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Chi-Huey Wong - Publications

Affiliations: 
1983-1989 Texas A & M University, College Station, TX, United States 
 1989- Scripps Research Institute 
Area:
organic chemistry
Website:
http://www.scripps.edu/chem/wong/boss.htm
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Year Citation  Score
2023 Chou O, Juang YP, Chao TL, Tsai SF, Chiu PF, Chiou CT, Tsai KC, Chang SY, Liang PH, Wong CH. Isolation of Anti-SARS-CoV-2 Natural Products Extracted from and the Semi-synthesis of Antiviral Derivatives. Journal of Natural Products. PMID 37267066 DOI: 10.1021/acs.jnatprod.3c00104  0.628
2022 Uchimura K, Nishitsuji K, Chiu LT, Ohgita T, Saito H, Allain F, Gannedi V, Wong CH, Hung SC. Design and Synthesis of 6-O-Phosphorylated Heparan Sulfate Oligosaccharides to Inhibit Amyloid β Aggregation. Chembiochem : a European Journal of Chemical Biology. e202200191. PMID 35585797 DOI: 10.1002/cbic.202200191  0.752
2021 Gannedi V, Villuri BK, Reddy SN, Ku CC, Wong CH, Hung SC. Practical Remdesivir Synthesis through One-Pot Organocatalyzed Asymmetric ()-P-Phosphoramidation. The Journal of Organic Chemistry. PMID 33634692 DOI: 10.1021/acs.joc.0c02888  0.779
2021 Jan JT, Cheng TR, Juang YP, Ma HH, Wu YT, Yang WB, Cheng CW, Chen X, Chou TH, Shie JJ, Cheng WC, Chein RJ, Mao SS, Liang PH, Ma C, ... ... Wong CH, et al. Identification of existing pharmaceuticals and herbal medicines as inhibitors of SARS-CoV-2 infection. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33452205 DOI: 10.1073/pnas.2021579118  0.785
2020 Pawar S, Hsu L, Narendar Reddy T, Ravinder M, Ren CT, Lin YW, Cheng YY, Lin TW, Hsu TL, Wang SK, Wong CH, Wu CY. Synthesis of Asymmetric N-Glycans as Common Core Substrates for Structural Diversification through Selective Enzymatic Glycosylation. Acs Chemical Biology. PMID 32830946 DOI: 10.1021/Acschembio.0C00359  0.729
2020 Dey S, Lo HJ, Wong CH. Programmable One-Pot Synthesis of Heparin Pentasaccharide Fondaparinux. Organic Letters. PMID 32496799 DOI: 10.1021/Acs.Orglett.0C01386  0.715
2020 Chiu LT, Sabbavarapu NM, Lin WC, Fan CY, Wu CC, Cheng TR, Wong CH, Hung SC. A Trisaccharide Sulfate and its Sulfonamide as Effective Substrate and Inhibitor of Human Endo-O-sulfatase-1. Journal of the American Chemical Society. PMID 32083852 DOI: 10.1021/Jacs.0C00005  0.724
2019 Cheng CW, Zhou Y, Pan WH, Dey S, Wu CY, Hsu WL, Wong CH. Hierarchical and Programmable One-Pot Oligosaccharide Synthesis. Journal of Visualized Experiments : Jove. PMID 31545316 DOI: 10.3791/59987  0.733
2019 Cheng CW, Wu CY, Hsu WL, Wong CH. Programmable One-pot Synthesis of Oligosaccharides. Biochemistry. PMID 31454239 DOI: 10.1021/Acs.Biochem.9B00613  0.33
2019 Dey S, Lo HJ, Wong CH. An Efficient Modular One-Pot Synthesis of Heparin-Based Anticoagulant Idraparinux. Journal of the American Chemical Society. PMID 31244187 DOI: 10.1021/Jacs.9B03266  0.74
2019 Lo HJ, Krasnova L, Dey S, Cheng T, Liu H, Tsai TI, Wu KB, Wu CY, Wong CH. Synthesis of Sialidase-Resistant Oligosaccharide and Antibody Glycoform Containing α2,6-Linked 3F-Neu5Ac. Journal of the American Chemical Society. PMID 30969765 DOI: 10.1021/Jacs.9B01991  0.778
2019 Krasnova L, Wong CH. Oligosaccharide Synthesis and Translational Innovation. Journal of the American Chemical Society. PMID 30716271 DOI: 10.1021/Jacs.8B11005  0.336
2018 Dey S, Bajaj SO, Tsai TI, Lo HJ, Wu K, Wong CH. Synthesis of Modular Building Blocks using Glycosyl Phosphate Donors for the Construction of Asymmetric N-Glycans. Tetrahedron. 74: 6003-6011. PMID 30983640 DOI: 10.1016/J.Tet.2018.08.039  0.745
2018 Cheng CW, Zhou Y, Pan WH, Dey S, Wu CY, Hsu WL, Wong CH. Hierarchical and programmable one-pot synthesis of oligosaccharides. Nature Communications. 9: 5202. PMID 30523255 DOI: 10.1038/S41467-018-07618-8  0.736
2018 Dey S, Wong CH. Programmable one-pot synthesis of heparin pentasaccharides enabling access to regiodefined sulfate derivatives. Chemical Science. 9: 6685-6691. PMID 30310602 DOI: 10.1039/C8Sc01743C  0.74
2018 Wang X, Krasnova L, Wu KB, Wu WS, Cheng TJ, Wong CH. Towards new antibiotics targeting bacterial transglycosylase: Synthesis of a Lipid II analog as stable transition-state mimic inhibitor. Bioorganic & Medicinal Chemistry Letters. PMID 29602680 DOI: 10.1016/J.Bmcl.2018.03.035  0.348
2018 Shivatare VS, Shivatare SS, Lee CD, Liang CH, Liao KS, Cheng YY, Saidachary G, Wu CY, Lin NH, Kwong PD, Burton DR, Wu CY, Wong CH. Unprecedented Role of Hybrid N-Glycans as Ligands for HIV-1 Broadly Neutralizing Antibodies. Journal of the American Chemical Society. PMID 29578688 DOI: 10.1021/Jacs.8B00896  0.3
2018 Shivatare SS, Shivatare VS, Wu CY, Wong CH. Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling. Journal of Visualized Experiments : Jove. PMID 29443078 DOI: 10.3791/55855  0.318
2017 Huang LY, Wang SC, Cheng TR, Wong CH. The undecaprenyl phosphate phosphatase activity of undecaprenol kinase regulates the lipid pool in Gram positive bacteria. Biochemistry. PMID 28872301 DOI: 10.1021/Acs.Biochem.7B00603  0.304
2017 Ting C, Lin Y, Wu C, Wong C. Design of Disaccharide Modules for a Programmable One‐Pot Synthesis of Building Blocks with LacNAc Repeating Units for Asymmetric N‐Glycans Asian Journal of Organic Chemistry. 6: 1800-1807. DOI: 10.1002/Ajoc.201700393  0.355
2016 Krasnova L, Wong CH. Exploring human glycosylation for better therapies. Molecular Aspects of Medicine. PMID 27178988 DOI: 10.1016/J.Mam.2016.05.003  0.326
2016 Krasnova L, Wong CH. Understanding the Chemistry and Biology of Glycosylation with Glycan Synthesis. Annual Review of Biochemistry. PMID 27145845 DOI: 10.1146/Annurev-Biochem-060614-034420  0.346
2016 Shivatare SS, Chang SH, Tsai TI, Tseng SY, Shivatare VS, Lin YS, Cheng YY, Ren CT, Lee CC, Pawar S, Tsai CS, Shih HW, Zeng YF, Liang CH, Kwong PD, ... ... Wong CH, et al. Modular synthesis of N-glycans and arrays for the hetero-ligand binding analysis of HIV antibodies. Nature Chemistry. 8: 338-46. PMID 27001729 DOI: 10.1038/Nchem.2463  0.308
2015 Li X, Kawamura A, Andrews CD, Miller JL, Wu D, Tsao T, Zhang M, Oren D, Padte NN, Porcelli SA, Wong CH, Kappe SH, Ho DD, Tsuji M. Colocalization of a CD1d-Binding Glycolipid with a Radiation-Attenuated Sporozoite Vaccine in Lymph Node-Resident Dendritic Cells for a Robust Adjuvant Effect. Journal of Immunology (Baltimore, Md. : 1950). 195: 2710-21. PMID 26254338 DOI: 10.4049/Jimmunol.1403017  0.527
2015 Wong MC, Yang YZ, Lam CS, Choi WH, Dai NY, Wu Y, Wong CK, Sin SW, Chio UF, U SP, Martins RP. Self-Reconfiguration Property of a Mixed Signal Controller for Improving Power Quality Compensation During Light Loading Ieee Transactions On Power Electronics. 30: 5938-5951. DOI: 10.1109/TPEL.2014.2376983  0.349
2014 Hsu CH, Schelwies M, Enck S, Huang LY, Huang SH, Chang YF, Cheng TJ, Cheng WC, Wong CH. Iminosugar C-glycoside analogues of α-D-GlcNAc-1-phosphate: synthesis and bacterial transglycosylase inhibition. The Journal of Organic Chemistry. 79: 8629-37. PMID 25137529 DOI: 10.1021/Jo501340S  0.325
2013 Padte NN, Boente-Carrera M, Andrews CD, McManus J, Grasperge BF, Gettie A, Coelho-dos-Reis JG, Li X, Wu D, Bruder JT, Sedegah M, Patterson N, Richie TL, Wong CH, Ho DD, et al. A glycolipid adjuvant, 7DW8-5, enhances CD8+ T cell responses induced by an adenovirus-vectored malaria vaccine in non-human primates. Plos One. 8: e78407. PMID 24205224 DOI: 10.1371/Journal.Pone.0078407  0.573
2013 Huang SH, Wu WS, Huang LY, Huang WF, Fu WC, Chen PT, Fang JM, Cheng WC, Cheng TJ, Wong CH. New continuous fluorometric assay for bacterial transglycosylase using Förster resonance energy transfer. Journal of the American Chemical Society. 135: 17078-89. PMID 24131464 DOI: 10.1021/Ja407985M  0.319
2013 Tsai TI, Lee HY, Chang SH, Wang CH, Tu YC, Lin YC, Hwang DR, Wu CY, Wong CH. Effective sugar nucleotide regeneration for the large-scale enzymatic synthesis of Globo H and SSEA4. Journal of the American Chemical Society. 135: 14831-9. PMID 24044869 DOI: 10.1021/Ja4075584  0.335
2013 Shivatare SS, Chang SH, Tsai TI, Ren CT, Chuang HY, Hsu L, Lin CW, Li ST, Wu CY, Wong CH. Efficient convergent synthesis of bi-, tri-, and tetra-antennary complex type N-glycans and their HIV-1 antigenicity. Journal of the American Chemical Society. 135: 15382-91. PMID 24032650 DOI: 10.1021/Ja409097C  0.315
2013 Liao SF, Liang CH, Ho MY, Hsu TL, Tsai TI, Hsieh YS, Tsai CM, Li ST, Cheng YY, Tsao SM, Lin TY, Lin ZY, Yang WB, Ren CT, Lin KI, ... ... Wong CH, et al. Immunization of fucose-containing polysaccharides from Reishi mushroom induces antibodies to tumor-associated Globo H-series epitopes. Proceedings of the National Academy of Sciences of the United States of America. 110: 13809-14. PMID 23908400 DOI: 10.1073/pnas.1312457110  0.638
2013 Yang CY, Chen JB, Tsai TF, Tsai YC, Tsai CY, Liang PH, Hsu TL, Wu CY, Netea MG, Wong CH, Hsieh SL. CLEC4F is an inducible C-type lectin in F4/80-positive cells and is involved in alpha-galactosylceramide presentation in liver. Plos One. 8: e65070. PMID 23762286 DOI: 10.1371/Journal.Pone.0065070  0.641
2013 Ohara K, Lin CC, Yang PJ, Hung WT, Yang WB, Cheng TJ, Fang JM, Wong CH. Synthesis and bioactivity of β-(1→4)-linked oligomannoses and partially acetylated derivatives. The Journal of Organic Chemistry. 78: 6390-411. PMID 23745711 DOI: 10.1021/Jo4005266  0.331
2013 Chen KT, Kuan YC, Fu WC, Liang PH, Cheng TJ, Wong CH, Cheng WC. Rapid preparation of mycobacterium N-glycolyl Lipid I and Lipid II derivatives: a biocatalytic approach. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 834-8. PMID 23229320 DOI: 10.1002/Chem.201203251  0.636
2013 Doores KJ, Huber M, Le KM, Wang SK, Doyle-Cooper C, Cooper A, Pantophlet R, Wong CH, Nemazee D, Burton DR. 2G12-expressing B cell lines may aid in HIV carbohydrate vaccine design strategies. Journal of Virology. 87: 2234-41. PMID 23221565 DOI: 10.1128/Jvi.02820-12  0.707
2013 Al-Shareffi E, Chaubard JL, Leonhard-Melief C, Wang SK, Wong CH, Haltiwanger RS. 6-alkynyl fucose is a bioorthogonal analog for O-fucosylation of epidermal growth factor-like repeats and thrombospondin type-1 repeats by protein O-fucosyltransferases 1 and 2. Glycobiology. 23: 188-98. PMID 23045360 DOI: 10.1093/Glycob/Cws140  0.707
2012 Hsieh MH, Hung JT, Liw YW, Lu YJ, Wong CH, Yu AL, Liang PH. Synthesis and evaluation of acyl-chain- and galactose-6''-modified analogues of α-GalCer for NKT cell activation. Chembiochem : a European Journal of Chemical Biology. 13: 1689-97. PMID 22730199 DOI: 10.1002/Cbic.201200004  0.668
2012 Zulueta MM, Lin SY, Lin YT, Huang CJ, Wang CC, Ku CC, Shi Z, Chyan CL, Irene D, Lim LH, Tsai TI, Hu YP, Arco SD, Wong CH, Hung SC. α-Glycosylation by D-glucosamine-derived donors: synthesis of heparosan and heparin analogues that interact with mycobacterial heparin-binding hemagglutinin. Journal of the American Chemical Society. 134: 8988-95. PMID 22587381 DOI: 10.1021/Ja302640P  0.733
2012 Hsu Y, Lu XA, Zulueta MM, Tsai CM, Lin KI, Hung SC, Wong CH. Acyl and silyl group effects in reactivity-based one-pot glycosylation: synthesis of embryonic stem cell surface carbohydrates Lc4 and IV(2)Fuc-Lc4. Journal of the American Chemical Society. 134: 4549-52. PMID 22390569 DOI: 10.1021/Ja300284X  0.717
2011 Hsu CH, Hung SC, Wu CY, Wong CH. Toward automated oligosaccharide synthesis. Angewandte Chemie (International Ed. in English). 50: 11872-923. PMID 22127846 DOI: 10.1002/Anie.201100125  0.729
2011 Pejchal R, Doores KJ, Walker LM, Khayat R, Huang PS, Wang SK, Stanfield RL, Julien JP, Ramos A, Crispin M, Depetris R, Katpally U, Marozsan A, Cupo A, Maloveste S, ... ... Wong CH, et al. A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield. Science (New York, N.Y.). 334: 1097-103. PMID 21998254 DOI: 10.1126/Science.1213256  0.693
2011 Chu KC, Ren CT, Lu CP, Hsu CH, Sun TH, Han JL, Pal B, Chao TA, Lin YF, Wu SH, Wong CH, Wu CY. Efficient and stereoselective synthesis of α(2→9) oligosialic acids: from monomers to dodecamers. Angewandte Chemie (International Ed. in English). 50: 9391-5. PMID 21948436 DOI: 10.1002/Anie.201101794  0.307
2011 Meng FC, Chen KT, Huang LY, Shih HW, Chang HH, Nien FY, Liang PH, Cheng TJ, Wong CH, Cheng WC. Total synthesis of polyprenyl N-glycolyl lipid II as a mycobacterial transglycosylase substrate. Organic Letters. 13: 5306-9. PMID 21913698 DOI: 10.1021/Ol2021687  0.671
2011 Walker LM, Huber M, Doores KJ, Falkowska E, Pejchal R, Julien JP, Wang SK, Ramos A, Chan-Hui PY, Moyle M, Mitcham JL, Hammond PW, Olsen OA, Phung P, Fling S, ... Wong CH, et al. Broad neutralization coverage of HIV by multiple highly potent antibodies. Nature. 477: 466-70. PMID 21849977 DOI: 10.1038/Nature10373  0.706
2011 Schmaltz RM, Hanson SR, Wong CH. Enzymes in the synthesis of glycoconjugates. Chemical Reviews. 111: 4259-307. PMID 21749134 DOI: 10.1021/Cr200113W  0.312
2011 Wu CY, Wong CH. Chemistry and glycobiology. Chemical Communications (Cambridge, England). 47: 6201-7. PMID 21503322 DOI: 10.1039/C0Cc04359A  0.346
2011 Chang CF, Pan JF, Lin CN, Wu IL, Wong CH, Lin CH. Rapid characterization of sugar-binding specificity by in-solution proximity binding with photosensitizers. Glycobiology. 21: 895-902. PMID 21325337 DOI: 10.1093/Glycob/Cwr021  0.302
2011 Liang CH, Wang SK, Lin CW, Wang CC, Wong CH, Wu CY. Effects of neighboring glycans on antibody-carbohydrate interaction. Angewandte Chemie (International Ed. in English). 50: 1608-12. PMID 21308915 DOI: 10.1002/Anie.201003482  0.726
2011 Wu CY, Wong CH. Programmable one-pot glycosylation. Topics in Current Chemistry. 301: 223-52. PMID 21290217 DOI: 10.1007/128_2010_109  0.329
2011 Tsai BL, Han JL, Ren CT, Wu CY, Wong CH. Programmable one-pot synthesis of tumor-associated carbohydrate antigens Lewis X dimer and KH-1 epitopes Tetrahedron Letters. 52: 2132-2135. DOI: 10.1016/J.Tetlet.2010.11.055  0.32
2011 Hsu C, Hung S, Wu C, Wong C. Auf dem Weg zur automatisierten Oligosaccharid- Synthese Angewandte Chemie. 123: 12076-12129. DOI: 10.1002/Ange.201100125  0.702
2010 Li X, Fujio M, Imamura M, Wu D, Vasan S, Wong CH, Ho DD, Tsuji M. Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant. Proceedings of the National Academy of Sciences of the United States of America. 107: 13010-5. PMID 20616071 DOI: 10.1073/Pnas.1006662107  0.593
2010 Shih HW, Chen KT, Chen SK, Huang CY, Cheng TJ, Ma C, Wong CH, Cheng WC. Combinatorial approach toward synthesis of small molecule libraries as bacterial transglycosylase inhibitors. Organic & Biomolecular Chemistry. 8: 2586-93. PMID 20485795 DOI: 10.1039/C000622J  0.342
2010 Astronomo RD, Kaltgrad E, Udit AK, Wang SK, Doores KJ, Huang CY, Pantophlet R, Paulson JC, Wong CH, Finn MG, Burton DR. Defining criteria for oligomannose immunogens for HIV using icosahedral virus capsid scaffolds. Chemistry & Biology. 17: 357-70. PMID 20416507 DOI: 10.1016/J.Chembiol.2010.03.012  0.772
2010 Hsu CH, Chu KC, Lin YS, Han JL, Peng YS, Ren CT, Wu CY, Wong CH. Highly alpha-selective sialyl phosphate donors for efficient preparation of natural sialosides. Chemistry (Weinheim An Der Bergstrasse, Germany). 16: 1754-60. PMID 20066711 DOI: 10.1002/Chem.200903035  0.327
2010 Payne RJ, Wong CH. Advances in chemical ligation strategies for the synthesis of glycopeptides and glycoproteins. Chemical Communications (Cambridge, England). 46: 21-43. PMID 20024291 DOI: 10.1039/B913845E  0.504
2010 Sugiyama M, Hong Z, Greenberg WA, Wong CH. Recent Advances in Aldolase-Catalyzed Synthesis of Unnatural Sugars and Iminocyclitols Biocatalysis and Biomolecular Engineering. 405-419. DOI: 10.5059/Yukigoseikyokaishi.66.605  0.341
2009 Lewis JC, Bastian S, Bennett CS, Fu Y, Mitsuda Y, Chen MM, Greenberg WA, Wong CH, Arnold FH. Chemoenzymatic elaboration of monosaccharides using engineered cytochrome P450BM3 demethylases. Proceedings of the National Academy of Sciences of the United States of America. 106: 16550-5. PMID 19805336 DOI: 10.1073/Pnas.0908954106  0.657
2009 Schiefner A, Fujio M, Wu D, Wong CH, Wilson IA. Structural evaluation of potent NKT cell agonists: implications for design of novel stimulatory ligands. Journal of Molecular Biology. 394: 71-82. PMID 19732779 DOI: 10.1016/J.Jmb.2009.08.061  0.592
2009 Xu R, Hanson SR, Zhang Z, Yang YY, Schultz PG, Wong CH. Site-specific incorporation of the mucin-type N-acetylgalactosamine-alpha-O-threonine into protein in Escherichia coli. Journal of the American Chemical Society. 131: 13883. PMID 19731911 DOI: 10.1021/Ja906705A  0.31
2009 Motiei L, Rahimipour S, Thayer DA, Wong CH, Ghadiri MR. Antibacterial cyclic D,L-alpha-glycopeptides. Chemical Communications (Cambridge, England). 3693-5. PMID 19557251 DOI: 10.1039/B902455G  0.731
2009 Hong Z, Liu L, Sugiyama M, Fu Y, Wong CH. Concise synthesis of iminocyclitols via Petasis-type aminocyclization. Journal of the American Chemical Society. 131: 8352-3. PMID 19530721 DOI: 10.1021/Ja901656E  0.312
2009 Wu CY, Liang PH, Wong CH. New development of glycan arrays. Organic & Biomolecular Chemistry. 7: 2247-54. PMID 19462030 DOI: 10.1039/B902510N  0.644
2008 Liang PH, Imamura M, Li X, Wu D, Fujio M, Guy RT, Wu BC, Tsuji M, Wong CH. Quantitative microarray analysis of intact glycolipid-CD1d interaction and correlation with cell-based cytokine production. Journal of the American Chemical Society. 130: 12348-54. PMID 18712867 DOI: 10.1021/ja8012787  0.722
2008 Bennett CS, Dean SM, Payne RJ, Ficht S, Brik A, Wong CH. Sugar-assisted glycopeptide ligation with complex oligosaccharides: scope and limitations. Journal of the American Chemical Society. 130: 11945-52. PMID 18698778 DOI: 10.1021/Ja8010513  0.688
2008 Kinjo Y, Pei B, Bufali S, Raju R, Richardson SK, Imamura M, Fujio M, Wu D, Khurana A, Kawahara K, Wong CH, Howell AR, Seeberger PH, Kronenberg M. Natural Sphingomonas glycolipids vary greatly in their ability to activate natural killer T cells. Chemistry & Biology. 15: 654-64. PMID 18635002 DOI: 10.1016/J.Chembiol.2008.05.012  0.6
2008 Shie JJ, Fang JM, Wong CH. A concise and flexible synthesis of the potent anti-influenza agents tamiflu and tamiphosphor Angewandte Chemie - International Edition. 47: 5788-5791. PMID 18613158 DOI: 10.1002/Anie.200801959  0.314
2008 Hsieh YS, Chien C, Liao SK, Liao SF, Hung WT, Yang WB, Lin CC, Cheng TJ, Chang CC, Fang JM, Wong CH. Structure and bioactivity of the polysaccharides in medicinal plant Dendrobium huoshanense. Bioorganic & Medicinal Chemistry. 16: 6054-68. PMID 18467102 DOI: 10.1016/j.bmc.2008.04.042  0.621
2008 Payne RJ, Ficht S, Greenberg WA, Wong CH. Cysteine-free peptide and glycopeptide ligation by direct aminolysis. Angewandte Chemie (International Ed. in English). 47: 4411-5. PMID 18442150 DOI: 10.1002/Anie.200705298  0.42
2008 Astronomo RD, Lee HK, Scanlan CN, Pantophlet R, Huang CY, Wilson IA, Blixt O, Dwek RA, Wong CH, Burton DR. A glycoconjugate antigen based on the recognition motif of a broadly neutralizing human immunodeficiency virus antibody, 2G12, is immunogenic but elicits antibodies unable to bind to the self glycans of gp120. Journal of Virology. 82: 6359-68. PMID 18434393 DOI: 10.1128/Jvi.00293-08  0.75
2008 Wang SK, Liang PH, Astronomo RD, Hsu TL, Hsieh SL, Burton DR, Wong CH. Targeting the carbohydrates on HIV-1: Interaction of oligomannose dendrons with human monoclonal antibody 2G12 and DC-SIGN. Proceedings of the National Academy of Sciences of the United States of America. 105: 3690-5. PMID 18310320 DOI: 10.1073/Pnas.0712326105  0.782
2008 Ficht S, Payne RJ, Guy RT, Wong CH. Solid-phase synthesis of peptide and glycopeptide thioesters through side-chain-anchoring strategies. Chemistry (Weinheim An Der Bergstrasse, Germany). 14: 3620-9. PMID 18278777 DOI: 10.1002/Chem.200701978  0.485
2008 Liang PH, Wu CY, Greenberg WA, Wong CH. Glycan arrays: biological and medical applications. Current Opinion in Chemical Biology. 12: 86-92. PMID 18258211 DOI: 10.1016/J.Cbpa.2008.01.031  0.652
2008 Cheng TJ, Sung MT, Liao HY, Chang YF, Chen CW, Huang CY, Chou LY, Wu YD, Chen YH, Cheng YS, Wong CH, Ma C, Cheng WC. Domain requirement of moenomycin binding to bifunctional transglycosylases and development of high-throughput discovery of antibiotics. Proceedings of the National Academy of Sciences of the United States of America. 105: 431-6. PMID 18182485 DOI: 10.1073/Pnas.0710868105  0.305
2008 Wu D, Fujio M, Wong CH. Glycolipids as immunostimulating agents. Bioorganic & Medicinal Chemistry. 16: 1073-83. PMID 18006319 DOI: 10.1016/J.Bmc.2007.10.026  0.586
2008 Koeller KM, Wong CH. Recycling of sugar nucleotides in enzymatic g1ycosylation Carbohydrates in Chemistry and Biology. 2: 663-684. DOI: 10.1002/9783527618255.ch26  0.712
2007 Sugiyama M, Hong Z, Liang PH, Dean SM, Whalen LJ, Greenberg WA, Wong CH. D-Fructose-6-phosphate aldolase-catalyzed one-pot synthesis of iminocyclitols. Journal of the American Chemical Society. 129: 14811-7. PMID 17985886 DOI: 10.1021/Ja073911I  0.687
2007 Payne RJ, Ficht S, Tang S, Brik A, Yang YY, Case DA, Wong CH. Extended sugar-assisted glycopeptide ligations: development, scope, and applications. Journal of the American Chemical Society. 129: 13527-36. PMID 17935327 DOI: 10.1021/Ja073653P  0.511
2007 Polat T, Wong CH. Anomeric reactivity-based one-pot synthesis of heparin-like oligosaccharides. Journal of the American Chemical Society. 129: 12795-800. PMID 17914818 DOI: 10.1021/Ja073098R  0.355
2007 Casey CP, Wong CH. Partly cloudy with a chance of showers. Acs Chemical Biology. 2: 573-6. PMID 17894433 DOI: 10.1021/Cb7001895  0.433
2007 Shie JJ, Fang JM, Wang SY, Tsai KC, Cheng YS, Yang AS, Hsiao SC, Su CY, Wong CH. Synthesis of tamiflu and its phosphonate congeners possessing potent anti-influenza activity. Journal of the American Chemical Society. 129: 11892-3. PMID 17850083 DOI: 10.1021/Ja073992I  0.305
2007 Shao YM, Yang WB, Peng HP, Hsu MF, Tsai KC, Kuo TH, Wang AH, Liang PH, Lin CH, Yang AS, Wong CH. Structure-based design and synthesis of highly potent SARS-CoV 3CL protease inhibitors. Chembiochem : a European Journal of Chemical Biology. 8: 1654-7. PMID 17722121 DOI: 10.1002/Cbic.200700254  0.347
2007 Liang PH, Wang SK, Wong CH. Quantitative analysis of carbohydrate-protein interactions using glycan microarrays: determination of surface and solution dissociation constants. Journal of the American Chemical Society. 129: 11177-84. PMID 17705486 DOI: 10.1021/ja072931h  0.777
2007 Kaltgrad E, Sen Gupta S, Punna S, Huang CY, Chang A, Wong CH, Finn MG, Blixt O. Anti-carbohydrate antibodies elicited by polyvalent display on a viral scaffold. Chembiochem : a European Journal of Chemical Biology. 8: 1455-62. PMID 17676704 DOI: 10.1002/Cbic.200700225  0.748
2007 Bennett CS, Wong CH. Chemoenzymatic approaches to glycoprotein synthesis. Chemical Society Reviews. 36: 1227-38. PMID 17619683 DOI: 10.1039/B617709C  0.648
2007 Ficht S, Payne RJ, Brik A, Wong CH. Second-generation sugar-assisted ligation: a method for the synthesis of cysteine-containing glycopeptides. Angewandte Chemie (International Ed. in English). 46: 5975-9. PMID 17607677 DOI: 10.1002/Anie.200700546  0.494
2007 Chang YJ, Huang JR, Tsai YC, Hung JT, Wu D, Fujio M, Wong CH, Yu AL. Potent immune-modulating and anticancer effects of NKT cell stimulatory glycolipids. Proceedings of the National Academy of Sciences of the United States of America. 104: 10299-304. PMID 17566107 DOI: 10.1073/Pnas.0703824104  0.575
2007 Yang YY, Ficht S, Brik A, Wong CH. Sugar-assisted ligation in glycoprotein synthesis Journal of the American Chemical Society. 129: 7690-7701. PMID 17523644 DOI: 10.1021/Ja0708971  0.362
2007 Brik A, Wong CH. Sugar-assisted ligation for the synthesis of glycopeptides Chemistry - a European Journal. 13: 5670-5675. PMID 17508364 DOI: 10.1002/Chem.200700330  0.337
2007 Hsu TL, Hanson SR, Kishikawa K, Wang SK, Sawa M, Wong CH. Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells. Proceedings of the National Academy of Sciences of the United States of America. 104: 2614-9. PMID 17296930 DOI: 10.1073/pnas.0611307104  0.703
2007 Hong Z, Liu L, Hsu CC, Wong CH. Three-step synthesis of sialic acids and derivatives. Angewandte Chemie (International Ed. in English). 45: 7417-21. PMID 17031889 DOI: 10.1002/Anie.200601555  0.31
2007 Hanson SR, Greenberg WA, Wong CH. Probing glycans with the copper(I)-catalyzed [3 + 2] azide - Alkyne cycloaddition Qsar and Combinatorial Science. 26: 1243-1252. DOI: 10.1002/Qsar.200740112  0.33
2007 Ficht S, Payne R, Brik A, Wong C. Zuckervermittelte Peptidverknüpfung der zweiten Generation: eine Methode zur Synthese von cysteinhaltigen Glycopeptiden Angewandte Chemie. 119: 6079-6083. DOI: 10.1002/Ange.200700546  0.437
2007 Dean SM, Greenberg WA, Wong CH. Recent advances in aldolase-catalyzed asymmetric synthesis Advanced Synthesis and Catalysis. 349: 1308-1320. DOI: 10.1002/Adsc.200700115  0.318
2006 Thayer DA, Wong CH. Vancomycin analogues containing monosaccharides exhibit improved antibiotic activity: a combined one-pot enzymatic glycosylation and chemical diversification strategy. Chemistry, An Asian Journal. 1: 445-52. PMID 17441081 DOI: 10.1002/Asia.200600084  0.752
2006 Lee JC, Greenberg WA, Wong CH. Programmable reactivity-based one-pot oligosaccharide synthesis. Nature Protocols. 1: 3143-52. PMID 17406577 DOI: 10.1038/Nprot.2006.489  0.355
2006 Brik A, Ficht S, Yang YY, Bennett CS, Wong CH. Sugar-assisted ligation of N-linked glycopeptides with broad sequence tolerance at the ligation junction. Journal of the American Chemical Society. 128: 15026-33. PMID 17105315 DOI: 10.1021/Ja065601Q  0.656
2006 Brik A, Ficht S, Wong CH. Strategies for the preparation of homogenous glycoproteins Current Opinion in Chemical Biology. 10: 638-644. PMID 17046315 DOI: 10.1016/J.Cbpa.2006.10.003  0.306
2006 Hanson SR, Whalen LJ, Wong CH. Synthesis and evaluation of general mechanism-based inhibitors of sulfatases based on (difluoro)methyl phenyl sulfate and cyclic phenyl sulfamate motifs. Bioorganic & Medicinal Chemistry. 14: 8386-95. PMID 17045481 DOI: 10.1016/J.Bmc.2006.09.002  0.328
2006 Kinjo Y, Tupin E, Wu D, Fujio M, Garcia-Navarro R, Benhnia MR, Zajonc DM, Ben-Menachem G, Ainge GD, Painter GF, Khurana A, Hoebe K, Behar SM, Beutler B, Wilson IA, ... ... Wong CH, et al. Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria. Nature Immunology. 7: 978-86. PMID 16921381 DOI: 10.1038/Ni1380  0.54
2006 Liang FS, Greenberg WA, Hammond JA, Hoffmann J, Head SR, Wong CH. Evaluation of RNA-binding specificity of aminoglycosides with DNA microarrays. Proceedings of the National Academy of Sciences of the United States of America. 103: 12311-6. PMID 16891415 DOI: 10.1073/Pnas.0605264103  0.54
2006 Liu H, Wong CH. Characterization of a transglycosylase domain of Streptococcus pneumoniae PBP1b. Bioorganic & Medicinal Chemistry. 14: 7187-95. PMID 16870450 DOI: 10.1016/J.Bmc.2006.06.058  0.744
2006 Fujio M, Wu D, Garcia-Navarro R, Ho DD, Tsuji M, Wong CH. Structure-based discovery of glycolipids for CD1d-mediated NKT cell activation: tuning the adjuvant versus immunosuppression activity. Journal of the American Chemical Society. 128: 9022-3. PMID 16834361 DOI: 10.1021/Ja062740Z  0.578
2006 Sanna MG, Wang SK, Gonzalez-Cabrera PJ, Don A, Marsolais D, Matheu MP, Wei SH, Parker I, Jo E, Cheng WC, Cahalan MD, Wong CH, Rosen H. Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo. Nature Chemical Biology. 2: 434-41. PMID 16829954 DOI: 10.1038/Nchembio804  0.693
2006 Huang K, Wu B, Lin C, Luo S, Chen C, Wong C, Lin C. Multi-enzyme one-pot strategy for the synthesis of sialyl Lewis X-containing PSGL-1 glycopeptide Carbohydrate Research. 341: 2151-2155. PMID 16762328 DOI: 10.1016/J.Carres.2006.04.047  0.346
2006 Brik A, Yang YY, Ficht S, Wong CH. Sugar-assisted glycopeptide ligation. Journal of the American Chemical Society. 128: 5626-7. PMID 16637616 DOI: 10.1021/Ja061165W  0.362
2006 Brik A, Wu CY, Wong CH. Microtiter plate based chemistry and in situ screening: A useful approach for rapid inhibitor discovery Organic and Biomolecular Chemistry. 4: 1446-1457. PMID 16604207 DOI: 10.1039/B600055J  0.334
2006 Wu D, Zajonc DM, Fujio M, Sullivan BA, Kinjo Y, Kronenberg M, Wilson IA, Wong CH. Design of natural killer T cell activators: structure and function of a microbial glycosphingolipid bound to mouse CD1d. Proceedings of the National Academy of Sciences of the United States of America. 103: 3972-7. PMID 16537470 DOI: 10.1073/Pnas.0600285103  0.597
2006 Brigl M, van den Elzen P, Chen X, Meyers JH, Wu D, Wong CH, Reddington F, Illarianov PA, Besra GS, Brenner MB, Gumperz JE. Conserved and heterogeneous lipid antigen specificities of CD1d-restricted NKT cell receptors. Journal of Immunology (Baltimore, Md. : 1950). 176: 3625-34. PMID 16517731 DOI: 10.4049/Jimmunol.176.6.3625  0.575
2006 Liang PH, Cheng WC, Lee YL, Yu HP, Wu YT, Lin YL, Wong CH. Novel five-membered iminocyclitol derivatives as selective and potent glycosidase inhibitors: new structures for antivirals and osteoarthritis. Chembiochem : a European Journal of Chemical Biology. 7: 165-73. PMID 16397876 DOI: 10.1002/cbic.200500321  0.625
2006 Huang CY, Thayer DA, Chang AY, Best MD, Hoffmann J, Head S, Wong CH. Carbohydrate microarray for profiling the antibodies interacting with Globo H tumor antigen. Proceedings of the National Academy of Sciences of the United States of America. 103: 15-20. PMID 16373501 DOI: 10.1073/Pnas.0509693102  0.779
2006 Liu L, Bennett CS, Wong CH. Advances in glycoprotein synthesis. Chemical Communications (Cambridge, England). 21-33. PMID 16353085 DOI: 10.1039/B513165K  0.649
2006 Liang FS, Brik A, Lin YC, Elder JH, Wong CH. Epoxide opening in water and screening in situ for rapid discovery of enzyme inhibitors in microtiter plates. Bioorganic & Medicinal Chemistry. 14: 1058-62. PMID 16275107 DOI: 10.1016/J.Bmc.2005.09.026  0.566
2006 Sugiyama M, Hong Z, Whalen LJ, Greenberg WA, Wong CH. Borate as a phosphate ester mimic in aldolase-catalyzed reactions: Practical synthesis of L-fructose and L-iminocyclitols Advanced Synthesis and Catalysis. 348: 2555-2559. DOI: 10.1002/Adsc.200600356  0.319
2005 Zajonc DM, Maricic I, Wu D, Halder R, Roy K, Wong CH, Kumar V, Wilson IA. Structural basis for CD1d presentation of a sulfatide derived from myelin and its implications for autoimmunity. The Journal of Experimental Medicine. 202: 1517-26. PMID 16314439 DOI: 10.1084/Jem.20051625  0.584
2005 Wei SH, Rosen H, Matheu MP, Sanna MG, Wang SK, Jo E, Wong CH, Parker I, Cahalan MD. Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses. Nature Immunology. 6: 1228-35. PMID 16273098 DOI: 10.1038/Ni1269  0.69
2005 Wu CY, Brik A, Wang SK, Chen YH, Wong CH. Tetrabutylammonium fluoride-mediated rapid alkylation reaction in microtiter plates for the discovery of enzyme inhibitors in situ Chembiochem. 6: 2176-2180. PMID 16270365 DOI: 10.1002/Cbic.200500295  0.735
2005 Calarese DA, Lee HK, Huang CY, Best MD, Astronomo RD, Stanfield RL, Katinger H, Burton DR, Wong CH, Wilson IA. Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12. Proceedings of the National Academy of Sciences of the United States of America. 102: 13372-7. PMID 16174734 DOI: 10.1073/Pnas.0505763102  0.775
2005 Thayer DA, Yu HN, Galan MC, Wong CH. A general strategy toward S-linked glycopeptides. Angewandte Chemie (International Ed. in English). 44: 4596-9. PMID 15991213 DOI: 10.1002/Anie.200500090  0.76
2005 Shie JJ, Fang JM, Kuo CJ, Kuo TH, Liang PH, Huang HJ, Yang WB, Lin CH, Chen JL, Wu YT, Wong CH. Discovery of potent anilide inhibitors against the severe acute respiratory syndrome 3CL protease. Journal of Medicinal Chemistry. 48: 4469-73. PMID 15974598 DOI: 10.1021/Jm050184Y  0.301
2005 Brik A, Wu CY, Best MD, Wong CH. Tetrabutylammonium fluoride-assisted rapid N9-alkylation on purine ring: Application to combinatorial reactions in microtiter plates for the discovery of potent sulfotransferase inhibitors in situ Bioorganic and Medicinal Chemistry. 13: 4622-4626. PMID 15953729 DOI: 10.1016/J.Bmc.2005.02.066  0.673
2005 Brik A, Alexandratos J, Lin YC, Elder JH, Olson AJ, Wlodawer A, Goodsell DS, Wong CH. 1,2,3-triazole as a peptide surrogate in the rapid synthesis of HIV-1 protease inhibitors. Chembiochem : a European Journal of Chemical Biology. 6: 1167-9. PMID 15934050 DOI: 10.1002/Cbic.200500101  0.312
2005 Kinjo Y, Wu D, Kim G, Xing GW, Poles MA, Ho DD, Tsuji M, Kawahara K, Wong CH, Kronenberg M. Recognition of bacterial glycosphingolipids by natural killer T cells. Nature. 434: 520-5. PMID 15791257 DOI: 10.1038/Nature03407  0.577
2005 Xing GW, Wu D, Poles MA, Horowitz A, Tsuji M, Ho DD, Wong CH. Synthesis and human NKT cell stimulating properties of 3-O-sulfo-alpha/beta-galactosylceramides. Bioorganic & Medicinal Chemistry. 13: 2907-16. PMID 15781400 DOI: 10.1016/J.Bmc.2005.02.018  0.59
2005 Wu D, Xing GW, Poles MA, Horowitz A, Kinjo Y, Sullivan B, Bodmer-Narkevitch V, Plettenburg O, Kronenberg M, Tsuji M, Ho DD, Wong CH. Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 1351-6. PMID 15665086 DOI: 10.1073/Pnas.0408696102  0.731
2005 Fridman M, Belakhov V, Lee LV, Liang FS, Wong CH, Baasov T. Dual effect of synthetic aminoglycosides: antibacterial activity against Bacillus anthracis and inhibition of anthrax lethal factor. Angewandte Chemie (International Ed. in English). 44: 447-52. PMID 15624157 DOI: 10.1002/Anie.200462003  0.538
2004 Lin H, Thayer DA, Wong CH, Walsh CT. Macrolactamization of glycosylated peptide thioesters by the thioesterase domain of tyrocidine synthetase. Chemistry & Biology. 11: 1635-42. PMID 15610847 DOI: 10.1016/J.Chembiol.2004.09.015  0.768
2004 Liang FS, Wang SK, Nakatani T, Wong CH. Targeting RNAs with tobramycin analogues. Angewandte Chemie (International Ed. in English). 43: 6496-500. PMID 15578772 DOI: 10.1002/Anie.200460558  0.744
2004 Nyffeler PT, Durón SG, Burkart MD, Vincent SP, Wong CH. Selectfluor: mechanistic insight and applications. Angewandte Chemie (International Ed. in English). 44: 192-212. PMID 15578736 DOI: 10.1002/Anie.200400648  0.781
2004 Blixt O, Head S, Mondala T, Scanlan C, Huflejt ME, Alvarez R, Bryan MC, Fazio F, Calarese D, Stevens J, Razi N, Stevens DJ, Skehel JJ, van Die I, Burton DR, ... ... Wong CH, et al. Printed covalent glycan array for ligand profiling of diverse glycan binding proteins. Proceedings of the National Academy of Sciences of the United States of America. 101: 17033-8. PMID 15563589 DOI: 10.1073/Pnas.0407902101  0.701
2004 Hanson S, Best M, Bryan MC, Wong CH. Chemoenzymatic synthesis of oligosaccharides and glycoproteins. Trends in Biochemical Sciences. 29: 656-63. PMID 15544952 DOI: 10.1016/J.Tibs.2004.10.004  0.791
2004 Hanson SR, Best MD, Wong CH. Sulfatases: structure, mechanism, biological activity, inhibition, and synthetic utility. Angewandte Chemie (International Ed. in English). 43: 5736-63. PMID 15493058 DOI: 10.1002/anie.200300632  0.611
2004 Heine A, Luz JG, Wong CH, Wilson IA. Analysis of the class I aldolase binding site architecture based on the crystal structure of 2-deoxyribose-5-phosphate aldolase at 0.99A resolution. Journal of Molecular Biology. 343: 1019-34. PMID 15476818 DOI: 10.1016/J.Jmb.2004.08.066  0.311
2004 Liu J, Numa MM, Liu H, Huang SJ, Sears P, Shikhman AR, Wong CH. Synthesis and high-throughput screening of N-acetyl-beta-hexosaminidase inhibitor libraries targeting osteoarthritis. The Journal of Organic Chemistry. 69: 6273-83. PMID 15357586 DOI: 10.1021/Jo049355H  0.758
2004 Nyffeler PT, Boyle NA, Eltepu L, Wong CH, Eschenmoser A, Lerner RA, Wentworth P. Dihydrogen trioxide (HOOOH) is generated during the thermal reaction between hydrogen peroxide and ozone. Angewandte Chemie (International Ed. in English). 43: 4656-9. PMID 15317003 DOI: 10.1002/Anie.200460457  0.752
2004 Chapman E, Best MD, Hanson SR, Wong CH. Sulfotransferases: structure, mechanism, biological activity, inhibition, and synthetic utility. Angewandte Chemie (International Ed. in English). 43: 3526-48. PMID 15293241 DOI: 10.1002/Anie.200300631  0.697
2004 Bryan MC, Fazio F, Lee HK, Huang CY, Chang A, Best MD, Calarese DA, Blixt O, Paulson JC, Burton D, Wilson IA, Wong CH. Covalent display of oligosaccharide arrays in microtiter plates. Journal of the American Chemical Society. 126: 8640-1. PMID 15250702 DOI: 10.1021/Ja048433F  0.773
2004 Wu CY, Jan JT, Ma SH, Kuo CJ, Juan HF, Cheng YS, Hsu HH, Huang HC, Wu D, Brik A, Liang FS, Liu RS, Fang JM, Chen ST, Liang PH, ... Wong CH, et al. Small molecules targeting severe acute respiratory syndrome human coronavirus. Proceedings of the National Academy of Sciences of the United States of America. 101: 10012-7. PMID 15226499 DOI: 10.1073/Pnas.0403596101  0.691
2004 Best MD, Brik A, Chapman E, Lee LV, Cheng WC, Wong CH. Rapid discovery of potent sulfotransferase inhibitors by diversity-oriented reaction in microplates followed by in situ screening. Chembiochem : a European Journal of Chemical Biology. 5: 811-9. PMID 15174164 DOI: 10.1002/Cbic.200300841  0.706
2004 Bryan MC, Lee LV, Wong CH. High-throughput identification of fucosyltransferase inhibitors using carbohydrate microarrays. Bioorganic & Medicinal Chemistry Letters. 14: 3185-8. PMID 15149672 DOI: 10.1016/J.Bmcl.2004.04.001  0.701
2004 Lee LV, Bower KE, Liang FS, Shi J, Wu D, Sucheck SJ, Vogt PK, Wong CH. Inhibition of the proteolytic activity of anthrax lethal factor by aminoglycosides. Journal of the American Chemical Society. 126: 4774-5. PMID 15080670 DOI: 10.1021/Ja0495359  0.784
2004 Agnelli F, Sucheck SJ, Marby KA, Rabuka D, Yao SL, Sears PS, Liang FS, Wong CH. Dimeric aminoglycosides as antibiotics. Angewandte Chemie (International Ed. in English). 43: 1562-6. PMID 15022234 DOI: 10.1002/Anie.200353225  0.688
2004 Yu HN, Furukawa J, Ikeda T, Wong CH. Novel efficient routes to heparin monosaccharides and disaccharides achieved via regio- and stereoselective glycosidation. Organic Letters. 6: 723-6. PMID 14986959 DOI: 10.1021/Ol036390M  0.348
2004 Heck MP, Vincent SP, Murray BW, Bellamy F, Wong CH, Mioskowski C. Cyclic amidine sugars as transition-state analogue inhibitors of glycosidases: potent competitive inhibitors of mannosidases. Journal of the American Chemical Society. 126: 1971-9. PMID 14971930 DOI: 10.1021/Ja037822R  0.307
2004 Lee HK, Scanlan CN, Huang CY, Chang AY, Calarese DA, Dwek RA, Rudd PM, Burton DR, Wilson IA, Wong CH. Reactivity-based one-pot synthesis of oligomannoses: defining antigens recognized by 2G12, a broadly neutralizing anti-HIV-1 antibody. Angewandte Chemie (International Ed. in English). 43: 1000-3. PMID 14966891 DOI: 10.1002/Anie.200353105  0.742
2004 Chou CH, Wu CS, Chen CH, Lu LD, Kulkarni SS, Wong CH, Hung SC. Regioselective glycosylation of neamine core: a facile entry to kanamycin B related analogues. Organic Letters. 6: 585-8. PMID 14961629 DOI: 10.1021/Ol0363927  0.789
2004 Zhang Z, Gildersleeve J, Yang YY, Xu R, Loo JA, Uryu S, Wong CH, Schultz PG. A new strategy for the synthesis of glycoproteins. Science (New York, N.Y.). 303: 371-3. PMID 14726590 DOI: 10.1126/Science.1089509  0.309
2004 Bryan MC, Wong CH. Aminoglycoside array for the high-throughput analysis of small molecule-RNA interactions Tetrahedron Letters. 45: 3639-3642. DOI: 10.1016/J.Tetlet.2004.03.035  0.691
2004 Fazio F, Bryan MC, Lee HK, Chang A, Wong CH. Assembly of sugars on polystyrene plates: A new facile microarray fabrication technique Tetrahedron Letters. 45: 2689-2692. DOI: 10.1016/J.Tetlet.2004.01.159  0.696
2004 Liu J, Hsu C, Wong C. Sequential aldol condensation catalyzed by DERA mutant Ser238Asp and a formal total synthesis of atorvastatin Tetrahedron Letters. 45: 2439-2441. DOI: 10.1016/J.Tetlet.2004.01.110  0.319
2004 Nyffeler PT, Durón SG, Burkart MD, Vincent SP, Wong C. Selectfluor: Mechanismen und Anwendungen Angewandte Chemie. 117: 196-217. DOI: 10.1002/Ange.200400648  0.756
2004 Chapman E, Best MD, Hanson SR, Wong C. Sulfotransferasen: Struktur, Mechanismus, biologische Aktivität, Inhibierung, Anwendung in Synthesen Angewandte Chemie. 116: 3610-3632. DOI: 10.1002/Ange.200300631  0.472
2003 Brik A, Muldoon J, Lin YC, Elder JH, Goodsell DS, Olson AJ, Fokin VV, Sharpless KB, Wong CH. Rapid diversity-oriented synthesis in microtiter plates for in situ screening of HIV protease inhibitors. Chembiochem : a European Journal of Chemical Biology. 4: 1246-8. PMID 14613121 DOI: 10.1002/Cbic.200300724  0.338
2003 Ritter TK, Mong KK, Liu H, Nakatani T, Wong CH. A programmable one-pot oligosaccharide synthesis for diversifying the sugar domains of natural products: a case study of vancomycin. Angewandte Chemie (International Ed. in English). 42: 4657-60. PMID 14533156 DOI: 10.1002/Anie.200351534  0.774
2003 Wong CH, Liang FS. Surface plasmon resonance study of RNA-aminoglycoside interactions. Methods in Enzymology. 362: 340-53. PMID 12968375 DOI: 10.1016/S0076-6879(03)01024-3  0.542
2003 Wong CH, Bryan MC. Sugar arrays in microtiter plates. Methods in Enzymology. 362: 218-25. PMID 12968366 DOI: 10.1016/S0076-6879(03)01015-2  0.698
2003 Mong TKK, Lee LV, Brown JR, Esko JD, Wong CH. Synthesis of N-acetyllactosamine derivatives with variation in the aglycon moiety for the study of inhibition of sialyl Lewis x expression Chembiochem. 4: 835-840. PMID 12964157 DOI: 10.1002/Cbic.200300650  0.309
2003 Franke D, Machajewski T, Hsu C, Wong C. One-Pot Synthesis of l-Fructose Using Coupled Multienzyme Systems Based on Rhamnulose-1-phosphate Aldolase Journal of Organic Chemistry. 68: 6828-6831. PMID 12919060 DOI: 10.1021/Jo030021M  0.768
2003 Lee LV, Mitchell ML, Huang SJ, Fokin VV, Sharpless KB, Wong CH. A potent and highly selective inhibitor of human alpha-1,3-fucosyltransferase via click chemistry. Journal of the American Chemical Society. 125: 9588-9. PMID 12904015 DOI: 10.1021/Ja0302836  0.331
2003 Liu H, Ritter TK, Sadamoto R, Sears PS, Wu M, Wong CH. Acceptor specificity and inhibition of the bacterial cell-wall glycosyltransferase MurG. Chembiochem : a European Journal of Chemical Biology. 4: 603-9. PMID 12851929 DOI: 10.1002/Cbic.200300557  0.792
2003 Wada M, Hsu CC, Franke D, Mitchell M, Heine A, Wilson I, Wong CH. Directed evolution of N-acetylneuraminic acid aldolase to catalyze enantiomeric aldol reactions. Bioorganic & Medicinal Chemistry. 11: 2091-8. PMID 12670660 DOI: 10.1016/S0968-0896(03)00052-X  0.304
2003 Mong TK, Huang CY, Wong CH. A new reactivity-based one-pot synthesis of N-acetyllactosamine oligomers. The Journal of Organic Chemistry. 68: 2135-42. PMID 12636372 DOI: 10.1021/Jo0206420  0.765
2003 Liu H, Wang L, Brock A, Wong CH, Schultz PG. A method for the generation of glycoprotein mimetics. Journal of the American Chemical Society. 125: 1702-3. PMID 12580587 DOI: 10.1021/Ja029433N  0.762
2003 Mong TK, Lee HK, Duron SG, Wong CH. Reactivity-based one-pot total synthesis of fucose GM1 oligosaccharide: a sialylated antigenic epitope of small-cell lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 100: 797-802. PMID 12552090 DOI: 10.1073/Pnas.0337590100  0.351
2003 Chapman E, Bryan MC, Wong CH. Mechanistic studies of beta-arylsulfotransferase IV. Proceedings of the National Academy of Sciences of the United States of America. 100: 910-5. PMID 12547913 DOI: 10.1073/Pnas.0337638100  0.748
2003 DeSantis G, Liu J, Clark DP, Heine A, Wilson IA, Wong CH. Structure-based mutagenesis approaches toward expanding the substrate specificity of D-2-deoxyribose-5-phosphate aldolase. Bioorganic & Medicinal Chemistry. 11: 43-52. PMID 12467706 DOI: 10.1016/S0968-0896(02)00429-7  0.346
2002 Liu J, Wong CH. Aldolase-catalyzed asymmetric synthesis of novel pyranose synthons as a new entry to heterocycles and epothilones. Angewandte Chemie (International Ed. in English). 41: 1404-7. PMID 19750780 DOI: 10.1002/1521-3773(20020415)41:8<1404::Aid-Anie1404>3.0.Co;2-G  0.347
2002 Chapman E, Ding S, Schultz PG, Wong CH. A potent and highly selective sulfotransferase inhibitor. Journal of the American Chemical Society. 124: 14524-5. PMID 12465948 DOI: 10.1021/Ja021086U  0.483
2002 Fazio F, Bryan MC, Blixt O, Paulson JC, Wong CH. Synthesis of sugar arrays in microtiter plate. Journal of the American Chemical Society. 124: 14397-402. PMID 12452714 DOI: 10.1021/Ja020887U  0.714
2002 Nyffeler PT, Liang CH, Koeller KM, Wong CH. The chemistry of amine-azide interconversion: catalytic diazotransfer and regioselective azide reduction. Journal of the American Chemical Society. 124: 10773-8. PMID 12207533 DOI: 10.1021/Ja0264605  0.782
2002 Thunnissen MMGM, Andersson B, Samuelsson B, Wong C, Haeggström JZ. Crystal structures of leukotriene A4 hydrolase in complex with captopril and two competitive tight-binding inhibitors The Faseb Journal. 16: 1648-1650. PMID 12207002 DOI: 10.1096/Fj.01-1017Fje  0.308
2002 Brik A, Lin YC, Elder J, Wong CH. A quick diversity-oriented amide-forming reaction to optimize p-subsite residues of HIV protease inhibitors Chemistry and Biology. 9: 891-896. PMID 12204688 DOI: 10.1016/S1074-5521(02)00184-9  0.358
2002 Sadamoto R, Niikura K, Sears PS, Liu H, Wong CH, Suksomcheep A, Tomita F, Monde K, Nishimura S. Cell-wall engineering of living bacteria. Journal of the American Chemical Society. 124: 9018-9. PMID 12148983 DOI: 10.1021/Ja026133X  0.742
2002 Bryan MC, Plettenburg O, Sears P, Rabuka D, Wacowich-Sgarbi S, Wong CH. Saccharide display on microtiter plates. Chemistry & Biology. 9: 713-20. PMID 12079783 DOI: 10.1016/S1074-5521(02)00155-2  0.792
2002 Plettenburg O, Bodmer-Narkevitch V, Wong CH. Synthesis of alpha-galactosyl ceramide, a potent immunostimulatory agent. The Journal of Organic Chemistry. 67: 4559-64. PMID 12076157 DOI: 10.1021/Jo0201530  0.655
2002 Chapman E, Wong CH. A pH sensitive colorometric assay for the high-throughput screening of enzyme inhibitors and substrates: a case study using kinases. Bioorganic & Medicinal Chemistry. 10: 551-5. PMID 11814841 DOI: 10.1016/S0968-0896(01)00306-6  0.463
2002 Izumi M, Shen GJ, Wacowich-Sgarbi S, Nakatani T, Plettenburg O, Wong CH. Microbial glycosyltransferases for carbohydrate synthesis: alpha-2,3-sialyltransferase from Neisseria gonorrheae. Journal of the American Chemical Society. 123: 10909-18. PMID 11686694 DOI: 10.1021/Ja011382R  0.676
2002 Zhang Z, Niikura K, Huang X, Wong C. A strategy for the one-pot synthesis of sialylated oligosaccharides Canadian Journal of Chemistry. 80: 1051-1054. DOI: 10.1139/V02-131  0.365
2002 Liu J, DeSantis G, Wong C. Structure-based rationalization of aldolase-catalyzed asymmetric synthesis Canadian Journal of Chemistry. 80: 643-645. DOI: 10.1139/V02-094  0.353
2002 Liu J, Huang CY, Wong CH. An efficient method for the preparation of 2-hydroxy- and 2-aminoglycals from glycosyl sulfoxides Tetrahedron Letters. 43: 3447-3448. DOI: 10.1016/S0040-4039(02)00555-5  0.751
2002 Zhang Z, Wong C. Regioselective benzoylation of sugars mediated by excessive Bu2SnO: observation of temperature promoted migration Tetrahedron. 58: 6513-6519. DOI: 10.1016/S0040-4020(02)00661-0  0.327
2002 Plettenburg O, Mui C, Bodmer-Narkevitch V, Wong C. Rapid Preparation of Glycolipid Libraries by Cross Metathesis Advanced Synthesis & Catalysis. 344: 622. DOI: 10.1002/1615-4169(200208)344:6/7<622::Aid-Adsc622>3.0.Co;2-W  0.658
2001 Saotome C, Wong C, Kanie O. Combinatorial library of five-membered iminocyclitol and the inhibitory activities against glyco-enzymes Chemistry & Biology. 8: 1061-1070. PMID 11731297 DOI: 10.1016/S1074-5521(01)00074-6  0.355
2001 Ritter TK, Wong CH. Carbohydrate-Based Antibiotics: A New Approach to Tackling the Problem of Resistance. Angewandte Chemie (International Ed. in English). 40: 3508-3533. PMID 11592183 DOI: 10.1002/1521-3773(20011001)40:19<3508::Aid-Anie3508>3.0.Co;2-I  0.596
2001 Liu H, Sadamoto R, Sears PS, Wong CH. An efficient chemoenzymatic strategy for the synthesis of wild-type and vancomycin-resistant bacterial cell-wall precursors: UDP-N-acetylmuramyl-peptides. Journal of the American Chemical Society. 123: 9916-7. PMID 11583564 DOI: 10.1021/Ja011708W  0.746
2001 Silvestri MG, Wong CH. Opening of thiiranes: Preparation of orthogonal protected 2-thioglyceraldehyde Journal of Organic Chemistry. 66: 910-914. PMID 11430112 DOI: 10.1021/Jo001392V  0.301
2001 Le VD, Mak CC, Lin YC, Elder JH, Wong CH. Structure - Activity studies of FIV and HIV protease inhibitors containing allophenylnorstatine Bioorganic and Medicinal Chemistry. 9: 1185-1195. PMID 11377177 DOI: 10.1016/S0968-0896(00)00346-1  0.301
2001 Sears P, Wong CH. Toward automated synthesis of oligosaccharides and glycoproteins. Science (New York, N.Y.). 291: 2344-50. PMID 11269314 DOI: 10.1126/Science.1058899  0.341
2001 Koeller KM, Wong CH. Enzymes for chemical synthesis. Nature. 409: 232-40. PMID 11196651 DOI: 10.1038/35051706  0.755
2001 Romero A, Wong CH. Chemo-enzymatic total synthesis of 3-epiaustraline, australine, and 7-epialexine. The Journal of Organic Chemistry. 65: 8264-8. PMID 11101383 DOI: 10.1021/Jo000933D  0.355
2001 Izumi M, Wong C. Microbial Sialyltransferases for Carbohydrate Synthesis Trends in Glycoscience and Glycotechnology. 13: 345-360. DOI: 10.4052/Tigg.13.345  0.329
2001 Ye X, Huang X, Wong C. Conversion of the carboxy group of sialic acid donors to a protectedhydroxymethyl group yields an efficient reagent for the synthesis of the unnaturalbeta-linkage Chemical Communications. 974-975. DOI: 10.1039/B102166B  0.311
2001 Ritter TK, Wong CH. Synthesis of N-acetylglucosamine thiazoline/lipid II hybrids Tetrahedron Letters. 42: 615-618. DOI: 10.1016/S0040-4039(00)02020-7  0.611
2001 Mitchell M, Qaio L, Wong C. Chemical‐Enzymatic Synthesis of Iminocyclitol Phosphonic Acids Advanced Synthesis & Catalysis. 343: 596-599. DOI: 10.1002/1615-4169(200108)343:6/7<596::Aid-Adsc596>3.0.Co;2-V  0.334
2001 Ritter TK, Wong C. Kohlenhydrate in der Antibiotikaforschung: ein neuer Ansatz zur Resistenzbekämpfung Angewandte Chemie. 113: 3616-3641. DOI: 10.1002/1521-3757(20011001)113:19<3616::Aid-Ange3616>3.0.Co;2-B  0.577
2000 Koeller KM, Wong CH. Synthesis of complex carbohydrates and glycoconjugates: enzyme-based and programmable one-pot strategies. Chemical Reviews. 100: 4465-94. PMID 11749355 DOI: 10.1021/Cr990297N  0.754
2000 Sucheck SJ, Wong CH. RNA as a target for small molecules Current Opinion in Chemical Biology. 4: 678-686. PMID 11102874 DOI: 10.1016/S1367-5931(00)00142-3  0.627
2000 Fong S, Machajewski TD, Mak CC, Wong C. Directed evolution of D-2-keto-3-deoxy-6-phosphogluconate aldolase to new variants for the efficient synthesis of D- and L-sugars. Chemistry & Biology. 7: 873-883. PMID 11094340 DOI: 10.1016/S1074-5521(00)00035-1  0.777
2000 Koeller KM, Wong CH. Complex carbohydrate synthesis tools for glycobiologists: enzyme-based approach and programmable one-pot strategies. Glycobiology. 10: 1157-69. PMID 11087708 DOI: 10.1093/Glycob/10.11.1157  0.753
2000 Burkart MD, Vincent SP, Düffels A, Murray BW, Ley SV, Wong CH. Chemo-enzymatic synthesis of fluorinated sugar nucleotide: useful mechanistic probes for glycosyltransferases. Bioorganic & Medicinal Chemistry. 8: 1937-46. PMID 11003139 DOI: 10.1016/S0968-0896(00)00139-5  0.568
2000 Burkart MD, Izumi M, Chapman E, Lin CH, Wong CH. Regeneration of PAPS for the enzymatic synthesis of sulfated oligosaccharides. The Journal of Organic Chemistry. 65: 5565-74. PMID 10970295 DOI: 10.1021/Jo000266O  0.641
2000 Koeller KM, Wong CH. Emerging themes in medicinal glycoscience. Nature Biotechnology. 18: 835-41. PMID 10932151 DOI: 10.1038/78435  0.748
2000 Koeller KM, Smith ME, Wong CH. Chemoenzymatic synthesis of PSGL-1 glycopeptides: sulfation on tyrosine affects glycosyltransferase-catalyzed synthesis of the O-glycan. Bioorganic & Medicinal Chemistry. 8: 1017-25. PMID 10882013 DOI: 10.1016/S0968-0896(00)00041-9  0.764
2000 Takayanagi M, Flessner T, Wong C. A strategy for the solution-phase parallel synthesis of N-(pyrrolidinylmethyl)hydroxamic acids. Journal of Organic Chemistry. 65: 3811-3815. PMID 10864769 DOI: 10.1021/Jo000186K  0.332
2000 Ye XS, Wong CH. Anomeric reactivity-based one-pot oligosaccharide synthesis: A rapid route to oligosaccharide libraries Journal of Organic Chemistry. 65: 2410-2431. PMID 10789453 DOI: 10.1021/Jo991558W  0.339
2000 Le V, Wong C. Synthesis of 2-substituted polyhydroxytetrahydropyrimidines (N-hydroxy cyclic guanidino-sugars): transition-state mimics of enzymatic glycosidic cleavage. Journal of Organic Chemistry. 65: 2399-2409. PMID 10789452 DOI: 10.1021/Jo9915574  0.344
2000 Shibata K, Hiruma K, Kanie O, Wong C. Synthesis of 1,1-linked galactosyl mannosides carrying a thiazine ring as mimetics of sialyl Lewis X antigen: investigation of the effect of carboxyl group orientation on P-selectin inhibition. Journal of Organic Chemistry. 65: 2393-2398. PMID 10789451 DOI: 10.1021/Jo991556B  0.308
2000 Koeller KM, Wong CH. Chemoenzymatic synthesis of sialyl-trimeric-Lewis x. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 1243-51. PMID 10785811 DOI: 10.1002/(Sici)1521-3765(20000403)6:7<1243::Aid-Chem1243>3.0.Co;2-J  0.765
2000 Machajewski TD, Wong C. The Catalytic Asymmetric Aldol Reaction. Angewandte Chemie. 39: 1352-1375. PMID 10777624 DOI: 10.1002/(Sici)1521-3773(20000417)39:8<1352::Aid-Anie1352>3.0.Co;2-J  0.772
2000 Sucheck SJ, Greenberg WA, Tolbert TJ, Wong C. Design of Small Molecules That Recognize RNA: Development of Aminoglycosides as Potential Antitumor Agents That Target Oncogenic RNA Sequences Angewandte Chemie. 39: 1080-1084. PMID 10760928 DOI: 10.1002/(Sici)1521-3773(20000317)39:6<1080::Aid-Anie1080>3.0.Co;2-B  0.611
2000 Wittmann V, Datta AK, Koeller KM, Wong CH. Chemoenzymatic synthesis and fluorescent visualization of cell-surface selectin-bound sialyl Lewis x derivatives. Chemistry (Weinheim An Der Bergstrasse, Germany). 6: 162-71. PMID 10747401 DOI: 10.1002/(Sici)1521-3765(20000103)6:1<162::Aid-Chem162>3.0.Co;2-9  0.735
2000 Koeller KM, Smith MEB, Wong CH. Tyrosine sulfation on a PSGL-1 glycopeptide influences the reactivity of glycosyltransferases responsible for synthesis of the attached O-glycan [16] Journal of the American Chemical Society. 122: 742-743. DOI: 10.1021/Ja993820O  0.741
2000 Sucheck SJ, Wong AL, Koeller KM, Boehr DD, Draker KA, Sears P, Wright GD, Wong CH. Design of bifunctional antibiotics that target bacterial rRNA and inhibit resistance-causing enzymes [11] Journal of the American Chemical Society. 122: 5230-5231. DOI: 10.1021/Ja000575W  0.769
2000 Koeller KM, Smith MEB, Huang RF, Wong CH. Chemoenzymatic synthesis of a PSGL-1 N-terminal glycopeptide containing tyrosine sulfate and α-O-linked sialyl Lewis X [15] Journal of the American Chemical Society. 122: 4241-4242. DOI: 10.1021/Ja0004938  0.743
2000 Tolbert TJ, Wong CH. Intein-mediated synthesis of proteins containing carbohydrates and other molecular probes Journal of the American Chemical Society. 122. DOI: 10.1021/Ja0000192  0.304
2000 Flessner T, Wong C. Efficient synthesis of triazoles from d-arabinose and l-fucose Tetrahedron Letters. 41: 7805-7808. DOI: 10.1016/S0040-4039(00)01356-3  0.327
2000 Sun X, Kanie Y, Guo C, Kanie O, Suzuki Y, Wong C. Syntheses of C-3-Modified Sialylglycosides as Selective Inhibitors of Influenza Hemagglutinin and Neuraminidase European Journal of Organic Chemistry. 2000: 2643-2653. DOI: 10.1002/1099-0690(200007)2000:14<2643::Aid-Ejoc2643>3.0.Co;2-1  0.32
2000 Machajewski TD, Wong C. Die katalysierte asymmetrische Aldolreaktion Angewandte Chemie. 112: 1406-1430. DOI: 10.1002/(Sici)1521-3757(20000417)112:8<1406::Aid-Ange1406>3.0.Co;2-R  0.739
1999 Vincent SP, Burkart MD, Tsai CY, Zhang Z, Wong CH. Electrophilic Fluorination-Nucleophilic Addition Reaction Mediated by Selectfluor: Mechanistic Studies and New Applications. The Journal of Organic Chemistry. 64: 5264-5279. PMID 34237857 DOI: 10.1021/jo990686h  0.51
1999 Shen GJ, Datta AK, Izumi M, Koeller KM, Wong CH. Expression of alpha2,8/2,9-polysialyltransferase from Escherichia coli K92. Characterization of the enzyme and its reaction products. The Journal of Biological Chemistry. 274: 35139-46. PMID 10574996 DOI: 10.1074/Jbc.274.49.35139  0.747
1999 Burkart MD, Wong CH. A continuous assay for the spectrophotometric analysis of sulfotransferases using aryl sulfotransferase IV. Analytical Biochemistry. 274: 131-7. PMID 10527506 DOI: 10.1006/Abio.1999.4264  0.557
1999 Burkart MD, Izumi M, Wong CH. Enzymatic Regeneration of 3'-Phosphoadenosine-5'-Phosphosulfate Using Aryl Sulfotransferase for the Preparative Enzymatic Synthesis of Sulfated Carbohydrates. Angewandte Chemie (International Ed. in English). 38: 2747-2750. PMID 10508369 DOI: 10.1002/(Sici)1521-3773(19990917)38:18<2747::Aid-Anie2747>3.0.Co;2-2  0.569
1999 Huwe CM, Woltering TJ, Jiricek J, Weitz-Schmidt G, Wong C. Design, synthesis and biological evaluation of aryl-substituted sialyl Lewis X mimetics prepared via cross-metathesis of C-fucopeptides. Bioorganic & Medicinal Chemistry. 7: 773-788. PMID 10400330 DOI: 10.1016/S0968-0896(98)00245-4  0.335
1999 Lin C, Morı́s-Varas F, Weitz-Schmidt G, Wong C. Synthesis of sialyl Lewis x mimetics as selectin inhibitors by enzymatic aldol condensation reactions. Bioorganic & Medicinal Chemistry. 7: 425-433. PMID 10220028 DOI: 10.1016/S0968-0896(98)00242-9  0.351
1999 Sears P, Witte K, Wong C. Synthesis of glycopeptides and glycoproteins Collection of Czechoslovak Chemical Communications. 1: 211-216. DOI: 10.1135/Css199901211  0.341
1999 Machajewski TD, Wong C. Chemoenzymatic Synthesis of Key Epothilone Fragments Synthesis. 1999: 1469-1472. DOI: 10.1055/S-1999-3650  0.77
1999 Burkart MD, Vincent SP, Wong C. An efficient synthesis of CMP-3-fluoroneuraminic acid Chemical Communications. 1525-1526. DOI: 10.1039/A903362I  0.521
1999 Vincent SP, Burkart MD, Tsai CY, Zhang Z, Wong CH. Electrophilic fluorination - Nucleophilic addition reaction mediated by selectfluor: Mechanistic studies and new applications Journal of Organic Chemistry. 64: 5264-5279. DOI: 10.1021/Jo990686H  0.545
1999 Wu WG, Pasternack L, Huang DH, Koeller KM, Lin CC, Seitz O, Wong CH. Structural study on O-glycopeptides: Glycosylation-induced conformational changes of O-GlcNAc, O-LacNAc, O-Sialyl-LacNAc, and O-Sialyl- Lewis-X peptides of the mucin domain of MAdCAM-1 Journal of the American Chemical Society. 121: 2409-2417. DOI: 10.1021/Ja983474V  0.734
1999 Hiranuma S, Kanie O, Wong C. Formation of the 1,2,6-orthoester of mannose and its utilization in the glycosylation reaction Tetrahedron Letters. 40: 6423-6426. DOI: 10.1016/S0040-4039(99)01193-4  0.313
1999 Koeller KM, Wong C. Synthesis of Biologically Active Glycopeptides Journal of the Chinese Chemical Society. 46: 659-685. DOI: 10.1002/Jccs.199900093  0.76
1999 Wong C. Design and Synthesis of Carbohydrate Mimetics: A New Strategy for Tackling the Problem of Carbohydrate-Mediated Biological Recognition Journal of the Chinese Chemical Society. 46: 271-281. DOI: 10.1002/Jccs.199900043  0.338
1999 Depré D, Düffels A, Green LG, Lenz R, Ley SV, Wong C. Synthesis of Glycans from the Glycodelins: Two Undeca-, Two Deca-, Three Nona-, an Octa- and a Heptasaccharide Chemistry - a European Journal. 5: 3326-3340. DOI: 10.1002/(Sici)1521-3765(19991105)5:11<3326::Aid-Chem3326>3.0.Co;2-Q  0.308
1999 Burkart MD, Izumi M, Wong C. Enzymatische Regeneration von 3′-Phosphoadenosin-5′-phosphosulfat mit Aryl-Sulfotransferase zur präparativen enzymatischen Synthese von sulfatierten Kohlenhydraten Angewandte Chemie. 111: 2912-2915. DOI: 10.1002/(Sici)1521-3757(19990917)111:18<2912::Aid-Ange2912>3.0.Co;2-X  0.504
1998 Simanek EE, McGarvey GJ, Jablonowski JA, Wong CH. Selectinminus signCarbohydrate Interactions: From Natural Ligands to Designed Mimics. Chemical Reviews. 98: 833-862. PMID 11848916 DOI: 10.1021/Cr940226I  0.699
1998 Guo CT, Wong CH, Kajimoto T, Miura T, Ida Y, Juneja LR, Kim MJ, Masuda H, Suzuki T, Suzuki Y. Synthetic sialylphosphatidylethanolamine derivatives bind to human influenza A viruses and inhibit viral infection. Glycoconjugate Journal. 15: 1099-108. PMID 10386895 DOI: 10.1023/A:1006961912465  0.564
1998 Tsai C, Park WKC, Weitz-Schmidt G, Ernst B, Wong C. Synthesis of sialyl Lewis X mimetics using the Ugi four-component reaction. Bioorganic & Medicinal Chemistry Letters. 8: 2333-2338. PMID 9873537 DOI: 10.1016/S0960-894X(98)00422-3  0.327
1998 Miura T, Kajimoto T, Jimbo M, Yamagishi K, Inokuchi J, Wong C. Synthesis and evaluation of morpholino- and pyrrolidinosphingolipids as inhibitors of glucosylceramide synthase. Bioorganic & Medicinal Chemistry. 6: 1481-1489. PMID 9801819 DOI: 10.1016/S0968-0896(98)00077-7  0.327
1998 Martin R, Witte KL, Wong C. The synthesis and enzymatic incorporation of sialic acid derivatives for use as tools to study the structure, activity, and inhibition of glycoproteins and other glycoconjugates Bioorganic & Medicinal Chemistry. 6: 1283-1292. PMID 9784869 DOI: 10.1016/S0968-0896(98)00121-7  0.324
1998 Sears P, Wong C. Mechanism-based inhibition of carbohydrate-mediated biological recognitions Chemical Communications. 1161-1170. DOI: 10.1039/A800838H  0.341
1998 Wischnat R, Martin R, Wong C. Synthesis of a New Class of N-Linked Lewis and LacNAc Analogues as Potential Inhibitors of Human Fucosyltransferases: A General Method for the Incorporation of an Iminocyclitol as a Transition-State Mimetic of the Donor Sugar to the Acceptor Journal of Organic Chemistry. 63: 8361-8365. DOI: 10.1021/Jo981245L  0.342
1998 Wittmann V, Takayama S, Gong KW, Weitz-Schmidt G, Wong C. Ligand Recognition by E- and P-Selectin:  Chemoenzymatic Synthesis and Inhibitory Activity of Bivalent Sialyl Lewis x Derivatives and Sialyl Lewis x Carboxylic Acids The Journal of Organic Chemistry. 63: 5137-5143. DOI: 10.1021/Jo980350S  0.569
1998 Simanek EE, Huang D, Pasternack L, Machajewski TD, Seitz O, Millar DS, Dyson HJ, Wong C. Glycosylation of Threonine of the Repeating Unit of RNA Polymerase II with β-LinkedN-Acetylglucosame Leads to a Turnlike Structure Journal of the American Chemical Society. 120: 11567-11575. DOI: 10.1021/Ja982312W  0.777
1998 Witte K, Seitz O, Wong CH. Solution- and solid-phase synthesis of N-protected glycopeptide esters of the benzyl type as substrates for subtilisin-catalyzed glycopeptide couplings Journal of the American Chemical Society. 120: 1979-1989. DOI: 10.1021/Ja9736727  0.342
1998 Alper PB, Hendrix M, Sears P, Wong CH. Probing the specificity of aminoglycoside-ribosomal RNA interactions with designed synthetic analogs Journal of the American Chemical Society. 120: 1965-1978. DOI: 10.1021/Ja972599H  0.304
1998 Hogg JH, Ollmann IR, Wetterholm A, Blomster Andberg M, Haeggström J, Samuelsson B, Wong C. Probing the Activities and Mechanisms of Leukotriene A4 Hydrolase with Synthetic Inhibitors Chemistry - a European Journal. 4: 1698-1713. DOI: 10.1002/(Sici)1521-3765(19980904)4:9<1698::Aid-Chem1698>3.0.Co;2-J  0.333
1997 Koketsu M, Nitoda T, Sugino H, Juneja LR, Kim M, Yamamoto T, Abe N, Kajimoto T, Wong CH. Synthesis of a novel sialic acid derivative (sialylphospholipid) as an antirotaviral agent. Journal of Medicinal Chemistry. 40: 3332-5. PMID 9341907 DOI: 10.1021/Jm9701280  0.321
1997 Wang R, Steensma DH, Takaoka Y, Yun JW, Kajimoto T, Wong CH. A search for pyrophosphate mimics for the development of substrates and inhibitors of glycosyltransferases. Bioorganic & Medicinal Chemistry. 5: 661-72. PMID 9158864 DOI: 10.1016/S0968-0896(97)00005-9  0.306
1997 Hayashi T, Murray BW, Wang R, Wong C. A chemoenzymatic synthesis of UDP-(2-deoxy-2-fluoro)-galactose and evaluation of its interaction with galactosyltransferase. Bioorganic & Medicinal Chemistry. 5: 497-500. PMID 9113327 DOI: 10.1016/S0968-0896(96)00263-5  0.316
1997 Cappi MW, Moree WJ, Qiao L, Marron TG, Weitz-Schmidt G, Wong C. Synthesis of novel 6-amido-6-deoxy-l-galactose derivatives as sialyl Lewis X mimetics. Bioorganic & Medicinal Chemistry. 5: 283-296. PMID 9061193 DOI: 10.1016/S0968-0896(96)00236-2  0.309
1997 Murray BW, Wittmann V, Burkart MD, Hung SC, Wong CH. Mechanism of human alpha-1,3-fucosyltransferase V: glycosidic cleavage occurs prior to nucleophilic attack. Biochemistry. 36: 823-31. PMID 9020780 DOI: 10.1021/Bi962284Z  0.765
1997 Janda KD, Lo LC, Lo CH, Sim MM, Wang R, Wong CH, Lerner RA. Chemical selection for catalysis in combinatorial antibody libraries. Science (New York, N.Y.). 275: 945-8. PMID 9020070 DOI: 10.1126/Science.275.5302.945  0.501
1997 Wittmann V, Wong CH. 1H-tetrazole as catalyst in phosphomorpholidate coupling reactions: Efficient synthesis of GDP-fucose, GDP-mannose, and UDP-galactose Journal of Organic Chemistry. 62: 2144-2147. DOI: 10.1021/Jo9620066  0.33
1997 Burkart MD, Zhang Z, Hung SC, Wong CH. A new method for the synthesis of fluoro-carbohydrates and glycosides using selectfluor Journal of the American Chemical Society. 119: 11743-11746. DOI: 10.1021/Ja9723904  0.788
1997 Kimura T, Vassilev VP, Shen G, Wong C. Enzymatic Synthesis of β-Hydroxy-α-amino Acids Based on Recombinantd- andl-Threonine Aldolases Journal of the American Chemical Society. 119: 11734-11742. DOI: 10.1021/Ja9720422  0.311
1997 Wong C, Moris-Varas F, Hung S, Marron TG, Lin C, Gong KW, Weitz-Schmidt G. Small Molecules as Structural and Functional Mimics of Sialyl Lewis X Tetrasaccharide in Selectin Inhibition: A Remarkable Enhancement of Inhibition by Additional Negative Charge and/or Hydrophobic Group Journal of the American Chemical Society. 119: 8152-8158. DOI: 10.1021/Ja970920Q  0.732
1997 Witte K, Sears P, Martin R, Wong CH. Enzymatic glycoprotein synthesis: Preparation of ribonuclease glycoforms via enzymatic glycopeptide condensation and glycosylation Journal of the American Chemical Society. 119: 2114-2118. DOI: 10.1021/Ja961846Z  0.366
1997 Hung S, Lin C, Wong C. One-pot synthesis of 1-allyl- and 1-allenyl-6-O-acetyl-2,3,4-tri-O-benzyl-α-D-glycosides from methyl tetra-O-benzyl-α-D-glycosides Tetrahedron Letters. 38: 5419-5422. DOI: 10.1016/S0040-4039(97)01204-5  0.715
1997 McGarvey GJ, Wong C. Chemical, Enzymatic and Structural Studies in Molecular Glycobiology Liebigs Annalen. 1997: 1059-1074. DOI: 10.1002/Jlac.199719970604  0.368
1996 Gijsen HJ, Qiao L, Fitz W, Wong CH. Recent Advances in the Chemoenzymatic Synthesis of Carbohydrates and Carbohydrate Mimetics. Chemical Reviews. 96: 443-474. PMID 11848760 DOI: 10.1021/Cr950031Q  0.329
1996 Uchiyama T, Woltering TJ, Wong W, Lin C, Kajimoto T, Takebayashi M, Wéitz-Schmidt G, Asakura T, Noda M, Wong C. Design and synthesis of C-linked fucosides as inhibitors of E-selectin Bioorganic & Medicinal Chemistry. 4: 1149-1165. PMID 8831987 DOI: 10.1016/0968-0896(96)00127-7  0.324
1996 Murray BW, Takayama S, Schultz J, Wong CH. Mechanism and specificity of human alpha-1,3-fucosyltransferase V. Biochemistry. 35: 11183-95. PMID 8780523 DOI: 10.1021/Bi961065A  0.545
1996 Luca CD, Lansing M, Crescenzi F, Martini I, Shen G, O'Regan M, Wong C. Overexpression, one-step purification and characterization of UDP-glucose dehydrogenase and UDP-N-acetylglucosamine pyrophosphorylase Bioorganic & Medicinal Chemistry. 4: 131-141. PMID 8689233 DOI: 10.1016/0968-0896(95)00159-X  0.324
1996 Park WKC, Auer M, Jaksche H, Wong C. Rapid Combinatorial Synthesis of Aminoglycoside Antibiotic Mimetics: Use of a Polyethylene Glycol-Linked Amine and a Neamine-Derived Aldehyde in Multiple Component Condensation as a Strategy for the Discovery of New Inhibitors of the HIV RNA Rev Responsive Element Journal of the American Chemical Society. 118: 10150-10155. DOI: 10.1021/Ja9612817  0.35
1996 Hiruma K, Kajimoto T, Weitz-Schmidt G, Ollmann I, Wong C. Rational Design and Synthesis of a 1,1-Linked Disaccharide That Is 5 Times as Active as Sialyl Lewis X in Binding to E-Selectin Journal of the American Chemical Society. 118: 9265-9270. DOI: 10.1021/Ja9611093  0.307
1996 Morís-Varas F, Qian X, Wong C. Enzymatic/Chemical Synthesis and Biological Evaluation of Seven-Membered Iminocyclitols Journal of the American Chemical Society. 118: 7647-7652. DOI: 10.1021/Ja960975C  0.35
1996 Patterson JE, Ollmann IR, Cravatt BF, Boger DL, Wong CH, Lerner RA. Inhibition of oleamide hydrolase catalyzed hydrolysis of the endogenous sleep-inducing lipid cis-9-octadecenamide Journal of the American Chemical Society. 118: 5938-5945. DOI: 10.1021/Ja954064Z  0.399
1996 Lin C, Shimazaki M, Heck M, Aoki S, Wang R, Kimura T, Ritzèn H, Takayama S, Wu S, Weitz-Schmidt G, Wong C. Synthesis of Sialyl Lewis X Mimetics and Related Structures Using the Glycosyl Phosphite Methodology and Evaluation of E-Selectin Inhibition Journal of the American Chemical Society. 118: 6826-6840. DOI: 10.1021/Ja952265X  0.579
1996 Sears P, Wong CH. Engineering enzymes for bioorganic synthesis: Peptide bond formation Biotechnology Progress. 12: 423-433. DOI: 10.1021/Bp9500730  0.305
1996 Woltering TJ, Weitz-Schmidt G, Wong C. C-Fucopeptides as selectin antagonists: Attachment of lipid moieties enhances the activity Tetrahedron Letters. 37: 9033-9036. DOI: 10.1016/S0040-4039(96)02121-1  0.316
1996 Qian X, Morís-Varas F, Wong C. Synthesis Of C2-Symmetrical Polyhydroxyazepanes As Inhibitors Of Glycosidases Bioorganic & Medicinal Chemistry Letters. 6: 1117-1122. DOI: 10.1016/0960-894X(96)00183-7  0.325
1996 Alper PB, Hung S, Wong C. Metal catalyzed diazo transfer for the synthesis of azides from amines Tetrahedron Letters. 37: 6029-6032. DOI: 10.1016/0040-4039(96)01307-X  0.713
1996 Hung SC, Wong CH. Synthesis of glycosyl chlorides with acid-labile protecting groups Tetrahedron Letters. 37: 4903-4906. DOI: 10.1016/0040-4039(96)01006-4  0.731
1996 Shibata K, Shingu K, Vassiley VP, Nishide K, Fujita T, Node M, Kajimoto T, Wong C. Kinetic and thermodynamic control of L-Threonine aldolase catalyzed reaction and its application to the synthesis of mycestericin D Tetrahedron Letters. 37: 2791-2794. DOI: 10.1016/0040-4039(96)00430-3  0.311
1996 Hung S, Wong C. Samarium Diiodide Mediated Coupling of Glycosyl Phosphates with Carbon Radical or Anion Acceptors—Synthesis of C‐Glycosides Angewandte Chemie. 35: 2671-2674. DOI: 10.1002/Anie.199626711  0.692
1996 Cappi MW, Moree WJ, Qiao L, Marron TG, Weitz‐Schmidt G, Wong C. The Synthesis of Novel 6‐Amido‐6‐Deoxy‐L‐Galactose Derivatives as Potent Sialyl Lewisx Mimetics Angewandte Chemie. 35: 2346-2348. DOI: 10.1002/Anie.199623461  0.345
1996 Wu S, Shimazaki M, Lin C, Qiao L, Moree WJ, Weitz‐Schmidt G, Wong C. Synthesis Of Fucopeptides As Sialyl Lewisx Mimetics Angewandte Chemie. 35: 88-90. DOI: 10.1002/Anie.199600881  0.331
1996 Hung S, Wong C. Samariumdiiodid‐vermittelte Kupplung von Glycosylphosphaten mit Kohlenstoffradikal‐ oder ‐anion‐Acceptoren – Synthese von C‐Glycosiden Angewandte Chemie. 108: 2829-2832. DOI: 10.1002/Ange.19961082225  0.7
1996 Kimura T, Takayama S, Huang H, Wong C. Eine praktikable Synthese von N‐Acetyl‐D‐lactosamin mit Galactose‐Oxidase und β‐Galactosidase Angewandte Chemie. 108: 2503-2505. DOI: 10.1002/Ange.19961082010  0.589
1995 Hogg JH, Ollmann IR, Haeggström JZ, Wetterholm A, Samuelsson B, Wong C. Amino hydroxamic acids as potent inhibitors of leukotriene A4 hydrolase Bioorganic & Medicinal Chemistry. 3: 1405-1415. PMID 8564408 DOI: 10.1016/0968-0896(95)00128-4  0.315
1995 Ollmann IR, Hogg JH, Muñoz B, Haeggström JZ, Samuelsson B, Wong C. Investigation of the inhibition of leukotriene A4 hydrolase. Bioorganic & Medicinal Chemistry. 3: 969-995. PMID 7582974 DOI: 10.1016/0968-0896(95)00078-U  0.317
1995 Wong CH. Enzymatic and chemo-enzymatic synthesis of carbohydrates Pure and Applied Chemistry. 67: 1609-1616. DOI: 10.1351/Pac199567101609  0.389
1995 Chou W, Fotsch C, Wong C. Synthesis of Nitrocyclitols Based on Enzymic Aldol Reaction and Intramolecular Nitroaldol Reaction Journal of Organic Chemistry. 60: 2916-2917. DOI: 10.1021/Jo00114A051  0.308
1995 Wong C, Provencher L, Porco JA, Jung S, Wang Y, Chen L, Wang R, Steensma DH. Synthesis and Evaluation of Homoaza Sugars as Glycosidase Inhibitors Journal of Organic Chemistry. 60: 1492-1501. DOI: 10.1021/Jo00111A007  0.552
1995 Lin C, Shen G, Garcia-Junceda E, Wong C. Enzymatic Synthesis And Regeneration Of 3'-Phosphoadenosine 5'-Phosphosulfate (Paps) For Regioselective Sulfation Of Oligosaccharides Journal of the American Chemical Society. 117: 8031-8032. DOI: 10.1021/Ja00135A028  0.348
1995 Luca CD, Lansing M, Martini I, Crescenzi F, Shen G, O'Regan M, Wong C. Enzymic Synthesis of Hyaluronic Acid with Regeneration of Sugar Nucleotides Journal of the American Chemical Society. 117: 5869-5870. DOI: 10.1021/Ja00126A034  0.303
1995 Wong C, Garcia-Junceda E, Chen L, Blanco O, Gijsen HJM, Steensma DH. Recombinant 2-Deoxyribose-5-phosphate Aldolase in Organic Synthesis: Use of Sequential Two-Substrate and Three-Substrate Aldol Reactions Journal of the American Chemical Society. 117: 3333-3339. DOI: 10.1021/Ja00117A003  0.31
1995 Hiranuma S, Shimizu T, Nakata T, Kajimoto T, Wong C. Synthesis and inhibition analysis of five-membered homoazasugars from D-arabinofuranose via an SN2 reaction of the chloromethylsulfonate Tetrahedron Letters. 36: 8247-8250. DOI: 10.1016/0040-4039(95)01769-E  0.33
1995 Gijsen HJM, Wong CH. Synthesis of a cyclitol via a tandem enzymatic aldol - intramolecular Horner-Wadsworth-Emmons reaction Tetrahedron Letters. 36: 7057-7060. DOI: 10.1016/0040-4039(95)01483-X  0.3
1995 Vassilev VP, Uchiyama T, Kajimoto T, Wong C. An efficient chemo-enzymatic synthesis of α-amino-β-hydroxy-γ-butyrolactone Tetrahedron Letters. 36: 5063-5064. DOI: 10.1016/0040-4039(95)00924-2  0.305
1995 Wong C, Halcomb RL, Ichikawa Y, Kajimoto T. Enzymes in Organic Synthesis: Application to the Problems of Carbohydrate Recognition(Part 1) Angewandte Chemie International Edition in English. 34: 412-432. DOI: 10.1002/Anie.199504121  0.353
1994 Marquardt JL, Brown ED, Lane WS, Haley TM, Ichikawa Y, Wong CH, Walsh CT. Kinetics, stoichiometry, and identification of the reactive thiolate in the inactivation of UDP-GlcNAc enolpyruvoyl transferase by the antibiotic fosfomycin. Biochemistry. 33: 10646-51. PMID 8075065 DOI: 10.1021/Bi00201A011  0.468
1994 Aoki S, Kondo H, Wong C. [13] Glycosyl phosphites as glycosylation reagents Methods in Enzymology. 247: 193-211. PMID 7898353 DOI: 10.1016/S0076-6879(94)47015-4  0.364
1994 Ichikawa Y, Wang R, Wong C. Regeneration of sugar nucleotide for enzymatic oligosaccharide synthesis. Methods in Enzymology. 247: 107-127. PMID 7898347 DOI: 10.1016/S0076-6879(94)47009-X  0.359
1994 Fang J, Wong C. Enzymes in Organic Synthesis: Alteration of Reversible Reactions to Irreversible Processes Synlett. 1994: 393-402. DOI: 10.1055/S-1994-22864  0.307
1994 Herrmann GF, Wang P, Shen G, Garcia-Junceda E, Khan SH, Matta KL, Wong C. Large scale production of recombinant .alpha.-1,2-mannosyltransferase from E. coli for the study of acceptor specificity and use of the recombinant whole cells in synthesis The Journal of Organic Chemistry. 59: 6356-6362. DOI: 10.1021/Jo00100A043  0.309
1994 Kondo H, Aoki S, Ichikawa Y, Halcomb RL, Ritzen H, Wong C. Glycosyl Phosphites as Glycosylation Reagents: Scope and Mechanism The Journal of Organic Chemistry. 59: 864-877. DOI: 10.1021/Jo00083A032  0.335
1994 Henderson I, Sharpless KB, Wong C. Synthesis of Carbohydrates Via Tandem Use of the Osmium-Catalyzed Asymmetric Dihydroxylation and Enzyme-Catalyzed Aldol Addition-Reactions Journal of the American Chemical Society. 116: 558-561. DOI: 10.1021/Ja00081A016  0.365
1994 Henderson I, Laslo K, Wong CH. Chemoenzymatic synthesis of homoazasugars Tetrahedron Letters. 35: 359-362. DOI: 10.1016/0040-4039(94)85053-4  0.328
1993 Yuan W, Munoz B, Wong C, Haeggström JZ, Wetterholm A, Samuelsson B. Development of selective tight-binding inhibitors of leukotriene A4 hydrolase Journal of Medicinal Chemistry. 36: 211-220. PMID 8423594 DOI: 10.1021/Jm00054A004  0.31
1993 Wong C, Ichikawa Y, Kajimoto T, Liu KK, Shen G, Lin C, Wang Y, Dumas DP, Lin Y, Wang R, Look GC. Practical synthesis of carbohydrates based on aldolases and glycosyl transferases Pure and Applied Chemistry. 65: 803-808. DOI: 10.1351/Pac199365040803  0.364
1993 Herrmann GF, Ichikawa Y, Wandrey C, Gaeta FCA, Paulson JC, Wong CH. A new multi-enzyme system for a one-pot synthesis of sialyl oligosaccharides: Combined use of β-galactosidase and α(26)-sialyltransferase coupled with regeneration in situ of CMP-sialic acid Tetrahedron Letters. 34: 3091-3094. DOI: 10.1016/S0040-4039(00)93387-2  0.316
1993 Halcomb RL, Wong CH. Synthesis of oligosaccharides, glycopeptides, and glycolipids Current Opinion in Structural Biology. 3: 694-700. DOI: 10.1016/0959-440X(93)90052-M  0.368
1993 Yi-Fong W, David DP, Wong C. Chemo-enzymatic synthesis of five-membered azasugars as inhibitors of fucosidase and fucosyltransferase: An issue regarding the stereochemistry discrimination at transition states Tetrahedron Letters. 34: 403-406. DOI: 10.1016/0040-4039(93)85087-D  0.308
1992 Ichikawa Y, Look GC, Wong C. Enzyme-catalyzed oligosaccharide synthesis. Analytical Biochemistry. 202: 215-238. PMID 1519746 DOI: 10.1016/0003-2697(92)90099-S  0.366
1992 Wong C, Liu KK‐, Kajimoto T, Chen L, Zhong Z, Ichikawa Y, Shen G. Developing better enzymes for organic synthesis. Annals of the New York Academy of Sciences. 672: 343-351. PMID 1476380 DOI: 10.1111/J.1749-6632.1992.Tb32700.X  0.301
1992 Wong CH. Engineering enzymes for chemoenzymatic synthesis Part 2: modifying proteases for peptide synthesis Trends in Biotechnology. 10: 378-381. PMID 1368879 DOI: 10.1016/0167-7799(92)90276-2  0.307
1992 Ichikawa Y, Look GC, Wong C. Synthesis of Oligosaccharides Using Glycosyltransferases Journal of Synthetic Organic Chemistry Japan. 50: 441-450. DOI: 10.5059/Yukigoseikyokaishi.50.441  0.351
1992 Wong C, Liu KK-, Kajimoto T, Chen L, Zhong Z, Dumas DP, Liu JL-, Ichikawa Y, Shen G-. Enzymes for carbohydrate and peptide syntheses Pure and Applied Chemistry. 64: 1197-1202. DOI: 10.1351/Pac199264081197  0.325
1992 Ichikawa Y, Lin Y, Dumas DP, Shen G, Garcia-Junceda E, Williams MA, Bayer R, Ketcham C, Walker LE, Paulson JC, Wong C. Chemical-Enzymatic Synthesis and Conformational-Analysis of Sialyl Lewis-X and Derivatives Journal of the American Chemical Society. 114: 9283-9298. DOI: 10.1021/Ja00050A007  0.317
1992 Look GC, Wong CH. A facile enzymatic synthesis of galβ1,3glucal: a key intermediate for the synthesis of Lea and sialyl Lea Tetrahedron Letters. 33: 4253-4256. DOI: 10.1016/S0040-4039(00)74231-6  0.307
1991 Drueckhammer DG, Hennen WJ, Pederson RL, Barbas CF, Gautheron CM, Krach T, Wong CH. Enzyme catalysis in synthetic carbohydrate chemistry Synthesis. 499-525. DOI: 10.1055/S-1991-26506  0.672
1990 von der Osten CH, Gioannetti C, Barbas C, Pederson RL, Wang YF, Wong CH, Ozaki A, Toone E, Whitesides GM, Sinskey AJ. Molecular cloning of aldolases for synthetic applications. Annals of the New York Academy of Sciences. 613: 771-5. PMID 2076016 DOI: 10.1111/J.1749-6632.1990.Tb18262.X  0.646
1990 WONG C, DRUECKHAMMER DG, DURRWACHTER JR, LACHER B, CHAUVET CJ, WANG Y, SWEERS HM, SMITH GL, YANG LJ, HENNEN WJ. ChemInform Abstract: Enzyme-Catalyzed Synthesis of Carbohydrates Cheminform. 21. DOI: 10.1002/chin.199033344  0.628
1989 Wong CH. Enzymatic catalysts in organic synthesis Science. 244: 1145-1152. PMID 2658059 DOI: 10.1126/Science.2658059  0.346
1989 Wong C, L. Pederson R. Enzymatic Aldol Condensation as a Route to Heterocycles: Synthesis of 1,4-Dideoxy-1,4-imino-D-arabinitol, Fagomine, 1-Deoxynojirimycin and 1-Deoxymannojirimycin Heterocycles. 28: 477. DOI: 10.3987/Com-88-S99  0.309
1989 Bibbs JA, Zhong Z, Wong C. Modification of Proteases for Peptide Synthesis Mrs Proceedings. 174. DOI: 10.1557/Proc-174-223  0.334
1989 Drueckhammer DG, Durrwachter JR, Pederson RL, Crans DC, Daniels L, Wong CH. Reversible and in situ formation of organic arsenates and vanadates as organic phosphate mimics in enzymatic reactions: Mechanistic investigation of aldol reactions and synthetic applications Journal of Organic Chemistry. 54: 70-77. DOI: 10.1021/Jo00262A021  0.677
1989 Wanc Y, Wong C. Enantioselective Syntheses of Plate Let-Activating Factor and a Phospholipase A2Inhibitor from Chiral Synthons Prepared Enzymatically Journal of the Chinese Chemical Society. 36: 463-468. DOI: 10.1002/Jccs.198900064  0.311
1989 Chen S, Wong C. Studies on Angiotensin-Converting Enzyme Inhibitors: Protease Catalyzed Resolution of Aryl 3-Mercapto-2-Methylpropionic Ester Journal of the Chinese Chemical Society. 36: 451-458. DOI: 10.1002/Jccs.198900062  0.318
1988 Pederson RL, Kim M, Wong C. A combined chemical and enzymatic procedure for the synthesis of 1-deoxynojirimycin and 1-deoxymannojirimycin Tetrahedron Letters. 29: 4645-4648. DOI: 10.1016/S0040-4039(00)80570-5  0.345
1987 Crans DC, Kazlauskas RJ, Hirschbein BL, Wong CH, Abril O, Whitesides GM. Enzymatic regeneration of adenosine 5'-triphosphate: acetyl phosphate, phosphoenolpyruvate, methoxycarbonyl phosphate, dihydroxyacetone phosphate, 5-phospho-alpha-D-ribosyl pyrophosphate, uridine-5'-diphosphoglucose. Methods in Enzymology. 136: 263-80. PMID 2446104 DOI: 10.1016/S0076-6879(87)36027-6  0.696
1987 Matos J, Raushel F, Wong C. S-adenosylmethionine: studies on chemical and enzymatic synthesis. Biotechnology and Applied Biochemistry. 9: 39-52. DOI: 10.1111/J.1470-8744.1987.Tb00461.X  0.348
1987 Barbas CF, Wong CH. Papain catalysed peptide synthesis: Control of amidase activity and the introduction of unusual amino acids Journal of the Chemical Society, Chemical Communications. 533-534. DOI: 10.1039/C39870000533  0.303
1987 Drueckhammer DG, Sadozai SK, Wong CH, Roberts SM. Biphasic one-pot synthesis of two useful and separable compounds using nicotinamide cofactor-requiring enzymes: Syntheses of (S)-4-hydroxyhexanoate and its lactone Enzyme and Microbial Technology. 9: 564-570. DOI: 10.1016/0141-0229(87)90089-5  0.62
1986 Durrwachter JR, Drueckhammer DG, Nozaki K, Sweers HM, Wong CH. Enzymic aldol condensation/isomerization as a route to unusual sugar derivatives. Journal of the American Chemical Society. 108: 7812-8. PMID 22283291 DOI: 10.1021/Ja00284A053  0.642
1986 West JB, Wong CH. Enzyme-catalysed synthesis of peptides containing D-amino acids Journal of the Chemical Society, Chemical Communications. 417-418. DOI: 10.1039/C39860000417  0.316
1985 Wong CH, Drueckhammer DG. Enzymatic synthesis of chiral hydroxy compounds using immobilized glucose dehydrogenase from Bacillus cereus for NAD(P)H regeneration Bio/Technology. 3: 649-651. DOI: 10.1038/Nbt0785-649  0.648
1985 Wong C, Drueckhammer DG, Sweers HM. Enzymatic vs. fermentative synthesis: thermostable glucose dehydrogenase catalyzed regeneration of NAD(P)H for use in enzymatic synthesis Journal of the American Chemical Society. 107: 4028-4031. DOI: 10.1021/Ja00299A044  0.643
1985 Whitesides GM, Wong C. Enzymes as Catalysts in Synthetic Organic Chemistry [New Synthetic Methods (53)] Angewandte Chemie. 24: 617-638. DOI: 10.1002/Anie.198506173  0.498
1985 Whitesides GM, Wong C. Enzyme in der organischen Synthese Angewandte Chemie. 97: 617-638. DOI: 10.1002/Ange.19850970804  0.497
1982 Wong CH, Pollak A, McCurry SD, Sue JM, Knowles JR, Whitesides GM. Synthesis of ribulose 1,5-bisphosphate: routes from glucose 6-phosphate (via 6-phosphogluconate) and from adenosine monophosphate (via ribose 5-phosphate). Methods in Enzymology. 89: 108-21. PMID 7144568 DOI: 10.1016/S0076-6879(82)89020-4  0.52
1981 DiCosimo R, Wong C, Daniels L, Whitesides GM. Enzyme-catalyzed organic synthesis: electrochemical regeneration of NAD(P)H from NAD(P) using methyl viologen and flavoenzymes The Journal of Organic Chemistry. 46: 4622-4623. DOI: 10.1021/Jo00335A078  0.496
1981 Wong CH, Daniels L, Orme-Johnson WH, Whitesides GM. Enzyme-catalyzed organic synthesis: NAD(P)H regeneration using dihydrogen and the hydrogenase from Methanobacterium thermoautotrophicum Journal of the American Chemical Society. 103: 6227-6228. DOI: 10.1021/Ja00410A049  0.505
1981 Wong C, Whitesides GM. Enzyme-catalyzed organic synthesis: NAD(P)H cofactor regeneration by using glucose-6-phosphate and the glucose-5-phosphate dehydrogenase from Leuconostoc mesenteroides Journal of the American Chemical Society. 103: 4890-4899. DOI: 10.1021/Ja00406A037  0.485
1980 Wong C, McCurry SD, Whitesides GM. Practical enzymic syntheses of ribulose 1,5 bisphosphate and ribose 5-phosphate Journal of the American Chemical Society. 102: 7938-7939. DOI: 10.1021/Ja00547A023  0.485
1979 Chou S, Wong C, Chen S, Wang K. Enzymatic Synthesis of Oligopeptide. Part II. Synthesis of Bis(N-Protected Amino Acid) Hydrazides by Papain Journal of the Chinese Chemical Society. 26: 11-15. DOI: 10.1002/Jccs.197900003  0.315
1978 Chou S, Chen S, Wong C, Wang K. Enzymatic Synthesis of Oligopeptide. Part I. Papain-Catalyzed Synthesis of Dipeptide, Tripeptide and Tetrapeptide Journal of the Chinese Chemical Society. 25: 215-218. DOI: 10.1002/Jccs.197800035  0.325
Low-probability matches (unlikely to be authored by this person)
2015 Lin CW, Tsai MH, Li ST, Tsai TI, Chu KC, Liu YC, Lai MY, Wu CY, Tseng YC, Shivatare SS, Wang CH, Chao P, Wang SY, Shih HW, Zeng YF, ... ... Wong CH, et al. A common glycan structure on immunoglobulin G for enhancement of effector functions. Proceedings of the National Academy of Sciences of the United States of America. PMID 26253764 DOI: 10.1073/Pnas.1513456112  0.3
1999 Sears P, Wong CH. Carbohydrate Mimetics: A New Strategy for Tackling the Problem of Carbohydrate-Mediated Biological Recognition. Angewandte Chemie (International Ed. in English). 38: 2300-2324. PMID 10458780 DOI: 10.1002/(Sici)1521-3773(19990816)38:16<2300::Aid-Anie2300>3.0.Co;2-6  0.299
1998 Kanemitsu T, Kanie O, Wong CH. Quantitative Monitoring of Solid-Phase Synthesis Using Gated Decoupling C NMR Spectroscopy with a C-Enriched Protecting Group and an Internal Standard in the Synthesis of Sialyl Lewis Tetrasaccharide. Angewandte Chemie (International Ed. in English). 37: 3415-3418. PMID 29711282 DOI: 10.1002/(Sici)1521-3773(19981231)37:24<3415::Aid-Anie3415>3.0.Co;2-8  0.299
2010 Lewis JC, Mantovani SM, Fu Y, Snow CD, Komor RS, Wong CH, Arnold FH. Combinatorial alanine substitution enables rapid optimization of cytochrome P450BM3 for selective hydroxylation of large substrates. Chembiochem : a European Journal of Chemical Biology. 11: 2502-5. PMID 21108271 DOI: 10.1002/Cbic.201000565  0.298
1996 Orsat B, Alper PB, Moree W, Mak C, Wong C. Homocarbonates as Substrates for the Enantioselective Enzymatic Protection of Amines Journal of the American Chemical Society. 118: 712-713. DOI: 10.1021/Ja9533048  0.298
2005 Tolbert TJ, Franke D, Wong CH. A new strategy for glycoprotein synthesis: ligation of synthetic glycopeptides with truncated proteins expressed in E. coli as TEV protease cleavable fusion protein. Bioorganic & Medicinal Chemistry. 13: 909-15. PMID 15653356 DOI: 10.1016/J.Bmc.2004.06.047  0.298
2011 Chou CY, Ko TP, Wu KJ, Huang KF, Lin CH, Wong CH, Wang AH. Modulation of substrate specificities of D-sialic acid aldolase through single mutations of Val-251. The Journal of Biological Chemistry. 286: 14057-64. PMID 21270125 DOI: 10.1074/Jbc.M110.179465  0.298
2004 Durón SG, Polat T, Wong CH. N-(phenylthio)-epsilon-caprolactam: a new promoter for the activation of thioglycosides. Organic Letters. 6: 839-41. PMID 14986988 DOI: 10.1021/Ol0400084  0.298
2018 Liu CP, Tsai TI, Cheng T, Shivatare VS, Wu CY, Wu CY, Wong CH. Glycoengineering of antibody (Herceptin) through yeast expression and in vitro enzymatic glycosylation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29311294 DOI: 10.1073/Pnas.1718172115  0.297
1994 Gijsen HJM, Wong C. Unprecedented Asymmetric Aldol Reactions with Three Aldehyde Substrates Catalyzed by 2-Deoxyribose-5-phosphate Aldolase Journal of the American Chemical Society. 116: 8422-8423. DOI: 10.1021/Ja00097A082  0.297
1991 Barbas CF, Wong CH. Overexpression and substrate specificity studies of phosphodeoxyribomutase and thymidine phosphorylase Bioorganic Chemistry. 19: 261-269. DOI: 10.1016/0045-2068(91)90051-P  0.297
2003 Mak CC, Brik A, Lerner DL, Elder JH, Morris GM, Olson AJ, Wong CH. Design and synthesis of broad-based mono- and bi- cyclic inhibitors of FIV and HIV proteases. Bioorganic & Medicinal Chemistry. 11: 2025-40. PMID 12670654 DOI: 10.1016/S0968-0896(03)00054-3  0.297
2012 Lenger J, Schröder M, Ennemann EC, Müller B, Wong CH, Noll T, Dierks T, Hanson SR, Sewald N. Evaluation of sulfatase-directed quinone methide traps for proteomics. Bioorganic & Medicinal Chemistry. 20: 622-7. PMID 21570853 DOI: 10.1016/J.Bmc.2011.04.044  0.297
1998 Kanie Y, Kirsch A, Kanie O, Wong C. Enzymatic Assay of Galactosyltransferase by Capillary Electrophoresis Analytical Biochemistry. 263: 240-245. PMID 9799537 DOI: 10.1006/Abio.1998.2762  0.296
1997 Kim M, Lim IT, Kim H, Wong C. Enzymatic single aldol reactions of remote dialdehydes Tetrahedron-Asymmetry. 8: 1507-1509. DOI: 10.1016/S0957-4166(97)00139-0  0.296
2017 Andrabi R, Su CY, Liang CH, Shivatare SS, Briney B, Voss JE, Nawazi SK, Wu CY, Wong CH, Burton DR. Glycans Function as Anchors for Antibodies and Help Drive HIV Broadly Neutralizing Antibody Development. Immunity. PMID 28916265 DOI: 10.1016/J.Immuni.2017.08.006  0.295
1994 Munoz B, Giam C, Wong C. α-Ketoamide Phe—Pro isostere as a new core structure for the inhibition of HIV protease Bioorganic & Medicinal Chemistry. 2: 1085-1090. PMID 7773625 DOI: 10.1016/S0968-0896(00)82058-1  0.295
2005 Wong CH. Protein glycosylation: New challenges and opportunities Journal of Organic Chemistry. 70: 4219-4225. PMID 15903293 DOI: 10.1021/Jo050278F  0.295
2004 Franke D, Hsu C, Wong C. Directed evolution of aldolases. Methods in Enzymology. 388: 224-238. PMID 15289075 DOI: 10.1016/S0076-6879(04)88020-0  0.295
2006 Liu L, Hong ZY, Wong CH. Convergent glycopeptide synthesis by traceless Staudinger ligation and enzymatic coupling. Chembiochem : a European Journal of Chemical Biology. 7: 429-32. PMID 16444769 DOI: 10.1002/Cbic.200500437  0.295
1978 Wong C, Chen S, Ho C, Wang K. Synthesis of a fully active snake venom cardiotoxin by fragment condensation on solid polymer Biochimica Et Biophysica Acta. 536: 376-389. PMID 81691 DOI: 10.1016/0005-2795(78)90496-8  0.295
2014 Huang LY, Huang SH, Chang YC, Cheng WC, Cheng TJ, Wong CH. Enzymatic synthesis of lipid II and analogues. Angewandte Chemie (International Ed. in English). 53: 8060-5. PMID 24990652 DOI: 10.1002/Anie.201402313  0.295
2005 Hsu CC, Hong Z, Wada M, Franke D, Wong CH. Directed evolution of D-sialic acid aldolase to L-3-deoxy-manno-2-octulosonic acid (L-KDO) aldolase. Proceedings of the National Academy of Sciences of the United States of America. 102: 9122-6. PMID 15967977 DOI: 10.1073/Pnas.0504033102  0.295
2002 Mitchell ML, Lee LV, Wong CH. Synthesis and evaluation of six-membered GDP-iminocyclitol Tetrahedron Letters. 43: 5691-5693. DOI: 10.1016/S0040-4039(02)01108-5  0.294
1995 Wong C, Alajarin R, Moris-Varas F, Blanco O, Garcia-Junceda E. Enzymic Synthesis of L-Fucose and Analogs Journal of Organic Chemistry. 60: 7360-7363. DOI: 10.1021/Jo00127A052  0.293
1997 Kaneko M, Kanie O, Kajimoto T, Wong C. Toward a transition state analog inhibitor of N-acetylglucosaminyl transferase V Bioorganic & Medicinal Chemistry Letters. 7: 2809-2812. DOI: 10.1016/S0960-894X(97)10087-7  0.293
1996 Qian X, Morís-Varas F, Fitzgerald MC, Wong CH. C2-symmetrical tetrahydroxyazepanes as inhibitors of glycosidases and HIV/FIV proteases. Bioorganic & Medicinal Chemistry. 4: 2055-69. PMID 9022971 DOI: 10.1016/S0968-0896(96)00218-0  0.293
2001 Yu CS, Niikura K, Lin CC, Wong CH. The Thioglycoside and Glycosyl Phosphite of 5-Azido Sialic Acid: Excellent Donors for the α-Glycosylation of Primary Hydroxy Groups. Angewandte Chemie (International Ed. in English). 40: 2900-2903. PMID 29711986 DOI: 10.1002/1521-3773(20010803)40:15<2900::Aid-Anie2900>3.0.Co;2-4  0.292
2001 Heine A, DeSantis G, Luz JG, Mitchell M, Wong CH, Wilson IA. Observation of covalent intermediates in an enzyme mechanism at atomic resolution. Science (New York, N.Y.). 294: 369-74. PMID 11598300 DOI: 10.1126/Science.1063601  0.292
1996 Qiao L, Murray BW, Shimazaki M, Schultz J, Wong C. Synergistic Inhibition of Human α-1,3-Fucosyltransferase V Journal of the American Chemical Society. 118: 7653-7662. DOI: 10.1021/Ja960274F  0.292
1998 Lampe TFJ, Weitz-Schmidt G, Wong CH. Parallel Synthesis of Sialyl Lewis X Mimetics on a Solid Phase: Access to a Library of Fucopeptides. Angewandte Chemie (International Ed. in English). 37: 1707-1711. PMID 29711524 DOI: 10.1002/(Sici)1521-3773(19980703)37:12<1707::Aid-Anie1707>3.0.Co;2-V  0.292
1991 Pederson RL, Esker J, Wong C. An improved synthesis of dihydroxyacetone phosphate Tetrahedron. 47: 2643-2648. DOI: 10.1016/S0040-4020(01)81796-8  0.291
1997 Moree WJ, Sears P, Kawashiro K, Witte K, Wong CH. Exploitation of subtilisin BPN' as catalyst for the synthesis of peptides containing noncoded amino acids, peptide mimetics and peptide conjugates Journal of the American Chemical Society. 119: 3942-3947. DOI: 10.1021/Ja964399W  0.291
2016 Wu TN, Lin KH, Wu YT, Huang JR, Hung JT, Wu JC, Chen CY, Chu KC, Lin NH, Yu AL, Wong CH. Phenyl Glycolipids with Different Glycosyl Groups Exhibit Marked Differences in Murine and Human iNKT Cell Activation. Acs Chemical Biology. PMID 27782396 DOI: 10.1021/Acschembio.6B00650  0.291
2000 Node M, Nishide K, Shibata K, Fujita T, Kajimoto T, Wong C. An Asymmetrical Total Synthesis of a Potent Immunosuppressant,Mycestericins D and F,through an Aldol Reaction Using L-Threonine Aldolase Heterocycles. 52: 1191-1201. DOI: 10.3987/Com-99-S117  0.291
1994 Schuster M, Wang P, Paulson JC, Wong C. Solid-Phase Chemical-Enzymic Synthesis of Glycopeptides and Oligosaccharides Journal of the American Chemical Society. 116: 1135-1136. DOI: 10.1021/Ja00082A047  0.291
1999 Takebayashi M, Hiranuma S, Kanie Y, Kajimoto T, Kanie O, Wong C. A Versatile Synthetic Strategy for the Preparation and Discovery of New Iminocyclitols as Inhibitors of Glycosidases Journal of Organic Chemistry. 64: 5280-5291. DOI: 10.1021/Jo9902446  0.29
1997 Seitz O, Wong CH. Chemoenzymatic solution- and solid-phase synthesis of O-glycopeptides of the mucin domain of MAdCAM-1. A general route to O-LacNAc, O-sialyl-LacNAc, and O-Sialyl-Lewis-X peptides Journal of the American Chemical Society. 119: 8766-8776. DOI: 10.1021/Ja971383C  0.29
2017 Tsai TI, Li ST, Liu CP, Chen KY, Shivatare SS, Lin CW, Liao SF, Lin CW, Hsu TL, Wu YT, Tsai MH, Lai MY, Lin NH, Wu CY, Wong CH. An Effective Bacterial Fucosidase for Glycoprotein Remodeling. Acs Chemical Biology. 12: 63-72. PMID 28103685 DOI: 10.1021/Acschembio.6B00821  0.29
1994 Yuasa H, Kajimoto T, Wong C. Synthesis of iminothiasugar as a potential transition-state analog inhibitor of glycosyltransfer reactions Tetrahedron Letters. 35: 8243-8246. DOI: 10.1016/0040-4039(94)88293-2  0.29
2018 Wu WS, Cheng WC, Cheng TR, Wong CH. Affinity-Based Screen for Inhibitors of Bacterial Transglycosylase. Journal of the American Chemical Society. PMID 29411975 DOI: 10.1021/Jacs.7B13205  0.289
2005 Fan G, Pan Y, Lu K, Cheng Y, Lin W, Lin S, Lin C, Wong C, Fang J, Lin C. Synthesis of α-galactosyl ceramide and the related glycolipids for evaluation of their activities on mouse splenocytes Tetrahedron. 61: 1855-1862. DOI: 10.1016/J.Tet.2004.12.027  0.289
1988 Barbas CF, Wong CH. One-pot tripeptide syntheses from three single amino acid derivatives catalyzed by papain Tetrahedron Letters. 29: 2907-2910. DOI: 10.1016/0040-4039(88)85044-5  0.289
2004 Klostermeier D, Sears P, Wong CH, Millar DP, Williamson JR. A three-fluorophore FRET assay for high-throughput screening of small-molecule inhibitors of ribosome assembly. Nucleic Acids Research. 32: 2707-15. PMID 15148358 DOI: 10.1093/Nar/Gkh588  0.288
1992 Wong CH. Engineering enzymes for chemoenzymatic synthesis Part I: practical routes to aza-sugars and complex carbohydrates Trends in Biotechnology. 10: 337-341. PMID 1368872 DOI: 10.1016/0167-7799(92)90264-V  0.288
1996 Marron TG, Woltering TJ, Weitz-Schmidt G, Wong C. C-Mannose derivatives as potent mimics of sialyl Lewis X Tetrahedron Letters. 37: 9037-9040. DOI: 10.1016/S0040-4039(96)02124-7  0.288
1997 Lin C, Lin C, Wong C. Sialic acid aldolase-catalyzed condensation of pyruvate and N-substituted mannosamine: A useful method for the synthesis of N-substituted sialic acids Tetrahedron Letters. 38: 2649-2652. DOI: 10.1016/S0040-4039(97)00442-5  0.288
2005 Wong CH. A wide range of strategies yields new enzymatic reactions and processes Advanced Synthesis and Catalysis. 347: 901. DOI: 10.1002/Adsc.200505112  0.288
2008 Giffin MJ, Heaslet H, Brik A, Lin YC, Cauvi G, Wong CH, McRee DE, Elder JH, Stout CD, Torbett BE. A copper(I)-catalyzed 1,2,3-triazole azide-alkyne click compound is a potent inhibitor of a multidrug-resistant HIV-1 protease variant. Journal of Medicinal Chemistry. 51: 6263-70. PMID 18823110 DOI: 10.1021/Jm800149M  0.288
1991 Gautheron-Le Narvor C, Wong CH. Glycosyltransferase-catalysed stereoselective glycosidation of monosaccharide-based glycosidase inhibitors: A new approach to the synthesis of sequence-specific glycosidase inhibitors Journal of the Chemical Society, Chemical Communications. 1130-1131. DOI: 10.1039/C39910001130  0.288
2015 Lusvarghi S, Ghirlando R, Wong CH, Bewley CA. Glycopeptide mimetics recapitulate high-mannose-type oligosaccharide binding and function. Angewandte Chemie (International Ed. in English). 54: 5603-8. PMID 25776945 DOI: 10.1002/Anie.201500157  0.287
1998 Hiruma K, Kanie O, Wong C. Synthesis of analogs of 1,1-linked galactosyl mannoside as mimetics of sialyl Lewis X tetrasaccharide Tetrahedron. 54: 15781-15792. DOI: 10.1016/S0040-4020(98)00990-9  0.287
2012 Huang CY, Shih HW, Lin LY, Tien YW, Cheng TJ, Cheng WC, Wong CH, Ma C. Crystal structure of Staphylococcus aureus transglycosylase in complex with a lipid II analog and elucidation of peptidoglycan synthesis mechanism. Proceedings of the National Academy of Sciences of the United States of America. 109: 6496-501. PMID 22493270 DOI: 10.1073/Pnas.1203900109  0.287
1995 Fang J, Lin C, Bradshaw CW, Wong C. Enzymes in organic synthesis: oxidoreductions Journal of the Chemical Society-Perkin Transactions 1. 967-978. DOI: 10.1039/P19950000967  0.287
2010 Cheng TJ, Wu YT, Yang ST, Lo KH, Chen SK, Chen YH, Huang WI, Yuan CH, Guo CW, Huang LY, Chen KT, Shih HW, Cheng YS, Cheng WC, Wong CH. High-throughput identification of antibacterials against methicillin-resistant Staphylococcus aureus (MRSA) and the transglycosylase. Bioorganic & Medicinal Chemistry. 18: 8512-29. PMID 21075637 DOI: 10.1016/J.Bmc.2010.10.036  0.287
1999 Mao S, Gao C, Lo CH, Wirsching P, Wong CH, Janda KD. Phage-display library selection of high-affinity human single-chain antibodies to tumor-associated carbohydrate antigens sialyl Lewisx and Lewisx. Proceedings of the National Academy of Sciences of the United States of America. 96: 6953-8. PMID 10359820 DOI: 10.1073/Pnas.96.12.6953  0.287
2001 Burkhart F, Zhang Z, Wacowich-Sgarbi S, Wong C. Synthesis of the Globo H Hexasaccharide Using the Programmable Reactivity-Based One-Pot Strategy Angewandte Chemie. 113: 1314-1317. DOI: 10.1002/1521-3773(20010401)40:7<1274::Aid-Anie1274>3.0.Co;2-W  0.287
2016 Sok D, Pauthner M, Briney B, Lee JH, Saye-Francisco KL, Hsueh J, Ramos A, Le KM, Jones M, Jardine JG, Bastidas R, Sarkar A, Liang CH, Shivatare SS, Wu CY, ... ... Wong CH, et al. A Prominent Site of Antibody Vulnerability on HIV Envelope Incorporates a Motif Associated with CCR5 Binding and Its Camouflaging Glycans. Immunity. 45: 31-45. PMID 27438765 DOI: 10.1016/J.Immuni.2016.06.026  0.287
1995 Huang H, Wong C. Synthesis of Biologically Active Sialyl Lewis X Mimetics Journal of Organic Chemistry. 60: 3100-3106. DOI: 10.1021/Jo00115A027  0.286
2005 Shie JJ, Fang JM, Kuo TH, Kuo CJ, Liang PH, Huang HJ, Wu YT, Jan JT, Cheng YS, Wong CH. Inhibition of the severe acute respiratory syndrome 3CL protease by peptidomimetic alpha,beta-unsaturated esters. Bioorganic & Medicinal Chemistry. 13: 5240-52. PMID 15994085 DOI: 10.1016/J.Bmc.2005.05.065  0.286
2007 Yu Z, Sawkar AR, Whalen LJ, Wong CH, Kelly JW. Isofagomine- and 2,5-anhydro-2,5-imino-D-glucitol-based glucocerebrosidase pharmacological chaperones for Gaucher disease intervention. Journal of Medicinal Chemistry. 50: 94-100. PMID 17201413 DOI: 10.1021/Jm060677I  0.286
2001 Bühler B, Lin Y, Morris G, Olson AJ, Wong C, Richman DD, Elder JH, Torbett BE. Viral evolution in response to the broad-based retroviral protease inhibitor TL-3 Journal of Virology. 75: 9502-9508. PMID 11533212 DOI: 10.1128/Jvi.75.19.9502-9508.2001  0.286
2006 Cheng YS, Lo KH, Hsu HH, Shao YM, Yang WB, Lin CH, Wong CH. Screening for HIV protease inhibitors by protection against activity-mediated cytotoxicity in Escherichia coli. Journal of Virological Methods. 137: 82-7. PMID 16849028 DOI: 10.1016/J.Jviromet.2006.06.003  0.286
1995 Gijsen HJM, Wong C. Sequential One-Pot Aldol Reactions Catalyzed By 2-Deoxyribose-5-Phosphate Aldolase And Fructose-1,6-Diphosphate Aldolase Journal of the American Chemical Society. 117: 2947-2948. DOI: 10.1021/Ja00115A038  0.285
2010 Wen WH, Wang SY, Tsai KC, Cheng YS, Yang AS, Fang JM, Wong CH. Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses. Bioorganic & Medicinal Chemistry. 18: 4074-84. PMID 20452227 DOI: 10.1016/J.Bmc.2010.04.010  0.285
1978 Wong C, Ho C, Wang K. Purification of synthetic cardiotoxin by affinity chromatography Journal of Chromatography A. 154: 13-23. PMID 670366 DOI: 10.1016/S0021-9673(00)88476-9  0.285
2019 Chen X, Wong CH, Ma C. Targeting the Bacterial Transglycosylase: Antibiotic Development from a Structural Perspective. Acs Infectious Diseases. PMID 31283163 DOI: 10.1021/Acsinfecdis.9B00118  0.285
2010 Lin KH, Liang JJ, Huang WI, Lin-Chu SY, Su CY, Lee YL, Jan JT, Lin YL, Cheng YS, Wong CH. In vivo protection provided by a synthetic new alpha-galactosyl ceramide analog against bacterial and viral infections in murine models. Antimicrobial Agents and Chemotherapy. 54: 4129-36. PMID 20660669 DOI: 10.1128/Aac.00368-10  0.285
2007 Hanson SR, Hsu TL, Weerapana E, Kishikawa K, Simon GM, Cravatt BF, Wong CH. Tailored glycoproteomics and glycan site mapping using saccharide-selective bioorthogonal probes. Journal of the American Chemical Society. 129: 7266-7. PMID 17506567 DOI: 10.1021/Ja0724083  0.285
2009 Sung MT, Lai YT, Huang CY, Chou LY, Shih HW, Cheng WC, Wong CH, Ma C. Crystal structure of the membrane-bound bifunctional transglycosylase PBP1b from Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 106: 8824-9. PMID 19458048 DOI: 10.1073/Pnas.0904030106  0.284
1989 Wang Y, Chen S, Liu KK, Wong C. Lipase-catalyzed irreversible transesterification using enol esters: Resolution of cyanohydrins and syntheses of ethyl (R)-2-hydroxy-4-phenylbutyrate and (S)-propranolol Tetrahedron Letters. 30: 1917-1920. DOI: 10.1016/S0040-4039(00)99613-8  0.284
2002 Mong KK, Wong CH. Reactivity-based one-pot synthesis of a Lewis Y carbohydrate hapten: a colon-rectal cancer antigen determinant. Angewandte Chemie (International Ed. in English). 41: 4087-90. PMID 12412090 DOI: 10.1002/1521-3773(20021104)41:21<4087::Aid-Anie4087>3.0.Co;2-X  0.284
2010 Liu CY, Guo CW, Chang YF, Wang JT, Shih HW, Hsu YF, Chen CW, Chen SK, Wang YC, Cheng TJ, Ma C, Wong CH, Fang JM, Cheng WC. Synthesis and evaluation of a new fluorescent transglycosylase substrate: lipid II-based molecule possessing a dansyl-C20 polyprenyl moiety. Organic Letters. 12: 1608-11. PMID 20187630 DOI: 10.1021/Ol100338V  0.283
2010 Fu H, Shen G, Wong C. Asymmetric epoxidation of allyl alcohol derivatives by ω‐hydroxylase from Pseudomonas oleovorans Recueil Des Travaux Chimiques Des Pays-Bas. 110: 167-170. DOI: 10.1002/Recl.19911100506  0.283
1986 Durrwachter J, Sweers H, Nozaki K, Wong C. Enzymatic aldol reaction/isomerization as a route to unusual sugars Tetrahedron Letters. 27: 1261-1264. DOI: 10.1016/S0040-4039(00)84233-1  0.283
2000 Vincent SP, Schleyer aA, Wong C. Asymmetric Strecker synthesis of C-glycopeptide. Journal of Organic Chemistry. 65: 4440-4443. PMID 10891150 DOI: 10.1021/Jo000034P  0.283
2013 Huang HW, Chen CH, Lin CH, Wong CH, Lin KI. B-cell maturation antigen is modified by a single N-glycan chain that modulates ligand binding and surface retention. Proceedings of the National Academy of Sciences of the United States of America. 110: 10928-33. PMID 23776238 DOI: 10.1073/Pnas.1309417110  0.283
1995 Gijsen HJM, Wong C. Sequential Three- and Four-Substrate Aldol Reactions Catalyzed by Aldolases Journal of the American Chemical Society. 117: 7585-7591. DOI: 10.1021/Ja00134A001  0.282
2015 Lin TW, Chang HT, Chen CH, Chen CH, Lin SW, Hsu TL, Wong CH. Galectin-3 binding protein and galactin-1 interaction in breast cancer cell aggregation and metastasis. Journal of the American Chemical Society. PMID 26168351 DOI: 10.1021/Jacs.5B04744  0.282
2015 Huang YL, Pai FS, Tsou YT, Mon HC, Hsu TL, Wu CY, Chou TY, Yang WB, Chen CH, Wong CH, Hsieh SL. Human CLEC18 gene cluster contains C-type lectins with differential glycan-binding specificity. The Journal of Biological Chemistry. PMID 26170455 DOI: 10.1074/Jbc.M115.649814  0.282
2005 Brik A, Alexandratos J, Lin Y, Elder JH, Olson AJ, Wlodawer A, Goodsell DS, Wong C. Cover Picture: 1,2,3-Triazole as a Peptide Surrogate in the Rapid Synthesis of HIV-1 Protease Inhibitors (ChemBioChem 7/2005) Chembiochem. 6: 1137-1137. DOI: 10.1002/Cbic.200590021  0.281
2015 Danishefsky SJ, Shue YK, Chang MN, Wong CH. Development of Globo-H cancer vaccine. Accounts of Chemical Research. 48: 643-52. PMID 25665650 DOI: 10.1021/Ar5004187  0.281
2000 Lin YC, Beck Z, Lee T, Le VD, Morris GM, Olson AJ, Wong CH, Elder JH. Alteration of substrate and inhibitor specificity of feline immunodeficiency virus protease Journal of Virology. 74: 4710-4720. PMID 10775609 DOI: 10.1128/Jvi.74.10.4710-4720.2000  0.281
1995 DeFrees SA, Kosch W, Way W, Paulson JC, Sabesan S, Halcomb RL, Huang D, Ichikawa Y, Wong C. Ligand Recognition by E-Selectin: Synthesis, Inhibitory Activity and Conformational Analysis of Bivalent Sialyl Lewis x Analogs Journal of the American Chemical Society. 117: 66-79. DOI: 10.1021/Ja00106A008  0.281
1999 Weitz-Schmidt G, Gong KW, Wong C. Selectin/Glycoconjugate Binding Assays For The Identification And Optimization Of Selectin Antagonists Analytical Biochemistry. 273: 81-88. PMID 10452802 DOI: 10.1006/Abio.1999.4180  0.281
1998 Lee T, Laco GS, Torbett BE, Fox HS, Lerner DL, Elder JH, Wong CH. Analysis of the S3 and S3' subsite specificities of feline immunodeficiency virus (FIV) protease: development of a broad-based protease inhibitor efficacious against FIV, SIV, and HIV in vitro and ex vivo. Proceedings of the National Academy of Sciences of the United States of America. 95: 939-44. PMID 9448264 DOI: 10.1073/Pnas.95.3.939  0.28
2010 Schelwies M, Brinson D, Otsuki S, Hong YH, Lotz MK, Wong CH, Hanson SR. Glucosamine-6-sulfamate analogues of heparan sulfate as inhibitors of endosulfatases. Chembiochem : a European Journal of Chemical Biology. 11: 2393-7. PMID 20973023 DOI: 10.1002/Cbic.201000401  0.28
2013 Bryk R, Arango N, Maksymiuk C, Balakrishnan A, Wu YT, Wong CH, Masquelin T, Hipskind P, Lima CD, Nathan C. Lipoamide channel-binding sulfonamides selectively inhibit mycobacterial lipoamide dehydrogenase. Biochemistry. 52: 9375-84. PMID 24251446 DOI: 10.1021/Bi401077F  0.28
1977 Wong C, Chen S, Wang K. The Resolution of Amino Acids by Enzymes Part 1: Proteolytic Enzyme Bromelain for Hydrolysis ofL-Amino Acid Methyl Esters Journal of the Chinese Chemical Society. 24: 129-133. DOI: 10.1002/Jccs.197700021  0.28
2000 Li M, Morris GM, Lee T, Laco GS, Wong CH, Olson AJ, Elder JH, Wlodawer A, Gustchina A. Structural studies of FIV and HIV-1 proteases complexed with an efficient inhibitor of FIV protease Proteins: Structure, Function and Genetics. 38: 29-40. PMID 10651036 DOI: 10.1002/(Sici)1097-0134(20000101)38:1<29::Aid-Prot4>3.0.Co;2-N  0.279
1994 Wang Y, Takaoka Y, Wong C. Remarkable Stereoselectivity in the Inhibition of α‐Galactosidase from Coffee Bean by a New Polyhydroxypyrrolidine Inhibitor Angewandte Chemie. 33: 1242-1244. DOI: 10.1002/Anie.199412421  0.279
1995 Lin C, Shimazaki M, Wong C, Koketsu M, Juneja LR, Kim M. Enzymatic synthesis of a sialyl Lewis X dimer from egg yolk as an inhibitor of E-selectin. Bioorganic & Medicinal Chemistry. 3: 1625-1630. PMID 8770386 DOI: 10.1016/0968-0896(95)00150-6  0.279
1998 Wong CH, Hendrix M, Manning DD, Rosenbohm C, Greenberg WA. A library approach to the discovery of small molecules that recognize RNA: Use of a 1,3-hydroxyamine motif as core Journal of the American Chemical Society. 120: 8319-8327. DOI: 10.1021/Ja980826P  0.279
1985 Matos JR, Smith MB, Wong C. Enantioselectivity of alcohol dehydrogenase-catalyzed oxidation of 1,2-diols and aminoalcohols☆ Bioorganic Chemistry. 13: 121-130. DOI: 10.1016/0045-2068(85)90014-8  0.279
2010 Shie JJ, Chen CA, Lin CC, Ku AF, Cheng TJ, Fang JM, Wong CH. Regioselective synthesis of di-C-glycosylflavones possessing anti-inflammation activities. Organic & Biomolecular Chemistry. 8: 4451-62. PMID 20725659 DOI: 10.1039/C0Ob00011F  0.279
2017 Chen CL, Hsu JC, Lin CW, Wang CH, Tsai MH, Wu CY, Wong CH, Ma C. Crystal structure of a homogeneous IgG-Fc glycoform with the N-glycan designed to maximize the antibody dependent cellular cytotoxicity. Acs Chemical Biology. PMID 28318221 DOI: 10.1021/Acschembio.7B00140  0.279
1994 Herrmann GF, Wang P, Shen G, Wong C. Recombinant Whole Cells as Catalysts for the Enzymatic Synthesis of Oligosaccharides and Glycopeptides Angewandte Chemie International Edition in English. 33: 1241-1242. DOI: 10.1002/Anie.199412411  0.279
2020 Lin CY, Wu HY, Hsu YL, Cheng TR, Liu JH, Huang RJ, Hsiao TH, Wang CJ, Hung PF, Lan A, Pan SH, Chein R, Wong CH, Yang PC. Suppression of Drug-Resistant Non-Small-Cell Lung Cancer with Inhibitors Targeting Minichromosomal Maintenance Protein. Journal of Medicinal Chemistry. PMID 32125853 DOI: 10.1021/Acs.Jmedchem.9B01783  0.278
1994 Halcomb RL, Fitz W, Wong C. Enzymatic synthesis of 7-deoxy-N-acetylneuraminic acid and 7-O-methyl-N-acetylneuraminic acid Tetrahedron: Asymmetry. 5: 2437-2442. DOI: 10.1016/S0957-4166(00)80390-0  0.278
1996 Fitz W, Rosenthal PB, Wong C. Synthesis and inhibitory properties of a thiomethylmercuric sialic acid with application to the X-ray structure determination of 9-O-acetylsialic acid esterase from influenza C virus Bioorganic & Medicinal Chemistry. 4: 1349-1353. PMID 8879557 DOI: 10.1016/0968-0896(96)00123-X  0.278
1995 Vassilev VP, Uchiyama T, Kajimoto T, Wong C. L-threonine aldolase in organic synthesis: Preparation of novel β-hydroxy-α-amino acids Tetrahedron Letters. 36: 4081-4084. DOI: 10.1016/0040-4039(95)00720-W  0.277
1991 Yuan W, Zhong Z, Wong C, Haeggström JZ, Wetterholm A, Samuelsson B. Probing the inhibition of leukotriene A4 hydrolase based on its aminopeptidase activity Bioorganic & Medicinal Chemistry Letters. 1: 551-556. DOI: 10.1016/S0960-894X(01)80464-9  0.277
1993 Kajimoto T, Takaoka Y, Wong C. S1.27 Synthesis of inhibitor forN-Acetylglucosaminyltransferase V Glycoconjugate Journal. 10: 228-228. DOI: 10.1007/Bf01209828  0.277
1994 Fotsch CH, Wong CH. Synthesis of a guanidino-sugar as a glycosyl cation mimic Tetrahedron Letters. 35: 3481-3484. DOI: 10.1016/S0040-4039(00)73215-1  0.277
2008 Tseng SY, Wang CC, Lin CW, Chen CL, Yu WY, Chen CH, Wu CY, Wong CH. Glycan arrays on aluminum-coated glass slides. Chemistry, An Asian Journal. 3: 1395-405. PMID 18683161 DOI: 10.1002/Asia.200800154  0.276
1979 Wong CH, Chen ST, Wang KT. Enzymic synthesis of opioid peptides. Biochimica Et Biophysica Acta. 576: 247-9. PMID 760808 DOI: 10.1016/0005-2795(79)90500-2  0.276
2000 Tsai C, Huang X, Wong C. Design and synthesis of cyclic sialyl Lewis X mimetics: a remarkable enhancement of inhibition by pre-organizing all essential functional groups ☆ Tetrahedron Letters. 41: 9499-9503. DOI: 10.1016/S0040-4039(00)01653-1  0.276
2002 Liu J, Wong C. Selectfluor™-mediated allylstannation of aldehydes and imines Tetrahedron Letters. 43: 3915-3917. DOI: 10.1016/S0040-4039(02)00640-8  0.275
2014 Hong BT, Chen CL, Fang JM, Tsai KC, Wang SY, Huang WI, Cheng YS, Wong CH. Oseltamivir hydroxamate and acyl sulfonamide derivatives as influenza neuraminidase inhibitors. Bioorganic & Medicinal Chemistry. 22: 6647-54. PMID 25456388 DOI: 10.1016/J.Bmc.2014.10.005  0.275
2002 Liu J, Wong C. An efficient method for the cleavage of p-methoxybenzylidene (PMP), tetrahydropyranyl (THP) and 1,3-dithiane protecting groups by Selectfluor™ Tetrahedron Letters. 43: 4037-4039. DOI: 10.1016/S0040-4039(02)00740-2  0.275
2011 Shie JJ, Fang JM, Lai PT, Wen WH, Wang SY, Cheng YS, Tsai KC, Yang AS, Wong CH. A practical synthesis of zanamivir phosphonate congeners with potent anti-influenza activity. Journal of the American Chemical Society. 133: 17959-65. PMID 21942552 DOI: 10.1021/Ja207892Q  0.275
2019 Huang MR, Hsu YL, Lin TC, Cheng TJ, Li LW, Tseng YW, Chou YS, Liu JH, Pan SH, Fang JM, Wong CH. Structure-guided development of purine amide, hydroxamate, and amidoxime for the inhibition of non-small cell lung cancer. European Journal of Medicinal Chemistry. 181: 111551. PMID 31376567 DOI: 10.1016/J.Ejmech.2019.07.054  0.275
2018 Lo PW, Shie JJ, Chen CH, Wu CY, Hsu TL, Wong CH. -GlcNAcylation regulates the stability and enzymatic activity of the histone methyltransferase EZH2. Proceedings of the National Academy of Sciences of the United States of America. PMID 29941599 DOI: 10.1073/Pnas.1801850115  0.275
2000 Saotome C, Kanie Y, Kanie O, Wong C. Synthesis and enzymatic evaluation of five-membered iminocyclitols and a pseudodisaccharide Bioorganic & Medicinal Chemistry. 8: 2249-2261. PMID 11026538 DOI: 10.1016/S0968-0896(00)00170-X  0.274
1996 Sears P, Wong CH. Intervention of carbohydrate recognition by proteins and nucleic acids. Proceedings of the National Academy of Sciences of the United States of America. 93: 12086-93. PMID 8901537 DOI: 10.1073/Pnas.93.22.12086  0.274
1988 West JB, Scholten J, Stolowich NJ, Hogg JL, Scott AI, Wong CH. Modification of proteases to esterases for peptide synthesis: methylchymotrypsin Journal of the American Chemical Society. 110: 3709-3710. DOI: 10.1021/Ja00219A083  0.274
1999 Kidd RD, Sears P, Huang DH, Witte K, Wong CH, Farber GK. Breaking the low barrier hydrogen bond in a serine protease. Protein Science : a Publication of the Protein Society. 8: 410-7. PMID 10048334 DOI: 10.1110/Ps.8.2.410  0.274
1997 Lin C, Murray BW, Ollmann IR, Wong C. Why is CMP-ketodeoxyoctonate highly unstable? Biochemistry. 36: 780-785. PMID 9020775 DOI: 10.1021/Bi962055C  0.274
2010 Chang CC, Ku AF, Tseng YY, Yang WB, Fang JM, Wong CH. 6,8-Di-C-glycosyl flavonoids from Dendrobium huoshanense. Journal of Natural Products. 73: 229-32. PMID 20055483 DOI: 10.1021/Np900252F  0.273
2009 Wang CC, Chen JR, Tseng YC, Hsu CH, Hung YF, Chen SW, Chen CM, Khoo KH, Cheng TJ, Cheng YS, Jan JT, Wu CY, Ma C, Wong CH. Glycans on influenza hemagglutinin affect receptor binding and immune response. Proceedings of the National Academy of Sciences of the United States of America. 106: 18137-42. PMID 19822741 DOI: 10.1073/Pnas.0909696106  0.273
2011 Liu KC, Lee PS, Wang SY, Cheng YS, Fang JM, Wong CH. Intramolecular ion-pair prodrugs of zanamivir and guanidino-oseltamivir. Bioorganic & Medicinal Chemistry. 19: 4796-802. PMID 21778065 DOI: 10.1016/J.Bmc.2011.06.080  0.272
1987 West JB, Wong CH. Use of nonproteases in peptide synthesis Tetrahedron Letters. 28: 1629-1632. DOI: 10.1016/S0040-4039(00)95377-2  0.272
1996 Hendrix M, Wong C. A chemoenzymatic approach to carbohydrate-mediated cell adhesion Pure and Applied Chemistry. 68: 2081-2087. DOI: 10.1351/Pac199668112081  0.272
2014 Chen YS, Yu HM, Shie JJ, Cheng TJ, Wu CY, Fang JM, Wong CH. Chemical constituents of Plectranthus amboinicus and the synthetic analogs possessing anti-inflammatory activity. Bioorganic & Medicinal Chemistry. 22: 1766-72. PMID 24491635 DOI: 10.1016/J.Bmc.2014.01.009  0.272
1994 Hiranuma S, Kajimoto T, Wong C. A facile synthesis of 1-thiopentofuranoside Tetrahedron Letters. 35: 5257-5260. DOI: 10.1016/S0040-4039(00)77078-X  0.271
2020 Chang YH, Wu JC, Yu HM, Hsu HT, Wu YT, Yu AL, Yu CT, Wong CH. Design and synthesis of glyco-peptides as anti-cancer agents targeting thrombin-protease activated receptor-1 interaction. Chemical Communications (Cambridge, England). PMID 32329494 DOI: 10.1039/D0Cc01240H  0.271
2015 Ke YY, Tsai CH, Yu HM, Jao YC, Fang JM, Wong CH. Latifolicinin A from a Fermented Soymilk Product and the Structure-Activity Relationship of Synthetic Analogues as Inhibitors of Breast Cancer Cell Growth. Journal of Agricultural and Food Chemistry. PMID 26499209 DOI: 10.1021/Acs.Jafc.5B04028  0.271
1994 Provencher L, Steensma DH, Wong C. Five-membered ring azasugars as potent inhibitors of α-L-rhamnosidase (naringinase) from Penicillium decumbens Bioorganic & Medicinal Chemistry. 2: 1179-1188. PMID 7757415 DOI: 10.1016/S0968-0896(00)82069-6  0.271
2002 Guo CT, Sun XL, Kanie O, Shortridge KF, Suzuki T, Miyamoto D, Hidari KI, Wong CH, Suzuki Y. An O-glycoside of sialic acid derivative that inhibits both hemagglutinin and sialidase activities of influenza viruses. Glycobiology. 12: 183-90. PMID 11971862 DOI: 10.1093/Glycob/12.3.183  0.271
2004 Cheng TJ, Brik A, Wong CH, Kan CC. Model system for high-throughput screening of novel human immunodeficiency virus protease inhibitors in Escherichia coli Antimicrobial Agents and Chemotherapy. 48: 2437-2447. PMID 15215092 DOI: 10.1128/Aac.48.7.2437-2447.2004  0.27
2004 Hanson SR, Best MD, Wong C. Sulfatasen: Struktur, Mechanismus, biologische Aktivität, Inhibition, Anwendung in Synthesen Angewandte Chemie. 116: 5858-5886. DOI: 10.1002/Ange.200300632  0.27
2017 Tseng TH, Lin TW, Chen CY, Chen CH, Lin JL, Hsu TL, Wong CH. Substrate Preference and Interplay of Fucosyltransferase 8 and N-Acetylglucosaminyltransferases. Journal of the American Chemical Society. PMID 28678517 DOI: 10.1021/Jacs.7B03729  0.27
2005 Numa MM, Lee LV, Hsu CC, Bower KE, Wong CH. Identification of novel anthrax lethal factor inhibitors generated by combinatorial Pictet-Spengler reaction followed by screening in situ. Chembiochem : a European Journal of Chemical Biology. 6: 1002-6. PMID 15880659 DOI: 10.1002/Cbic.200500009  0.27
2006 Lin YC, Brik A, de Parseval A, Tam K, Torbett BE, Wong CH, Elder JH. Altered gag polyprotein cleavage specificity of feline immunodeficiency virus/human immunodeficiency virus mutant proteases as demonstrated in a cell-based expression system. Journal of Virology. 80: 7832-43. PMID 16873240 DOI: 10.1128/Jvi.00374-06  0.27
1998 Rosenthal PB, Zhang X, Formanowski F, Fitz W, Wong CH, Meier-Ewert H, Skehel JJ, Wiley DC. Structure of the haemagglutinin-esterase-fusion glycoprotein of influenza C virus. Nature. 396: 92-6. PMID 9817207 DOI: 10.1038/23974  0.269
2014 Chen CL, Lin TC, Wang SY, Shie JJ, Tsai KC, Cheng YS, Jan JT, Lin CJ, Fang JM, Wong CH. Tamiphosphor monoesters as effective anti-influenza agents. European Journal of Medicinal Chemistry. 81: 106-18. PMID 24836064 DOI: 10.1016/J.Ejmech.2014.04.082  0.269
1991 Wong CH, Krach T, Gautheron-Le Narvor C, Ichikawa Y, Look GC, Gaeta F, Thompson D, Nicolaou KC. Synthesis of novel disaccharides based on glycosyltransferases: β1,4galactosyltransferase Tetrahedron Letters. 32: 4867-4870. DOI: 10.1016/S0040-4039(00)93482-8  0.269
1995 Slee DH, Laslo KL, Elder JH, Ollmann IR, Gustchina A, Kervinen J, Zdanov A, Wlodawer A, Wong C. Selectivity in the Inhibition of HIV and FIV Protease: Inhibitory and Mechanistic Studies of Pyrrolidine-Containing .alpha.-Keto Amide and Hydroxyethylamine Core Structures Journal of the American Chemical Society. 117: 11867-11878. DOI: 10.1021/Ja00153A008  0.269
2005 Sawkar AR, Adamski-Werner SL, Cheng WC, Wong CH, Beutler E, Zimmer KP, Kelly JW. Gaucher disease-associated glucocerebrosidases show mutation-dependent chemical chaperoning profiles. Chemistry & Biology. 12: 1235-44. PMID 16298303 DOI: 10.1016/J.Chembiol.2005.09.007  0.268
2014 Sauer AK, Liang CH, Stech J, Peeters B, Quéré P, Schwegmann-Wessels C, Wu CY, Wong CH, Herrler G. Characterization of the sialic acid binding activity of influenza A viruses using soluble variants of the H7 and H9 hemagglutinins. Plos One. 9: e89529. PMID 24586849 DOI: 10.1371/Journal.Pone.0089529  0.268
2009 Liang CH, Wang CC, Lin YC, Chen CH, Wong CH, Wu CY. Iron oxide/gold core/shell nanoparticles for ultrasensitive detection of carbohydrate-protein interactions. Analytical Chemistry. 81: 7750-6. PMID 19689135 DOI: 10.1021/Ac9012286  0.268
2013 Lin SC, Jan JT, Dionne B, Butler M, Huang MH, Wu CY, Wong CH, Wu SC. Different immunity elicited by recombinant H5N1 hemagglutinin proteins containing pauci-mannose, high-mannose, or complex type N-glycans. Plos One. 8: e66719. PMID 23799128 DOI: 10.1371/Journal.Pone.0066719  0.267
2004 Tolbert TJ, Wong CH. Subtilisin-catalyzed glycopeptide condensation. Methods in Molecular Biology (Clifton, N.J.). 283: 267-79. PMID 15197318 DOI: 10.1385/1-59259-813-7:267  0.267
2002 Demura M, Noda M, Kajimoto T, Uchiyama T, Umemoto K, Wong C, Asakura T. Solution structure of sialyl Lewis X mimics studied by two-dimensional NMR Journal of Molecular Structure. 602: 215-222. DOI: 10.1016/S0022-2860(01)00678-0  0.267
2018 Zhou T, Zheng A, Baxa U, Chuang GY, Georgiev IS, Kong R, O'Dell S, Shahzad-Ul-Hussan S, Shen CH, Tsybovsky Y, Bailer RT, Gift SK, Louder MK, McKee K, Rawi R, ... ... Wong CH, et al. A Neutralizing Antibody Recognizing Primarily N-linked Glycan Targets the Silent Face of the HIV Envelope. Immunity. PMID 29548671 DOI: 10.1016/J.Immuni.2018.02.013  0.267
2001 Mak CC, Le VD, Lin YC, Elder JH, Wong CH. Design, synthesis, and biological evaluation of HIV/FIV protease inhibitors incorporating a conformationally constrained macrocycle with a small P3′ residue Bioorganic and Medicinal Chemistry Letters. 11: 219-222. PMID 11206463 DOI: 10.1016/S0960-894X(00)00641-7  0.267
2016 Hsu CH, Park S, Mortenson DE, Foley BL, Wang X, Woods RJ, Case DA, Powers ET, Wong CH, Dyson HJ, Kelly JW. The Dependence of Carbohydrate-Aromatic Interaction Strengths on the Structure of the Carbohydrate. Journal of the American Chemical Society. PMID 27249581 DOI: 10.1021/Jacs.6B02879  0.266
1987 Matos JR, West JB, Wong C. Lipase catalysed synthesis of peptides: Preparation of a penicillin G precursor and other peptides Biotechnology Letters. 9: 233-236. DOI: 10.1007/Bf01027155  0.266
1994 Fitz W, Wong C. Combined Use of Subtilisin and N-Acetylneuraminic Acid Aldolase for the Synthesis of a Fluorescent Sialic Acid The Journal of Organic Chemistry. 59: 8279-8280. DOI: 10.1021/Jo00105A057  0.266
2014 Lee HY, Chen CY, Tsai TI, Li ST, Lin KH, Cheng YY, Ren CT, Cheng TJ, Wu CY, Wong CH. Immunogenicity study of Globo H analogues with modification at the reducing or nonreducing end of the tumor antigen. Journal of the American Chemical Society. 136: 16844-53. PMID 25371992 DOI: 10.1021/Ja508040D  0.266
1990 Hsu S, Wu S, Wang Y, Wong C. Lipase-catalyzed irreversible transesterification using enol esters: XAD-8 immobilized lipoprotein lipase-catalyzed resolution of secondary alcohols Tetrahedron Letters. 31: 6403-6406. DOI: 10.1016/S0040-4039(00)97076-X  0.265
1999 Zhang X, Rosenthal PB, Formanowski F, Fitz W, Wong CH, Meier-Ewert H, Skehel JJ, Wiley DC. X-ray crystallographic determination of the structure of the influenza C virus haemagglutinin-esterase-fusion glycoprotein. Acta Crystallographica. Section D, Biological Crystallography. 55: 945-61. PMID 10216291 DOI: 10.1107/S0907444999000232  0.265
2009 Wong CH. Enzymes for glycoprotein synthesis Chimia. 63: 318-326. DOI: 10.2533/Chimia.2009.318  0.265
2002 Mitchell ML, Tian F, Lee LV, Wong CH. Synthesis and evaluation of transition-state analogue inhibitors of alpha-1,3-fucosyltransferase. Angewandte Chemie (International Ed. in English). 41: 3041-4. PMID 12203452 DOI: 10.1002/1521-3773(20020816)41:16<3041::Aid-Anie3041>3.0.Co;2-V  0.265
2010 Su CY, Cheng TJ, Lin MI, Wang SY, Huang WI, Lin-Chu SY, Chen YH, Wu CY, Lai MM, Cheng WC, Wu YT, Tsai MD, Cheng YS, Wong CH. High-throughput identification of compounds targeting influenza RNA-dependent RNA polymerase activity. Proceedings of the National Academy of Sciences of the United States of America. 107: 19151-6. PMID 20974907 DOI: 10.1073/Pnas.1013592107  0.265
1992 Bradshaw CW, Lalonde JJ, Wong CH. Enzymatic synthesis of (R) and (S) 1-deuterohexanol Applied Biochemistry and Biotechnology. 33: 15-24. PMID 1416953 DOI: 10.1007/Bf02922180  0.265
1978 Wong C, Wang K. The Mutual Resoluton of Dl‐ephedrine and N‐Benzyloxycarbonyl‐Dl‐Amino Acids Journal of the Chinese Chemical Society. 25: 209-214. DOI: 10.1002/Jccs.197800034  0.264
2016 Wang PC, Fang JM, Tsai KC, Wang SY, Huang WI, Tseng YC, Cheng YE, Cheng TR, Wong CH. Peramivir Phosphonate Derivatives as Influenza Neuraminidase Inhibitors. Journal of Medicinal Chemistry. PMID 27167096 DOI: 10.1021/Acs.Jmedchem.6B00029  0.264
1996 Lin C, Kimura T, Wu S, Weitz-Schmidt G, Wong C. Liposome-like fucopeptides as sialyl lewis X mimetics Bioorganic & Medicinal Chemistry Letters. 6: 2755-2760. DOI: 10.1016/S0960-894X(96)00509-4  0.263
2000 Sheppard TL, Wong CH, Joyce GF. Nucleoglycoconjugates: design and synthesis of a new class of DNA-carbohydrate conjugates. Angewandte Chemie (International Ed. in English). 39: 3660-3. PMID 11091431 DOI: 10.1002/1521-3773(20001016)39:20<3660::Aid-Anie3660>3.0.Co;2-L  0.263
1998 Kamitakahara H, Suzuki T, Nishigori N, Suzuki Y, Kanie O, Wong CH. A Lysoganglioside/Poly-L-glutamic Acid Conjugate as a Picomolar Inhibitor of Influenza Hemagglutinin. Angewandte Chemie (International Ed. in English). 37: 1524-1528. PMID 29710929 DOI: 10.1002/(Sici)1521-3773(19980619)37:11<1524::Aid-Anie1524>3.0.Co;2-D  0.263
1995 Stura EA, Ghosh S, Garcia-Junceda E, Chen L, Wong CH, Wilson IA. Crystallization and preliminary crystallographic data for class I deoxyribose-5-phosphate aldolase from Escherichia coli: an application of reverse screening. Proteins. 22: 67-72. PMID 7675789 DOI: 10.1002/Prot.340220110  0.263
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