TJ, Davydov RM, Lippard SJ. Structural and Spectroscopic Comparisons between (μ-Oxo)- and (μ-Hydroxo)bis(μ-carboxylato)diiron(III) Complexes That Contain All-Oxygen-Donor Ligands Inorganic Chemistry. 38: 4098-4103. DOI: 10.1021/Ic990303Y  0.425
1998 Gelasco A, Lippard SJ. NMR solution structure of a DNA dodecamer duplex containing a cis-diammineplatinum(II) d(GpG) intrastrand cross-link, the major adduct of the anticancer drug cisplatin. Biochemistry. 37: 9230-9. PMID 9649303 DOI: 10.1021/Bi973176V  0.73
1998 Zamble DB, Jacks T, Lippard SJ. p53-Dependent and -independent responses to cisplatin in mouse testicular teratocarcinoma cells Proceedings of the National Academy of Sciences of the United States of America. 95: 6163-6168. PMID 9600935 DOI: 10.1073/Pnas.95.11.6163  0.593
1998 Trimmer EE, Zamble DB, Lippard SJ, Essigmann JM. Human testis-determining factor SRY binds to the major DNA adduct of cisplatin and a putative target sequence with comparable affinities. Biochemistry. 37: 352-62. PMID 9425057 DOI: 10.1021/Bi971675Q  0.626
1998 Scott MJ, Lippard SJ. Synthesis and Reactivity of Cationic Group 4 Tropocoronand Complexes Organometallics. 17: 1769-1773. DOI: 10.1021/Om971126G  0.351
1998 Scott MJ, Lippard SJ. Reactivity of the Coordinated η2-Ketone in the Tropocoronand Complex [Hf(TC-3,5)(η2-OC(CH2Ph)2)]:  N−C Coupling, C−C Coupling, and Insertion into the C−O Bond Organometallics. 17: 466-474. DOI: 10.1021/Om971040N  0.329
1998 Lee D, Lippard SJ. Structural and functional models of the dioxygen-activating centers of non-heme diiron enzymes ribonucleotide reductase and soluble methane monooxygenase [15] Journal of the American Chemical Society. 120: 12153-12154. DOI: 10.1021/Ja9831094  0.602
1998 Zhang XX, Fuhrmann P, Lippard SJ. Synthesis and triiron complexes of PDK, a new porphyrin-linked dicarboxylate ligand Journal of the American Chemical Society. 120: 10260-10261. DOI: 10.1021/Ja9816990  0.349
1998 LeCloux DD, Barrios AM, Mizoguchi TJ, Lippard SJ. Modeling the diiron centers of non-heme iron enzymes. Preparation of sterically hindered diiron(II) tetracarboxylate complexes and their reactions with dioxygen Journal of the American Chemical Society. 120: 9001-9014. DOI: 10.1021/Ja981216S  0.422
1998 Willems JP, Valentine AM, Gurbiel R, Lippard SJ, Hoffman BM. Small molecule binding to the mixed-valent Diiron center of methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath) as revealed by ENDOR spectroscopy Journal of the American Chemical Society. 120: 9410-9416. DOI: 10.1021/Ja980795Y  0.708
1998 LeCloux DD, Davydov R, Lippard SJ. Synthesis and Characterization of Spin-Delocalized Carboxylate-Bridged Cu(I)−Cu(II) Mixed-Valence Complexes Having Only Oxygen Donor Ligands Journal of the American Chemical Society. 120: 6810-6811. DOI: 10.1021/Ja9805021  0.346
1998 Dunham SU, Turner CJ, Lippard SJ. Solution structure of a DNA duplex containing a nitroxide spin-labeled platinum d(GpG) intrastrand cross-link refined with NMR-derived long-range electron-proton distance restraints Journal of the American Chemical Society. 120: 5395-5406. DOI: 10.1021/Ja9742592  0.32
1998 Valentine AM, Tavares P, Pereira AS, Davydov R, Krebs C, Hoffman BM, Edmondson DE, Boi Hanh Huynh, Lippard SJ. Generation of a mixed-valent Fe(III)Fe(IV) form of intermediate Q in the reaction cycle of soluble methane monooxygenase, an analog of intermediate X in ribonucleotide reductase R2 assembly [10] Journal of the American Chemical Society. 120: 2190-2191. DOI: 10.1021/Ja974169X  0.73
1998 He C, Lippard SJ. Aminoguanidinium Hydrolysis Effected by a Hydroxo-Bridged Dicobalt(II) Complex as a Functional Model for Arginase and Catalyzed by Mononuclear Cobalt(II) Complexes Journal of the American Chemical Society. 120: 105-113. DOI: 10.1021/Ja972524D  0.506
1998 Bino A, Shweky I, Cohen S, Bauminger ER, Lippard SJ. A Novel Nonairon(III) Citrate Complex:  A “Ferric Triple-Decker” Inorganic Chemistry. 37: 5168-5172. DOI: 10.1021/Ic9715658  0.391
1998 Steinhuebel DP, Fuhrmann P, Lippard SJ. Synthesis, characterization, and reactivity of organometallic Zr(IV) carboxylate complexes Inorganica Chimica Acta. 270: 527-536. DOI: 10.1016/S0020-1693(97)06117-3  0.397
1998 Whittington DA, Valentine AM, Lippard SJ. Substrate binding and C-H bond activation in the soluble methane monooxygenase hydroxylase Journal of Biological Inorganic Chemistry. 3: 307-313. DOI: 10.1007/S007750050237  0.683
1998 Sandman KE, Fuhrmann P, Lippard SJ. A mechanism-based, solution-phase method for screening combinatorial mixtures anticancer drugs Journal of Biological Inorganic Chemistry. 3: 74-80. DOI: 10.1007/S007750050209  0.323
1997 Doerrer LH, Bautista MT, Lippard SJ. Tuning of Electronic Properties and Reactivity in Four-Coordinate Cobalt(III) Complexes by the Tetraazamacrocyclic Tropocoronand Ligand. Inorganic Chemistry. 36: 3578-3579. PMID 11670045 DOI: 10.1021/Ic9703235  0.654
1997 Wilker JJ, Wetterhahn KE, Lippard SJ. Methyl Transfer to Mercury Thiolates: Effects of Coordination Number and Ligand Dissociation. Inorganic Chemistry. 36: 2079-2083. PMID 11669826 DOI: 10.1021/Ic961178I  0.731
1997 Wilker JJ, Lippard SJ. Alkyl Transfer to Metal Thiolates: Kinetics, Active Species Identification, and Relevance to the DNA Methyl Phosphotriester Repair Center of Escherichia coli Ada. Inorganic Chemistry. 36: 969-978. PMID 11669658 DOI: 10.1021/Ic961082O  0.598
1997 Rosenzweig AC, Brandstetter H, Whittington DA, Nordlund P, Lippard SJ, Frederick CA. Crystal structures of the methane monooxygenase hydroxylase from Methylococcus capsulatus (Bath): implications for substrate gating and component interactions. Proteins. 29: 141-52. PMID 9329079 DOI: 10.1002/(Sici)1097-0134(199710)29:2<141::Aid-Prot2>3.0.Co;2-G  0.57
1997 Valentine AM, Lippard SJ. Principles of small molecule activation by metalloenzymes as exemplified by the soluble methane monooxygenase from Methylococcus capsulatus (Bath) Journal of the Chemical Society - Dalton Transactions. 3925-3931. DOI: 10.1039/A705116F  0.645
1997 Scott MJ, Lippard SJ. Isocyanide Insertion Reactions with Organometallic Group 4 Tropocoronand Complexes:  Formation of η2-Iminoacyl, Enediamido, η2-Imine, and μ-Imido Products Organometallics. 16: 5857-5868. DOI: 10.1021/Om9706830  0.306
1997 Klassen RB, Lippard SJ. Differences in the Reactivity of [Ag(PBu3)I]4and [Cu(PBu3)I]4in Promoting Conjugate Addition Organometallics. 16: 3623-3627. DOI: 10.1021/Om9700728  0.322
1997 Liu KE, Valentine AM, Qiu D, Edmondson DE, Appelman EH, Spiro TG, Lippard SJ. Characterization of a Diiron(III) Peroxo Intermediate in the Reaction Cycle of Methane Monooxygenase Hydroxylase fromMethylococcus capsulatus(Bath)J.Am.Chem.Soc.1995,117, 4997−4998 Journal of the American Chemical Society. 119: 11134-11135. DOI: 10.1021/Ja975423O  0.66
1997 Takahara PM, Frederick CA, Lippard SJ. Crystal Structure of the Anticancer Drug Cisplatin Bound to Duplex DNAJ.Am.Chem.Soc.1996,118, 12309−12321 Journal of the American Chemical Society. 119: 4795-4795. DOI: 10.1021/Ja975403M  0.761
1997 Scott MJ, Lippard SJ. Coupling of Carbon Monoxide to Isocyanides and Enones Induced by Alkyl Zr(IV) and Hf(IV) Tropocoronand Complexes Journal of the American Chemical Society. 119: 3411-3412. DOI: 10.1021/Ja9640861  0.308
1997 Valentine AM, Wilkinson B, Liu KE, Komar-Panicucci S, Priestley ND, Williams PG, Morimoto H, Floss HG, Lippard SJ. Tritiated chiral alkanes as substrates for soluble methane monooxygenase from Methylococcus capsulatus (Bath): Probes for the mechanism of hydroxylation Journal of the American Chemical Society. 119: 1818-1827. DOI: 10.1021/Ja963971G  0.638
1997 Herold S, Lippard SJ. Carboxylate-Bridged Diiron(II) Complexes:  Synthesis, Characterization, and O2-Reactivity of Models for the Reduced Diiron Centers in Methane Monooxygenase and Ribonucleotide Reductase Journal of the American Chemical Society. 119: 145-156. DOI: 10.1021/Ja9628563  0.425
1997 Feig AL, Masschelein A, Bakac A, Lippard SJ. Kinetic studies of reactions of dioxygen with carboxylate-bridged diiron(II) complexes leading to the formation of (μ-oxo)diiron(III) complexes Journal of the American Chemical Society. 119: 334-342. DOI: 10.1021/Ja962814E  0.733
1997 Doerrer LH, Lippard SJ. Zinc and Cadmium Tropocoronand Complexes:  Effect of Metal Ion Radius on Macrocyclic Ligand Twist and Fold Inorganic Chemistry. 36: 2554-2563. DOI: 10.1021/Ic970033O  0.611
1997 Herold S, Lippard SJ. Synthesis, Characterization, and Magnetic Studies of Two Novel Isostructural Pentanuclear Iron(II) Complexes Inorganic Chemistry. 36: 50-58. DOI: 10.1021/Ic960783I  0.371
1997 Zamble DB, Lippard SJ. Biological mechanisms of cisplatin cytotoxicity Journal of Inorganic Biochemistry. 67: 141. DOI: 10.1016/S0162-0134(97)80019-0  0.595
1997 Scott MJ, Lippard SJ. Synthesis and characterization of Zr(IV) and Hf(IV) tropocoronand complexes Inorganica Chimica Acta. 263: 287-299. DOI: 10.1016/S0020-1693(97)05652-1  0.38
1997 Watton SP, Fuhrmann P, Pence LE, Lippard SJ, Caneschi A, Cornia A, Abbati GL. A Cyclic Octadecairon(III) Complex, the Molecular 18-Wheeler Angewandte Chemie International Edition in English. 36: 2774-2776. DOI: 10.1002/Anie.199727741  0.687
1997 Watton SP, Fuhrmann P, Pence LE, Lippard SJ, Caneschi A, Cornia A, Abbati GL. Ein cyclischer Octadecaeisen(III)-Komplex: ein molekulares Achtzehner-Rad Angewandte Chemie. 109: 2917-2919. DOI: 10.1002/Ange.19971092430  0.673
1996 Feig AL, Bautista MT, Lippard SJ. A Carboxylate-Bridged Non-Heme Diiron Dinitrosyl Complex. Inorganic Chemistry. 35: 6892-6898. PMID 11666858 DOI: 10.1021/Ic960552B  0.732
1996 Jaynes BS, Doerrer LH, Liu S, Lippard SJ. Synthesis, Tuning of the Stereochemistry, and Physical Properties of Cobalt(II) Tropocoronand Complexes. Inorganic Chemistry. 35: 6630. PMID 11666816 DOI: 10.1021/Ic961041S  0.635
1996 Feig AL, Becker M, Schindler S, van Eldik R, Lippard SJ. Mechanistic Studies of the Formation and Decay of Diiron(III) Peroxo Complexes in the Reaction of Diiron(II) Precursors with Dioxygen. Inorganic Chemistry. 35: 2590-2601. PMID 11666474 DOI: 10.1021/Ic951242G  0.717
1996 Zamble DB, Mu D, Reardon JT, Sancar A, Lippard SJ. Repair of cisplatin-DNA adducts by the mammalian excision nuclease Biochemistry. 35: 10004-10013. PMID 8756462 DOI: 10.1021/Bi960453+  0.617
1996 Poklar N, Pilch DS, Lippard SJ, Redding EA, Dunham SU, Breslauer KJ. Influence of cisplatin intrastrand crosslinking on the conformation, thermal stability, and energetics of a 20-mer DNA duplex. Proceedings of the National Academy of Sciences of the United States of America. 93: 7606-11. PMID 8755522 DOI: 10.1073/Pnas.93.15.7606  0.307
1996 Kane SA, Lippard SJ. Photoreactivity of platinum(II) in cisplatin-modified DNA affords specific cross-links to HMG domain proteins. Biochemistry. 35: 2180-8. PMID 8652559 DOI: 10.1021/Bi952240A  0.365
1996 Takahara PM, Frederick CA, Lippard SJ. Crystal structure of the anticancer drug cisplatin bound to duplex DNA Journal of the American Chemical Society. 118: 12309-12321. DOI: 10.1021/Ja9625079  0.772
1996 Kim K, Lippard SJ. Structure and Mössbauer Spectrum of a (μ-1,2-Peroxo)bis(μ-carboxylato)diiron(III) Model for the Peroxo Intermediate in the Methane Monooxygenase Hydroxylase Reaction Cycle Journal of the American Chemical Society. 118: 4914-4915. DOI: 10.1021/Ja9604370  0.349
1996 DeRose VJ, Liu KE, Lippard SJ, Hoffman BM. Investigation of the Dinuclear Fe Center of Methane Monooxygenase by Advanced Paramagnetic Resonance Techniques:  On the Geometry of DMSO Binding Journal of the American Chemical Society. 118: 121-134. DOI: 10.1021/ja951108v  0.37
1996 Yun JW, Tanase T, Lippard SJ. Carboxylate- and Phosphate Ester-Bridged Dimagnesium(II), Dizinc(II), and Dicalcium(II) Complexes. Models for Intermediates in Biological Phosphate Ester Hydrolysis Inorganic Chemistry. 35: 7590-7600. DOI: 10.1021/Ic960894H  0.396
1996 Tanase T, Yun JW, Lippard SJ. Zinc-Containing Carboxylate-Bridged Heterodimetallic Complexes and Their Reactions with Phosphodiester Ligands Inorganic Chemistry. 35: 3585-3594. DOI: 10.1021/Ic951625E  0.339
1996 Caneschi A, Cornia A, Lippard SJ, Papaefthymiou GC, Sessoli R. Magnetic properties of dodecanuclear mixed valence iron clusters Inorganica Chimica Acta. 243: 295-304. DOI: 10.1016/0020-1693(95)04919-3  0.364
1995 Rosenzweig AC, Nordlund P, Takahara PM, Frederick CA, Lippard SJ. Geometry of the soluble methane monooxygenase catalytic diiron center in two oxidation states. Chemistry & Biology. 2: 409-18. PMID 9432288 DOI: 10.1016/1074-5521(95)90222-8  0.819
1995 Rosenzweig AC, Nordlund P, Takahara PM, Frederick CA, Lippard SJ. Geometry of the soluble methane monooxygenase catalytic diiron center in two oxidation states. Chemistry & Biology. 2: 409-18. PMID 9383443  0.82
1995 Zamble DB, Lippard SJ. Cisplatin and DNA repair in cancer chemotherapy Trends in Biochemical Sciences. 20: 435-439. PMID 8533159 DOI: 10.1016/S0968-0004(00)89095-7  0.605
1995 Chow CS, Barnes CM, Lippard SJ. A single HMG domain in high-mobility group 1 protein binds to DNAs as small as 20 base pairs containing the major cisplatin adduct Biochemistry. 34: 2956-2964. PMID 7893709 DOI: 10.1021/Bi00009A027  0.682
1995 Takahara PM, Rosenzweig AC, Frederick CA, Lippard SJ. Crystal structure of double-stranded DNA containing the major adduct of the anticancer drug cisplatin. Nature. 377: 649-52. PMID 7566180 DOI: 10.1038/377649A0  0.768
1995 Bronk BS, Protasiewicz JD, Pence LE, Lippard SJ. Reactions of Low-Valent Group V Dicarbonyl Phosphine Complexes with Carbon-Based Electrophiles To Produce Metal Alkyl, Acyl, Carbyne, and Acetylene Complexes Organometallics. 14: 2177-2187. DOI: 10.1021/Om960365L  0.7
1995 Bronk BS, Protasiewicz JD, Lippard SJ. Reductive Coupling of Group 5 Dicarbonyls to Disiloxyacetylene Complexes: Ring Formation and Effects of Increasing Steric Demands Organometallics. 14: 1385-1392. DOI: 10.1021/Om00003A044  0.686
1995 Liu KE, Valentine AM, Wang D, Huynh BH, Edmondson DE, Salifoglou A, Lippard SJ. Kinetic and spectroscopic characterization of intermediates and component interactions in reactions of methane monooxygenase from Methylococcus capsulatus (Bath) Journal of the American Chemical Society. 117: 10174-10185. DOI: 10.1021/Ja00146A002  0.665
1995 Wilker JJ, Lippard SJ. Modeling the DNA Methylphosphotriester Repair Site in Escherichia coli Ada. Why Zinc and Four Cysteines? Journal of the American Chemical Society. 117: 8682-8683. DOI: 10.1021/Ja00138A031  0.573
1995 Herold S, Pence LE, Lippard SJ. Carboxylate-Bridged Diiron(II) Complexes, Including a New Model for Reduced Methane Monooxygenase Hydroxylase and the R2 Protein of Ribonucleotide Reductase Journal of the American Chemical Society. 117: 6134-6135. DOI: 10.1021/Ja00127A032  0.34
1995 Goldberg DP, Caneschi A, Delfs CD, Sessoli R, Lippard SJ. A Decanuclear Manganese Cluster with Oxo and Halide Bridging Ligands: Magnetic Behavior of an S .gtoreq. 12 System Journal of the American Chemical Society. 117: 5789-5800. DOI: 10.1021/Ja00126A018  0.454
1995 Liu KE, Valentine AM, Qiu D, Edmondson DE, Appelman EH, Spiro TG, Lippard SJ. Characterization of a Diiron(III) Peroxide Intermediate in the Reaction Cycle of Methane Monooxygenase Hydroxylase from Methylococcus capsulatus (Bath) Journal of the American Chemical Society. 117: 4997-4998. DOI: 10.1021/Ja00122A032  0.662
1995 Yun JW, Tanase T, Pence LE, Lippard SJ. Carboxylate- and Phosphodiester-Bridged Dinuclear Magnesium(II) Complexes Journal of the American Chemical Society. 117: 4407-4408. DOI: 10.1021/Ja00120A027  0.371
1995 Goldberg DP, Koulougliotis D, Brudvig GW, Lippard SJ. A (.mu.-Oxo)bis(.mu.-carboxylato)diiron(III) Complex with a Tethered Phenoxyl Radical as a Model for the Active Site of the R2 protein of Ribonucleotide Reductase Journal of the American Chemical Society. 117: 3134-3144. DOI: 10.1021/Ja00116A018  0.507
1995 Elmroth SKC, Lippard SJ. Surface and Electrostatic Contributions to DNA-Promoted Reactions of Platinum(II) Complexes with Short Oligonucleotides: A Kinetic Study Inorganic Chemistry. 34: 5234-5243. DOI: 10.1021/Ic00125A024  0.338
1995 Acho JA, Ren T, Yun JW, Lippard SJ. Dimolybdenum(II) Calixarene Complexes: Synthesis, Structure, Raman Spectroscopy, and Bonding Inorganic Chemistry. 34: 5226-5233. DOI: 10.1021/Ic00125A023  0.61
1995 Tanase T, Lippard SJ. Dinuclear Manganese(II) Complexes with the {Mn2(.mu.-carboxylato)2}2+ Core and Their Transformation to (.mu.-Oxo)bis(.mu.-carboxylato)dimanganese(III) Complexes Inorganic Chemistry. 34: 4682-4690. DOI: 10.1021/Ic00122A027  0.361
1995 Tanase T, Yun JW, Lippard SJ. Mono- and Dinuclear Zinc Complexes of XDK, H2XDK = m-Xylenediamine Bis(Kemp's triacid imide), and Their Reaction with Phosphate Esters Inorganic Chemistry. 34: 4220-4229. DOI: 10.1021/Ic00120A030  0.321
1995 Goldberg DP, Telser J, Bastos CM, Lippard SJ. Ferromagnetic versus Antiferromagnetic Exchange in Five Structurally Analogous Carboxylate-Bridged Trinuclear Ferrous Complexes Inorganic Chemistry. 34: 3011-3024. DOI: 10.1021/Ic00115A032  0.528
1995 Acho JA, Doerrer LH, Lippard SJ. Pentamethylcyclopentadienyl and Cyclopentadienyl Tantalum and Niobium Calixarene Compounds and Their Water and Acetonitrile Inclusion Complexes Inorganic Chemistry. 34: 2542-2556. DOI: 10.1021/Ic00114A011  0.615
1995 DeWitt JG, Rosenzweig AC, Salifoglou A, Hedman B, Lippard SJ, Hodgson KO. X-ray Absorption Spectroscopic Studies of the Diiron Center in Methane Monooxygenase in the Presence of Substrate and the Coupling Protein of the Enzyme System Inorganic Chemistry. 34: 2505-2515. DOI: 10.1021/Ic00114A007  0.664
1995 Herold S, Lippard SJ. Modeling the active site of non-heme iron proteins: Synthesis and characterization of carboxylate-bridged diiron(II) complexes Journal of Inorganic Biochemistry. 59: 399. DOI: 10.1016/0162-0134(95)97497-E  0.379
1995 Rosenzweig AC, Nordlund P, Lippard SJ, Frederick CA. High resolution crystal structures of the hydroxylase protein of methane monooxygenase Journal of Inorganic Biochemistry. 59: 381. DOI: 10.1016/0162-0134(95)97479-A  0.534
1995 Takahara PM, Rosenzweig AC, Frederick CA, Lippard SJ. X-ray structure of a dodecamer duplex containing the major cisplatin d(GpG) intrastrand cross-link Journal of Inorganic Biochemistry. 59: 194. DOI: 10.1016/0162-0134(95)97300-F  0.761
1995 Wilker JJ, Lippard SJ. Why does the Escherichia coli Ada protein employ a [Zn(S-cysteine)4]2− site to repair DNA methylphosphotriester lesions? Journal of Inorganic Biochemistry. 59: 98. DOI: 10.1016/0162-0134(95)97208-8  0.577
1995 Watton SP, Davis MI, Pence LE, Rebek J, Lippard SJ. Alkali metal-responsive geometric and spectral changes in a cobalt(II) complex of a constrained dicarboxylate: a carboxylate shift-mediated metallochromoionophore Inorganica Chimica Acta. 235: 195-204. DOI: 10.1016/0020-1693(95)90061-A  0.689
1995 Acho JA, Lippard SJ. Calixarene complexes of the molybdenum-molybdenum quadruple bond Inorganica Chimica Acta. 229: 5-8. DOI: 10.1016/0020-1693(94)04264-V  0.358
1995 Caneschi A, Cornia A, Lippard SJ. A Cyclic Hexairon(III) Complex with an Octahedrally Coordinated Sodium Ion at the Center, an Example of the[12]Metallacrown-6 Structure Type Angewandte Chemie International Edition in English. 34: 467-469. DOI: 10.1002/Anie.199504671  0.34
1994 Bender CJ, Rosenzweig AC, Lippard SJ, Peisach J. Nuclear hyperfine coupling of nitrogen in the coordination sphere of the diiron center of methane monooxygenase hydroxylase. The Journal of Biological Chemistry. 269: 15993-8. PMID 8206895  0.551
1994 Chow CS, Whitehead JP, Lippard SJ. HMG domain proteins induce sharp bends in cisplatin-modified DNA. Biochemistry. 33: 15124-30. PMID 7999772 DOI: 10.1021/Bi00254A023  0.681
1994 Huang JC, Zamble DB, Reardon JT, Lippard SJ, Sancar A. HMG-domain proteins specifically inhibit the repair of the major DNA adduct of the anticancer drug cisplatin by human excision nuclease. Proceedings of the National Academy of Sciences of the United States of America. 91: 10394-8. PMID 7937961 DOI: 10.1073/Pnas.91.22.10394  0.612
1994 Protasiewicz JD, Bronk BS, Masschelein A, Lippard SJ. Electrophile-Promoted Carbyne-CO Coupling at a Tantalum Center Organometallics. 13: 1300-1311. DOI: 10.1021/Om00016A037  0.659
1994 Tanase T, Watton SP, Lippard SJ. Carboxylate-Bridged Heterodimetallic Complexes Journal of the American Chemical Society. 116: 9401-9402. DOI: 10.1021/Ja00099A096  0.686
1994 Feig AL, Lippard SJ. Mechanistic Studies of the Reaction of Dioxygen with Dinuclear Iron(II) Compounds to Form (.mu.-Peroxo)diiron(III) Complexes Journal of the American Chemical Society. 116: 8410-8411. DOI: 10.1021/Ja00097A076  0.732
1994 Micklitz W, McKee V, Rardin RL, Pence LE, Papaefthymiou GC, Bott SG, Lippard SJ. Polyiron Oxo Chemistry at the Molecular/Solid-State Boundary: Synthesis, Structure, and Magnetic and Moessbauer Properties of [Fe16MO10(OH)10(O2CPh)20] Complexes, M = Mn, Fe, or Co Journal of the American Chemical Society. 116: 8061-8069. DOI: 10.1021/Ja00097A012  0.667
1994 Hoffman BM, Sturgeon BE, Doan PE, DeRose VJ, Liu KE, Lippard SJ. ESEEM and ENDOR Magnetic Resonance Studies of the Non-Kramers Doublet in the Integer-Spin Diiron(II) Forms of Two Methane Monooxygenase Hydroxylases and Hemerythrin Azide Journal of the American Chemical Society. 116: 6023-6024. DOI: 10.1021/Ja00092A085  0.424
1994 Watton SP, Masschelein A, Rebek JJ, Lippard SJ. Synthesis, Structure, and Reactivity of (.mu.-Oxo)bis(.mu.-carboxylato)diiron(III) Complexes of a Dinucleating Dicarboxylate Ligand, a Kinetically Stable Model for Non-Heme Diiron Protein Cores Journal of the American Chemical Society. 116: 5196-5205. DOI: 10.1021/Ja00091A025  0.708
1994 Taft KL, Delfs CD, Papaefthymiou GC, Foner S, Gatteschi D, Lippard SJ. [Fe(OMe)2(O2CCH2Cl)]10, a Molecular Ferric Wheel Journal of the American Chemical Society. 116: 823-832. DOI: 10.1021/Ja00082A001  0.384
1994 Shweky I, Bino A, Goldberg DP, Lippard SJ. Syntheses, Structures, and Magnetic Properties of Two Dinuclear Iron(III) Citrate Complexes Inorganic Chemistry. 33: 5161-5162. DOI: 10.1021/Ic00101A001  0.525
1994 Taft KL, Papaefthymiou GC, Lippard SJ. Synthesis, Structure, and Electronic Properties of a Mixed-Valent Dodecairon Oxo Complex, a Model for the Biomineralization of Ferritin Inorganic Chemistry. 33: 1510-1520. DOI: 10.1021/Ic00085A049  0.409
1994 Turowski PN, Armstrong WH, Liu S, Brown SN, Lippard SJ. Synthesis and characterization of hydroxo-bridged diiron(III) complexes containing carboxylate or phosphate ester bridges: comparisons to diiron(III) proteins Inorganic Chemistry. 33: 636-645. DOI: 10.1021/Ic00082A006  0.621
1994 Feig AL, Lippard SJ. Reactions of Non-Heme Iron(II) Centers with Dioxygen in Biology and Chemistry Chemical Reviews. 94: 759-805. DOI: 10.1021/Cr00027A011  0.716
1994 Rosenzweig AC, Lippard SJ. Determining the Structure of a Hydroxylase Enzyme That Catalyzes the Conversion of Methane to Methanol in Methanotrophic Bacteria Accounts of Chemical Research. 27: 229-236. DOI: 10.1021/Ar00044A003  0.567
1994 Rosenzweig AC, Lippard SJ. Chemical nature of the hydroxylase enzyme of methane monooxygenase as revealed by the 2.2 Å crystal structure Chemistry and Biology. 1: xxii-xxiii. DOI: 10.1016/1074-5521(94)90028-0  0.541
1993 Taft KL, Papaefthymiou GC, Lippard SJ. A mixed-valent polyiron oxo complex that models the biomineralization of the ferritin core. Science (New York, N.Y.). 259: 1302-5. PMID 8446898 DOI: 10.1126/Science.8446898  0.348
1993 Pil PM, Chow CS, Lippard SJ. High-mobility-group 1 protein mediates DNA bending as determined by ring closures Proceedings of the National Academy of Sciences of the United States of America. 90: 9465-9469. PMID 8415724 DOI: 10.1073/Pnas.90.20.9465  0.68
1993 Rosenzweig AC, Frederick CA, Lippard SJ, Nordlund P. Crystal structure of a bacterial non-haem iron hydroxylase that catalyses the biological oxidation of methane. Nature. 366: 537-43. PMID 8255292 DOI: 10.1038/366537A0  0.581
1993 Taft KL, Caneschi A, Pence LE, Delfs CD, Papaefthymiou GC, Lippard SJ. Iron and manganese alkoxide cubes Journal of the American Chemical Society. 115: 11753-11766. DOI: 10.1021/Ja00078A014  0.382
1993 Ren T, Bancroft DP, Sundquist WI, Masschelein A, Keck MV, Lippard SJ. Synthesis, characterization, DNA binding properties, and solution thermochromism of platinum(II) complexes of the ethidium cation: regiospecificity in a DNA-promoted reaction Journal of the American Chemical Society. 115: 11341-11352. DOI: 10.1021/Ja00077A037  0.597
1993 Goldberg DP, Caneschi A, Lippard SJ. A decanuclear mixed-valent manganese complex with a high spin multiplicity in the ground state Journal of the American Chemical Society. 115: 9299-9300. DOI: 10.1021/Ja00073A060  0.455
1993 DeRose VJ, Liu KE, Kurtz DM, Hoffman BM, Lippard SJ. Proton ENDOR identification of bridging hydroxide ligands in mixed-valent diiron centers of proteins: methane monooxygenase and semimet azidohemerythrin Journal of the American Chemical Society. 115: 6440-6441. DOI: 10.1021/Ja00067A081  0.475
1993 Jaynes BS, Ren T, Masschelein A, Lippard SJ. Stereochemical control of reactivity in cobalt(III) alkyl complexes of the tropocoronand ligand system Journal of the American Chemical Society. 115: 5589-5599. DOI: 10.1021/Ja00066A027  0.623
1993 Goldberg DP, Watton SP, Masschelein A, Wimmer L, Lippard SJ. Complexes of a pendant phenoxyl radical ligand, including a new model for the ribonucleotide reductase R2 protein Journal of the American Chemical Society. 115: 5346-5347. DOI: 10.1021/Ja00065A077  0.72
1993 Protasiewicz JD, Masschelein A, Lippard SJ. Kinetic, spectroscopic, and structural evidence for carbene-carbyne intermediates in carbyne/CO coupling Journal of the American Chemical Society. 115: 808-810. DOI: 10.1021/Ja00055A074  0.681
1993 Beer RH, Lippard SJ. Carbon-13 NMR spectra of carboxylate-bridged paramagnetic dinuclear and tetranuclear iron oxo complexes Inorganic Chemistry. 32: 1030-1032. DOI: 10.1021/Ic00058A045  0.703
1993 Carnahan EM, Protasiewicz JD, Lippard SJ. The 15 years of reductive coupling: what have we learned? Accounts of Chemical Research. 26: 90-97. DOI: 10.1021/Ar00027A003  0.644
1993 DeRose V, Liu K, Kurtz D, Lippard S, Hoffman B. ENDOR identification of bridging hydroxide ligands in the mixed-valent diiron centers of methane monooxygenase and hemerythrin Journal of Inorganic Biochemistry. 51: 495. DOI: 10.1016/0162-0134(93)85523-B  0.48
1993 Goldberg D, Caneschi A, Lippard S. Synthesis and magnetochemistry of a new decanuclear manganese complex. Journal of Inorganic Biochemistry. 51: 486. DOI: 10.1016/0162-0134(93)85514-9  0.498
1993 Taft K, Papaefthymiou G, Sessoli R, Delfs C, Gatteschi D, Lippard S. Polynuclear iron complexes: Three new structural types. Journal of Inorganic Biochemistry. 51: 484. DOI: 10.1016/0162-0134(93)85512-7  0.326
1993 Chow CS, Lippard SJ. Recognition of cisplatin-modified DNA by proteins with HMG-box domains Journal of Inorganic Biochemistry. 51: 392. DOI: 10.1016/0162-0134(93)85421-4  0.666
1993 Lippard SJ. Oxygen activation by non-heme iron complexes and proteins Journal of Inorganic Biochemistry. 51: 279. DOI: 10.1016/0162-0134(93)85311-U  0.314
1993 Feig A, Masschelein A, Lippard S. Kinetic studies on the reaction of dioxygen with diiron(II) compounds - models for the active sites of non-heme iron enzymes Journal of Inorganic Biochemistry. 51: 258. DOI: 10.1016/0162-0134(93)85292-G  0.705
1993 Watton SP, Davis MI, Pence LE, Masschelein A, Rebek J, Lippard SJ. Dinuclear transition metal complexes of constrained carboxylate ligands Journal of Inorganic Biochemistry. 51: 152. DOI: 10.1016/0162-0134(93)85188-E  0.672
1993 Rosenzweig A, Nordlund P, Frederick C, Lippard S. X-ray crystallographic studies of the hydroxylase component of methane monooxygenase from Methylococcus capsulatus (Bath) Journal of Inorganic Biochemistry. 51: 151. DOI: 10.1016/0162-0134(93)85187-D  0.519
1992 Pil PM, Lippard SJ. Specific binding of chromosomal protein HMG1 to DNA damaged by the anticancer drug cisplatin. Science (New York, N.Y.). 256: 234-7. PMID 1566071 DOI: 10.1126/Science.1566071  0.301
1992 Rosenzweig AC, Frederick CA, Lippard SJ. Crystallization and preliminary X-ray analysis of the methane monooxygenase hydroxylase protein from Methylococcus capsulatus (Bath). Journal of Molecular Biology. 227: 583-5. PMID 1404375 DOI: 10.1016/0022-2836(92)90913-5  0.556
1992 Comess KM, Burstyn JN, Essigmann JM, Lippard SJ. Replication inhibition and translesion synthesis on templates containing site-specifically placed cis-diamminedichloroplatinum(II) DNA adducts. Biochemistry. 31: 3975-90. PMID 1314653 DOI: 10.1021/Bi00131A013  0.626
1992 Vrtis RN, Bott SG, Lippard SJ. Linear carbonyl-bridged, dinuclear tantalum siloxycarbyne complexes Organometallics. 11: 270-277. DOI: 10.1021/Om00037A049  0.329
1992 Jaynes BS, Ren T, Liu S, Lippard SJ. Tuning the stereochemistry of pentacoordinate cobalt(III) halide complexes: a rare case of trigonal bipyramidal stereochemistry for cobalt(III) Journal of the American Chemical Society. 114: 9670-9671. DOI: 10.1021/Ja00050A063  0.609
1992 Hartwig JF, Pil PM, Lippard SJ. Synthesis and DNA binding properties of a cisplatin analog containing a tethered dansyl group Journal of the American Chemical Society. 114: 8292-8293. DOI: 10.1021/Ja00047A051  0.457
1992 Hartwig JF, Lippard SJ. DNA binding properties of [Pt(NH3)(C6H11NH2)Cl2], a metabolite of an orally active platinum anticancer drug Journal of the American Chemical Society. 114: 5646-5654. DOI: 10.1021/Ja00040A026  0.493
1992 Rardin RL, Poganiuch P, Bino A, Goldberg DP, Tolman WB, Liu S, Lippard SJ. Synthesis and characterization of novel trinuclear iron(II) and manganese(II) carboxylate complexes: structural trends in low valent iron and manganese carboxylates Journal of the American Chemical Society. 114: 5240-5249. DOI: 10.1021/Ja00039A041  0.788
1992 Carnahan EM, Lippard SJ. Formation of highly functionalized metal-bound acetylenes by reductive coupling of carbon monoxide and methyl isocyanide ligands Journal of the American Chemical Society. 114: 4166-4174. DOI: 10.1021/Ja00037A019  0.341
1992 Keck MV, Lippard SJ. Unwinding of supercoiled DNA by platinum-ethidium and related complexes Journal of the American Chemical Society. 114: 3386-3390. DOI: 10.1021/Ja00035A033  0.344
1992 Carnahan EM, Rardin RL, Bott SG, Lippard SJ. Synthesis and characterization of seven-coordinate tantalum(I) and niobium(I) complexes with cis carbonyl and alkyl isocyanide ligands Inorganic Chemistry. 31: 5193-5201. DOI: 10.1021/Ic00051A009  0.666
1992 Protasiewicz JD, Bianconi PA, Williams ID, Liu S, Rao CP, Lippard SJ. Synthesis and structural characterization of low-valent Group V phosphine complexes Inorganic Chemistry. 31: 4134-4142. DOI: 10.1021/Ic00046A027  0.796
1992 Yu SB, Lippard SJ, Shweky I, Bino A. Dinuclear manganese(II) complexes with water and carboxylate bridges Inorganic Chemistry. 31: 3502-3504. DOI: 10.1021/Ic00043A004  0.341
1992 Taft KL, Masschelein A, Liu S, Lippard SJ, Garfinkel-Shweky D, Bino A. Models of the oxidized forms of polyiron oxo proteins: synthetic routes to (μ-oxo)bis(μ-carboxylato)diiron(III) complexes with neutral monodentate and bidentate capping ligands Inorganica Chimica Acta. 198: 627-631. DOI: 10.1016/S0020-1693(00)92407-1  0.436
1992 Costello CE, Comess KM, Plaziak AS, Bancroft DP, Lippard SJ. Fast atom bombardment and high performance tandem mass spectrometry of platinum(II) oligodeoxyribonucleotide fragments International Journal of Mass Spectrometry and Ion Processes. 122: 255-279. DOI: 10.1016/0168-1176(92)87020-F  0.309
1991 Feng XD, Bott SG, Lippard SJ. Structure of tetramethyl reductic acid (TMRA, 4,4,5,5-tetramethyl-2,3-dihydroxy-2-cyclopenten-1-one), a reductate ligand involved in dioxygen activation by multinuclear iron complexes. Acta Crystallographica. Section C, Crystal Structure Communications. 1671-4. PMID 2088419 DOI: 10.1107/S0108270189011868  0.302
1991 Hollis LS, Sundquist WI, Burstyn JN, Heiger-Bernays WJ, Bellon SF, Ahmed KJ, Amundsen AR, Stern EW, Lippard SJ. Mechanistic studies of a novel class of trisubstituted platinum(II) antitumor agents. Cancer Research. 51: 1866-75. PMID 2004370  0.625
1991 Carnahan EM, Lippard SJ. Mechanistic studies of the reductive coupling of isocyanides in seven-co-ordinate molybdenum complexes; X-ray crystal structures of [Mo(CNBut)6] and [Mo{CN(But)(SiMe2But)}(CNBut)5][O3SCF3] Journal of the Chemical Society-Dalton Transactions. 699-706. DOI: 10.1039/Dt9910000699  0.367
1991 Vrtis RN, Bott SG, Rardin RL, Lippard SJ. Reaction chemistry of [M(R3SiOCCOSiR3)(dmpe)2Cl] (M = tantalum, niobium): isolation and structural characterization of the first (dihydroxyacetylene)metal complexes and removal of the disiloxyacetylene ligand as an alkene Organometallics. 10: 1364-1373. DOI: 10.1021/Om00051A029  0.662
1991 Vrtis RN, Liu S, Rao CP, Bott SG, Lippard SJ. Mechanistic studies of the reductive coupling of carbon monoxide in seven-coordinate niobium(I) and tantalum(I) dicarbonyl complexes Organometallics. 10: 275-285. DOI: 10.1021/Om00047A061  0.584
1991 DeWitt JG, Bentsen JG, Rosenzweig AC, Hedman B, Green J, Pilkington S, Papaefthymiou GC, Dalton H, Hodgson KO, Lippard SJ. X-ray absorption, Moessbauer, and EPR studies of the dinuclear iron center in the hydroxylase component of methane monooxygenase Journal of the American Chemical Society. 113: 9219-9235. DOI: 10.1021/Ja00024A031  0.629
1991 Protasiewicz JD, Lippard SJ. Vanadium-promoted reductive coupling of carbon monoxide and facile hydrogenation to form cis-disiloxyethylenes Journal of the American Chemical Society. 113: 6564-6570. DOI: 10.1021/Ja00017A030  0.661
1991 Poganiuch P, Liu S, Papaefthymiou GC, Lippard SJ. Trinuclear, oxo-centered mixed-valence iron complex with unprecedented carboxylate coordination: [Fe3O(O2CCH3)6(TACN)].cntdot.2CHCl3 Journal of the American Chemical Society. 113: 4645-4651. DOI: 10.1021/Ja00012A037  0.356
1991 Tolman WB, Liu S, Bentsen JG, Lippard SJ. Models of the reduced forms of polyiron-oxo proteins: an asymmetric, triply carboxylate bridged diiron(II) complex and its reaction with dioxygen Journal of the American Chemical Society. 113: 152-164. DOI: 10.1021/Ja00001A023  0.567
1991 Beer RH, Tolman WB, Bott SG, Lippard SJ. Effects of a bridging dicarboxylate ligand on the synthesis and physical properties of (.mu.-oxo)bis(.mu.-carboxylato)diiron(III) complexes Inorganic Chemistry. 30: 2082-2092. DOI: 10.1021/Ic00009A026  0.774
1991 Gorun SM, Lippard SJ. Magnetostructural correlations in magnetically coupled (.mu.-oxo)diiron(III) complexes Inorganic Chemistry. 30: 1625-1630. DOI: 10.1021/Ic00007A038  0.635
1991 Warner S, Cheatham LK, Tulip TH, Williams ID, Lippard SJ. Synthesis and structure of seven-coordinate rhenium(III) mixed halo-phosphine isocyanide complexes Inorganic Chemistry. 30: 1221-1226. DOI: 10.1021/Ic00006A012  0.507
1991 Lippard SJ. Polyiron centers in methane monooxygenase and model complexes Journal of Inorganic Biochemistry. 43: 527. DOI: 10.1016/0162-0134(91)84502-Z  0.309
1990 Bellon SF, Lippard SJ. Bending studies of DNA site-specifically modified by cisplatin, trans-diamminedichloroplatinum(II) and cis-[Pt(NH3)2(N3-cytosine)Cl]+. Biophysical Chemistry. 35: 179-88. PMID 2397272 DOI: 10.1016/0301-4622(90)80007-T  0.308
1990 Donahue BA, Augot M, Bellon SF, Treiber DK, Toney JH, Lippard SJ, Essigmann JM. Characterization of a DNA damage-recognition protein from mammalian cells that binds specifically to intrastrand d(GpG) and d(ApG) DNA adducts of the anticancer drug cisplatin. Biochemistry. 29: 5872-80. PMID 2383564 DOI: 10.1021/Bi00476A032  0.325
1990 Comess KM, Costello CE, Lippard SJ. Identification and characterization of a novel linkage isomerization in the reaction of trans-diamminedichloroplatinum(II) with 5′-d(TCTACGCGTTCT) Biochemistry®. 2102-2110. PMID 2328242 DOI: 10.1021/Bi00460A020  0.325
1990 Coll M, Sherman SE, Gibson D, Lippard SJ, Wang AH. Molecular structure of the complex formed between the anticancer drug cisplatin and d(pGpG): C222(1) crystal form. Journal of Biomolecular Structure & Dynamics. 8: 315-30. PMID 2268406 DOI: 10.1080/07391102.1990.10507808  0.625
1990 Heiger-Bernays WJ, Essigmann JM, Lippard SJ. Effect of the antitumor drug cis-diamminedichloroplatinum(II) and related platinum complexes on eukaryotic DNA replication. Biochemistry. 29: 8461-6. PMID 2174701 DOI: 10.1021/Bi00488A037  0.307
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