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Dale Gene Drueckhammer - Publications

Affiliations: 
Stony Brook University, Stony Brook, NY, United States 
Area:
organic chemistry
Website:
http://www.chem.stonybrook.edu/faculty/drueckhammer.shtml

39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Liao J, Drueckhammer DG. Diastereoselective conjugate addition/cyclization/bromination: Access to four stereocenters in a single step Tetrahedron Letters. 59: 1776-1778. DOI: 10.1016/J.Tetlet.2018.03.080  0.367
2014 Liang X, Drueckhammer DG. Arsinous acid as a thiol binding group: Potential cysteine peptide tagging functionality that binds a single thiol New Journal of Chemistry. 38: 1368-1371. DOI: 10.1039/C3Nj01462B  0.333
2010 Zhu Y, Drueckhammer DG. ChemInform Abstract: An Efficient Synthesis of Geminal Di-Sulfones. Cheminform. 33: no-no. DOI: 10.1002/chin.200223072  0.441
2010 MARTIN DP, BIBART RT, DRUECKHAMMER DG. ChemInform Abstract: Synthesis of Novel Analogues of Acetyl Coenzyme A: Mimics of Enzyme Reaction Intermediates. Cheminform. 25: no-no. DOI: 10.1002/chin.199443272  0.328
2007 Wang J, Zheng X, Yang Y, Drueckhammer D, Yang W, Verkhivker G, Wang E. Quantifying intrinsic specificity: a potential complement to affinity in drug screening. Physical Review Letters. 99: 198101. PMID 18233118 DOI: 10.1103/Physrevlett.99.198101  0.532
2007 Lin C, Simov V, Drueckhammer DG. Interaction of halide and carboxylate ions with 4,5-diacetamidoacridine-9(10H)-one: thermodynamics of association and deprotonation events. The Journal of Organic Chemistry. 72: 1742-6. PMID 17286443 DOI: 10.1021/Jo062467J  0.43
2006 Huang H, Drueckhammer DG. A modular molecular tweezer designed using CAVEAT. Chemical Communications (Cambridge, England). 2995-7. PMID 16832515 DOI: 10.1039/B605756J  0.507
2006 Lin C, Drueckhammer DG. Computer-guided design of a Cu(II) receptor and sensor New Journal of Chemistry. 30: 1725-1730. DOI: 10.1039/B610887C  0.412
2005 Yang Y, Nesterenko DV, Trump RP, Yamaguchi K, Bartlett PA, Drueckhammer DG. Virtual hydrocarbon and combinatorial databases for use with CAVEAT. Journal of Chemical Information and Modeling. 45: 1820-3. PMID 16309289 DOI: 10.1021/Ci050277O  0.501
2005 Huang H, Drueckhammer DG. A computer-designed macrocyclic zinc receptor. Chemical Communications (Cambridge, England). 5196-8. PMID 16228033 DOI: 10.1039/B508542J  0.506
2005 Zhu Y, Drueckhammer DG. Transition state modeling and catalyst design for hydrogen bond-stabilized enolate formation. The Journal of Organic Chemistry. 70: 7755-60. PMID 16149809 DOI: 10.1021/Jo0513818  0.515
2005 Xun J, Huang H, Vogel KW, Drueckhammer DG. The importance of the amide bond nearest the thiol group in enzymatic reactions of coenzyme A. Bioorganic Chemistry. 33: 90-107. PMID 15788165 DOI: 10.1016/J.Bioorg.2004.10.002  0.658
2003 Yang W, Drueckhammer DG. Computational study of the citrate synthase catalyzed deprotonation of acetyl-coenzyme A and fluoroacetyl-coenzyme A: Demonstration of a layered quantum mechanical approach Journal of Physical Chemistry B. 107: 5986-5994. DOI: 10.1021/Jp034717V  0.312
2002 Beaman TW, Vogel KW, Drueckhammer DG, Blanchard JS, Roderick SL. Acyl group specificity at the active site of tetrahydridipicolinate N-succinyltransferase. Protein Science : a Publication of the Protein Society. 11: 974-9. PMID 11910040 DOI: 10.1110/Ps.4310102  0.34
2002 Zhu Y, Drueckhammer DG. An efficient synthesis of geminal di-sulfones Tetrahedron Letters. 43: 1377-1379. DOI: 10.1016/S0040-4039(02)00023-0  0.511
2001 Yang W, Drueckhammer DG. Understanding the relative acyl-transfer reactivity of oxoesters and thioesters: computational analysis of transition state delocalization effects. Journal of the American Chemical Society. 123: 11004-9. PMID 11686705 DOI: 10.1021/Ja010726A  0.31
2000 Mishra PK, Drueckhammer DG. Coenzyme A Analogues and Derivatives: Synthesis and Applications as Mechanistic Probes of Coenzyme A Ester-Utilizing Enzymes. Chemical Reviews. 100: 3283-3310. PMID 11777425 DOI: 10.1021/Cr990010M  0.406
2000 Yang W, Drueckhammer DG. Computational studies of the aminolysis of oxoesters and thioesters in aqueous solution Organic Letters. 2: 4133-6. PMID 11150182 DOI: 10.1021/Ol006691L  0.312
2000 Vogel KW, Stark LM, Mishra PK, Yang W, Drueckhammer DG. Investigating the role of the geminal dimethyl groups of coenzyme A: synthesis and studies of a didemethyl analogue. Bioorganic & Medicinal Chemistry. 8: 2451-60. PMID 11058040 DOI: 10.1016/S0968-0896(00)00189-9  0.374
2000 Mishra PK, Drueckhammer DG. ChemInform Abstract: Coenzyme A Analogues and Derivatives: Synthesis and Applications as Mechanistic Probes of Coenzyme A Ester-Utilizing Enzymes Cheminform. 31: no-no. DOI: 10.1002/chin.200051278  0.308
1999 Bibart RT, Vogel KW, Drueckhammer DG. Development of a Second Generation Coenzyme A Analogue Synthon. The Journal of Organic Chemistry. 64: 2903-2909. PMID 11674364 DOI: 10.1021/Jo981758S  0.421
1998 Mishra PK, Drueckhammer DG. Novel cofactor derivatives and cofactor-based models. Current Opinion in Chemical Biology. 2: 758-65. PMID 9914186 DOI: 10.1016/S1367-5931(98)80114-2  0.383
1998 Vogel KW, Drueckhammer DG. A reversed thioester analogue of acetyl-coenzyme A: An inhibitor of thiolase and a synthon for other acyl-CoA analogues Journal of the American Chemical Society. 120: 3275-3283. DOI: 10.1021/Ja971758U  0.325
1997 Kurz LC, Roble JH, Nakra T, Drysdale GR, Buzan JM, Schwartz B, Drueckhammer DG. Ability of single-site mutants of citrate synthase to catalyze proton transfer from the methyl group of dethiaacetyl-coenzyme A, a non-thioester substrate analog. Biochemistry. 36: 3981-90. PMID 9092828 DOI: 10.1021/Bi963058S  0.328
1996 Duncan R, Drueckhammer DG. Preparation of Deoxy Sugars via Aldolase-Catalyzed Synthesis of 1-Deoxy-1-thioketoses. The Journal of Organic Chemistry. 61: 438-439. PMID 11666955 DOI: 10.1021/Jo9520093  0.385
1996 Schwartz B, Vogel KW, Drueckhammer DG. Coenzyme A hemithioacetals as easily prepared inhibitors of CoA ester-utilizing enzymes Journal of Organic Chemistry. 61: 9356-9361. DOI: 10.1021/Jo9616724  0.385
1995 Duncan R, Drueckhammer DG. A pseudoisomerization route to aldose sugars using aldolase catalysis Journal of Organic Chemistry. 60: 7394-7395. DOI: 10.1021/Jo00128A008  0.319
1995 Tan DS, Günter MM, Drueckhammer DG. Enzymatic resolution coupled with substrate racemization using a thioester substrate Journal of the American Chemical Society. 117: 9093-9094. DOI: 10.1021/Ja00140A037  0.484
1994 Darrow JW, Drueckhammer DG. Cyclic phosphonate analogs of hexopyranoses Journal of Organic Chemistry. 59: 2976-2985. DOI: 10.1021/Jo00090A014  0.342
1994 Martin DP, Bibart RT, Drueckhammer DG. Synthesis of novel analogs of acetyl coenzyme A: Mimics of enzyme reaction intermediates Journal of the American Chemical Society. 116: 4660-4668. DOI: 10.1021/ja00090a014  0.317
1991 Drueckhammer DG, Hennen WJ, Pederson RL, Barbas CF, Gautheron CM, Krach T, Wong CH. Enzyme catalysis in synthetic carbohydrate chemistry Synthesis. 499-525. DOI: 10.1055/S-1991-26506  0.527
1990 WONG C, DRUECKHAMMER DG, DURRWACHTER JR, LACHER B, CHAUVET CJ, WANG Y, SWEERS HM, SMITH GL, YANG LJ, HENNEN WJ. ChemInform Abstract: Enzyme-Catalyzed Synthesis of Carbohydrates Cheminform. 21. DOI: 10.1002/chin.199033344  0.462
1989 Drueckhammer DG, Durrwachter JR, Pederson RL, Crans DC, Daniels L, Wong CH. Reversible and in situ formation of organic arsenates and vanadates as organic phosphate mimics in enzymatic reactions: Mechanistic investigation of aldol reactions and synthetic applications Journal of Organic Chemistry. 54: 70-77. DOI: 10.1021/Jo00262A021  0.421
1987 Drueckhammer DG, Sadozai SK, Wong CH, Roberts SM. Biphasic one-pot synthesis of two useful and separable compounds using nicotinamide cofactor-requiring enzymes: Syntheses of (S)-4-hydroxyhexanoate and its lactone Enzyme and Microbial Technology. 9: 564-570. DOI: 10.1016/0141-0229(87)90089-5  0.422
1986 Durrwachter JR, Drueckhammer DG, Nozaki K, Sweers HM, Wong CH. Enzymic aldol condensation/isomerization as a route to unusual sugar derivatives. Journal of the American Chemical Society. 108: 7812-8. PMID 22283291 DOI: 10.1021/Ja00284A053  0.44
1985 Wong CH, Drueckhammer DG. Enzymatic synthesis of chiral hydroxy compounds using immobilized glucose dehydrogenase from Bacillus cereus for NAD(P)H regeneration Bio/Technology. 3: 649-651. DOI: 10.1038/Nbt0785-649  0.433
1985 Drueckhammer DG, Wong CH. Chemoenzymatic syntheses of fluoro sugar phosphates and analogues Journal of Organic Chemistry. 50: 5912-5913. DOI: 10.1021/Jo00350A109  0.363
1985 Drueckhammer DG, Riddle VW, Wong CH. FMN reductase catalyzed regeneration of NAD(P) for use in enzymatic synthesis Journal of Organic Chemistry. 50: 5387-5389. DOI: 10.1021/Jo00225A080  0.337
1985 Wong C, Drueckhammer DG, Sweers HM. Enzymatic vs. fermentative synthesis: thermostable glucose dehydrogenase catalyzed regeneration of NAD(P)H for use in enzymatic synthesis Journal of the American Chemical Society. 107: 4028-4031. DOI: 10.1021/Ja00299A044  0.389
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