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David R. Kearns - Publications

Affiliations: 
University of California, San Diego, La Jolla, CA 
Area:
biophysical chemistry
Website:
http://www-chem.ucsd.edu/faculty/profiles/kearns_david_r.html

48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2000 Liu W, Vu HM, Geiduschek EP, Kearns DR. Solution structure of a mutant of transcription factor 1: implications for enhanced DNA binding. Journal of Molecular Biology. 302: 821-30. PMID 10993726 DOI: 10.1006/Jmbi.2000.4084  0.337
2000 Vu HM, Liu W, Grove A, Geiduschek EP, Kearns DR. Mechanisms for the enhanced thermal stability of a mutant of transcription factor 1 as explained by (1)H, (15)N and (13)C NMR chemical shifts and secondary structure analysis. Biochimica Et Biophysica Acta. 1478: 113-24. PMID 10719180 DOI: 10.1016/S0167-4838(99)00252-6  0.336
1996 Jia X, Grove A, Ivancic M, Hsu VL, Geiduscheck EP, Kearns DR. Structure of the Bacillus subtilis phage SPO1-encoded type II DNA-binding protein TF1 in solution. Journal of Molecular Biology. 263: 259-68. PMID 8913305 DOI: 10.1006/Jmbi.1996.0573  0.325
1995 Hsu VL, Jia X, Kearns DR. Multidimensional NMR spectroscopy of DNA-binding proteins: structure and function of a transcription factor. Toxicology Letters. 82: 577-89. PMID 8597113 DOI: 10.1016/0378-4274(95)03585-0  0.344
1994 Brown DR, Kurz M, Kearns DR, Hsu VL. Formation of multiple complexes between actinomycin D and a DNA hairpin: structural characterization by multinuclear NMR. Biochemistry. 33: 651-64. PMID 8292593 DOI: 10.1021/bi00169a005  0.448
1994 Jia X, Reisman JM, Hsu VL, Geiduschek EP, Parello J, Kearns DR. Proton and nitrogen NMR sequence-specific assignments and secondary structure determination of the Bacillus subtilis SPO1-encoded transcription factor 1. Biochemistry. 33: 8842-52. PMID 8038176 DOI: 10.1021/Bi00195A028  0.324
1993 Reisman JM, Hsu VL, Jariel-Encontre I, Lecou C, Sayre MH, Kearns DR, Parello J. A 1H-NMR study of the transcription factor 1 from Bacillus subtilis phage SPO1 by selective 2H-labeling. Complete assignment and structural analysis of the aromatic resonances for a 22-kDa homodimer. European Journal of Biochemistry / Febs. 213: 865-73. PMID 8477755 DOI: 10.1111/J.1432-1033.1993.Tb17830.X  0.354
1992 Tsang P, Kearns DR, Vold RR. Deuterium quadrupole echo NMR spectra and spin-lattice relaxation of synthetic polyribonucleotides Journal of the American Chemical Society. 114: 6585-6587. DOI: 10.1021/Ja00042A064  0.307
1991 Ni Y, Siegel JS, Hsu VL, Kearns DR. Torsional angle and conformation in 2-vinylanthracene studied by NMR spectroscopy and MO calculations Journal of Physical Chemistry. 95: 9211-9213. DOI: 10.1021/J100176A034  0.305
1989 Härd T, Sayre MH, Geiduschek EP, Kearns DR. A type II DNA-binding protein genetically engineered for fluorescence spectroscopy: the "arm" of transcription factor 1 binds in the DNA grooves. Biochemistry. 28: 2813-9. PMID 2742813 DOI: 10.1021/Bi00433A011  0.358
1989 Härd T, Hsu V, Sayre MH, Geiduschek EP, Appelt K, Kearns DR. Fluorescence studies of a single tyrosine in a type II DNA binding protein. Biochemistry. 28: 396-406. PMID 2706265 DOI: 10.1021/Bi00427A055  0.366
1989 Härd T, Fan P, Magde D, Kearns DR. On the flexibility of DNA: Time-resolved fluorescence polarization of intercalated quinacrine and 9-amino-6-chloro-2-methoxyacridine Journal of Physical Chemistry®. 93: 4338-4345. DOI: 10.1021/J100347A085  0.322
1988 Brandes R, Vold RR, Kearns DR, Rupprecht A. A 2H-NMR study of the A-DNA conformation in films of oriented Na-DNA: evidence of a disordered B-DNA contribution. Biopolymers. 27: 1159-70. PMID 3207852 DOI: 10.1002/Bip.360270709  0.364
1988 Brandes R, Vold RR, Kearns DR, Rupprecht A. Static disorder and librational motions of the purine bases in films of oriented Li-DNA. Journal of Molecular Biology. 202: 321-32. PMID 3172220 DOI: 10.1016/0022-2836(88)90461-5  0.302
1986 Ikuta S, Chattopadhyaya R, Ito H, Dickerson RE, Kearns DR. NMR study of a synthetic DNA hairpin. Biochemistry. 25: 4840-9. PMID 3768317 DOI: 10.1021/Bi00365A018  0.347
1986 Mirau PA, Kearns DR, McIntosh LP, Jovin TM. 1H nuclear magnetic resonance study of the dynamic properties of the B and Z-forms of poly[d(A-br5C).d(G-T)]. Journal of Molecular Biology. 192: 633-43. PMID 3031314 DOI: 10.1016/0022-2836(86)90281-0  0.31
1986 Brandes R, Vold RR, Vold RL, Kearns DR. Effects of hydration on purine motion in solid DNA. Biochemistry. 25: 7744-51. PMID 3026460 DOI: 10.1021/Bi00371A069  0.309
1986 Vold RR, Brandes R, Tsang P, Kearns DR, Vold RL, Rupprecht A. Deuterium NMR spectra and librational motions of the base pairs in oriented calf thymus DNA Journal of the American Chemical Society. 108: 302-303. DOI: 10.1021/Ja00262A023  0.365
1985 Leupin W, Feigon J, Denny WA, Kearns DR. Substituent effects on the binding of ethidium and its derivatives to natural DNA. Biophysical Chemistry. 22: 299-305. PMID 4063454 DOI: 10.1016/0301-4622(85)80053-3  0.598
1984 Feigon J, Denny WA, Leupin W, Kearns DR. Interactions of antitumor drugs with natural DNA: 1H NMR study of binding mode and kinetics. Journal of Medicinal Chemistry. 27: 450-65. PMID 6708048 DOI: 10.1021/Jm00370A007  0.57
1984 Lerner DB, Becktel WJ, Everett R, Goodman M, Kearns DR. Solvation effects on the 31P-NMR chemical shifts and infrared spectra of phosphate diesters. Biopolymers. 23: 2157-72. PMID 6498296 DOI: 10.1002/Bip.360231105  0.473
1984 FEIGON J, DENNY WA, LEUPIN W, KEARNS DR. ChemInform Abstract: INTERACTIONS OF ANTITUMOR DRUGS WITH NATURAL DNA: PROTON NMR STUDY OF BINDING MODE AND KINETICS Chemischer Informationsdienst. 15. DOI: 10.1002/Chin.198438361  0.584
1983 Feigon J, Leupin W, Denny WA, Kearns DR. Two-dimensional proton nuclear magnetic resonance investigation of the synthetic deoxyribonucleic acid decamer d(ATATCGATAT)2. Biochemistry. 22: 5943-51. PMID 6661418 DOI: 10.1021/Bi00294A038  0.577
1983 Feigon J, Denny WA, Leupin W, Kearns DR. Proton nuclear magnetic resonance investigation of the conformation and dynamics in the synthetic deoxyribonucleic acid decamers d(ATATCGATAT) and d(ATATGCATAT). Biochemistry. 22: 5930-42. PMID 6661417 DOI: 10.1021/Bi00294A037  0.592
1983 Feigon J, Wright JM, Denny WA, Leupin W, Kearns DR. Application of multiple-pulse H-NMR techniques to the study of two synthetic DNA decamers. Cold Spring Harbor Symposia On Quantitative Biology. 47: 207-17. PMID 6574841 DOI: 10.1101/Sqb.1983.047.01.026  0.522
1983 FEIGON J, WRIGHT JM, LEUPIN W, DENNY WA, KEARNS DR. ChemInform Abstract: USE OF TWO-DIMENSIONAL NMR IN THE STUDY OF A DOUBLE-STRANDED DNA DECAMER Chemischer Informationsdienst. 14. DOI: 10.1002/Chin.198301053  0.593
1982 Feigon J, Leupin W, Denny WA, Kearns DR. Binding of ethidium derivatives to natural DNA: a 300 MHz 1H NMR study. Nucleic Acids Research. 10: 749-62. PMID 7063414 DOI: 10.1093/Nar/10.2.749  0.56
1982 Granot J, Feigon J, Kearns DR. Interactions of DNA with divalent metal ions. I. 31P-NMR studies. Biopolymers. 21: 181-201. PMID 7055631 DOI: 10.1002/Bip.360210115  0.552
1982 Feigon J, Wright JM, Leupin W, Denny WA, Kearns DR. Use of two-dimensional NMR in the study of a double-stranded DNA decamer Journal of the American Chemical Society. 104: 5540-5541. DOI: 10.1021/Ja00384A069  0.592
1981 Early TA, Kearns DR, Hillen W, Wells RD. A 300-MHz proton nuclear magnetic resonance investigation of deoxyribonucleic acid restriction fragments: dynamic properties. Biochemistry. 20: 3764-9. PMID 6268145 DOI: 10.1021/Bi00516A015  0.302
1981 Early TA, Kearns DR, Hillen W, Wells RD. A 300- and 600-MHz proton nuclear magnetic resonance investigation of a 12 base pair deoxyribonucleic acid restriction fragment: relaxation behavior of the low-field resonances in water. Biochemistry. 20: 3756-64. PMID 6268144 DOI: 10.1021/Bi00516A014  0.312
1981 Wright JM, Feigon J, Denny W, Leupin W, Kearns DR. Use of the time-shared Redfield 214 pulse method to measure relaxation rates of imino protons of a double-stranded synthetic DNA decamer in water Journal of Magnetic Resonance (1969). 45: 514-519. DOI: 10.1016/0022-2364(81)90158-X  0.572
1980 Early TA, Kearns DR, Hillen W, Wells RD. A 300 MHz and 600 MHz proton NMR study of a 12 base pair restriction fragment: investigation of structure by relaxation measurements. Nucleic Acids Research. 8: 5795-812. PMID 6258152 DOI: 10.1093/Nar/8.23.5795  0.381
1980 Early TA, Feigon J, Kearns DR. Direct measurement of spin-spin and spin-lattice relaxation rates of exchangeable NH protons of DNA in water Journal of Magnetic Resonance (1969). 41: 343-348. DOI: 10.1016/0022-2364(80)90082-7  0.546
1979 Feigon J, Kearns DR. 1H NMR investigation of the conformational states of DNA in nucleosome core particles. Nucleic Acids Research. 6: 2327-37. PMID 461191 DOI: 10.1093/Nar/6.6.2327  0.588
1977 Early TA, Kearns DR, Burd JF, Larson JE, Wells RD. High resolution proton nuclear magnetic resonance investigation of the structural and dynamic properties of d(C15A15)-d(T15G15). Biochemistry. 16: 541-51. PMID 836800 DOI: 10.1021/Bi00622A031  0.369
1975 Jones CR, Kearns DR. Identification of a unique ethidium bromide binding site on yeast tRNAPhe by high resolution (300 MHz) nuclear magnetic resonance. Biochemistry. 14: 2660-5. PMID 1096934 DOI: 10.1021/Bi00683A016  0.327
1974 Jones CR, Kearns DR. Investigation of the structure of yeast tRNAphe by nuclear magnetic resonance: paramagnetic rare earth ion probes of structure. Proceedings of the National Academy of Sciences of the United States of America. 71: 4237-40. PMID 4610573 DOI: 10.1073/Pnas.71.10.4237  0.332
1974 Kearns DR, Wong YP, Chang SH, Hawkins E. Investigation of the structure of native and denatured conformations of tRNALeu3 by high-resolution nuclear magnetic resonance. Biochemistry. 13: 4736-46. PMID 4609465 DOI: 10.1021/Bi00720A009  0.306
1973 Wong YP, Reid BR, Kearns DR. Conformation of charged and uncharged tRNA. Proceedings of the National Academy of Sciences of the United States of America. 70: 2193-5. PMID 4599618 DOI: 10.1073/Pnas.70.8.2193  0.334
1973 Kearns DR, Wong KL, Wong YP. Effect of the removal of the Y base on the conformation of yeast tRNA. Proceedings of the National Academy of Sciences of the United States of America. 70: 3843-6. PMID 4590172 DOI: 10.1073/Pnas.70.12.3843  0.32
1973 Shulman RG, Hilbers CW, Wong YP, Wong KL, Lightfoot DR, Reid BR, Kearns DR. Determination of secondary and tertiary structural features of transfer RNA molecules in solution by nuclear magnetic resonance. Proceedings of the National Academy of Sciences of the United States of America. 70: 2042-5. PMID 4579011 DOI: 10.1073/Pnas.70.7.2042  0.337
1961 Kearns DR, Calvin M. Solid State Ionization Potentials of Some Aromatic Organic Compounds The Journal of Chemical Physics. 34: 2026-2030. DOI: 10.1063/1.1731815  0.366
1961 Kearns DR, Calvin M. Electrical Properties of Organic Solids. IV. Charge Carrier Diffusivity in Metal‐Free Phthalocyanine The Journal of Chemical Physics. 34: 2022-2025. DOI: 10.1063/1.1731814  0.366
1961 Kearns DR, Calvin M. Electrical and Magnetic Properties of Organic Molecular Solids. III. Violanthrene and Some Other Donors with the Acceptors o-Chloranil, Iodine and Tetracyanoethylene1 Journal of the American Chemical Society. 83: 2110-2121. DOI: 10.1021/ja01470a017  0.372
1960 Kearns DR, Tollin G, Calvin M. Electrical Properties of Organic Solids. II. Effects of Added Electron Acceptor on Metal‐Free Phthalocyanine The Journal of Chemical Physics. 32: 1020-1025. DOI: 10.1063/1.1730844  0.381
1960 Tollin G, Kearns DR, Calvin M. Electrical Properties of Organic Solids. I. Kinetics and Mechanism of Conductivity of Metal‐Free Phthalocyanine The Journal of Chemical Physics. 32: 1013-1019. DOI: 10.1063/1.1730843  0.383
1958 Kearns D, Calvin M. Photovoltaic Effect and Photoconductivity in Laminated Organic Systems The Journal of Chemical Physics. 29: 950-951. DOI: 10.1063/1.1744619  0.362
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